Cytokines and the nervous system II: actions and mechanisms of action

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

de Waal Malefyt, R., Abrams, J., Bennett, B., Figdor, C. G., & de Vries, J. E. (1991) · The Journal of experimental medicine · doi:10.1084/jem.174.5.1209 · Cited by 3,762

Pathobiology of ischaemic stroke: an integrated view

Dirnagl, U., Iadecola, C., & Moskowitz, M. A. (1999) · Trends in Neurosciences · doi:10.1016/s0166-2236(99)01401-0 · Cited by 3,943

Microglia as a source and target of cytokines

Hanisch, U. (2002) · Glia · doi:10.1002/glia.10161 · Cited by 1,645

Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action

TURNBULL, A. V., & RIVIER, C. L. (1999) · Physiological Reviews · doi:10.1152/physrev.1999.79.1.1 · Cited by 1,297

Cytokines for psychologists: Implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition.

Maier, S. F., & Watkins, L. R. (1998) · Psychological Review · doi:10.1037/0033-295x.105.1.83 · Cited by 1,130

Evidence for a cytokine model of cognitive function

McAfoose, J., & Baune, B. T. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.10.005 · Cited by 760

The cholinergic anti-inflammatory pathway: a missing link in neuroimmunomodulation

Pavlov, V. A., Wang, H., Czura, C. J., Friedman, S. G., & Tracey, K. J. (2003) · Molecular Medicine · doi:10.1007/bf03402177 · Cited by 772

Hypoxia-induced vascular endothelial growth factor expression precedes neovascularization after cerebral ischemia

Marti, H. J. H., Bernaudin, M., Bellail, A., Schoch, H., Euler, M., Petit, E., & Risau, W. (2000) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)64964-4 · Cited by 680

Research and treatment approaches to depression

Wong, M.-L., & Licinio, J. (2001) · Nature Reviews Neuroscience · doi:10.1038/35072566 · Cited by 656

“Inflammatory” Cytokines: Neuromodulators in Normal Brain?

Vitkovic, L., Bockaert, J., & Jacque, C. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.740457.x · Cited by 506

A neuromodulatory role of interleukin-1β in the hippocampus

Schneider, H., Pitossi, F., Balschun, D., Wagner, A., del Rey, A., & Besedovsky, H. O. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.13.7778 · Cited by 498

Interleukin-1β (IL-1β) and tumour necrosis factor (TNF) inhibit long-term potentiation in the rat dentate gyrus in vitro

Cunningham, A. J., Murray, C. A., O'Neill, L. A. J., Lynch, M. A., & O'Connor, J. J. (1996) · Neuroscience Letters · doi:10.1016/0304-3940(95)12252-4 · Cited by 433

The duality of the inflammatory response to traumatic brain injury

McIntosh, T. K., Lenzlinger, P. M., Morganti-Kossmann, M.-C., & Laurer, H. L. (2001) · Molecular Neurobiology · doi:10.1385/mn:24:1-3:169 · Cited by 428

ALZHEIMER'S DISEASE: Genetic Studies and Transgenic Models

Price, D. L., Tanzi, R. E., Borchelt, D. R., & Sisodia, S. S. (1998) · Annual Review of Genetics · doi:10.1146/annurev.genet.32.1.461 · Cited by 406

Leptin actions on food intake and body temperature are mediated by IL-1

Luheshi, G. N., Gardner, J. D., Rushforth, D. A., Loudon, A. S., & Rothwell, N. J. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.12.7047 · Cited by 362

Evidence That Increased Hippocampal Expression of the Cytokine Interleukin-1β Is a Common Trigger for Age- and Stress-Induced Impairments in Long-Term Potentiation

Murray, C. A., & Lynch, M. A. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-08-02974.1998 · Cited by 359

Neurogenic niche modulation by activated microglia: transforming growth factor β increases neurogenesis in the adult dentate gyrus

Battista, D., Ferrari, C. C., Gage, F. H., & Pitossi, F. J. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04539.x · Cited by 306

Inflammatory Cytokines IL-1α, IL-1β, IL-6, and TNF-α Impart Neuroprotection to an Excitotoxin Through Distinct Pathways

Carlson, N. G., Wieggel, W. A., Chen, J., Bacchi, A., Rogers, S. W., & Gahring, L. C. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.7.3963 · Cited by 301

Bi-directional immune–brain communication: implications for understanding stress, pain, and cognition

Maier, S. F. (2003) · Brain Behavior and Immunity · doi:10.1016/s0889-1591(03)00032-1 · Cited by 300

