Adiponectin and energy homeostasis: consensus and controversy

Dridi, Sami; Taouis, Mohammed

doi:10.1016/j.jnutbio.2009.06.003

Cited by 85Adipokines, Inflammation, and Metabolic DiseasesRegulation of Appetite and ObesityAdipose Tissue and Metabolism

Adiponectin and energy homeostasis: consensus and controversy

Dridi, Sami, Taouis, Mohammed·2009·The Journal of Nutritional Biochemistry

DOI 10.1016/j.jnutbio.2009.06.003

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Abstract

Adiponectin regulates energy homeostasis through the modulation of glucose and fatty acid metabolism in peripheral tissues. However, its central effect on energy balance remains unclear and controversial. Despite the disparate data, recent advances in our understanding of the signal transduction mechanisms used by adiponectin in the periphery and in the hypothalamus suggest that intracellular cross-talk between adiponectin, leptin and insulin may occur at several levels. The present review will summarize recent reports describing the peripheral and central effects of adiponectin and discuss progress concerning its molecular mechanisms. We will also particularly focus on apparent controversies and related mechanisms associated with the central effects of adiponectin on energy homeostasis.

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The role of adiponectin in energy homeostasis is unclear: increases, decreases, or no changes in energy balance are derived from peripheral adiponectin administration in rodents.
“Its role in energy homeostasis is unclear: increases, decreases, or no changes in energy balance are derived from peripheral adiponectin administration in rodents.62”
From Interacting epidemics? Sleep curtailment, insulin resistance, and obesity (2012) · cites this paper as [62]

