Sex differences in pain responses

Sex, gender, and pain: a review of recent clinical and experimental findings

Fillingim, R. B., King, C. D., Ribeiro-Dasilva, M. C., Rahim-Williams, B., & Riley, J. L. (2009) · The Journal of Pain · doi:10.1016/j.jpain.2008.12.001 · Cited by 2,766 · see citing works

Policy: NIH to balance sex in cell and animal studies

Clayton, J. A., & Collins, F. S. (2014) · Nature · doi:10.1038/509282a · Cited by 1,816 · see citing works

Sex bias in neuroscience and biomedical research

Beery, A. K., & Zucker, I. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.07.002 · Cited by 1,763 · see citing works

P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

Tsuda, M., Shigemoto‐Mogami, Y., Koizumi, S., Mizokoshi, A., Kohsaka, S., Salter, M. W., & Inoue, K. (2003) · Nature · doi:10.1038/nature01786 · Cited by 1,567 · see citing works

Gender variations in clinical pain experience

Unruh, A. M. (1996) · Pain · doi:10.1016/0304-3959(95)00214-6 · Cited by 1,550 · see citing works

Different immune cells mediate mechanical pain hypersensitivity in male and female mice

Sorge, R. E., Mapplebeck, J. C. S., Rosen, S., Beggs, S., Taves, S., Alexander, J. K., Martin, L. J., Austin, J.-S., Sotocinal, S. G., Chen, D., et al. (2015) · Nature Neuroscience · doi:10.1038/nn.4053 · Cited by 1,442 · see citing works

Sex differences in pain

Berkley, K. J. (1997) · Behavioral and Brain Sciences · doi:10.1017/s0140525x97221485 · Cited by 1,125 · see citing works

Glial activation: a driving force for pathological pain

Watkins, L. R., Milligan, E. D., & Maier, S. F. (2001) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01854-3 · Cited by 1,091 · see citing works

Sex differences in pain and pain inhibition: multiple explanations of a controversial phenomenon

Mogil, J. S. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3360 · Cited by 1,065 · see citing works

Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway

Lehnardt, S., Massillon, L., Follett, P., Jensen, F. E., Ratan, R., Rosenberg, P. A., Volpe, J. J., & Vartanian, T. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1432609100 · Cited by 1,052 · see citing works

Beyond Neurons: Evidence That Immune and Glial Cells Contribute to Pathological Pain States

Watkins, L. R., & Maier, S. F. (2002) · Physiological Reviews · doi:10.1152/physrev.00011.2002 · Cited by 733 · see citing works

A systematic literature review of 10 years of research on sex/gender and experimental pain perception – Part 1: Are there really differences between women and men?

Racine, M., Tousignant-Laflamme, Y., Kloda, L. A., Dion, D., Dupuis, G., & Choinière, M. (2012) · Pain · doi:10.1016/j.pain.2011.11.025 · Cited by 691 · see citing works

GLIA: A novel drug discovery target for clinical pain

Watkins, L. R., & Maier, S. F. (2003) · Nature Reviews Drug Discovery · doi:10.1038/nrd1251 · Cited by 674 · see citing works

Understanding the broad influence of sex hormones and sex differences in the brain

McEwen, B. S., & Milner, T. A. (2017) · Journal of Neuroscience Research · doi:10.1002/jnr.23809 · Cited by 642 · see citing works

Spinal Cord Toll-Like Receptor 4 Mediates Inflammatory and Neuropathic Hypersensitivity in Male But Not Female Mice

Sorge, R. E., LaCroix‐Fralish, M. L., Tuttle, A. H., Sotocinal, S. G., Austin, J., Ritchie, J., Chanda, M. L., Graham, A. C., Topham, L., Beggs, S., et al. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.3859-11.2011 · Cited by 474 · see citing works

Males still dominate animal studies

Zucker, I., & Beery, A. K. (2010) · Nature · doi:10.1038/465690a · Cited by 460 · see citing works

Genetic control of the CD4/CD8 T-cell ratio in humans

Amadori, A., Zamarchi, R., Silvestro, G. D., Forza, G., Cavatton, G., Danieli, G. A., Clementi, M., & Chieco‐Bianchi, L. (1995) · Nature Medicine · doi:10.1038/nm1295-1279 · Cited by 440 · see citing works

Gender role expectations of pain: relationship to sex differences in pain

Robinson, M. E., Riley, J. L., Myers, C. D., Papas, R. K., Wise, E. A., Waxenberg, L. B., & Fillingim, R. B. (2001) · The Journal of Pain · doi:10.1054/jpai.2001.24551 · Cited by 423 · see citing works

Sex Differences in Pain

Sorge, R. E., & Totsch, S. K. (2016) · Journal of Neuroscience Research · doi:10.1002/jnr.23841 · Cited by 400 · see citing works

Non‐stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll‐like receptor 4 (TLR4)

Hutchinson, M. R., Zhang, Y., Brown, K., Coats, B. D., Shridhar, M., Sholar, P. W., Patel, S. J., Crysdale, N. Y., Harrison, J. A., Maier, S. F., et al. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06321.x · Cited by 399 · see citing works

T cell infiltration of the prostate induced by androgen withdrawal in patients with prostate cancer

Mercader, M., Bodner, B. K., Moser, M. T., Kwon, P. S., Park, E. S. Y., Manecke, R. G., Ellis, T. M., Wojcik, E. M., Yang, D., Flanigan, R. C., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.251140998 · Cited by 393 · see citing works

The case for the inclusion of female subjects in basic science studies of pain

Mogil, J. S., & Chanda, M. L. (2005) · Pain · doi:10.1016/j.pain.2005.06.020 · Cited by 376 · see citing works

Gender role expectations of pain: relationship to experimental pain perception

Wise, E. A., Price, D. D., Myers, C. D., Heft, M. W., & Robinson, M. E. (2002) · Pain · doi:10.1016/s0304-3959(01)00473-0 · Cited by 359 · see citing works

Gender effect on in vitro lymphocyte subset levels of healthy individuals

Abdullah, M., Chai, P., Chong, M., Tohit, E. R. M., Ramasamy, R., Chong, P. P., & Vidyadaran, S. (2011) · Cellular Immunology · doi:10.1016/j.cellimm.2011.10.009 · Cited by 343 · see citing works

