The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

Angel, Peter; Karin, Michael

doi:10.1016/0304-419x(91)90011-9

Cited by 450

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

Angel, Peter, Karin, Michael·1991·Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

DOI 10.1016/0304-419x(91)90011-9

Open this paper in CoChat — free account

Integrity signals

Registry

Crossref · 10.1016/0304-419x(91)90011-9

Cites

5 of 5 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

FOS encodes a critical component of the AP-1 transcription factor complex, which binds to specific cis-acting elements on gene promoters to stimulate expression of target genes.
“The FOS gene encodes a critical component of AP-1 transcription factor complex, which binds to specific cis-acting elements on gene promoters stimulating the expression of these target genes.22”
From TERT activation targets DNA methylation and multiple aging hallmarks (2024) · cites this paper as [22]

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
LAEMMLI, U. K. (1970) · Nature · doi:10.1038/227680a0 · Cited by 249,961
Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction
Yang-Yen, H.-F., Chambard, J.-C., Sun, Y.-L., Smeal, T., Schmidt, T. J., Drouin, J., & Karin, M. (1990) · Cell · doi:10.1016/0092-8674(90)90396-v · Cited by 1,553
Self-citation
The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1
Angel, P., Hattori, K., Smeal, T., & Karin, M. (1988) · Cell · doi:10.1016/0092-8674(88)90143-2 · Cited by 1,239
Self-citation
Cachectin/TNF and IL-1 Induced by Glucose-Modified Proteins: Role in Normal Tissue Remodeling
Vlassara, H., Brownlee, M., Manogue, K. R., Dinarello, C. A., & Pasagian, A. (1988) · Science · doi:10.1126/science.3259727 · Cited by 597
AP1/ jun Function Is Differentially Induced in Promotion-Sensitive and Resistant JB6 Cells
Bernstein, L. R., & Colburn, N. H. (1989) · Science · doi:10.1126/science.2541502 · Cited by 207

