Biosensors for real-time in vivo measurements
Abstract
The current status of sensors capable of continuous measurement of analytes in biological media is reviewed. This review containing 173 references deals with devices whose use in single cells, tissue slices, animal models and humans has been demonstrated. In addition to sensors specific for glucose, lactate, glutamate, pyruvate, choline and acetylcholine, insights obtained from monitoring nitric oxide, Na(+), K(+), Ca(2+), and dopamine are presented. Performance criteria for sensor performance are described as is the subject of biosensor calibration. Biocompatibility issues are dealt with in some detail as is the status of continuous blood glucose monitoring in humans.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Electron mediators can reduce the impact of interfering species by lowering the working potential needed to oxidize hydrogen peroxide.
“As described earlier, the use of mediators to shuttle electrons between the enzyme and the electrode can also minimize the impact of interfering species by lowering the working potential required to oxidize hydrogen peroxide.56,58,62”
From Biocompatible Materials for Continuous Glucose Monitoring Devices (2013) · cites this paper as [58]
Cites
(1993) · New England Journal of Medicine · doi:10.1056/nejm199309303291401 · Cited by 24,667 · see citing works
ELECTRODE SYSTEMS FOR CONTINUOUS MONITORING IN CARDIOVASCULAR SURGERY
Clark, L. C., & Lyons, C. (1962) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1962.tb13623.x · Cited by 3,945 · see citing works
HEPATOCELLULAR CARCINOMA AND HEPATITIS B VIRUS
Beasley, R. P., Lin, C., Hwang, L., & Chien, C. (1981) · The Lancet · doi:10.1016/s0140-6736(81)90585-7 · Cited by 2,856 · see citing works
Electrochemical biosensors: recommended definitions and classification
Thévenot, D. R., Tóth, K., Durst, R. A., & Wilson, G. S. (2001) · Biosensors and Bioelectronics · doi:10.1016/s0956-5663(01)00115-4 · Cited by 1,770 · see citing works
Self-citationEvaluating clinical accuracy of systems for self-monitoring of blood glucose
Clarke, W. L., Cox, D., Gonder-Frederick, L. A., Carter, W., & Pohl, S. L. (1987) · Diabetes Care · doi:10.2337/diacare.10.5.622 · Cited by 1,435 · see citing works
Neural activity triggers neuronal oxidative metabolism followed by astrocytic glycolysis
Kasischke, K. A., Vishwasrao, H. D., Fisher, P. J., Zipfel, W. R., & Webb, W. W. (2004) · Science · doi:10.1126/science.1096485 · Cited by 742 · see citing works
Surveying for Surfaces that Resist the Adsorption of Proteins
Chapman, R., Ostuni, E., Takayama, S., Holmlin, R. E., Yan, L., & Whitesides, G. M. (2000) · Journal of the American Chemical Society · doi:10.1021/ja000774f · Cited by 600 · see citing works
Methods for reducing biosensor membrane biofouling
Wisniewski, N., & Reichert, M. (2000) · Colloids and Surfaces B: Biointerfaces · doi:10.1016/s0927-7765(99)00148-4 · Cited by 543 · see citing works
The Encyclopedia of Electrochemistry
(1965) · Students Quarterly Journal · doi:10.1049/sqj.1965.0065 · Cited by 501 · see citing works
Daunert, S., Barrett, G., Feliciano, J. S., Shetty, R. S., Shrestha, S., & Smith‐Spencer, W. (2000) · Chemical Reviews · doi:10.1021/cr990115p · Cited by 446 · see citing works
Enzyme-Based Biosensors for in Vivo Measurements
Wilson, G. S., & Hu, Y. (2000) · Chemical Reviews · doi:10.1021/cr990003y · Cited by 434 · see citing works
Self-citationAntioxidant defense of the brain: a role for astrocytes
Wilson, J. X. (1997) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y97-146 · Cited by 430 · see citing works
Psychoanalytical Electrochemistry: Dopamine and Behavior
Venton, B. J., & Wightman, R. M. (2003) · Analytical Chemistry · doi:10.1021/ac031421c · Cited by 423 · see citing works
The MiniMed Continuous Glucose Monitoring System
Mastrototaro, J. J. (2000) · Diabetes Technology & Therapeutics · doi:10.1089/15209150050214078 · Cited by 393 · see citing works
Development and Application of Cell-Based Biosensors
Pancrazio, J. J., Whelan, J., Borkholder, D. A., Ma, W., & Stenger, D. A. (1999) · Annals of Biomedical Engineering · doi:10.1114/1.225 · Cited by 391 · see citing works
Tierney, M. J., Tamada, J. A., Potts, R. O., Jovanovic, L., & Garg, S. (2001) · Biosensors and Bioelectronics · doi:10.1016/s0956-5663(01)00189-0 · Cited by 390 · see citing works
Rebrin, K., Steil, G. M., van Antwerp, W. P., & Mastrototaro, J. J. (1999) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1999.277.3.e561 · Cited by 367 · see citing works
Subsecond Adsorption and Desorption of Dopamine at Carbon-Fiber Microelectrodes
Bath, B. D., Michael, D. J., Venton, B. J., Joseph, J. D., Runnels, P. L., & Wightman, R. M. (2000) · Analytical Chemistry · doi:10.1021/ac000849y · Cited by 363 · see citing works
Characterization of implantable biosensor membrane biofouling
Wisniewski, N. A., Moussy, F. G., & Reichert, W. M. (2000) · Fresenius Journal of Analytical Chemistry · doi:10.1007/s002160051556 · Cited by 351 · see citing works
Hu, Y., & Wilson, G. S. (1997) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1997.69041484.x · Cited by 337 · see citing works
Self-citationChapter 4 Mechanisms of inflammation and infection with implanted devices
Anderson, J. M. (1993) · Cardiovascular Pathology · doi:10.1016/1054-8807(93)90045-4 · Cited by 331 · see citing works
WEARABLE ARTIFICIAL ENDOCRINE PANCREAS WITH NEEDLE-TYPE GLUCOSE SENSOR
Shichiri, M., Yamasaki, Y., Kawamori, R., Hakui, N., & Abe, H. (1982) · The Lancet · doi:10.1016/s0140-6736(82)92788-x · Cited by 314 · see citing works
Evaluating the Accuracy of Continuous Glucose-Monitoring Sensors
Kovatchev, B. P., Gonder-Frederick, L. A., Cox, D. J., & Clarke, W. L. (2004) · Diabetes Care · doi:10.2337/diacare.27.8.1922 · Cited by 312 · see citing works
Closed-loop insulin delivery—the path to physiological glucose control
Steil, G. M. (2003) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2003.08.011 · Cited by 310 · see citing works
Surface modification of polymers: chemical, biological and surface analytical challenges
Ratner, B. D. (1995) · Biosensors and Bioelectronics · doi:10.1016/0956-5663(95)99218-a · Cited by 304 · see citing works
Burmeister, J. J., & Gerhardt, G. A. (2001) · Analytical Chemistry · doi:10.1021/ac0010429 · Cited by 289 · see citing works
Noninvasive Glucose Monitoring
Tamada, J. A., Garg, S. K., Jovanovič, L., Pitzer, K. R., Fermi, S. J., & Potts, R. O. (1999) · JAMA · doi:10.1001/jama.282.19.1839 · Cited by 281 · see citing works
Aptamer-based biosensor arrays for detection and quantification of biological macromolecules
McCauley, T. G., Hamaguchi, N., & Stanton, M. J. (2003) · Analytical Biochemistry · doi:10.1016/s0003-2697(03)00297-5 · Cited by 266 · see citing works
o-Phenylenediamine-Modified Carbon Fiber Electrodes for the Detection of Nitric Oxide
Friedemann, M. N., Robinson, S. W., & Gerhardt, G. A. (1996) · Analytical Chemistry · doi:10.1021/ac960093w · Cited by 266 · see citing works
Hu, Y., Mitchell, K. M., Albahadily, F., Michaelis, E. K., & Wilson, G. S. (1994) · Brain Research · doi:10.1016/0006-8993(94)90870-2 · Cited by 252 · see citing works
Self-citationPhysiological Differences Between Interstitial Glucose and Blood Glucose Measured in Human Subjects
Kulcu, E., Tamada, J. A., Reach, G., Potts, R. O., & Lesho, M. J. (2003) · Diabetes Care · doi:10.2337/diacare.26.8.2405 · Cited by 252 · see citing works
Optical biosensors : present and future
Ligler, F. S., & Taitt, C. A. R. (2002) · Cited by 241 · see citing works
Long-term engraftment of hepatocytes transplanted on biodegradable polymer sponges
Mooney, D. J., Sano, K., Kaufmann, P. M., Majahod, K., Schloo, B. L., Vacanti, J. P., & Langer, R. (1997) · Journal of Biomedical Materials Research · doi:10.1002/(sici)1097-4636(19971205)37:3 · Cited by 233 · see citing works
