The Gut Microbiota Regulates Intestinal CD4 T Cells Expressing RORγt and Controls Metabolic Disease

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Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice

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Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

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The intestinal microbiota fuelling metabolic inflammation

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High-Fat, Western-Style Diet, Systemic Inflammation, and Gut Microbiota: A Narrative Review

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GPCR-Mediated Signaling of Metabolites

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The Treg/Th17 Axis: A Dynamic Balance Regulated by the Gut Microbiome

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The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome

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Obesity and diabetes as high‐risk factors for severe coronavirus disease 2019 ( Covid ‐19)

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Obesity, Inflammation, and Immune System in Osteoarthritis

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The Intestinal Immune System in Obesity and Insulin Resistance

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Role of the Gut Microbiome in the Pathogenesis of Obesity and Obesity-Related Metabolic Dysfunction

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Role of the gut microbiota in host appetite control: bacterial growth to animal feeding behaviour

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The dichotomous nature of T helper 17 cells

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Lipocalin-2: A Master Mediator of Intestinal and Metabolic Inflammation

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Diabetes, infection risk and COVID-19

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Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome

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Gut Microbiota: An Important Player in Type 2 Diabetes Mellitus

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Obesity-Induced TNFα and IL-6 Signaling: The Missing Link between Obesity and Inflammation—Driven Liver and Colorectal Cancers

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Tissue Immune Cells Fuel Obesity-Associated Inflammation in Adipose Tissue and Beyond

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Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health

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A Specific Gut Microbiota Dysbiosis of Type 2 Diabetic Mice Induces GLP-1 Resistance through an Enteric NO-Dependent and Gut-Brain Axis Mechanism

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The gut microbiome in Alzheimer’s disease: what we know and what remains to be explored

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Gut Microbial Dysbiosis in the Pathogenesis of Gastrointestinal Dysmotility and Metabolic Disorders

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The Alterations in and the Role of the Th17/Treg Balance in Metabolic Diseases

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Cytotoxic and regulatory roles of mucosal-associated invariant T cells in type 1 diabetes

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Linking the Microbiota, Chronic Disease, and the Immune System

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The role of T cells in age-related diseases

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Changes in blood microbiota profiles associated with liver fibrosis in obese patients: A pilot analysis

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Role of T Lymphocytes in Type 2 Diabetes and Diabetes-Associated Inflammation

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Gut Microbiota–Derived Short-Chain Fatty Acids Promote Prostate Cancer Growth via IGF1 Signaling

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Gut Microbiota Dysbiosis Drives and Implies Novel Therapeutic Strategies for Diabetes Mellitus and Related Metabolic Diseases

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Colonic Pro-inflammatory Macrophages Cause Insulin Resistance in an Intestinal Ccl2/Ccr2-Dependent Manner

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Gut-associated IgA+ immune cells regulate obesity-related insulin resistance

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Microbiota in T-cell homeostasis and inflammatory diseases

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Gut microbiota and immune crosstalk in metabolic disease

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Oxidative Stress and Low-Grade Inflammation in Polycystic Ovary Syndrome: Controversies and New Insights

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Regionalized Development and Maintenance of the Intestinal Adaptive Immune Landscape

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The role of diet and intestinal microbiota in the development of metabolic syndrome

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Probiotic with or without Fiber Controls Body Fat Mass, Associated with Serum Zonulin, in Overweight and Obese Adults—Randomized Controlled Trial

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Kaempferol reduces obesity, prevents intestinal inflammation, and modulates gut microbiota in high-fat diet mice

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Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity

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Alteration in the Gut Microbiota Provokes Susceptibility to Tuberculosis

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Adipose Tissue-Resident Immune Cells in Obesity and Type 2 Diabetes

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Gut microbiota directs PPARγ‐driven reprogramming of the liver circadian clock by nutritional challenge

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Bacteroides uniformis combined with fiber amplifies metabolic and immune benefits in obese mice

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Emerging concepts in intestinal immune control of obesity-related metabolic disease

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Intestinal microbiota and the immune system in metabolic diseases

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Adaptive immune cells shape obesity-associated type 2 diabetes mellitus and less prominent comorbidities

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Gestational diabetes is associated with changes in placental microbiota and microbiome

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Berberine Attenuates Intestinal Mucosal Barrier Dysfunction in Type 2 Diabetic Rats

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Gut-Specific Delivery of T-Helper 17 Cells Reduces Obesity and Insulin Resistance in Mice

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The Gut Microbiome as Therapeutic Target in Central Nervous System Diseases: Implications for Stroke

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Gut dysbiosis and impairment of immune system homeostasis in perinatally-exposed mice to Bisphenol A precede obese phenotype development

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T Cell Populations and Functions Are Altered in Human Obesity and Type 2 Diabetes

