Candida auris : An emerging multidrug-resistant pathogen
Open accessAbstract
Candida aurisis an emerging multidrug-resistant pathogen that can be difficult to identify using traditional biochemical methods. C. auris is capable of causing invasive fungal infections, particularly among hospitalized patients with significant medical comorbidities. Echinocandins are the empiric drugs of choice for C. auris, although not all isolates are susceptible and resistance may develop on therapy. Nosocomial C. auris outbreaks have been reported in a number of countries and aggressive infection control measures are paramount to stopping transmission.
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The pitavastatin-fluconazole interactions were not sufficient to restore fluconazole activity in several fluconazole-resistant isolates; two C. albicans and four C. auris isolates maintained their resistance profiles to fluconazole.
“Of note, although pitavastatin was able to demonstrate broad-spectrum synergistic interactions with fluconazole, these interactions were not sufficient to restore the antifungal activity of fluconazole in several fluconazole-resistant isolates. Considering the current resistance breakpoints for azole drugs, two C. albicans and four C. auris isolates maintained their resistance profiles to fluconaz”
From Repurposing approach identifies pitavastatin as a potent azole chemosensitizing agent effective against azole-resistant Candida species (2020) · cites this paper as [35]
C. auris is an emerging fungal pathogen implicated in numerous global outbreaks of life-threatening candidemia, leading to significant morbidity and high mortality.
“Candida auris is an emerging fungal pathogen that has been recently implicated in numerous global outbreaks of life-threatening candidemia, leading to significant morbidity and high rates of mortality [1,2].”
Cites
Lockhart, S. R., Etienne, K. A., Vallabhaneni, S., Farooqi, J., Chowdhary, A., Govender, N. P., Colombo, A. L., Calvo, B., Cuomo, C. A., Desjardins, C. A., et al. (2017) · Clinical Infectious Diseases · doi:10.1093/cid/ciw691 · Cited by 1,662 · see citing works
Satoh, K., Makimura, K., Hasumi, Y., Nishiyama, Y., Uchida, K., & Yamaguchi, H. (2009) · Microbiology and Immunology · doi:10.1111/j.1348-0421.2008.00083.x · Cited by 1,381 · see citing works
First hospital outbreak of the globally emerging Candida auris in a European hospital
Schelenz, S., Hagen, F., Rhodes, J. L., Abdolrasouli, A., Chowdhary, A., Hall, A., Ryan, L., Shackleton, J., Trimlett, R., Meis, J. F., et al. (2016) · Antimicrobial Resistance & Infection Control · doi:10.1186/s13756-016-0132-5 · Cited by 768 · see citing works
Chowdhary, A., Sharma, C., & Meis, J. F. (2017) · PLOS Pathogens · doi:10.1371/journal.ppat.1006290 · Cited by 750 · see citing works
Kathuria, S., Singh, P. K., Sharma, C., Prakash, A., Masih, A., Kumar, A., Meis, J. F. G. M., & Chowdhary, A. (2015) · Journal of Clinical Microbiology · doi:10.1128/jcm.00367-15 · Cited by 536 · see citing works
First Three Reported Cases of Nosocomial Fungemia Caused by Candida auris
Lee, W. G., Shin, J. H., Uh, Y., Kang, M. G., Kim, S. H., Park, K. H., & Jang, H. (2011) · Journal of Clinical Microbiology · doi:10.1128/jcm.00319-11 · Cited by 524 · see citing works
Calvo, B., Melo, A. S. D. A., Mena, A. J. P., Hernandez, M., Francisco, E. C., Hagen, F., Meis, J. F. G. M., & Colombo, A. L. (2016) · Journal of Infection · doi:10.1016/j.jinf.2016.07.008 · Cited by 448 · see citing works
New Clonal Strain ofCandida auris, Delhi, India
Chowdhary, A., Sharma, C., Duggal, S., Agarwal, K., Prakash, A., Singh, P. K., Jain, S., Kathuria, S., Randhawa, H. S., Hagen, F., et al. (2013) · Emerging infectious diseases · doi:10.3201/eid1910.130393 · Cited by 418 · see citing works
Larkin, E., Hager, C., Chandra, J., Mukherjee, P. K., Retuerto, M., Salem, I., Long, L., Isham, N., Kovanda, L., Borroto-Esoda, K., et al. (2017) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02396-16 · Cited by 395 · see citing works
