Photo-crosslinked copolymers of 2-hydroxyethyl methacrylate, poly(ethylene glycol) tetra-acrylate and ethylene dimethacrylate for improving biocompatibility of biosensors
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A copolymer containing 88% 2-hydroxyethyl methacrylate (HEMA), 9% poly(ethylene glycol) (MW 18.5 kDa) tetra-acrylate and 3% ethylene dimethacrylate was prepared and evaluated for use as a biocompatible interface between glucose biosensors and tissue in the rat. The glucose sensor utilizes glucose oxidase that is electrically 'wired' to a gold current collector by a reduction-oxidation polymer. Coatings of the copolymer were crosslinked in situ on the sensors using long wavelength ultraviolet light and 2,2-dimethoxy-2-phenyl-acetophenone as the initiator. The effect these films had on the current response to glucose was measured. Over a glucose concentration range of 0-30 mM, the average percentage decrease in response was 45 +/- 28% (mean +/- 95% confidence interval) at 37 degrees C for films that were about 0.1 mm thick, an acceptable value. Copolymer-treated and control electrodes were implanted in the intrascapular subcutaneous tissue of male Sprague-Dawley rats for three days. The explanted samples were evaluated using scanning electron microscopy. The control electrodes were highly encapsulated with fibrous material, while the copolymer-treated electrodes induced much less encapsulation. The results show this copolymer to be a candidate as a biocompatible coating for electrically wired oxidoreductase-based subcutaneous biosensors.
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Substrates with a hydrogel coating had markedly less fibrous encapsulation than controls after 3 days.
“substrates with the hydrogel coating had markedly less fibrous encapsulation relative to controls.143”
From Biocompatible Materials for Continuous Glucose Monitoring Devices (2013) · cites this paper as [143]
Cites
Design and in vitro studies of a needle-type glucose sensor for subcutaneous monitoring
Bindra, D. S., Zhang, Y., Wilson, G. S., Sternberg, R., Thevenot, D. R., Moatti, D., & Reach, G. (1991) · Analytical Chemistry · doi:10.1021/ac00017a008 · Cited by 309 · see citing works
Gregg, B. A., & Heller, A. (1991) · The Journal of Physical Chemistry · doi:10.1021/j100168a046 · Cited by 275 · see citing works
Self-citationDesai, N. P., & Hubbell, J. A. (1991) · Biomaterials · doi:10.1016/0142-9612(91)90193-e · Cited by 265 · see citing works
Self-citationRapid photopolymerization of immunoprotective gels in contact with cells and tissue
Pathak, C. P., Sawhney, A. S., & Hubbell, J. A. (1992) · Journal of the American Chemical Society · doi:10.1021/ja00047a065 · Cited by 182 · see citing works
Self-citationApplication of Chronic Intravascular Blood Glucose Sensor in Dogs
Armour, J. C., Lucisano, J. Y., Bd, M., & Gough, D. A. (1990) · Diabetes · doi:10.2337/diab.39.12.1519 · Cited by 175 · see citing works
Sawhney, A. S., & Hubbell, J. A. (1992) · Biomaterials · doi:10.1016/0142-9612(92)90180-v · Cited by 156 · see citing works
Self-citationPishko, M. V., Michael, A. C., & Heller, A. (1991) · Analytical Chemistry · doi:10.1021/ac00020a014 · Cited by 148 · see citing works
Self-citationGombotz, W. R., Guanghui, W., & Hoffman, A. (1989) · Journal of Applied Polymer Science · doi:10.1002/app.1989.070370108 · Cited by 123 · see citing works
