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The role of monocyte chemoattractant protein MCP1/CCL2 in neuroinflammatory diseases

Conductier, Grégory, Blondeau, Nicolas, Guyon, Alice, Nahon, Jean-Louis, Rovère, Carole·2010·Journal of Neuroimmunology
DOI 10.1016/j.jneuroim.2010.05.010
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Research works printed but not linked: 91

  1. Ajami, 2007, Local self-renewal can sustain CNS microglia maintenance and function throughout adult life, Nat. Neurosci., 10, 1538, 10.1038/nn2014 · DOI · Paper page
  2. Andjelkovic, 2000, Characterization of binding sites for chemokines MCP-1 and MIP-1alpha on human brain microvessels, J. Neurochem., 75, 1898, 10.1046/j.1471-4159.2000.0751898.x · DOI
  3. Andjelkovic, 2002, Functional expression of CCR2 by human fetal astrocytes, J. Neurosci. Res., 70, 219, 10.1002/jnr.10372 · DOI
  4. Bacon, 2002, Chemokine/chemokine receptor nomenclature, J. Interferon Cytokine Res., 22, 1067, 10.1089/107999002760624305 · DOI · Paper page
  5. Bajetto, 2001, Chemokines and their receptors in the central nervous system, Front. Neuroendocrinol., 22, 147, 10.1006/frne.2001.0214 · DOI · Paper page
  6. Banisadr, 2005, Highly regionalized neuronal expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) in rat brain: evidence for its colocalization with neurotransmitters and neuropeptides, J. Comp. Neurol., 489, 275, 10.1002/cne.20598 · DOI · Paper page
  7. Banisadr, 2005, Constitutive neuronal expression of CCR2 chemokine receptor and its colocalization with neurotransmitters in normal rat brain: functional effect of MCP-1/CCL2 on calcium mobilization in primary cultured neurons, J. Comp. Neurol., 492, 178, 10.1002/cne.20729 · DOI
  8. Barna, 1994, Regulation of monocyte chemoattractant protein-1 expression in adult human non-neoplastic astrocytes is sensitive to tumor necrosis factor (TNF) or antibody to the 55-kDa TNF receptor, J. Neuroimmunol., 50, 101, 10.1016/0165-5728(94)90220-8 · DOI
  9. Berman, 1996, Localization of monocyte chemoattractant peptide-1 expression in the central nervous system in experimental autoimmune encephalomyelitis and trauma in the rat, J. Immunol., 156, 3017, 10.4049/jimmunol.156.8.3017 · DOI · Paper page
  10. Blasko, 2006, Measurement of thirteen biological markers in CSF of patients with Alzheimer's disease and other dementias, Dement. Geriatr. Cogn. Disord., 21, 9, 10.1159/000089137 · DOI · Paper page
  11. Boddeke, 1999, Cultured rat microglia express functional beta-chemokine receptors, J. Neuroimmunol., 98, 176, 10.1016/S0165-5728(99)00096-X · DOI
  12. Bolin, 1998, Primary sensory neurons migrate in response to the chemokine RANTES, J. Neuroimmunol., 81, 49, 10.1016/S0165-5728(97)00158-6 · DOI
  13. Boring, 1997, Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C–C chemokine receptor 2 knockout mice, J. Clin. Investig., 100, 2552, 10.1172/JCI119798 · DOI · Paper page
  14. Brosnan, 1996, Mechanisms of immune injury in multiple sclerosis, Brain Pathol., 6, 243, 10.1111/j.1750-3639.1996.tb00853.x · DOI · Paper page
  15. Callewaere, 2007, Chemokines and chemokine receptors in the brain: implication in neuroendocrine regulation, J. Mol. Endocrinol., 38, 355, 10.1677/JME-06-0035 · DOI
  16. Charo, 1994, Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails, Proc. Natl Acad. Sci. USA, 91, 2752, 10.1073/pnas.91.7.2752 · DOI · Paper page
  17. Che, 2001, Monocyte chemoattractant protein-1 expressed in neurons and astrocytes during focal ischemia in mice, Brain Res., 902, 171, 10.1016/S0006-8993(01)02328-9 · DOI · Paper page
