Comprehensive Integration of Single-Cell Data

Stuart, Tim, Butler, Andrew, Hoffman, Paul, Hafemeister, Christoph, Papalexi, Efthymia, Mauck, William M., Hao, Yuhan, Stoeckius, Marlon +2 more·2019·Cell

Cited by (497)

Items 101–200 of 497

  1. Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer’s disease pathology
    Mathys, Hansruedi, Peng, Zhuyu, Boix, Carles A., Victor, Matheus B., Leary, Noelle, Babu, Sudhagar, Abdelhady, Ghada, Jiang, Xueqiao, Ng, Ayesha P., Ghafari, Kimia et al. · 2023 · Cell
  2. Single-cell transcriptomics reveals cell-type-specific diversification in human heart failure
    Koenig, Andrew L., Shchukina, Irina, Amrute, Junedh, Andhey, Prabhakar S., Zaitsev, Konstantin, Lai, Lulu, Bajpai, Geetika, Bredemeyer, Andrea, Smith, Gabriella, Jones, Cameran et al. · 2022 · Nature Cardiovascular Research
  3. Integrated Single-Cell Atlas of Endothelial Cells of the Human Lung
    Schupp, Jonas C., Adams, Taylor S., Cosme, Carlos, Raredon, Micha Sam Brickman, Yuan, Yifan, Omote, Norihito, Poli, Sergio, Chioccioli, Maurizio, Rose, Kadi-Ann, Manning, Edward P. et al. · 2021 · Circulation
  4. Autism genes converge on asynchronous development of shared neuron classes
    Paulsen, Bruna, Velasco, Silvia, Kedaigle, Amanda J., Pigoni, Martina, Quadrato, Giorgia, Deo, Anthony J., Adiconis, Xian, Uzquiano, Ana, Sartore, Rafaela, Yang, Sung Min et al. · 2022 · Nature
  5. Hair-bearing human skin generated entirely from pluripotent stem cells
    Lee, Jiyoon, Rabbani, Cyrus C., Gao, Hongyu, Steinhart, Matthew R., Woodruff, Benjamin M., Pflum, Zachary E., Kim, Alexander, Heller, Stefan, Liu, Yunlong, Shipchandler, Taha Z. et al. · 2020 · Nature
  6. Single-cell CUT&Tag profiles histone modifications and transcription factors in complex tissues
    Bartosovic, Marek, Kabbe, Mukund, Castelo-Branco, Gonçalo · 2021 · Nature Biotechnology
  7. Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders
    Brioschi, Simone, Wang, Wei-Le, Peng, Vincent, Wang, Meng, Shchukina, Irina, Greenberg, Zev J., Bando, Jennifer K., Jaeger, Natalia, Czepielewski, Rafael S., Swain, Amanda et al. · 2021 · Science
  8. Microglia use TAM receptors to detect and engulf amyloid β plaques
    Huang, Youtong, Happonen, Kaisa E., Burrola, Patrick G., O’Connor, Carolyn, Hah, Nasun, Huang, Ling, Nimmerjahn, Axel, Lemke, Greg · 2021 · Nature Immunology
  9. Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease
    Depp, Constanze, Sun, Ting, Sasmita, Andrew Octavian, Spieth, Lena, Berghoff, Stefan A., Nazarenko, Taisiia, Overhoff, Katharina, Steixner-Kumar, Agnes A., Subramanian, Swati, Arinrad, Sahab et al. · 2023 · Nature
  10. Computational principles and challenges in single-cell data integration
    Argelaguet, Ricard, Cuomo, Anna S. E., Stegle, Oliver, Marioni, John C. · 2021 · Nature Biotechnology
  11. Molecular logic of cellular diversification in the mouse cerebral cortex
    Di Bella, Daniela J., Habibi, Ehsan, Stickels, Robert R., Scalia, Gabriele, Brown, Juliana, Yadollahpour, Payman, Yang, Sung Min, Abbate, Catherine, Biancalani, Tommaso, Macosko, Evan Z. et al. · 2021 · Nature
  12. Comprehensive analysis of single cell ATAC-seq data with SnapATAC
