Cited by 23Memory and Neural MechanismsMemory Processes and InfluencesCognitive Functions and Memory

Extending possible applications of an episodic-like memory task in rats

Barbosa, Flávio Freitas, Pontes, Isabella Maria de Oliveira, Ribeiro, Alessandra Mussi, Silva, Regina Helena·2010·Behavioural Brain Research

Abstract

Recently, an object recognition episodic-like memory task was proposed in rodents. However, the short retention delay of the task narrows its applications. This study verifies whether this task can be evoked after 24h. Additionally, the effect of a classical amnestic agent (scopolamine) on episodic-like memory consolidation was investigated. Rats showed increased exploration of old over recent objects and spent more time exploring displaced over stationary object. Both old over recent and displaced over stationary objects preferences were abolished by pos-training scopolamine administration (1mg/kg i.p.), indicating impaired spatiotemporal retrieval. In conclusion, the object recognition task that accomplishes the what, where and when components of episodic-like memory in rats can persist for 24h.

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Crossref · 10.1016/j.bbr.2009.11.028

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Authors
Barbosa, F. F., Pontes, I. M. D. O., Ribeiro, A. M., & Silva, R. H.
Affiliations
Universidade Federal do Rio Grande do Norte (BR)
Corresponding author
Silva, Regina Helena
Venue
Behavioural Brain Research
Publisher
Elsevier BV
Published
2010-12
Volume
215
Issue
2
Pages
326-331
ISSN
0166-4328 (ISSN-L)
OpenAlex
W2122391906
Cited by
23
References
29
Citations by year
2026: 1 · 2022: 2 · 2021: 1 · 2020: 1 · 2018: 2 · 2017: 1 · 2016: 1 · 2015: 3 · 2014: 3 · 2013: 3 · 2012: 4
FWCI
0.81
Type
journal article
Language
en
Open access
closed
Locations
  • Behavioural Brain Research (publishedVersion)
  • PubMed (publishedVersion)
Funders
Tekes
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
Keywords
episodic-like memory, object recognition memory, memory consolidation, scopolamine, amnesia
MeSH terms
Animals, Exploratory Behavior, Male, Mental Recall, Scopolamine, Time Factors, Rats, Wistar, Rats

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