Multidrug-resistant endemic clonal strain of Candida auris in India
Chowdhary, A., Anil Kumar, V., Sharma, C., Prakash, A., Agarwal, K., Babu, R., Dinesh, K. R., Karim, S., Singh, S. K., Hagen, F., et al. (2014) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-013-2027-1 · Cited by 373 · see citing works
Candida auris candidaemia in Indian ICUs: analysis of risk factors
Rudramurthy, S. M., Chakrabarti, A., Paul, R. A., Sood, P., Kaur, H., Capoor, M. R., Kindo, A. J., Marak, R. S. K., Arora, A., Sardana, R., et al. (2017) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkx034 · Cited by 357 · see citing works
Borman, A. M., Szekely, A., & Johnson, E. M. (2016) · mSphere · doi:10.1128/msphere.00189-16 · Cited by 333 · see citing works
Kim, M., Shin, J. H., Sung, H., Lee, K., Kim, E.-C., Ryoo, N. H., Lee, J., Jung, S., Park, K. H., Kee, S., et al. (2009) · Clinical Infectious Diseases · doi:10.1086/597108 · Cited by 310 · see citing works
Vallabhaneni, S., Kallen, A., Tsay, S., Chow, N., Welsh, R., Kerins, J., Kemble, S. K., Pacilli, M., Black, S. R., Landon, E., et al. (2016) · MMWR. Morbidity and Mortality Weekly Report · doi:10.15585/mmwr.mm6544e1 · Cited by 302 · see citing works
Multidrug-Resistant <i>Candida haemulonii</i> and <i>C. auris</i> , Tel Aviv, Israel
Ben-Ami, R., Berman, J., Novikov, A., Bash, E., Shachor-Meyouhas, Y., Zakin, S., Maor, Y., Tarabia, J., Schechner, V., Adler, A., et al. (2017) · Emerging Infectious Diseases · doi:10.3201/eid2302.161486 · Cited by 297 · see citing works
Arendrup, M. C., Prakash, A., Meletiadis, J., Sharma, C., & Chowdhary, A. (2017) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00485-17 · Cited by 270 · see citing works
<i>Candida auris</i>–Associated Candidemia, South Africa
Magobo, R. E., Corcoran, C., Seetharam, S., & Govender, N. P. (2014) · Emerging Infectious Diseases · doi:10.3201/eid2007.131765 · Cited by 259 · see citing works
Invasive Infections with Multidrug-Resistant Yeast Candida auris , Colombia
Morales-López, S. E., Parra‐Giraldo, C. M., Ceballos-Garzón, A., Martínez, H. P., Rodríguez, G. J., Álvarez, C., & Rodríguez, J. Y. (2016) · Emerging infectious diseases · doi:10.3201/eid2301.161497 · Cited by 244 · see citing works
Piedrahita, C. T., Cadnum, J. L., Jencson, A. L., Shaikh, A., Ghannoum, M. A., & Donskey, C. J. (2017) · Infection Control and Hospital Epidemiology · doi:10.1017/ice.2017.127 · Cited by 223 · see citing works
Effectiveness of Disinfectants Against Candida auris and Other Candida Species
Cadnum, J. L., Shaikh, A., Piedrahita, C. T., Thriveen Sankar, C., Jencson, A. L., Larkin, E. L., Ghannoum, M. A., & Donskey, C. J. (2017) · Infection Control and Hospital Epidemiology · doi:10.1017/ice.2017.162 · Cited by 209 · see citing works
Kordalewska, M., Zhao, Y., Lockhart, S. R., Chowdhary, A., Berrío, I., & Perlin, D. S. (2017) · Journal of Clinical Microbiology · doi:10.1128/jcm.00630-17 · Cited by 195 · see citing works
Candida aurisCandidemia in Kuwait, 2014
Emara, M., Ahmad, S., Khan, Z., Joseph, L., Al-Obaid, I., Purohit, P., & Bafna, R. (2015) · Emerging infectious diseases · doi:10.3201/eid2106.150270 · Cited by 185 · see citing works
Prakash, A., Sharma, C., Singh, A. K., Singh, P. K., Kumar, A., Hagen, F., Govender, N. P., Colombo, A. L., Meis, J. F. G. M., & Chowdhary, A. (2015) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2015.10.022 · Cited by 167 · see citing works
Tsay, S. V., Welsh, R. M., Adams, E. H., Chow, N. A., Gade, L., Berkow, E. L., Poirot, E., Lutterloh, E. C., Quinn, M., Chaturvedi, S., et al. (2017) · MMWR Morbidity and Mortality Weekly Report · doi:10.15585/mmwr.mm6619a7 · Cited by 160 · see citing works
Nosocomial fungemia by Candida auris: First four reported cases in continental Europe
Gaitán, A. C. R., Moret, A. M., Hontangas, J. L. L., Molina, J. M. R., López, A., Hernández-Cabezas, A., Maseres, J. B. M., Chouman-Arcas, R., Ruiz, M. D. G., Chiveli, M.-A., et al. (2017) · Revista Iberoamericana de Micología · doi:10.1016/j.riam.2016.11.002 · Cited by 158 · see citing works