    Fang, Rongxin, Preissl, Sebastian, Li, Yang, Hou, Xiaomeng, Lucero, Jacinta, Wang, Xinxin, Motamedi, Amir, Shiau, Andrew K., Zhou, Xinzhu, Xie, Fangming et al. · 2021 · Nature Communications
  13. Benchmarking spatial and single-cell transcriptomics integration methods for transcript distribution prediction and cell type deconvolution
    Li, Bin, Zhang, Wen, Guo, Chuang, Xu, Hao, Li, Longfei, Fang, Minghao, Hu, Yinlei, Zhang, Xinye, Yao, Xinfeng, Tang, Meifang et al. · 2022 · Nature Methods
  14. Microbial metabolite enhances immunotherapy efficacy by modulating T cell stemness in pan-cancer
    Jia, Dingjiacheng, Wang, Qiwen, Qi, Yadong, Jiang, Yao, He, Jiamin, Lin, Yifeng, Sun, Yong, Xu, Jilei, Chen, Wenwen, Fan, Lina et al. · 2024 · Cell
  15. Spatial deconvolution of HER2-positive breast cancer delineates tumor-associated cell type interactions
    Andersson, Alma, Larsson, Ludvig, Stenbeck, Linnea, Salmén, Fredrik, Ehinger, Anna, Wu, Sunny Z., Al-Eryani, Ghamdan, Roden, Daniel, Swarbrick, Alex, Borg, Åke et al. · 2021 · Nature Communications
  16. Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy
    Da Mesquita, Sandro, Papadopoulos, Zachary, Dykstra, Taitea, Brase, Logan, Farias, Fabiana Geraldo, Wall, Morgan, Jiang, Hong, Kodira, Chinnappa Dilip, de Lima, Kalil Alves, Herz, Jasmin et al. · 2021 · Nature
  17. The Power of Plasticity—Metabolic Regulation of Hepatic Stellate Cells
    Trivedi, Parth, Wang, Shuang, Friedman, Scott L. · 2021 · Cell Metabolism
  18. Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease
    Gerrits, Emma, Brouwer, Nieske, Kooistra, Susanne M., Woodbury, Maya E., Vermeiren, Yannick, Lambourne, Mirjam, Mulder, Jan, Kummer, Markus, Möller, Thomas, Biber, Knut et al. · 2021 · Acta Neuropathologica
  19. Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain
    Marsh, Samuel E., Walker, Alec J., Kamath, Tushar, Dissing-Olesen, Lasse, Hammond, Timothy R., de Soysa, T. Yvanka, Young, Adam M. H., Murphy, Sarah, Abdulraouf, Abdulraouf, Nadaf, Naeem et al. · 2022 · Nature Neuroscience
  20. Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction
    Katsura, Hiroaki, Sontake, Vishwaraj, Tata, Aleksandra, Kobayashi, Yoshihiko, Edwards, Caitlin E., Heaton, Brook E., Konkimalla, Arvind, Asakura, Takanori, Mikami, Yu, Fritch, Ethan J. et al. · 2020 · Cell Stem Cell
  21. Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations
    Affo, Silvia, Nair, Ajay, Brundu, Francesco, Ravichandra, Aashreya, Bhattacharjee, Sonakshi, Matsuda, Michitaka, Chin, LiKang, Filliol, Aveline, Wen, Wen, Song, Xinhua et al. · 2021 · Cancer Cell
  22. High-plex protein and whole transcriptome co-mapping at cellular resolution with spatial CITE-seq
    Liu, Yang, DiStasio, Marcello, Su, Graham, Asashima, Hiromitsu, Enninful, Archibald, Qin, Xiaoyu, Deng, Yanxiang, Nam, Jungmin, Gao, Fu, Bordignon, Pino et al. · 2023 · Nature Biotechnology
  23. Spatial profiling of chromatin accessibility in mouse and human tissues
    Deng, Yanxiang, Bartosovic, Marek, Ma, Sai, Zhang, Di, Kukanja, Petra, Xiao, Yang, Su, Graham, Liu, Yang, Qin, Xiaoyu, Rosoklija, Gorazd B. et al. · 2022 · Nature
  24. Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease.