Evidence for the involvement of spinal cord glia in subcutaneous formalin induced hyperalgesia in the rat

Watkins, R. L., Martin, D., Ulrich, P. C., Tracey, K. J., & Maier, F. (1997) · Pain · doi:10.1016/s0304-3959(97)03369-1 · Cited by 341 · see citing works

Androgens alter T-cell immunity by inhibiting T-helper 1 differentiation

Kissick, H. T., Sanda, M. G., Dunn, L. K., Pellegrini, K. L., On, S. T., Noel, J. K., & Arredouani, M. S. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1402468111 · Cited by 337 · see citing works

Gender as risk factor for autoimmune diseases

Gleicher, N., & Barad, D. H. (2007) · Journal of Autoimmunity · doi:10.1016/j.jaut.2006.12.004 · Cited by 337 · see citing works

Sex differences in neuroimmunity and pain

Rosen, S., Ham, B., & Mogil, J. S. (2017) · Journal of Neuroscience Research · doi:10.1002/jnr.23831 · Cited by 318 · see citing works

Spinal inhibition of p38 MAP kinase reduces inflammatory and neuropathic pain in male but not female mice: Sex-dependent microglial signaling in the spinal cord

Taves, S., Berta, T., Liu, D.-L., Gan, S., Chen, G., Kim, Y. H., de Ven, T. V., Laufer, S., & Ji, R. (2015) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2015.10.006 · Cited by 317 · see citing works

The Unexplained Female Predominance of Systemic Lupus Erythematosus: Clues from Genetic and Cytokine Studies

Weckerle, C. E., & Niewold, T. (2011) · Clinical reviews in allergy and immunology · doi:10.1007/s12016-009-8192-4 · Cited by 286 · see citing works

Sex and gender differences in pain and analgesia

Mogil, J. S., & Bailey, A. L. (2010) · Progress in brain research · doi:10.1016/b978-0-444-53630-3.00009-9 · Cited by 269 · see citing works

Sex differences in the antagonism of swim stress-induced analgesia: effects of gonadectomy and estrogen replacement

Mogil, J. S., Sternberg, W. F., Kest, B., Marek, P., & Liebeskind, J. C. (1993) · Pain · doi:10.1016/0304-3959(93)90050-y · Cited by 260 · see citing works

Regulation of the immune response by sex hormones. I. In vitro effects of estradiol and testosterone on pokeweed mitogen-induced human B cell differentiation.

Sthoeger, Z. M., Chiorazzi, N., & Lahita, R. G. (1988) · The Journal of Immunology · doi:10.4049/jimmunol.141.1.91 · Cited by 248 · see citing works

Sex differences in autoimmune diseases

Voskuhl, R. R. (2011) · Biology of Sex Differences · doi:10.1186/2042-6410-2-1 · Cited by 246 · see citing works

Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women

Griesbeck, M., Ziegler, S. M., Laffont, S., Smith, N., Chauveau, L., Tomezsko, P. J., Sharei, A., Kourjian, G., Porichis, F., Hart, M. G., et al. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1501684 · Cited by 246 · see citing works

Men, women…who cares? A population-based study on sex differences and gender roles in empathy and moral cognition

Báez, S., Flichtentrei, D., Prats, M., Mastandueno, R., García, A. M., Cetkovich, M., & Ibáñez, A. M. (2017) · PLoS ONE · doi:10.1371/journal.pone.0179336 · Cited by 246 · see citing works

Sex differences in pain

Mapplebeck, J. C. S., Beggs, S., & Salter, M. W. (2015) · Pain · doi:10.1097/j.pain.0000000000000389 · Cited by 243 · see citing works

Sex in the brain: hormones and sex differences

Marrocco, J., & McEwen, B. S. (2016) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2016.18.4/jmarrocco · Cited by 235 · see citing works

Delayed Activation of Spinal Microglia Contributes to the Maintenance of Bone Cancer Pain in Female Wistar Rats via P2X7 Receptor and IL-18

Yang, Y., Li, H., Li, T., Luo, H., Gu, X., Lü, N., Ji, R., & Zhang, Y. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.5250-14.2015 · Cited by 206 · see citing works

Sex steroid regulation of autoimmunity

Grossman, C. J., Roselle, G. A., & Mendenhall, C. L. (1991) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(91)90287-f · Cited by 203 · see citing works

Sex-Dependent Glial Signaling in Pathological Pain: Distinct Roles of Spinal Microglia and Astrocytes

Chen, G., Luo, X., Qadri, M., Berta, T., & Ji, R. (2017) · Neuroscience Bulletin · doi:10.1007/s12264-017-0145-y · Cited by 202 · see citing works

Considering Sex as a Biological Variable Will Be Valuable for Neuroscience Research

Shansky, R. M., & Woolley, C. S. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.1390-16.2016 · Cited by 191 · see citing works

Chronic pain and sex-differences; women accept and move, while men feel blue

Rovner, G. S., Sunnerhagen, K. S., Björkdahl, A., Gerdle, B., Börsbo, B., Johansson, F., & Gillanders, D. (2017) · PLOS ONE · doi:10.1371/journal.pone.0175737 · Cited by 179 · see citing works

Sex differences in microglia activity within the periaqueductal gray of the rat: A potential mechanism driving the dimorphic effects of morphine

Doyle, H. H., Eidson, L. N., Sinkiewicz, D. M., & Murphy, A. Z. (2017) · The Journal of Neuroscience · doi:10.1523/jneurosci.2906-16.2017 · Cited by 166 · see citing works

ATP receptors gate microglia signaling in neuropathic pain

Trang, T., Beggs, S., & Salter, M. W. (2011) · Experimental Neurology · doi:10.1016/j.expneurol.2011.11.012 · Cited by 161 · see citing works

Sex differences matter in the gut: effect on mucosal immune activation and inflammation

Sankaran‐Walters, S., Macal, M., Grishina, I., Nagy, L. H., Goulart, L., Coolidge, K., Li, J., Fenton, A. N., Williams, T., Miller, M. K., et al. (2013) · Biology of Sex Differences · doi:10.1186/2042-6410-4-10 · Cited by 160 · see citing works

Higher pain perception and lack of recovery from neuropathic pain in females: A behavioural, immunohistochemical, and proteomic investigation on sex-related differences in mice

Vacca, V., Marinelli, S., Pieroni, L., Urbani, A., Luvisetto, S., & Pavone, F. (2013) · Pain · doi:10.1016/j.pain.2013.10.027 · Cited by 126 · see citing works

Orofacial pain symptom prevalence: selective sex differences in the elderly?

