Morphogenesis and cell cycle progression in Candida albicans

Berman, Judith

doi:10.1016/j.mib.2006.10.007

Cited by 237Fungal and yeast genetics researchAntifungal resistance and susceptibilityFungal Infections and Studies

Morphogenesis and cell cycle progression in Candida albicans

Open access

Berman, Judith·2006·Current Opinion in Microbiology

DOI 10.1016/j.mib.2006.10.007PMC PMC3552184

Open this paper in CoChat — free account

Abstract

Candida albicans, an opportunistic human pathogen, displays three modes of growth: yeast, pseudohyphae and true hyphae, all of which differ both in morphology and in aspects of cell cycle progression. In particular, in hyphal cells, polarized growth becomes uncoupled from other cell cycle events. Yeast or pseudohyphae that undergo a cell cycle delay also exhibit polarized growth, independent of cell cycle progression. The Spitzenkörper, an organelle composed of vesicles associated with hyphal tips, directs continuous hyphal elongation in filamentous fungal species and also in C. albicans hyphae. A polarisome mediates cell cycle dependent growth in yeast and pseudohyphae. Regulation of morphogenesis and cell cycle progression is dependent upon specific cyclins, all of which affect morphogenesis and some of which function specifically in yeast or hyphal cells. Future work will probably focus on the cell cycle checkpoints involved in connecting morphogenesis to cell cycle progression.

Integrity signals

Registry

Crossref · 10.1016/j.mib.2006.10.007

Cites

47 of 47 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

One of the major features that distinguish true hyphae from yeast or pseudohyphae is their mode of cell cycle progression.
“One of the major features that distinguish true hyphae from yeast or pseudohyphae is their mode of cell cycle progression (Sudbery et al., 2004; Berman, 2006).”
From Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression inCandida albicans (2012) · cites this paper as Berman, 2006
Cell shape in C. albicans is tightly linked to regulation of cell cycle progression, and disruption of components of the cell cycle regulatory machinery has dramatic morphological consequences.
“Cell shape in C. albicans is tightly linked to regulation of cell cycle progression, and disruption of components of the cell cycle regulatory machinery has dramatic morphological consequences (Berman, 2006; Shapiro et al., 2011).”
From Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression inCandida albicans (2012) · cites this paper as Berman, 2006
C. albicans is a trimorphic fungus that can grow as unicellular budding yeast and in two filamentous, multicellular forms: hyphae and pseudohyphae.
“This trimorphic fungus can grow as unicellular budding yeast and in two filamentous, multicellular forms: hyphae and pseudohyphae.”
From Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression inCandida albicans (2012) · cites this paper as Berman, 2006
Pseudohyphae and hyphae are distinct morphologies: pseudohyphae resemble chains of elongated yeast cells, are wider than hyphae, and have clear constrictions at cellular junctions; hyphae are thinner, lack a constriction between mother and daughter cell, and have unconstricted septa.
“Pseudohyphae and hyphae are distinct morphologies. Pseudohyphae resemble chains of elongated yeast cells; they are wider than hyphae and have clear constrictions at cellular junctions. Hyphae are thinner, lack a constriction between the mother and daughter cell, and have unconstricted septa.”
From Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression inCandida albicans (2012) · cites this paper as Berman, 2006
In C. albicans, elongation in response to cell cycle arrest usually represents a terminal phenotype; cells continue to elongate for some time but never divide and eventually die.
“Elongation of C. albicans cells in response to cell cycle arrest usually represents a terminal phenotype. Although the cells continue to elongate for some time, they never divide and eventually die (Berman, 2006).”
From Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression inCandida albicans (2012) · cites this paper as Berman, 2006

