Soft imperceptible wearable electronics for at-home cardiovascular monitoring of infants with single ventricle heart disease
Abstract
Patients with single ventricle heart disease (SVHD) require multiple palliative surgeries. Due to high mortality rates observed during the four to sixth-month interstage period between the first and second surgery, at-home monitoring practices are important. However, modern-day interstage monitoring does not offer comprehensive quantitative tracking of health conditions since it relies on logging the infant's weight, feeding patterns, and oxygen saturation once a day in a journal. Here, we introduce a soft wearable electronic device for the home monitoring of SVHD patients. The ultrathin, imperceptible, wireless system is designed for safe integration with infants' delicate skin. The system features a chest-mounted biopatch and forehead-mounted pulse oximeter, streaming real-time data to a cloud-based platform. This smart device has built-in alert functions to help caregivers recognize when the patients should be returned to the hospital for in-person observation, easing decision-making from non-clinically trained personnel. In addition, the patient-tailored database also improves the communication between the home and hospital, reducing the load on caretakers during this stressful period.
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Previous wearables for NICU monitoring encounter problems with device longevity, with either single-use or short-term use before replacement.
“Previous wearables have been designed to condense the complicated setups in NICU monitoring into miniaturized wearables for facilitated monitoring4–6; however, they encounter problems with device longevity with either single-use or short-term use before replacement.”
From Soft, all-in-one, nanomembrane wearable system for advancing neonatal health monitoring in Ethiopia (2025) · cites this paper as [4]
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- Authors
- Zhou, L., Aljiffry, A., Lee, Y. J., Matthews, J., Seitter, B., Soltis, I., Huang, Y., Maher, K., & Yeo, W.-H.
- Affiliations
- Georgia Institute of Technology (US)
- Emory University (US)
- Children's Healthcare of Atlanta (US)
- Corresponding author
- Yeo, Woon-Hong
- Venue
- Biosensors and Bioelectronics
- Publisher
- Elsevier BV
- Published
- 2025-06
- Volume
- 278
- Pages
- 117372
- ISSN
- 0956-5663 (ISSN-L)
- OpenAlex
- W4408306492
- Cited by
- 9
- References
- 36
- Citations by year
- 2026: 5 · 2025: 4
- FWCI
- 2.19
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (am, 652 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Locations
- Biosensors and Bioelectronics (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Imlay Foundation
- National Science Foundation (ECCS-2025462)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Physical Sciences › Engineering › Biomedical Engineering › Advanced Sensor and Energy Harvesting Materials
- Health Sciences › Medicine › Epidemiology › Congenital Heart Disease Studies
- Keywords
- single ventricle congenital heart disease, wearable electronics, home monitoring, infants, interstage period, pulse oximetry, wireless health monitoring, cloud data platforms, caregiver notification
- MeSH terms
- Wearable Electronic Devices, Equipment Design, Heart Defects, Congenital, Heart Ventricles, Humans, Infant, Monitoring, Physiologic, Oximetry, Biosensing Techniques, Wireless Technology
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