Formic acid is essential for immunohistochemical detection of aggregated intraneuronal Aβ peptides in mouse models of Alzheimer's disease

The Amyloid Hypothesis of Alzheimer’s Disease: Progress and Problems on the Road to Therapeutics

Hardy, J., & Selkoe, D. J. (2002) · Science · doi:10.1126/science.1072994 · Cited by 13,864 · see citing works

Triple-Transgenic Model of Alzheimer’s Disease with Plaques and Tangles

Oddo, S., Caccamo, A., Shepherd, J. D., Murphy, M. P., Golde, T. E., Kayed, R., Metherate, R., Mattson, M. P., Akbari, Y., & LaFerla, F. M. (2003) · Neuron · doi:10.1016/s0896-6273(03)00434-3 · Cited by 4,126 · see citing works

Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

Oakley, H., Cole, S. L., Logan, S., Maus, E., Shao, P., Craft, J., Guillozet-Bongaarts, A., Ohno, M., Disterhoft, J., Van Eldik, L., et al. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.1202-06.2006 · Cited by 3,530 · see citing works

Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections.

Shi, S., Key, M. E., & Kalra, K. L. (1991) · Journal of Histochemistry & Cytochemistry · doi:10.1177/39.6.1709656 · Cited by 2,587 · see citing works

Thioflavine T interaction with synthetic Alzheimer's disease β ‐amyloid peptides: Detection of amyloid aggregation in solution

LeVine, H. (1993) · Protein Science · doi:10.1002/pro.5560020312 · Cited by 2,268 · see citing works

Intracellular amyloid-β in Alzheimer's disease

LaFerla, F. M., Green, K. N., & Oddo, S. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2168 · Cited by 1,942 · see citing works

Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase

Jankowsky, J. L., Fadale, D. J., Anderson, J., Xu, G. M., Gonzales, V., Jenkins, N. A., Copeland, N. G., Lee, M. K., Younkin, L. H., Wagner, S. L., et al. (2004) · Human Molecular Genetics · doi:10.1093/hmg/ddh019 · Cited by 1,575 · see citing works

Frequent amyloid deposition without significant cognitive impairment among the elderly

Aizenstein, H. J., Nebes, R. D., Saxton, J. A., Price, J. C., Mathis, C. A., Tsopelas, N. D., Ziolko, S. K., James, J. A., Snitz, B. E., Houck, P. R., et al. (2008) · Archives of Neurology · doi:10.1001/archneur.65.11.1509 · Cited by 1,059 · see citing works

Intraneuronal Aβ42 Accumulation in Human Brain

Gouras, G. K., Tsai, J., Naslund, J., Vincent, B., Edgar, M., Checler, F., Greenfield, J. P., Haroutunian, V., Buxbaum, J. D., Xu, H., et al. (2000) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)64700-1 · Cited by 991 · see citing works

Intraneuronal Alzheimer Aβ42 Accumulates in Multivesicular Bodies and Is Associated with Synaptic Pathology

Takahashi, R. H., Milner, T. A., Li, F., Nam, E. E., Edgar, M. A., Yamaguchi, H., Beal, M. F., Xu, H., Greengard, P., & Gouras, G. K. (2002) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)64463-x · Cited by 706 · see citing works

Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice

Guo, Q., Fu, W., Sopher, B. L., Miller, M. W., Ware, C. B., Martin, G. M., & Mattson, M. P. (1999) · Nature Medicine · doi:10.1038/4789 · Cited by 489 · see citing works

Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids.

