Cited by 126Cardiac Health and Mental HealthMental Health Treatment and AccessTreatment of Major Depression

Psychopharmacology and Cardiovascular Disease

Open access
Piña, Ileana L., Di Palo, Katherine E., Ventura, Hector O.·2018·Journal of the American College of Cardiology

Abstract

This review discusses common mental health disorders and their associations with cardiovascular disease risks. Commonly found mental health disorders include depression, anxiety, and personality types. The link between depression and cardiovascular disease mortality has been established. Depression is also common in patients with heart failure. In addition to discussing psychological disorders, a review of psychotropic drugs is also included. Drugs are described for therapy for depression and anxiety, as well as associations with cardiovascular drug-drug interactions. Drug-drug interactions are more common and potentially dangerous in elderly patients, in whom the conditions often coexist. The most common drug-drug interactions involve the P450 system of enzymes.

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Crossref · 10.1016/j.jacc.2018.03.458

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  • Pharmacotherapy treatment for mental health disorders can present cardiovascular risk due to side effects of the drugs or interactions with other medications.

    “Pharmacotherapy treatment for mental health disorders can present cardiovascular risk due to side effects of the drugs or interactions with other medications (Pina 2018).”

    From Psychotherapeutic treatments for depression in older adults (2024) · cites this paper as Pina 2018

  • Pharmacological treatment of depression in patients with CVD has small effects and may be burdensome and increase the risk of side effects.

    “Pharmacological treatment of depression may be an option in patients with CVD, but the effects are small [1]. Moreover, such treatment poses a challenge as adding another medication to the existing complex medical treatment may be perceived as burdensome and might increase the risk of developing side effects [3].”

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2 of the 131 references couldn’t be matched to a known paper.

Research works printed but not linked: 2

  1. Krantz DS, Kop WJ, Santiago HT, Gottdiener JS. Mental stress as a trigger of myocardial ischemia and infarction. Cardiology clinics 1996;14(2):271-87.
  2. Ashton H. Guidelines for the rational use of benzodiazepines. Drugs 1994;48:25-40.

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Authors
Piña, I. L., Di Palo, K. E., & Ventura, H. O.
Affiliations
Albert Einstein College of Medicine (US)
Corresponding author
Piña, Ileana L.
Venue
Journal of the American College of Cardiology
Publisher
Elsevier BV
Published
2018-05
Volume
71
Issue
20
Pages
2346-2359
ISSN
0735-1097 (ISSN-L)
OpenAlex
W2803606348
Cited by
126
References
131
Citations by year
2026: 9 · 2025: 14 · 2024: 20 · 2023: 20 · 2022: 23 · 2021: 13 · 2020: 11 · 2019: 11 · 2018: 5
FWCI
1.87
Type
journal article
Language
en
Open access
Locations
  • Journal of the American College of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
  • Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
Keywords
psychopharmacology, cardiovascular disease, depression, anxiety, personality types, heart failure, cardiovascular mortality, psychotropic drugs, drug-drug interactions, elderly patients, cytochrome P450
MeSH terms
Mental Disorders, Cardiovascular Agents, Cardiovascular Diseases, Drug Interactions, Humans, Psychopharmacology, Psychotropic Drugs, Risk Factors

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