    Sadick, Jessica S., O’Dea, Michael R., Hasel, Philip, Dykstra, Taitea, Faustin, Arline, Liddelow, Shane A. · 2022 · Neuron
  25. A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex
    Yao, Zizhen, Liu, Hanqing, Xie, Fangming, Fischer, Stephan, Adkins, Ricky S., Aldridge, Andrew I., Ament, Seth A., Bartlett, Anna, Behrens, M. Margarita, Van den Berge, Koen et al. · 2021 · Nature
  26. Spatial-CUT&Tag: Spatially resolved chromatin modification profiling at the cellular level
    Deng, Yanxiang, Bartosovic, Marek, Kukanja, Petra, Zhang, Di, Liu, Yang, Su, Graham, Enninful, Archibald, Bai, Zhiliang, Castelo-Branco, Gonçalo, Fan, Rong · 2022 · Science
  27. Chemical reprogramming of human somatic cells to pluripotent stem cells.
    Guan, Jingyang, Wang, Guan, Wang, Jinlin, Zhang, Zhengyuan, Fu, Yao, Cheng, Lin, Meng, Gaofan, Lyu, Yulin, Zhu, Jialiang, Li, Yanqin et al. · 2022 · Nature
  28. Local and systemic responses to SARS-CoV-2 infection in children and adults
    Yoshida, Masahiro, Worlock, Kaylee B., Huang, Ni, Lindeboom, Rik G. H., Butler, Colin R., Kumasaka, Natsuhiko, Dominguez Conde, Cecilia, Mamanova, Lira, Bolt, Liam, Richardson, Laura et al. · 2022 · Nature
  29. Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition
    Pasciuto, Emanuela, Burton, Oliver T., Roca, Carlos P., Lagou, Vasiliki, Rajan, Wenson D., Theys, Tom, Mancuso, Renzo, Tito, Raul Y., Kouser, Lubna, Callaerts-Vegh, Zsuzsanna et al. · 2020 · Cell
  30. Dual ontogeny of disease-associated microglia and disease inflammatory macrophages in aging and neurodegeneration
    Silvin, Aymeric, Uderhardt, Stefan, Piot, Cecile, Da Mesquita, Sandro, Yang, Katharine, Geirsdottir, Laufey, Mulder, Kevin, Eyal, David, Liu, Zhaoyuan, Bridlance, Cecile et al. · 2022 · Immunity
  31. <i>Enterococcus</i> peptidoglycan remodeling promotes checkpoint inhibitor cancer immunotherapy
    Griffin, Matthew E., Espinosa, Juliel, Becker, Jessica L., Luo, Ji-Dung, Carroll, Thomas S., Jha, Jyoti K., Fanger, Gary R., Hang, Howard C. · 2021 · Science
  32. The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis
    Han, Lu, Wu, Yongxia, Fang, Kun, Sweeney, Sean, Roesner, Ulyss K., Parrish, Melodie, Patel, Khushbu, Walter, Tom, Piermattei, Julia, Trimboli, Anthony et al. · 2023 · Nature Communications
  33. Single-cell proteomics enabled by next-generation sequencing or mass spectrometry
    Bennett, Hayley M., Stephenson, William, Rose, Christopher M., Darmanis, Spyros · 2023 · Nature Methods
  34. The triumphs and limitations of computational methods for scRNA-seq
    Kharchenko, Peter V. · 2021 · Nature Methods
  35. Spatiotemporal single-cell analysis of gene expression in the mouse suprachiasmatic nucleus
    Wen, Shao’ang, Ma, Danyi, Zhao, Meng, Xie, Lucheng, Wu, Qingqin, Gou, Lingfeng, Zhu, Chuanzhen, Fan, Yuqi, Wang, Haifang, Yan, Jun · 2020 · Nature Neuroscience
  36. Single-cell epigenomic analyses implicate candidate causal variants at inherited risk loci for Alzheimer’s and Parkinson’s diseases
    Corces, M. Ryan, Shcherbina, Anna, Kundu, Soumya, Gloudemans, Michael J., Frésard, Laure, Granja, Jeffrey M., Louie, Bryan H., Eulalio, Tiffany, Shams, Shadi, Bagdatli, S. Tansu et al. · 2020 · Nature Genetics
  37. Microbial single-cell RNA sequencing by split-pool barcoding