Flagged first, then by citations

Research works printed but not linked: 267

Lee, 1987, Nature, 325, 368, 10.1038/325368a0 · DOI
Haslinger, 1985, 82, 8572
Karin, 1987, Mol. Cell. Biol., 7, 606, 10.1128/MCB.7.2.606 · DOI
Schöler, 1986, Science, 232, 76, 10.1126/science.3006253 · DOI
Angel, 1987, Cell, 49, 729, 10.1016/0092-8674(87)90611-8 · DOI
Nishizuka, 1984, Nature, 308, 693, 10.1038/308693a0 · DOI
Angel, 1986, Mol. Cell. Biol., 6, 1760, 10.1128/MCB.6.5.1760 · DOI
Imbra, 1986, Nature, 323, 555, 10.1038/323555a0 · DOI
Imbra, 1987, Mol. Cell. Biol., 7, 1358, 10.1128/MCB.7.4.1358 · DOI
Angel, 1987, Mol. Cell. Biol., 7, 2256, 10.1128/MCB.7.6.2256 · DOI
Brenner, 1989, Nature, 337, 661, 10.1038/337661a0 · DOI
Matrisian, 1986, Mol. Cell. Biol., 6, 1679, 10.1128/MCB.6.5.1679 · DOI
Lee, 1987, Cell, 49, 741, 10.1016/0092-8674(87)90612-X · DOI
Chiu, 1987, Nature, 329, 648, 10.1038/329648a0 · DOI
Imagawa, 1987, Cell, 51, 251, 10.1016/0092-8674(87)90152-8 · DOI
Karin, 1984, Nature, 308, 513, 10.1038/308513a0 · DOI
Yamamoto, 1985, Annu. Rev. Genet., 19, 209, 10.1146/annurev.ge.19.120185.001233 · DOI
Treisman, 1985, Cell, 42, 889, 10.1016/0092-8674(85)90285-5 · DOI
Büscher, 1988, Oncogene, 3, 301
Dinter, 1987, EMBO J., 6, 4067, 10.1002/j.1460-2075.1987.tb02752.x · DOI
Lenardo, 1989, Cell, 58, 227, 10.1016/0092-8674(89)90833-7 · DOI
Bohmann, 1987, Science, 238, 1386, 10.1126/science.2825349 · DOI · Paper page
Angel, 1988, Nature, 332, 166, 10.1038/332166a0 · DOI · Paper page
Franza, 1988, Science, 239, 1150, 10.1126/science.2964084 · DOI
Rauscher, 1988, Science, 240, 1010, 10.1126/science.3130660 · DOI
Chiu, 1988, Cell, 54, 541, 10.1016/0092-8674(88)90076-1 · DOI
Sassone-Corsi, 1988, Cell, 54, 553, 10.1016/0092-8674(88)90077-3 · DOI
Bohmann, 1988, 53, 695
Maki, 1987, 84, 2848
Vogt, 1987, 84, 3316
Hope, 1985, Cell, 43, 177, 10.1016/0092-8674(85)90022-4 · DOI
Bos, 1988, Cell, 52, 705, 10.1016/0092-8674(88)90408-4 · DOI
Kryszke, 1987, Nature, 328, 254, 10.1038/328254a0 · DOI
Chiu, 1989, Cell, 59, 979, 10.1016/0092-8674(89)90754-X · DOI
Distel, 1987, Cell, 49, 835, 10.1016/0092-8674(87)90621-0 · DOI
Curran, 1982, Virology, 116, 221, 10.1016/0042-6822(82)90415-9 · DOI
Curran, 1985, Mol. Cell. Biol., 5, 167, 10.1128/MCB.5.1.167 · DOI
Sambucetti, 1986, Science, 234, 1417, 10.1126/science.3491427 · DOI
Kouzarides, 1988, Nature, 336, 646, 10.1038/336646a0 · DOI
Nakabeppu, 1988, Cell, 55, 907, 10.1016/0092-8674(88)90146-8 · DOI
Halazonetis, 1988, Cell, 55, 917, 10.1016/0092-8674(88)90147-X · DOI
Hirai, 1989, New Biol., 1, 181
Zerial, 1989, EMBO J., 8, 805, 10.1002/j.1460-2075.1989.tb03441.x · DOI
Cohen, 1989, Genes Dev., 3, 173, 10.1101/gad.3.2.173 · DOI
Matsui, 1990, Oncogene, 5, 249
Nakabeppu, 1989, EMBO J., 8, 3833, 10.1002/j.1460-2075.1989.tb08561.x · DOI
Risse, 1989, EMBO J., 8, 3825, 10.1002/j.1460-2075.1989.tb08560.x · DOI
Ryseck, 1991, Oncogene, 6, 533
Gentz, 1989, Science, 243, 1695, 10.1126/science.2494702 · DOI
