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Genetic disruption of zebrafish mab21l1 reveals a conserved role in eye development and affected pathways

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Synthesis of RNA 5′-Azides from 2′-O-Pivaloyloxymethyl-Protected RNAs and Their Reactivity in Azide–Alkyne Cycloaddition Reactions

Warmiński, M., Kowalska, J., & Jemielity, J. (2017) · Organic Letters · doi:10.1021/acs.orglett.7b01591 · Cited by 15

Replacement of oxygen with sulfur on the furanose ring of cyclic dinucleotides enhances the immunostimulatory effect via STING activation

Saito–Tarashima, N., Kinoshita, M., Igata, Y., Kashiwabara, Y., & Minakawa, N. (2021) · RSC Medicinal Chemistry · doi:10.1039/d1md00114k · Cited by 15

G3BP1 enhances cytoplasmic DNA pattern recognition

Wiser, C. L., Kim, B., & Ascano, M. (2018) · Nature Immunology · doi:10.1038/s41590-018-0279-8 · Cited by 15

Phase separation drives tumor pathogenesis and evolution: all roads lead to Rome

Gu, X., Zhuang, A., Yu, J., Chai, P., Jia, R., & Ruan, J. (2022) · Oncogene · doi:10.1038/s41388-022-02195-z · Cited by 15

NF-κB regulates the expression of STING via alternative promoter usage

Chen, L.-Y., Pang, X., Chen, C., & Xu, H. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.121336 · Cited by 15

Phase separation in cGAS-STING signaling

Li, Q., & Gao, P. (2023) · Frontiers of Medicine · doi:10.1007/s11684-023-1026-6 · Cited by 15

The antiviral response triggered by the cGAS/STING pathway is subverted by the foot-and-mouth disease virus proteases

Sanz, M. Á., Polo, M., Rodríguez‐Pulido, M., Ranjitha, H. B., & Sáiz, M. (2024) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-024-05190-7 · Cited by 14

MYO1F positions cGAS on the plasma membrane to ensure full and functional signaling

Wang, H., Cui, Z., Sun, W., Yi, M., Cheng, Y., Zhang, Y., Du, Y., Pan, T., Gao, R., Feng, L., et al. (2024) · Molecular Cell · doi:10.1016/j.molcel.2024.11.026 · Cited by 14

SIRT2 suppresses aging-associated cGAS activation and protects aged mice from severe COVID-19

Barthez, M., Xue, B., Zheng, J., Wang, Y., Song, Z., Mu, W., Wang, C.-L., Guo, J., Yang, F., Ma, Y., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.115562 · Cited by 14

The cGAS-STING axis: a comprehensive review from immune defense to disease pathogenesis

Sood, A. (2025) · Immunologic Research · doi:10.1007/s12026-025-09648-z · Cited by 14

An invertebrate gene encoding a Mab21-containing protein involves in antiviral response through regulating the STING pathway

Li, S., Yang, F., Wang, F., Lv, X., & Li, F. (2021) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2021.104101 · Cited by 14

Modulation of immune responses by DNA damage signaling

Uchihara, Y., Permata, T. B. M., Sato, H., & Shibata, A. (2021) · DNA repair · doi:10.1016/j.dnarep.2021.103135 · Cited by 16

A photoaffinity labeling strategy identified EF1A1 as a binding protein of cyclic dinucleotide 2′3′-cGAMP

Hou, Y., Lu, H., Li, J., Guan, Z., Zhang, J., Zhang, W., Yin, C., Sun, L., Zhang, Y., & Jiang, H. (2021) · Cell chemical biology · doi:10.1016/j.chembiol.2021.08.006 · Cited by 14

Putative role of mitochondria in SARS-CoV-2 mediated brain dysfunctions: a prospect

Maurya, S. K., Baghel, M. S., Gaurav, G., Chaudhary, V., Kaushik, A. K., & Gautam, A. (2022) · Biotechnology and Genetic Engineering Reviews · doi:10.1080/02648725.2022.2108998 · Cited by 14

The proto-oncogene SRC phosphorylates cGAS to inhibit an antitumor immune response

Dunker, W., Zaver, S. A., Pineda, J. M. B., Howard, C. J., Bradley, R. K., & Woodward, J. J. (2023) · JCI Insight · doi:10.1172/jci.insight.167270 · Cited by 14

Efficient Induction of Cytotoxic T Cells by Viral Vector Vaccination Requires STING-Dependent DC Functions

Barnowski, C., Ciupka, G., Tao, R., Jin, L., Busch, D. H., Tao, S., & Drexler, I. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01458 · Cited by 14

Induction of transposable element expression is central to innate sensingPreprint

Rookhuizen, D. C., Bonté, P., Ye, M., Hoyler, T., Gentili, M., Burgdorf, N., Durand, S., Aprahamian, F., Kroemer, G., Manel, N., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.09.10.457789 · Cited by 16

The conserved poxvirus membrane entry-fusion apparatus component OPG147 targets MITA/STING for immune evasion

Yi, X.-M., Li, M., Wang, S.-Y., Wang, S., Ju, Z., Lei, Y.-L., Zhang, Y., Zhu, C., Zhang, Y., Song, J., et al. (2025) · PLoS Pathogens · doi:10.1371/journal.ppat.1013198 · Cited by 13

Cyclic GMP-AMP Synthase (cGAS) is a cytosolic DNA sensor that activates type I interferon pathway by generating a second messenger (P1346)

Sun, L., Wu, J., & Chen, Z. J. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.190.supp.207.2 · Cited by 8

The catalytic mechanism of cyclic GMP‐AMP synthase (cGAS) and implications for innate immunity and inhibition

Hall, J., Ralph, E. C., Shanker, S., Wang, H., Byrnes, L. J., Horst, R., Wong, J., Brault, A. L., Dumlao, D. S., Smith, J. F., et al. (2017) · Protein Science · doi:10.1002/pro.3304 · Cited by 80

Cytosolic DNA sensing unraveled

Panne, D. (2013) · Nature Chemical Biology · doi:10.1038/nchembio.1318 · Cited by 3

Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization

Li, X., Shu, C., Yi, G., Chaton, C. T., Shelton, C. L., Diao, J., Zuo, X., Kao, C. C., Herr, A. B., & Li, P. (2013) · Immunity · doi:10.1016/j.immuni.2013.10.019 · Cited by 681

Abstract B030: Structure-function studies of cytosolic DNA sensing pathway

Gao, P., Ascano, M., Zillinger, T., Barchet, W., Tuschl, T., & Patel, D. J. (2016) · Cancer Immunology Research · doi:10.1158/2326-6074.cricimteatiaacr15-b030