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
Yamauchi, T., Kamon, J., Waki, H., Terauchi, Y., Kubota, N., Hara, K., Mori, Y., Ide, T., Murakami, K., Tsuboyama-Kasaoka, N., et al. (2001) · Nature Medicine · doi:10.1038/90984 · Cited by 4,915 · see citing works
Obesity as a medical problem
Kopelman, P. G. (2000) · Nature · doi:10.1038/35007508 · Cited by 4,795 · see citing works
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
Yamauchi, T., Kamon, J., Minokoshi, Y., Ito, Y., Waki, H., Uchida, S., Yamashita, S., Noda, M., Kita, S., Ueki, K., et al. (2002) · Nature Medicine · doi:10.1038/nm788 · Cited by 4,238 · see citing works
A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes
Scherer, P. E., Williams, S. P., Fogliano, M., Baldini, G., & Lodish, H. F. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.45.26746 · Cited by 3,238 · see citing works
Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
Yamauchi, T., Kamon, J., Ito, Y., Tsuchida, A., Yokomizo, T., Kita, S., Sugiyama, T., Miyagishi, M., Hara, K., Tsunoda, M., et al. (2003) · Nature · doi:10.1038/nature01705 · Cited by 3,176 · see citing works
Excess Deaths Associated With Underweight, Overweight, and Obesity
Flegal, K. M. (2005) · JAMA · doi:10.1001/jama.293.15.1861 · Cited by 2,834 · see citing works
The Continuing Epidemics of Obesity and Diabetes in the United States
Mokdad, A. H. (2001) · JAMA · doi:10.1001/jama.286.10.1195 · Cited by 2,730 · see citing works
Adiponectin and Adiponectin Receptors
Kadowaki, T., & Yamauchi, T. (2005) · Endocrine Reviews · doi:10.1210/er.2005-0005 · Cited by 2,634 · see citing works
The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
Berg, A. H., Combs, T. P., Du, X., Brownlee, M., & Scherer, P. E. (2001) · Nature Medicine · doi:10.1038/90992 · Cited by 2,526 · see citing works
AdipoQ Is a Novel Adipose-specific Gene Dysregulated in Obesity
Hu, E., Liang, P., & Spiegelman, B. M. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.18.10697 · Cited by 2,239 · see citing works
Adipokines: inflammation and the pleiotropic role of white adipose tissue
Trayhurn, P., & Wood, I. S. (2004) · British Journal of Nutrition · doi:10.1079/bjn20041213 · Cited by 2,210 · see citing works
cDNA Cloning and Expression of a Novel Adipose Specific Collagen-like Factor, apM1 (AdiposeMost Abundant Gene Transcript 1)
Maeda, K., Okubo, K., Shimomura, I., Funahashi, T., Matsuzawa, Y., & Matsubara, K. (1996) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1996.0587 · Cited by 2,081 · see citing works
Diet-induced insulin resistance in mice lacking adiponectin/ACRP30
Maeda, N., Shimomura, I., Kishida, K., Nishizawa, H., Matsuda, M., Nagaretani, H., Furuyama, N., Kondo, H., Takahashi, M., Arita, Y., et al. (2002) · Nature Medicine · doi:10.1038/nm724 · Cited by 2,074 · see citing works
Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice
Fruebis, J., Tsao, T., Javorschi, S., Ebbets-Reed, D., Erickson, M., Yen, F. T., Bihain, B. E., & Lodish, H. F. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.4.2005 · Cited by 1,987 · see citing works
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
Minokoshi, Y., Alquier, T., Furukawa, N., Kim, Y.-B., Lee, A., Xue, B., Mu, J., Foufelle, F., Ferré, P., Birnbaum, M. J., et al. (2004) · Nature · doi:10.1038/nature02440 · Cited by 1,637 · see citing works
Adipose Tissue as an Endocrine Organ
Ahima, R. S., & Flier, J. S. (2000) · Trends in Endocrinology & Metabolism · doi:10.1016/s1043-2760(00)00301-5 · Cited by 1,608 · see citing works
Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions
Yamauchi, T., Nio, Y., Maki, T., Kobayashi, M., Takazawa, T., Iwabu, M., Okada-Iwabu, M., Kawamoto, S., Kubota, N., Kubota, T., et al. (2007) · Nature Medicine · doi:10.1038/nm1557 · Cited by 1,396 · see citing works
Disruption of Adiponectin Causes Insulin Resistance and Neointimal Formation
Kubota, N., Terauchi, Y., Yamauchi, T., Kubota, T., Moroi, M., Matsui, J., Eto, K., Yamashita, T., Kamon, J., Satoh, H., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.c200251200 · Cited by 1,213 · see citing works
ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism
Berg, A. H., Combs, T. P., & Scherer, P. E. (2002) · Trends in Endocrinology and Metabolism · doi:10.1016/s1043-2760(01)00524-0 · Cited by 1,211 · see citing works
Disruption of adiponectin causes insulin resistance and neointimal formation
Froguel, P. (2002) · HAL · Cited by 1,126 · see citing works
Structure-Function Studies of the Adipocyte-secreted Hormone Acrp30/Adiponectin
Pajvani, U. B., Du, X., Combs, T. P., Berg, A. H., Rajala, M. W., Schulthess, T., Engel, J., Brownlee, M., & Scherer, P. E. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m207198200 · Cited by 1,090 · see citing works
Adipose tissue as an endocrine and paracrine organ
Mohamed‐Ali, V., Pinkney, J. H., & Coppack, S. W. (1998) · International Journal of Obesity · doi:10.1038/sj.ijo.0800770 · Cited by 999 · see citing works
Impaired Multimerization of Human Adiponectin Mutants Associated with Diabetes
Waki, H., Yamauchi, T., Kamon, J., Ito, Y., Uchida, S., Kita, S., Hara, K., Hada, Y., Vasseur, F., Froguel, P., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300365200 · Cited by 981 · see citing works
Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation
Tomas, E., Tsao, T.-S., Saha, A. K., Murrey, H. E., Zhang, C. C., Itani, S. I., Lodish, H. F., & Ruderman, N. B. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.222657499 · Cited by 973 · see citing works
