Bacteria: A New Player in Gastrointestinal Motility Disorders—Infections, Bacterial Overgrowth, and Probiotics
Abstract
Irritable bowel syndrome (IBS) may result from a dysfunctional interaction between the indigenous flora and the intestinal mucosa, which in turn leads to immune activation in the colonic mucosa. Some propose that bacterial overgrowth is a common causative factor in the pathogenesis of symptoms in IBS; others point to evidence suggesting that the cause stems from more subtle qualitative changes in the colonic flora. Bacterial overgrowth will probably prove not to be a major factor in what will eventually be defined as IBS. Nevertheless, short-term therapy with either antibiotics or probiotics seems to reduce symptoms among IBS patients. However, in the long term, safety issues will favor the probiotic approach; results of long-term studies with these agents are eagerly awaited.
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Selected probiotic strains stimulate intestinal peristalsis via mechanisms including decreased intestinal pH, competitive action with intestinal pathogens, and production of substances with neurotransmitter activities.
“The decrease of the intestinal pH [27], a competitive action with intestinal pathogen(s) or production of substances with neurotransmitter activities [28] are some of the mechanisms attributed to selected strains of probiotics which stimulate the intestinal peristalsis.”
Cites
Barbara, G., Stanghellini, V., De Giorgio, R., Cremon, C., Cottrell, G. S., Santini, D., Pasquinelli, G., Morselli-Labate, A. M., Grady, E. F., Bunnett, N. W., et al. (2004) · Gastroenterology · doi:10.1053/j.gastro.2003.11.055 · Cited by 1,475 · see citing works
O’Mahony, L., McCarthy, J., Kelly, P., Hurley, G., Luo, F., Chen, K., O’Sullivan, G. C., Kiely, B., Collins, J. K., Shanahan, F., et al. (2005) · Gastroenterology · doi:10.1053/j.gastro.2004.11.050 · Cited by 1,448 · see citing works
Self-citationSpiller, R. C., Jenkins, D., Thornley, J. P., Hebden, J. M., Wright, T., Skinner, M., & Neal, K. R. (2000) · Gut · doi:10.1136/gut.47.6.804 · Cited by 1,155 · see citing works
Postinfectious Irritable Bowel Syndrome
Spiller, R., & Garsed, K. (2009) · Gastroenterology · doi:10.1053/j.gastro.2009.02.074 · Cited by 1,024 · see citing works
Wigg, A. J., Roberts-Thomson, I. C., Dymock, R. B., McCarthy, P. J., Grose, R. H., & Cummins, A. G. (2001) · Gut · doi:10.1136/gut.48.2.206 · Cited by 836 · see citing works
Activation of the mucosal immune system in irritable bowel syndrome
Chadwick, V. S., Chen, W., Shu, D., Paulus, B., Bethwaite, P., Tie, A., & Wilson, I. (2002) · Gastroenterology · doi:10.1053/gast.2002.33579 · Cited by 833 · see citing works
Vantrappen, G., Janssens, J., Hellemans, J., & Ghoos, Y. (1977) · Journal of Clinical Investigation · doi:10.1172/jci108740 · Cited by 815 · see citing works
Whorwell, P. J., Altringer, L., Morel, J., Bond, Y., Charbonneau, D., O'Mahony, L., Kiely, B., Shanahan, F., & Quigley, E. M. M. (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00734.x · Cited by 799 · see citing works
Self-citationLactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors
Rousseaux, C., Thuru, X., Gelot, A., Barnich, N., Neut, C., Dubuquoy, L., Dubuquoy, C., Merour, E., Geboes, K., Chamaillard, M., et al. (2007) · Nature Medicine · doi:10.1038/nm1521 · Cited by 793 · see citing works
Eradication of Small Intestinal Bacterial Overgrowth Reduces Symptoms of Irritable Bowel Syndrome
Pimentel, M., Chow, E. J., & Lin, H. C. (2000) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.03368.x · Cited by 780 · see citing works
The role of psychological and biological factors in postinfective gut dysfunction