Kulagina, N. V., Shankar, L., & Michael, A. C. (1999) · Analytical Chemistry · doi:10.1021/ac990636c · Cited by 230 · see citing works
Two-dimensional enzyme electrode sensor for glucose
Gough, D., Lucisano, J. Y., & Tse, P. H. S. (1985) · Analytical Chemistry · doi:10.1021/ac00289a042 · Cited by 223 · see citing works
Hickey, T., Kreutzer, D. L., Burgess, D. J., & Moussy, F. G. (2002) · Journal of Biomedical Materials Research · doi:10.1002/jbm.10016 · Cited by 187 · see citing works
Aussedat, B., Dupire-Angel, M., Gifford, R., Klein, J. C., Wilson, G. S., & Reach, G. (2000) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2000.278.4.e716 · Cited by 186 · see citing works
Self-citationRapid Changes in Local Extracellular Rat Brain Glucose Observed with an In Vivo Glucose Sensor
Hu, Y., & Wilson, G. S. (1997) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1997.68041745.x · Cited by 186 · see citing works
Self-citationFeldman, B., Brazg, R., Schwartz, S. L., & Weinstein, R. L. (2003) · Diabetes Technology & Therapeutics · doi:10.1089/152091503322526978 · Cited by 184 · see citing works
Lowry, J. P., McAteer, K., Atrash, S. S. E., Duff, A., & O'Neill, R. D. (1994) · Analytical Chemistry · doi:10.1021/ac00082a025 · Cited by 183 · see citing works
Emerging biomedical sensing technologies and their applications
Cote, G. L., Lec, R. M., & Pishko, M. V. (2003) · IEEE Sensors Journal · doi:10.1109/jsen.2003.814656 · Cited by 183 · see citing works
An ultrastructural analysis of tissue surrounding a microdialysis probe
Clapp-Lilly, K. L., Roberts, R. C., Duffy, L. K., Irons, K. P., Hu, Y. S., & Drew, K. L. (1999) · Journal of Neuroscience Methods · doi:10.1016/s0165-0270(99)00064-3 · Cited by 181 · see citing works
<i>In vivo</i> leukocyte cytokine mRNA responses to biomaterials are dependent on surface chemistry
Brodbeck, W. G., Voskerician, G., Ziats, N. P., Nakayama, Y., Matsuda, T., & Anderson, J. M. (2003) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.10425 · Cited by 181 · see citing works
Response Times of Carbon Fiber Microelectrodes to Dynamic Changes in Catecholamine Concentration
Venton, B. J., Troyer, K. P., & Wightman, R. M. (2001) · Analytical Chemistry · doi:10.1021/ac010819a · Cited by 178 · see citing works
Bungay, P. M., Newton‐Vinson, P., Isele, W., Garris, P. A., & Justice, J. B. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01904.x · Cited by 173 · see citing works
Quinn, C. P., Pathak, C. P., Heller, A., & Hubbell, J. A. (1995) · Biomaterials · doi:10.1016/0142-9612(95)98856-9 · Cited by 172 · see citing works
Stability of Oxidases Immobilized in Silica Gels
Chen, Q., Kenausis, G. L., & Heller, A. (1998) · Journal of the American Chemical Society · doi:10.1021/ja971750k · Cited by 168 · see citing works
Smith, P. J., Hammar, K. M., Porterfield, D. M., Sanger, R. H., & Trimarchi, J. R. (1999) · Microscopy Research and Technique · doi:10.1002/(sici)1097-0029(19990915)46:6 · Cited by 157 · see citing works
Avshalumov, M. V., Chen, B. T., Marshall, S. P., Peña, D. M., & Rice, M. E. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-07-02744.2003 · Cited by 156 · see citing works
Acetylcholine and Choline Amperometric Enzyme Sensors Characterized in Vitro and in Vivo
Mitchell, K. M. (2004) · Analytical Chemistry · doi:10.1021/ac034757v · Cited by 151 · see citing works
Fluorescent nano-PEBBLE sensors designed for intracellular glucose imaging
Xu, H., Aylott, J. W., & Kopelman, R. R. (2002) · The Analyst · doi:10.1039/b202782h · Cited by 145 · see citing works
A subcutaneous glucose sensor with improved longevity, dynamic range, and stability of calibration.
Updike, S. J., Shults, M. C., Gilligan, B. J., & Rhodes, R. K. (2000) · Diabetes Care · doi:10.2337/diacare.23.2.208 · Cited by 135 · see citing works
von Recum, A. F. (1986) · Medical Entomology and Zoology · Cited by 134 · see citing works
Biosensors: new approaches in drug discovery
Keusgen, M. (2002) · Die Naturwissenschaften · doi:10.1007/s00114-002-0358-3 · Cited by 134 · see citing works
Optical Imaging Fiber-Based Single Live Cell Arrays: A High-Density Cell Assay Platform
Biran, I., & Walt, D. R. (2002) · Analytical Chemistry · doi:10.1021/ac020009e · Cited by 132 · see citing works
Performance of subcutaneously implanted glucose sensors for continuous monitoring
Gerritsen, M. (1999) · The Netherlands Journal of Medicine · doi:10.1016/s0300-2977(99)00006-6 · Cited by 122 · see citing works
Wisniewski, N., Klitzman, B. M., Miller, B., & Reichert, W. M. (2001) · Journal of Biomedical Materials Research · doi:10.1002/1097-4636(20011215)57:4 · Cited by 120 · see citing works
Chen, X., Matsumoto, N., Hu, Y., & Wilson, G. S. (2002) · Analytical Chemistry · doi:10.1021/ac015628m · Cited by 120 · see citing works
Self-citationEklund, S. E., Taylor, D. E., Kozlov, E., Prokop, A., & Cliffel, D. E. (2003) · Analytical Chemistry · doi:10.1021/ac034641z · Cited by 119 · see citing works
A model for biocompatibility and its evaluation
Williams, D. F. (1989) · Journal of Biomedical Engineering · doi:10.1016/0141-5425(89)90138-6 · Cited by 119 · see citing works
Kennedy, R. T., Thompson, J. E., & Vickroy, T. W. (2002) · Journal of Neuroscience Methods · doi:10.1016/s0165-0270(01)00506-4 · Cited by 118 · see citing works
Pellerin, L., & Magistretti, P. J. (2004) · Science · doi:10.1126/science.1100428 · Cited by 115 · see citing works
Dempsey, E., Diamond, D., Smyth, M. R., Urban, G. A., Jobst, G., Moser, I., Verpoorte, E. M. J., Manz, A., Widmer, H. M., Rabenstein, K., et al. (1997) · Analytica Chimica Acta · doi:10.1016/s0003-2670(97)90075-1 · Cited by 112 · see citing works
Critical guidelines for validation of the selectivity of in-vivo chemical microsensors
Phillips, P. E. M., & Wightman, R. M. (2003) · TrAC Trends in Analytical Chemistry · doi:10.1016/s0165-9936(03)00907-5 · Cited by 110 · see citing works
Sharkawy, A. A., Klitzman, B. M., Truskey, G. A., & Reichert, W. M. (1998) · Journal of Biomedical Materials Research · doi:10.1002/(sici)1097-4636(19980615)40:4 · Cited by 110 · see citing works
Lowry, J. P., Miele, M., O'Neill, R. D., Boutelle, M. G., & Fillenz, M. (1998) · Journal of Neuroscience Methods · doi:10.1016/s0165-0270(97)00171-4 · Cited by 109 · see citing works
Efficacy and Reliability of the Continuous Glucose Monitoring System
Gross, T. M., & Mastrototaro, J. J. (2000) · Diabetes Technology & Therapeutics · doi:10.1089/15209150050214087 · Cited by 108 · see citing works
Lowry, J. P., O'Neill, R. D., Boutelle, M. G., & Fillenz, M. (1998) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1998.70010391.x · Cited by 105 · see citing works
Determination of Plasma Glucose During Rapid Glucose Excursions with a Subcutaneous Glucose Sensor
Steil, G. M., Rebrin, K., Mastrototaro, J. J., Bernaba, B., & Saad, M. F. (2003) · Diabetes Technology & Therapeutics · doi:10.1089/152091503763816436 · Cited by 104 · see citing works
Poscia, A., Mascini, M., Moscone, D., Luzzana, M., Caramenti, G., Cremonesi, P., Valgimigli, F., Bongiovanni, C., & Varalli, M. (2003) · Biosensors and Bioelectronics · doi:10.1016/s0956-5663(02)00216-6 · Cited by 101 · see citing works
Taylor, C., Kenausis, G., Katakis, I., & Heller, A. (1995) · Journal of Electroanalytical Chemistry · doi:10.1016/0022-0728(95)04080-8 · Cited by 100 · see citing works
Metabolic Oscillations in β-Cells
Kennedy, R., Kauri, L., Dahlgren, G. M., & Jung, S.-K. (2002) · Diabetes · doi:10.2337/diabetes.51.2007.s152 · Cited by 100 · see citing works
Zeng, G., Gao, L., Birklé, S., & Yu, R. K. (2000) · PubMed · Cited by 98 · see citing works
Mediation of <i>in vivo</i> glucose sensor inflammatory response via nitric oxide release
Gifford, R., Batchelor, M. M., Lee, Y., Gokulrangan, G., Meyerhoff, M. E., & Wilson, G. S. (2005) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30359 · Cited by 96 · see citing works