Pathophysiology of depression and mechanisms of treatment

Brigitta, B. (2002) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2002.4.1/bbondy · Cited by 286

Maternal immune activation by LPS selectively alters specific gene expression profiles of interneuron migration and oxidative stress in the fetus without triggering a fetal immune response

Oskvig, D. B., Elkahloun, A. G., Johnson, K. R., Phillips, T. M., & Herkenham, M. (2012) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2012.01.015 · Cited by 248

Specific neurodevelopmental damage in mice offspring following maternal inflammation during pregnancy

Golan, H. M., Lev, V., Hallak, M., Sorokin, Y., & Huleihel, M. (2005) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.12.023 · Cited by 253

The vagus nerve mediates behavioural depression, but not fever, in response to peripheral immune signals; a functional anatomical analysis

Konsman, J. P., Luheshi, G. N., Bluthé, R., & Dantzer, R. (2000) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2000.01319.x · Cited by 234

Cytokines and their receptors in the central nervous system: Physiology, pharmacology, and pathology

Rothwell, N. J., Luheshi, G., & Toulmond, S. (1996) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(95)02033-0 · Cited by 233

Dose-dependent effects of endotoxin on human sleep

Mullington, J., Korth, C., Hermann, D. M., Orth, A., Galanos, C., Holsboer, F., & Pollmächer, T. (2000) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.2000.278.4.r947 · Cited by 226

Cytokines, stress, and depressive illness

Anisman, H., & Merali, Z. (2002) · Brain, Behavior, and Immunity · doi:10.1016/s0889-1591(02)00009-0 · Cited by 225

Glial activation in Alzheimer's disease: the role of Aβ and its associated proteins

Meda, L. (2001) · Neurobiology of Aging · doi:10.1016/s0197-4580(01)00307-4 · Cited by 222

Novel roles for immune molecules in neural development: implications for neurodevelopmental disorders

Garay, P. (2010) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2010.00136 · Cited by 217

Pro-inflammatory cytokines and their effects in the dentate gyrus

Pickering, M., & O’Connor, J. J. (2007) · Progress in Brain Research · doi:10.1016/s0079-6123(07)63020-9 · Cited by 217

Matrix metalloproteases and their inhibitors are produced by overlapping populations of activated astrocytes

Muir, E. M., Adcock, K. H., Morgenstern, D. A., Clayton, R., von Stillfried, N., Rhodes, K., Ellis, C., Fawcett, J. W., & Rogers, J. H. (2002) · Molecular Brain Research · doi:10.1016/s0169-328x(02)00132-8 · Cited by 206

Low levels of circulating inflammatory cytokines—Do they affect human brain functions?

Pollmächer, T., Haack, M., Schuld, A., Reichenberg, A., & Yirmiya, R. (2002) · Brain, Behavior, and Immunity · doi:10.1016/s0889-1591(02)00004-1 · Cited by 202

Variations of nucleus accumbens dopamine and serotonin following systemic interleukin-1, interleukin-2 or interleukin-6 treatment

Song, C., Merali, Z., & Anisman, H. (1999) · Neuroscience · doi:10.1016/s0306-4522(98)00271-1 · Cited by 172

Interleukin-6 Is a Needed Proinflammatory Cytokine in the Prolonged Neural Activity and Transcriptional Activation of Corticotropin-Releasing Factor during Endotoxemia1

Vallières, L., & Rivest, S. (1999) · Endocrinology · doi:10.1210/endo.140.9.6983 · Cited by 157

Interleukin-1 beta modulates AMPA receptor expression and phosphorylation in hippocampal neurons

Lai, A. Y., Swayze, R. D., El-Husseini, A., & Song, C. (2006) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2006.03.001 · Cited by 151

Timecourse and corticosterone sensitivity of the brain, pituitary, and serum interleukin-1β protein response to acute stress

Nguyen, K. T., Deak, T., Will, M. J., Hansen, M. K., Hunsaker, B. N., Fleshner, M., Watkins, L. R., & Maier, S. F. (2000) · Brain Research · doi:10.1016/s0006-8993(99)02443-9 · Cited by 143

A Preliminary Study of Cytokines in Suicidal and Nonsuicidal Adolescents with Major Depression

Gabbay, V., Klein, R. G., Guttman, L. E., Babb, J. S., Alonso, C. M., Nishawala, M., Katz, Y., Gaite, M. R., & Gonzalez, C. J. (2009) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2008.0140 · Cited by 136

Acetate reduces microglia inflammatory signaling in vitro

Soliman, M. L., Puig, K. L., Combs, C. K., & Rosenberger, T. A. (2012) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2012.07955.x · Cited by 131