Current perspective on emergence, diagnosis and drug resistance in Candida auris
Sarma, S., & Upadhyay, S. (2017) · Infection and Drug Resistance · doi:10.2147/idr.s116229 · Cited by 147 · see citing works
Oh, B. J., Shin, J. H., Kim, M., Sung, H., Lee, K., Joo, M. Y., Shin, M., Suh, S., & Ryang, D. W. (2010) · Medical Mycology · doi:10.3109/13693786.2010.493563 · Cited by 143 · see citing works
Berkow, E. L., Angulo, D. A., & Lockhart, S. R. (2017) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00435-17 · Cited by 103 · see citing works
Pharmacodynamic Optimization for Treatment of Invasive Candida auris Infection
Lepak, A. J., Zhao, M., Berkow, E. L., Lockhart, S. R., & Andes, D. R. (2017) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00791-17 · Cited by 92 · see citing works
Candidemia caused by amphotericin B and Fluconazole resistant Candida auris
Sarma, S., Kumar, N., Sharma, S., Govil, D., Ali, T., Mehta, Y. B., & Rattan, A. (2013) · Indian Journal of Medical Microbiology · doi:10.4103/0255-0857.108746 · Cited by 91 · see citing works
Al-Siyabi, T., Busaidi, I. A., Balkhair, A., Muharrmi, Z. A., Al-Salti, M., & Adawi, B. A. (2017) · Journal of Infection · doi:10.1016/j.jinf.2017.05.016 · Cited by 88 · see citing works
Kumar, A., Sachu, A., Mohan, K., Vinod, V., Dinesh, K. R., & Karim, S. (2017) · Revista Iberoamericana de Micología · doi:10.1016/j.riam.2016.11.004 · Cited by 60 · see citing works
Otomastoiditis caused by Candida auris: Case report and literature review
Choi, H. I., An, J. Y., Hwang, J. J., Moon, S., & Son, J. S. (2017) · Mycoses · doi:10.1111/myc.12617 · Cited by 51 · see citing works
Khillan, V., Rathore, N., Kathuria, S., & Chowdhary, A. (2014) · JMM Case Reports · doi:10.1099/jmmcr.0.t00018 · Cited by 45 · see citing works
Flagged first, then by citations
2 of the 36 references couldn’t be matched to a known paper.
Cited by
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Ruiz‐Gaitán, A., Moret, A. M., Tasias‐Pitarch, M., Aleixandre‐López, A. I., Martínez‐Morel, H., Calabuig, E., Salavert‐Lletí, M., Ramírez, P., López‐Hontangas, J. L., Hagen, F., et al. (2018) · Mycoses · doi:10.1111/myc.12781 · Cited by 343 · see citing works
McArthur, D. B. (2019) · Nursing Clinics of North America · doi:10.1016/j.cnur.2019.02.006 · Cited by 253 · see citing works
Candida auris—the growing menace to global health
Lone, S. A., & Ahmad, A. (2019) · Mycoses · doi:10.1111/myc.12904 · Cited by 210 · see citing works
An Update on the Roles of Non-albicans Candida Species in Vulvovaginitis
Makanjuola, O., Bongomin, F., & Fayemiwo, S. (2018) · Journal of Fungi · doi:10.3390/jof4040121 · Cited by 182 · see citing works
Segal, E. S., Gritsenko, V., Levitan, A., Yadav, B., Dror, N., Steenwyk, J. L., Silberberg, Y., Mielich, K., Rokas, A., Gow, N. A. R., et al. (2018) · mBio · doi:10.1128/mbio.02048-18 · Cited by 150 · see citing works
Candida auris: Epidemiology, risk factors, virulence, resistance, and therapeutic options
Sardi, J. D. C. O., Silva, D. R., Mendes‐Giannini, M. J. S., & Rosalen, P. L. (2018) · Microbial Pathogenesis · doi:10.1016/j.micpath.2018.09.014 · Cited by 132 · see citing works
Fungal Lanosterol 14α-demethylase: A target for next-generation antifungal design
Monk, B. C., Sagatova, A. A., Hosseini, P., Ruma, Y. N., Wilson, R. K., & Keniya, M. V. (2019) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2019.02.008 · Cited by 136 · see citing works
Lara, H. H., Ixtepan-Turrent, L., Jose Yacaman, M., & Lopez-Ribot, J. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b20708 · Cited by 116 · see citing works
Khan, Z., Ahmad, S., Al-Sweih, N., Joseph, L., Alfouzan, W., & Asadzadeh, M. (2018) · PLOS ONE · doi:10.1371/journal.pone.0195743 · Cited by 109 · see citing works
Regulation of C-Type Lectin Receptor-Mediated Antifungal Immunity
Tang, J., Lin, G., Langdon, W. Y., Tao, L., & Zhang, J. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00123 · Cited by 109 · see citing works
An Overview on Candida auris in Healthcare Settings