Self-citationGlucose microbiosensor based on alumina sol–gel matrix/electropolymerized composite membrane
Chen, X., Hu, Y., & Wilson, G. S. (2002) · Biosensors and Bioelectronics · doi:10.1016/s0956-5663(02)00093-3 · Cited by 95 · see citing works
Self-citationPoitout, V., Moatti-Sirat, D., Reach, G., Zhang, Y., Wilson, G. S., Lemonnier, F., & Klein, J. C. (1993) · Diabetologia · doi:10.1007/bf00404077 · Cited by 95 · see citing works
Self-citationMao, L., Osborne, P. G., Yamamoto, K., & Kato, T. (2002) · Analytical Chemistry · doi:10.1021/ac011261+ · Cited by 93 · see citing works
Zhang, Y., & Wilson, G. S. (1993) · Analytica Chimica Acta · doi:10.1016/0003-2670(93)85009-9 · Cited by 92 · see citing works
Self-citationDirect electrochemical measurement of nitric oxide in vascular endothelium
Brovkovych, V. M., Stolarczyk, E. I., Oman, J., Tomboulian, P., & Maliñski, T. (1999) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/s0731-7085(98)00090-9 · Cited by 92 · see citing works
[Measuring EEG complexity for studying the state of mental load].
Liu, J., He, T., Zheng, C., & Huang, Y. (1997) · PubMed · Cited by 91 · see citing works
Fabrication and Characterization of Sputtered-Carbon Microelectrode Arrays
Sreenivas, G., Ang, S. S., Fritsch, I., Brown, W. D., Gerhardt, G. A., & Woodward, D. J. (1996) · Analytical Chemistry · doi:10.1021/ac9508816 · Cited by 89 · see citing works
Influence of inflammatory cells and serum on the performance of implantable glucose sensors
Gerritsen, M., Jansen, J. A., Kros, A., Vriezema, D. M., Sommerdijk, N. A. J. M., Nolte, R. J. M., Lutterman, J. A., van Hövell, S. W. F. M., & van der Gaag, A. (2000) · Journal of Biomedical Materials Research · doi:10.1002/1097-4636(200101)54:1 · Cited by 89 · see citing works
Revzin, A., Sirkar, K., Simonian, A. L., & Pishko, M. V. (2002) · Sensors and Actuators B Chemical · doi:10.1016/s0925-4005(01)00982-0 · Cited by 88 · see citing works
Heller, J., & Heller, A. (1998) · Journal of the American Chemical Society · doi:10.1021/ja973911q · Cited by 88 · see citing works
Invasive consequences of using micro-electrodes and microdialysis probes in the brain
Khan, A. S., & Michael, A. C. (2003) · TrAC Trends in Analytical Chemistry · doi:10.1016/s0165-9936(03)00908-7 · Cited by 86 · see citing works
Optimization of the Geometry and Porosity of Microelectrode Arrays for Sensor Design
Sandison, M. E., Anicet, N., Glidle, A., & Cooper, J. M. (2002) · Analytical Chemistry · doi:10.1021/ac025649w · Cited by 86 · see citing works
Neurochemistry and electroanalytical probes
Troyer, K. P., Heien, M. L., Venton, B. J., & Wightman, R. M. (2002) · Current Opinion in Chemical Biology · doi:10.1016/s1367-5931(02)00374-5 · Cited by 83 · see citing works
Udipi, K., Ornberg, R., Thurmond, K. B., Settle, S. L., Forster, D., & Riley, D. P. (2000) · Journal of Biomedical Materials Research · doi:10.1002/1097-4636(20000915)51:4 · Cited by 82 · see citing works
Subcutaneous glucose monitoring by means of electrochemical sensors: fiction or reality?
Rebrin, K., Fischer, U., von Dorsche, H. H., von Woetke, T., Abel, P., & Brunstein, E. (1992) · Journal of Biomedical Engineering · doi:10.1016/0141-5425(92)90033-h · Cited by 81 · see citing works
Healing of segmental bone defects in rats induced by a ?-TCP-MCPM cement combined with rhBMP-2
Ohura, K., Hamanishi, C., Tanaka, S., & Matsuda, N. (1999) · Journal of Biomedical Materials Research · doi:10.1002/(sici)1097-4636(199902)44:2 · Cited by 77 · see citing works
Calibration of a subcutaneous amperometric glucose sensor implanted for 7 days in diabetic patients
Choleau, C., Klein, J. C., Reach, G., Aussedat, B., Demaria-Pesce, V., Wilson, G. S., Gifford, R., & Ward, W. K. (2002) · Biosensors and Bioelectronics · doi:10.1016/s0956-5663(01)00304-9 · Cited by 76 · see citing works
Self-citationKerner, W., Kiwit, M., Linke, B., Keck, F. S., Zier, H., & Pfeiffer, E. F. (1993) · Biosensors and Bioelectronics · doi:10.1016/0956-5663(93)80032-k · Cited by 75 · see citing works
Simultaneous detection of diverse analytes with an aptazyme ligase array
Hesselberth, J. R., Robertson, M. P., Knudsen, S. M., & Ellington, A. D. (2003) · Analytical Biochemistry · doi:10.1016/s0003-2697(02)00441-4 · Cited by 75 · see citing works
Ceramic-based multisite microelectrode array for rapid choline measures in brain tissue
Burmeister, J. J., Palmer, M. R., & Gerhardt, G. A. (2003) · Analytica Chimica Acta · doi:10.1016/s0003-2670(03)00067-9 · Cited by 74 · see citing works
In vitro and in vivo mineralization of Nafion membrane used for implantable glucose sensors
Mercado, R. C., & Moussy, F. (1998) · Biosensors and Bioelectronics · doi:10.1016/s0956-5663(97)00112-7 · Cited by 73 · see citing works
Nitric Oxide-Releasing Sol−Gel Particle/Polyurethane Glucose Biosensors
Shin, J. H., Marxer, S. M., & Schoenfisch, M. H. (2004) · Analytical Chemistry · doi:10.1021/ac049776z · Cited by 71 · see citing works
Direct, Real-Time Sensing of Free Radical Production by Activated Human Glioblastoma Cells
Manning, P., McNeil, C. J., Cooper, J. M., & Hillhouse, E. W. (1998) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(97)00455-3 · Cited by 69 · see citing works
Operation of a Miniature Redox Hydrogel-Based Pyruvate Sensor in Undiluted Deoxygenated Calf Serum
Gajovic, N., Binyamin, G. N., Warsinke, A., Scheller, F. W., & Heller, A. (2000) · Analytical Chemistry · doi:10.1021/ac991021i · Cited by 66 · see citing works
Schmidtke, D. W., & Heller, A. (1998) · Analytical Chemistry · doi:10.1021/ac970932u · Cited by 65 · see citing works
Fundamental Studies of Glucose Oxidase Deposition on a Pt Electrode
Matsumoto, N., Chen, X., & Wilson, G. S. (2001) · Analytical Chemistry · doi:10.1021/ac015536x · Cited by 65 · see citing works
Self-citationIn Vitro and In Vivo Degradation of Glucose Oxidase Enzyme Used for an Implantable Glucose Biosensor
Valdes, T. I., & Moussy, F. G. (2000) · Diabetes Technology & Therapeutics · doi:10.1089/15209150050194233 · Cited by 64 · see citing works
A Pyruvate Oxidase Electrode Based on an Electrochemically Deposited Redox Polymer
Gajovic, N., Habermüller, K., Warsinke, A., Schuhmann, W. W., & Scheller, F. W. (1999) · Electroanalysis · doi:10.1002/(sici)1521-4109(199912)11:18 · Cited by 63 · see citing works
Fabre, B., Burlet, S., Cespuglio, R., & Bidan, G. (1997) · Journal of Electroanalytical Chemistry · doi:10.1016/s0022-0728(96)04985-6 · Cited by 63 · see citing works
Small-Volume On-Line Sensor for Continuous Measurement of γ-Aminobutyric Acid
Niwa, O., Kurita, R., Horiuchi, T., & Torimitsu, K. (1998) · Analytical Chemistry · doi:10.1021/ac970740z · Cited by 63 · see citing works
Galeska, I., Hickey, T., Moussy, F. G., Kreutzer, D. L., & Papadimitrakopoulos, F. (2001) · Biomacromolecules · doi:10.1021/bm010112y · Cited by 62 · see citing works
Calibration of a subcutaneous amperometric glucose sensor
Choleau, C., Klein, J. C., Reach, G., Aussedat, B., Demaria-Pesce, V. H., Wilson, G. S., Gifford, R., & Ward, W. K. (2002) · Biosensors and Bioelectronics · doi:10.1016/s0956-5663(01)00306-2 · Cited by 60 · see citing works
Self-citationShram, N. F., Netchiporouk, L. I., & Cespuglio, R. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.02081.x · Cited by 60 · see citing works
Lowry, J., & Fillenz, M. (2001) · Bioelectrochemistry · doi:10.1016/s1567-5394(01)00109-8 · Cited by 59 · see citing works
Microdialysis of Glucose in Subcutaneous Adipose Tissue up to 3 Weeks in Healthy Volunteers
Wientjes, K. J. C., Vonk, P., Klei, Y. V.-V., Schoonen, A. J. M., & Kossen, N. W. F. (1998) · Diabetes Care · doi:10.2337/diacare.21.9.1481 · Cited by 58 · see citing works
Enzymatic glucose sensors. Improved long-term performance in vitro and in vivo.