Turner, 1989, Science, 243, 1689, 10.1126/science.2494701 · DOI
Ransone, 1989, Genes Dev., 3, 770, 10.1101/gad.3.6.770 · DOI
Smeal, 1989, Genes Dev., 3, 2091, 10.1101/gad.3.12b.2091 · DOI
Landschultz, 1988, Science, 240, 1759, 10.1126/science.3289117 · DOI · Paper page
O'Shea, 1989, Science, 243, 538, 10.1126/science.2911757 · DOI
O'Shea, 1989, Science, 245, 646, 10.1126/science.2503872 · DOI
Cohen, 1986, Trends Biochem. Sci., 11, 245, 10.1016/0968-0004(86)90186-6 · DOI
Gonzales, 1989, Nature, 337, 749, 10.1038/337749a0 · DOI
Benbrook, 1990, Oncogene, 5, 295
MacGregor, 1990, Oncogene, 5, 451
Montminy, 1986, 83, 6682
Kouzarides, 1989, Nature, 340, 568, 10.1038/340568a0 · DOI
Sellers, 1989, Nature, 341, 74, 10.1038/341074a0 · DOI
Neuberg, 1989, Nature, 341, 243, 10.1038/341243a0 · DOI
Rauscher, 1988, Genes Dev., 2, 1687, 10.1101/gad.2.12b.1687 · DOI
Busch, 1990, Oncogene, 5, 1549
Angel, 1989, New Biol., 1, 35
Hirai, 1990, Oncogene, 5, 39
Vogt, 1990, Adv. Canc. Res., 55, 1, 10.1016/S0065-230X(08)60466-2 · DOI
Hai, 1989, Genes Dev., 3, 2083, 10.1101/gad.3.12b.2083 · DOI
Neuberg, 1989, Nature, 338, 589, 10.1038/338589a0 · DOI
Cohen, 1990, Oncogene, 5, 929
Ransone, 1990, 87, 3806
Ptashne, 1989, Nature, 335, 683, 10.1038/335683a0 · DOI
Bohmann, 1989, Cell, 59, 709, 10.1016/0092-8674(89)90017-2 · DOI
Theill, 1989, Nature, 342, 945, 10.1038/342945a0 · DOI
Bodner, 1989, Cell, 55, 505, 10.1016/0092-8674(88)90037-2 · DOI
Abate, 1990, Mol. Cell. Biol., 10, 5532, 10.1128/MCB.10.10.5532 · DOI
Sassone-Corsi, 1988, Nature, 336, 692, 10.1038/336692a0 · DOI
Greenberg, 1984, Nature, 311, 433, 10.1038/311433a0 · DOI
Kruijer, 1984, Nature, 312, 711, 10.1038/312711a0 · DOI
Müller, 1984, Nature, 312, 716, 10.1038/312716a0 · DOI
Ryseck, 1988, Nature, 334, 535, 10.1038/334535a0 · DOI
Lamph, 1988, Nature, 334, 629, 10.1038/334629a0 · DOI
Rahmsdorf, 1987, Nucleic Acids Res., 15, 1643, 10.1093/nar/15.4.1643 · DOI
Schönthal, 1988, 53, 779
Kim, 1990, Mol. Cell. Biol., 10, 1492, 10.1128/MCB.10.4.1492 · DOI · Paper page
Pertovaara, 1989, Mol. Cell. Biol., 9, 1255, 10.1128/MCB.9.3.1255 · DOI
Edwards, 1987, EMBO J., 6, 1899, 10.1002/j.1460-2075.1987.tb02449.x · DOI · Paper page
Kraft, 1982, J. Biol. Chem., 257, 13193, 10.1016/S0021-9258(18)33427-6 · DOI
Rodriguez-Pena, 1984, Biochem. Biophys. Res. Commun., 120, 1053, 10.1016/S0006-291X(84)80213-2 · DOI
Hattori, 1988, 85, 9148
Nishimura, 1988, Oncogene, 3, 659
Sassone-Corsi, 1988, Nature, 334, 314, 10.1038/334314a0 · DOI
Schönthal, 1989, Oncogene, 4, 629
Verma, 1987, Cell, 513, 10.1016/0092-8674(87)90115-2 · DOI
Herrlich, 1989, Trends Genet., 5, 112, 10.1016/0168-9525(89)90041-3 · DOI
Curran, 1985, Science, 229, 1265, 10.1126/science.4035354 · DOI
Colletta, 1986, Science, 233, 458, 10.1126/science.3726540 · DOI
Angel, 1985, Cancer Cells, 3, 315
Shibanuma, 1987, Eur. J. Biochem., 164, 15, 10.1111/j.1432-1033.1987.tb10985.x · DOI
Fisch, 1987, Mol. Cell. Biol., 7, 3490, 10.1128/MCB.7.10.3490 · DOI