Gwee, K.-A., Leong, Y.-L., Graham, C., McKendrick, M. W., Collins, S. M., Walters, S. J., Underwood, J. E., & Read, N. W. (1999) · Gut · doi:10.1136/gut.44.3.400 · Cited by 764 · see citing works
Malinen, E., Rinttila, T., Kajander, K., Matto, J., Kassinen, A., Krogius, L., Saarela, M., Korpela, R., & Palva, A. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.40312.x · Cited by 699 · see citing works
Pimentel, M., Chow, E. J., & Lin, H. C. (2003) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2003.07234.x · Cited by 670 · see citing works
Immune Activation in Patients With Irritable Bowel Syndrome
Liebregts, T., Adam, B., Bredack, C., Röth, A., Heinzel, S., Lester, S., Downie–Doyle, S., Smith, E., Drew, P., Talley, N. J., et al. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.01.046 · Cited by 660 · see citing works
Dinan, T. G., Quigley, E. M. M., Ahmed, S. M. M., Scully, P., O’Brien, S., O’Mahony, L., O’Mahony, S., Shanahan, F., & Keeling, P. W. N. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.11.033 · Cited by 636 · see citing works
Self-citationRole for protease activity in visceral pain in irritable bowel syndrome
Cenac, N., Andrews, C. N., Holzhausen, M., Chapman, K., Cottrell, G., Andrade-Gordon, P., Steinhoff, M., Barbara, G., Beck, P., Bunnett, N. W., et al. (2007) · Journal of Clinical Investigation · doi:10.1172/jci29255 · Cited by 591 · see citing works
Neal, K. R., Hebden, J., & Spiller, R. (1997) · BMJ · doi:10.1136/bmj.314.7083.779 · Cited by 586 · see citing works
Dunlop, S. P., Jenkins, D., Neal, K. R., & Spiller, R. C. (2003) · Gastroenterology · doi:10.1053/j.gastro.2003.09.028 · Cited by 583 · see citing works
Törnblom, H., Lindberg, G., Nyberg, B., & Veress, B. (2002) · Gastroenterology · doi:10.1053/gast.2002.37059 · Cited by 516 · see citing works
Small intestinal bacterial overgrowth in patients with irritable bowel syndrome
Posserud, I., Stotzer, P.-O., Björnsson, E. S., Abrahamsson, H., & Simrén, M. (2007) · Gut · doi:10.1136/gut.2006.108712 · Cited by 499 · see citing works
Abnormal colonic fermentation in irritable bowel syndrome
King, T. S., Elia, M., & Hunter, J. (1998) · The Lancet · doi:10.1016/s0140-6736(98)02146-1 · Cited by 473 · see citing works
Kim, H. J., Camilleri, M., Mckinzie, S., Lempke, M. B., Burton, D. D., Thomforde, G. M., & Zinsmeister, A. R. (2003) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2003.01543.x · Cited by 468 · see citing works
Pimentel, M., Park, S., Mirocha, J., Kane, S. V., & Kong, Y. (2006) · Annals of Internal Medicine · doi:10.7326/0003-4819-145-8-200610170-00004 · Cited by 466 · see citing works
Psychometric scores and persistence of irritable bowel after infectious diarrhoea
Gwee, K., Read, N. W., Graham, J. C., McKendrick, M. W., Collins, S. M., Marshall, J. S., & Walters, S. J. (1996) · The Lancet · doi:10.1016/s0140-6736(96)90341-4 · Cited by 466 · see citing works
Specific probiotic therapy attenuates antibiotic induced visceral hypersensitivity in mice
Verdú, E. F., Bercik, P., Verma-Gandhu, M., Huang, X.-X., Blennerhassett, P., Jackson, W., Mao, Y., Wang, L., Rochat, F., & Collins, S. M. (2006) · Gut · doi:10.1136/gut.2005.066100 · Cited by 448 · see citing works
Psychometric scores and persistence of irritable bowel after infectious diarrhoea
Ka, G., Graham, J. C., McKendrick, M. W., Collins, S. M., Marshall, J. S., Walters, S., & Read, N. W. (1996) · African journal of medical practice · Cited by 429 · see citing works
Effect of Octreotide on Intestinal Motility and Bacterial Overgrowth in Scleroderma
Soudah, H. C., Hasler, W. L., & Owyang, C. (1991) · New England Journal of Medicine · doi:10.1056/nejm199111213252102 · Cited by 417 · see citing works
Use and abuse of hydrogen breath tests
Simrén, M., & Stotzer, P.-O. (2006) · Gut · doi:10.1136/gut.2005.075127 · Cited by 415 · see citing works