Cristina, M. L., Spagnolo, A. M., Sartini, M., Carbone, A., Oliva, M., Schinca, E., Boni, S., & Pontali, E. (2023) · Journal of Fungi · doi:10.3390/jof9090913 · Cited by 104 · see citing works
Review on Current Status of Echinocandins Use
Mroczyńska, M., & Brillowska‐Dąbrowska, A. (2020) · Antibiotics · doi:10.3390/antibiotics9050227 · Cited by 108 · see citing works
Bhattacharya, S., Holowka, T., Orner, E. P., & Fries, B. C. (2019) · Scientific Reports · doi:10.1038/s41598-019-41513-6 · Cited by 104 · see citing works
Adhesins of Yeasts: Protein Structure and Interactions
Willaert, R. (2018) · Journal of Fungi · doi:10.3390/jof4040119 · Cited by 92 · see citing works
Wall, G., Chaturvedi, A. K., Wormley, F. L., Wiederhold, N. P., Patterson, H. P., Patterson, T. F., & Lopez-Ribot, J. L. (2018) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01084-18 · Cited by 89 · see citing works
Biofilm formation by <i>Candida auris</i> isolated from colonising sites and candidemia cases
Singh, R., Kaur, M., Chakrabarti, A., Shankarnarayan, S. A., & Rudramurthy, S. M. (2019) · Mycoses · doi:10.1111/myc.12947 · Cited by 86 · see citing works
Zhang, S. X., Babady, N. E., Hanson, K. E., Harrington, A., Larkin, P. M. K., Leal, S. M., Luethy, P. M., Martin, I. W., Pancholi, P., Procop, G. W., et al. (2021) · Journal of Clinical Microbiology · doi:10.1128/jcm.01784-20 · Cited by 87 · see citing works
Antibiofilm Activities of Biogenic Silver Nanoparticles Against Candida albicans
Ahamad, I., Bano, F., Anwer, R., Srivastava, P., Kumar, R., & Fatma, T. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.741493 · Cited by 86 · see citing works
Drug Resistance and Novel Therapeutic Approaches in Invasive Candidiasis
Murphy, S. E., & Bicanic, T. A. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.759408 · Cited by 85 · see citing works
Tran, H. N. H., Graham, L., & Adukwu, E. C. (2020) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-020-10829-z · Cited by 82 · see citing works
Yamashita, K., Miyazaki, T., Fukuda, Y., Mitsuyama, J., Saijo, T., Shimamura, S., Yamamoto, K., Imamura, Y., Izumikawa, K., Yanagihara, K., et al. (2019) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00374-19 · Cited by 77 · see citing works
In-silico design of a multivalent epitope-based vaccine against Candida auris
Akhtar, N., Joshi, A., Kaushik, V., Kumar, M., & Mannan, M. A.-U. (2021) · Microbial Pathogenesis · doi:10.1016/j.micpath.2021.104879 · Cited by 71 · see citing works
Alatoom, A. A., Sartawi, M., Lawlor, K., AbdelWareth, L., Thomsen, J., Nusair, A. R., & Mirza, I. R. (2018) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2018.02.005 · Cited by 72 · see citing works
de Oliveira, H. C., Monteiro, M. C., Rossi, S. A., Pemán, J., Gaitán, A. C. R., Mendes‐Giannini, M. J. S., Mellado, E., & Zaragoza, Ó. (2019) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2019.00083 · Cited by 67 · see citing works
Iguchi, S., Itakura, Y., Yoshida, A., Kamada, K., Mizushima, R., Arai, Y., Uzawa, Y., & Kikuchi, K. (2019) · Journal of Infection and Chemotherapy · doi:10.1016/j.jiac.2019.05.034 · Cited by 70 · see citing works
Allert, S., Schulz, D., Kämmer, P., Großmann, P., Wolf, T., Schäuble, S., Panagiotou, G., Brunke, S., & Hube, B. (2022) · Virulence · doi:10.1080/21505594.2022.2026037 · Cited by 66 · see citing works
Vatanshenassan, M., Boekhout, T., Meis, J. F. G. M., Berman, J. G., Chowdhary, A., Ben‐Ami, R., Sparbier, K., & Kostrzewa, M. (2019) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2019.00020 · Cited by 66 · see citing works
Different efficacies of common disinfection methods against candida auris and other candida species
Fu, L., Le, T., Liu, Z., Wang, L., Guo, H., Yang, J., Chen, Q., & Hu, J. (2020) · Journal of Infection and Public Health · doi:10.1016/j.jiph.2020.01.008 · Cited by 63 · see citing works
Vazquez-Munoz, R., Lopez, F. D., & Lopez-Ribot, J. L. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.01673 · Cited by 59 · see citing works
Wall, G., Herrera, N., & Lopez-Ribot, J. L. (2019) · Journal of Fungi · doi:10.3390/jof5040092 · Cited by 58 · see citing works