Morgan, 1986, Nature, 322, 552, 10.1038/322552a0 · DOI
Curran, 1986, 83, 8521
Bartel, 1989, Genes Dev., 3, 304, 10.1101/gad.3.3.304 · DOI
Greenberg, 1986, Science, 234, 80, 10.1126/science.3749894 · DOI
Andrews, 1987, Mol. Cell. Biol., 7, 3452, 10.1128/MCB.7.10.3452 · DOI
Bravo, 1987, Cell, 48, 251, 10.1016/0092-8674(87)90428-4 · DOI
Greenberg, 1986, Mol. Cell. Biol., 7, 1217, 10.1128/MCB.7.3.1217 · DOI
Riabowol, 1988, Nature, 336, 83, 10.1038/336083a0 · DOI
Gilman, 1986, Mol. Cell. Biol., 6, 4305, 10.1128/MCB.6.12.4305 · DOI
Prywes, 1986, Cell, 47, 777, 10.1016/0092-8674(86)90520-9 · DOI
Gilman, 1988, Genes Dev., 2, 394, 10.1101/gad.2.4.394 · DOI
Hayes, 1987, 84, 1272
Treisman, 1987, EMBO J., 6, 2711, 10.1002/j.1460-2075.1987.tb02564.x · DOI
Norman, 1988, Cell, 55, 989, 10.1016/0092-8674(88)90244-9 · DOI
Shaw, 1989, Cell, 56, 563, 10.1016/0092-8674(89)90579-5 · DOI
Schröter, 1990, EMBO J., 9, 1123, 10.1002/j.1460-2075.1990.tb08218.x · DOI
Herrera, 1989, Nature, 340, 68, 10.1038/340068a0 · DOI
Manak, 1990, Genes Dev., 4, 955, 10.1101/gad.4.6.955 · DOI
Mechta, 1989, New Biol., 1, 297
Yang-Yen, 1990, New Biol., 2, 351
Cohen, 1982, Nature, 227, 680
Boyle, 1991, Cell, 64, 573, 10.1016/0092-8674(91)90241-P · DOI
Hai, 1988, Genes Dev., 2, 1216, 10.1101/gad.2.10.1216 · DOI
Woodget, 1984, Biochim. Biophys. Acta, 788, 339, 10.1016/0167-4838(84)90047-5 · DOI
Seamon, 1986, Adv. Cycl. Nucl. Prot. Phosphoryl. Res., 20, 1
Barber, 1987, Mol. Cell. Biol., 77, 2201, 10.1128/MCB.7.6.2201 · DOI
Piette, 1988, 85, 3401
Jonat, 1990, Cell, 62, 1189, 10.1016/0092-8674(90)90395-U · DOI
Schüle, 1990, Cell, 62, 1217, 10.1016/0092-8674(90)90397-W · DOI
Lucibello, 1990, EMBO J., 9, 2827, 10.1002/j.1460-2075.1990.tb07471.x · DOI
Rochette-Egly, 1990, Genes Dev., 4, 137, 10.1101/gad.4.1.137 · DOI
Offringa, 1990, Cell, 62, 527, 10.1016/0092-8674(90)90017-9 · DOI
Frisch, 1990, Oncogene, 5, 75
Parillo, 1979, Annu. Rev. Pharmacol. Toxicol., 19, 179, 10.1146/annurev.pa.19.040179.001143 · DOI
Brinckerhoff, 1986, Biochemistry, 25, 6378, 10.1021/bi00369a006 · DOI
Mordacq, 1989, Genes Dev., 3, 760, 10.1101/gad.3.6.760 · DOI
Evans, 1988, Science, 240, 889, 10.1126/science.3283939 · DOI
Berk, 1986, Cancer Surv., 5, 367
Jones, 1988, Genes Dev., 2, 267, 10.1101/gad.2.3.267 · DOI
Offringa, 1988, Nucleic Acids Res., 16, 10973, 10.1093/nar/16.23.10973 · DOI
Gill, 1988, Nature, 334, 721, 10.1038/334721a0 · DOI
Schütte, 1989, 86, 2257
Hirai, 1989, EMBO J., 8, 1433, 10.1002/j.1460-2075.1989.tb03525.x · DOI
Schütte, 1989, Cell, 59, 987, 10.1016/0092-8674(89)90755-1 · DOI
Monuki, 1989, Neuron, 3, 783, 10.1016/0896-6273(89)90247-X · DOI
Nakabeppu, 1991, Cell, 64, 751, 10.1016/0092-8674(91)90504-R · DOI
Hoeffler, 1988, Science, 242, 1430, 10.1126/science.2974179 · DOI
Ryder, 1989, 86, 1500
Alcorn, 1990, Hepatology, 11, 909, 10.1002/hep.1840110602 · DOI
Mitchell, 1986, Cell, 45, 497, 10.1016/0092-8674(86)90281-3 · DOI