Gwee, K.-A. (2003) · Gut · doi:10.1136/gut.52.4.523 · Cited by 415 · see citing works
Increased risk of irritable bowel syndrome after bacterial gastroenteritis: cohort study
Rodríguez, L. A. G., & Ruigómez, A. (1999) · British medical journal · doi:10.1136/bmj.318.7183.565 · Cited by 409 · see citing works
Mearin, F., Pérez-Oliveras, M., Juan, A. P., Vinyet, J., Ibañez, A., Coderch, J., & Perona, M. C. (2005) · Gastroenterology · doi:10.1053/j.gastro.2005.04.012 · Cited by 406 · see citing works
Kim, H. J., Vazquez Roque, M. I., Camilleri, M., Stephens, D., Burton, D. D., Baxter, K., Thomforde, G., & Zinsmeister, A. R. (2005) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2005.00695.x · Cited by 400 · see citing works
KHALIF, I., QUIGLEY, E., KONOVITCH, E., & MAXIMOVA, I. (2005) · Digestive and Liver Disease · doi:10.1016/j.dld.2005.06.008 · Cited by 382 · see citing works
Self-citationMarshall, J. K., Thabane, M. E., Garg, A. X., Clark, W. F., Salvadori, M. I., & Collins, S. M. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.05.053 · Cited by 370 · see citing works
KAJANDER, K., HATAKKA, K., POUSSA, T., FÄRKKILÄ, M., & KORPELA, R. (2005) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2005.02579.x · Cited by 361 · see citing works
Frapper fort ou doucement:A Gramnegative dilemma.
Hopkin, B. D. A. (1978) · The Lancet · Cited by 358 · see citing works
Spiller, R. E. (2003) · Gastroenterology · doi:10.1016/s0016-5085(03)00324-x · Cited by 353 · see citing works
Sharara, A. I., Aoun, E., Abdul-Baki, H., Mounzer, R., Sidani, S., & ElHajj, I. (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00458.x · Cited by 344 · see citing works
Small Intestinal Bacterial Overgrowth: Roles of Antibiotics, Prebiotics, and Probiotics
Quigley, E. M. M., & Quera, R. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.11.046 · Cited by 328 · see citing works
Self-citationIrritable bowel syndrome—post salmonella infection
McKendrick, M. W., & Read, N. W. (1994) · Journal of Infection · doi:10.1016/s0163-4453(94)94871-2 · Cited by 320 · see citing works
Mättö, J., Maunuksela, L., Kajander, K., Palva, A., Korpela, R., Kassinen, A., & Saarela, M. (2005) · FEMS Immunology & Medical Microbiology · doi:10.1016/j.femsim.2004.08.009 · Cited by 301 · see citing works
Gonsalkorale, W. M., Perrey, C., Pravica, V, Whorwell, P. J., & Hutchinson, I. V. (2003) · Gut · doi:10.1136/gut.52.1.91 · Cited by 273 · see citing works
Bauer, T., Steinbrückner, B., Brinkmann, F., Ditzen, A. K., Schwacha, H., Aponte, J. J., Pelz, K., Kist, M., & Blum, H. E. (2001) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.04668.x · Cited by 266 · see citing works
Chang, C., Chen, G., Lien, H., & Yeh, H. (1998) · Hepatology · doi:10.1002/hep.510280504 · Cited by 261 · see citing works
Kamiya, T., Wang, L., Forsythe, P., Goettsche, G., Mao, Y., Wang, Y., Tougas, G., & Bienenstock, J. (2006) · Gut · doi:10.1136/gut.2005.070987 · Cited by 242 · see citing works
Marshall, J. K., Thabane, M., Borgaonkar, M. R., & James, C. (2007) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2006.11.025 · Cited by 241 · see citing works
Intestinal microecology and quality of life in irritable bowel syndrome patients
Si, J.-M. (2004) · World Journal of Gastroenterology · doi:10.3748/wjg.v10.i12.1802 · Cited by 218 · see citing works
van der Veek, P. P. J., van den Berg, M., de Kroon, Y. E., Verspaget, H. W., & Masclee, A. A. M. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.00257.x · Cited by 217 · see citing works
Small intestinal bacterial overgrowth in human cirrhosis is associated with systemic endotoxemia