Kitamoto, T., Ogomori, K., Tateishi, J., & Prusiner, S. B. (1987) · PubMed · Cited by 472 · see citing works

Intracellular accumulation of β-amyloid1–42 in neurons is facilitated by the α7 nicotinic acetylcholine receptor in Alzheimer’s disease

Nagele, R. G., D’Andrea, M. R., Anderson, W. J., & Wang, H.-Y. (2002) · Neuroscience · doi:10.1016/s0306-4522(01)00460-2 · Cited by 456 · see citing works

Alzheimer disease models and human neuropathology: similarities and differences

Duyckaerts, C. J., Potier, M., & Delatour, B. (2007) · Acta Neuropathologica · doi:10.1007/s00401-007-0312-8 · Cited by 441 · see citing works

Massive CA1/2 Neuronal Loss with Intraneuronal and N-Terminal Truncated Aβ42 Accumulation in a Novel Alzheimer Transgenic Model

Casas, C., Sergeant, N., Itier, J.-M., Blanchard, V., Wirths, O., van der Kolk, N., Vingtdeux, V., van de Steeg, E., Ret, G., Canton, T., et al. (2004) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)63388-3 · Cited by 400 · see citing works

Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses

Almeida, C. G., Tampellini, D., Takahashi, R. H., Greengard, P., Lin, M. T., Snyder, E. M., & Gouras, G. K. (2005) · Neurobiology of Disease · doi:10.1016/j.nbd.2005.02.008 · Cited by 397 · see citing works

Evidence that neurones accumulating amyloid can undergo lysis to form amyloid plaques in Alzheimer’s disease

D'Andrea, M. R., Nagele, R. G., Wang, H., Peterson, P. A., & Lee, D. H. S. (2001) · Histopathology · doi:10.1046/j.1365-2559.2001.01082.x · Cited by 390 · see citing works

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation

Chui, D.-H., Tanahashi, H., Ozawa, K., Ikeda, S., Checler, F., Ueda, O., Suzuki, H., Araki, W., Inoue, H., Shirotani, K., et al. (1999) · Nature Medicine · doi:10.1038/8438 · Cited by 364 · see citing works

A modified β‐amyloid hypothesis: intraneuronal accumulation of the β‐amyloid peptide – the first step of a fatal cascade

Wirths, O., Multhaup, G., & Bayer, T. A. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02737.x · Cited by 349 · see citing works

Intraneuronal Aβ accumulation and origin of plaques in Alzheimer's disease

Gouras, G. K., Almeida, C. G., & Takahashi, R. H. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.05.022 · Cited by 338 · see citing works

Intraneuronal Aβ accumulation precedes plaque formation in β-amyloid precursor protein and presenilin-1 double-transgenic mice

Wirths, O., Multhaup, G., Czech, C., Blanchard, V., Moussaoui, S., Tremp, G., Pradier, L., Beyreuther, K., & Bayer, T. A. (2001) · Neuroscience Letters · doi:10.1016/s0304-3940(01)01876-6 · Cited by 336 · see citing works

β-Amyloid Accumulation Impairs Multivesicular Body Sorting by Inhibiting the Ubiquitin-Proteasome System

Almeida, C. G., Takahashi, R. H., & Gouras, G. K. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.5078-05.2006 · Cited by 316 · see citing works

The Arctic Alzheimer mutation facilitates early intraneuronal Aβ aggregation and senile plaque formation in transgenic mice

Lord, A., Kalimo, H., Eckman, C., Zhang, X.-Q., Lannfelt, L., & Nilsson, L. N. G. (2006) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2004.12.007 · Cited by 260 · see citing works

Intracellular Aβ and cognitive deficits precede β-amyloid deposition in transgenic arcAβ mice

Knobloch, M., Konietzko, U., Krebs, D. C., & Nitsch, R. M. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.06.019 · Cited by 259 · see citing works

Intraneuronal Aβ42 accumulation in Down syndrome brain: Original Articles

Mori, C., Spooner, E. T., Wisniewski, K. E., Wisniewski, T. M., Yamaguchi, H., Saido, T. C., Tolan, D. R., Selkoe, D. J., & Lemere, C. A. (2002) · Amyloid · doi:10.3109/13506120208995241 · Cited by 255 · see citing works

Intraneuronal Aβ-Amyloid Precedes Development of Amyloid Plaques in Down Syndrome

Gyure, K. A., Durham, R., Stewart, W. F., Smialek, J. E., & Troncoso, J. C. (2001) · Archives of Pathology & Laboratory Medicine · doi:10.5858/2001-125-0489-iaapdo · Cited by 248 · see citing works

Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta

Pigino, G. F., Morfini, G. A., Atagi, Y., Deshpande, A., Yu, C., Jungbauer, L. M., LaDu, M. J., Busciglio, J. A., & Brady, S. T. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0901229106 · Cited by 226 · see citing works

Intraneuronal pyroglutamate-Abeta 3–42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model

Wirths, O., Breyhan, H., Cynis, H., Schilling, S., Demuth, H.-U., & Bayer, T. A. (2009) · Acta Neuropathologica · doi:10.1007/s00401-009-0557-5 · Cited by 174 · see citing works

Amyloid protein and neurofibrillary tangles coexist in the same neuron in Alzheimer disease.

Grundke, I., Iqbal, K., George, L., Tung, Y. C., Kim, K. S., & Wisniewski, H. M. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.8.2853 · Cited by 142 · see citing works

Transient intraneuronal Aβ rather than extracellular plaque pathology correlates with neuron loss in the frontal cortex of APP/PS1KI mice

Christensen, D. Z., Kraus, S. L., Flohr, A., Cotel, M.-C., Wirths, O., & Bayer, T. A. (2008) · Acta Neuropathologica · doi:10.1007/s00401-008-0451-6 · Cited by 126 · see citing works

Intraneuronal APP/Aβ Trafficking and Plaque Formation in β‐Amyloid Precursor Protein and Presenilin‐1 Transgenic Mice

Wirths, O., Multhaup, G., Czech, C., Feldmann, N., Blanchard, V., Tremp, G., Beyreuther, K., Pradier, L., & Bayer, T. A. (2002) · Brain Pathology · doi:10.1111/j.1750-3639.2002.tb00442.x · Cited by 125 · see citing works

Intra- and extracellular Abeta and PHF in clinically evaluated cases of Alzheimer's disease.

Fernández‐Vizarra, P., Fernández, A. P., Castro‐Blanco, S., Serrano, J., Bentura, M. L., Martínez‐Murillo, R., Martínez, A., & Rodrigo, J. (2004) · PubMed · doi:10.14670/hh-19.823 · Cited by 121 · see citing works

Abnormal distribution of the non-Abeta component of Alzheimer's disease amyloid precursor/alpha-synuclein in Lewy body disease as revealed by proteinase K and formic acid pretreatment.

Takeda, A., Hashimoto, M., Mallory, M. E., Sundsumo, M., Hansen, L., Sisk, A., & Masliah, E. (1998) · PubMed · Cited by 114 · see citing works

Inter-laboratory comparison of neuropathological assessments of β-amyloid protein: a study of the BrainNet Europe consortium

Alafuzoff, I. I., Pikkarainen, M., Arzberger, T., Thal, D. R., Al‐Sarraj, S., Bell, J. E., Bódi, I., Budka, H., Capetillo‐Zarate, E., Ferrer, I., et al. (2008) · Acta Neuropathologica · doi:10.1007/s00401-008-0358-2 · Cited by 105 · see citing works

Mice as models: Transgenic approaches and Alzheimer's disease

Games, D., Buttini, M., Kobayashi, D. T., Schenk, D., & Seubert, P. A. (2006) · Journal of Alzheimer s Disease · doi:10.3233/jad-2006-9s316 · Cited by 91 · see citing works

Intraneuronal Aβ immunoreactivity is not a predictor of brain amyloidosis-β or neurofibrillary degeneration

Węgiel, J., Kuchna, I., Nowicki, K., Frackowiak, J., Mazur‐Kolecka, B., Imaki, H., Wegiel, J., Mehta, P. D., Silverman, W. P., Reisberg, ‌., et al. (2007) · Acta Neuropathologica · doi:10.1007/s00401-006-0191-4 · Cited by 89 · see citing works

APP/PS1KI bigenic mice develop early synaptic deficits and hippocampus atrophy

Breyhan, H., Wirths, O., Duan, K., Marcello, A., Rettig, J., & Bayer, T. A. (2009) · Acta Neuropathologica · doi:10.1007/s00401-009-0539-7 · Cited by 87 · see citing works