Eldesouky, H. E., Salama, E. A., Li, X., Hazbun, T. R., Mayhoub, A. S., & Seleem, M. N. (2020) · Scientific Reports · doi:10.1038/s41598-020-64571-7 · Cited by 55 · see citing works
The potential of respiration inhibition as a new approach to combat human fungal pathogens
Duvenage, L., Munro, C. A., & Gourlay, C. W. (2019) · Current Genetics · doi:10.1007/s00294-019-01001-w · Cited by 53 · see citing works
Billamboz, M., Fatima, Z., Hameed, S., & Jawhara, S. (2021) · Microorganisms · doi:10.3390/microorganisms9030634 · Cited by 53 · see citing works
Gaitán, A. C. R., Fernández-Pereira, J., Valentı́n, E., Tormo‐Más, M. Á., Eraso, E., Pemán, J., & de Groot, P. W. J. (2018) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2018.06.014 · Cited by 50 · see citing works
Dudiuk, C., Berrío, I., Leonardelli, F., Morales-López, S. E., Theill, L., Macedo, D., Rodríguez, J. Y., Salcedo, S., Marín, A., Gamarra, S. P., et al. (2019) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkz178 · Cited by 47 · see citing works
Bennett, S., Said, L. B., Lacasse, P., Malouin, F., & Fliss, I. (2021) · Antibiotics · doi:10.3390/antibiotics10111418 · Cited by 47 · see citing works
Candida auris: A Mini Review on Epidemiology in Healthcare Facilities in Asia
Thatchanamoorthy, N., Rukumani, D. V., Samudi, C., & Tay, S. T. (2022) · Journal of Fungi · doi:10.3390/jof8111126 · Cited by 48 · see citing works
Semreen, M. H., Soliman, S. S. M., Saeed, B. Q., Alqarihi, A., Uppuluri, P., & Ibrahim, A. S. (2019) · Molecules · doi:10.3390/molecules24030399 · Cited by 46 · see citing works
Emerging Issues in Antifungal Resistance
Perfect, J. R., & Ghannoum, M. A. (2020) · Infectious Disease Clinics of North America · doi:10.1016/j.idc.2020.05.003 · Cited by 44 · see citing works
Araujo, J. T. C. D., Martin-Pastor, M., Pérez, L., Pinazo, A., & Sousa, F. F. O. D. (2021) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2021.115808 · Cited by 46 · see citing works
Vázquez-Muñoz, R., Lopez, F. D., & Lopez-Ribot, J. L. (2020) · Antibiotics · doi:10.3390/antibiotics9080461 · Cited by 43 · see citing works
Farnesol increases the activity of echinocandins against Candida auris biofilms
Nagy, F., Tóth, Z., Daróczi, L., Székely, A., Borman, A. M., Majoros, L., & Kovács, R. (2019) · Medical Mycology · doi:10.1093/mmy/myz057 · Cited by 41 · see citing works
Update on invasive fungal infections in the Middle Eastern and North African region
Osman, M., Al Bikai, A., Rafei, R., Mallat, H., Dabboussi, F., & Hamze, M. (2020) · Brazilian Journal of Microbiology · doi:10.1007/s42770-020-00325-x · Cited by 39 · see citing works
Antifungal Development and the Urgency of Minimizing the Impact of Fungal Diseases on Public Health
de Oliveira, H. C., Bezerra, B. T., & Rodrigues, M. L. (2022) · ACS Bio & Med Chem Au · doi:10.1021/acsbiomedchemau.2c00055 · Cited by 41 · see citing works
Microbial Air Quality in Healthcare Facilities
Bonadonna, L., Briancesco, R., Coccia, A. M., Meloni, P., Rosa, G. L., & Moscato, U. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18126226 · Cited by 39 · see citing works
García-Carnero, L. C., Pérez-García, L. A., Martínez-Álvarez, J. A., Reyes-Martínez, J. E., & Mora-Montes, H. M. (2018) · Infection and Drug Resistance · doi:10.2147/idr.s170337 · Cited by 38 · see citing works
Eldesouky, H. E., Lanman, N. A., Hazbun, T. R., & Seleem, M. N. (2020) · Virulence · doi:10.1080/21505594.2020.1838741 · Cited by 37 · see citing works
NO Candida auris: Nitric Oxide in Nanotherapeutics to Combat Emerging Fungal Pathogen Candida auris
Cleare, L. G., Li, K. L., Abuzeid, W. M., Nacharaju, P., Friedman, J. M., & Nosanchuk, J. D. (2020) · Journal of Fungi · doi:10.3390/jof6020085 · Cited by 36 · see citing works
Candida Pathogenicity and Interplay with the Immune System
Valand, N., & Girija, U. V. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-67452-6_11 · Cited by 36 · see citing works
Targeting intrinsic cell death pathways to control fungal pathogens
Kulkarni, M., Stolp, Z. D., & Hardwick, J. M. (2019) · Biochemical Pharmacology · doi:10.1016/j.bcp.2019.01.012 · Cited by 30 · see citing works