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Palmitic acid damages gut epithelium integrity and initiates inflammatory cytokine production

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Th17 and Treg lymphocytes in obesity and Type 2 diabetic patients

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Fecal and blood microbiota profiles and presence of nonalcoholic fatty liver disease in obese versus lean subjects

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Microbiota and Diabetes Mellitus: Role of Lipid Mediators

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Are gut dysbiosis, barrier disruption, and endotoxemia related to adipose tissue dysfunction in metabolic disorders? Overview of the mechanisms involved

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Mitochondrial function in intestinal epithelium homeostasis and modulation in diet-induced obesity

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Identification of gut microbiota and microbial metabolites regulated by an antimicrobial peptide lipocalin 2 in high fat diet-induced obesity

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Rutin and Its Combination With Inulin Attenuate Gut Dysbiosis, the Inflammatory Status and Endoplasmic Reticulum Stress in Paneth Cells of Obese Mice Induced by High-Fat Diet

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Nutrition Regulates Innate Immunity in Health and Disease

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The gut microbiota mediates protective immunity against tuberculosis via modulation of lncRNA

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The intestinal immune system and gut barrier function in obesity and ageing

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Crosstalk between γδ T cells and the microbiota

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The Role of Leukocytes in Diabetic Cardiomyopathy

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The cholesterol metabolite 25-hydroxycholesterol restrains the transcriptional regulator SREBP2 and limits intestinal IgA plasma cell differentiation

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Holdemanella biformis improves glucose tolerance and regulates GLP‐1 signaling in obese mice

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Gut microbiota and associated metabolites: key players in high-fat diet-induced chronic diseases

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Interleukin‐17/interleukin‐17 receptor axis elicits intestinal neutrophil migration, restrains gut dysbiosis and lipopolysaccharide translocation in high‐fat diet‐induced metabolic syndrome model

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Bifidobacterium animalis subsp. lactis 420 for Metabolic Health: Review of the Research

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Intestinal Barrier Function and Immune Homeostasis Are Missing Links in Obesity and Type 2 Diabetes Development

Riedel, S., Pheiffer, C., Johnson, R., Louw, J., & Muller, C. J. F. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.833544 · Cited by 78

Bifidobacterium adolescentis Is Effective in Relieving Type 2 Diabetes and May Be Related to Its Dominant Core Genome and Gut Microbiota Modulation Capacity

Qian, X., Si, Q., Lin, G., Zhu, M., Lu, J., Zhang, H., Wang, G., & Chen, W. (2022) · Nutrients · doi:10.3390/nu14122479 · Cited by 72

Metabolic regulation of the Th17/Treg balance in inflammatory bowel disease

Zhang, S., Zhong, R., Tang, S., Chen, L., & Zhang, H. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107184 · Cited by 76

Bacteroides uniformis CECT 7771 alleviates inflammation within the gut-adipose tissue axis involving TLR5 signaling in obese mice

Fabersani, E., Portune, K. J., Campillo, I., López‐Almela, I., la Paz, S. M., Romaní‐Pérez, M., Benítez‐Páez, A., & Sanz, Y. (2021) · Scientific Reports · doi:10.1038/s41598-021-90888-y · Cited by 73

The Role of T Cells in Obesity-Associated Inflammation and Metabolic Disease

Park, C., & Shastri, N. (2022) · Immune Network · doi:10.4110/in.2022.22.e13 · Cited by 76

Probiotic B420 and prebiotic polydextrose improve efficacy of antidiabetic drugs in mice

Stenman, L. K., Waget, A., Garret, C., Briand, F., Burcelin, R., Sulpice, T., & Lahtinen, S. J. (2015) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-015-0075-7 · Cited by 68

Aryl hydrocarbon receptor agonist indigo protects against obesity-related insulin resistance through modulation of intestinal and metabolic tissue immunity

Lin, Y., Luck, H., Khan, S. M., Schneeberger, P. H. H., Tsai, S. J., Clemente‐Casares, X., Lei, H., Leu, Y., Chan, Y. T., Chen, H., et al. (2019) · International Journal of Obesity · doi:10.1038/s41366-019-0340-1 · Cited by 73

Natural Polyphenols: A Potential Therapeutic Approach to Hypoglycemia

Zhao, C., Wan, X., Zhou, S. D., & Cao, H. (2020) · eFood · doi:10.2991/efood.k.200302.001 · Cited by 66

Bifidobacteria attenuate the development of metabolic disorders, with inter- and intra-species differences

Zhu, G., Ma, F., Wang, G., Wang, Y., Zhao, J., Zhang, H., & Chen, W. (2018) · Food & Function · doi:10.1039/c8fo00100f · Cited by 63

The Functional Stability of FOXP3 and RORγt in Treg and Th17 and Their Therapeutic Applications