    Kuchina, Anna, Brettner, Leandra M., Paleologu, Luana, Roco, Charles M., Rosenberg, Alexander B., Carignano, Alberto, Kibler, Ryan, Hirano, Matthew, DePaolo, R. William, Seelig, Georg · 2021 · Science
  38. T cells specific for α-myosin drive immunotherapy-related myocarditis
    Axelrod, Margaret L., Meijers, Wouter C., Screever, Elles M., Qin, Juan, Carroll, Mary Grace, Sun, Xiaopeng, Tannous, Elie, Zhang, Yueli, Sugiura, Ayaka, Taylor, Brandie C. et al. · 2022 · Nature
  39. Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Human Developmental Hematopoiesis
    Ranzoni, Anna Maria, Tangherloni, Andrea, Berest, Ivan, Riva, Simone Giovanni, Myers, Brynelle, Strzelecka, Paulina M., Xu, Jiarui, Panada, Elisa, Mohorianu, Irina, Zaugg, Judith B. et al. · 2021 · Cell Stem Cell
  40. A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
    Ahern, David J., Ai, Zhichao, Ainsworth, Mark, Allan, Chris, Allcock, Alice, Angus, Brian, Ansari, M. Azim, Arancibia-Cárcamo, Carolina V., Aschenbrenner, Dominik, Attar, Moustafa et al. · 2022 · Cell
  41. The enteric nervous system relays psychological stress to intestinal inflammation
    Schneider, Kai Markus, Blank, Niklas, Alvarez, Yelina, Thum, Katharina, Lundgren, Patrick, Litichevskiy, Lev, Sleeman, Madeleine, Bahnsen, Klaas, Kim, Jihee, Kardo, Simon et al. · 2023 · Cell
  42. Maturation and persistence of the anti-SARS-CoV-2 memory B cell response
    Sokal, Aurélien, Chappert, Pascal, Barba-Spaeth, Giovanna, Roeser, Anais, Fourati, Slim, Azzaoui, Imane, Vandenberghe, Alexis, Fernandez, Ignacio, Meola, Annalisa, Bouvier-Alias, Magali et al. · 2021 · Cell
  43. Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes
    Sanmarco, Liliana M., Wheeler, Michael A., Gutiérrez-Vázquez, Cristina, Polonio, Carolina Manganeli, Linnerbauer, Mathias, Pinho-Ribeiro, Felipe A., Li, Zhaorong, Giovannoni, Federico, Batterman, Katelyn V., Scalisi, Giulia et al. · 2021 · Nature
  44. Human germinal centres engage memory and naive B cells after influenza vaccination
    Turner, Jackson S., Zhou, Julian Q., Han, Julianna, Schmitz, Aaron J., Rizk, Amena A., Alsoussi, Wafaa B., Lei, Tingting, Amor, Mostafa, McIntire, Katherine M., Meade, Philip et al. · 2020 · Nature
  45. Inferring and perturbing cell fate regulomes in human brain organoids
    Fleck, Jonas Simon, Jansen, Sophie Martina Johanna, Wollny, Damian, Zenk, Fides, Seimiya, Makiko, Jain, Akanksha, Okamoto, Ryoko, Santel, Malgorzata, He, Zhisong, Camp, J. Gray et al. · 2023 · Nature
  46. Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia
    Wang, Chao, Xiong, Monica, Gratuze, Maud, Bao, Xin, Shi, Yang, Andhey, Prabhakar Sairam, Manis, Melissa, Schroeder, Caitlin, Yin, Zhuoran, Madore, Charlotte et al. · 2021 · Neuron
  47. Somatic mutations and cell identity linked by Genotyping of Transcriptomes
    Nam, Anna S., Kim, Kyu-Tae, Chaligne, Ronan, Izzo, Franco, Ang, Chelston, Taylor, Justin, Myers, Robert M., Abu-Zeinah, Ghaith, Brand, Ryan, Omans, Nathaniel D. et al. · 2019 · Nature
  48. Alignment and integration of spatial transcriptomics data
    Zeira, Ron, Land, Max, Strzalkowski, Alexander, Raphael, Benjamin J. · 2022 · Nature Methods
  49. Single-Nucleus RNA-Seq Is Not Suitable for Detection of Microglial Activation Genes in Humans
