Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

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Items 301–400 of 1,002

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2. The chemistry of Cas9 and its CRISPR colleagues
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3. Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations
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4. DNA stretching induces Cas9 off-target activity
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5. Genome-wide identification of CRISPR/Cas9 off-targets in human genome
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6. Type III CRISPR-Cas immunity: major differences brushed aside
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7. Engineering CRISPR–Cpf1 crRNAs and mRNAs to maximize genome editing efficiency
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8. High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage
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9. Small-molecule control of protein function through Staudinger reduction
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10. An Outlook on Global Regulatory Landscape for Genome-Edited Crops
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11. CRISPR-Cas in Streptococcus pyogenes
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12. Mitigating off-target effects in CRISPR/Cas9-mediated in vivo gene editing
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13. EIGER detector: application in macromolecular crystallography
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14. CRISPR-Cas orthologues and variants: optimizing the repertoire, specificity and delivery of genome engineering tools
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15. Massively parallel kinetic profiling of natural and engineered CRISPR nucleases
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16. The CRISPR/Cas revolution continues: From efficient gene editing for crop breeding to plant synthetic biology
    Jochen Kumlehn, Janine Pietralla, Göetz Hensel, Michael Pacher, Holger Puchta · 2018 · Journal of Integrative Plant Biology
17. CRISPR–Cas applications in agriculture and plant research
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18. CRISPR/Cas-based genome engineering in natural product discovery
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19. Structural basis for substrate recognition and cleavage by the dimerization-dependent CRISPR–Cas12f nuclease
    Renjian Xiao, Zhuang Li, Shukun Wang, Ruijie Han, Leifu Chang · 2021 · Nucleic Acids Research
20. Crossing enhanced and high fidelity SpCas9 nucleases to optimize specificity and cleavage
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21. RNA Strand Displacement Responsive CRISPR/Cas9 System for mRNA Sensing
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22. Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning
    David Ward Taylor, Yifan Zhu, Raymond H.J. Staals, Jack E. Kornfeld, Akeo Shinkai, John van der OOST, Eva Nogales, Jennifer A. Doudna · 2015 · Science
23. Versatile detection with CRISPR/Cas system from applications to challenges
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24. CRISPR-Cas: Converting A Bacterial Defence Mechanism into A State-of-the-Art Genetic Manipulation Tool
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25. Efficient delivery of nuclease proteins for genome editing in human stem cells and primary cells
    Jia Liu, Thomas Gaj, Yifeng Yang, Nan Wang, Sailan Shui, Sojung Kim, Chidananda Nagamangala Kanchiswamy, Jin‐Soo Kim, Carlos F. Barbas · 2015 · Nature Protocols
26. Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States
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27. Allosteric Motions of the CRISPR–Cas9 HNH Nuclease Probed by NMR and Molecular Dynamics
    Kyle W. East, Jocelyn C. Newton, Uriel N. Morzan, Yogesh B. Narkhede, Atanu Acharya, Erin Skeens, G. Jogl, Víctor S. Batista, Giulia Palermo, George P. Lisi · 2019 · Journal of the American Chemical Society
28. CRISPR/Cas9‐mediated genome editing: From basic research to translational medicine
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29. Inhibition of RNA-binding proteins with small molecules
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30. Single-Stranded DNA Cleavage by Divergent CRISPR-Cas9 Enzymes
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31. NmeCas9 is an intrinsically high-fidelity genome-editing platform
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32. Cut Site Selection by the Two Nuclease Domains of the Cas9 RNA-guided Endonuclease
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33. A Cas9 with PAM recognition for adenine dinucleotides
    Pranam Chatterjee, Jooyoung Lee, Lisa Nip, Sabrina Koseki, Emma Tysinger, Erik J. Sontheimer, Joseph M. Jacobson, Noah Jakimo · 2020 · Nature Communications
34. Protospacer adjacent motif (PAM)-distal sequences engage CRISPR Cas9 DNA target cleavage
    Cencic, Regina, Miura, Hisashi, Malina, Abba, Robert, Francis, Ethier, Sylvain, Schmeing, T. Martin, Dostie, Josée, Pelletier, Jerry · 2014 · PLoS ONE
35. Key role of the REC lobe during CRISPR–Cas9 activation by ‘sensing’, ‘regulating’, and ‘locking’ the catalytic HNH domain
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36. A Single-Chain Photoswitchable CRISPR-Cas9 Architecture for Light-Inducible Gene Editing and Transcription
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37. Engineering cell signaling using tunable CRISPR–Cpf1-based transcription factors
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38. Comprehensive, integrated, and phased whole-genome analysis of the primary ENCODE cell line K562