Successful treatment of C. auris shunt infection with intraventricular caspofungin
Singhal, T., Kumar, A., Borade, P. S., Shah, S., & Soman, R. N. (2018) · Medical Mycology Case Reports · doi:10.1016/j.mmcr.2018.08.005 · Cited by 32 · see citing works
Experience of treating Candida auris cases at a general hospital in the state of Qatar
Shaukat, A., Ansari, N. A., Al-Wali, W., Karic, E., Madhoun, I. E., Mitwally, H., Hamed, M. M. M., & Visan, F. (2020) · IDCases · doi:10.1016/j.idcr.2020.e01007 · Cited by 30 · see citing works
Prolonged Outbreak of Candida krusei Candidemia in Paediatric Ward of Tertiary Care Hospital
Kaur, H., Shankarnarayana, S. A., Hallur, V., Jayashree, M., Biswal, M., Ghosh, A. K., Ray, P., Chakrabarti, A., & Rudramurthy, S. M. (2020) · Mycopathologia · doi:10.1007/s11046-020-00427-y · Cited by 30 · see citing works
Monk, B. C., & Keniya, M. V. (2021) · Journal of Fungi · doi:10.3390/jof7020067 · Cited by 30 · see citing works
Müller, P., Tan, C., Ißleib, U., Paßvogel, L., Eilts, B., & Steinhauer, K. (2020) · Journal of Hospital Infection · doi:10.1016/j.jhin.2020.05.026 · Cited by 28 · see citing works
Alvarado, M. I., Álvarez, J. B., Lockhart, S. R., Valentı́n, E., Gaitán, A. C. R., Eraso, E., & de Groot, P. W. J. (2020) · Mycoses · doi:10.1111/myc.13204 · Cited by 27 · see citing works
First reported outbreak of the emerging pathogen Candida auris in Canada
Eckbo, E. J., Wong, T., Bharat, A., Cameron-Lane, M., Hoang, L., Dawar, M., & Charles, M. (2021) · American Journal of Infection Control · doi:10.1016/j.ajic.2021.01.013 · Cited by 27 · see citing works
Recent advances and future perspectives in the pharmacological treatment ofCandida aurisinfections
Giacobbe, D. R., Magnasco, L., Sepulcri, C., Mikulska, M., Koehler, P. A., Cornely, O. A., & Bassetti, M. (2021) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2021.1949285 · Cited by 27 · see citing works
Skin and hard surface disinfection against Candida auris – What we know today
Omardien, S., & Teska, P. J. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2024.1312929 · Cited by 29 · see citing works
Satała, D., Juszczak, M., Wronowska, E., Surowiec, M., Kulig, K., Kozik, A., Rąpała‐Kozik, M., & Karkowska‐Kuleta, J. (2022) · Cellular Microbiology · doi:10.1155/2022/2599136 · Cited by 26 · see citing works
Genetic Modification of Closely Related Candida Species
Mancera, E., Frazer, C., Porman, A. M., Ruiz‐Castro, S., Johnson, A. D., & Bennett, R. J. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00357 · Cited by 22 · see citing works
Alobaid, K., & Khan, Z. (2018) · Journal de Mycologie Médicale · doi:10.1016/j.mycmed.2018.12.001 · Cited by 21 · see citing works
The efficacy of pulsed-xenon ultraviolet light technology on Candida auris
Maslo, C., du Plooy, M., & Coetzee, J. (2019) · BMC Infectious Diseases · doi:10.1186/s12879-019-4137-6 · Cited by 22 · see citing works
Candida auris in Austria—What Is New and What Is Different
Spettel, K., Kriz, R., Wu, C. C., Achter, L., Schmid, S., Galazka, S., Selitsch, B., Camp, I., Makristathis, A., Lagler, H., et al. (2023) · Journal of Fungi · doi:10.3390/jof9020129 · Cited by 18 · see citing works
Candida endocarditis: Update on management considerations
Jamil, Y., Akinleye, A. A., Mirzaei, M., Lempel, M., Farhat, K., & Pan, S. (2023) · World Journal of Cardiology · doi:10.4330/wjc.v15.i10.469 · Cited by 21 · see citing works
First case of Candida auris infection in Belgium in a surgical patient from Kuwait
Dewaele, K., Frans, J., Smismans, A., Ho, E., Tollens, T., & Lagrou, K. (2018) · Acta Clinica Belgica · doi:10.1080/17843286.2018.1555114 · Cited by 18 · see citing works
The Role of Antifungals in Pediatric Critical Care Invasive Fungal Infections
Kaushik, A., & Kest, H. (2018) · Critical Care Research and Practice · doi:10.1155/2018/8469585 · Cited by 17 · see citing works
Dekkerová, J., Lopez-Ribot, J. L., & Bujdáková, H. (2018) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-018-3400-x · Cited by 17 · see citing works