Elimination of electrooxidizable interferant-produced currents in amperometric biosensors
Maidan, R., & Heller, A. (1992) · Analytical Chemistry · doi:10.1021/ac00047a003 · Cited by 117 · see citing works
Self-citationPickup, J. C., Shaw, G. W., & Claremont, D. J. (1989) · Diabetologia · doi:10.1007/bf00265097 · Cited by 114 · see citing works
Csöregi, E., Quinn, C. P., Schmidtke, D. W., Lindquist, S., Pishko, M. V., Ye, L., Katakis, I., Hubbell, J. A., & Heller, A. (1994) · Analytical Chemistry · doi:10.1021/ac00091a022 · Cited by 110 · see citing works
Self-citationPoitout, V., Moatti-Sirat, D., Reach, G., Zhang, Y., Wilson, G. S., Lemonnier, F., & Klein, J. C. (1993) · Diabetologia · doi:10.1007/bf00404077 · Cited by 95 · see citing works
Turner, R. F. B., Harrison, D. J., & Rojotte, R. V. (1991) · Biomaterials · doi:10.1016/0142-9612(91)90003-s · Cited by 91 · see citing works
Application of chronic intravascular blood glucose sensor in dogs
Armour, J. C., Lucisano, J. Y., Bd, M., et al. (1990) · Diabetes · doi:10.2337/diabetes.39.12.1519 · Cited by 74 · see citing works
In-vivo behaviour of hypodermically implanted microfabricated glucose sensors
Koudelka, M., Rohner‐Jeanrenaud, F., Terrettaz, J., Bobbioni-Harsch, E., de Rooij, N. F., & Jeanrenaud, B. (1991) · Biosensors and Bioelectronics · doi:10.1016/0956-5663(91)85005-h · Cited by 72 · see citing works
Grainger, D. W., Nojiri, C., Okano, T., & Kim, S. (1989) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820230903 · Cited by 54 · see citing works
Determination of urate in undiluted whole blood by enzyme electrode
Keedy, F. H., & Vadgama, P. M. (1991) · Biosensors and Bioelectronics · doi:10.1016/0956-5663(91)85046-y · Cited by 43 · see citing works
Poly(vinyl alcohol)-heparin hydrogels as sensor catheter membranes
Brinkman, E., Does, L. V. D., & Bantjes, A. (1991) · Biomaterials · doi:10.1016/0142-9612(91)90134-v · Cited by 34 · see citing works
Short-term in vivo operation of a glucose sensor.
Gough, D. A., Armour, J. C., Jy, L., & Bd, M. (1986) · PubMed · Cited by 21 · see citing works
Glucose electrochemical probe with extended linearity for whole blood
Mascini, M., Selleri, S., & Riviello, M. (1989) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/0731-7085(89)80158-x · Cited by 8 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Electrochemical Glucose Sensors and Their Applications in Diabetes Management
Heller, A., & Feldman, B. (2008) · Chemical Reviews · doi:10.1021/cr068069y · Cited by 1,707 · see citing works
Self-citationPhotopolymerizable hydrogels for tissue engineering applications
Nguyen, K. T., & West, J. L. (2002) · Biomaterials · doi:10.1016/s0142-9612(02)00175-8 · Cited by 1,669 · see citing works
Enzymatic Biofuel Cells for Implantable and Microscale Devices
Barton, S. C., Gallaway, J., & Atanassov, P. B. (2004) · Chemical Reviews · doi:10.1021/cr020719k · Cited by 1,396 · see citing works
Biosensors for real-time in vivo measurements
Wilson, G. S., & Gifford, R. (2005) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2004.12.003 · Cited by 660 · see citing works
Heller, A. (2004) · Physical Chemistry Chemical Physics · doi:10.1039/b313149a · Cited by 660 · see citing works
Self-citationFluorescence-based glucose sensors
Pickup, J. C., Hussain, F., Evans, N. D., Rolinski, O. J., & Birch, D. J. S. (2005) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2004.10.002 · Cited by 616 · see citing works