Isolation and Characterization of GBP28, a Novel Gelatin-Binding Protein Purified from Human Plasma
Nakano, Y., Tobe, T., Choi-Miura, N.-H., Mazda, T., & Tomita, M. (1996) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a021483 · Cited by 915 · see citing works
Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis
Yamauchi, T., Kamon, J., Waki, H., Imai, Y., Shimozawa, N., Hioki, K., Uchida, S., Ito, Y., Takakuwa, K., Matsui, J., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m209033200 · Cited by 911 · see citing works
T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin
Hug, C., Wang, J., Ahmad, N. S., Bogan, J. S., Tsao, T., & Lodish, H. F. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403382101 · Cited by 861 · see citing works
Adiponectin Stimulates AMP-Activated Protein Kinase in the Hypothalamus and Increases Food Intake
Kubota, N., Yano, W., Kubota, T., Yamauchi, T., Itoh, S., Kumagai, H., Kozono, H., Takamoto, I., Okamoto, S., Shiuchi, T., et al. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.06.003 · Cited by 844 · see citing works
Adiponectin acts in the brain to decrease body weight
Qi, Y., Takahashi, N., Hileman, S. M., Patel, H. R., Berg, A. H., Pajvani, U. B., Scherer, P. E., & Ahima, R. S. (2004) · Nature Medicine · doi:10.1038/nm1029 · Cited by 809 · see citing works
AMP-activated Protein Kinase Plays a Role in the Control of Food Intake
Andersson-Hall, U. K., Filipsson, K., Abbott, C. R., Woods, A., Smith, K. L., Bloom, S. R., Carling, D., & Small, C. J. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.c300557200 · Cited by 755 · see citing works
Cytokine Stimulation of Energy Expenditure through p38 MAP Kinase Activation of PPARγ Coactivator-1
Puigserver, P., Rhee, J., Lin, J., Wu, Z., Yoon, J. C., Zhang, C.-Y., Krauss, S., Mootha, V. K., Lowell, B. B., & Spiegelman, B. M. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00390-2 · Cited by 732 · cited 1× · see citing works
“It has been shown that p38MAPK phosphorylate and activate PPAR and its co-activator peroxisome proliferator-activated receptor gamma coactivator 1α [39].”
Background
Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation
Fu, Y., Luo, N., Klein, R. L., & Garvey, W. T. (2005) · Journal of Lipid Research · doi:10.1194/jlr.m400373-jlr200 · Cited by 666 · see citing works
APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function
Mao, X., Kikani, C. K., Riojas, R. A., Langlais, P. R., Wang, L., Ramos, F. J., Fang, Q., Christ-Roberts, C. Y., Hong, J., Kim, R. Y., et al. (2006) · Nature Cell Biology · doi:10.1038/ncb1404 · Cited by 661 · see citing works
Mice Lacking Adiponectin Show Decreased Hepatic Insulin Sensitivity and Reduced Responsiveness to Peroxisome Proliferator-activated Receptor γ Agonists
Nawrocki, A. R., Rajala, M. W., Tomás, E., Pajvani, U. B., Saha, A. K., Trumbauer, M. E., Pang, Z., Chen, A. S., Ruderman, N. B., Chen, H., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m505311200 · Cited by 640 · see citing works
Adiponectin Increases Fatty Acid Oxidation in Skeletal Muscle Cells by Sequential Activation of AMP-Activated Protein Kinase, p38 Mitogen-Activated Protein Kinase, and Peroxisome Proliferator–Activated Receptor α
Yoon, M. J., Lee, G. Y., Chung, J.-J., Ahn, Y. H., Hong, S. H., & Kim, J. B. (2006) · Diabetes · doi:10.2337/db05-1322 · Cited by 546 · see citing works
Involvement of AMP-activated protein kinase in glucose uptake stimulated by the globular domain of adiponectin in primary rat adipocytes.
Wu, X.-D., Motoshima, H., Mahadev, K., Stalker, T. J., Scalia, R., & Goldstein, B. (2003) · Diabetes · doi:10.2337/diabetes.52.6.1355 · Cited by 471 · see citing works
A family of Acrp30/adiponectin structural and functional paralogs
Wong, G. W., Wang, J., Hug, C., Tsao, T., & Lodish, H. F. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403760101 · Cited by 419 · see citing works
The TRH neuron: a hypothalamic integrator of energy metabolism
Lechan, R. M., & Fekete, C. (2006) · Progress in brain research · doi:10.1016/s0079-6123(06)53012-2 · Cited by 338 · see citing works
Role of adipose tissue in body-weight regulation: mechanisms regulating leptin production and energy balance
Havel, P. J. (2000) · Proceedings of The Nutrition Society · doi:10.1017/s0029665100000410 · Cited by 329 · see citing works
Pioglitazone Ameliorates Insulin Resistance and Diabetes by Both Adiponectin-dependent and -independent Pathways
Kubota, N., Terauchi, Y., Kubota, T., Kumagai, H., Itoh, S., Satoh, H., Yano, W., Ogata, H., Tokuyama, K., Takamoto, I., et al. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m505649200 · Cited by 327 · see citing works
Generation of globular fragment of adiponectin by leukocyte elastase secreted by monocytic cell line THP-1
Waki, H., Yamauchi, T., Kamon, J., Kita, S., Ito, Y., Hada, Y., Uchida, S., Tsuchida, A., Takekawa, S., & Kadowaki, T. (2005) · Endocrinology · doi:10.1210/en.2004-1096 · Cited by 319 · see citing works
Opposing Effects of Adiponectin Receptors 1 and 2 on Energy Metabolism
Bjursell, M., Ahnmark, A., Bohlooly‐Y, M., William‐Olsson, L., Rhedin, M., Peng, X., Ploj, K., Gerdin, A.-K., Arnerup, G., Elmgren, A., et al. (2007) · Diabetes · doi:10.2337/db06-1432 · Cited by 277 · see citing works
Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats
Shklyaev, S., Aslanidi, G., Tennant, M., Prima, V., Kohlbrenner, E., Kroutov, V., Campbell‐Thompson, M., Crawford, J. M., Shek, E. W., Scarpace, P. J., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2333912100 · Cited by 244 · see citing works
Adiponectin and Resistin in Human Cerebrospinal Fluid and Expression of Adiponectin Receptors in the Human Hypothalamus
Kos, K., Harte, A. L., da Silva, N. F., Tonchev, A. B., Chaldakov, G., James, S. G., Snead, D. R. J., Hoggart, B., O’Hare, J. P., McTernan, P. G., et al. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-1841 · Cited by 234 · see citing works
Differential BBB interactions of three ingestive peptides: obestatin, ghrelin, and adiponectin.
Pan, W., Tu, H., & Kastin, A. (2006) · Peptides · doi:10.1016/j.peptides.2005.12.014 · Cited by 226 · see citing works
Adiponectin Does Not Cross the Blood-Brain Barrier but Modifies Cytokine Expression of Brain Endothelial Cells
Spranger, J., Verma, S., Göhring, I., Bobbert, T., Seifert, J., Sindler, A. L., Pfeiffer, A. F. H., Hileman, S. M., Tschöp, M. H., & Banks, W. A. (2006) · Diabetes · doi:10.2337/diabetes.55.01.06.db05-1077 · Cited by 217 · see citing works
Adiponectin Sensitizes Insulin Signaling by Reducing p70 S6 Kinase-mediated Serine Phosphorylation of IRS-1
Wang, C., Mao, X., Wang, L., Liu, M., Wetzel, M. D., Guan, K.-L., Dong, L. Q., & Liu, F. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m700098200 · Cited by 210 · see citing works
Central effects of CRF on metabolism and energy balance
Rothwell, N. J. (1990) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(05)80037-5 · Cited by 189 · see citing works
Review article: adipocytokines and insulin resistance
Vettor, R., Milan, G., Rossato, M., & Federspil, G. (2005) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2005.02587.x · Cited by 185 · see citing works
Hypothalamic obesity
Bray, G. A., Inoue, S., & Nishizawà, Y. (1981) · Diabetologia · doi:10.1007/bf00254505 · Cited by 170 · see citing works
AdipoR1 mediates the anorexigenic and insulin/leptin‐like actions of adiponectin in the hypothalamus
Coope, A., Milanski, M., ARAUJO, E. P. D., Tambascia, M. A., Saad, M. J. A., Geloneze, B., & Velloso, L. A. (2008) · FEBS Letters · doi:10.1016/j.febslet.2008.03.037 · Cited by 165 · see citing works
Adiponectin receptors are expressed in hypothalamus and colocalized with proopiomelanocortin and neuropeptide Y in rodent arcuate neurons
Guillod-Maximin, E., Roy, A.-F., Vacher, C., Aubourg, A., Bailleux, V., Lorsignol, A., Pénicaud, L., Parquet, M., & Taouis, M. (2008) · Journal of Endocrinology · doi:10.1677/joe-08-0348 · Cited by 163 · see citing works
Self-citation
Adiponectin Gene Is Expressed in Multiple Tissues in the Chicken: Food Deprivation Influences Adiponectin Messenger Ribonucleic Acid Expression
Maddineni, S. R., Metzger, S. L., Ocón, O. M., Hendricks, G. L., & Ramachandran, R. (2005) · Endocrinology · doi:10.1210/en.2005-0254 · Cited by 128 · see citing works
Adipokine Gene Expression in Brain and Pituitary Gland
Wilkinson, M., Brown, R., Imran, S. A., & Ur, E. (2007) · Neuroendocrinology · doi:10.1159/000108635 · Cited by 121 · see citing works
Adiponectin activates c-Jun NH2-terminal kinase and inhibits signal transducer and activator of transcription 3
Miyazaki, T., Bub, J. D., Uzuki, M., & Iwamoto, Y. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.05.076 · Cited by 118 · see citing works
Area Postrema Neurons Are Modulated by the Adipocyte Hormone Adiponectin
Fry, M., Smith, P. M., Hoyda, T. D., Duncan, M., Ahima, R. S., Sharkey, K. A., & Ferguson, A. V. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.2014-06.2006 · Cited by 100 · see citing works
Neurophysiology of hunger and satiety
Smith, P., & Ferguson, A. V. (2008) · Developmental Disabilities Research Reviews · doi:10.1002/ddrr.13 · Cited by 74 · see citing works
Adiponectin Depolarizes Parvocellular Paraventricular Nucleus Neurons Controlling Neuroendocrine and Autonomic Function
Hoyda, T. D., Samson, W. K., & Ferguson, A. V. (2008) · Endocrinology · doi:10.1210/en.2008-1179 · Cited by 55 · see citing works
Proteomic characterization of human serum proteins associated with the fat‐derived hormone adiponectin
Wang, Y., Xu, L. Y., Lam, K. S. L., Lü, G., Cooper, G. J. S., & Xu, A. (2006) · PROTEOMICS · doi:10.1002/pmic.200500840 · Cited by 53 · see citing works
Adiponectin protects human neuroblastoma SH-SY5Y cells against MPP+-induced cytotoxicity
Jung, T. W., Lee, J. Y., Shim, W. S., Kang, E. S., Kim, J., Ahn, C. W., Lee, H. C., & Soo, B. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.02.186 · Cited by 51 · see citing works
Corticotropin-releasing factor receptor blockade enhances conditioned aversive properties of cocaine in rats
Heinrichs, S. C., Klaassen, A., Koob, G. F., Schulteis, G., Ahmed, S. H., & Souza, E. B. D. (1998) · Psychopharmacology · doi:10.1007/s002130050563 · Cited by 28 · see citing works
ICV administration of anti-corticotropin-releasing factor antisense oligonucleotide: effects on feeding behavior and body weight
Hulsey, M. G., Pless, C. M., & Martin, R. J. (1995) · Regulatory Peptides · doi:10.1016/0167-0115(95)00109-o · Cited by 21 · see citing works
Adiponectin values are unchanged during pregnancy in rats
Caja, S., Torrente, M., Martínez, I. T. M., Abelenda, M., & Puerta, M. (2005) · Journal of Endocrinological Investigation · doi:10.1007/bf03347259 · Cited by 12 · see citing works