Shaw, 1986, Cell, 46, 659, 10.1016/0092-8674(86)90341-7 · DOI
Shyu, 1989, Genes Dev., 3, 60, 10.1101/gad.3.1.60 · DOI
Fort, 1987, Nucleic Acids Res., 15, 5657, 10.1093/nar/15.14.5657 · DOI
Schönthal, 1988, Cell, 54, 325, 10.1016/0092-8674(88)90195-X · DOI
Wilson, 1988, EMBO J., 7, 4193, 10.1002/j.1460-2075.1988.tb03316.x · DOI
Curran, 1984, Cell, 36, 259, 10.1016/0092-8674(84)90219-8 · DOI
Schuermann, 1989, Cell, 56, 507, 10.1016/0092-8674(89)90253-5 · DOI
Gius, 1990, Mol. Cell. Biol., 10, 4243, 10.1128/MCB.10.8.4243 · DOI
König, 1989, EMBO J., 8, 2559, 10.1002/j.1460-2075.1989.tb08394.x · DOI
Shaw, 1989, EMBO J., 8, 2567, 10.1002/j.1460-2075.1989.tb08395.x · DOI
Lucibello, 1989, Cell, 59, 999, 10.1016/0092-8674(89)90756-3 · DOI
Prywes, 1988, 85, 7206
Strickland, 1978, Cell, 15, 393, 10.1016/0092-8674(78)90008-9 · DOI
Strickland, 1981, Cell, 24, 277, 10.1016/0092-8674(81)90313-5 · DOI
Grover, 1983, 10, 69
De Groot, 1990, Nucleic Acids Res., 18, 3195, 10.1093/nar/18.11.3195 · DOI
Rickles, 1989, Mol. Cell. Biol., 9, 1691, 10.1128/MCB.9.4.1691 · DOI
Oshima, 1990, Genes Dev., 4, 835, 10.1101/gad.4.5.835 · DOI
De Groot, 1990, EMBO J., 9, 1831, 10.1002/j.1460-2075.1990.tb08308.x · DOI
De Thé, 1990, Nature, 343, 177, 10.1038/343177a0 · DOI
Schüle, 1990, Cell, 61, 497, 10.1016/0092-8674(90)90531-I · DOI
Lafyatis, 1990, Mol. Endocrinol., 4, 973, 10.1210/mend-4-7-973 · DOI
Demay, 1990, 87, 369
Torti, 1985, Science, 229, 867, 10.1126/science.3839597 · DOI
Topper, 1980, Physiol. Rev., 60, 1049, 10.1152/physrev.1980.60.4.1049 · DOI
Doppler, 1989, 86, 104
Ryder, 1988, 85, 8464
Quantin, 1988, Nature, 334, 538, 10.1038/334538a0 · DOI
Riabowol, 1988, Mol. Cell. Biol., 8, 1670, 10.1128/MCB.8.4.1670 · DOI
Holt, 1986, 83, 4794
Wasylyk, 1988, EMBO J., 7, 2475, 10.1002/j.1460-2075.1988.tb03094.x · DOI
Wasylyk, 1989, Mol. Cell. Biol., 9, 2247, 10.1128/MCB.9.5.2247 · DOI
Muegge, 1989, Science, 246, 249, 10.1126/science.2799385 · DOI
Boonstra, 1983, J. Cell Biol., 97, 92, 10.1083/jcb.97.1.92 · DOI
Williams, 1990, J. Biol. Chem., 265, 18166, 10.1016/S0021-9258(17)44733-8 · DOI
Roberts, 1985, 82, 119
Müller, 1984, Nature, 311, 438, 10.1038/311438a0 · DOI
Weinberg, 1985, Science, 230, 770, 10.1126/science.2997917 · DOI
Rozengurt, 1986, Science, 234, 161, 10.1126/science.3018928 · DOI
Berridge, 1986, Cancer Surv., 5, 413
Bishop, 1987, Science, 235, 305, 10.1126/science.3541204 · DOI
Bos, 1990, Genes Dev., 4, 1677, 10.1101/gad.4.10.1677 · DOI
Struhl, 1988, Nature, 332, 649, 10.1038/332649a0 · DOI
Alani, R., Brown, P., Binetruy, B., Dosaka, H., Rosenberg, R., Smeal, T., Angel, P., Karin, M. and Birrer, M. (1990), in press.
Baichwal, 1990, Cell, 63, 815, 10.1016/0092-8674(90)90147-7 · DOI
Imler, 1988, Nucleic Acids Res., 16, 3005, 10.1093/nar/16.7.3005 · DOI
Finkel, 1966, Science, 151, 698, 10.1126/science.151.3711.698 · DOI
Miller, 1984, Cell, 36, 51, 10.1016/0092-8674(84)90073-4 · DOI
Jenuwein, 1985, Cell, 41, 629, 10.1016/S0092-8674(85)80035-0 · DOI