Biomaterials/Tissue Interactions: Possible Solutions to Overcome Foreign Body Response
Morais, J. M., Papadimitrakopoulos, F., & Burgess, D. J. (2010) · The AAPS Journal · doi:10.1208/s12248-010-9175-3 · Cited by 560 · see citing works
Methods for reducing biosensor membrane biofouling
Wisniewski, N., & Reichert, M. (2000) · Colloids and Surfaces B: Biointerfaces · doi:10.1016/s0927-7765(99)00148-4 · Cited by 543 · see citing works
Fabrication of Poly(ethylene glycol) Hydrogel Microstructures Using Photolithography
Revzin, A., Russell, R. J., Yadavalli, V. K., Koh, W., Deister, C. A., Hile, D. D., Mellott, M. B., & Pishko, M. V. (2001) · Langmuir · doi:10.1021/la010075w · Cited by 472 · see citing works
Onuki, Y., Bhardwaj, U., Papadimitrakopoulos, F., & Burgess, D. J. (2008) · Journal of Diabetes Science and Technology · doi:10.1177/193229680800200610 · Cited by 417 · see citing works
Mellott, M. B., Searcy, K., & Pishko, M. V. (2001) · Biomaterials · doi:10.1016/s0142-9612(00)00258-1 · Cited by 389 · see citing works
Biocompatible Materials for Continuous Glucose Monitoring Devices
Nichols, S. P., Koh, A., Storm, W. L., Shin, J. H., & Schoenfisch, M. H. (2013) · Chemical Reviews · doi:10.1021/cr300387j · Cited by 347 · see citing works
Engineering biomaterials to integrate and heal: The biocompatibility paradigm shifts
Bryers, J. D., Giachelli, C. M., & Ratner, B. D. (2012) · Biotechnology and Bioengineering · doi:10.1002/bit.24559 · Cited by 271 · see citing works
Electrochemistry in Diabetes Management
Heller, A., & Feldman, B. (2010) · Accounts of Chemical Research · doi:10.1021/ar9002015 · Cited by 255 · see citing works
Self-citation3D printing of inherently nanoporous polymers via polymerization-induced phase separation
Dong, Z., Cui, H., Zhang, H., Wang, F., Zhan, X., Mayer, F., Nestler, B., Wegener, M., & Levkin, P. A. (2021) · Nature Communications · doi:10.1038/s41467-020-20498-1 · Cited by 254 · see citing works
Implanted Electrochemical Glucose Sensors for the Management of Diabetes
Heller, A. (1999) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.1.1.153 · Cited by 215 · see citing works
Self-citationOverstreet, D. J., Dutta, D., Stabenfeldt, S. E., & Vernon, B. L. (2012) · Journal of Polymer Science Part B Polymer Physics · doi:10.1002/polb.23081 · Cited by 200 · see citing works
In vitro biocompatibility of biodegradable dextran-based hydrogels tested with human fibroblasts
Groot, C. J. D. (2001) · Biomaterials · doi:10.1016/s0142-9612(00)00266-0 · Cited by 184 · see citing works
Design of Multiresponsive Hydrogel Particles and Assemblies
Hendrickson, G. R., Smith, M. H., South, A. B., & Lyon, L. A. (2010) · Advanced Functional Materials · doi:10.1002/adfm.200902429 · Cited by 182 · see citing works
Anti-Inflammatory Polymeric Coatings for Implantable Biomaterials and Devices
Bridges, A. W., & Garcı́a, A. J. (2008) · Journal of Diabetes Science and Technology · doi:10.1177/193229680800200628 · Cited by 181 · see citing works
Hyun, D. C., Park, M., Park, C., Kim, B., Younan Xia, A., Hur, J. H., Kim, J. M., Park, J. J., & Jeong, U. (2011) · Advanced Materials · doi:10.1002/adma.201100639 · Cited by 179 · see citing works
Polymer integration for packaging of implantable sensors
Qin, Y., Howlader, M. M. R., Deen, M. J., Haddara, Y. M., & Selvaganapathy, P. R. (2014) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2014.05.063 · Cited by 163 · see citing works