Aβ42-positive non-pyramidal neurons around amyloid plaques in Alzheimer's disease

Mochizuki, A., Tamaoka, A., Shimohata, A., Komatsuzaki, Y., & Shoji, S. (2000) · The Lancet · doi:10.1016/s0140-6736(99)04937-5 · Cited by 85 · see citing works

Activation of the human supraptic and paraventricular nucleus neurons with aging and in Alzheimer's disease as judged from increasing size of the Golgi apparatus

Lucassen, P. J., Ravid, R., Gonatas, N. K., & Swaab, D. F. (1993) · Brain Research · doi:10.1016/0006-8993(93)91144-h · Cited by 78 · see citing works

Intracellular Aβ triggers neuron loss in the cholinergic system of the APP/PS1KI mouse model of Alzheimer's disease

Christensen, D. Z., Bayer, T. A., & Wirths, O. (2010) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2008.07.022 · Cited by 77 · see citing works

Consistent immunohistochemical detection of intracellular β-amyloid42 in pyramidal neurons of Alzheimer's disease entorhinal cortex

D’Andrea, M. R., Nagele, R. G., Wang, H.-Y., & Lee, D. H. S. (2002) · Neuroscience Letters · doi:10.1016/s0304-3940(02)00875-3 · Cited by 76 · see citing works

Intraneuronal amyloid β and reduced brain volume in a novel APP T714I mouse model for Alzheimer's disease

Van Broeck, B., Vanhoutte, G., Pirici, D., Van Dam, D., Wils, H., Cuijt, I., Vennekens, K., Zabielski, M., Michalik, A., Theuns, J., et al. (2008) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.10.016 · Cited by 60 · see citing works

Reduced antioxidant enzyme activity in brains of mice transgenic for human presenilin-1 with single or multiple mutations

Leutner, S., Czech, C., Schindowski, K., Touchet, N., Eckert, A., & Müller, W. E. (2000) · Neuroscience Letters · doi:10.1016/s0304-3940(00)01449-x · Cited by 59 · see citing works

Amyloid β-peptide levels in laser capture microdissected cornu ammonis 1 pyramidal neurons of Alzheimer's brain

Aoki, M., Volkmann, I., Tjernberg, L. O., Winblad, B., & Bogdanovic, N. (2008) · NeuroReport · doi:10.1097/wnr.0b013e328302c858 · Cited by 53 · see citing works

Lipofuscin and Aβ42 exhibit distinct distribution patterns in normal and Alzheimer's disease brains

D’Andrea, M. R., Nagele, R. G., Gumula, N. A., Reiser, P. A., Polkovitch, D. A., Hertzog, B. M., & Andrade‐Gordon, P. (2002) · Neuroscience Letters · doi:10.1016/s0304-3940(01)02444-2 · Cited by 53 · see citing works

The use of formic acid to embellish amyloid plaque detection in Alzheimer's disease tissues misguides key observations

D'Andrea, M. R., Reiser, P. A., Polkovitch, D. A., Gumula, N. A., Branchide, B., Hertzog, B. M., Schmidheiser, D., Belkowski, S., Gastard, M. C., & Andrade-Gordon, P. (2003) · Neuroscience Letters · doi:10.1016/s0304-3940(03)00252-0 · Cited by 50 · see citing works

Intraneuronal amyloid β42 enhanced by heating but counteracted by formic acid

Ohyagi, Y., Tsuruta, Y., Motomura, K., Miyoshi, K., Kikuchi, H., Iwaki, T., Taniwaki, T., & Kira, J. (2006) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2006.06.010 · Cited by 33 · see citing works

NMR Identification of the Formic Acid‐Modified Residue in Alzheimer's Amyloid Protein

Klunk, W. E., Xu, C., & Pettegrew, J. W. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.62010349.x · Cited by 20 · see citing works

P1‐026: Intracellular Aβ triggers neuron loss in the cholinergic system of the APP/PS1KI mouse model of Alzheimer's disease