Updike, S. J., Shults, M. C., Rhodes, R. K., GILLIGAN, B. J., LUEBOW, J. O., & von Heimburg, D. (1994) · PubMed · Cited by 57 · see citing works
Preparation and characterization of implantable sensors with nitric oxide release coatings
Frost, M. C., Batchelor, M. M., Lee, Y.-M., Zhang, H., Kang, Y., Oh, B. K., Wilson, G. S., Gifford, R., Rudich, S. M., & Meyerhoff, M. E. (2003) · Microchemical Journal · doi:10.1016/s0026-265x(03)00033-x · Cited by 55 · see citing works
Self-citationResolving dynamic changes in brain metabolism using biosensors and on-line microdialysis
Parkin, M. C., Hopwood, S. E., Boutelle, M. G., & Strong, A. J. (2003) · TrAC Trends in Analytical Chemistry · doi:10.1016/s0165-9936(03)00912-9 · Cited by 53 · see citing works
Updike, S. J., Shults, M. C., Rhodes, R. K., GILLIGAN, B. J., LUEBOW, J. O., & von Heimburg, D. (1994) · ASAIO Journal · doi:10.1097/00002480-199404000-00007 · Cited by 52 · see citing works
A Theoretical Description of Microdialysis with Mass Transport Coupled to Chemical Events
Yang, H., Peters, J. L., Allen, C., Chern, S.-S., Coalson, R. D., & Michael, A. C. (2000) · Analytical Chemistry · doi:10.1021/ac991186r · Cited by 51 · see citing works
Glucose sensor with improved haemocompatibilty
Yang, Y. (2000) · Biosensors and Bioelectronics · doi:10.1016/s0956-5663(00)00082-8 · Cited by 49 · see citing works
Kahlert, S., & Reiser, G. (2004) · Cell Calcium · doi:10.1016/j.ceca.2004.02.009 · Cited by 48 · see citing works
McAteer, K., & O'Neill, R. D. (1996) · The Analyst · doi:10.1039/an9962100773 · Cited by 47 · see citing works
Brown, F. O., & Lowry, J. (2003) · The Analyst · doi:10.1039/b300266g · Cited by 45 · see citing works
Sources of instability of ‘wired’ enzyme anodes in serum: urate and transition metal ions
Binyamin, G. N., Chen, T., & Heller, A. (2001) · Journal of Electroanalytical Chemistry · doi:10.1016/s0022-0728(00)00267-9 · Cited by 44 · see citing works
Varalli, M., Marelli, G., Maran, A., Bistoni, S., Luzzana, M., Cremonesi, P., Caramenti, G., Valgimigli, F., & Poscia, A. (2003) · Biosensors and Bioelectronics · doi:10.1016/s0956-5663(02)00215-4 · Cited by 44 · see citing works
Modification of the sensitivity of glucose sensor implanted into subcutaneous tissue.
Thomé-Duret, V., Gangnerau, M.-N., Zhang, Y., Wilson, G. S., & Reach, G. (1996) · PubMed · Cited by 42 · see citing works
Self-citationHealey, B. G., & Walt, D. R. (1997) · Analytical Chemistry · doi:10.1021/ac961058s · Cited by 42 · see citing works
Lutgers, H. L. (2000) · The Netherlands Journal of Medicine · doi:10.1016/s0300-2977(00)00022-x · Cited by 42 · see citing works
More Biocompatible Electrochemical Sensors Using Nitric Oxide Release Polymers
Mowery, K. A., Schoenfisch, M. H., Baliga, N., Wahr, J. A., & Meyerhoff, M. E. (1999) · Electroanalysis · doi:10.1002/(sici)1521-4109(199907)11:10/11 · Cited by 42 · see citing works
Prevention of Hypoglycemia Using Risk Assessment With a Continuous Glucose Monitoring System
Choleau, C., Dokládal, P., Klein, J. C., Ward, W. K., Wilson, G. S., & Reach, G. (2002) · Diabetes · doi:10.2337/diabetes.51.11.3263 · Cited by 42 · see citing works
Self-citationLiu, Z., Niwa, O., Horiuchi, T., Kurita, R., & Torimitsu, K. (1999) · Biosensors and Bioelectronics · doi:10.1016/s0956-5663(99)00041-x · Cited by 41 · see citing works
Lowry, J., Ryan, M. R., & O'Neill, R. D. (1998) · Analytical Communications · doi:10.1039/a708747k · Cited by 40 · see citing works
Cui, J., Kulagina, N. V., & Michael, A. C. (2001) · Journal of Neuroscience Methods · doi:10.1016/s0165-0270(00)00343-5 · Cited by 39 · see citing works
Real-time multisite observation of glutamate release in rat hippocampal slices
Kasai, N., Jimbo, Y., Niwa, O., Matsue, T., & Torimitsu, K. (2001) · Neuroscience Letters · doi:10.1016/s0304-3940(01)01763-3 · Cited by 38 · see citing works
Development and comparison of biosensors for in-vivo applications
Georganopoulou, D. G., Carley, R., JONES, D. A., & Boutelle, M. G. (2000) · Faraday Discussions · doi:10.1039/b003256p · Cited by 38 · see citing works
Gramsbergen, J. B., Leegsma‐Vogt, G., Venema, K., Noraberg, J., & Korf, J. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01673.x · Cited by 37 · see citing works
Yao, T., Yano, T., & Nishino, H. (2004) · Analytica Chimica Acta · doi:10.1016/j.aca.2003.12.062 · Cited by 36 · see citing works
Lowry, J., Demestre, M., & Fillenz, M. (1998) · Developmental Neuroscience · doi:10.1159/000017298 · Cited by 34 · see citing works
Nitric oxide and oxygen metabolism
Brown, G. C., McBride, A. G., Fox, E. J., McNaught, K. S. P., & Borutaitė, V. (1997) · Biochemical Society Transactions · doi:10.1042/bst0250901 · Cited by 34 · see citing works
The Use of Optical Fiber Bundles Combined with Electrochemistry for Chemical Imaging
Szunerits, S., & Walt, D. R. (2003) · ChemPhysChem · doi:10.1002/cphc.200390029 · Cited by 30 · see citing works
Stability of immobilized enzymes as biosensors for continuous application in vitro and in vivo
Abel, P., von Woedtke, T., Schulz, B., Bergann, T., & Schwock, A. (1999) · Journal of Molecular Catalysis B Enzymatic · doi:10.1016/s1381-1177(99)00024-7 · Cited by 29 · see citing works
Surface chemistry control of monocyte and macrophage adhesion, morphology, and fusion
Collier, T. O., Thomas, C. H., Anderson, J. M., & Healy, K. E. (2000) · Journal of Biomedical Materials Research · doi:10.1002/(sici)1097-4636(200001)49:1 · Cited by 29 · see citing works
An independently addressable microbiosensor array: What are the limits of sensing element density?