Řı́hová, B. (1996) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(96)00404-8 · Cited by 161 · see citing works
Degradable dextran hydrogels: controlled release of a model protein from cylinders and microspheres
Franssen, O., Vandervennet, L., Roders, P., & Hennink, W. E. (1999) · Journal of Controlled Release · doi:10.1016/s0168-3659(99)00074-7 · Cited by 155 · see citing works
Nanocomposites: From Fabrications to Electrochemical Bioapplications
Xiao, Y., & Li, C. M. (2008) · Electroanalysis · doi:10.1002/elan.200704125 · Cited by 153 · see citing works
Implantable chemical sensors for real-time clinical monitoring: progress and challenges
Frost, M. C., & Meyerhoff, M. E. (2002) · Current Opinion in Chemical Biology · doi:10.1016/s1367-5931(02)00371-x · Cited by 148 · see citing works
Reduced acute inflammatory responses to microgel conformal coatings
Bridges, A. W., Singh, N., Burns, K. L., Babensee, J. E., Lyon, L. A., & Garcı́a, A. J. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.08.015 · Cited by 133 · see citing works
Design of a subcutaneous implantable biochip for monitoring of glucose and lactate
Guiseppi‐Elie, A., Brahim, S. I., Slaughter, G. E., & Ward, K. R. (2005) · IEEE Sensors Journal · doi:10.1109/jsen.2005.846173 · Cited by 129 · see citing works
Biocompatible, glucose-permeable hydrogel for in situ coating of implantable biosensors
Quinn, C. A. P., Connor, R. E., & Heller, A. (1997) · Biomaterials · doi:10.1016/s0142-9612(97)00125-7 · Cited by 126 · see citing works
Self-citationWang, W., Gao, S., & Wang, B. (1999) · Organic Letters · doi:10.1021/ol9908732 · Cited by 124 · see citing works
Approaches Toward Allowing Electroanalytical Devices to be Used in Biological Fluids
Barfidokht, A., & Gooding, J. J. (2014) · Electroanalysis · doi:10.1002/elan.201400097 · Cited by 120 · see citing works
Integrated medical feedback systems for drug delivery
Heller, A. (2005) · AIChE Journal · doi:10.1002/aic.10489 · Cited by 117 · see citing works
Self-citationJhaveri, S. J., McMullen, J. D., Sijbesma, R. P., Tan, L., Zipfel, W. R., & Ober, C. K. (2009) · Chemistry of Materials · doi:10.1021/cm803174e · Cited by 113 · see citing works
Myung, D. J., Koh, W., Bakri, A., Zhang, F., Marshall, A., Ko, J., Noolandi, J., Carrasco, M. R., Cochran, J. R., Frank, C. W., et al. (2007) · Biomedical Microdevices · doi:10.1007/s10544-006-9040-4 · Cited by 111 · see citing works
Use of hydrogel coating to improve the performance of implanted glucose sensors
Yu, B., Wang, C., Ju, Y. M., West, L., Harmon, J., Moussy, Y., & Moussy, F. (2008) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2007.11.010 · Cited by 105 · see citing works
Immobilization of multi-enzyme microreactors inside microfluidic devices
Koh, W., & Pishko, M. V. (2004) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2004.08.025 · Cited by 103 · see citing works
Scholten, K., & Meng, E. F. (2018) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2018.02.022 · Cited by 103 · see citing works
Sirkar, K., & Pishko, M. V. (1998) · Analytical Chemistry · doi:10.1021/ac971236x · Cited by 102 · see citing works
Building Fluorescent Sensors for Carbohydrates Using Template-Directed Polymerizations
Gao, S. (2001) · Bioorganic Chemistry · doi:10.1006/bioo.2001.1219 · Cited by 101 · see citing works
Polymeric “smart” coatings to prevent foreign body response to implantable biosensors