Paulovičová, E., Paulovičová, L., Farkaš, P., Karelin, A. A., Tsvetkov, Y. E., Krylov, V. B., & Nifantiev, N. E. (2019) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2019.00378 · Cited by 16 · see citing works
Rodrigues, L. S., Gazara, R. K., Passarelli‐Araujo, H., Valengo, A. E., Pontes, P. V. M., da Fonseca, R. N., de Souza, R. F., Venâncio, T. M., & Dalla-Costa, L. M. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.01535 · Cited by 17 · see citing works
Gülten, E., Çınar, G., Sarıcaoğlu, E. M., Kalkan, İ. A., Yılmaz, A. Z., Saldere, E. H., & Yörük, F. (2025) · Journal of Fungi · doi:10.3390/jof11080552 · Cited by 16 · see citing works
Sarvestani, H. K., Mahmoudi, S., Khaki, P. A., Ansari, S., Ghaderkhani, S., Roostaei, D., Ghazvini, R. D., Hashemi, S. J., Rafat, Z., & Abollahi, A. (2022) · Current Medical Mycology · doi:10.18502/cmm.7.4.8406 · Cited by 16 · see citing works
Politi, L., Vrioni, G., Hatzianastasiou, S., Lada, M., Martsoukou, M., Sipsas, N. V., Chini, M., Baka, V., Kafkoula, E., Masgala, A., et al. (2024) · Journal de Mycologie Médicale · doi:10.1016/j.mycmed.2024.101477 · Cited by 15 · see citing works
Szibor, M., Schenkl, C., Barsottini, M. R. D. O., Young, L., & Moore, A. L. (2022) · Biochemical Journal · doi:10.1042/bcj20180192 · Cited by 15 · see citing works
Superenhanced Removal of Fungal Biofilms by Protease‐Functionalized Amphotericin B Nanocarriers
Weldrick, P. J., Hardman, M. J., & Paunov, V. N. (2020) · Advanced NanoBiomed Research · doi:10.1002/anbr.202000027 · Cited by 14 · see citing works
First Detection of Emergent Fungal Pathogen Candida auris in Khartoum State, Sudan
Badri, A. M. (2019) · American Journal of Biomedical Science & Research · doi:10.34297/ajbsr.2019.06.000982 · Cited by 13 · see citing works
Primer aislamiento de Candida auris en Chile
Moreno, M. V., Simian, M. E., Villarroel, J., Fuenzalida, L. M., Yarad, M. F., Soto, A., Silva, V., & Pimentel, X. (2019) · Revista chilena de infectología · doi:10.4067/s0716-10182019000600767 · Cited by 14 · see citing works
Progress and Challenges in the Management of Nursing Home Infections
Sloane, P. D., Zimmerman, S. I., & Nace, D. A. (2019) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2019.11.025 · Cited by 13 · see citing works
Sana, F., Hussain, W., Zaman, G., Satti, L., Khurshid, U., & Khadim, M. T. (2019) · Journal of Hospital Infection · doi:10.1016/j.jhin.2019.06.011 · Cited by 12 · see citing works
Oyardı, Ö., Demir, E. S., Alkan, B., Kömeç, S., Genç, G. E., Aygün, G., Teke, L., Turan, D., Erturan, Z., Savage, P. B., et al. (2023) · Journal of Fungi · doi:10.3390/jof9101026 · Cited by 11 · see citing works
Emerging Pathogens of the Candida Species
Yang, B., & Rao, R. P. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.80378 · Cited by 10 · see citing works
Advancing Antimicrobial Resistance Research Through Quantitative Modeling and Synthetic Biology
Farquhar, K. S., Flohr, H., & Charlebois, D. A. (2020) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2020.583415 · Cited by 9 · see citing works
Guthrie, J. D., & Charlebois, D. A. (2022) · Physical Biology · doi:10.1088/1478-3975/ac8c17 · Cited by 10 · see citing works
Alastruey‐Izquierdo, A., Asensio, Á., Besolí, A., Calabuig, E., Fernández‐Ruiz, M., García‐Vidal, C., Gasch, O., Guinea, J., Martín-Gómez, M. T., Paño, J. R., et al. (2019) · Revista Iberoamericana de Micología · doi:10.1016/j.riam.2019.06.001 · Cited by 9 · see citing works
Fiala, J., Roach, T., Holzinger, A., Husiev, Y., Delueg, L., Hammerle, F. J., Armengol, E. S., Schöbel, H., Bonnet, S. A., Laffleur, F., et al. (2024) · Planta Medica · doi:10.1055/a-2249-9110 · Cited by 7 · see citing works
Torres, S. R., Kim, H. C., Leach, L., Chaturvedi, S., Bennett, C. J., Hill, D. J., & Jesus, M. D. (2019) · Journal of Occupational and Environmental Hygiene · doi:10.1080/15459624.2019.1594840 · Cited by 7 · see citing works
Chauhan, V., Kumar, A., Tripathi, S., Jha, M., Kumar, N., Poluri, K. M., & Gupta, P. (2024) · Discover Public Health · doi:10.1186/s12982-024-00274-y · Cited by 7 · see citing works
