Beyond GWASs: Illuminating the Dark Road from Association to Function

MicroRNAs: Target Recognition and Regulatory Functions

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Multiplex Genome Engineering Using CRISPR/Cas Systems

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Finding the missing heritability of complex diseases

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

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An integrated map of genetic variation from 1,092 human genomes

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High-Resolution Profiling of Histone Methylations in the Human Genome

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The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

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Systematic Localization of Common Disease-Associated Variation in Regulatory DNA

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Capturing Chromosome Conformation

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Biological, clinical and population relevance of 95 loci for blood lipids

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DNA methylation and human disease

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Genome-wide association studies for common diseases and complex traits

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A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila

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Genome editing with engineered zinc finger nucleases

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A TALE nuclease architecture for efficient genome editing

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Transcriptome and genome sequencing uncovers functional variation in humans

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Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease

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Linkage disequilibrium in the human genome

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An oestrogen-receptor-α-bound human chromatin interactome

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Systematic identification of trans eQTLs as putative drivers of known disease associations

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The long-range interaction landscape of gene promoters

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Prospects for whole-genome linkage disequilibrium mapping of common disease genes

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Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS

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Epigenome-wide association studies for common human diseases

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Extensive Promoter-Centered Chromatin Interactions Provide a Topological Basis for Transcription Regulation

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Genetic analysis of genome-wide variation in human gene expression

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Chromosome Conformation Capture Carbon Copy (5C): A massively parallel solution for mapping interactions between genomic elementsPreprint

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From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

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Large-scale genotyping identifies 41 new loci associated with breast cancer risk

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Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

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Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain

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Analysing biological pathways in genome-wide association studies

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Common Regulatory Variation Impacts Gene Expression in a Cell Type–Dependent Manner

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Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations

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Genome-wide association study identifies five new breast cancer susceptibility loci

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Epigenetics as a unifying principle in the aetiology of complex traits and diseases

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The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer

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An Erythroid Enhancer of <i>BCL11A</i> Subject to Genetic Variation Determines Fetal Hemoglobin Level

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CTCF-mediated functional chromatin interactome in pluripotent cells

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9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

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A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33

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Genetics and Beyond – The Transcriptome of Human Monocytes and Disease Susceptibility

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Needles in stacks of needles: finding disease-causal variants in a wealth of genomic data

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Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

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The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling

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Targeted RNA sequencing reveals the deep complexity of the human transcriptome

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A survey of genetic human cortical gene expression

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Patterns of Cis Regulatory Variation in Diverse Human Populations

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The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits

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Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice

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Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells

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Genomic surveys by methylation-sensitive SNP analysis identify sequence-dependent allele-specific DNA methylation

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New gene functions in megakaryopoiesis and platelet formation

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Regulation of RNA Polymerase II Transcription by Sequence-Specific DNA Binding Factors

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The Architecture of Gene Regulatory Variation across Multiple Human Tissues: The MuTHER Study

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Use of genome-wide association studies for drug repositioning

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Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression

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Downregulation of Death-Associated Protein Kinase 1 (DAPK1) in Chronic Lymphocytic Leukemia

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Variation and genetic control of protein abundance in humans

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Knockout mice created by TALEN-mediated gene targeting

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8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC

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Breast cancer risk–associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression

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Drug-sensitive FGFR2 mutations in endometrial carcinoma

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GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

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DNA methylation of distal regulatory sites characterizes dysregulation of cancer genes

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Multiple Loci With Different Cancer Specificities Within the 8q24 Gene Desert

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Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA

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Differential microRNA regulation of HLA-C expression and its association with HIV control

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Environmental epigenetics: prospects for studying epigenetic mediation of exposure–response relationships

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Integrative eQTL-Based Analyses Reveal the Biology of Breast Cancer Risk Loci

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Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease

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Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders

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HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C

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Allele-Specific Up-Regulation of FGFR2 Increases Susceptibility to Breast Cancer

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Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA Expression

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Upregulation of c- MYC in cis through a Large Chromatin Loop Linked to a Cancer Risk-Associated Single-Nucleotide Polymorphism in Colorectal Cancer Cells

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Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus

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Characterization of genome-wide enhancer-promoter interactions reveals co-expression of interacting genes and modes of higher order chromatin organization

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Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo

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The Chromatin Organization Close to SNP rs12913832, Involved in Eye Color Variation, Is Evolutionary Conserved in Vertebrates

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