  18. Chen, 2003, Differential chemokine and chemokine receptor gene induction by ischemia, alloantigen, and gene transfer in cardiac grafts, Am. J. Transplant., 3, 1216, 10.1046/j.1600-6143.2003.00207.x · DOI
  19. Combarros, 2004, No evidence for association of the monocyte chemoattractant protein-1 (−2518) gene polymorphism and Alzheimer's disease, Neurosci. Lett., 360, 25, 10.1016/j.neulet.2004.01.035 · DOI
  20. Deshmane, 2009, Monocyte chemoattractant protein-1 (MCP-1): an overview, J. Interferon Cytokine Res., 29, 313, 10.1089/jir.2008.0027 · DOI · Paper page
  21. Diedrich, 1991, Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes, J. Virol., 65, 4759, 10.1128/jvi.65.9.4759-4768.1991 · DOI · Paper page
  22. Dirnagl, 1999, Pathobiology of ischaemic stroke: an integrated view, Trends Neurosci., 22, 391, 10.1016/S0166-2236(99)01401-0 · DOI · Paper page
  23. Eglitis, 1997, Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice, Proc. Natl Acad. Sci. USA, 94, 4080, 10.1073/pnas.94.8.4080 · DOI · Paper page
  24. Fenoglio, 2004, MCP-1 in Alzheimer's disease patients: A-2518G polymorphism and serum levels, Neurobiol. Aging, 25, 1169, 10.1016/j.neurobiolaging.2003.11.008 · DOI
  25. Fiala, 1998, Amyloid-beta induces chemokine secretion and monocyte migration across a human blood-brain barrier model, Mol. Med., 4, 480, 10.1007/BF03401753 · DOI · Paper page
  26. Floridi, 2003, Signalling pathways involved in the chemotactic activity of CXCL12 in cultured rat cerebellar neurons and CHP100 neuroepithelioma cells, J. Neuroimmunol., 135, 38, 10.1016/S0165-5728(02)00432-0 · DOI
  27. Fuentes, 1995, Controlled recruitment of monocytes and macrophages to specific organs through transgenic expression of monocyte chemoattractant protein-1, J. Immunol., 155, 5769, 10.4049/jimmunol.155.12.5769 · DOI · Paper page
  28. Galimberti, 2004, CCR2-64I polymorphism and CCR5Delta32 deletion in patients with Alzheimer's disease, J. Neurol. Sci., 225, 79, 10.1016/j.jns.2004.07.005 · DOI
  29. Gerard, 2001, Chemokines and disease, Nat. Immunol., 2, 108, 10.1038/84209 · DOI · Paper page
  30. Glabinski, 1995, Central nervous system chemokine mRNA accumulation follows initial leukocyte entry at the onset of acute murine experimental autoimmune encephalomyelitis, Brain Behav. Immun., 9, 315, 10.1006/brbi.1995.1030 · DOI · Paper page
  31. Glabinski, 1996, Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain, J. Immunol., 156, 4363, 10.4049/jimmunol.156.11.4363 · DOI · Paper page
  32. Glabinski, 1997, Synchronous synthesis of alpha- and beta-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic experimental autoimmune encephalomyelitis, Am. J. Pathol., 150, 617
  33. Glabinski, 1997, Murine experimental autoimmune encephalomyelitis: a model of immune-mediated inflammation and multiple sclerosis, Meth. Enzymol., 288, 182, 10.1016/S0076-6879(97)88015-9 · DOI
  34. Godiska, 1995, Chemokine expression in murine experimental allergic encephalomyelitis, J. Neuroimmunol., 58, 167, 10.1016/0165-5728(95)00008-P · DOI · Paper page
  35. Gong, 1997, An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model, J. Exp. Med., 186, 131, 10.1084/jem.186.1.131 · DOI · Paper page
  36. Gourmala, 1997, Differential and time-dependent expression of monocyte chemoattractant protein-1 mRNA by astrocytes and macrophages in rat brain: effects of ischemia and peripheral lipopolysaccharide administration, J. Neuroimmunol., 74, 35, 10.1016/S0165-5728(96)00203-2 · DOI
  37. Grammas, 2001, Inflammatory factors are elevated in brain microvessels in Alzheimer's disease, Neurobiol. Aging, 22, 837, 10.1016/S0197-4580(01)00276-7 · DOI · Paper page