Wang, Y., Papadimitrakopoulos, F., & Burgess, D. J. (2013) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.12.028 · Cited by 100 · see citing works
Mass transfer in rapidly photopolymerized poly(ethylene glycol) hydrogels used for chemical sensing
Russell, R. J., Axel, A. C. S., Shields, K. L., & Pishko, M. V. (2001) · Polymer · doi:10.1016/s0032-3861(00)00851-x · Cited by 100 · see citing works
Seong, G. H., Zhan, W., & Crooks, R. M. (2002) · Analytical Chemistry · doi:10.1021/ac020069k · Cited by 99 · see citing works
Noninvasive and Minimally-Invasive Optical Monitoring Technologies
Coté, G. L. (2001) · Journal of Nutrition · doi:10.1093/jn/131.5.1596s · Cited by 84 · see citing works
Probing the Surface Structural Rearrangement of Hydrogels by Sum-Frequency Generation Spectroscopy
Chen, Q., Zhang, D., Somorjai, G. A., & Bertozzi, C. R. (1998) · Journal of the American Chemical Society · doi:10.1021/ja9831453 · Cited by 77 · see citing works
Fully Integrated Biochip Platforms for Advanced Healthcare
Carrara, S., Ghoreishizadeh, S. S., Olivo, J., Taurino, I., Baj-Rossi, C., Cavallini, A., de Beeck, M. O., Dehollain, C., Burleson, W. P., Moussy, F. G., et al. (2012) · Sensors · doi:10.3390/s120811013 · Cited by 76 · see citing works
Application of Semipermeable Membranes in Glucose Biosensing
Kulkarni, T., & Slaughter, G. E. (2016) · Membranes · doi:10.3390/membranes6040055 · Cited by 74 · see citing works
Gong, H. Y., Park, J., Kim, W., Kim, J., Lee, J. Y., & Koh, W. (2019) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b16005 · Cited by 71 · see citing works
Ju, Y. M., Yu, B., Koob, T. J., Moussy, Y., & Moussy, F. G. (2007) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.31756 · Cited by 70 · see citing works
Cryogelation for preparation of novel biodegradable tissue-engineering scaffolds
Bölgen, N., Plieva, F. M., Galaev, I. Y., Mattìasson, B., & Pişkın, E. (2007) · Journal of Biomaterials Science Polymer Edition · doi:10.1163/156856207781554064 · Cited by 69 · see citing works
Kim, Y. S., Cho, K., Lee, H. J., Chang, S., Lee, H., Kim, J. H., & Koh, W. (2016) · Reactive and Functional Polymers · doi:10.1016/j.reactfunctpolym.2016.09.003 · Cited by 69 · see citing works
Schmidtke, D. W., & Heller, A. (1998) · Analytical Chemistry · doi:10.1021/ac970932u · Cited by 65 · see citing works
Self-citationHeller, A. (1996) · Current Opinion in Biotechnology · doi:10.1016/s0958-1669(96)80094-2 · Cited by 65 · see citing works
Self-citationLee, W., Choi, D., Lee, Y., Kim, D. N., Park, J., & Koh, W. (2007) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2007.09.085 · Cited by 64 · see citing works
Synthesis, characterization and crosslinking of functional star‐shaped poly(ε‐caprolactone)
Turunen, M. P. K., Korhonen, H., Tuominen, J. U., & Seppälä, J. V. (2001) · Polymer International · doi:10.1002/pi.805 · Cited by 64 · see citing works
Liao, Y., Wang, W., & Wang, B. (1999) · Bioorganic Chemistry · doi:10.1006/bioo.1999.1151 · Cited by 62 · see citing works
Lee, H. J., & Koh, W. (2014) · ACS Applied Materials & Interfaces · doi:10.1021/am501714k · Cited by 61 · see citing works
An, S. Y., Bui, M.-P. N., Nam, Y. J., Han, K. N., Li, C. A., Choo, J., Lee, E. K., Katoh, S., Kumada, Y., & Seong, G. H. (2008) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2008.11.022 · Cited by 60 · see citing works
Basics of DNA biosensors and cancer diagnosis
Sohrabi, N., Valizadeh, A., Farkhani, S. M., & Akbarzadeh, A. (2014) · Artificial Cells Nanomedicine and Biotechnology · doi:10.3109/21691401.2014.976707 · Cited by 60 · see citing works