Bauer, T. M., Schwacha, H., Steinbruckner, B., Brinkmann, F. E., Ditzen, A. K., Aponte, J. J., Pelz, K., Berger, D., Kist, M., & Blum, H. E. (2002) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2002.05791.x · Cited by 211 · see citing works
Non-alcoholic fatty liver disease: lumen–liver interactions and possible role for probiotics
Solga, S. F., & Diehl, A. M. (2003) · Journal of Hepatology · doi:10.1016/s0168-8278(03)00097-7 · Cited by 210 · see citing works
Nucera, G., Gabrielli, M., Lupascu, A., Lauritano, E. C., Santoliquido, A., Cremonini, F., Cammarota, G., Tondi, P., Pola, P., Gasbarrini, G., et al. (2005) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2005.02493.x · Cited by 204 · see citing works
Gunnarsdóttir, S. A., Sadik, R., Shev, S., Simrén, M., Sjövall, H., Stotzer, P., Abrahamsson, H., Olsson, R., & Bjornsson, E. S. (2003) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2003.07475.x · Cited by 186 · see citing works
Tursi, A., Brandimarte, G., & Giorgetti, G. (2003) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2003.07379.x · Cited by 184 · see citing works
Husebye, E., Skar, V., Høverstad, T., Iversen, T., & Melby, K. K. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90565-0 · Cited by 178 · see citing works
Antibiotics increase functional abdominal symptoms
Maxwell, P., Rink, E., Kumar, D., & Mendall, M. A. (2002) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2002.05428.x · Cited by 176 · see citing works
Walters, B., & Vanner, S. J. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.40795.x · Cited by 172 · see citing works
Pimentel, M., Soffer, E., Chow, E. J., Kong, Y., & Lin, H. C. (2002) · Digestive Diseases and Sciences · doi:10.1023/a:1021039032413 · Cited by 165 · see citing works
Krishnamurthy, S., Kelly, M. M., Rohrmann, C. A., et al. (1983) · PubMed · Cited by 161 · see citing works
Madrid, A. M., Hurtado, C., Venegas, M., Cumsille, F., & Defilippi, C. (2001) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.03636.x · Cited by 158 · see citing works
Krishnamurthy, S., Kelly, M. M., Rohrmann, C. A., et al. (1983) · Gastroenterology · doi:10.1016/0016-5085(83)90005-7 · Cited by 156 · see citing works
Antibiotic use, childhood affluence and irritable bowel syndrome (IBS)
Mendall, M. A., & Kumar, D. (1998) · European Journal of Gastroenterology & Hepatology · doi:10.1097/00042737-199801000-00011 · Cited by 155 · see citing works
Quigley, E. M. M., & Flourie, B. (2007) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2006.00879.x · Cited by 151 · see citing works
Self-citationVan felius, I. D., Akkermans, L. M. A., Bosscha, K., Verheem, A., Harmsen, W., Visser, M. R., & Gooszen, H. G. (2003) · Neurogastroenterology & Motility · doi:10.1046/j.1365-2982.2003.00410.x · Cited by 134 · see citing works
Disorders of gastrointestinal motility: Towards a new classification1
Wingate, D. L., Hongo, M., Kellow, J. E., Lindberg, G., & Smout, A. J. P. M. (2002) · Journal of Gastroenterology and Hepatology · doi:10.1046/j.1440-1746.17.s1.7.x · Cited by 130 · see citing works
Abnormalities in proximal small bowel motility in patients with cirrhosis
Jaime Chesta, R., Defilippi, C., & Defilíppí, C. (1993) · Hepatology · doi:10.1002/hep.1840170513 · Cited by 127 · see citing works
O'Mahony, D., O'Leary, P., & Quigley, E. (2002) · Drugs & Aging · doi:10.2165/00002512-200219070-00005 · Cited by 117 · see citing works
Self-citationDrisko, J., Bischoff, B., Hall, M., & McCallum, R. W. (2006) · Journal of the American College of Nutrition · doi:10.1080/07315724.2006.10719567 · Cited by 111 · see citing works
TSUCHIYA, J., BARRETO, R., OKURA, R., KAWAKITA, S., FESCE, E., & MAROTTA, F. (2004) · Chinese Journal of Digestive Diseases · doi:10.1111/j.1443-9573.2004.00176.x · Cited by 108 · see citing works
Differential regional effects of octreotide on human gastrointestinal motor function.