The distinct morphogenic states of Candida albicans
Sudbery, P., Gow, N., & Berman, J. (2004) · Trends in Microbiology · doi:10.1016/j.tim.2004.05.008 · Cited by 876 · see citing works
Self-citation
EngineeredControl of Cell Morphology In Vivo Reveals Distinct Roles for Yeast andFilamentous Forms of Candida albicans duringInfection
Saville, S. P., Lazzell, A. L., Monteagudo, C., & Lopez-Ribot, J. L. (2003) · Eukaryotic Cell · doi:10.1128/ec.2.5.1053-1060.2003 · Cited by 655 · see citing works
Fungal morphogenesis and host invasion
Gow, N. A. R., Brown, A. J. P., & Odds, F. C. (2002) · Current Opinion in Microbiology · doi:10.1016/s1369-5274(02)00338-7 · Cited by 482 · see citing works
Ras Signaling Is Required for Serum-Induced Hyphal Differentiation in Candida albicans
Feng, Q., Summers, E., Guo, B., & Fink, G. R. (1999) · Journal of Bacteriology · doi:10.1128/jb.181.20.6339-6346.1999 · Cited by 347 · see citing works
Hgc1, a novel hypha‐specific G1 cyclin‐related protein regulates Candida albicans hyphal morphogenesis
Zheng, X., Wang, Y.-M., & Wang, Y. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600195 · Cited by 328 · see citing works
Induction of theCandida albicansFilamentous Growth Program by Relief of Transcriptional Repression: A Genome-wide Analysis
Kadosh, D., & Johnson, A. D. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-01-0073 · Cited by 285 · see citing works
Polarisome Meets Spitzenkorper: Microscopy, Genetics, and Genomics Converge
Harris, S. D., Read, N. D., Roberson, R. W., Shaw, B. D., Seiler, S., Plamann, M., & Momany, M. (2005) · Eukaryotic Cell · doi:10.1128/ec.4.2.225-229.2005 · Cited by 279 · see citing works
Symmetric cell division in pseudohyphae of the yeast Saccharomyces cerevisiae.
Kron, S. J., Styles, C. A., & Fink, G. R. (1994) · Molecular Biology of the Cell · doi:10.1091/mbc.5.9.1003 · Cited by 249 · see citing works
Cell cycle control of morphogenesis in budding yeast
Lew, D. J., & Reed, S. I. (1995) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(95)90048-9 · Cited by 234 · see citing works
Septin Function in Candida albicans Morphogenesis
Warenda, A. J., & Konopka, J. B. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.e02-01-0013 · Cited by 188 · see citing works
Candida albicans hyphae have a Spitzenkorper that is distinct from the polarisome found in yeast and pseudohyphae
Crampin, H., Finley, K. R., Gerami‐Nejad, M., Court, H., Gale, C. A., Berman, J. G., & Sudbery, P. E. (2005) · Journal of Cell Science · doi:10.1242/jcs.02414 · Cited by 187 · see citing works
Self-citation
The germ tubes of Candida albicans hyphae and pseudohyphae show different patterns of septin ring localization
Sudbery, P. E. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02459.x · Cited by 161 · see citing works
Release from Quorum-Sensing Molecules Triggers Hyphal Formation during Candida albicans Resumption of Growth
Enjalbert, B., & Whiteway, M. (2005) · Eukaryotic Cell · doi:10.1128/ec.4.7.1203-1210.2005 · Cited by 145 · see citing works
Comparative Gene Expression Analysis by a Differential Clustering Approach: Application to the Candida albicans Transcription Program
Ihmels, J., Bergmann, S., Berman, J. G., & Barkai, N. (2005) · PLoS Genetics · doi:10.1371/journal.pgen.0010039 · Cited by 131 · see citing works
Self-citation
Dominant negative selection of heterologous genes: isolation of Candida albicans genes that interfere with Saccharomyces cerevisiae mating factor-induced cell cycle arrest.
Whiteway, M., Dignard, D., & Thomas, D. Y. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.20.9410 · Cited by 130 · see citing works
A Forkhead Transcription Factor Is Important for True Hyphal as well as Yeast Morphogenesis in Candida albicans
Bensen, E. S., Filler, S. G., & Berman, J. G. (2002) · Eukaryotic Cell · doi:10.1128/ec.1.5.787-798.2002 · Cited by 122 · see citing works
Self-citation
The Spitzenkörper: a molecular perspective