Enzyme Containing Redox Polymer Networks for Biosensors or Biofuel Cells: A Photochemical Approach
Bunte, C., Prucker, O., König, T. A. F., & Rühe, J. (2009) · Langmuir · doi:10.1021/la9037183 · Cited by 59 · see citing works
Matharu, Z., Enomoto, J., & Revzin, A. (2012) · Analytical Chemistry · doi:10.1021/ac3025619 · Cited by 57 · see citing works
Noninvasive glucose detection in exhaled breath condensate
Tankasala, D., & Linnes, J. C. (2019) · Translational research · doi:10.1016/j.trsl.2019.05.006 · Cited by 54 · see citing works
Singh, D., Tripathi, A., Nayak, V., & Kumar, A. (2011) · Journal of Biomaterials Science Polymer Edition · doi:10.1163/092050610x522486 · Cited by 53 · see citing works
The Fibrotic Response to Implanted Biomaterials: Implications for Tissue Engineering
Rolfe, B. E., Mooney, J. E., Zhang, B., Jahnke, S., Le, S.-J., Chau, Y.-Q., Huang, Q., Wang, H., CAMPBELL, G. R., & Campbell, J. (2011) · InTech eBooks · doi:10.5772/21790 · Cited by 53 · see citing works
Ju, Y. M., Yu, B., West, L., Moussy, Y., & Moussy, F. (2010) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32400 · Cited by 52 · see citing works
Micropatterned Nanocomposite Hydrogels for Biosensing Applications
Pedrosa, V. A., Yan, J., Simonian, A. L., & Revzin, A. (2011) · Electroanalysis · doi:10.1002/elan.201000654 · Cited by 51 · see citing works
Chronic inflammatory responses to microgel‐based implant coatings
Bridges, A. W., Whitmire, R. E., Singh, N., Templeman, K. L., Babensee, J. E., Lyon, L. A., & Garcı́a, A. J. (2010) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32669 · Cited by 51 · see citing works
Wagner, J. G., Schmidtke, D. W., Quinn, C. P., Fleming, T. F., Bernacky, B. J., & Heller, A. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.11.6379 · Cited by 51 · see citing works
Self-citationZhang, W., Zhang, Z., & Wang, X. (2009) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2009.01.058 · Cited by 50 · see citing works
Tissue responses to novel tissue engineering biodegradable cryogel scaffolds: An animal model
Bölgen, N., Vargel, İ., Korkusuz, P., Güzel, E., Plieva, F. M., Galaev, I. Y., Mattìasson, B., & Pişkın, E. (2008) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32193 · Cited by 50 · see citing works
Catalase Effects on Glucose-Sensitive Hydrogels
Jung, D.-Y., Magda, J. J., & Han, I. S. (2000) · Macromolecules · doi:10.1021/ma992098b · Cited by 50 · see citing works
Papadopoulos, A., Bichara, D. A., Zhao, X., Ibusuki, S., Randolph, M. A., Anseth, K. S., & Yaremchuk, M. J. (2010) · Tissue Engineering Part A · doi:10.1089/ten.tea.2010.0253 · Cited by 46 · see citing works
Indispensable Platforms for Bioimmobilization: Maleimide-Based Thiol Reactive Hydrogels
Park, E. J., Gevrek, T. N., Sanyal, R., & Sanyal, A. (2014) · Bioconjugate Chemistry · doi:10.1021/bc500375r · Cited by 46 · see citing works
Titanium surface modification techniques for dental implants—From microscale to nanoscale
Subramani, K., Mathew, R. T., & Pachauri, P. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-812291-4.00006-6 · Cited by 46 · see citing works
Bölgen, N., Yang, Y., Korkusuz, P., Güzel, E., Haj, A. J. E., & Piskin, E. (2010) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.375 · Cited by 44 · see citing works
Sources of instability of ‘wired’ enzyme anodes in serum: urate and transition metal ions