Christensen, D. Z., Bayer, T. A., & Wirths, O. (2008) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2008.05.611 · Cited by 3 · see citing works

Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease

Gouras, G. K., Tampellini, D., Takahashi, R. H., & Capetillo-Zarate, E. (2010) · Acta Neuropathologica · doi:10.1007/s00401-010-0679-9 · Cited by 372 · see citing works

Plaque formation and the intraneuronal accumulation of β‐amyloid in Alzheimer's disease

Takahashi, R. H., Nagao, T., & Gouras, G. K. (2017) · Pathology International · doi:10.1111/pin.12520 · Cited by 354 · see citing works

Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer’s disease models and human brains

Vaillant-Beuchot, L., Mary, A., Pardossi-Piquard, R., Bourgeois, A., Lauritzen, I., Eysert, F., Kinoshita, P. F., Cazareth, J., Badot, C., Fragaki, K., et al. (2021) · Acta Neuropathologica · doi:10.1007/s00401-020-02234-7 · Cited by 263 · see citing works

Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody

Youmans, K. L., Tai, L. M., Kanekiyo, T., Stine Jr, W. B., Michon, S.-C., Nwabuisi-Heath, E., Manelli, A. M., Fu, Y., Riordan, S., Eimer, W. A., et al. (2012) · Molecular Neurodegeneration · doi:10.1186/1750-1326-7-8 · Cited by 164 · see citing works

Early-life stress lastingly alters the neuroinflammatory response to amyloid pathology in an Alzheimer’s disease mouse model

Hoeijmakers, L., Ruigrok, S. R., Amelianchik, A., Ivan, D., van Dam, A.-M., Lucassen, P. J., & Korosi, A. (2017) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2016.12.023 · Cited by 138 · see citing works

Accumulation of intraneuronal Aβ correlates with ApoE4 genotype

Christensen, D. Z., Schneider-Axmann, T., Lucassen, P. J., Bayer, T. A., & Wirths, O. (2010) · Acta Neuropathologica · doi:10.1007/s00401-010-0666-1 · Cited by 120 · see citing works

Prolonged running, not fluoxetine treatment, increases neurogenesis, but does not alter neuropathology, in the 3xTg mouse model of Alzheimer’s disease

Marlatt, M. W., Potter, M. C., Bayer, T. A., van Praag, H., & Lucassen, P. J. (2013) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2012_237 · Cited by 92 · see citing works

Studies for Improving a Rat Model of Alzheimer’s Disease: Icv Administration of Well-Characterized β-Amyloid 1-42 Oligomers Induce Dysfunction in Spatial Memory

Kasza, Á., Penke, B., Frank, Z., Bozsó, Z., Szegedi, V., Hunya, Á. G., Németh, K., Kozma, G., & Fülöp, L. (2017) · Molecules · doi:10.3390/molecules22112007 · Cited by 75 · see citing works

Immunohistochemical Visualization of Amyloid-β Protein Precursor and Amyloid-β in Extra- and Intracellular Compartments in the Human Brain

Aho, L., Pikkarainen, M., Hiltunen, M., Leinonen, V., & Alafuzoff, I. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-091681 · Cited by 71 · see citing works

Peripheral Inflammation, Apolipoprotein E4 , and Amyloid-β Interact to Induce Cognitive and Cerebrovascular Dysfunction

Marottoli, F. M., Katsumata, Y., Koster, K. P., Thomas, R., Fardo, D. W., & Tai, L. M. (2017) · ASN NEURO · doi:10.1177/1759091417719201 · Cited by 68 · see citing works

Cranial irradiation significantly reduces beta amyloid plaques in the brain and improves cognition in a murine model of Alzheimer’s Disease (AD)

Marples, B., McGee, M. C., Callan, S. P., Bowen, S. E., Thibodeau, B. J., Michael, D. B., Wilson, G. D., Maddens, M. E., Fontanesi, J., & Martinez, A. A. (2015) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2015.10.019 · Cited by 60 · see citing works

LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions

Zhao, P., Xu, Y., Jiang, L.-L., Fan, X., Ku, Z., Li, L., Liu, X., Deng, M., Arase, H., Zhu, J.-J., et al. (2022) · Molecular Neurodegeneration · doi:10.1186/s13024-022-00550-y · Cited by 54 · see citing works

Monoclonal Antibody Against the Turn of the 42-Residue Amyloid β-Protein at Positions 22 and 23

Murakami, K., Horikoshi‐Sakuraba, Y., Murata, N., Noda, Y., Masuda, Y., Kinoshita, N., Hatsuta, H., Murayama, S., Shirasawa, T., Shimizu, T., et al. (2010) · ACS Chemical Neuroscience · doi:10.1021/cn100072e · Cited by 50 · see citing works

Neuronal spreading and plaque induction of intracellular Aβ and its disruption of Aβ homeostasis

Roos, T. T., Garcia, M. G., Martinsson, I., Mabrouk, R., Israelsson, B., Deierborg, T., Kobro‐Flatmoen, A., Tanila, H., & Gouras, G. K. (2021) · Acta Neuropathologica · doi:10.1007/s00401-021-02345-9 · Cited by 47 · see citing works

Parvalbumin-Positive Neuron Loss and Amyloid-β Deposits in the Frontal Cortex of Alzheimer’s Disease-Related Mice

Ali, F., Baringer, S. L., Neal, A., Choi, E. Y., & Kwan, A. C. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-181190 · Cited by 43 · see citing works

Treatment with the glutamate modulator riluzole prevents early life stress-induced cognitive deficits and impairments in synaptic plasticity in APPswe/PS1dE9 mice

Lesuis, S. L., Kaplick, P. M., Lucassen, P. J., & Krugers, H. J. (2019) · Neuropharmacology · doi:10.1016/j.neuropharm.2019.02.023 · Cited by 40 · see citing works

Spine pruning in 5xFAD mice starts on basal dendrites of layer 5 pyramidal neurons

Crowe, S. E., & Ellis‐Davies, G. C. R. (2013) · Brain Structure and Function · doi:10.1007/s00429-013-0518-6 · Cited by 38 · see citing works

Early-onset dysfunction of retrosplenial cortex precedes overt amyloid plaque formation in Tg2576 mice

Poirier, G. L., Amin, E., Good, M. A., & Aggleton, J. P. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.11.025 · Cited by 30 · see citing works

Most dystrophic neurites in the common 5xFAD Alzheimer mouse model originate from axon terminals

Mabrouk, R., Miettinen, P. O., & Tanila, H. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106150 · Cited by 27 · see citing works

AβPP Accumulation and/or Intraneuronal Amyloid-β Accumulation? The 3xTg-AD Mouse Model Revisited

Wirths, O., Dins, A., & Bayer, T. A. (2012) · Journal of Alzheimer s Disease · doi:10.3233/jad-2011-111529 · Cited by 26 · see citing works

Early postnatal handling reduces hippocampal amyloid plaque formation and enhances cognitive performance in APPswe/PS1dE9 mice at middle age

Lesuis, S. L., van Hoek, B. A. C. E., Lucassen, P. J., & Krugers, H. J. (2017) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2017.05.016 · Cited by 27 · see citing works

Dissecting α-synuclein inclusion pathology diversity in multiple system atrophy: implications for the prion-like transmission hypothesis

Dhillon, J.-K. S., Trejo‐Lopez, J. A., Riffe, C. J., McFarland, N. R., Hiser, W. M., Giasson, B. I., & Yachnis, A. T. (2019) · Laboratory Investigation · doi:10.1038/s41374-019-0198-9 · Cited by 20 · see citing works

Brainwide distribution and variance of amyloid-beta deposits in tg-ArcSwe mice

Lillehaug, S., Skaaraas, G. H. E. S., Nilsson, L. N. G., Bjaalie, J. G., Leergaard, T. B., & Torp, R. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.09.013 · Cited by 18 · see citing works

Alzheimer's Aβ assembly binds sodium pump and blocks endothelial NOS activity via ROS-PKC pathway in brain vascular endothelial cells