    Thrupp, Nicola, Sala Frigerio, Carlo, Wolfs, Leen, Skene, Nathan G., Fattorelli, Nicola, Poovathingal, Suresh, Fourne, Yannick, Matthews, Paul M., Theys, Tom, Mancuso, Renzo et al. · 2020 · Cell Reports
  50. Single-cell transcriptional profiles in human skeletal muscle
    Rubenstein, Aliza B., Smith, Gregory R., Raue, Ulrika, Begue, Gwénaëlle, Minchev, Kiril, Ruf-Zamojski, Frederique, Nair, Venugopalan D., Wang, Xingyu, Zhou, Lan, Zaslavsky, Elena et al. · 2020 · Scientific Reports
  51. Single-cell and spatial transcriptomics: deciphering brain complexity in health and disease
    Piwecka, Monika, Rajewsky, Nikolaus, Rybak-Wolf, Agnieszka · 2023 · Nature Reviews Neurology
  52. Microbiota-specific T follicular helper cells drive tertiary lymphoid structures and anti-tumor immunity against colorectal cancer
    Overacre-Delgoffe, Abigail E., Bumgarner, Hannah J., Cillo, Anthony R., Burr, Ansen H.P., Tometich, Justin T., Bhattacharjee, Amrita, Bruno, Tullia C., Vignali, Dario A.A., Hand, Timothy W. · 2021 · Immunity
  53. Predicting cellular responses to complex perturbations in high‐throughput screens
    Lotfollahi, Mohammad, Klimovskaia Susmelj, Anna, De Donno, Carlo, Hetzel, Leon, Ji, Yuge, Ibarra, Ignacio L, Srivatsan, Sanjay R, Naghipourfar, Mohsen, Daza, Riza M, Martin, Beth et al. · 2023 · Molecular Systems Biology
  54. The neurons that restore walking after paralysis
    Kathe, Claudia, Skinnider, Michael A., Hutson, Thomas H., Regazzi, Nicola, Gautier, Matthieu, Demesmaeker, Robin, Komi, Salif, Ceto, Steven, James, Nicholas D., Cho, Newton et al. · 2022 · Nature
  55. Capturing Cardiogenesis in Gastruloids
    Rossi, Giuliana, Broguiere, Nicolas, Miyamoto, Matthew, Boni, Andrea, Guiet, Romain, Girgin, Mehmet, Kelly, Robert G., Kwon, Chulan, Lutolf, Matthias P. · 2021 · Cell Stem Cell
  56. Impaired death receptor signaling in leukemia causes antigen-independent resistance by inducing CAR T-cell dysfunction
    Singh, Nathan, Lee, Yong Gu, Shestova, Olga, Ravikumar, Pranali, Hayer, Katharina E., Hong, Seok Jae, Lu, Xueqing Maggie, Pajarillo, Raymone, Agarwal, Sangya, Kuramitsu, Shunichiro et al. · 2020 · Cancer Discovery
  57. γδ T cells are effectors of immunotherapy in cancers with HLA class I defects
    de Vries, Natasja L., van de Haar, Joris, Veninga, Vivien, Chalabi, Myriam, Ijsselsteijn, Marieke E., van der Ploeg, Manon, van den Bulk, Jitske, Ruano, Dina, van den Berg, Jose G., Haanen, John B. et al. · 2023 · Nature
  58. Single-cell meta-analyses reveal responses of tumor-reactive CXCL13+ T cells to immune-checkpoint blockade
    Liu, Baolin, Zhang, Yuanyuan, Wang, Dongfang, Hu, Xueda, Zhang, Zemin · 2022 · Nature Cancer
  59. Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells
    Franjic, Daniel, Skarica, Mario, Ma, Shaojie, Arellano, Jon I., Tebbenkamp, Andrew T.N., Choi, Jinmyung, Xu, Chuan, Li, Qian, Morozov, Yury M., Andrijevic, David et al. · 2022 · Neuron
  60. Bacterial droplet-based single-cell RNA-seq reveals antibiotic-associated heterogeneous cellular states
    Ma, Peijun, Amemiya, Haley M., He, Lorrie L., Gandhi, Shivam J., Nicol, Robert, Bhattacharyya, Roby P., Smillie, Christopher S., Hung, Deborah T. · 2023 · Cell
  61. Single-cell transcriptomes and whole-brain projections of serotonin neurons in the mouse dorsal and median raphe nuclei
    Ren, Jing, Isakova, Alina, Friedmann, Drew, Zeng, Jiawei, Grutzner, Sophie M, Pun, Albert, Zhao, Grace Q, Kolluru, Sai Saroja, Wang, Ruiyu, Lin, Rui et al. · 2019 · eLife
