Cited by 288Dementia and Cognitive Impairment ResearchCancer-related cognitive impairment studiesNeurological Disease Mechanisms and Treatments

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Risk Factors for the Progression of Mild Cognitive Impairment to Dementia

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Abstract

The increasing prevalence of cognitive impairment among the older adult population warrants attention to the identification of practices that may minimize the progression of early forms of cognitive impairment, including the transitional stage of mild cognitive impairment (MCI), to permanent stages of dementia. This article identifies both markers of disease progress and risk factors linked to the progression of MCI to dementia. Potentially modifiable risk factors may offer researchers a point of intervention to modify the effect of the risk factor and to minimize the future burden of dementia.

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Crossref · 10.1016/j.cger.2013.07.009

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  • The study adjusted for confounders associated with both exposure and outcome, identified based on literature review and clinical knowledge.

    “We adjusted for confounders associated with both the exposure and the outcome, which were identified based on the literature review and clinical knowledge [19–21].”

    From Association between first-line antidepressant use and risk of dementia in older adults: a retrospective cohort study (2023) · cites this paper as [19]

    The Summary identifies the paper as a review of risk factors for progression from MCI to dementia, so it could inform the citing authors’ literature-based choice of variables. The Comorbidity and Other Clinical Characteristics section describes adjustments made in another study, but does not say that this review adjusted for confounders or that the citing authors selected variables associated with both their exposure and outcome using clinical knowledge. In the citing sentence, “We adjusted” describes the citing authors’ own method, not this source’s. (LLM, conf=0.77)

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Metadata

Authors
Campbell, N. L., Unverzagt, F., LaMantia, M. A., Khan, B. A., & Boustani, M. A.
Affiliations
  • Regenstrief Institute (US)
  • Indiana University School of Medicine (US)
Corresponding author
Campbell, Noll L.
Venue
Clinics in Geriatric Medicine
Publisher
Elsevier BV
Published
2013-11
Volume
29
Issue
4
Pages
873-893
ISSN
0749-0690 (ISSN-L)
OpenAlex
W2012603004
Cited by
288
References
14
Citations by year
2026: 35 · 2025: 48 · 2024: 46 · 2023: 49 · 2022: 40 · 2021: 17 · 2020: 16 · 2019: 12 · 2018: 6 · 2017: 3 · 2016: 9 · 2015: 1 · 2014: 6
FWCI
0.60
Type
journal article
Language
en
Open access
Locations
  • Clinics in Geriatric Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
  • IUScholarWorks (Indiana University) (submittedVersion)
  • PMC
Funders
  • Agency for Healthcare Research and Quality (R01HS019818-01, R01HS019818)
  • National Institute on Aging (K23AG043476)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Health Sciences › Medicine › Oncology › Cancer-related cognitive impairment studies
  • Life Sciences › Neuroscience › Neurology › Neurological Disease Mechanisms and Treatments
Keywords
mild cognitive impairment, dementia progression, risk factors, disease progression biomarkers, modifiable risk factors, dementia prevention, older adults, cognitive impairment
MeSH terms
Aged, Dementia, Humans, Risk Factors, Disease Progression, Cognitive Dysfunction

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