Sasahara, T., Satomura, K., Tada, M., Kakita, A., & Hoshi, M. M. (2021) · iScience · doi:10.1016/j.isci.2021.102936 · Cited by 17 · see citing works

Development of a novel cellular model of Alzheimer’s disease utilizing neurosphere cultures derived from B6C3-Tg(APPswe,PSEN1dE9)85Dbo/J embryonic mouse brain

Ghate, P. S., Sidhar, H., Carlson, G. A., & Giri, R. K. (2014) · SpringerPlus · doi:10.1186/2193-1801-3-161 · Cited by 14 · see citing works

PhIP exposure in rodents produces neuropathology potentially relevant to Alzheimer’s disease

Syeda, T., Foguth, R. M., Llewellyn, E., & Cannon, J. R. (2020) · Toxicology · doi:10.1016/j.tox.2020.152436 · Cited by 15 · see citing works

Repeat-associated non-AUG translation as a common mechanism for the polyGln ataxias

Báñez-Coronel, M., Zu, T., Aldridge, M., Guo, S., Ajredini, R., Morrison, D., Tays, A. B., Duvick, L. A., Pletniková, O., Yachnis, A. T., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116741 · Cited by 7 · see citing works

The age-related slow increase in amyloid pathology in APP.V717I mice activates microglia, but does not alter hippocampal neurogenesis

Hoeijmakers, L., Meerhoff, G. F., de Vries, J. W., Ruigrok, S. R., van Dam, A., LEUVEN, F. V., Kőrösi, A., & Lucassen, P. J. (2017) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2017.09.013 · Cited by 7 · see citing works

Podoplanin-positive cell-derived small extracellular vesicles contribute to cardiac amyloidosis after myocardial infarction

Cimini, M., Hansmann, U. H. E., González, C., Chesney, A. D., Truongcao, M. M., Gao, E., Wang, T., Roy, R., Forte, E., Mallaredy, V., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.115408 · Cited by 5 · see citing works

Amyloids in bladder cancer hijack cancer-related proteins and are positive correlated to tumor stage

Alem, D., García-Laviña, C. X., Garagorry, F., Centurión, D., Farías, J., Pazos-Espinosa, H., Cuitiño-Mendiberry, M. N., Villadóniga, C., Castro‐Sowinski, S., Fló, M., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-88307-7 · Cited by 3 · see citing works

DAPI (4’,6-diamidino-2-phenylindole) as a novel fluorochrome for amyloid staining that binds to β-pleated sheet

Uchida, Y., Mizukawa, M., Kamiya, Y., Shiga, T., Aihara, N., & Kamiie, J. (2025) · Biotechnic & Histochemistry · doi:10.1080/10520295.2025.2552251 · Cited by 1 · see citing works

The Evolution of Immunocytochemistry in the Dissection of Neural Complexity

Merighi, A., & Lossi, L. (2015) · Neuromethods · doi:10.1007/978-1-4939-2313-7_1 · Cited by 1 · see citing works

Amyloid Basis of Alzheimer’s Disease

D’Andrea, M. R. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-804256-4.00001-2

Immunocytochemical Detection of Intraneuronal Aβ Peptides in Mouse Models of Alzheimer’s Disease

Wirths, O., & Saul, A. (2015) · Neuromethods · doi:10.1007/978-1-4939-2313-7_10

Podoplanin Positive Cell-derived Extracellular Vesicles Contribute to Cardiac Amyloidosis After Myocardial InfarctionPreprint

Cimini, M., Hansmann, U. H. E., González, C., Chesney, A. D., Truongcao, M. M., Gao, E., Wang, T., Roy, R., Forte, E., Mallaredy, V., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.28.601297

Additional file 6 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions

Zhao, P., Xu, Y., Jiang, L.-L., Fan, X., Ku, Z., Li, L., Liu, X., Deng, M., Arase, H., Zhu, J.-J., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20098700

Additional file 5 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions

Zhao, P., Xu, Y., Jiang, L.-L., Fan, X., Ku, Z., Li, L., Liu, X., Deng, M., Arase, H., Zhu, J.-J., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20098697