Yu, P., & Wilson, G. S. (2000) · Faraday Discussions · doi:10.1039/b001611j · Cited by 29 · see citing works
Self-citationIn vivo calibration of the subcutaneous amperometric glucose sensors using a non-enzyme electrode
Jeong, R.-A., Hwang, J. Y., Joo, S., Chung, T. D., Park, S., Kang, S. K., Lee, W., & Kim, H. C. (2003) · Biosensors and Bioelectronics · doi:10.1016/s0956-5663(03)00219-7 · Cited by 28 · see citing works
Statistics for Critical Clinical Decision Making Based on Readings of Pairs of Implanted Sensors
Schmidtke, D. W., Pishko, M. V., Quinn, C. P., & Heller, A. (1996) · Analytical Chemistry · doi:10.1021/ac9602027 · Cited by 27 · see citing works
Novel Hyaluronic Acid Coating for Potential Use in Glucose Sensor Design
Praveen, S., Hanumantha, R., Belovich, J., & Davis, B. L. (2003) · Diabetes Technology & Therapeutics · doi:10.1089/152091503765691893 · Cited by 26 · see citing works
Microfabrication technology of flexible membrane based sensors for in vivo applications
Buck, R. P., Coșofreţ, V. V., Lindner, E., Ufer, S., Mudaras, M. B., Johnson, T. A., Ash, R. B., & Neumun, M. R. (1995) · Electroanalysis · doi:10.1002/elan.1140070910 · Cited by 26 · see citing works
Localized Exocytosis Detected by Spatially Resolved Amperometry in Single Pancreatic β-Cells
Paras, C. D., Qian, W., Lakey, J. R. T., Tan, W., & Kennedy, R. T. (2000) · Cell Biochemistry and Biophysics · doi:10.1385/cbb:33:3:227 · Cited by 25 · see citing works
A Wire-Based Dual-Analyte Sensor for Glucose and Lactate: In Vitro and In Vivo Evaluation
Ward, W. K., House, J. L., Birck, J., Anderson, E. M., & Jansen, L. B. (2004) · Diabetes Technology & Therapeutics · doi:10.1089/152091504774198106 · Cited by 25 · see citing works
A Model for Transport of Glucose in Adipose Tissue to a Microdialysis Probe
Schoonen, A. J. M., & Wientjes, K. J. C. (2003) · Diabetes Technology & Therapeutics · doi:10.1089/152091503322250604 · Cited by 25 · see citing works
Rigby, G., Ahmed, S., Horseman, G., & Vadgama, P. M. (1999) · Analytica Chimica Acta · doi:10.1016/s0003-2670(98)00665-5 · Cited by 25 · see citing works
Simulations of the Frequency Response of Implantable Glucose Sensors
Jablecki, M., & Gough, D. A. (2000) · Analytical Chemistry · doi:10.1021/ac991018z · Cited by 24 · see citing works
Principles of Sensorial Radical Detection-A Minireview
Lisdat, F., & Scheller, F. W. (2000) · Analytical Letters · doi:10.1080/00032710008543032 · Cited by 24 · see citing works
Glucose uptake and flux through phosphofructokinase in wounded rat skeletal muscle
Förster, J., Morris, A. S., Shearer, J. D., Mastrofrancesco, B., Inman, K. C., Lawler, R. G., Bowen, W. D., & Caldwell, M. D. (1989) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1989.256.6.e788 · Cited by 24 · see citing works
Ultrafiltration of human serum to determine the size of species that poison voltammetric electrodes
Elbicki, J. M., & Weber, S. G. (1989) · Biosensors · doi:10.1016/0265-928x(89)80039-2 · Cited by 24 · see citing works
Meyerhoff, C., Mennel, F. J., Bischof, F., Sternberg, F., & Pfeiffer, E. F. (1994) · Hormone and Metabolic Research · doi:10.1055/s-2007-1001752 · Cited by 23 · see citing works
Huang, T. H., Warsinke, A., Koroljova-Skorobogatko, O. V., Makower, A., Kuwana, T., & Scheller, F. W. (1999) · Electroanalysis · doi:10.1002/(sici)1521-4109(199905)11:5 · Cited by 23 · see citing works
Yang, D., Tsai, T., Cheng, C.-H., Lee, C.-W., Chen, S.-H., & Cheng, F.-C. (2001) · Journal of Chromatography A · doi:10.1016/s0021-9673(00)01033-5 · Cited by 22 · see citing works
Oxygen tension at the subcutaneous implantation site of glucose sensors.
Fischer, U., Hidde, A., Herrmann, S., von Woedtke, T., Rebrin, K., & Abel, P. (1989) · PubMed · Cited by 22 · see citing works
Direct measurement of glucose gradients and mass transport within islets of Langerhans
Kauri, L. M., Jung, S., & Kennedy, R. T. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)00595-3 · Cited by 21 · see citing works
The Role of the Independent Variable to Glucose Sensor Calibration
Panteleon, A. E., Rebrin, K., & Steil, G. M. (2003) · Diabetes Technology & Therapeutics · doi:10.1089/152091503765691901 · Cited by 20 · see citing works
Implantable glucose sensor: progress and problems
Moussy, F. G. (2003) · Proceedings of IEEE Sensors/Proceedings of IEEE Sensors ... · doi:10.1109/icsens.2002.1037097 · Cited by 19 · see citing works
Biomaterials Community Examines Biosensor Biocompatibility
Moussy, F. G., & Reichert, W. M. (2000) · Diabetes Technology & Therapeutics · doi:10.1089/15209150050194341 · Cited by 18 · see citing works
Analysis of chemical dynamics in microenvironments
Wightman, R. M., Runnels, P. L., & Troyer, K. P. (1999) · Analytica Chimica Acta · doi:10.1016/s0003-2670(99)00605-4 · Cited by 16 · see citing works
Mediated Electron‐transfer between Redox‐enzymes and Electrode Supports
Katz, E. Y., Shipway, A. N., & Willner, I. (2002) · Encyclopedia of Electrochemistry · doi:10.1002/9783527610426.bard090017 · Cited by 12 · see citing works
New technologies for amperometric biosensors
Boutelle, M. G., Allen, H., Hill, O., Berners, M. O. M., John, R., Dobson, P. D., & Leigh, P. J. (1996) · Journal of Molecular Recognition · doi:10.1002/(sici)1099-1352(199634/12)9:5/6 · Cited by 10 · see citing works
Direct biologically based biosensing of dynamic physiological function
Christini, D. J., Walden, J., & Edelberg, J. M. (2001) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.2001.280.5.h2006 · Cited by 10 · see citing works
Chen, T., Schmidtke, D. W., & Heller, A. (2002) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.2002.135 · Cited by 8 · see citing works
Genetic Engineering of Signaling Molecules
Feltus, A., & Daunert, S. (2002) · Elsevier eBooks · doi:10.1016/b978-044450974-1/50010-0 · Cited by 7 · see citing works
Germany - Microdialysis plus glucose sensor, theory and practical application
Owen, V. M. (1995) · Biosensors and Bioelectronics · doi:10.1016/0956-5663(95)96875-y · Cited by 5 · see citing works
Expression of vascular endothelial growth factor in primary non-small cell lung carcinoma
Zhang, L., Guoli, Y., Yuquan, X., & Xu, W. (1999) · Chinese Journal of Cancer Research · doi:10.1007/s11670-999-0037-4 · Cited by 3 · see citing works
Mathur (1997) · doi:10.1002/(sici)1097-4636(199708)36:2
Kokot (1998) · doi:10.1002/(sici)1521-4109(199811)10:16
Flagged first, then by citations
4 of the 174 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Electrochemical Glucose Biosensors
Wang, J. (2008) · Chemical Reviews · doi:10.1021/cr068123a · Cited by 3,498 · see citing works
Wearable biosensors for healthcare monitoring
Kim, J., Campbell, A. S., de Ávila, B. E.-F., & Wang, J. (2019) · Nature Biotechnology · doi:10.1038/s41587-019-0045-y · Cited by 3,373 · see citing works
Electrochemical Glucose Sensors and Their Applications in Diabetes Management
Heller, A., & Feldman, B. (2008) · Chemical Reviews · doi:10.1021/cr068069y · Cited by 1,707 · see citing works
Immobilization strategies to develop enzymatic biosensors
Sassolas, A., Blum, L. J., & Leca‐Bouvier, B. D. (2011) · Biotechnology Advances · doi:10.1016/j.biotechadv.2011.09.003 · Cited by 1,139 · see citing works
Electrochemical Non-enzymatic Glucose Sensors: A Perspective and an Evaluation
Toghill, K. E., & Compton, R. G. (2010) · International Journal of Electrochemical Science · doi:10.1016/s1452-3981(23)15359-4 · Cited by 929 · see citing works