The p38 mitogen-activated protein kinase inhibitor SB203580 antagonizes the inhibitory effects of interleukin-1β on long-term potentiation in the rat dentate gyrus in vitro

Coogan, A. N., O'Neill, L. A. J., & O'Connor, J. J. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00100-1 · Cited by 129

An Overview of Acute Stroke Therapy: Past, Present, and Future

Fisher, M., & Schaebitz, W. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.21.3196 · Cited by 112

Induction of Neurite Outgrowth by Interleukin-6 Is Accompanied by Activation of Stat3 Signaling Pathway in a Variant PC12 Cell (E2) Line

Wu, Y. Y., & Bradshaw, R. A. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.22.13023 · Cited by 100

Parkinsonism: siblings share Helicobacter pylori seropositivity and facets of syndrome

Charlett, A., Dobbs, R. J., Dobbs, S. M., Weller, C., Brady, P., & Peterson, D. W. (2009) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1999.tb00654.x · Cited by 82

Interleukin-1β Inhibits Glutamate Release in Hippocampus of Young, But Not Aged, Rats

Murray, C. (1997) · Neurobiology of Aging · doi:10.1016/s0197-4580(97)80317-x · Cited by 84

Improvement of memory for context by inhibition of caspase‐1 in aged rats

Gemma, C., Fister, M., Hudson, C., & Bickford, P. C. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04334.x · Cited by 74

Understanding the role of SOCS signaling in neurodegenerative diseases: Current and emerging concepts

Cianciulli, A., Calvello, R., Porro, C., Trotta, T., & Panaro, M. A. (2017) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2017.07.005 · Cited by 59

Expression of CAP37, a Novel Inflammatory Mediator, in Alzheimer's Disease

Pereira, H. (1996) · Neurobiology of Aging · doi:10.1016/s0197-4580(96)00118-2 · Cited by 62

X-linked adrenoleukodystrophy

AUBOURG, P., & MANDEL, J. (1996) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1996.tb18637.x · Cited by 58

Neonatal Intrahippocampal Immune Challenge Alters Dopamine Modulation of Prefrontal Cortical Interneurons in Adult Rats

Feleder, C., Tseng, K. Y., Calhoon, G. G., & O'Donnell, P. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.09.028 · Cited by 57

Neuroimmune stress responses: reciprocal connections between the hypothalamus and the brainstem

Buller, K. M. (2003) · Stress · doi:10.1080/1025389031000092313 · Cited by 41

Neuroimmunoregulation and natural immunity

Berczi, I., Chow, D. A., & Sabbadini, E. R. (1998) · Domestic Animal Endocrinology · doi:10.1016/s0739-7240(98)00015-0 · Cited by 43

Impact of IL-1 receptor antagonist gene polymorphism on schizophrenia and bipolar disorder

Kim, S. J., Lee, H. J., Koo, H. G., Kim, J. W., Song, J. Y., Kim, M. K., Shin, D. H., Jin, S. Y., Hong, M. S., Park, H. J., et al. (2004) · Psychiatric Genetics · doi:10.1097/00041444-200409000-00009 · Cited by 40

Effects of granulocyte colony-stimulating factor on night sleep in humans

Schuld, A., Mullington, J., Hermann, D., Hinze-Selch, D., Fenzel, T., Holsboer, F., & Pollmächer, T. (1999) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1999.276.4.r1149 · Cited by 30

Inflammation- and tumor-induced anorexia and weight loss require MyD88 in hematopoietic/myeloid cells but not in brain endothelial or neural cells

Ruud, J., Wilhelms, D. B., Nilsson, A., Eskilsson, A., Tang, Y., Ströhle, P., Caesar, R., Schwaninger, M., Wunderlich, T., Bäckhed, F., et al. (2013) · The FASEB Journal · doi:10.1096/fj.12-225433 · Cited by 29

Traumatic Brain Injury and Inflammation: Emerging Role of Innate and Adaptive Immunity

Dardiotis, E., Karanikas, V., Paterakis, K., Fountas, K., & M., G. (2012) · Brain Injury - Pathogenesis, Monitoring, Recovery and Management · doi:10.5772/27840 · Cited by 22

Effekte Akuter Entzündungsreaktionen auf Gedächtnisleistungen, Befindlichkeiten und Neurale Aktivitäten: Effects of an Acute Inflammation on Memory Performance, Mood and Brain Activity

Kullmann, J. S., Grigoleit, J.-S., & Schedlowski, M. (2011) · Zeitschrift für Medizinische Psychologie · doi:10.3233/zmp-2011-2024 · Cited by 3