Cited by 262Endometriosis Research and TreatmentHealth Systems, Economic Evaluations, Quality of LifeMusculoskeletal pain and rehabilitation

The DOI matches its Crossref record; 48 of the 52 references it cites were found in a registry or an index; none of the 41 sources its claims cite is checked for support yet.

Quantification of the impact of endometriosis symptoms on health-related quality of life and work productivity

Open access

Abstract

OBJECTIVE To quantify the impact of endometriosis-related symptoms on physical and mental health status, health-related quality of life (HRQoL), and work-related aspects (absenteeism, presenteeism, work productivity, activity impairment). DESIGN Cross-sectional quantitative study. SETTING Academic and research institution. PATIENT(S) Women (n=193) with self-reported surgically diagnosed endometriosis from the Endometriosis Patient Registry at Ponce School of Medicine and Health Sciences (PSMHS). INTERVENTION(S) Patients completed an anonymous questionnaire divided into three sections consisting of questions from the Patient Health Survey (SF-12®), the Endometriosis Health Profile (EHP-5), and the Work Productivity and Activity Impairment Survey (WPAI). MAIN OUTCOME MEASURE(S) Impact of endometriosis symptoms on physical and mental health status, health-related quality of life (HRQoL), absenteeism, presenteeism, work productivity and activity impairment was quantified. RESULTS Patients had SF-12 scores denoting significant disability in the phyisical and mental health components. They also reported an average of 7.41 hrs (approximately one working day) of work time loss during the week the symptoms are worse. In addition, WPAI scores show high impact on work-related domains: 13% of average loss in work time (absenteeism), 65% of their work was impaired (presenteeism), 64% loss in efficiency levels (work productivity loss), and 60% of daily activities perturbed (activity impairment). CONCLUSION Endometriosis symptoms such as chronic, incapacitating pelvic pain and infertility negatively and substantially impact the physical and mental health status, HRQoL, and productivity at work of patients with endometriosis.

Overview

Integrity signals

Registry

Crossref · 10.1016/j.fertnstert.2011.04.095

Cites

48 of 48 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Verification

Claims the paper makes

0 of 41 cited sources checked · 0 supported · 0 flagged

Show all 16 claims

  • It may state two separate claims as one. 12
  • The quote only partly states this claim. 1
  • Probably not a substantial claim. 5
14 of 14
  • The paper relies on this without support.

    Before this study, the effect of endometriosis symptoms on work productivity had not been measured with standardized instruments.

    “One important aspect of QoL is work productivity; however, the impact of endometriosis symptoms on this particular area has not been quantified to date using standardized instruments.”
    “To our knowledge, WPAI has not been used before to quantify the impact of endometriosis symptoms on work aspects.”
  • The paper relies on this without support.

    Self-reported surgically diagnosed endometriosis in the registry accurately identifies women who have endometriosis.

    “Women (n=193) with self-reported surgically diagnosed endometriosis from the Endometriosis Patient Registry at Ponce School of Medicine and Health Sciences (PSMHS).”
    “patients with self-reported surgically diagnosed of endometriosis (n=715) and controls (n=246)”
  • The paper relies on this without support.

    The Spanish version of EHP-5 used in this study was valid for measuring endometriosis-related HRQoL despite not having been formally translated and validated in Spanish.

    “EHP-5 had not been translated to Spanish, although its questions were derived from SF-36, which has been previously translated to Spanish.”
  • The paper relies on this without support.

    The sample of 193 women from the PSMHS registry is representative of women with endometriosis in Puerto Rico or more broadly.

    “This cross-sectional study on 193 Puerto Rican women with endometriosis supports the evidence gathered by qualitative studies conducted in other populations indicating that endometriosis-related symptoms have a negative impact on QoL, HRQoL, and work productivity.”
  • The paper relies on this without support.

    The WPAI instrument is valid for measuring endometriosis-related work productivity in this population.

    “to our knowledge, this is the first time WPAI has been applied to an endometriosis patient population.”
    “The Work Productivity and Activity Impairment Questionnaire (WPAI) is a validated instrument that measures the effect of both general and specific symptoms on work productivity and daily tasks (34).”
  • The paper relies on this without support.

    The week of the last menstrual period or when symptoms were worse is representative of the typical impact of endometriosis symptoms on work and daily activities.

    “Patients were instructed to respond these questions according to how they felt during the week of their last menstrual period (when exacerbation of symptoms most commonly occurs) or during the week of the month when symptoms were worse.”
  • The paper relies on this without support.

    The 40% response rate did not introduce non-response bias that would alter the findings.

    “The questionnaire was completed by 193 women, for a response rate of 40%.”
7 of 7

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Metadata

Authors
Fourquet, J., Báez, L., Figueroa, M., Iriarte, R. I., & Flores, I.
Affiliations
Ponce Health Sciences University (PR)
Corresponding author
Flores, Idhaliz
Venue
Fertility and Sterility
Publisher
Elsevier BV
Published
2011-07
Volume
96
Issue
1
Pages
107-112
ISSN
0015-0282 (ISSN-L)
OpenAlex
W1964830755
Cited by
262
References
52
Citations by year
2026: 13 · 2025: 24 · 2024: 21 · 2023: 17 · 2022: 16 · 2021: 31 · 2020: 28 · 2019: 9 · 2018: 23 · 2017: 18 · 2016: 14 · 2015: 16 · 2014: 12 · 2013: 12 · 2012: 8
FWCI
11.43
Type
journal article
Language
en
Open access
Locations
  • Fertility and Sterility (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institutes of Health (5s06gm008239-23)
  • National Institute of General Medical Sciences (S06 GM-08239, S06-GM 008239)
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD050559)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
  • Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
  • Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
Keywords
endometriosis, endometriosis symptoms, health-related quality of life, labor productivity, absenteeism, presenteeism, activity impairment, physical and mental health, pelvic pain, infertility, women's health
MeSH terms
Activities of Daily Living, Adolescent, Adult, Cross-Sectional Studies, Efficiency, Endometriosis, Female, Health Status Indicators, Health Surveys, Humans, Middle Aged, Quality of Life, Young Adult

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