  38. Guyon, 2009, Long term exposure to the chemokine CCL2 activates the nigrostriatal dopamine system: a novel mechanism for the control of dopamine release, Neuroscience, 162, 1072, 10.1016/j.neuroscience.2009.05.048 · DOI
  39. Handattu, 2009, Oral apolipoprotein A-I mimetic peptide improves cognitive function and reduces amyloid burden in a mouse model of Alzheimer's disease, Neurobiol. Dis., 34, 525, 10.1016/j.nbd.2009.03.007 · DOI
  40. Hanisch, 2002, Microglia as a source and target of cytokines, Glia, 40, 140, 10.1002/glia.10161 · DOI · Paper page
  41. Huang, 2005, Chronic expression of monocyte chemoattractant protein-1 in the central nervous system causes delayed encephalopathy and impaired microglial function in mice, FASEB J., 19, 761, 10.1096/fj.04-3104com · DOI
  42. Huerta, 2004, Chemokines (RANTES and MCP-1) and chemokine-receptors (CCR2 and CCR5) gene polymorphisms in Alzheimer's and Parkinson's disease, Neurosci. Lett., 370, 151, 10.1016/j.neulet.2004.08.016 · DOI
  43. Hughes, 2002, Monocyte chemoattractant protein-1 deficiency is protective in a murine stroke model, J. Cereb. Blood Flow Metab., 22, 308, 10.1097/00004647-200203000-00008 · DOI · Paper page
  44. Hulkower, 1993, Expression of CSF-1, c-fms, and MCP-1 in the central nervous system of rats with experimental allergic encephalomyelitis, J. Immunol., 150, 2525, 10.4049/jimmunol.150.6.2525 · DOI · Paper page
  45. Hurwitz, 1995, Tumor necrosis factor alpha and transforming growth factor beta upregulate astrocyte expression of monocyte chemoattractant protein-1, J. Neuroimmunol., 57, 193, 10.1016/0165-5728(95)00011-P · DOI
  46. Iarlori, 2005, Expression and production of two selected beta-chemokines in peripheral blood mononuclear cells from patients with Alzheimer's disease, Exp. Gerontol., 40, 605, 10.1016/j.exger.2005.04.007 · DOI
  47. Ishizuka, 1997, Identification of monocyte chemoattractant protein-1 in senile plaques and reactive microglia of Alzheimer's disease, Psychiatry Clin. Neurosci., 51, 135, 10.1111/j.1440-1819.1997.tb02375.x · DOI · Paper page
  48. Izikson, 2000, Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2, J. Exp. Med., 192, 1075, 10.1084/jem.192.7.1075 · DOI · Paper page
  49. Johnstone, 1999, A central role for astrocytes in the inflammatory response to beta-amyloid; chemokines, cytokines and reactive oxygen species are produced, J. Neuroimmunol., 93, 182, 10.1016/S0165-5728(98)00226-4 · DOI · Paper page
  50. Karpus, 1997, MIP-1alpha and MCP-1 differentially regulate acute and relapsing autoimmune encephalomyelitis as well as Th1/Th2 lymphocyte differentiation, J. Leukoc. Biol., 62, 681, 10.1002/jlb.62.5.681 · DOI · Paper page
  51. Kim, 1995, Expression of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 after focal cerebral ischemia in the rat, J. Neuroimmunol., 56, 127, 10.1016/0165-5728(94)00138-E · DOI · Paper page
  52. Kumai, 2004, Anti-monocyte chemoattractant protein-1 gene therapy protects against focal brain ischemia in hypertensive rats, J. Cereb. Blood Flow Metab., 24, 1359, 10.1097/01.WCB.0000143534.76388.3C · DOI
  53. Kurihara, 1997, Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor, J. Exp. Med., 186, 1757, 10.1084/jem.186.10.1757 · DOI · Paper page
  54. Lu, 2003, Targeting PI3K-AKT pathway for cancer therapy, Rev. Clin. Exp. Hematol., 7, 205
  55. Lucas, 2006, The role of inflammation in CNS injury and disease, Br. J. Pharmacol., 147, S232
  56. Lucchinetti, 1996, Distinct patterns of multiple sclerosis pathology indicates heterogeneity on pathogenesis, Brain Pathol., 6, 259, 10.1111/j.1750-3639.1996.tb00854.x · DOI · Paper page
