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Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

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Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

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The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver

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Mammalian sirtuins—emerging roles in physiology, aging, and calorie restriction

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Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress

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Increased Nuclear NAD Biosynthesis and SIRT1 Activation Prevent Axonal Degeneration

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SIRT1 Functionally Interacts with the Metabolic Regulator and Transcriptional Coactivator PGC-1α

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The NAD Biosynthesis Pathway Mediated by Nicotinamide Phosphoribosyltransferase Regulates Sir2 Activity in Mammalian Cells

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Inhibition of Silencing and Accelerated Aging by Nicotinamide, a Putative Negative Regulator of Yeast Sir2 and Human SIRT1

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Nutrient-Sensitive Mitochondrial NAD+ Levels Dictate Cell Survival

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Nampt/PBEF/Visfatin Regulates Insulin Secretion in β Cells as a Systemic NAD Biosynthetic Enzyme

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An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans

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Resveratrol stimulates AMP kinase activity in neurons

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SIRT1 transgenic mice show phenotypes resembling calorie restriction

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Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells

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The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans

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Calorie restriction extends yeast life span by lowering the level of NADH

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Sirtuins in aging and age-related disease

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The Mammalian SIR2α Protein Has a Role in Embryogenesis and Gametogenesis

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SIRT1 Controls Endothelial Angiogenic Functions During Vascular Growth

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Increase in Activity During Calorie Restriction Requires Sirt1

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Molecular cloning, chromosomal localization, tissue mRNA levels, bacterial expression, and enzymatic properties of human NMN adenylyltransferase

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AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

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NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

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SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function

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From discoveries in ageing research to therapeutics for healthy ageing

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Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice

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