Riley, J. L., Gilbert, G. H., & Heft, M. W. (1998) · Pain · doi:10.1016/s0304-3959(98)00030-x · Cited by 126 · see citing works

Estrogen and Inflammation Increase the Excitability of Rat Temporomandibular Joint Afferent Neurons

Flake, N., Bonebreak, D. B., & Gold, M. S. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00269.2004 · Cited by 125 · see citing works

Sex differences in peripheral not central immune responses to pain-inducing injury

Lopes, D. M., Małek, N., Edye, M. E., Jager, S. E., McMurray, S., McMahon, S. B., & Denk, F. (2017) · Scientific Reports · doi:10.1038/s41598-017-16664-z · Cited by 117 · see citing works

Microglial Regulation of Neuropathic Pain

Tsuda, M., Masuda, T., Tozaki‐Saitoh, H., & Inoue, K. (2013) · Journal of Pharmacological Sciences · doi:10.1254/jphs.12r14cp · Cited by 114 · see citing works

(+)-Naloxone, an Opioid-Inactive Toll-Like Receptor 4 Signaling Inhibitor, Reverses Multiple Models of Chronic Neuropathic Pain in Rats

Lewis, S. S., Loram, L. C., Hutchinson, M. R., Li, C., Zhang, Y., Maier, S. F., Huang, Y., Rice, K. C., & Watkins, L. R. (2012) · Journal of Pain · doi:10.1016/j.jpain.2012.02.005 · Cited by 109 · see citing works

Estrogen receptor signaling promotes dendritic cell differentiation by increasing expression of the transcription factor IRF4

Carreras, E., Turner, S., Frank, M. B., Knowlton, N. S., Osban, J., Centola, M. B., Park, C. G., Simmons, A., Alberola‐Ila, J., & Kovats, S. (2009) · Blood · doi:10.1182/blood-2009-08-236935 · Cited by 103 · see citing works

Pain-Related Rumination, But Not Magnification or Helplessness, Mediates Race and Sex Differences in Experimental Pain

Meints, S. M., Stout, M. E., Abplanalp, S. J., & Hirsh, A. T. (2016) · Journal of Pain · doi:10.1016/j.jpain.2016.11.005 · Cited by 93 · see citing works

Sex and Genotype Determine the Selective Activation of Neurochemically-Distinct Mechanisms of Swim Stress-Induced Analgesia

Mogil, J. S., & Belknap, J. K. (1997) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(96)00157-8 · Cited by 90 · see citing works

Molecules in pain and sex: a developing story

Mapplebeck, J. C. S., Beggs, S., & Salter, M. W. (2017) · Molecular Brain · doi:10.1186/s13041-017-0289-8 · Cited by 90 · see citing works

Neuron–microglia interaction by purinergic signaling in neuropathic pain following neurodegeneration

Tsuda, M., & Inoue, K. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.08.042 · Cited by 86 · see citing works

Sex differences in N-methyl-d-aspartate involvement in κ opioid and non-opioid predator-induced analgesia in mice

Kavaliers, M., & Choleris, E. (1997) · Brain Research · doi:10.1016/s0006-8993(97)00569-6 · Cited by 78 · see citing works

Sex differences in mechanical allodynia: how can it be preclinically quantified and analyzed?

Nicotra, L. L., Tuke, J., Grace, P. M., Rolan, P. E., & Hutchinson, M. R. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00040 · Cited by 77 · see citing works

Pain Catastrophizing Moderates Relationships between Pain Intensity and Opioid Prescription

Sharifzadeh, Y., Kao, M. J., Sturgeon, J. A., Rico, T. J., Mackey, S., & Darnall, B. D. (2017) · Anesthesiology · doi:10.1097/aln.0000000000001656 · Cited by 76 · see citing works

Gender Issues in Multiple Sclerosis

Schwendimann, R. N., & Alekseeva, N. (2007) · International review of neurobiology · doi:10.1016/s0074-7742(07)79017-7 · Cited by 74 · see citing works

Development of the Sensory Hypersensitivity Scale (SHS): a self-report tool for assessing sensitivity to sensory stimuli

Dixon, E. A., Benham, G., Sturgeon, J. A., Mackey, S., Johnson, K. A., & Younger, J. (2016) · Journal of Behavioral Medicine · doi:10.1007/s10865-016-9720-3 · Cited by 70 · see citing works

Sex in Context: Limitations of Animal Studies for Addressing Human Sex/Gender Neurobehavioral Health Disparities

Eliot, L., & Richardson, S. S. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.1391-16.2016 · Cited by 70 · see citing works

Sex differences in the relationships between parasympathetic activity and pain modulation

Nahman‐Averbuch, H., Dayan, L., Sprecher, E., Hochberg, U., Brill, S., Yarnitsky, D., & Jacob, G. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2015.11.004 · Cited by 66 · see citing works

Inflammation-induced pain sensitization in men and women

Wegner, A., Elsenbruch, S., Rebernik, L., Roderigo, T., Engelbrecht, E., Jäger, M., Engler, H., Schedlowski, M., & Benson, S. (2015) · Pain · doi:10.1097/j.pain.0000000000000256 · Cited by 66 · see citing works

Sex differences in a Murine Model of Complex Regional Pain Syndrome

Tajerian, M., Sahbaie, P., Sun, Y., Leu, D., Yang, H. Y., Li, W., Huang, T., Kingery, W. S., & Clark, J. D. (2015) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2015.06.004 · Cited by 63 · see citing works

Sex differences in the expression and antagonism of swim stress-induced analgesia in deer mice vary with the breeding season

Kavaliers, M., & Galea, L. A. M. (1995) · Pain · doi:10.1016/0304-3959(95)00063-1 · Cited by 61 · see citing works

Sex Differences in Innate Immunity and Its Impact on Opioid Pharmacology

Doyle, H. H., & Murphy, A. Z. (2017) · Journal of Neuroscience Research · doi:10.1002/jnr.23852 · Cited by 59 · see citing works

Sex differences in primary muscle afferent sensitization following ischemia and reperfusion injury

