An Exopolysaccharide (EPS) from a Lactobacillus plantarum BR2 with Potential Benefits for Making Functional Foods
Abstract
A high molecular weight EPS of glucomannan nature was recovered and purified to get an yield of 2.8±0.5g/L from Lb. plantarum BR2 and it displayed potent antioxidant activity with 29.8% radical scavenging activity and 19% total antioxidant capacity. At 100µg/ml concentration, it is capable of inhibiting the alpha amylase activity by 10% and at 300µg/ml, it drastically inhibited the alpha-glucosidase activity by 67% which indicates its antidiabetic potential. More interestingly, at a concentration level of 0.1%, it reduced the cholesterol level by a margin of 45% in an in vitro assay. The sample didn't reveal any cytotoxicity against H9C2 normal cells indicating its potential for safe use as a food additive.
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EPS from fruit-associated Lpb. plantarum BR2 reduced cholesterol by 45% in an in vitro assay.
“similarly, fruit-associated Lpb. plantarum BR2 by 45% [31].”
From Lactic Acid Bacteria Exopolysaccharides Producers: A Sustainable Tool for Functional Foods (2021) · cites this paper as [31]
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- Authors
- Sasikumar, K., Kozhummal Vaikkath, D., Devendra, L., & Nampoothiri, K. M.
- Affiliations
- National Institute for Interdisciplinary Science and Technology (IN)
- Corresponding author
- Nampoothiri, K. Madhavan
- Venue
- Bioresource Technology
- Publisher
- Elsevier BV
- Published
- 2017-10
- Volume
- 241
- Pages
- 1152-1156
- ISSN
- 0960-8524 (ISSN-L)
- OpenAlex
- W2614715581
- Cited by
- 169
- References
- 30
- Citations by year
- 2026: 9 · 2025: 19 · 2024: 20 · 2023: 30 · 2022: 21 · 2021: 25 · 2020: 15 · 2019: 18 · 2018: 10 · 2017: 1
- FWCI
- 13.54
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Bioresource Technology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Council of Scientific and Industrial Research (CSC 0133)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
- Keywords
- exopolysaccharides, Lactobacillus plantarum, glucomannan, antioxidant activity, α-amylase inhibition, α-glucosidase inhibition, antidiabetic potential, cholesterol lowering, functional food ingredients, food additive safety, H9c2 cells
- MeSH terms
- alpha-Glucosidases, Antioxidants, Oxidation-Reduction, Lactobacillus plantarum, Lactiplantibacillus plantarum, Functional Food
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