von der Ohe, M. R., Camilleri, M., Thomforde, G. M., et al. (1995) · Gut · doi:10.1136/gut.36.5.743 · Cited by 106 · see citing works
BACTERIAL OVERGROWTH SYNDROME WITHOUT "BLIND LOOP": A CAUSE FOR MALNUTRITION IN THE ELDERLY
Roberts, S., James, O., & Jarvis, E. (1977) · The Lancet · doi:10.1016/s0140-6736(77)90436-6 · Cited by 101 · see citing works
Small bowel bacterial overgrowth.
Rm, D. (1970) · PubMed · Cited by 100 · see citing works
Dear, K. L. E., Elia, M., & Hunter, J. O. (2005) · Digestive Diseases and Sciences · doi:10.1007/s10620-005-2570-4 · Cited by 97 · see citing works
Sorell, W. T., Quigley, E. M. M., Jin, G., et al. (1993) · Gastroenterology · doi:10.1016/0016-5085(93)90651-r · Cited by 96 · see citing works
Self-citationCuoco, L., & Salvagnini, M. (2006) · PubMed · Cited by 81 · see citing works
A case for an immunological basis for irritable bowel syndrome
Collins, S. M. (2002) · Gastroenterology · doi:10.1053/gast.2002.34097 · Cited by 79 · see citing works
Orocecal Transit Time and Bacterial Overgrowth in Patients with Crohn's Disease
Castiglione, F., Blanco, G. D. V., Rispo, A., Petrelli, G., Amalfi, G., Cozzolino, A., Cuccaro, I., & Mazzacca, G. (2000) · Journal of Clinical Gastroenterology · doi:10.1097/00004836-200007000-00015 · Cited by 77 · see citing works
Bacterial flora in irritable bowel syndrome: role in pathophysiology, implications for management
Quigley, E. M. M. (2007) · Journal of Digestive Diseases · doi:10.1111/j.1443-9573.2007.00277.x · Cited by 67 · see citing works
Self-citationInstability in the faecal flora of a patient suffering from food-related irritable bowel syndrome
BRADLEY, H. K., Wyatt, G. M., Bayliss, C. E., & HUNTER, J. O. (1987) · Journal of Medical Microbiology · doi:10.1099/00222615-23-1-29 · Cited by 65 · see citing works
Quigley, E. M. M., & Thompson, J. S. (1993) · Gastroenterology · doi:10.1016/0016-5085(93)90897-l · Cited by 64 · see citing works
Self-citationIrritable bowel syndrome and inflammatory bowel disease: interrelated diseases?
