The cholinergic anti-inflammatory pathway

Inflammation and cancer

Coussens, L. M., & Werb, Z. (2002) · Nature · doi:10.1038/nature01322 · Cited by 15,111 · see citing works

Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation

Wang, H., Yu, M., Ochani, M., Amella, C. A., Tanovic, M., Susarla, S., Li, J. H., Wang, H., Yang, H., Ulloa, L., et al. (2003) · Nature · doi:10.1038/nature01339 · Cited by 3,228 · see citing works

Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis

Wang, H., Liao, H., Ochani, M., Justiniani, M., Lin, X., Yang, L., Al-Abed, Y., Wang, H., Metz, C., Miller, E. J., et al. (2004) · Nature Medicine · doi:10.1038/nm1124 · Cited by 1,170 · see citing works

The cholinergic anti-inflammatory pathway: a missing link in neuroimmunomodulation

Pavlov, V. A., Wang, H., Czura, C. J., Friedman, S. G., & Tracey, K. J. (2003) · Molecular Medicine · doi:10.1007/bf03402177 · Cited by 772 · see citing works

Pharmacological stimulation of the cholinergic antiinflammatory pathway

Bernik, T. R., Friedman, S. G., Ochani, M., DiRaimo, R., Ulloa, L., Yang, H., Sudan, S., Czura, C. J., Ivanova, S. M., & Tracey, K. J. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20011714 · Cited by 529 · see citing works

Central autonomic pathways

Loewy, A. D. (1990) · Central Regulation of Autonomic Functions · doi:10.1093/oso/9780195051063.003.0006 · Cited by 396 · see citing works

Efferent Vagal Fibre Stimulation Blunts Nuclear Factor-κB Activation and Protects Against Hypovolemic Hemorrhagic Shock

Guarini, S., Altavilla, D., Cainazzo, M.-M., Giuliani, D., Bigiani, A., Marini, H., Squadrito, G., Minutoli, L., Bertolini, A., Marini, R., et al. (2003) · Circulation · doi:10.1161/01.cir.0000050627.90734.ed · Cited by 315 · see citing works

Adrenocorticotropin reverses hemorrhagic shock in anesthetized rats through the rapid activation of a vagal anti-inflammatory pathway

GUARINI, S. (2004) · Cardiovascular Research · doi:10.1016/j.cardiores.2004.03.029 · Cited by 131 · see citing works

The Microbiota-Gut-Brain Axis

Cryan, J. F., O'Riordan, K. J., Cowan, C. S. M., Sandhu, K. V., Bastiaanssen, T. F. S., Boehme, M., Codagnone, M. G., Cussotto, S., Fulling, C., Golubeva, A. V., et al. (2019) · Physiological Reviews · doi:10.1152/physrev.00018.2018 · Cited by 5,286 · see citing works

Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression

Miller, A. H., Maletic, V., & Raison, C. L. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.11.029 · Cited by 3,848 · see citing works

Cytokines sing the blues: inflammation and the pathogenesis of depression

Raison, C. L., Capuron, L., & Miller, A. H. (2006) · Trends in Immunology · doi:10.1016/j.it.2005.11.006 · Cited by 3,009 · see citing works

Psychological stress in childhood and susceptibility to the chronic diseases of aging: Moving toward a model of behavioral and biological mechanisms.

Miller, G. E., Chen, E., & Parker, K. J. (2011) · Psychological Bulletin · doi:10.1037/a0024768 · Cited by 1,785 · see citing works

Gut feelings: the emerging biology of gut-brain communication

Mayer, E. A. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3071 · Cited by 1,726 · see citing works

The effects of acute psychological stress on circulating inflammatory factors in humans: a review and meta-analysis

Steptoe, A., Hamer, M., & Chida, Y. (2007) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2007.03.011 · Cited by 1,278 · see citing works

The vagus nerve and the inflammatory reflex – linking immunity and metabolism

Pavlov, V. A., & Tracey, K. J. (2012) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2012.189 · Cited by 1,040 · see citing works

The Effect of Antidepressant Medication Treatment on Serum Levels of Inflammatory Cytokines: A Meta-Analysis

Hannestad, J., DellaGioia, N., & Bloch, M. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.132 · Cited by 914 · see citing works

The effects of acute psychological stress on circulating and stimulated inflammatory markers: a systematic review and meta-analysis

Marsland, A. L., Walsh, C., Lockwood, K., & John-Henderson, N. A. (2017) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2017.01.011 · Cited by 691 · see citing works

Cytokines and their relationship to the symptoms and outcome of cancer

Seruga, B., Zhang, H., Bernstein, L. J., & Tannock, I. F. (2008) · Nature Reviews Cancer · doi:10.1038/nrc2507 · Cited by 652 · see citing works

Central nervous system control of gastrointestinal motility and secretion and modulation of gastrointestinal functions

Browning, K. N., & Travagli, R. A. (2014) · Comprehensive Physiology · doi:10.1002/cphy.c130055 · Cited by 541 · see citing works

Inflammation–Nature's Way to Efficiently Respond to All Types of Challenges: Implications for Understanding and Managing “the Epidemic” of Chronic Diseases

Bennett, J. M., Reeves, G., Billman, G. E., & Sturmberg, J. P. (2018) · Frontiers in Medicine · doi:10.3389/fmed.2018.00316 · Cited by 531 · see citing works