  62. Joint profiling of histone modifications and transcriptome in single cells from mouse brain
    Zhu, Chenxu, Zhang, Yanxiao, Li, Yang Eric, Lucero, Jacinta, Behrens, M. Margarita, Ren, Bing · 2021 · Nature Methods
  63. Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology
    Lee, Seung-Hye, Meilandt, William J., Xie, Luke, Gandham, Vineela D., Ngu, Hai, Barck, Kai H., Rezzonico, Mitchell G., Imperio, Jose, Lalehzadeh, Guita, Huntley, Melanie A. et al. · 2021 · Neuron
  64. Integrative multi-omics approaches in cancer research: from biological networks to clinical subtypes
    Heo, Yong Jin, Hwa, Chanwoong, Lee, Gang-Hee, Park, Jae-Min, An, Joon-Yong · 2021 · Molecules and Cells
  65. Novel Alzheimer risk genes determine the microglia response to amyloid-β but not to TAU pathology
    Sierksma, Annerieke, Lu, Ashley, Mancuso, Renzo, Fattorelli, Nicola, Thrupp, Nicola, Salta, Evgenia, Zoco, Jesus, Blum, David, Buée, Luc, De Strooper, Bart et al. · 2020 · EMBO Molecular Medicine
  66. Tau Activation of Microglial cGAS–IFN Reduces MEF2C‐mediated Cognitive Resilience
    Udeochu, Joe C., Amin, Sadaf, Huang, Yige, Fan, Li, Torres, Eileen Ruth S., Carling, Gillian K., Liu, Bangyan, McGurran, Hugo, Coronas-Samano, Guillermo, Kauwe, Grant et al. · 2023 · Nature Neuroscience
  67. SARS-CoV-2 receptor and entry genes are expressed by sustentacular cells in the human olfactory neuroepithelium
    Fodoulian, Leon, Tuberosa, Joel, Rossier, Daniel, Boillat, Madlaina, Kan, Chenda, Pauli, Véronique, Egervari, Kristof, Lobrinus, Johannes A., Landis, Basile N., Carleton, Alan et al. · 2020
  68. Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing
    Mahmoudi, Salah, Mancini, Elena, Xu, Lucy, Moore, Alessandra, Jahanbani, Fereshteh, Hebestreit, Katja, Srinivasan, Rajini, Li, Xiyan, Devarajan, Keerthana, Prélot, Laurie et al. · 2019 · Nature
  69. Human neocortical expansion involves glutamatergic neuron diversification
    Berg, Jim, Sorensen, Staci A., Ting, Jonathan T., Miller, Jeremy A., Chartrand, Thomas, Buchin, Anatoly, Bakken, Trygve E., Budzillo, Agata, Dee, Nick, Ding, Song-Lin et al. · 2021 · Nature
  70. Single-cell brain organoid screening identifies developmental defects in autism
    Li, Chong, Fleck, Jonas Simon, Martins-Costa, Catarina, Burkard, Thomas R., Themann, Jan, Stuempflen, Marlene, Peer, Angela Maria, Vertesy, Ábel, Littleboy, Jamie B., Esk, Christopher et al. · 2023 · Nature
  71. Single-cell sequencing techniques from individual to multiomics analyses
    Kashima, Yukie, Sakamoto, Yoshitaka, Kaneko, Keiya, Seki, Masahide, Suzuki, Yutaka, Suzuki, Ayako · 2020 · Experimental &amp; Molecular Medicine
  72. Three-dimensional human alveolar stem cell culture models reveal infection response to SARS-CoV-2
    Youk, Jeonghwan, Kim, Taewoo, Evans, Kelly V., Jeong, Young-Il, Hur, Yongsuk, Hong, Seon Pyo, Kim, Je Hyoung, Yi, Kijong, Kim, Su Yeon, Na, Kwon Joong et al. · 2020 · Cell Stem Cell
  73. BANKSY unifies cell typing and tissue domain segmentation for scalable spatial omics data analysis
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  74. Transplantation of chemically induced pluripotent stem-cell-derived islets under abdominal anterior rectus sheath in a type 1 diabetes patient.