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39. Cas9-catalyzed DNA Cleavage Generates Staggered Ends: Evidence from Molecular Dynamics Simulations
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40. Characterizing the activity of abundant, diverse and active CRISPR-Cas systems in lactobacilli
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41. Efficient chromosomal gene modification with CRISPR/cas9 and PCR-based homologous recombination donors in cultured Drosophila cells
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42. Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection
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43. A ‘new lease of life’: FnCpf1 possesses DNA cleavage activity for genome editing in human cells
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44. Broad-spectrum enzymatic inhibition of CRISPR-Cas12a
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45. Heavily and fully modified RNAs guide efficient SpyCas9-mediated genome editing
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46. Genome editing by natural and engineered CRISPR-associated nucleases
    Wen Y. Wu, Joyce H.G. Lebbink, Roland Kanaar, Niels Geijsen, John van der OOST · 2018 · Nature Chemical Biology
47. Precision Control of CRISPR-Cas9 Using Small Molecules and Light
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48. Evaluation and Reduction of CRISPR Off-Target Cleavage Events
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49. A new age in functional genomics using CRISPR/Cas9 in arrayed library screening
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50. Efficient generation of mice carrying homozygous double-floxp alleles using the Cas9-Avidin/Biotin-donor DNA system
    Ming Ma, Fengfeng Zhuang, Xiongbing Hu, Bolun Wang, Xianzi Wen, Jiafu Ji, Jianzhong Xi · 2017 · Cell Research
51. In Vitro Enzymology of Cas9
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52. CRISPR Modeling and Correction of Cardiovascular Disease
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53. CUT-PCR: CRISPR-mediated, ultrasensitive detection of target DNA using PCR
    S H Lee, Jihyeon Yu, G-H Hwang, Sang‐Tae Kim, H S Kim, S Ye, Kyoungmi Kim, Juhee Park, D Y Park, Y-K Cho et al. · 2017 · Oncogene
54. Material solutions for delivery of CRISPR/Cas-based genome editing tools: Current status and future outlook
    Tao Yu Wan, Dong Niu, Chuanbin Wu, Fu‐Jian Xu, George McDonald Church, Ping Yuan · 2019 · Materials Today
55. Reduced thermal tolerance in a coral carrying CRISPR-induced mutations in the gene for a heat-shock transcription factor
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56. PE-Designer and PE-Analyzer: web-based design and analysis tools for CRISPR prime editing
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57. Improved genome editing by an engineered CRISPR-Cas12a
    Ma, Enbo, Chen, Kai, Shi, Honglue, Stahl, Elizabeth C, Adler, Ben, Trinidad, Marena, Liu, Junjie, Zhou, Kaihong, Ye, Jinjuan, Doudna, Jennifer A · 2022 · Nucleic Acids Research
58. Diversity of CRISPR-Cas immune systems and molecular machines
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59. Control of Mosquito-Borne Infectious Diseases: Sex and Gene Drive
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60. Structural roles of guide RNAs in the nuclease activity of Cas9 endonuclease
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61. Hybridization Kinetics Explains CRISPR-Cas Off-Targeting Rules
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62. Engineering of temperature- and light-switchable Cas9 variants
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63. Zinc Fingers, TALEs, and CRISPR Systems: A Comparison of Tools for Epigenome Editing
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64. Genome editing for horticultural crop improvement
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65. Current and future prospects for CRISPR‐based tools in bacteria
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66. Nucleosomes Inhibit Cas9 Endonuclease Activity in Vitro
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67. RNA-Independent DNA Cleavage Activities of Cas9 and Cas12a
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68. CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks
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69. Advances in Clustered, Regularly Interspaced Short Palindromic Repeats (CRISPR)-Based Diagnostic Assays Assisted by Micro/Nanotechnologies
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70. How specific is CRISPR/Cas9 really?
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71. Creating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery
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72. A Biophysical Model of CRISPR/Cas9 Activity for Rational Design of Genome Editing and Gene Regulation
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73. CRISPR/Cas9 therapeutics: a cure for cancer and other genetic diseases
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79. Enhanced Cas12a editing in mammalian cells and zebrafish
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84. Genome editing: the road of CRISPR/Cas9 from bench to clinic
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85. Two HEPN domains dictate CRISPR RNA maturation and target cleavage in Cas13d
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86. Challenges Facing CRISPR/Cas9-Based Genome Editing in Plants
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    Park, Hyo Min, Liu, Hui, Wu, Joann, Chong, Anthony, Mackley, Vanessa, Fellmann, Christof, Rao, Anirudh, Jiang, Fuguo, Chu, Hunghao, Murthy, Niren et al. · 2018 · Nature Communications
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