Virag, A., & Harris, S. D. (2005) · Mycological Research · doi:10.1016/j.mycres.2005.09.005 · Cited by 114 · see citing works
Hyphal Elongation Is Regulated Independently of Cell Cycle inCandida albicans
Hazan, I., Sepulveda-Becerra, M., & Liu, H. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.01-03-0116 · Cited by 111 · see citing works
A G1 Cyclin Is Necessary for Maintenance of Filamentous Growth in Candida albicans
Loeb, J. D. J., Sepulveda-Becerra, M., Hazan, I., & Liu, H. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.6.4019 · Cited by 105 · see citing works
Cell cycle arrest during S or M phase generates polarized growth via distinct signals in Candida albicans
Bachewich, C., Nantel, A., & Whiteway, M. S. (2005) · Molecular Microbiology · doi:10.1111/j.1365-2958.2005.04727.x · Cited by 101 · see citing works
In Candida albicans , the Nim1 kinases Gin4 and Hsl1 negatively regulate pseudohypha formation and Gin4 also controls septin organization
Wightman, R., Bates, S., Amornrrattanapan, P., & Sudbery, P. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200307176 · Cited by 100 · see citing works
Late-G1 cyclin–CDK activity is essential for control of cell morphogenesis in budding yeast
Moffat, J., & Andrews, B. (2003) · Nature Cell Biology · doi:10.1038/ncb1078 · Cited by 94 · see citing works
The Mitotic Cyclins Clb2p and Clb4p Affect Morphogenesis inCandida albicans
Bensen, E. S., Clemente-Blanco, A., Finley, K. R., Correa-Bordes, J., & Berman, J. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-12-1081 · Cited by 94 · cited 8× · see citing works
“Adapted from Bensen et al. 2005.”
BackgroundInfluentialSelf-citation
Role for the SCF CDC4 Ubiquitin Ligase in Candida albicans Morphogenesis
Atir-Lande, A., Gildor, T., & Kornitzer, D. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-01-0079 · Cited by 90 · see citing works
Evolutionary Genomics: Yeasts Accelerate beyond BLAST
Wolfe, K. H. (2004) · Current Biology · doi:10.1016/j.cub.2004.05.015 · Cited by 89 · see citing works
Cyclin Cln3p Links G 1 Progression to Hyphal and Pseudohyphal Development in Candida albicans
Bachewich, C., & Whiteway, M. S. (2005) · Eukaryotic Cell · doi:10.1128/ec.4.1.95-102.2005 · Cited by 86 · see citing works
Temporal and Spatial Differences in Cell Wall Expansion during Bud and Mycelium Formation in Candida albicans
Staebell, M., & SOLL, D. R. (1985) · Microbiology · doi:10.1099/00221287-131-6-1467 · Cited by 85 · see citing works
Depletion of a Polo-like Kinase inCandida albicansActivates Cyclase-dependent Hyphal-like Growth
Bachewich, C., Thomas, D. Y., & Whiteway, M. S. (2003) · Molecular Biology of the Cell · doi:10.1091/mbc.02-05-0076 · Cited by 83 · see citing works
Candida albicansInt1p Interacts with the Septin Ring in Yeast and Hyphal Cells
Gale, C. A., Gerami‐Nejad, M., McClellan, M., Vandoninck, S., Longtine, M. S., & Berman, J. G. (2001) · Molecular Biology of the Cell · doi:10.1091/mbc.12.11.3538 · Cited by 81 · see citing works
Self-citation
The G 1 Cyclin Cln3 Regulates Morphogenesis in Candida albicans
Chapa‐y‐Lazo, B., Bates, S., & Sudbery, P. E. (2005) · Eukaryotic Cell · doi:10.1128/ec.4.1.90-94.2005 · Cited by 80 · see citing works
Asynchronous Cell Cycle and Asymmetric Vacuolar Inheritance in True Hyphae of Candida albicans
Barelle, C. J., Bohula, E. A., Kron, S. J., Wessels, D. J., Soll, D. R., Schäfer, A., Brown, A. J. P., & Gow, N. A. R. (2003) · Eukaryotic Cell · doi:10.1128/ec.2.3.398-410.2003 · Cited by 77 · see citing works
Hyphal Guidance and Invasive Growth in Candida albicans Require the Ras-Like GTPase Rsr1p and Its GTPase-Activating Protein Bud2p
Hausauer, D. L., Gerami‐Nejad, M., Kistler-Anderson, C., & Gale, C. A. (2005) · Eukaryotic Cell · doi:10.1128/ec.4.7.1273-1286.2005 · Cited by 75 · see citing works
Rad52 depletion in Candida albicans triggers both the DNA‐damage checkpoint and filamentation accompanied by but independent of expression of hypha‐specific genes