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Pimentel, G. D., Lira, F. S., Neto, J. C. R., Caris, A. V., Pinheiro, F., Ribeiro, E. B., do Nascimento, C. M. O., & Oyama, L. M. (2012) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2012.04.016 · Cited by 76 · see citing works
Intake of trans fatty acids during gestation and lactation leads to hypothalamic inflammation via TLR4/NFκBp65 signaling in adult offspring
Pimentel, G. D., Lira, F. S., Neto, J. C. R., de Oliveira, J. L., Hachul, A. C. L., Souza, G. I. H., do Carmo, M. D. G. T., dos Santos, R. V. T., de Mello, M. T., Tufik, S., et al. (2011) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2010.12.003 · Cited by 68 · see citing works
Phentermine, topiramate and their combination for the treatment of adiposopathy ('sick fat') and metabolic disease
Bays, H. (2010) · Expert Review of Cardiovascular Therapy · doi:10.1586/erc.10.125 · Cited by 66 · see citing works
The Adiponectin Paradox in the Elderly: Associations With Body Composition, Physical Functioning, and Mortality
Baker, J. F., Newman, A. B., Kanaya, A. M., Leonard, M. B., Zemel, B. S., Miljkovic, I., Long, J., Weber, D. R., & Harris, T. B. (2018) · The Journals of Gerontology Series A · doi:10.1093/gerona/gly017 · Cited by 65 · see citing works
Dietary glycemic index/load and peripheral adipokines and inflammatory markers in elderly subjects at high cardiovascular risk
Bulló, M., Casas, R. M., Portillo, M. P., Basora, J., Estruch, R., García‐Arellano, A., Lasa, A., Juanola‐Falgarona, M., Arós, F., & Salas‐Salvadó, J. (2011) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2011.09.009 · Cited by 64 · see citing works
Peripheral signalling involved in energy homeostasis control
Lancha, A., Frühbeck, G., & Gómez‐Ambrosi, J. (2012) · Nutrition Research Reviews · doi:10.1017/s0954422412000145 · Cited by 65 · see citing works
Combination of the sodium-glucose cotransporter-2 inhibitor empagliflozin with orlistat or sibutramine further improves the body-weight reduction and glucose homeostasis of obese rats fed a cafeteria diet
Vickers, S. P., Cheetham, S. C., Headland, K. R., Dickinson, K., Grempler, R., Mayoux, E., Mark, M., & Klein, T. (2014) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s58786 · Cited by 63 · see citing works
Cerebral insulin, insulin signaling pathway, and brain angiogenesis
Zeng, Y., Zhang, L., & Hu, Z. (2015) · Neurological Sciences · doi:10.1007/s10072-015-2386-8 · Cited by 51 · see citing works
Effect of various treatments on leptin, adiponectin, ghrelin and neuropeptide Y in patients with type 2 diabetes mellitus
Katsiki, N., Mikhailidis, D. P., Gotzamani‐Psarrakou, A., Yovos, J. G., & Karamitsos, D. T. (2011) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.2011.553609 · Cited by 50 · see citing works
Plasma Adiponectin Levels Correlate Positively with an Increasing Number of Components of Frailty in Male Elders
Tsai, J., Wu, C., Chen, S., Huang, K., Chen, C., Chang, C.-I., Chuang, L., & Chen, C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0056250 · Cited by 50 · see citing works
Glucocorticoid Effects on Adiponectin Expression
Sukumaran, S., DuBois, D. C., Jusko, W. J., & Almon, R. R. (2012) · Vitamins and hormones · doi:10.1016/b978-0-12-398313-8.00007-5 · Cited by 47 · see citing works
Effect of the diet components on adiponectin levels.
Reis, C. E. G., Bressan, J., & Alfenas, R. D. C. G. (2010) · PubMed · Cited by 40 · see citing works
Interferon beta overexpression attenuates adipose tissue inflammation and high-fat diet-induced obesity and maintains glucose homeostasis
Alsaggar, M., Mills, M. J., & Liu, D. (2016) · Gene Therapy · doi:10.1038/gt.2016.76 · Cited by 36 · see citing works
Antiobesity Effects of an Edible HalophyteNitraria retusaForssk in 3T3-L1 Preadipocyte Differentiation and in C57B6J/L Mice Fed a High Fat Diet-Induced Obesity
Kalai, F. Z., Han, J., Ksouri, R., Omri, A. E., Abdelly, C., & Isoda, H. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/368658 · Cited by 31 · see citing works
Thermogenic adipocytes: lineage, function and therapeutic potential
Pollard, A., & Carling, D. (2020) · Biochemical Journal · doi:10.1042/bcj20200298 · Cited by 29 · see citing works
Testosterone Deprivation Aggravates Left-Ventricular Dysfunction in Male Obese Insulin-Resistant Rats via Impairing Cardiac Mitochondrial Function and Dynamics Proteins
Apaiajai, N., Chunchai, T., Jaiwongkam, T., Kerdphoo, S., Chattipakorn, S. C., & Chattipakorn, N. (2018) · Gerontology · doi:10.1159/000487188 · Cited by 28 · see citing works
Adipocyte–Brain: Crosstalk
Schulz, C., Paulus, K., & Lehnert, H. (2010) · Results and problems in cell differentiation · doi:10.1007/978-3-642-14426-4_16 · Cited by 26 · see citing works
AdipoR1 and 2 are expressed on warm sensitive neurons of the hypothalamic preoptic area and contribute to central hyperthermic effects of adiponectin
Klein, I., Sánchez-Alavez, M., Tabarean, I. V., Schaefer, J. F., Holmberg, K. H., Klaus, J., Xia, F., Marcondes, M. C. G., Dubins, J. S., Morrison, B. E., et al. (2011) · Brain Research · doi:10.1016/j.brainres.2011.09.019 · Cited by 26 · see citing works
Expression profile of hypothalamic neuropeptides in chicken lines selected for high or low residual feed intake
Sintubin, P., Greene, E., Collin, A., Bordas, A., Zerjal, T., Tesseraud, S., Buyse, J. G., & Dridi, S. (2014) · Neuropeptides · doi:10.1016/j.npep.2014.04.007 · Cited by 26 · see citing works
Self-citation
Serum leptin levels are inversely correlated with omental gene expression of adiponectin and markedly decreased after gastric bypass surgery
Chen, J., Pamuklar, Z. N., Spagnoli, A., & Torquati, A. (2011) · Surgical Endoscopy · doi:10.1007/s00464-011-2059-5 · Cited by 25 · see citing works
Benefits of healthy adipose tissue in the treatment of diabetes
Gunawardana, S. C. (2014) · World Journal of Diabetes · doi:10.4239/wjd.v5.i4.420 · Cited by 24 · see citing works
Optimization of adiponectin‐derived peptides for inhibition of cancer cell growth and signaling
Otvos, L. J., Kovalszky, I., Oláh, J., Coroniti, R., Knappe, D., Nollmann, F. I., Hoffmann, R., Wade, J. D., Lovas, S., & Surmacz, E. (2015) · Biopolymers · doi:10.1002/bip.22627 · Cited by 24 · see citing works
A Quantified Ginseng (Panax ginseng C.A. Meyer) Extract Influences Lipid Acquisition and Increases Adiponectin Expression in 3T3-L1 Cells
Yeo, C.-R., Chen, Y., Wong, T.-Y., & Popovich, D. G. (2011) · Molecules · doi:10.3390/molecules16010477 · Cited by 23 · see citing works
