Microwave-assisted hydrothermal extraction of sulfated polysaccharides from Ulva spp. and Monostroma latissimum
Abstract
Microwave-assisted hydrothermal extraction was applied for production of sulfated polysaccharides from Ulva spp. and Monostroma latissimum. The maximum ulvan yields attained 40.4±3.2% (Ulva meridionalis) and 36.5±3.1% (Ulva ohnoi) within 4min of come-up time and 10min of extraction time at 160°C, respectively. The rhamnan sulfate yield from M. latissimum further attained 53.1±7.2% at 140°C. The sulfated polysaccharides were easily recovered from the extract by simple ethanol precipitation. In addition, molecular weights and viscosity of the extracted polysaccharides could be controlled by varying the extraction temperature. Dielectric measurement revealed that ionic conduction was the important parameter that affect the microwave susceptibility of algae-water mixture. The sulfated polysaccharides extracts are expected as potential feedstock for medical and food applications.
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Ulvan and rhamnan sulfate exhibit biological activities such as antitumor, anticoagulant, antiviral, and antiherpetic.
“Both of the compounds exhibit biological activities, such as antitumor, anticoagulant, antiviral, and antiherpetic [83].”
From Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae (2018) · cites this paper as [83]
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Self-citation
- Authors
- Tsubaki, S., Oono, K., Hiraoka, M., Onda, A., & Mitani, T.
- Affiliations
- University of Kochi (JP)
- Kyoto University (JP)
- Corresponding author
- Tsubaki, Shuntaro
- Venue
- Food Chemistry
- Publisher
- Elsevier BV
- Published
- 2016-11
- Volume
- 210
- Pages
- 311-316
- ISSN
- 0308-8146 (ISSN-L)
- OpenAlex
- W2344766551
- Cited by
- 150
- References
- 33
- Citations by year
- 2026: 15 · 2025: 12 · 2024: 20 · 2023: 13 · 2022: 20 · 2021: 14 · 2020: 17 · 2019: 14 · 2018: 10 · 2017: 14 · 2016: 1
- FWCI
- 18.71
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Food Chemistry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministry of Education, Culture, Sports, Science and Technology of Japan
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Polysaccharides and Plant Cell Walls
- Keywords
- sulfated polysaccharides, ulvan, Ulva ohnoi, brown algae, extraction temperature, molecular weight control, viscosity, dielectric properties, ionic conduction, ethanol precipitation
- MeSH terms
- Chlorophyta, Deoxy Sugars, Mannans, Microwaves, Polysaccharides, Viscosity, Ulva
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