Ross, J. L., Queme, L. F., Lamb, J. E., Green, K. J., & Jankowski, M. P. (2018) · Biology of Sex Differences · doi:10.1186/s13293-017-0163-5 · Cited by 55 · see citing works

Gender differences in the experience of pain dismissal in adolescence

Igler, E. C., Defenderfer, E. K., Lang, A. C., Bauer, K., Uihlein, J., & Davies, W. H. (2017) · Journal of Child Health Care · doi:10.1177/1367493517727132 · Cited by 54 · see citing works

Sex Differences in the Neural Representation of Pain Unpleasantness

Girard-Tremblay, L., Auclair, V., Daigle, K., Léonard, G., Whittingstall, K., & Goffaux, P. (2014) · Journal of Pain · doi:10.1016/j.jpain.2014.05.004 · Cited by 53 · see citing works

Sex differences and estradiol involvement in hyperalgesia and allodynia in an experimental model of fibromyalgia

Hernández-León, A., la Luz-Cuellar, Y. E. D., Granados‐Soto, V., González-Trujano, M. E., & Fernández‐Guasti, A. (2017) · Hormones and Behavior · doi:10.1016/j.yhbeh.2017.10.011 · Cited by 52 · see citing works

Differential Effect of Patient Weight on Pain-Related Judgements About Male and Female Chronic Low Back Pain Patients

Miller, M. M., Allison, A., Trost, Z., Ruddere, L. D., Wheelis, T., Goubert, L., & Hirsh, A. T. (2017) · Journal of Pain · doi:10.1016/j.jpain.2017.09.001 · Cited by 50 · see citing works

Sex Differences in Peripheral Mu-Opioid Receptor Mediated Analgesia in Rat Orofacial Persistent Pain Model

Bai, X., Zhang, X., Li, Y., Lu, L., Лі, Б., & He, X. (2015) · PLoS ONE · doi:10.1371/journal.pone.0122924 · Cited by 49 · see citing works

Sex Differences in Brain Regions Modulating Pain Among Older Adults: A Cross-Sectional Resting State Functional Connectivity Study

Monroe, T. B., Fillingim, R. B., Bruehl, S. P., Rogers, B. P., Dietrich, M. S., Gore, J. C., Atalla, S., & Cowan, R. L. (2017) · Pain Medicine · doi:10.1093/pm/pnx084 · Cited by 42 · see citing works

Consistent sex-dependent effects of PKMζ gene ablation and pharmacological inhibition on the maintenance of referred pain

Nasir, H., Mahboubi, H., Gyawali, S., Ding, S., Mickeviciute, A., Ragavendran, J. V., Laferrière, A., Stochaj, U., & Coderre, T. J. (2016) · Molecular Pain · doi:10.1177/1744806916675347 · Cited by 39 · see citing works

Sex differences in monocytes and TLR4 associated immune responses; implications for systemic lupus erythematosus (SLE)

Jiang, W., & Gilkeson, G. S. (2014) · Journal of Immunotherapy Applications · doi:10.7243/2055-2394-1-1 · Cited by 37 · see citing works

Females report higher postoperative pain scores than males after ankle surgery

Storesund, A., Krukhaug, Y., Olsen, M. V., Rygh, L. J., Nilsen, R. M., & Norekvål, T. M. (2016) · Scandinavian Journal of Pain · doi:10.1016/j.sjpain.2016.05.001 · Cited by 34 · see citing works

Gender Difference in Cancer Patients’ Adherence to Analgesics and Related Outcomes of Pain Management

Chou, P., Fang, S., Sun, J., Rau, K.-M., & Lee, B. (2017) · Cancer Nursing · doi:10.1097/ncc.0000000000000532 · Cited by 34 · see citing works

Sex differences in opioid and N -methyl-d-aspartate mediated non-opioid biting fly exposure induced analgesia in deer mice

Kavaliers, M., Colwell, D. D., & Choleris, E. (1998) · Pain · doi:10.1016/s0304-3959(98)00092-x · Cited by 33 · see citing works

Inflammatory Pain Reduces C Fiber Activity-Dependent Slowing in a Sex-Dependent Manner, Amplifying Nociceptive Input to the Spinal Cord

Dickie, A. C., McCormick, B., Lukito, V., Wilson, K. L., & Torsney, C. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.3816-16.2017 · Cited by 33 · see citing works

Sex differences in the inflammatory mediator-induced sensitization of dural afferents

Scheff, N. N., & Gold, M. S. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00196.2011 · Cited by 27 · see citing works

Neonatal Injury Results in Sex-Dependent Nociceptive Hypersensitivity and Social Behavioral Deficits During Adolescence, Without Altering Morphine Response

Burke, N. N., & Trang, T. (2017) · Journal of Pain · doi:10.1016/j.jpain.2017.07.003 · Cited by 24 · see citing works

Sex moderates the effects of positive and negative affect on clinical pain in patients with knee osteoarthritis

Speed, T. J., Richards, J., Finan, P. H., & Smith, M. T. (2017) · Scandinavian Journal of Pain · doi:10.1016/j.sjpain.2017.03.005 · Cited by 23 · see citing works

Pain anxiety and fear of (re) injury in patients with chronic back pain: Sex as a moderator

Kreddig, N., & Hasenbring, M. I. (2017) · Scandinavian Journal of Pain · doi:10.1016/j.sjpain.2017.03.009 · Cited by 21 · see citing works

Mild Depression in Low Back Pain: the Interaction of Thought Suppression and Stress Plays a Role, Especially in Female Patients

Konietzny, K., Chehadi, O., Streitlein-Böhme, I., Rusche, H., Willburger, R., & Hasenbring, M. I. (2017) · International Journal of Behavioral Medicine · doi:10.1007/s12529-017-9657-0 · Cited by 19 · see citing works

Effects of Sex and Stress on Trigeminal Neuropathic Pain-Like Behavior in Rats

Korczeniewska, O. A., Khan, J., Tao, Y., Eliav, E., & Benoliel, R. (2017) · Journal of Oral & Facial Pain and Headache · doi:10.11607/ofph.1807 · Cited by 19 · see citing works

Estradiol downregulates NF-κb translocation by Ikbkg transcriptional repression in dendritic cells