200 of 267 shown

Sorted by citations

Free Radicals in the Physiological Control of Cell Function
Dröge, W. (2002) · Physiological Reviews · doi:10.1152/physrev.00018.2001 · Cited by 9,855
Allergic Rhinitis and Its Impact on Asthma
Bousquet, J., van Cauwenberge, P., & Khaltaev, N. (2001) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2001.118891 · Cited by 3,588
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
Dérijard, B., Hibi, M., Wu, I.-H., Barrett, T., Su, B., Deng, T., Karin, M., & Davis, R. J. (1994) · Cell · doi:10.1016/0092-8674(94)90380-8 · Cited by 3,188
Self-citation
AP-1 as a regulator of cell life and death
Shaulian, E., & Karin, M. (2002) · Nature Cell Biology · doi:10.1038/ncb0502-e131 · Cited by 2,961
Self-citation
A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors
Kamei, Y., Xu, L., Heinzel, T., Torchia, J., Kurokawa, R., Gloss, B., Lin, S.-C., Heyman, R. A., Rose, D. W., Glass, C. K., et al. (1996) · Cell · doi:10.1016/s0092-8674(00)81118-6 · Cited by 2,150
Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death
Liu, Z.-G., Hsu, H., Goeddel, D. V., & Karin, M. (1996) · Cell · doi:10.1016/s0092-8674(00)81375-6 · Cited by 1,937
Self-citation
Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.
Hibi, M., Lin, A., Smeal, T., Minden, A., & Karin, M. (1993) · Genes & Development · doi:10.1101/gad.7.11.2135 · Cited by 1,886
Self-citation
Redox regulation of cell survival
Trachootham, D., Lu, W., Ogasawara, M. A., Valle, N. R.-D., & Huang, P. (2008) · Antioxidants & Redox Signaling · doi:10.1089/ars.2007.1957 · Cited by 1,781
Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways
Whitmarsh, A. J., & Davis, R. J. (1996) · Journal of Molecular Medicine · doi:10.1007/s001090050063 · Cited by 1,543
Mechanisms in the Pathogenesis of Asbestosis and Silicosis
MOSSMAN, B. T., & CHURG, A. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.157.5.9707141 · Cited by 971
Cellular senescence and tumor suppressor gene p16
Rayess, H., Wang, M. B., & Srivatsan, E. S. (2012) · International Journal of Cancer · doi:10.1002/ijc.27316 · Cited by 825
Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β-induced transcription
Zhang, Y., Feng, X.-H., & Derynck, R. (1998) · Nature · doi:10.1038/29814 · Cited by 809
Cellular signaling and factors involved in Müller cell gliosis: neuroprotective and detrimental effects
Bringmann, A., Iandiev, I., Pannicke, T., Wurm, A., Hollborn, M., Wiedemann, P., Osborne, N. N., & Reichenbach, A. (2009) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2009.07.001 · Cited by 761
Mitogen-activated protein kinase cascades and regulation of gene expression
Su, B., & Karin, M. (1996) · Current Opinion in Immunology · doi:10.1016/s0952-7915(96)80131-2 · Cited by 747
Self-citation
Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant.
Sun, S., Sprenger, C. C. T., Vessella, R. L., Haugk, K., Soriano, K., Mostaghel, E. A., Page, S. T., Coleman, I. M., Nguyen, H. M., Sun, H., et al. (2010) · Journal of Clinical Investigation · doi:10.1172/jci41824 · Cited by 748
Mechanism and Function of a Newly Identified CpG DNA Motif in Human Primary B Cells
Hartmann, G., & Krieg, A. M. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.2.944 · Cited by 605
Estrogens suppress RANK ligand-induced osteoclast differentiation via a stromal cell independent mechanism involving c-jun repression.
Shevde, N. K., Bendixen, A. C., Dienger, K. M., & Pike, J. W. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.130200197 · Cited by 502
Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells.
Dong, Z., Birrer, M. J., Watts, R. G., Matrisian, L. M., & Colburn, N. H. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.2.609 · Cited by 386
Heterodimer formation of cJun and ATF‐2 is responsible for induction of c‐jun by the 243 amino acid adenovirus E1A protein.
van Dam, H., Duyndam, M., Rottier, R., Bosch, A., de Vries‐Smits, L., Herrlich, P., Zantema, A., Angel, P., & van der Eb, A. J. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb05680.x · Cited by 375
Self-citation
UVA-mediated activation of signaling pathways involved in skin tumor promotion and progression
Bachelor, M. A., & Bowden, G. T. (2004) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2003.09.017 · Cited by 268
Negative regulation of nuclear factor-kappaB activation and function by glucocorticoids
Almawi, W., & Melemedjian, O. (2002) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0280069 · Cited by 242
Persistent induction of c-fos and c-jun expression by asbestos.