Andaluz, E., Ciudad, T., Gómez‐Raja, J., Calderone, R., & Larriba, G. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2005.05038.x · Cited by 69 · see citing works
Microtubules in Candida albicans Hyphae Drive Nuclear Dynamics and Connect Cell Cycle Progression to Morphogenesis
Finley, K. R., & Berman, J. (2005) · Eukaryotic Cell · doi:10.1128/ec.4.10.1697-1711.2005 · Cited by 66 · see citing works
Self-citation
Spindle assembly checkpoint component CaMad2p is indispensable for Candida albicans survival and virulence in mice
Bai, C. G., Ramanan, N., Wang, Y. M., & Wang, Y. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.02995.x · Cited by 64 · see citing works
The Cdc14p phosphatase affects late cell-cycle events and morphogenesis in Candida albicans
Clemente‐Blanco, A., González‐Novo, A., Machín, F., Caballero‐Lima, D., Aragón, L., Sánchez, M., de Aldana, C. R. V., Jiménez, J., & Correa‐Bordes, J. (2006) · Journal of Cell Science · doi:10.1242/jcs.02820 · Cited by 58 · see citing works
The regulation of nuclear migration and division during pseudo-mycelium outgrowth in the dimorphic yeast Candida albicans
Soll, D. R., Stasi, M., & Bedell, G. W. (1978) · Experimental Cell Research · doi:10.1016/0014-4827(78)90077-0 · Cited by 51 · see citing works
Induction ofS. cerevisiaeFilamentous Differentiation by Slowed DNA Synthesis Involves Mec1, Rad53 and Swe1 Checkpoint Proteins
Jiang, Y. W., & Kang, C. M. (2003) · Molecular Biology of the Cell · doi:10.1091/mbc.e03-06-0375 · Cited by 48 · see citing works
The GRR1 gene of Candida albicans is involved in the negative control of pseudohyphal morphogenesis
Butler, D. K., All, O., Goffena, J., Loveless, T., Wilson, T., & Toenjes, K. A. (2006) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2006.03.004 · Cited by 43 · see citing works
Molecular cloning and analysis of CDC28 and cyclin homologues from the human fungal pathogen Candida albicans
Sherlock, G. J., Bahman, A. M., Mahal, A., Shieh, J., Ferreira, M. G., & Rosamond, J. (1994) · Molecular and General Genetics MGG · doi:10.1007/bf00297278 · Cited by 42 · see citing works
The Involvement of Cell Wall Expansion in the Two Modes of Mycelium Formation of Candida albicans
Soll, D. R., Herman, M. A., & Staebell, M. (1985) · Microbiology · doi:10.1099/00221287-131-9-2367 · Cited by 41 · see citing works
The regulation of nuclear migration and division during synchronous bud formation in released stationary phase cultures of the yeast Candida albicans
Bedell, G. W., Werth, A., & Soll, D. R. (1980) · Experimental Cell Research · doi:10.1016/0014-4827(80)90418-8 · Cited by 40 · see citing works
Candida albicans VAC8 Is Required for Vacuolar Inheritance and Normal Hyphal Branching
Barelle, C. J., Richard, M. L., Gaillardin, C. M., Gow, N. A. R., & Brown, A. J. P. (2006) · Eukaryotic Cell · doi:10.1128/ec.5.2.359-367.2006 · Cited by 36 · see citing works
Deletion of the Dynein Heavy-Chain Gene DYN1 Leads to Aberrant Nuclear Positioning and Defective Hyphal Development in Candida albicans
Martin, R., Walther, A., & Wendland, J. (2004) · Eukaryotic Cell · doi:10.1128/ec.3.6.1574-1588.2004 · Cited by 35 · see citing works
Site Selection for Bud and Germ Tube Emergence in Candida albicans
Chaffin, W. L. (1984) · Microbiology · doi:10.1099/00221287-130-2-431 · Cited by 32 · see citing works
Repression of CDC28 reduces the expression of the morphology‐related transcription factors, Efg1p, Nrg1p, Rbf1p, Rim101p, Fkh2p and Tec1p and induces cell elongation in Candida albicans
Umeyama, T., Kaneko, A., Niimi, M., & Uehara, Y. (2006) · Yeast · doi:10.1002/yea.1373 · Cited by 31 · see citing works
ABG1 , a Novel and Essential Candida albicans Gene Encoding a Vacuolar Protein Involved in Cytokinesis and Hyphal Branching
Veses, V., Casanova, M., Murgui, A., Domínguez, Á., Gow, N. A. R., & Martínez, J. P. (2005) · Eukaryotic Cell · doi:10.1128/ec.4.6.1088-1101.2005 · Cited by 22 · see citing works