Lasarte, S., Elsner, D., Sánchez-Elsner, T., Fernández-Pineda, A., López-Fernández, L. A., Corbí, A. L., Muñoz‐Fernández, M. Á., & Relloso, M. (2013) · Genes and Immunity · doi:10.1038/gene.2013.35 · Cited by 17 · see citing works

Biopsychosocial contributions to sex differences in pain

Fillingim, R. B. (2015) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.13337 · Cited by 16 · see citing works

Gender differences in pain and patient reported outcomes: a secondary analysis of the NCIC CTG SC. 23 randomized trial

Chow, S. L.-M., Ding, K., Wan, B. A., Brundage, M., Meyer, R. M., Nabid, A., Chabot, P., Coulombe, G., Ahmed, S., Kuk, J., et al. (2017) · Annals of Palliative Medicine · doi:10.21037/apm.2017.08.12 · Cited by 16 · see citing works

Sex differences in the decoding of pain‐related body postures

Walsh, J., Eccleston, C., & Keogh, E. (2017) · European Journal of Pain · doi:10.1002/ejp.1072 · Cited by 12 · see citing works

Qualitative sex differences in pain processing: emerging evidence of a biased literature

Mogil, J. S. (2020) · Nature Reviews Neuroscience · doi:10.1038/s41583-020-0310-6 · Cited by 691 · see citing works

Delivering transformative action in paediatric pain: a Lancet Child & Adolescent Health Commission

Eccleston, C., Fisher, E., Howard, R. F., Slater, R., Forgeron, P. A., Palermo, T. M., Birnie, K. A., Anderson, B. J., Chambers, C. T., Crombez, G., et al. (2020) · The Lancet Child & Adolescent Health · doi:10.1016/s2352-4642(20)30277-7 · Cited by 338 · see citing works

Painful and Painless Diabetic Neuropathies: What Is the Difference?

SHILLO, P. R., SLOAN, G. P., Greig, M., Hunt, L., Selvarajah, D., Elliott, D., Gandhi, R. A., Wilkinson, I. D., & Tesfaye, S. H. (2019) · Current Diabetes Reports · doi:10.1007/s11892-019-1150-5 · Cited by 185 · see citing works

A Systematic Review of Race, Sex, and Socioeconomic Status Differences in Postoperative Pain and Pain Management

Thurston, K. L., Zhang, S. J., Wilbanks, B. A., Billings, R., & Aroke, E. N. (2022) · Journal of PeriAnesthesia Nursing · doi:10.1016/j.jopan.2022.09.004 · Cited by 110 · see citing works

A Brief Overview: Sex Differences in Prevalent Chronic Musculoskeletal Conditions

Overstreet, D., Strath, L. J., Jordan, M., Jordan, I. A., Hobson, J., Owens, M., Williams, A. C., Edwards, R., & Meints, S. M. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20054521 · Cited by 104 · see citing works

Could epigenetics help explain racial disparities in chronic pain?

Aroke, E. N., Joseph, P. V., Roy, A., Overstreet, D. S., Tollefsbol, T. O., Vance, D. E., & Goodin, B. R. (2019) · Journal of Pain Research · doi:10.2147/jpr.s191848 · Cited by 84 · see citing works

Featured Article: Gender Bias in Pediatric Pain Assessment

Earp, B. D., Monrad, J. T., LaFrance, M., Bargh, J. A., Cohen, L. L., & Richeson, J. A. (2018) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/jsy104 · Cited by 74 · see citing works

Sources of Individual Differences in Pain

Mogil, J. S. (2021) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-092820-105941 · Cited by 73 · see citing works

Why and How to Account for Sex and Gender in Brain and Behavioral Research

Eliot, L., Beery, A. K., Jacobs, E. G., LeBlanc, H. F., Maney, D. L., & McCarthy, M. M. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.0020-23.2023 · Cited by 61 · see citing works

Neuroimmune interactions in chronic pain – An interdisciplinary perspective

Hore, Z. L., & Denk, F. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.04.033 · Cited by 54 · see citing works

Kinesiophobia Is Associated With Pain Intensity and Disability in Chronic Shoulder Pain: A Cross-Sectional Study

Luque-Suárez, A., Martínez-Calderón, J., Ledesma, S. N., Morales‐Asencio, J. M., Meeus, M., & Struyf, F. (2020) · Journal of Manipulative and Physiological Therapeutics · doi:10.1016/j.jmpt.2019.12.009 · Cited by 55 · see citing works

Does Pain at an Earlier Stage of Chondropathy Protect Female Mice Against Structural Progression After Surgically Induced Osteoarthritis?

von Loga, I. S., Batchelor, V., Driscoll, C., Burleigh, A., Chia, S., Stott, B., Miotla‐Zarebska, J., Riley, D., Dell’Accio, F., & Vincent, T. L. (2020) · Arthritis & Rheumatology · doi:10.1002/art.41421 · Cited by 44 · see citing works

Sexually dimorphic therapeutic response in bortezomib-induced neuropathic pain reveals altered pain physiology in female rodents

Stockstill, K., Wahlman, C., Braden, K., Chen, Z., Yosten, G. L. C., Tosh, D. K., Jacobson, K. A., Doyle, T. M., Samson, W. K., & Salvemini, D. (2019) · Pain · doi:10.1097/j.pain.0000000000001697 · Cited by 42 · see citing works

Reprogramming the topology of the nociceptive circuit in C. elegans reshapes sexual behavior

Pechuk, V., Goldman, G., Salzberg, Y., Chaubey, A. H., Bola, R. A., Hoffman, J. R., Endreson, M. L., Miller, R. M., Reger, N. J., Portman, D., et al. (2022) · Current Biology · doi:10.1016/j.cub.2022.08.038 · Cited by 42 · see citing works

Microglial heterogeneity in chronic pain

Sideris-Lampretsas, G., & Malcangio, M. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.06.005 · Cited by 37 · see citing works

Sickle-Cell Disease Co-Management, Health Care Utilization, and Hydroxyurea Use

Crego, N., Douglas, C. E., Bonnabeau, E., Earls, M. F., Eason, K., Merwin, E., Rains, G., Tanabe, P. J., & Shah, N. (2020) · The Journal of the American Board of Family Medicine · doi:10.3122/jabfm.2020.01.190143 · Cited by 37 · see citing works

Sexually dimorphic architecture and function of a mechanosensory circuit in C. elegans