Quigley, E. M. M. (2005) · Chinese Journal of Digestive Diseases · doi:10.1111/j.1443-9573.2005.00202.x · Cited by 64 · see citing works
Self-citationSerotonergic and non‐serotonergic targets in the pharmacotherapy of visceral hypersensitivity
Bueno, L., De Ponti, F., Fried, M., Kullak‐ublick, G. A., Kwiatek, M. A., Pohl, D., Quigley, E. M. M., Tack, J., & Talley, N. J. (2007) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2006.00876.x · Cited by 64 · see citing works
Self-citationRole of nerves in enteric infection: Table 1
Spiller, R. E. (2002) · Gut · doi:10.1136/gut.51.6.759 · Cited by 64 · see citing works
Clinical gastroenterology and hepatology
Caestecker, J. S. D. (2007) · Gut · doi:10.1136/gut.2007.121491 · Cited by 63 · see citing works
Bittner, A. C., Croffut, R. M., & Stranahan, M. C. (2005) · Clinical Therapeutics · doi:10.1016/j.clinthera.2005.06.005 · Cited by 55 · see citing works
Lactulose breath testing, bacterial overgrowth, and IBS: just a lot of hot air?
Hasler, W. L. (2003) · Gastroenterology · doi:10.1053/j.gastro.2003.08.038 · Cited by 54 · see citing works
Quigley, E. M. M. (2005) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2005.02.010 · Cited by 51 · see citing works
Self-citationSmall bowel bacterial overgrowth, celiac disease, and IBS: what are the real associations?
O’Leary, C., & Quigley, E. M. M. (2003) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2003.07395.x · Cited by 46 · see citing works
Self-citationProbiotics in the Management of Irritable Bowel Syndrome: A Review of Clinical Trials
Hamilton-Miller, J. M. T. (2001) · Microbial Ecology in Health and Disease · doi:10.3402/mehd.v13i4.8025 · Cited by 43 · see citing works
Probiotics in the Management of Irritable Bowel Syndrome: A Review of Clinical Trials
Hamilton-Miller, J. M. T. (2001) · Microbial Ecology in Health and Disease · doi:10.1080/089106001753341282 · Cited by 38 · see citing works
Small bowel disease in the elderly: diarrhoea and malabsorption
Hoffmann, J., & Zeitz, M. (2002) · Best Practice & Research Clinical Gastroenterology · doi:10.1053/bega.2002.0263 · Cited by 34 · see citing works
Germs, Gas and the Gut; the Evolving Role of the Enteric Flora in IBS
Quigley, E. M. M. (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00445.x · Cited by 33 · see citing works
Self-citationSmall intestinal bacterial overgrowth and irritable bowel syndrome
Parisi, G. (2003) · The American Journal of Gastroenterology · doi:10.1016/s0002-9270(03)01719-2 · Cited by 32 · see citing works
Small bowel bacterial overgrowth is not seen in healthy adults but is in disabled older adults.
Mitsui, T., Shimaoka, K., Goto, Y., Kagami, H., Kinomoto, H., Ito, A., & Kondo, T. (2006) · PubMed · Cited by 32 · see citing works
Mitsui, T., Kagami, H., Kinomoto, H., et al. (2003) · Journal of Human Nutrition and Dietetics · doi:10.1046/j.1365-277x.2003.00424.x · Cited by 25 · see citing works
Nieuwenhuijs, Duijvenbode‐Beumer, V., Verheem, Visser, Verhoef, Gooszen, & Akkermans (1999) · European Journal of Clinical Investigation · doi:10.1046/j.1365-2362.1999.00364.x · Cited by 24 · see citing works
Small intestinal bacterial overgrowth and the irritable bowel syndrome
Riordan, S. M., McIver, C. J., Duncombe, V. M., Thomas, M. C., Nagree, A., & Bolin, T. D. (2001) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.04066.x · Cited by 24 · see citing works
Treatment for Bacterial Overgrowth in the Irritable Bowel Syndrome
Drossman, D. A. (2006) · Annals of Internal Medicine · doi:10.7326/0003-4819-145-8-200610170-00012 · Cited by 24 · see citing works
Abnormalities in proximal small bowel motility in patients with cirrhosis,