Heintz, N. H., Janssen, Y. M., & Mossman, B. T. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.8.3299 · Cited by 205
The DNA binding-independent function of the glucocorticoid receptor mediates repression of AP-1-dependent genes in skin
Tuckermann, J. P., Reichardt, H. M., Arribas, R., Richter, K. H., Schütz, G., & Angel, P. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.147.7.1365 · Cited by 196
A direct physical association between ETS and AP-1 transcription factors in normal human T cells
Bassuk, A. G., & Leiden, J. M. (1995) · Immunity · doi:10.1016/1074-7613(95)90092-6 · Cited by 186
A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-κB or ODC transactivation
Yang, H.-S., Jansen, A. P., Nair, R., Shibahara, K., Verma, A. K., Cmarik, J. L., & Colburn, N. H. (2001) · Oncogene · doi:10.1038/sj.onc.1204137 · Cited by 185
Nicotinic regulation of c-fos and osteopontin expression in human-derived osteoblast-like cells and human trabecular bone organ culture
Walker, L. M., Preston, M. R., Magnay, J. L., Thomas, P. B. M., & El Haj, A. J. (2001) · Bone · doi:10.1016/s8756-3282(01)00427-6 · Cited by 168
Effect of oxidative DNA damage in promoter elements on transcription factor binding
Ghosh, R., & Mitchell, D. L. (1999) · Nucleic Acids Research · doi:10.1093/nar/27.15.3213 · Cited by 152
CD28: a signalling perspective
WARD, S. G. (1996) · Biochemical Journal · doi:10.1042/bj3180361 · Cited by 149
Leishmania-Induced Inactivation of the Macrophage Transcription Factor AP-1 Is Mediated by the Parasite Metalloprotease GP63
Contreras, I., Gómez, M. A., Nguyen, O., Shio, M. T., McMaster, R. W., & Olivier, M. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1001148 · Cited by 143
Untitled work
Kang (2001) · doi:10.1016/s0749-0690(05)70091-4 · Cited by 125
Coenzyme Q10 Improves Lipid Metabolism and Ameliorates Obesity by Regulating CaMKII-Mediated PDE4 Inhibition
Xu, Z., Huo, J., Ding, X., Yang, M., Li, L., Dai, J., Hosoe, K., Kubo, H., Mori, M., Higuchi, K., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-08899-7 · Cited by 108
The response of c-Jun/AP-1 to chronic hypoxia is hypoxia-inducible factor 1α dependent
Laderoute, K. R., Calaoagan, J. M., Gustafson-Brown, C., Knapp, A. M., Li, G.-C., Mendonca, H. L., Ryan, H. E., Wang, Z., & Johnson, R. S. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.8.2515-2523.2002 · Cited by 105
TERT activation targets DNA methylation and multiple aging hallmarks
Shim, H. S., Iaconelli, J., Shang, X., Li, J., Lan, Z. D., Jiang, S., Nutsch, K., Beyer, B. A., Lairson, L. L., Boutin, A. T., et al. (2024) · Cell · doi:10.1016/j.cell.2024.05.048 · Cited by 104
Methamphetamine potentiates HIV-1 Tat protein-mediated activation of redox-sensitive pathways in discrete regions of the brain
Flora, G., Lee, Y. W., Nath, A., Hennig, B., Maragos, W., & Toborek, M. (2003) · Experimental Neurology · doi:10.1006/exnr.2002.8048 · Cited by 99
Transcriptional activation of Jun and Fos members of the AP‐1 complex is a conserved signature of immune aging that contributes to inflammaging
Karakaslar, E. O., Katiyar, N., Hasham, M., Youn, A., Sharma, S., Chung, C., Marches, R., Korstanje, R., Banchereau, J., & Ucar, D. (2023) · Aging Cell · doi:10.1111/acel.13792 · Cited by 98
JunD stabilization results in inhibition of normal intestinal epithelial cell growth through P21 after polyamine depletion
Li, L., Liu, L., Rao, J. N., Esmaili, A., Strauch, E. D., Bass, B. L., & Wang, J. (2002) · Gastroenterology · doi:10.1053/gast.2002.35386 · Cited by 91
Methamphetamine-Induced TNF-α Gene Expression and Activation of AP-1 in Discrete Regions of Mouse Brain
Toborek, M., Flora, G., Lee, Y. W., Nath, A., Maragos, W., & Hennig, B. (2002) · NeuroMolecular Medicine · doi:10.1385/nmm:2:1:71 · Cited by 89
Delayed Wound Healing and Epidermal Hyperproliferation in Mice Lacking JunB in the Skin
Florin, L., Knebel, J., Zigrino, P., Vonderstrass, B., Mauch, C., Schorpp-Kistner, M., Szabowski, A., & Angel, P. (2006) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700123 · Cited by 79
Self-citation
Inhibitory effects of fucoidan on activation of epidermal growth factor receptor and cell transformation in JB6 Cl41 cells
Lee, N. Y., Ermakova, S. P., Zvyagintseva, T. N., Kang, K. W., Dong, Z., & Choi, H. S. (2008) · Food and Chemical Toxicology · doi:10.1016/j.fct.2008.01.025 · Cited by 75
Equol, a Metabolite of the Soybean Isoflavone Daidzein, Inhibits Neoplastic Cell Transformation by Targeting the MEK/ERK/p90RSK/Activator Protein-1 Pathway
Kang, N. J., Lee, K. W., Rogozin, E. A., Cho, Y.-Y., Heo, Y.-S., Bode, A. M., Lee, H. J., & Dong, Z. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m701459200 · Cited by 71