A Comprehensive Review of Glucose Biosensors Based on Nanostructured Metal-Oxides
Rahman, M. M., Ahammad, A. J. S., Jin, J.-H., Ahn, S. J., & Lee, J.-J. (2010) · Sensors · doi:10.3390/s100504855 · Cited by 762 · see citing works
Microbial biosensors: A review
Su, L., Jia, W., Hou, C., & Yu, L. (2010) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2010.09.005 · Cited by 747 · see citing works
Biosensors based on carbon nanotubes
Balasubramanian, K., & Burghard, M. (2006) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-006-0314-8 · Cited by 726 · see citing works
Andreu-Pérez, J., Poon, C. C. Y., Merrifield, R. D., Wong, S. T. C., & Yang, G. (2015) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2015.2450362 · Cited by 707 · see citing works
Monitoring Rapid Chemical Communication in the Brain
Robinson, D. L., Hermans, A., Seipel, A. T., & Wightman, R. M. (2008) · Chemical Reviews · doi:10.1021/cr068081q · Cited by 665 · see citing works
Electroconductive hydrogels: Synthesis, characterization and biomedical applications
Guiseppi-Elie, A. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2009.12.052 · Cited by 646 · see citing works
Shankaran, D. R., Gobi, K. V., & Miura, N. (2006) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2006.09.014 · Cited by 603 · see citing works
A Review of Organic and Inorganic Biomaterials for Neural Interfaces
Fattahi, P., Yang, G., Kim, G., & Abidian, M. R. (2014) · Advanced Materials · doi:10.1002/adma.201304496 · Cited by 580 · see citing works
Biomaterials/Tissue Interactions: Possible Solutions to Overcome Foreign Body Response
Morais, J. M., Papadimitrakopoulos, F., & Burgess, D. J. (2010) · The AAPS Journal · doi:10.1208/s12248-010-9175-3 · Cited by 560 · see citing works
A Critical Review of Glucose Biosensors Based on Carbon Nanomaterials: Carbon Nanotubes and Graphene
Zhu, Z., Garcia‐Gancedo, L., Flewitt, A. J., Xie, H., Moussy, F. G., & Milne, W. I. (2012) · Sensors · doi:10.3390/s120505996 · Cited by 548 · see citing works
A contact lens with embedded sensor for monitoring tear glucose level
Yao, H., Shum, A. J., Cowan, M., Lähdesmäki, I., & Parviz, B. A. (2011) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2010.12.042 · Cited by 513 · see citing works
A Review on the Electrochemical Sensors and Biosensors Composed of Nanowires as Sensing Material
Umasankar, Y., & Chen, S. (2008) · Sensors · doi:10.3390/s8010290 · Cited by 492 · see citing works
Nonenzymatic electrochemical glucose sensor based on MnO2/MWNTs nanocomposite
Chen, J., Zhang, W., & Ye, J. (2008) · Electrochemistry Communications · doi:10.1016/j.elecom.2008.06.022 · Cited by 408 · see citing works
Liu, Y., Teng, H., Hou, H., & You, T. (2009) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2009.04.032 · Cited by 391 · see citing works
Emerging synergy between nanotechnology and implantable biosensors: A review
Vaddiraju, S., Tomazos, I., Burgess, D. J., Jain, F., & Papadimitrakopoulos, F. (2009) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2009.12.001 · Cited by 370 · see citing works
Duan, X., Li, Y., Rajan, N. K., Routenberg, D. A., Modis, Y., & Reed, M. A. (2012) · Nature Nanotechnology · doi:10.1038/nnano.2012.82 · Cited by 364 · see citing works
Biocompatible Materials for Continuous Glucose Monitoring Devices
Nichols, S. P., Koh, A., Storm, W. L., Shin, J. H., & Schoenfisch, M. H. (2013) · Chemical Reviews · doi:10.1021/cr300387j · Cited by 347 · see citing works
Status of biomolecular recognition using electrochemical techniques
Sadik, O. A., Aluoch, A. O., & Zhou, A. (2008) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2008.10.003 · Cited by 316 · see citing works
Polyelectrolyte multilayered assemblies in biomedical technologies
Costa, R. R., & Mano, J. F. (2014) · Chemical Society Reviews · doi:10.1039/c3cs60393h · Cited by 295 · see citing works
Technologies for Continuous Glucose Monitoring: Current Problems and Future Promises
Vaddiraju, S., Burgess, D. J., Tomazos, I., Jain, F. C., & Papadimitrakopoulos, F. (2010) · Journal of Diabetes Science and Technology · doi:10.1177/193229681000400632 · Cited by 285 · see citing works
Recent advances in carbon nanotube based electrochemical biosensors
Gupta, S., Murthy, C. N., & Prabha, C. R. (2017) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2017.12.038 · Cited by 279 · see citing works
A flexible and wearable glucose sensor based on functional polymers with Soft-MEMS techniques
Kudo, H., Sawada, T., Kazawa, E., Yoshida, H., Iwasaki, Y., & Mitsubayashi, K. (2006) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2006.05.006 · Cited by 255 · see citing works
Lyu, Y., & Pu, K. (2017) · Advanced Science · doi:10.1002/advs.201600481 · Cited by 246 · see citing works
Luo, L., Zhu, L., & Wang, Z. (2012) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2012.03.006 · Cited by 226 · see citing works
Biosensors and bioelectrochemistry
Murphy, L. J. (2006) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2006.02.023 · Cited by 225 · see citing works
Enzyme based amperometric biosensors
Bollella, P., & Gorton, L. G. O. (2018) · Current Opinion in Electrochemistry · doi:10.1016/j.coelec.2018.06.003 · Cited by 224 · see citing works
Pramanik, P. K. D., Solanki, A., Debnath, A., Nayyar, A., El–Sappagh, S., & Kwak, K. S. (2020) · IEEE Access · doi:10.1109/access.2020.2984269 · Cited by 221 · see citing works
A contact lens with an integrated lactate sensor
Thomas, N., Lähdesmäki, I., & Parviz, B. A. (2012) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2011.12.049 · Cited by 220 · see citing works
Pappa, A., Curto, V. F., Braendlein, M., Strakosas, X., Donahue, M. J., Fiocchi, M., Malliaras, G. G., & Owens, R. M. (2016) · Advanced Healthcare Materials · doi:10.1002/adhm.201600494 · Cited by 218 · see citing works
Amperometric glucose biosensor based on single-walled carbon nanohorns
Liu, X., Shi, L., Niu, W., Li, H., & Xu, G. (2008) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2008.02.016 · Cited by 206 · see citing works
A highly sensitive nonenzymatic glucose sensor based on NiO-modified multi-walled carbon nanotubes
Zhang, W., Chen, J., Jiang, L., Yu, Y., & Zhang, J. (2010) · Microchimica Acta · doi:10.1007/s00604-010-0288-2 · Cited by 205 · see citing works
Tailoring Zinc Oxide Nanowires for High Performance Amperometric Glucose Sensor
Zang, J., Li, C. M., Cui, X., Wang, J.-X., Sun, X. W., Dong, H., & Sun, C. Q. (2007) · Electroanalysis · doi:10.1002/elan.200603808 · Cited by 204 · see citing works
Yousefi, H., Ali, M. M., Su, H., Filipe, C. D. M., & Didar, T. F. (2018) · ACS Nano · doi:10.1021/acsnano.7b08010 · Cited by 195 · see citing works
In Vivo Analysis with Electrochemical Sensors and Biosensors
Xiao, T., Wu, F., Hao, J., Zhang, M., Yu, P., & Mao, L. (2016) · Analytical Chemistry · doi:10.1021/acs.analchem.6b04308 · Cited by 192 · see citing works
Detection of Glucose Based on Bimetallic PtCu Nanochains Modified Electrodes
Cao, X., Wang, N., Jia, S., & Shao, Y. (2013) · Analytical Chemistry · doi:10.1021/ac400292n · Cited by 187 · see citing works
A review on impedimetric immunosensors for pathogen and biomarker detection
Leva-Bueno, J., Peyman, S. A., & Millner, P. A. (2020) · Medical Microbiology and Immunology · doi:10.1007/s00430-020-00668-0 · Cited by 186 · see citing works
Koschwanez, H. E., & Reichert, W. M. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.03.034 · Cited by 181 · see citing works
In-Vivo Electrochemistry: What Can We Learn about Living Systems?