Binyamin, G. N., Chen, T., & Heller, A. (2001) · Journal of Electroanalytical Chemistry · doi:10.1016/s0022-0728(00)00267-9 · Cited by 44 · see citing works
Self-citationBiointerface analysis on a molecular level
Tiefenauer, L., & Ros, R. (2002) · Colloids and Surfaces B Biointerfaces · doi:10.1016/s0927-7765(01)00228-4 · Cited by 42 · see citing works
Lee, W., Choi, D., Kim, J. H., & Koh, W. (2008) · Biomedical Microdevices · doi:10.1007/s10544-008-9196-1 · Cited by 41 · see citing works
Application of responsive polymers in implantable medical devices and biosensors
Li, J., Stachowski, M., & Zhang, Z. (2015) · Elsevier eBooks · doi:10.1016/b978-0-85709-713-2.00011-0 · Cited by 41 · see citing works
Electrochemical biosensors for on-chip detection of oxidative stress from immune cells
Yan, J., Pedrosa, V. A., Enomoto, J., Simonian, A. L., & Revzin, A. (2011) · Biomicrofluidics · doi:10.1063/1.3624739 · Cited by 40 · see citing works
Characterization of Biomaterials by Soft X-Ray Spectromicroscopy
Leung, B. O., Brash, J. L., & Hitchcock, A. P. (2010) · Materials · doi:10.3390/ma3073911 · Cited by 39 · see citing works
Recent Advances in Anti-inflammatory Strategies for Implantable Biosensors and Medical Implants
Lee, D., Park, K., & Seo, J. (2020) · BioChip Journal · doi:10.1007/s13206-020-4105-7 · Cited by 38 · see citing works
Quinn, C. P., Pishko, M. V., Schmidtke, D. W., Ishikawa, M., Wagner, J. G., Raskin, P., Hubbell, J. A., & Heller, A. (1995) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1995.269.1.e155 · Cited by 38 · see citing works
Self-citationJang, E., Park, S., Park, S., Lee, Y., Kim, D., Kim, B., & Koh, W. (2009) · Polymers for Advanced Technologies · doi:10.1002/pat.1455 · Cited by 37 · see citing works
Buckling‐Assisted Patterning of Multiple Polymers
Hyun, D. C., Moon, G. D., Park, C. J., Kim, B. S., Younan Xia, A., & Jeong, U. (2010) · Advanced Materials · doi:10.1002/adma.201000277 · Cited by 37 · see citing works
Anti‐inflammatory properties of micropatterned titanium coatings
Sahlin, H., Contreras, R., Gaskill, D. F., Bjursten, L. M., & Frangos, J. A. (2005) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30642 · Cited by 36 · see citing works
Park, S., Nam, S. H., & Koh, W. (2011) · Journal of Applied Polymer Science · doi:10.1002/app.34532 · Cited by 35 · see citing works
Lee, Y., Kim, D. N., Choi, D., Lee, W., Park, J., & Koh, W. (2008) · Polymers for Advanced Technologies · doi:10.1002/pat.1047 · Cited by 35 · see citing works
Distributed sensor and actuator networks for closed-loop bioelectronic medicine
Bhave, G., Chen, J., Singer, A. L., Sharma, A., & Robinson, J. T. (2021) · Materials Today · doi:10.1016/j.mattod.2020.12.020 · Cited by 34 · see citing works
Yavuz, H., Bayramoğlu, G., Kaçar, Y., Deni̇zli̇, A., & Arica, M. Y. (2002) · Biochemical Engineering Journal · doi:10.1016/s1369-703x(01)00146-2 · Cited by 34 · see citing works
Kolewe, K. W., Kalasin, S., Shave, M. K., Schiffman, J. D., & Santore, M. M. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b18302 · Cited by 33 · see citing works
Lasagni, A. F., Yuan, D., Shao, P., & Das, S. (2009) · Advanced Engineering Materials · doi:10.1002/adem.200800295 · Cited by 33 · see citing works
Bölgen, N., Korkusuz, P., Vargel, İ., Kılıç, E., Güzel, E., Çavuşoğlu, T., Uçkan, D., & Pişkın, E. (2013) · Artificial Cells Nanomedicine and Biotechnology · doi:10.3109/21691401.2013.775578 · Cited by 33 · see citing works