Differences in expression of transcription factor AP-1 in human promyelocytic HL-60 cells during differentiation towards macrophages versus granulocytes
Mollinedo, F., Gajate, C., Tugores, A., Flores, I., & Naranjo, J. R. (1993) · Biochemical Journal · doi:10.1042/bj2940137 · Cited by 63
Expression of Jun family members in human colorectal adenocarcinoma
Wang, H., Birkenbach, M., & Hart, J. (2000) · Carcinogenesis · doi:10.1093/carcin/21.7.1313 · Cited by 64
Mice lacking c-fos have normal hematopoietic stem cells but exhibit altered B-cell differentiation due to an impaired bone marrow environment
Okada, S., Wang, Z.-Q., Grigoriadis, A. E., Wagner, E. F., & von Rüden, T. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.1.382-390.1994 · Cited by 62
Possible involvement of group I mGluRs in neuroprotective effect of theanine
Nagasawa, K., Aoki, H., Yasuda, E., Nagai, K., Shimohama, S., & Fujimoto, S. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.05.143 · Cited by 48
Oxidative Stress and Heat Shock Stimulate RGS2 Expression in 1321N1 Astrocytoma Cells
Zmijewski, J. W., Song, L., Harkins, L., Cobbs, C. S., & Jope, R. S. (2001) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.2001.2430 · Cited by 48
Gene expression in learning processes
Kaczmarek, L. (2000) · Acta Neurobiologiae Experimentalis · doi:10.55782/ane-2000-1361 · Cited by 44
Patterns of c-fosand c-junProto-oncogene Expression, Apoptosis, and Proliferation in Rat Pleural Mesothelial Cells Exposed to Erionite or Asbestos Fibers
Timblin, C. R., Guthrie, G. D., Janssen, Y. W. M., Walsh, E. S., Vacek, P., & Mossman, B. T. (1998) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1998.8450 · Cited by 42
Fucoidan from Laminaria cichorioides inhibits AP‐1 transactivation and cell transformation in the mouse epidermal JB6 cells
Lee, N. Y., Ermakova, S. P., Choi, H., Kusaykin, M. I., Shevchenko, N. M., Zvyagintseva, T. N., & Choi, H. S. (2008) · Molecular Carcinogenesis · doi:10.1002/mc.20428 · Cited by 40
Anti-VEGF Drugs in the Treatment of Multiple Myeloma Patients
Ria, R., Melaccio, A., Racanelli, V., & Vacca, A. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9061765 · Cited by 40
In vivo and in vitro induction of c-fos in avian exocrine salt gland cells
Hildebrandt, J.-P., Gerstberger, R., & Schwarz, M. (1998) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1998.275.4.c951 · Cited by 36
Upregulation of Intermediate-Conductance Ca2+-Activated K+ Channels (KCNN4) in Porcine Coronary Smooth Muscle Requires NADPH Oxidase 5 (NOX5)
Gole, H. K. A., Tharp, D. L., & Bowles, D. K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0105337 · Cited by 36
Activation of the Ferritin H Enhancer, FER-1, by the Cooperative Action of Members of the AP1 and Sp1 Transcription Factor Families
Tsuji, Y., Torti, S. V., & Torti, F. M. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.5.2984 · Cited by 36
17α-Hydroxylase (CYP17) Expression and Subsequent Androstenedione Production in the Human Ovary
Patel, S. S., Beshay, V. E., Escobar, J. C., & Carr, B. R. (2010) · Reproductive Sciences · doi:10.1177/1933719110379055 · Cited by 32
α-Ionone Protects Against UVB-Induced Photoaging in Human Dermal Fibroblasts
Tong, T., Park, J., Moon, Y., Kang, W., & Park, T. (2019) · Molecules · doi:10.3390/molecules24091804 · Cited by 28
SRC kinase drives multidrug resistance induced by KRAS-G12C inhibition
Song, X., Zhou, Z., Elmezayen, A., Wu, R., Yu, C., Gao, B., Minna, J. D., Westover, K. D., Zeh, H. J., Kroemer, G., et al. (2024) · Science Advances · doi:10.1126/sciadv.adq4274 · Cited by 26
Age-dependent alterations of c-fos and growth regulation in human fibroblasts expressing the HPV16 E6 protein.
Yan, Y., Ouellette, M. M., Shay, J. W., & Wright, W. E. (1996) · Molecular Biology of the Cell · doi:10.1091/mbc.7.6.975 · Cited by 9
SENIEUR status of the originating cell donor negates certain ‘anti-immunosenescence’ effects of ebselen and N-acetyl cysteine in human T cell clone cultures
Marthandan, S., Freeburn, R., Steinbrecht, S., Pawelec, G., & Barnett, Y. (2014) · Immunity & Ageing · doi:10.1186/s12979-014-0017-5 · Cited by 5

Authors: Angel, P., & Karin, M.
Venue: Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Publisher: Elsevier BV
Published: 1991-12
Volume: 1072
Issue: 2-3
Pages: 129-157
ISSN: 0304-419X
DOI: 10.1016/0304-419x(91)90011-9
Cited by: 450
References: 5
Language: en
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Metadata

Record

About these checks