Chesta, J. (1993) · Hepatology · doi:10.1016/0270-9139(93)90159-k · Cited by 23 · see citing works
Chronic intestinal pseudo-obstruction
Quigley, E. M. M. (1999) · Current Treatment Options in Gastroenterology · doi:10.1007/s11938-999-0063-9 · Cited by 16 · see citing works
Self-citationMishkin, D. S., & Mishkin, S. (2001) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.04064.x · Cited by 13 · see citing works
Jones, M. P., Craig, R. M., & Olinger, E. J. (2001) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.05312.x · Cited by 13 · see citing works
Small intestinal bacterial overgrowth and symptoms of irritable bowel syndrome
Cuoco, L., Cammarota, G., Jorizzo, R. A., et al. (2001) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.03993.x · Cited by 10 · see citing works
Mishkin, D. S. (2001) · The American Journal of Gastroenterology · doi:10.1016/s0002-9270(01)02627-2 · Cited by 6 · see citing works
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Small intestinal bacterial overgrowth syndrome
Bures, J. (2010) · World Journal of Gastroenterology · doi:10.3748/wjg.v16.i24.2978 · Cited by 620 · see citing works
Dimidi, E., Christodoulides, S., Fragkos, K. C., Scott, S. M., & Whelan, K. (2014) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.114.089151 · Cited by 316 · see citing works
Prebiotics and probiotics; modifying and mining the microbiota
Quigley, E. M. M. (2010) · Pharmacological Research · doi:10.1016/j.phrs.2010.01.004 · Cited by 238 · see citing works
Aguilera, M., Cerdà-Cuéllar, M., & Martínez, V (2015) · Gut Microbes · doi:10.4161/19490976.2014.990790 · Cited by 162 · see citing works
Magro, D. O., de Oliveira, L. M. R., Bernasconi, I., de Souza Ruela, M., Credidio, L., Barcelos, I. K., Leal, R. F., Ayrizono, M. D. L. S., Fagundes, J. J., Teixeira, L. D. B., et al. (2014) · Nutrition Journal · doi:10.1186/1475-2891-13-75 · Cited by 105 · see citing works
Quigley, E. M. M. (2011) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2010.12.009 · Cited by 67 · see citing works
Self-citationBehavioral and Complementary Approaches for the Treatment of Irritable Bowel Syndrome
Wald, A., & Rakel, D. (2008) · Nutrition in Clinical Practice · doi:10.1177/0884533608318677 · Cited by 46 · see citing works
A pilot study of colonic B cell pattern in irritable bowel syndrome
Forshammar, J., Isaksson, S., Strid, H., Stotzer, P.-O., Sjövall, H., Simrén, M., & Öhman, L. (2008) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520802272126 · Cited by 33 · see citing works
- Authors
- Quigley, E. M. M.
- Affiliations
- University College Cork (IE)
- Corresponding author
- Quigley, Eamonn M.M.
- ORCID
- Quigley, Eamonn M.M.
- Venue
- Gastroenterology Clinics of North America
- Publisher
- Elsevier BV
- Published
- 2007-09
- Volume
- 36
- Issue
- 3
- Pages
- 735-748
- ISSN
- 0889-8553 (ISSN-L)
- OpenAlex
- W2056321725
- Cited by
- 67
- References
- 104
- Citations by year
- 2025: 1 · 2023: 1 · 2022: 4 · 2020: 3 · 2019: 2 · 2018: 3 · 2017: 8 · 2016: 5 · 2015: 1 · 2014: 5 · 2013: 2 · 2012: 4
- FWCI
- 1.02
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Gastroenterology Clinics of North America (publishedVersion)
- PubMed (publishedVersion)
- Lenus, The Irish Health Repository (Dr Steevens Hospital Library) (submittedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Keywords
- irritable bowel syndrome, bacterial overgrowth, probiotics, gut microbiota, gastrointestinal motility disorders, intestinal infection, colonic mucosa, immune activation, antibiotic therapy, probiotic safety
- MeSH terms
- Bacteria, Bacterial Infections, Gastrointestinal Diseases, Humans, Probiotics, Gastrointestinal Tract
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