Wilson, G. S., & Johnson, M. A. (2008) · Chemical Reviews · doi:10.1021/cr068082i · Cited by 178 · see citing works
Self-citationSwitch-based biosensors: a new approach towards real-time, in vivo molecular detection
Plaxco, K. W., & Soh, H. T. (2010) · Trends in biotechnology · doi:10.1016/j.tibtech.2010.10.005 · Cited by 178 · see citing works
Zhang, M., Yu, P., & Mao, L. (2012) · Accounts of Chemical Research · doi:10.1021/ar200196h · Cited by 176 · see citing works
A flexible and wearable biosensor for tear glucose measurement
Iguchi, S., Kudo, H., Saito, T., Ogawa, M., Saito, H., Otsuka, K., Funakubo, A., & Mitsubayashi, K. (2007) · Biomedical Microdevices · doi:10.1007/s10544-007-9073-3 · Cited by 173 · see citing works
Electrochemical biosensors for Salmonella: State of the art and challenges in food safety assessment
Silva, N. F. D., Magalhães, J. M. C. S., Freire, C., & Delerue-Matos, C. M. (2017) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2017.08.019 · Cited by 173 · see citing works
Protein–polymer nanoreactors for medical applications
Palivan, C. G., Onaca, O., Delcea, M., Itel, F., & Meier, W. P. (2011) · Chemical Society Reviews · doi:10.1039/c1cs15240h · Cited by 172 · see citing works
Fluorescence lifetime imaging microscopy in life sciences
Borst, J. W., & Visser, A. J. W. G. (2010) · Measurement Science and Technology · doi:10.1088/0957-0233/21/10/102002 · Cited by 168 · see citing works
CuS nanotubes for ultrasensitive nonenzymatic glucose sensors
Zhang, X., Wang, G., Gu, A., Yan, W., & Fang, B. (2008) · Chemical Communications · doi:10.1039/b814725f · Cited by 159 · see citing works
Reduced foreign body response at nitric oxide-releasing subcutaneous implants
Hetrick, E. M., Prichard, H. L., Klitzman, B., & Schoenfisch, M. H. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.06.036 · Cited by 158 · see citing works
Li, H., Arroyo‐Currás, N., Kang, D., Ricci, F., & Plaxco, K. W. (2016) · Journal of the American Chemical Society · doi:10.1021/jacs.6b08671 · Cited by 158 · see citing works
Implantable enzyme amperometric biosensors
Kotanen, C. N., Moussy, F. G., Carrara, S., & Guiseppi‐Elie, A. (2012) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2012.03.016 · Cited by 156 · see citing works
Monitoring biomolecule concentrations in tissue using a wearable droplet microfluidic-based sensor
Nightingale, A. M., Leong, C. L., Burnish, R., Hassan, S.-U., Zhang, Y., Clough, G. F., Boutelle, M. G., Voegeli, D., & Niu, X. (2019) · Nature Communications · doi:10.1038/s41467-019-10401-y · Cited by 155 · see citing works
Dhara, K., Stanley, J., Ramachandran, T., Nair, B. G., & Babu, T. G. S. (2014) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2014.01.044 · Cited by 153 · see citing works
Zwitterionic poly(carboxybetaine) hydrogels for glucose biosensors in complex media
Yang, W. M., Xue, H., Carr, L. R., Wang, J., & Jiang, S. (2010) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2010.10.031 · Cited by 147 · see citing works
Arroyo‐Currás, N., Scida, K., Ploense, K. L., Kippin, T. E., & Plaxco, K. W. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.7b02830 · Cited by 147 · see citing works
High Performance Conducting Polymer Nanofiber Biosensors for Detection of Biomolecules
Yang, G. C., Kampstra, K. L., & Abidian, M. R. (2014) · Advanced Materials · doi:10.1002/adma.201400753 · Cited by 142 · see citing works
Molecular imprinted polymer sensors: Implications for therapeutics
Hillberg, A. L., BRAIN, K., & Allender, C. J. (2005) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2005.07.016 · Cited by 140 · see citing works
Cao, F., Guo, S., Ma, H., Shan, D., Yang, S., & Gong, J. (2010) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2010.10.013 · Cited by 135 · see citing works
Anti-Biofouling Strategies for Long-Term Continuous Use of Implantable Biosensors
Xu, J., & Lee, H. (2020) · Chemosensors · doi:10.3390/chemosensors8030066 · Cited by 134 · see citing works
Biomedical Perspective of Electrochemical Nanobiosensor
Singh, P., Pandey, S. K., Singh, J., Srivastava, S., Sachan, S., & Singh, S. K. (2015) · Nano-Micro Letters · doi:10.1007/s40820-015-0077-x · Cited by 133 · see citing works
Third-Generation Biosensor for Lactose Based on Newly Discovered Cellobiose Dehydrogenase
Stoica, L., Ludwig, R., Haltrich, D., & Gorton, L. G. O. (2005) · Analytical Chemistry · doi:10.1021/ac050327o · Cited by 129 · see citing works
A potentiometric protein sensor built with surface molecular imprinting method
Wang, Y., Zhou, Y., Sokolov, J., Rigas, B., Levón, K., & Rafailovich, M. H. (2008) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2008.04.010 · Cited by 129 · see citing works
Biosensors, Artificial Intelligence Biosensors, False Results and Novel Future Perspectives
Goumas, G. S., Vlachothanasi, E. N., Fradelos, Ε. C., & Mouliou, D. S. (2025) · Diagnostics · doi:10.3390/diagnostics15081037 · Cited by 129 · see citing works
Norton, L. W., Koschwanez, H. E., Wisniewski, N. A., Klitzman, B., & Reichert, W. M. (2007) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.31088 · Cited by 128 · see citing works
Organic Electronics for Point-of-Care Metabolite Monitoring
Pappa, A., Parlak, O., Scheiblin, G., Mailley, P., Salleo, A., & Owens, R. M. (2017) · Trends in biotechnology · doi:10.1016/j.tibtech.2017.10.022 · Cited by 128 · see citing works
Arylboronic acids: A diabetic eye on glucose sensing
Hansen, J. S., Christensen, J. B., Petersen, J. F., Høeg-Jensen, T., & Norrild, J. C. (2011) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2011.12.024 · Cited by 127 · see citing works
Aptasensors as a new sensing technology developed for the detection of MUC1 mucin: A review
Yousefi, M., Dehghani, S., Nosrati, R., Zare, H., Evazalipour, M., Mosafer, J., Tehrani, B. S., Pasdar, A., Mokhtarzadeh, A., & Ramezani, M. (2019) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2019.01.015 · Cited by 127 · see citing works
Highly selective microbiosensors for in vivo measurement of glucose, lactate and glutamate
Schuvailo, O. M., Soldatkin, O. O., Lefebvre, A., Cespuglio, R., & Soldatkin, A. P. (2006) · Analytica Chimica Acta · doi:10.1016/j.aca.2006.03.034 · Cited by 126 · see citing works
A review on visible-light induced photoelectrochemical sensors based on CdS nanoparticles
Ibrahim, I., Lim, . N., Zawawi, R. M., Tajudin, A. A., Ng, Y. H., Guo, H., & Huang, N. M. (2018) · Journal of Materials Chemistry B · doi:10.1039/c8tb00924d · Cited by 122 · see citing works
Mahshid, S. S., Mahshid, S., Dolati, A., Ghorbani, M., Yang, L., Luo, S., & Cai, Q. (2011) · Electrochimica Acta · doi:10.1016/j.electacta.2011.09.083 · Cited by 119 · see citing works
Silver Oxide Nanowalls Grown on Cu Substrate as an Enzymeless Glucose Sensor
Fang, B., Gu, A., Wang, G., Wang, W., Feng, Y., Zhang, C., & Zhang, X. (2009) · ACS Applied Materials & Interfaces · doi:10.1021/am900576z · Cited by 117 · see citing works