Setty, H., Salzberg, Y., Karimi, S., Berent-Barzel, E., Krieg, M., & Oren‐Suissa, M. (2022) · Nature Communications · doi:10.1038/s41467-022-34661-3 · Cited by 36 · see citing works

Early life pain—effects in the adult

Walker, S. M. (2019) · Current Opinion in Physiology · doi:10.1016/j.cophys.2019.04.011 · Cited by 36 · see citing works

Sex-Related Differential Whole-Brain Input Atlas of Locus Coeruleus Noradrenaline Neurons

Sun, P., Wang, J., Zhang, M., Duan, X., Wei, Y., Xu, F., Ma, Y., & Zhang, Y.-H. (2020) · Frontiers in Neural Circuits · doi:10.3389/fncir.2020.00053 · Cited by 37 · see citing works

Codeine and Tramadol Use in Athletes: A Potential for Abuse

Zandonai, T., Escorial, M., & Peiró, A. M. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.661781 · Cited by 30 · see citing works

Psychological factors are associated with local and generalized pressure pain hypersensitivity, pain intensity, and function in people with chronic shoulder pain: A cross-sectional study

Martínez-Calderón, J., Meeus, M., Struyf, F., Díaz-Cerrillo, J. L., Clavero-Cano, S., Morales‐Asencio, J. M., & Luque-Suárez, A. (2019) · Musculoskeletal Science and Practice · doi:10.1016/j.msksp.2019.102064 · Cited by 30 · see citing works

Sex differences in central nervous system plasticity and pain in experimental autoimmune encephalomyelitis

Catuneanu, A., Paylor, J. W., Winship, I. R., Colbourne, F., & Kerr, B. J. (2019) · Pain · doi:10.1097/j.pain.0000000000001483 · Cited by 29 · see citing works

Behavioral and inflammatory sex differences revealed by celecoxib nanotherapeutic treatment of peripheral neuroinflammation

Deal, B., Reynolds, L. M., Patterson, C., Janjic, J. M., & Pollock, J. A. (2022) · Scientific Reports · doi:10.1038/s41598-022-12248-8 · Cited by 25 · see citing works

Effects of Coping Flexibility in Young Women on Depressive Symptoms during Chronic Pain

Kato, T., Kadota, M., & Shimoda, S. (2019) · Behavioral Medicine · doi:10.1080/08964289.2019.1708250 · Cited by 24 · see citing works

Early-life programming of pain sensation? Spinal pain in pre-adolescents with pain experience in early life

Falch-Joergensen, A. C., Lucas, R., Hestbæk, L., Andersen, P. K., & Andersen, A. N. (2019) · European Journal of Pediatrics · doi:10.1007/s00431-019-03475-9 · Cited by 23 · see citing works

The Operant Plantar Thermal Assay: A Novel Device for Assessing Thermal Pain Tolerance in Mice

Reker, A. N., Chen, S., Etter, K., Burger, T., Caudill, M., & Davidson, S. (2020) · eNeuro · doi:10.1523/eneuro.0210-19.2020 · Cited by 23 · see citing works

Sex differences in the role of atypical PKC within the basolateral nucleus of the amygdala in a mouse hyperalgesic priming model

Baptista‐de‐Souza, D., Tavares‐Ferreira, D., Megat, S., Sankaranarayanan, I., Shiers, S. I., Flores, C. M., Ghosh, S., Nunes‐de‐Souza, R. L., Canto‐de‐Souza, A., & Price, T. J. (2020) · Neurobiology of Pain · doi:10.1016/j.ynpai.2020.100049 · Cited by 22 · see citing works

Dietary Inflammatory Index (DII) is Associated with Movement-Evoked Pain Severity in Adults with Chronic Low Back Pain: Sociodemographic Differences.

Strath, L. J., Sims, A., Overstreet, D. S., Penn, T. M., Bakshi, R. J., Stansel, B. K., Quinn, T. L., Sorge, R. E., Long, D. L., & Goodin, B. R. (2022) · Journal of Pain · doi:10.1016/j.jpain.2022.03.237 · Cited by 22 · see citing works

Racial Differences in Pain, Nutrition, and Oxidative Stress

Strath, L. J., & Sorge, R. E. (2022) · Pain and Therapy · doi:10.1007/s40122-022-00359-z · Cited by 21 · see citing works

Effect of Psychological Inflexibility on Depressive Symptoms and Sleep Disturbance among Japanese Young Women with Chronic Pain

Kato, T. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17207426 · Cited by 22 · see citing works

Changes in the expression of endocannabinoid system components in an experimental model of chemotherapy-induced peripheral neuropathic pain: Evaluation of sex-related differences

Noya-Riobó, M. V., Miguel, C. Á., Soriano, D., Brumovsky, P. R., Villar, M. J., & Coronel, M. F. (2022) · Experimental Neurology · doi:10.1016/j.expneurol.2022.114232 · Cited by 20 · see citing works

Effects of Mindfulness-Based Stress Reduction on Experimental Pain Sensitivity and Cortisol Responses in Women with Early Life Abuse: A Randomized Controlled Trial

Andersen, E., Geiger, P., Schiller, C., Bluth, K., Watkins, L., Zhang, Y., Xia, K., Tauseef, H., Leserman, J., Girdler, S., et al. (2021) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000889 · Cited by 19 · see citing works

Relationship Between Diet and Relative Risk of Pain in a Cross-Sectional Analysis of the REGARDS Longitudinal Study

Strath, L. J., Brooks, M. S., Sorge, R. E., & Judd, S. E. (2021) · Pain Management · doi:10.2217/pmt-2021-0048 · Cited by 19 · see citing works

Socioeconomic Status, Knee Pain, and Epigenetic Aging in Community-Dwelling Middle-to-Older Age Adults

Strath, L. J., Peterson, J. A., Meng, L., Rani, A., Huo, Z., Foster, T. C., Fillingim, R. B., & Cruz‐Almeida, Y. (2023) · Journal of Pain · doi:10.1016/j.jpain.2023.06.002 · Cited by 16 · see citing works

An acquired or heritable connective tissue disorder? A review of hypermobile Ehlers Danlos Syndrome

Martin, A. (2019) · European Journal of Medical Genetics · doi:10.1016/j.ejmg.2019.103672 · Cited by 16 · see citing works