    Wang, Shusen, Du, Yuanyuan, Zhang, Boya, Meng, Gaofan, Liu, Zewen, Liew, Soon Yi, Liang, Rui, Zhang, Zhengyuan, Cai, Xiangheng, Wu, Shuangshuang et al. · 2024 · Cell
  75. Neuronal diversity and convergence in a visual system developmental atlas
    Özel, Mehmet Neset, Simon, Félix, Jafari, Shadi, Holguera, Isabel, Chen, Yen-Chung, Benhra, Najate, El-Danaf, Rana Naja, Kapuralin, Katarina, Malin, Jennifer Amy, Konstantinides, Nikolaos et al. · 2021 · Nature
  76. Targeted Perturb-seq enables genome-scale genetic screens in single cells
    Schraivogel, Daniel, Gschwind, Andreas R., Milbank, Jennifer H., Leonce, Daniel R., Jakob, Petra, Mathur, Lukas, Korbel, Jan O., Merten, Christoph A., Velten, Lars, Steinmetz, Lars M. · 2020 · Nature Methods
  77. Conservation and divergence of cortical cell organization in human and mouse revealed by MERFISH
    Fang, Rongxin, Xia, Chenglong, Close, Jennie L., Zhang, Meng, He, Jiang, Huang, Zhengkai, Halpern, Aaron R., Long, Brian, Miller, Jeremy A., Lein, Ed S. et al. · 2022 · Science
  78. Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion
    Frangieh, Chris J., Melms, Johannes C., Thakore, Pratiksha I., Geiger-Schuller, Kathryn R., Ho, Patricia, Luoma, Adrienne M., Cleary, Brian, Jerby-Arnon, Livnat, Malu, Shruti, Cuoco, Michael S. et al. · 2021 · Nature Genetics
  79. The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer
    Freed-Pastor, William A., Lambert, Laurens J., Ely, Zackery A., Pattada, Nimisha B., Bhutkar, Arjun, Eng, George, Mercer, Kim L., Garcia, Ana P., Lin, Lin, Rideout, William M. et al. · 2021 · Cancer Cell
  80. DestVI identifies continuums of cell types in spatial transcriptomics data
    Lopez, Romain, Li, Baoguo, Keren-Shaul, Hadas, Boyeau, Pierre, Kedmi, Merav, Pilzer, David, Jelinski, Adam, Yofe, Ido, David, Eyal, Wagner, Allon et al. · 2022 · Nature Biotechnology
  81. SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2
    Amanat, Fatima, Thapa, Mahima, Lei, Tinting, Ahmed, Shaza M. Sayed, Adelsberg, Daniel C., Carreño, Juan Manuel, Strohmeier, Shirin, Schmitz, Aaron J., Zafar, Sarah, Zhou, Julian Q. et al. · 2021 · Cell
  82. Spatially resolved single-cell genomics and transcriptomics by imaging
    Zhuang, Xiaowei · 2021 · Nature Methods
  83. Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases
    de Klein, Niek, Tsai, Ellen A., Vochteloo, Martijn, Baird, Denis, Huang, Yunfeng, Chen, Chia-Yen, van Dam, Sipko, Oelen, Roy, Deelen, Patrick, Bakker, Olivier B. et al. · 2023 · Nature Genetics
  84. Novel antigen-presenting cell imparts Treg-dependent tolerance to gut microbiota
    Akagbosu, Blossom, Tayyebi, Zakieh, Shibu, Gayathri, Paucar Iza, Yoselin A., Deep, Deeksha, Parisotto, Yollanda Franco, Fisher, Logan, Pasolli, H. Amalia, Thevin, Valentin, Elmentaite, Rasa et al. · 2022 · Nature
  85. Single-cell technologies in hepatology: new insights into liver biology and disease pathogenesis
    Ramachandran, Prakash, Matchett, Kylie P., Dobie, Ross, Wilson-Kanamori, John R., Henderson, Neil C. · 2020 · Nature Reviews Gastroenterology &amp; Hepatology
  86. Cell type prioritization in single-cell data
    Skinnider, Michael A., Squair, Jordan W., Kathe, Claudia, Anderson, Mark A., Gautier, Matthieu, Matson, Kaya J. E., Milano, Marco, Hutson, Thomas H., Barraud, Quentin, Phillips, Aaron A. et al. · 2021 · Nature Biotechnology
  87. HypoMap—a unified single-cell gene expression atlas of the murine hypothalamus
    Steuernagel, Lukas, Lam, Brian Y. H., Klemm, Paul, Dowsett, Georgina K. C., Bauder, Corinna A., Tadross, John A., Hitschfeld, Tamara Sotelo, del Rio Martin, Almudena, Chen, Weiyi, de Solis, Alain J. et al. · 2022 · Nature Metabolism
  88. Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity
    Schnell, Alexandra, Huang, Linglin, Singer, Meromit, Singaraju, Anvita, Barilla, Rocky M., Regan, Brianna M.L., Bollhagen, Alina, Thakore, Pratiksha I., Dionne, Danielle, Delorey, Toni M. et al. · 2021 · Cell
  89. Characterizing the molecular regulation of inhibitory immune checkpoints with multimodal single-cell screens
    Papalexi, Efthymia, Mimitou, Eleni P., Butler, Andrew W., Foster, Samantha, Bracken, Bernadette, Mauck, William M., Wessels, Hans-Hermann, Hao, Yuhan, Yeung, Bertrand Z., Smibert, Peter et al. · 2021 · Nature Genetics
  90. Simultaneous trimodal single-cell measurement of transcripts, epitopes, and chromatin accessibility using TEA-seq
    Swanson, Elliott, Lord, Cara, Reading, Julian, Heubeck, Alexander T, Genge, Palak C, Thomson, Zachary, Weiss, Morgan DA, Li, Xiao-jun, Savage, Adam K, Green, Richard R et al. · 2021 · eLife
  91. Single-Cell Sequencing of Brain Cell Transcriptomes and Epigenomes
    Armand, Ethan J., Li, Junhao, Xie, Fangming, Luo, Chongyuan, Mukamel, Eran A. · 2021 · Neuron