The Role of Psychobiological and Neuroendocrine Mechanisms in Appetite Regulation and Obesity
Πασπάλα, Ι., Katsiki, N., Καπουκρανίδου, Δ., Mikhailidis, D. P., & Fachantidou, A. (2012) · The Open Cardiovascular Medicine Journal · doi:10.2174/1874192401206010147 · Cited by 24 · see citing works
Negative regulation of adiponectin secretion by receptor interacting protein 140 (RIP140)
Ho, P., & Wei, L. (2011) · Cellular Signalling · doi:10.1016/j.cellsig.2011.07.018 · Cited by 22 · see citing works
AdipoR-increased intracellular ROS promotes cPLA2and COX-2 expressions via activation of PKC and p300 in adiponectin-stimulated human alveolar type II cells
Chen, H., Yang, C., Chang, J., Wu, C., Sia, K., & Lin, W. (2016) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00218.2015 · Cited by 22 · see citing works
Effects of Improving Glycemic Control with Insulin on Leptin, Adiponectin, Ghrelin and Neuropeptidey Levels in Patients with Type 2 Diabetes Mellitus: a Pilot Study
Katsiki, N., Mikhailidis, D. P., Gotzamani-Psarrakou, A., Didangelos, T., Yovos, J. G., & Karamitsos, D. T. (2011) · The Open Cardiovascular Medicine Journal · doi:10.2174/1874192401105010136 · Cited by 20 · see citing works
Maternal and cord blood adiponectin levels in relation to post-natal body size in infants in the first year of life: a prospective study
Zhang, Z.-Q., Lu, Q., Huang, J., Jiao, C., Huang, S., & Mao, L. (2016) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-016-0978-9 · Cited by 20 · see citing works
Genetic variations of circulating adiponectin levels modulate changes in appetite in response to weight-loss diets
Ma, W., Huang, T., Heianza, Y., Wang, T., Sun, D., Tong, J., Williamson, D. A., Bray, G. A., Sacks, F. M., & Qi, L. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-2909 · Cited by 19 · see citing works
Impact of food restriction on the expression of the adiponectin system and genes in the hypothalamic-pituitary-ovarian axis of pre-pubertal ewes
Wang, R., Kuang, M., Nie, H., Bai, W., Sun, L., Wang, F., Mao, D., & Wang, Z. (2016) · Reproduction in Domestic Animals · doi:10.1111/rda.12727 · Cited by 18 · see citing works
Secretory activity of subcutaneous abdominal adipose tissue in male patients with rheumatoid arthritis and osteoarthritis – association with clinical and laboratory data
Kontny, E., Zielinska, A. E., Księżopolska-Orłowska, K., & Głuszko, P. (2016) · Reumatologia/Rheumatology · doi:10.5114/reum.2016.63662 · Cited by 16 · see citing works
Adipokines and Lipoproteins: Modulation by Antihyperglycemic and Hypolipidemic Agents
Rizvi, A. A., Nikolić, D., Sallam, H. S., Montalto, G., Rizzo, M., & Abate, N. I. (2013) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2013.0090 · Cited by 15 · see citing works
Association between uncoupling protein 2, adiponectin and resting energy expenditure in obese women with normal and low resting energy expenditure
Masoumi, Z. T., Eshraghian, M. R., Hedayati, M., & Pishva, H. (2017) · Gynecological Endocrinology · doi:10.1080/09513590.2017.1379492 · Cited by 16 · see citing works
Adiponectin: A potential candidate for treating fibrosis in posterior segment of the eye
Palanisamy, K., Raman, R., Sulochana, K. N., & Chidambaram, S. (2018) · Medical Hypotheses · doi:10.1016/j.mehy.2018.12.005 · Cited by 15 · see citing works
Short-term sympathoadrenal inhibition augments the thermogenic response to β-adrenergic receptor stimulation
Newsom, S. A., Richards, J. C., Johnson, T. K., Kuzma, J. N., Lonac, M. C., Paxton, R. J., Rynn, G. M., Voyles, W. F., & Bell, C. (2010) · Journal of Endocrinology · doi:10.1677/joe-10-0152 · Cited by 15 · see citing works
SGLT2 inhibition potentiates the cardiovascular, renal, and metabolic effects of sGC stimulation in hypertensive rats with prolonged exposure to high-fat diet
Reverte, V., Rodríguez, F., Oltra, L., Moreno, J. M., Llinás, M. T., Shea, C. M., Schwartzkopf, C. D., Buys, E. S., Masferrer, J. L., & Salazar, F. J. (2022) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00386.2021 · Cited by 14 · see citing works
Establishing a Reliable Multiple Reaction Monitoring-Based Method for the Quantification of Obesity-Associated Comorbidities in Serum and Adipose Tissue Requires Intensive Clinical Validation
Oberbach, A., Schlichting, N. S., Neuhaus, J., Kullnick, Y., Lehmann, S., Heinrich, M., Dietrich, A., Mohr, F. W., von Bergen�, M., & Baumann, S. (2014) · Journal of Proteome Research · doi:10.1021/pr500722k · Cited by 12 · see citing works
Functional characterisation of ADIPOQ variants using individuals recruited by genotype
Lee, B. P., Lloyd-Laney, H. O., Locke, J. M., McCulloch, L. J., Knight, B., Yaghootkar, H., Cory, G. O. C., Kos, K., Frayling, T. M., & Harries, L. W. (2016) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2016.03.020 · Cited by 12 · see citing works
Molecular Insights into Appetite Control and Neuroendocrine Disease as Risk Factors for Chronic Diseases in Western Countries
Martins, I. J., Creegan, R., Lim, W. L. F., & Martins, R. N. (2013) · Open Journal of Endocrine and Metabolic Diseases · doi:10.4236/ojemd.2013.35a002 · Cited by 11 · see citing works
Plasma adiponectin and depressive symptoms during pregnancy and the postpartum period: A prospective cohort study
Rebelo, F. M., Farias, D. R., Struchiner, C. J., & Kac, G. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.01.012 · Cited by 11 · see citing works
Effect of long-term feeding of the Obudu natural honey and table sugar-sweetened diets on obesity and pro-inflammatory biomarkers in rats
Atangwho, I. J., Ibeneme, C. E., Egbung, G. E., Ibeneme, E., Eno, M. A., & Nwankpa, P. (2020) · BMC Nutrition · doi:10.1186/s40795-019-0327-2 · Cited by 11 · see citing works
Effect of low-carbohydrate diet on adiponectin level in adults: a systematic review and dose-response meta-analysis of randomized controlled trials
Shemirani, F., Golzarand, M., Salari-Moghaddam, A., & Mahmoudi, M. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1871588 · Cited by 9 · see citing works
Adipose Tissue, Hormones, and Treatment of Type 1 Diabetes
Gunawardana, S. C. (2012) · Current Diabetes Reports · doi:10.1007/s11892-012-0300-9 · Cited by 8 · see citing works
COMPARISON OF AEROBIC, RESISTANCE AND CONCURRENT EXERCISE ON LIPID PROFILES AND ADIPONECTIN IN SEDENTARY MEN
Ali, A. M., & Abedi, B. (2012) · doi:10.22100/jkh.v7i1.116 · Cited by 9 · see citing works
Normal total and high molecular weight adiponectin levels in adults with cystic fibrosis