In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression

Kubera, M., Obuchowicz, E., Goehler, L., Brzeszcz, J., & Maes, M. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.08.026 · Cited by 443 · see citing works

Neuroinflammatory processes in Alzheimer’s disease

Heneka, M. T., O’Banion, M. K., Terwel, D., & Kummer, M. P. (2010) · Journal of Neural Transmission · doi:10.1007/s00702-010-0438-z · Cited by 433 · see citing works

Biological markers for anxiety disorders, OCD and PTSD: A consensus statement. Part II: Neurochemistry, neurophysiology and neurocognition

Bandelow, B., Baldwin, D., Abelli, M., Bolea-Alamanac, B., Bourin, M., Chamberlain, S. R., Cinosi, E., Davies, S., Domschke, K., Fineberg, N., et al. (2017) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2016.1190867 · Cited by 347 · see citing works

Stress, the Autonomic Nervous System, and the Immune-kynurenine Pathway in the Etiology of Depression

Won, E., & Kim, Y.-K. (2016) · Current Neuropharmacology · doi:10.2174/1570159x14666151208113006 · Cited by 300 · see citing works

Inflammation-Associated Co-morbidity Between Depression and Cardiovascular Disease

Halaris, A. (2016) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2016_28 · Cited by 233 · see citing works

Psychological adjustment and autonomic disturbances in inflammatory bowel diseases and irritable bowel syndrome

Pellissier, S., Dantzer, C., Canini, F., Mathieu, N., & Bonaz, B. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.10.004 · Cited by 198 · see citing works

A critical review of human endotoxin administration as an experimental paradigm of depression.

DellaGioia, N., & Hannestad, J. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.07.014 · Cited by 175 · see citing works

Conceptual development of the immune system as a sixth sense

Blalock, J. E., & Smith, E. M. (2007) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2006.09.004 · Cited by 153 · see citing works

Exposure to an inflammatory challenge enhances neural sensitivity to negative and positive social feedback.

Muscatell, K. A., Moieni, M., Inagaki, T. K., Dutcher, J. M., Jevtic, I., Breen, E. C., Irwin, M. R., & Eisenberger, N. I. (2016) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2016.03.022 · Cited by 146 · see citing works

Cytokine-induced depression during IFN-α treatment: The role of IL-6 and sleep quality

Prather, A. A., Rabinovitz, M., Pollock, B. G., & Lotrich, F. E. (2009) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2009.07.001 · Cited by 139 · see citing works

Cognitive function is associated with impaired heart rate variability in ageing adults: the Irish longitudinal study on ageing wave one results.

Frewen, J., Finucane, C., Savva, G. M., Boyle, G., Coen, R. F., & Kenny, R. A. (2013) · Clinical Autonomic Research · doi:10.1007/s10286-013-0214-x · Cited by 119 · see citing works

Transient responses of inflammatory cytokines in acute stress.

Yamakawa, K., Matsunaga, M., Isowa, T., Kimura, K., Kasugai, K., Yoneda, M., Kaneko, H., & Ohira, H. (2009) · Biological Psychology · doi:10.1016/j.biopsycho.2009.05.001 · Cited by 107 · see citing works

When couples’ hearts beat together: Synchrony in heart rate variability during conflict predicts heightened inflammation throughout the day

Wilson, S. J., Bailey, B. E., Jaremka, L. M., Fagundes, C. P., Andridge, R., Malarkey, W. B., Gates, K. M., & Kiecolt-Glaser, J. K. (2018) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2018.04.017 · Cited by 88 · see citing works

Injection of amyloid-β to lateral ventricle induces gut microbiota dysbiosis in association with inhibition of cholinergic anti-inflammatory pathways in Alzheimer’s disease

Qian, X.-H., Liu, X.-L., Chen, G., Chen, S.-D., & Tang, H.-D. (2022) · Journal of Neuroinflammation · doi:10.1186/s12974-022-02599-4 · Cited by 56 · see citing works

Is there a role for vagus nerve stimulation therapy as a treatment of traumatic brain injury?

Kumaria, A., & Tolias, C. M. (2012) · British Journal of Neurosurgery · doi:10.3109/02688697.2012.663517 · Cited by 38 · see citing works

Opposing viscerovisceral effects of surgically induced endometriosis and a control abdominal surgery on the rat bladder

Morrison, T. C., Dmitrieva, N., Winnard, K. P., & Berkley, K. J. (2006) · Fertility and Sterility · doi:10.1016/j.fertnstert.2006.03.026 · Cited by 35 · see citing works

New-onset dementia among survivors of pneumonia associated With severe acute respiratory syndrome coronavirus 2 infection

Qureshi, A. I., Baskett, W. I., Huang, W., Naqvi, S. H., & Shyu, C.-R. (2022) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofac115 · Cited by 23 · see citing works

Succumbing to the laws of attraction: Exploring the sometimes pathogenic versatility of discrete immune logic

Fritsch, P., Craddock, T. J., del Rosario, R. M., Rice, M. A., Smylie, A., Folcik, V. A., de Vries, G., Fletcher, M. A., Klimas, N. G., & Broderick, G. (2013) · Systems Biomedicine · doi:10.4161/sysb.28948 · Cited by 16 · see citing works

Heart Rate Variability Predicts Treatment Outcome in Major Depression

(2017) · Journal of Psychiatry and Brain Science · doi:10.20900/jpbs.20170017 · Cited by 13 · see citing works