Hassan, Y., & Sule, H. (2023) · Academia Biology · doi:10.20935/acadbiol6074 · Cited by 6 · see citing works
Candida auris: Antifungal Multi-Resistant Emerging Yeast
Dolande, M., García, N., Capote, A. M., Panizo, M. M., Ferrara, G., & Alarcón, V. (2017) · Current Fungal Infection Reports · doi:10.1007/s12281-017-0299-0 · Cited by 6 · see citing works
Fungal endocarditis: microbial insights, diagnostic and therapeutic challenges in the modern era
Edpuganti, S. (2025) · Exploration of Cardiology · doi:10.37349/ec.2025.101264 · Cited by 7 · see citing works
HECT E3 Ubiquitin Ligase Nedd4 Is Required for Antifungal Innate Immunity
Nuro-Gyina, P. K., Tang, N., Guo, H., Yan, C., Zeng, Q., Waldschmidt, T. J., & Zhang, J. (2021) · The Journal of Immunology · doi:10.4049/jimmunol.2100083 · Cited by 5 · see citing works
Bankaitis, V. A., Tripathi, A., Chen, X., & Igumenova, T. I. (2022) · Advances in Biological Regulation · doi:10.1016/j.jbior.2022.100891 · Cited by 5 · see citing works
What Is the Target? Clinical Mycology and Diagnostics
Willinger, B. (2018) · Springer eBooks · doi:10.1007/978-3-319-92300-0_1 · Cited by 5 · see citing works
Elcocks, E., & Adukwu, E. C. (2020) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-020-04062-9 · Cited by 5 · see citing works
Ventriculoperitoneal Shunt-Associated Meningitis Caused by Candida auris: A Case Report
Chawla, R., Sud, A., Ahmad, N., & Baveja, C. P. (2018) · MAMC Journal of Medical Sciences · doi:10.4103/mamcjms.mamcjms_35_18 · Cited by 4 · see citing works
The current place of echinocandins in the treatment and prophylaxis of invasive fungal infections
Veselov, A. V. (2020) · Clinical Microbiology and Antimicrobial Chemotherapy · doi:10.36488/cmac.2020.3.197-209 · Cited by 6 · see citing works
New Bugs and New Drugs: Updates in Clinical Microbiology
Lainhart, W., Yarbrough, M. L., Jean, S., & Burnham, C. D. (2018) · The Journal of Applied Laboratory Medicine · doi:10.1373/jalm.2017.023101 · Cited by 4 · see citing works
Antifungal and molecular analysis of gene expression caused by haloperidol in Candida spp.
de Oliveira, L. C., Moreira, L. E. A., Cabral, V. P. D. F., Rodrigues, D. S., Silveira, M. J. C. B., Ferreira, J. R. D. O., de Oliveira, A. C. M., Cavalcanti, B. C., Magalhães, I. L., Ferreira, J. R. D. O., et al. (2026) · Microbial Pathogenesis · doi:10.1016/j.micpath.2026.108343 · Cited by 4 · see citing works
Mazumdar, R., & Bjelanović, A. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2026.1830629 · Cited by 3 · see citing works
Barroso, V. D. M., dos Reis, J. S., Stefani, H. A., & Ishida, K. (2024) · The Microbe · doi:10.1016/j.microb.2024.100062 · Cited by 3 · see citing works
- Authors
- Sears, D., & Schwartz, B. S.
- Affiliations
- University of California, San Francisco (US)
- Corresponding author
- Sears, David
- Venue
- International Journal of Infectious Diseases
- Publisher
- Elsevier BV
- Published
- 2017-10
- Volume
- 63
- Pages
- 95-98
- ISSN
- 1201-9712 (ISSN-L)
- OpenAlex
- W2752772336
- Cited by
- 146
- References
- 36
- Citations by year
- 2026: 8 · 2025: 8 · 2024: 10 · 2023: 7 · 2022: 18 · 2021: 16 · 2020: 26 · 2019: 30 · 2018: 22 · 2017: 1
- FWCI
- 3.31
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Journal of Infectious Diseases (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- eScholarship (California Digital Library) (submittedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Yeasts and Rust Fungi Studies
- Health Sciences › Medicine › Epidemiology › Fungal Infections and Studies
- Keywords
- Candida auris, multidrug resistance, invasive fungal infections, echinocandins, antifungal susceptibility, hospital outbreak, infection control, nosocomial infections, emerging fungal pathogens
- MeSH terms
- Antifungal Agents, Candida, Candidiasis, Cross Infection, Dose-Response Relationship, Drug, Humans, Microbial Sensitivity Tests, Infection Control, Communicable Diseases, Emerging, Drug Resistance, Multiple, Fungal, Echinocandins
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