  57. Lue, 2001, Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro, Glia, 35, 72, 10.1002/glia.1072 · DOI · Paper page
  58. McManus, 1998, MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: an immunohistochemical and in situ hybridization study, J. Neuroimmunol., 86, 20, 10.1016/S0165-5728(98)00002-2 · DOI · Paper page
  59. Mehlhorn, 2000, Induction of cytokines in glial cells surrounding cortical beta-amyloid plaques in transgenic Tg2576 mice with Alzheimer pathology, Int. J. Dev. Neurosci., 18, 423, 10.1016/S0736-5748(00)00012-5 · DOI · Paper page
  60. Murphy, 2002, International Union of Pharmacology. XXX. Update on chemokine receptor nomenclature, Pharmacol. Rev., 54, 227, 10.1124/pr.54.2.227 · DOI · Paper page
  61. Nakajima, 2007, Increased intrathecal chemokine receptor CCR2 expression in multiple sclerosis, Biomarker Insights, 2, 463, 10.1177/117727190700200028 · DOI
  62. Plata-Salaman, 1994, Chemokines/intercrines and central regulation of feeding, Am. J. Physiol., 266, R1711
  63. Pola, 2004, Monocyte chemoattractant protein-1 (MCP-1) gene polymorphism and risk of Alzheimer's disease in Italians, Exp. Gerontol., 39, 1249, 10.1016/j.exger.2004.05.001 · DOI
  64. Popescu, 2009, Blood-brain barrier alterations in ageing and dementia, J. Neurol. Sci., 283, 99, 10.1016/j.jns.2009.02.321 · DOI
  65. Ransohoff, 2002, The chemokine system in neuroinflammation: an update, J. Infect. Dis., 186, S152, 10.1086/344266 · DOI
  66. Reale, 2006, The acetylcholinesterase inhibitor, donepezil, regulates a Th2 bias in Alzheimer's disease patients, Neuropharmacology, 50, 606, 10.1016/j.neuropharm.2005.11.006 · DOI
  67. Reale, 2008, Peripheral chemokine receptors, their ligands, cytokines and Alzheimer's disease, J. Alzheimers Dis., 14, 147, 10.3233/JAD-2008-14203 · DOI
  68. Reyes, 2003, Categorically distinct acute stressors elicit dissimilar transcriptional profiles in the paraventricular nucleus of the hypothalamus, J. Neurosci., 23, 5607, 10.1523/JNEUROSCI.23-13-05607.2003 · DOI
  69. Rollins, 1996, Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease, Mol. Med. Today, 2, 198, 10.1016/1357-4310(96)88772-7 · DOI · Paper page
  70. Rostène, 2007, Chemokines: a new class of neuromodulator?, Nat. Rev. Neurosci., 8, 895, 10.1038/nrn2255 · DOI · Paper page
  71. Rovin, 1999, A novel polymorphism in the MCP-1 gene regulatory region that influences MCP-1 expression, Biochem. Biophys. Res. Commun., 259, 344, 10.1006/bbrc.1999.0796 · DOI · Paper page
  72. Ruan, 2009, Amyloid deposition and inflammation in APPswe/PS1dE9 mouse model of Alzheimer's disease, Curr. Alzheimer Res., 6, 531, 10.2174/156720509790147070 · DOI · Paper page
  73. Schimmer, 1998, Streptococcal cell wall-induced arthritis: requirements for IL-4, IL-10, IFN-gamma, and monocyte chemoattractant protein-1, J. Immunol., 160, 1466, 10.4049/jimmunol.160.3.1466 · doi:10.4049/jimmunol.160.3.1466
  74. Schlachetzki, 2009, Microglial activation in Alzheimer's disease, Curr. Alzheimer Res., 6, 554, 10.2174/156720509790147179 · DOI
  75. Semple, 2010, Role of chemokines in CNS health and pathology: a focus on the CCL2/CCR2 and CXCL8/CXCR2 networks, J. Cereb. Blood Flow Metab., 30, 459, 10.1038/jcbfm.2009.240 · DOI · Paper page
  76. Simard, 2006, Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease, Neuron, 49, 489, 10.1016/j.neuron.2006.01.022 · DOI · Paper page
  77. Simpson, 1998, Expression of monocyte chemoattractant protein-1 and other beta-chemokines by resident glia and inflammatory cells in multiple sclerosis lesions, J. Neuroimmunol., 84, 238, 10.1016/S0165-5728(97)00208-7 · DOI · Paper page