Paclitaxel-Associated Mechanical Sensitivity and Neuroinflammation Are Sex-, Time-, and Site-Specific and Prevented through Cannabigerol Administration in C57Bl/6 Mice

Li, H., & Ward, S. J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25084277 · Cited by 15 · see citing works

Experience of Pain and Satisfaction with Pain Management in Patients After a Lumbar Disc Herniation Surgery

Sınmaz, T., & Akansel, N. (2021) · Journal of PeriAnesthesia Nursing · doi:10.1016/j.jopan.2021.01.009 · Cited by 15 · see citing works

Sex-related differences in oxaliplatin-induced changes in the expression of transient receptor potential channels and their contribution to cold hypersensitivity

Miguel, C. Á., Noya-Riobó, M. V., Brumovsky, P. R., Villar, M. J., & Coronel, M. F. (2022) · Neuroscience Letters · doi:10.1016/j.neulet.2022.136863 · Cited by 13 · see citing works

Understanding sex differences in zebrafish pain- and fear-related behaviors

Marcon, L., Giacomini, A. C. V. V., dos Santos, B. E., Costa, F. V., Rosemberg, D. B., Demin, K. A., Kalueff, A. V., & de Abreu, M. S. (2021) · Neuroscience Letters · doi:10.1016/j.neulet.2021.136412 · Cited by 12 · see citing works

Postoperative pain facilitates rat C-fibre activity-dependent slowing and induces thermal hypersensitivity in a sex-dependent manner

Velichkova, A. N., Coleman, S. E., & Torsney, C. (2022) · British Journal of Anaesthesia · doi:10.1016/j.bja.2021.10.053 · Cited by 12 · see citing works

Gender Bias in Pediatric Pain AssessmentPreprint

Earp, B. D., Monrad, J. T., LaFrance, M., Bargh, J. A., Cohen, L. L., & Richeson, J. A. (2018) · doi:10.31234/osf.io/pqg3a · Cited by 12 · see citing works

Beneficial Effects of Ginger Root Extract on Pain Behaviors, Inflammation, and Mitochondrial Function in the Colon and Different Brain Regions of Male and Female Neuropathic Rats: A Gut–Brain Axis Study

Santos, J. M., Deshmukh, H., Elmassry, M. M., Yakhnitsa, V., Ji, G., Kiritoshi, T., Presto, P., Antenucci, N., Liu, X., Neugebauer, V., et al. (2024) · Nutrients · doi:10.3390/nu16203563 · Cited by 11 · see citing works

A Study on Peripheral Neuropathy and Its Related Risk Factors Associated With hba1c Levels

Hossain, M., Sarkar, M., Mahbub, I., & Islam, S. (2021) · Journal of Bio-Science · doi:10.3329/jbs.v29i2.54961 · Cited by 11 · see citing works

Divergent association between pain intensity and resting‐state fMRI ‐based brain entropy in different age groups

Mauro, G. D., Sevel, L. S., Boissoneault, J., & Wang, Z. (2024) · Journal of Neuroscience Research · doi:10.1002/jnr.25341 · Cited by 9 · see citing works

Adversity type and timing predict temporal summation of pain in African-American adults

Morris, M. C., Goodin, B. R., Bruehl, S. P., Myers, H. F., Rao, U., Karlson, C., Huber, F. A., Nag, S., Carter, C., Kinney, K. L., et al. (2023) · Journal of Behavioral Medicine · doi:10.1007/s10865-023-00440-8 · Cited by 8 · see citing works

Clinical vitamin D levels are associated with insular volume and inferior temporal gyrus white matter surface area in community-dwelling individuals with knee pain

Strath, L. J., Valdes-Hernandez, P. A., Nodarse, C. L., Johnson, A. J., Edberg, J. D., Fillingim, R. B., & Cruz‐Almeida, Y. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.882322 · Cited by 8 · see citing works

Peritraumatic Pain in Child Maltreatment: A Systematic Literature Review

Tsur, N., Talmon, A., & Shemesh, N. (2023) · Trauma Violence & Abuse · doi:10.1177/15248380231194069 · Cited by 7 · see citing works

Improvement Trajectories in Patient-Reported Outcomes Between Males and Females After Anterior Cruciate Ligament Reconstruction

Bjornsen, E. S., Lisee, C. M., Schwartz, T. A., Creighton, R. A., Kamath, G. V., Spang, J. T., Blackburn, J. T., & Pietrosimone, B. (2022) · Journal of Athletic Training · doi:10.4085/1062-6050-0093.22 · Cited by 7 · see citing works

The Comparison of The Effectiveness of Local Ice and Manual Pressure Application in Decreasing Pain Related to Intramuscular Injection

Bilgiç, Ş. (2021) · Clinical and Experimental Health Sciences · doi:10.33808/clinexphealthsci.778676 · Cited by 6 · see citing works

Associations between endogenous sex hormones and multisite chronic musculoskeletal pain

Kifle, Z. D., Tian, J., Aitken, D. A., Melton, P. E., Cicuttini, F., Jones, G., & Pan, F. (2024) · British Journal of Anaesthesia · doi:10.1016/j.bja.2024.11.021 · Cited by 5 · see citing works

Sex Differences in the Expression of Neuroimmune Molecules in the Spinal Cord of a Mouse Model of Antiretroviral-Induced Neuropathic Pain

Al-HadlaQ, M. W., & Masocha, W. (2023) · Biomedicines · doi:10.3390/biomedicines11030875 · Cited by 5 · see citing works

Activational and organizational actions of gonadal hormones on the sexual dimorphism of the α6-subunit containing GABAA receptor in Wistar rats with neuropathic pain

Pizaña-Encarnación, J. M., Escoto-Rosales, M. J., Islas-Espinoza, A. M., Morales-Galindo, D. K., Déciga‐Campos, M., Quintanar, B. G., Reyes, R., Granados‐Soto, V., & Fernández‐Guasti, A. (2025) · Hormones and Behavior · doi:10.1016/j.yhbeh.2025.105746 · Cited by 4 · see citing works

The effect of Blastocystis sp. and Dientamoeba fragilis on psychological symptom severity in a sample of clinically diverse males and females

Ganci, M., Butt, H., Tyrrell, J., Suleyman, E., & Ball, M. (2021) · Current Psychology · doi:10.1007/s12144-021-01700-z · Cited by 4 · see citing works

Sex differences in pain perception and modulation in the brain: effects of insular cortex stimulation on chronic pain relief