Additional file 3 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions

Zhao, P., Xu, Y., Jiang, L.-L., Fan, X., Ku, Z., Li, L., Liu, X., Deng, M., Arase, H., Zhu, J.-J., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20098691

Additional file 2 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions

Zhao, P., Xu, Y., Jiang, L.-L., Fan, X., Ku, Z., Li, L., Liu, X., Deng, M., Arase, H., Zhu, J.-J., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20098688

Additional file 4 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions

Zhao, P., Xu, Y., Jiang, L.-L., Fan, X., Ku, Z., Li, L., Liu, X., Deng, M., Arase, H., Zhu, J.-J., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20098694

Additional file 10 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions

Zhao, P., Xu, Y., Jiang, L.-L., Fan, X., Ku, Z., Li, L., Liu, X., Deng, M., Arase, H., Zhu, J.-J., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20098679

Additional file 1 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions

Zhao, P., Xu, Y., Jiang, L.-L., Fan, X., Ku, Z., Li, L., Liu, X., Deng, M., Arase, H., Zhu, J.-J., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20098685

Additional file 8 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions

Zhao, P., Xu, Y., Jiang, L.-L., Fan, X., Ku, Z., Li, L., Liu, X., Deng, M., Arase, H., Zhu, J.-J., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20098706

Additional file 7 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions

Zhao, P., Xu, Y., Jiang, L.-L., Fan, X., Ku, Z., Li, L., Liu, X., Deng, M., Arase, H., Zhu, J.-J., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20098703

Additional file 9 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions

Zhao, P., Xu, Y., Jiang, L.-L., Fan, X., Ku, Z., Li, L., Liu, X., Deng, M., Arase, H., Zhu, J.-J., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20098712

Additional file 11 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions

Zhao, P., Xu, Y., Jiang, L.-L., Fan, X., Ku, Z., Li, L., Liu, X., Deng, M., Arase, H., Zhu, J.-J., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20098682

Implications de la signalisation de la protéine kinase activée par l’AMP (AMPK) dans les dysfonctions mitochondriales, la pathologie amyloïde et Tau, et la neuroinflammation dans la maladie d’Alzheimer

Mary, A. (2022) · theses.fr (ABES) · doi:10.70675/868e288ezd237z49c1z866fzf618e1462aab

Intraneuronal amyloid β42 enhanced by heating but counteracted by formic acid

Ohyagi, Y., Tsuruta, Y., Motomura, K., Miyoshi, K., Kikuchi, H., Iwaki, T., Taniwaki, T., & Kira, J. (2006) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2006.06.010 · Cited by 33 · see citing works

Immunocytochemical Detection of Intraneuronal Aβ Peptides in Mouse Models of Alzheimer’s Disease

Wirths, O., & Saul, A. (2015) · Neuromethods · doi:10.1007/978-1-4939-2313-7_10

Enhanced Antigen Retrieval of Amyloid β Immunohistochemistry

Kai, H., Shin, R., Ogino, K., Hatsuta, H., Murayama, S., & Kitamoto, T. (2012) · Journal of Histochemistry & Cytochemistry · doi:10.1369/0022155412456379 · Cited by 30 · see citing works

P2-010 Protection against neuroinflammation and dopamine cell loss by P38 inhibition in vivo

Sunter, D., Swales, A., Vidgeon-Hart, M., Billinton, A., Pugh, P. L., Wadsworth, G., Smith, M. I., Tilling, L. C., & Upton, N. (2004) · Neurobiology of Aging · doi:10.1016/s0197-4580(04)80758-9

Optimization of techniques for the maximal detection and quantification of Alzheimer’s-related neuropathology with digital imaging

Cummings, B. J., Mason, A. J. L., Kim, R. C., Sheu, P. C. ‐., & Anderson, A. J. (2002) · Neurobiology of Aging · doi:10.1016/s0197-4580(01)00316-5 · Cited by 44 · see citing works