Ziai, S., Elisha, B., Hammana, I., Tardif, A., Berthiaume, Y., Coderre, L., & RABASA-LHORET, R. P. R. (2011) · Journal of Cystic Fibrosis · doi:10.1016/j.jcf.2011.07.005 · Cited by 8 · see citing works
Weight gain and changes in plasma adiponectin and leptin concentrations after 12-month insulin intensive therapy for Chinese male patients with newly diagnosed type 2 diabetes
Zhang, Q., Zhao, X., Chen, M., Fang, Z., Chen, Y., & Wang, Y. (2015) · Obesity Research & Clinical Practice · doi:10.1016/j.orcp.2015.09.005 · Cited by 7 · see citing works
Adiponectin moderates the relationship between adiposity and leptin in adolescents regardless of gender or race
Bundy, V. L., Johnson, M. H., Gutin, B., Zhu, H., Stallmann-Jorgensen, I. S., & Dong, Y. (2011) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem.2011.036 · Cited by 7 · see citing works
Milk-soluble formula increases food intake and reduces Il6 expression in elderly rat hypothalami
Hamouda, H. O., Delplanque, B., Benomar, Y., Crépin, D., Riffault, L., Leruyet, P., Bonhomme, C., & Taouis, M. (2015) · Journal of Endocrinology · doi:10.1530/joe-15-0076 · Cited by 5 · see citing works
Self-citation
Changes in serum adipokines during natural extended fasts in female northern elephant seals
Rzucidlo, C. L., Sperou, E. S., Holser, R. R., Khudyakov, J. I., da Costa, D. P., & Crocker, D. E. (2021) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2021.113760 · Cited by 5 · see citing works
Effects of order and sequence of resistance and endurance training on body fat in elementary school-aged girls
Alves, A. R., Marta, C., Neiva, H. P., Izquierdo, M., & Marques, M. C. (2017) · Biology of Sport · doi:10.5114/biolsport.2017.69826 · Cited by 4 · see citing works
Endocrine responses and food intake in fasted individuals under the influence of glucose ingestion
Nolde, J. M., Laupenmühlen, J., Al-Zubaidi, A., Heldmann, M., Münte, T. F., & Jauch‐Chara, K. (2019) · PLoS ONE · doi:10.1371/journal.pone.0211514 · Cited by 4 · see citing works
Cloning and Characterization of the 5′-Flanking Region of the Pig Cocaine- and Amphetamine-Regulated Transcript Gene
Ling, F., Wei, L., Wang, T., Chen, Y., Zhu, X., Li, J., Liu, T., Du, H., Wang, H., & Wang, J. (2010) · DNA and Cell Biology · doi:10.1089/dna.2010.1101 · Cited by 3 · see citing works
Hepatic glycogen participates in the regulation of hypothalamic pAkt/Akt ratio in high-sugar/high-fat diet-induced obesity
Casagrande, B. P., Bueno, A. A., Pisani, L. P., & Estadella, D. (2022) · Metabolic Brain Disease · doi:10.1007/s11011-022-00944-3 · Cited by 3 · see citing works
The Influence of Order Execution Components of the Strength and Endurance in the Concurrent Training on Lipid Profile and Body Composition in Overweight Females
Ali-Mohammadi, M., Abbaspoor, M., Rahimi, R., & Hakimi, M. (2014) · Cited by 3 · see citing works
The role of adiponectin in regulation of metabolism in dairy cows
Καλαμάρας, Κ. (2011) · doi:10.12681/eadd/51026 · Cited by 4 · see citing works
Type 2 diabetes: A side effect of the adaptation of neurons and fat cells to support increased cognitive performance
András, P., & Andras, A. (2012) · Medical Hypotheses · doi:10.1016/j.mehy.2012.11.023 · Cited by 2 · see citing works
The Effects of Short-term Circuit Resistance Training with Supplementation of Milk, Cheese Juice, Whey Protein on Resting Level Apolipoprotein M- HDL Total Cholesterol, Lipid Profile, Gastric Inhibitory Polypeptide and Plasma Estradiol in Untrained Young Men
Aalizadeh, A., Hossein, R., Ahmed, A., Rohbakhsh, E., Changizi‐Ashtiyani, S., & Abbas, G. (2016) · Journal of Applied Pharmaceutical Science · doi:10.7324/japs.2016.60319 · Cited by 2 · see citing works
Effect of Aerobic Exercise and Kefir Consumption on Anthropometric indices, Lipid Profile and Blood Pressure in Overweight Non-athletic Women
Safari, A., Moradi, M., & Khansooz, M. (2020) · مجله دانشگاه علوم پزشکی اراک · doi:10.32598/jams.23.2.4428.3 · Cited by 2 · see citing works
PHF5, a poly-herbal formulation with antidiabetic potential: in vitro and in silico investigation on HepG2 Cells via PKB/Akt and AMPK pathways
Egba, S. I., Ikechukwu, G. C., Omeoga, H. C., Uhuo, E. N., Ibeh, R. C., Okafor, P. N., & Mbah, P. (2025) · Applied Biological Chemistry · doi:10.1186/s13765-025-01041-6 · Cited by 1 · see citing works
THE EFFECTS OF THE TYPE OF EXERCISE ON LIPID PROFILES AND ADIPONECTIN LEVEL IN SEDENTARY MEN
Azarbayjani, M. A., Abedi, B., Peeri, M., Rasaee, M. J., & Ostojić, S. M. (2012) · University of Zagreb University Computing Centre (SRCE) · Cited by 1 · see citing works
The effect of resistance training with HMB supplementation on lipid profile and some physical fitness indicators of beginner bodybuilders
Ansari, S., Gholamrezaei, S., Moradnia, M., & AdibSaber, F. (2021) · فصلنامه علوم پزشکی دانشگاه آزاد اسلامی واحد پزشکی تهران · doi:10.52547/iau.31.2.164 · Cited by 1 · see citing works
The role of multiple regression analysis in prediction of insulin resistance in overweight and obese children
", & PAVLYSHYN, H. (2019) · Archives of the Balkan Medical Union · doi:10.31688/abmu.2019.54.3.18 · Cited by 1 · see citing works
The Effect of 12 weeks volleyball training on serum ghrelin levels in obese adult males
Hossain, T. L., Saifalddin, D. L., Ghanbari, N., & Mahmmod, B. N. (2019) · Halabja University Journal · doi:10.32410/huj-10246 · Cited by 1 · see citing works
Chronic North American Ginseng Administration Alters Metabolic and Cardiovascular Variables in the Rat
Migchels, M. J. (2012) · Scholarship@Western (Western University)
The low-density lipoprotein receptor knock-out mouse : a model for the study of energy balance
Ngai, Y. F. (2010) · cIRcle (University of British Columbia) · doi:10.14288/1.0069670
Stress and adiposity in children
Michels, N., & Huybrechts, I. (2016) · Ghent University Academic Bibliography (Ghent University)
Central Integration of Dietary Protein Signalling
Schwarz, J. (2010) · HAL
The Effect of Concurrent Training and Chlorogenic Acid Intake on Liver Enzymes and C-reactive Protein in Obese Women
Naderi, L., & Arabmomeni, A. (2019) · مجله دانشگاه علوم پزشکی اردبیل · doi:10.29252/jarums.19.3.284
Adiponectin in Cattle: Profiling of molecular weight patterns in different body fluids at different physiological states and assessment of adiponectin’s effects on lymphocytes
Heinz, J. F. L. (2014) · bonndoc (University of Bonn)
Effects of Porcine Adiponectin Ggene Polymorphismin the 5^|^prime;-Flanking Region on Backfat Thickness
CHIKUNI, K., Shibata, M., HORIUCHI, A., Hanako, I. D. E., Oe, M., Ojima, K., Muroya, S., & Nakajima, I. (2012) · Nihon Yoton Gakkaishi · doi:10.5938/youton.49.14