Kwon, M., Kim, K., Eum, Y.-J., Nan, G., Kim, L., Park, H.-J., Kim, U. J., Sohn, J., Cheong, C., Cho, J., et al. (2025) · Brain Communications · doi:10.1093/braincomms/fcaf362 · Cited by 3 · see citing works

Analgesic protocol for procedural pain treatment of second-degree burns in children

Komarčević, A., Jokić, R., Pajić, M., Jovanović, M., & Milenković, M. (2022) · Vojnosanitetski pregled · doi:10.2298/vsp220305043k · Cited by 3 · see citing works

Sex Differences in Pain with Emphasis on Neuroimmune Interactions

Luo, X., Ji, J., & Ji, R. (2023) · Springer eBooks · doi:10.1007/978-3-031-29231-6_6 · Cited by 3 · see citing works

CİNSİYETTEN BEKLENEN DAVRANIŞLAR KRONİK AĞRIYA VERİLEN TEPKİLERİ ETKİLER Mİ?

NAZİK, G., & Yılmaz, M. (2022) · Karya Journal of Health Science · doi:10.52831/kjhs.1082893 · Cited by 2 · see citing works

Selection of experimental models mimicking human pathophysiology for diabetic microvascular complications

Gandhi, T., Patel, A., & Purohit, M. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-90583-1.00034-9 · Cited by 2 · see citing works

Sex difference in musculoskeletal disabilities among Korean fishers: a cross-sectional study

Kim, H.-M., Park, S. H., Ju, B., Park, K., Kim, J. H., & Song, H. S. (2025) · Annals of Occupational and Environmental Medicine · doi:10.35371/aoem.2025.37.e18 · Cited by 1 · see citing works

Examination of factors affecting pain-related self-efficacy in patients with chronic neck pain

Atçeken, H., & Duray, M. (2023) · Medical Science and Discovery · doi:10.36472/msd.v10i5.930 · Cited by 1 · see citing works

Effect of analgesic treatments on voluntary activity, mechanical sensitivity and muscle regeneration after cardiotoxin injection in mice

Jomard, C., Boyer, N., Fessard, A., Chazaud, B., & Gondin, J. (2025) · Scientific Reports · doi:10.1038/s41598-025-13118-9 · Cited by 1 · see citing works

Editorial overview: Daylighting sex differences in physiology

Goodwin, S. F., & Howlett, S. E. (2018) · Current Opinion in Physiology · doi:10.1016/j.cophys.2018.09.002 · Cited by 1 · see citing works

Effectiveness of Manual Therapy as an Adjunct to Care as Normal in Female Chronic Migraine Patients. A Randomised Controlled TrialPreprint

Odell, J., Branney, J., & Hunnisett, A. (2022) · Research Square · doi:10.21203/rs.3.rs-2291690/v1 · Cited by 1 · see citing works

Reviewer #3 (Public Review): Exposure to false cardiac feedback alters pain perception and anticipatory cardiac frequency

Parrotta, E., Bach, P., Pezzulo, G., et al. (2023) · eLife · doi:10.7554/elife.90013.1.sa0

Onkoloji Kliniğinde Yatan 18-65 Yaş Arası Hastaların Ağrıyla Baş Etme Yöntemlerinin Belirlenmesi

Ordu, Y. (2024) · Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi · doi:10.37989/gumussagbil.1367604

Differential DNA methylation profiles of Alzheimer's disease-related genomic pathways in the blood of cognitively-intact individuals with and without high impact chronic pain

Strath, L. J., Meng, L., Zhang, Y., Rani, A., Huo, Z., Foster, T. C., Fillingim, R. B., & Cruz‐Almeida, Y. (2024) · Journal of Alzheimer s Disease Reports · doi:10.1177/25424823241289376

Development of the Yale pain stress test to elicit a multi-level stress response and assess stress adaptability

Fogelman, N., Barreto, S., McGowan, C. R., Wemm, S., & Sinha, R. (2025) · Psychopharmacology · doi:10.1007/s00213-025-06972-y

A state-dependent neural circuit resolves approach–avoidance conflictsPreprint

Bodas, D. S., Demirci, S., Balcou, M., Scheunemann, L., & Rezával, C. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.02.05.704045

Cellular and Behavioral Interactions of Cannabinoid and Opioid Systems in Pain, Mood, Reward, and Addiction

Mohammadkhani, A., Peterson, C. S., & Borgland, S. L. (2026) · Springer eBooks · doi:10.1007/978-3-032-12239-1_14

Sexually dimorphic roles of toll-like receptors in the central nervous system

Elkabes, S. (2026) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2026.106830

Gender Differences in Low Backache

Nahar, S., & Agrawal, P. (2026) · Springer eBooks · doi:10.1007/978-981-97-4087-1_55-1

Preclinical characterization of the efficacy and safety of histamine H3 receptor antagonist, LINS01022, as a novel analgesic for chronic neuropathic pain treatment

Maciuszek, M., Białoń, M., Królewski, M., Noworyta, K., Fiocchi, N. A., Lopes, F. B., Starowicz, K., Gouveia, W. L., Lima, L. M., Fernandes, J. P. S., et al. (2026) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2026.179265

Understanding risk and protective factors for pain and healthy aging: an intersectional and resilience-based perspective

Hobson, J. M., Jordan, I. A., Kim, S., & Taylor, T. L. (2026) · Frontiers in Pain Research · doi:10.3389/fpain.2026.1885948

Sex differences in chronic pain conditions: An attempt to overcome the gender pain gap

Chaudhry, A. (2025) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2025.125522

Sex differences in pain do exist: The role of biological and psychosocial factors

Rollman, G. B. (1997) · Behavioral and Brain Sciences · doi:10.1017/s0140525x97491495 · Cited by 4 · see citing works

Biopsychosocial contributions to sex differences in pain

Fillingim, R. B. (2015) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.13337 · Cited by 16 · see citing works

Sex Differences in Pain

Sorge, R. E., & Totsch, S. K. (2016) · Journal of Neuroscience Research · doi:10.1002/jnr.23841 · Cited by 400 · see citing works

Sex, gender, and pain: women and men really are different

Fillingim, R. B. (2000) · Current Review of Pain · doi:10.1007/s11916-000-0006-6 · Cited by 488 · see citing works