Microdialysis sampling of cytokines
Ao, X., & Stenken, J. A. (2006) · Methods · doi:10.1016/j.ymeth.2005.11.012 · Cited by 116 · see citing works
Miller, P. R., Gittard, S. D., Edwards, T. L., Lopez, D. M., Xiao, X., Wheeler, D. R., Monteiro-Riviere, N. A., Brozik, S. M., Polsky, R., & Narayan, R. J. (2011) · Biomicrofluidics · doi:10.1063/1.3569945 · Cited by 116 · see citing works
Electrochemical glucose biosensors
Wang, J. (2008) · Elsevier eBooks · doi:10.1016/b978-012373738-0.50005-2 · Cited by 114 · see citing works
Bio-Mimetic Sensors Based on Molecularly Imprinted Membranes
Algieri, C., Drioli, E., Guzzo, L., & Donato, L. (2014) · Sensors · doi:10.3390/s140813863 · Cited by 113 · see citing works
Nanomaterial based electrochemical sensors for in vitro detection of small molecule metabolites
Xiao, F., Wang, L., & Duan, H. (2016) · Biotechnology Advances · doi:10.1016/j.biotechadv.2016.01.006 · Cited by 113 · see citing works
Zan, X., Fang, Z., Wu, J., Xiao, F., Huo, F., & Duan, H. (2013) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2013.05.006 · Cited by 112 · see citing works
Moreira, F. T. C., Sales, M. G. F., & Lorenzo, M. D. (2016) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2016.08.104 · Cited by 112 · see citing works
Song, T., Liu, Q., Liu, J., Yang, W., Chen, R., Jing, X., Takahashi, K., & Wang, J. (2015) · Applied Surface Science · doi:10.1016/j.apsusc.2015.07.140 · Cited by 109 · see citing works
Wu, X., Hu, Y., Jin, J., Zhou, N., Wu, P., Zhang, H., & Cai, C. (2010) · Analytical Chemistry · doi:10.1021/ac100621r · Cited by 107 · see citing works
Covalent immobilization of glucose oxidase on conducting ultrananocrystalline diamond thin films
Wang, J., & Carlisle, J. A. (2005) · Diamond and Related Materials · doi:10.1016/j.diamond.2005.09.017 · Cited by 106 · see citing works
Qiu, H., & Huang, X. (2010) · Journal of Electroanalytical Chemistry · doi:10.1016/j.jelechem.2010.03.011 · Cited by 105 · see citing works
Towards wearable and implantable continuous drug monitoring: A review
Bian, S., Zhu, B., Rong, G., & Sawan, M. (2020) · Journal of Pharmaceutical Analysis · doi:10.1016/j.jpha.2020.08.001 · Cited by 105 · see citing works
Scholten, K., & Meng, E. F. (2018) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2018.02.022 · Cited by 103 · see citing works
High-Precision Control of Plasma Drug Levels Using Feedback-Controlled Dosing
Arroyo‐Currás, N., Ortega, G., Copp, D. A., Ploense, K. L., Plaxco, Z. A., Kippin, T. E., Hespanha, J. P., & Plaxco, K. W. (2018) · ACS Pharmacology & Translational Science · doi:10.1021/acsptsci.8b00033 · Cited by 102 · see citing works
Electrochemical Enzyme Biosensors Revisited: Old Solutions for New Problems
Monteiro, T., & Almeida, M. G. (2018) · Critical Reviews in Analytical Chemistry · doi:10.1080/10408347.2018.1461552 · Cited by 101 · see citing works
Photoelectrochemical sensing of glucose based on quantum dot and enzyme nanocomposites
Zheng, M., Cui, Y., Li, X., Liu, S., & Tang, Z. (2010) · Journal of Electroanalytical Chemistry · doi:10.1016/j.jelechem.2010.11.036 · Cited by 100 · see citing works
3D‐Printed Polymeric Biomaterials for Health Applications
Zhu, Y., Guo, S., Ravichandran, D., Ramanathan, A., Sobczak, M. T., Sacco, A. F., Patil, D., Thummalapalli, S. V., Pulido, T. V., Lancaster, J. N., et al. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202402571 · Cited by 100 · see citing works
Polymeric “smart” coatings to prevent foreign body response to implantable biosensors
Wang, Y., Papadimitrakopoulos, F., & Burgess, D. J. (2013) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.12.028 · Cited by 100 · see citing works
Nonenzymatic glucose sensor based on nickel ion implanted-modified indium tin oxide electrode
Tian, H., Jia, M., Zhang, M., & Hu, J. (2013) · Electrochimica Acta · doi:10.1016/j.electacta.2013.02.096 · Cited by 99 · see citing works
A highly sensitive nonenzymatic glucose sensor based on CuO nanowires
Zhang, P., Zhang, L., Zhao, G., & Fěng, F. (2011) · Microchimica Acta · doi:10.1007/s00604-011-0733-x · Cited by 96 · see citing works
Advances in assay of complement function and activation
Harboe, M., Thorgersen, E. B., & Mollnes, T. E. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.05.010 · Cited by 95 · see citing works
Vlandas, A., Kurkina, T., Ahmad, A. I., Kern, K., & Balasubramanian, K. (2010) · Analytical Chemistry · doi:10.1021/ac1007656 · Cited by 94 · see citing works
Ramírez, N. B., Salgado, A. M., & Valdman, B. (2009) · Brazilian Journal of Chemical Engineering · doi:10.1590/s0104-66322009000200001 · Cited by 91 · see citing works
Designing sensitive and selective polymer/enzyme composite biosensors for brain monitoring in vivo
O'Neill, R. D., Rocchitta, G., McMahon, C. P., Serra, P. A., & Lowry, J. P. (2007) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2007.11.008 · Cited by 91 · see citing works
Trends in Cell-Based Electrochemical Biosensors
Ding, L., Du, D., Zhang, X., & Ju, H. (2008) · Current Medicinal Chemistry · doi:10.2174/092986708786848514 · Cited by 90 · see citing works
Self-Powered Implantable Skin-Like Glucometer for Real-Time Detection of Blood Glucose Level In Vivo
Zhang, W., Zhang, L., Gao, H., Yang, W., Wang, S., Xing, L., & Xue, X. (2018) · Nano-Micro Letters · doi:10.1007/s40820-017-0185-x · Cited by 90 · see citing works
Xiang, L., Lin, Y., Yu, P., Su, L., & Mao, L. (2007) · Electrochimica Acta · doi:10.1016/j.electacta.2006.11.040 · Cited by 89 · see citing works
- Authors
- Wilson, G. S., & Gifford, R.
- Affiliations
- University of Kansas (US)
- Corresponding author
- Wilson, George S.
- ORCID
- Wilson, George S.
- Venue
- Biosensors and Bioelectronics
- Publisher
- Elsevier BV
- Published
- 2005-06
- Volume
- 20
- Issue
- 12
- Pages
- 2388-2403
- ISSN
- 0956-5663 (ISSN-L)
- OpenAlex
- W2090868198
- Cited by
- 660
- References
- 174
- Citations by year
- 2026: 17 · 2025: 21 · 2024: 14 · 2023: 16 · 2022: 17 · 2021: 13 · 2020: 23 · 2019: 27 · 2018: 36 · 2017: 25 · 2016: 37 · 2015: 39 · 2014: 40 · 2013: 50 · 2012: 52
- FWCI
- 2.85
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biosensors and Bioelectronics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrochemical sensors and biosensors
- Physical Sciences › Chemical Engineering › Bioengineering › Analytical Chemistry and Sensors
- Physical Sciences › Chemistry › Electrochemistry › Electrochemical Analysis and Applications
- Keywords
- biosensors, in vivo monitoring, glucose sensor, lactate sensor, glutamate sensor, nitric oxide sensor, ion sensors, dopamine sensor, sensor calibration, biocompatibility, continuous glucose monitoring
- MeSH terms
- Blood Glucose, Equipment Design, Transducers, Blood Glucose Self-Monitoring, Biosensing Techniques, Monitoring, Ambulatory, Cell Culture Techniques, Prostheses and Implants
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review