Adiponectin and energy homeostasis
Lee, B., & Shao, J. (2013) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-013-9283-3 · Cited by 171 · see citing works
The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS
Kadowaki, T., Yamauchi, T., & Kubota, N. (2007) · FEBS Letters · doi:10.1016/j.febslet.2007.11.070 · Cited by 270 · see citing works
Adiponectin: a Regulator of Energy Homeostasis
Wolf, G. (2003) · Nutrition Reviews · doi:10.1301/nr.2003.aug.290-292 · Cited by 77 · see citing works
Globular adiponectin regulates energy homeostasis through AMP-activated protein kinase–acetyl-CoA carboxylase (AMPK/ACC) pathway in the hypothalamus
Wen, J., Liu, C., Hu, Y., Chen, G., & Lin, L. (2010) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-010-0534-2 · Cited by 39 · see citing works
Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk
Stern, J. H., Rutkowski, J. M., & Scherer, P. E. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.04.011 · Cited by 1,031 · see citing works

Authors: Dridi, S., & Taouis, M.
Affiliations: University of Kentucky HealthCare (US)
Université Paris-Sud (FR)
Corresponding author: Dridi, Sami
ORCID: Dridi, Sami
Taouis, Mohammed
Venue: The Journal of Nutritional Biochemistry
Publisher: Elsevier BV
Published: 2009-11
Volume: 20
Issue: 11
Pages: 831-839
ISSN: 0955-2863 (ISSN-L)
DOI: 10.1016/j.jnutbio.2009.06.003
OpenAlex: W2015327820
Cited by: 85
References: 63
Citations by year: 2025: 1 · 2022: 2 · 2021: 3 · 2020: 3 · 2019: 4 · 2018: 4 · 2017: 3 · 2016: 10 · 2015: 5 · 2014: 7 · 2013: 7 · 2012: 13
FWCI: 1.46
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: The Journal of Nutritional Biochemistry (publishedVersion)
PubMed (publishedVersion)
HAL (submittedVersion)
Topics: Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
Health Sciences › Medicine › Physiology › Adipose Tissue and Metabolism
Keywords: adiponectin, energy homeostasis, glucose metabolism, fatty acid metabolism, hypothalamus, leptin, insulin, signal transduction
MeSH terms: Animals, Energy Metabolism, Homeostasis, Humans, Hypothalamus, Insulin, Signal Transduction, Leptin, Adiponectin, Receptors, Adiponectin

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Adiponectin and energy homeostasis: consensus and controversy

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