  78. Simpson, 2000, Expression of the beta-chemokine receptors CCR2, CCR3 and CCR5 in multiple sclerosis central nervous system tissue, J. Neuroimmunol., 108, 192, 10.1016/S0165-5728(00)00274-5 · DOI · Paper page
  79. Smits, 2002, Amyloid-beta-induced chemokine production in primary human macrophages and astrocytes, J. Neuroimmunol., 127, 160, 10.1016/S0165-5728(02)00112-1 · DOI
  80. Sorensen, 2004, Chemokine CCL2 and chemokine receptor CCR2 in early active multiple sclerosis, Eur. J. Neurol., 11, 445, 10.1111/j.1468-1331.2004.00796.x · DOI
  81. Sozzani, 1994, Receptors and transduction pathways for monocyte chemotactic protein-2 and monocyte chemotactic protein-3. Similarities and differences with MCP-1, J. Immunol., 152, 3615, 10.4049/jimmunol.152.7.3615 · DOI · Paper page
  82. Sun, 2003, Inflammatory markers in matched plasma and cerebrospinal fluid from patients with Alzheimer's disease, Dement. Geriatr. Cogn. Disord., 16, 136, 10.1159/000071001 · DOI · Paper page
  83. Szczepanik, 2001, IL-4, IL-10 and IL-13 modulate A beta(1-42)-induced cytokine and chemokine production in primary murine microglia and a human monocyte cell line, J. Neuroimmunol., 113, 49, 10.1016/S0165-5728(00)00404-5 · DOI
  84. Thelen, 2001, Dancing to the tune of chemokines, Nat. Immunol., 2, 129, 10.1038/84224 · DOI · Paper page
  85. Thibeault, 2001, Regulation of the gene encoding the monocyte chemoattractant protein 1 (MCP-1) in the mouse and rat brain in response to circulating LPS and proinflammatory cytokines, J. Comp. Neurol., 434, 461, 10.1002/cne.1187 · DOI
  86. Thompson, 2009, Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-7 through NFkappaB and MAPK dependent pathways in rat astrocytes, Brain Res., 1287, 47, 10.1016/j.brainres.2009.06.081 · DOI · Paper page
  87. Tran, 2004, Chemokine receptors are expressed widely by embryonic and adult neural progenitor cells, J. Neurosci. Res., 76, 20, 10.1002/jnr.20001 · DOI · Paper page
  88. Van Coillie, 1999, The MCP/eotaxin subfamily of CC chemokines, Cytokine Growth Factor Rev., 10, 61, 10.1016/S1359-6101(99)00005-2 · DOI · Paper page
  89. Wain, 2002, Leucocyte chemotaxis: Examination of mitogen-activated protein kinase and phosphoinositide 3-kinase activation by monocyte chemoattractant proteins-1, -2, -3 and-4, Clin. Exp. Immunol., 127, 436, 10.1046/j.1365-2249.2002.01764.x · DOI
  90. Wang, 1995, Induced expression of adhesion molecules following focal brain ischemia, J. Neurotrauma, 12, 825, 10.1089/neu.1995.12.825 · DOI
  91. Xia, 2009, Recent developments in CCR2 antagonists, Expert Opin. Ther. Pat., 19, 295, 10.1517/13543770902755129 · DOI · Paper page

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Metadata

Authors
Conductier, G., Blondeau, N., Guyon, A., Nahon, J.-L., & Rovère, C.
Venue
Journal of Neuroimmunology
Publisher
Elsevier BV
Published
2010-07
Volume
224
Issue
1-2
Pages
93-100
ISSN
0165-5728 (ISSN-L)
DOI
10.1016/j.jneuroim.2010.05.010
OpenAlex
W2007618030
Cited by
404
References
14
FWCI
15.32
Type
journal article
Language
en
Open access
closed
Licence
  • www.elsevier.com/tdm/userlicense/1.0/ (tdm)
  • www.elsevier.com/legal/tdmrep-license (tdm)

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Conductier, G., Blondeau, N., Guyon, A., Nahon, J.-L., & Rovère, C. (2010). The role of monocyte chemoattractant protein MCP1/CCL2 in neuroinflammatory diseases. Journal of Neuroimmunology. https://doi.org/10.1016/j.jneuroim.2010.05.010

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