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Mn2+ Directly Activates cGAS and Structural Analysis Suggests Mn2+ Induces a Noncanonical Catalytic Synthesis of 2′3′-cGAMP

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The enemy within: endogenous retroelements and autoimmune disease

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Small molecules targeting the innate immune cGAS‒STING‒TBK1 signaling pathway

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Agonist-Mediated Activation of STING Induces Apoptosis in Malignant B Cells

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Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein α Signaling

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Type I interferon-mediated tumor immunity and its role in immunotherapy

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Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

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G3BP1 promotes DNA binding and activation of cGAS

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A non-canonical cGAS–STING–PERK pathway facilitates the translational program critical for senescence and organ fibrosis

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Activation of innate immune cGAS-STING pathway contributes to Alzheimer’s pathogenesis in 5×FAD mice

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STING inhibitors target the cyclic dinucleotide binding pocket

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Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity

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Trial watch: STING agonists in cancer therapy

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Cytoplasmic DNA: sources, sensing, and role in aging and disease

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Regulation of cGAS–STING signalling and its diversity of cellular outcomes

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Nucleic Acid Immunity

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A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion

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Inhibition of cGAS DNA Sensing by a Herpesvirus Virion Protein

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Cytosolic DNA sensing by cGAS: regulation, function, and human diseases

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Cyclic GMP-AMP Synthase (cGAS) is a cytosolic DNA sensor that activates type I interferon pathway by generating a second messenger (P1346)

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The catalytic mechanism of cyclic GMP‐AMP synthase (cGAS) and implications for innate immunity and inhibition

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Cytosolic DNA sensing unraveled

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Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization

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Abstract B030: Structure-function studies of cytosolic DNA sensing pathway

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