Czuba, U., Quintana, R., Pauw-Gillet, M.-C. D., Bourguignon, M., Moreno-Couranjou, M., Alexandre, M., Detrembleur, C., & Choquet, P. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201701059 · Cited by 26 · see citing works
Material Design in Implantable Biosensors toward Future Personalized Diagnostics and Treatments
Ghorbanizamani, F., Moulahoum, H., Guler, E., & Tımur, S. (2023) · Applied Sciences · doi:10.3390/app13074630 · Cited by 29 · see citing works
Characteristics of Two Self-Powered Glucose Biosensors
Kulkarni, T., & Slaughter, G. E. (2017) · IEEE Sensors Journal · doi:10.1109/jsen.2017.2696260 · Cited by 29 · see citing works
Titanium Surface Modification Techniques for Dental Implants—From Microscale to Nanoscale
Subramani, K., & Mathew, R. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4557-7862-1.00006-7 · Cited by 28 · see citing works
Statistics for Critical Clinical Decision Making Based on Readings of Pairs of Implanted Sensors
Schmidtke, D. W., Pishko, M. V., Quinn, C. P., & Heller, A. (1996) · Analytical Chemistry · doi:10.1021/ac9602027 · Cited by 27 · see citing works
Self-citationRussell, R. J., Sirkar, K., & Pishko, M. V. (2000) · Langmuir · doi:10.1021/la991388i · Cited by 26 · see citing works
Subramani, K., & Birch, M. A. (2006) · Biomedical Materials · doi:10.1088/1748-6041/1/3/009 · Cited by 25 · see citing works
Photoresponsive smart template for reversible cell micropatterning
Gong, Y., Yang, J., Cao, F., Zhang, J., Cheng, H. L., Zhuo, R., & Zhang, X. (2013) · Journal of Materials Chemistry B · doi:10.1039/c3tb20073f · Cited by 25 · see citing works
- Authors
- Quinn, C. P., Pathak, C. P., Heller, A., & Hubbell, J. A.
- Affiliations
- The University of Texas at Austin (US)
- Corresponding author
- Hubbell, Jeffrey A.
- Venue
- Biomaterials
- Publisher
- Elsevier BV
- Published
- 1995-01
- Volume
- 16
- Issue
- 5
- Pages
- 389-396
- ISSN
- 0142-9612 (ISSN-L)
- OpenAlex
- W1988024774
- Cited by
- 172
- References
- 19
- Citations by year
- 2025: 5 · 2023: 2 · 2022: 2 · 2021: 3 · 2020: 2 · 2019: 4 · 2018: 4 · 2017: 4 · 2016: 5 · 2015: 4 · 2014: 8 · 2013: 8 · 2012: 7
- FWCI
- 5.74
- Type
- journal article
- Language
- en
- Open access
- green
- infoscience.epfl.ch
- Locations
- Biomaterials (publishedVersion)
- PubMed (publishedVersion)
- Infoscience (Ecole Polytechnique Fédérale de Lausanne) (submittedVersion)
- Infoscience (Ecole Polytechnique Fédérale de Lausanne) (submittedVersion, cc-by-nc-nd)
- Funders
- National Institutes of Health (5r01dk042015-07)
- National Institute of Diabetes and Digestive and Kidney Diseases (DK42015)
- Topics
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrochemical sensors and biosensors
- Physical Sciences › Materials Science › Surfaces, Coatings and Films › Polymer Surface Interaction Studies
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Keywords
- 2-hydroxyethyl methacrylate, ethylene glycol dimethacrylate, glucose biosensor, biocompatibility, subcutaneous implantation, glucose oxidase, gold electrode, fibrous encapsulation, in situ crosslinking, 2,2-dimethoxy-2-phenylacetophenone
- MeSH terms
- Acrylates, Animals, Biocompatible Materials, Calibration, Cross-Linking Reagents, Glucose, Male, Methacrylates, Photochemistry, Polyethylene Glycols, Polymers, Ultraviolet Rays, Biosensing Techniques, Rats, Sprague-Dawley, Rats
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