  92. Single-cell transcriptomic analyses of the developing meninges reveal meningeal fibroblast diversity and function.
    DeSisto, John, O’Rourke, Rebecca, Jones, Hannah E., Pawlikowski, Bradley, Malek, Alexandra D., Bonney, Stephanie, Guimiot, Fabien, Jones, Kenneth L., Siegenthaler, Julie A. · 2020 · Developmental Cell
  93. Multimodal analysis of cell types in a hypothalamic node controlling social behavior
    Kim, Dong-Wook, Yao, Zizhen, Graybuck, Lucas T., Kim, Tae Kyung, Nguyen, Thuc Nghi, Smith, Kimberly A., Fong, Olivia, Yi, Lynn, Koulena, Noushin, Pierson, Nico et al. · 2019 · Cell
  94. Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells
    Cañellas-Socias, Adrià, Cortina, Carme, Hernando-Momblona, Xavier, Palomo-Ponce, Sergio, Mulholland, Eoghan J., Turon, Gemma, Mateo, Lidia, Conti, Sefora, Roman, Olga, Sevillano, Marta et al. · 2022 · Nature
  95. ApoE isoform– and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy
    Seo, Dong-oh, O’Donnell, David, Jain, Nimansha, Ulrich, Jason D., Herz, Jasmin, Li, Yuhao, Lemieux, Mackenzie, Cheng, Jiye, Hu, Hao, Serrano, Javier R. et al. · 2023 · Science
  96. A harmonized atlas of mouse spinal cord cell types and their spatial organization
    Russ, Daniel E., Cross, Ryan B. Patterson, Li, Li, Koch, Stephanie C., Matson, Kaya J. E., Yadav, Archana, Alkaslasi, Mor R., Lee, Dylan I., Le Pichon, Claire E., Menon, Vilas et al. · 2021 · Nature Communications
  97. Single-nucleus RNA-seq and FISH identify coordinated transcriptional activity in mammalian myofibers
    Dos Santos, Matthieu, Backer, Stéphanie, Saintpierre, Benjamin, Izac, Brigitte, Andrieu, Muriel, Letourneur, Franck, Relaix, Frederic, Sotiropoulos, Athanassia, Maire, Pascal · 2020 · Nature Communications
  98. Single-cell analysis of olfactory neurogenesis and differentiation in adult humans
    Durante, Michael A., Kurtenbach, Stefan, Sargi, Zoukaa B., Harbour, J. William, Choi, Rhea, Kurtenbach, Sarah, Goss, Garrett M., Matsunami, Hiroaki, Goldstein, Bradley J. · 2020 · Nature Neuroscience
  99. Big data in basic and translational cancer research
    Jiang, Peng, Sinha, Sanju, Aldape, Kenneth, Hannenhalli, Sridhar, Sahinalp, Cenk, Ruppin, Eytan · 2022 · Nature Reviews Cancer
  100. Human neural tube morphogenesis in vitro by geometric constraints
    Karzbrun, Eyal, Khankhel, Aimal H., Megale, Heitor C., Glasauer, Stella M. K., Wyle, Yofiel, Britton, George, Warmflash, Aryeh, Kosik, Kenneth S., Siggia, Eric D., Shraiman, Boris I. et al. · 2021 · Nature