Cited by 150Smoking Behavior and CessationSubstance Abuse Treatment and OutcomesPrenatal Substance Exposure Effects

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Abstinence effects as predictors of 28-day relapse in smokers

Swan, Gary E., Ward, Marcia M., Jack, Lisa M.·1996·Addictive Behaviors

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Abstract

The present analysis sought to determine the relationship between abstinence effects in 64 ex-smokers (mean age = 41.1 years) and the rate at which they relapsed over 4 weeks of biochemically confirmed follow-up. This analysis focused on six abstinence effects that play a central role in the DSM-III-R and DSM IV definitions of withdrawal from nicotine: anger, depression, craving, appetite, confusion, and tension. Significant increases were observed for all six symptoms following cessation, and, with the exception of craving, substantial intercorrelations among the abstinence effects were noted. Cox proportional hazards survival models identified increases in anger, depressed mood, and craving to be significantly associated with a shorter time to relapse (all p < .03). Stepwise Cox proportional hazards survival analysis identified increases in depressed mood and craving as the most significant combination of abstinence effects in relation to time to relapse. A more stringent test of the potency of the relationship between these abstinence effects and time to relapse was conducted in which two other risk factors in this sample, method of quitting and education level, were also included in the model testing sequence. Even after adjustment for these significant risk factors, the increase in craving remained a significant predictor of a higher rate of relapse. This result suggests a robustness to this particular abstinence effect as a determinant of the speed with which ex-smokers relapse over a 1-month interval after cessation.

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Authors: Swan, G. E., Ward, M. M., & Jack, L. M.
Affiliations: SRI International (US)
Corresponding author: Swan, Gary E.
ORCID: Swan, Gary E.
Ward, Marcia M.
Jack, Lisa M.
Venue: Addictive Behaviors
Publisher: Elsevier BV
Published: 1996-07
Volume: 21
Issue: 4
Pages: 481-490
ISSN: 0306-4603 (ISSN-L)
DOI: 10.1016/0306-4603(95)00070-4
OpenAlex: W2055703665
Cited by: 150
References: 33
Citations by year: 2026: 1 · 2023: 3 · 2022: 2 · 2020: 2 · 2019: 2 · 2018: 2 · 2017: 3 · 2016: 4 · 2015: 7 · 2014: 10 · 2013: 5 · 2012: 5
FWCI: 2.70
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Addictive Behaviors (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
Keywords: nicotine withdrawal, smoking relapse, former smokers, craving, depression, anger, time to relapse, recurrence risk factors, educational attainment
MeSH terms: Adult, Female, Follow-Up Studies, Humans, Male, Neurologic Examination, Nicotine, Psychiatric Status Rating Scales, Risk Factors, Substance Withdrawal Syndrome, Smoking Cessation

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Abstinence effects as predictors of 28-day relapse in smokers

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