Ren, J., & Li, B. (2016) · Advances in protein chemistry and structural biology · doi:10.1016/bs.apcsb.2016.10.002 · Cited by 66

Ursolic Acid Improves Intestinal Damage and Bacterial Dysbiosis in Liver Fibrosis Mice

Wan, S., Liu, C., Huang, C., Luo, F., & Zhu, X. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01321 · Cited by 60

Circadian Rhythms in Adipose Tissue Physiology

Kiehn, J., Tsang, A. H. K., Heyde, I., Leinweber, B., Kolbe, I., Leliavski, A., & Oster, H. (2017) · Comprehensive physiology · doi:10.1002/cphy.c160017 · Cited by 64

T helper 17 (Th17) cell responses to the gut microbiota in human diseases

Sun, C., Yang, N. Y., Zheng, Z., Liu, D., & Xu, Q. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.114483 · Cited by 60

Wheat Consumption Aggravates Colitis in Mice via Amylase Trypsin Inhibitor–mediated Dysbiosis

Pickert, G., Wirtz, S. J., Matzner, J., Ashfaq–Khan, M., Heck, R., Rosigkeit, S., Thies, D., Surabattula, R., Ehmann, D., Wehkamp, J., et al. (2020) · Gastroenterology · doi:10.1053/j.gastro.2020.03.064 · Cited by 60

Gut Microbiota and IL-17A: Physiological and Pathological Responses

Douzandeh-Mobarrez, B., & Kariminik, A. (2017) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-017-9329-z · Cited by 60

Triggering the adaptive immune system with commensal gut bacteria protects against insulin resistance and dysglycemia

Pomié, C., Blasco‐Baqué, V., Klopp, P., Nicolas, S., Waget, A., Loubières, P., Azalbert, V., Puel, A., Lopez, F., Dray, C., et al. (2016) · Molecular Metabolism · doi:10.1016/j.molmet.2016.03.004 · Cited by 57

Different Th17 immunity in gut, liver, and adipose tissues during obesity: the role of diet, genetics, and microbes

Cavallari, J. F., Denou, E., Foley, K. P., Khan, W. I., & Schertzer, J. D. (2016) · Gut Microbes · doi:10.1080/19490976.2015.1127481 · Cited by 55

Obese Subjects With Specific Gustatory Papillae Microbiota and Salivary Cues Display an Impairment to Sense Lipids

Besnard, P., Christensen, J. E., Brignot, H., Bernard, A., Passilly‐Degrace, P., Nicklaus, S., de Barros, J.-P. P., Collet, X., Lelouvier, B., Servant, F., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-24619-1 · Cited by 55

Transfer of dysbiotic gut microbiota has beneficial effects on host liver metabolism

Nicolas, S., Blasco‐Baqué, V., Fournel, A., Gilleron, J., Klopp, P., Waget, A., Ceppo, F., Marlin, A., Padmanabhan, R., Iacovoni, J. S., et al. (2017) · Molecular Systems Biology · doi:10.15252/msb.20167356 · Cited by 60

Green tea polyphenol epigallocatechin-3-gallate alleviates nonalcoholic fatty liver disease and ameliorates intestinal immunity in mice fed a high-fat diet

Huang, J., Li, W., Liao, W., Hao, Q., Tang, D., Wang, D., Wang, Y., & Ge, G. (2020) · Food & Function · doi:10.1039/d0fo02152k · Cited by 51

Intestinal Th17 Cells Regulate Metabolic Homeostasis by Controlling Gut Microbiota

Kim, Y. (2018)

The gut microbiome: a novel cardio-metabolic target?

Patel, J. (2019) · Cardiovascular Research · doi:10.1093/cvr/cvz151 · Cited by 2

Microbiotas from Humans with Inflammatory Bowel Disease Alter the Balance of Gut Th17 and RORγt+ Regulatory T Cells and Exacerbate Colitis in Mice

Britton, G. J., Contijoch, E. J., Mogno, I., Vennaro, O. H., Llewellyn, S. R., Ng, R., Li, Z., Mortha, A., Merad, M., Das, A., et al. (2019) · Immunity · doi:10.1016/j.immuni.2018.12.015 · Cited by 549

Regulation of metabolic homeostasis by intestinal Th17 cells

Kim, Y. (2018)

Cutting Edge: Intestinal IL-17A Receptor Signaling Specifically Regulates High-Fat Diet–Mediated, Microbiota-Driven Metabolic Disorders

Gaudino, S. J., Huang, H., Jean-Pierre, M., Joshi, P., Beaupre, M., Kempen, C. G., Wong, H. T., & Kumar, P. (2021) · The Journal of Immunology · doi:10.4049/jimmunol.2000986 · Cited by 10