Flagged first, then by citations

Sorted by citations

Growth of Candida albicans hyphae
Sudbery, P. E. (2011) · Nature Reviews Microbiology · doi:10.1038/nrmicro2636 · Cited by 1,110 · see citing works
Regulatory circuitry governing fungal development, drug resistance, and disease.
Shapiro, R. S., Robbins, N., & Cowen, L. E. (2011) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00045-10 · Cited by 576 · see citing works
Environmental Sensing and Signal Transduction Pathways Regulating Morphopathogenic Determinants of Candida albicans
Biswas, S., Dijck, P. V., & Datta, A. (2007) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00009-06 · Cited by 516 · see citing works
Morphogenesis in Candida albicans
Whiteway, M. S., & Bachewich, C. (2007) · Annual Review of Microbiology · doi:10.1146/annurev.micro.61.080706.093341 · Cited by 390 · see citing works
The Regulation of Filamentous Growth in Yeast
Cullen, P. J., & Sprague, G. F. (2012) · Genetics · doi:10.1534/genetics.111.127456 · Cited by 273 · see citing works
Global analysis of fungal morphology exposes mechanisms of host cell escape
O’Meara, T. R., Veri, A. O., Ketela, T., Jiang, B., Roemer, T., & Cowen, L. E. (2015) · Nature Communications · doi:10.1038/ncomms7741 · Cited by 243 · see citing works
The effect of Streptococcus mutans and Candida glabrata on Candida albicans biofilms formed on different surfaces
Pereira‐Cenci, T., Deng, D., Kraneveld, E. A., Manders, E. M. M., Cury, A. A. D. B., ten Cate, J. M., & Wim Crielaard, A. (2008) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2008.02.015 · Cited by 181 · see citing works
Yeasts in the Gut
Schulze, J., & Sonnenborn, U. (2009) · Deutsches Ärzteblatt international · doi:10.3238/arztebl.2009.0837 · Cited by 170 · see citing works
Cryptococcus neoformans: Morphogenesis, infection, and evolution
Lin, X. (2009) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2009.01.013 · Cited by 166 · see citing works
Arginine-Induced Germ Tube Formation in Candida albicans Is Essential for Escape from Murine Macrophage Line RAW 264.7
Ghosh, S., Navarathna, D. H. M. L. P., Roberts, D. D., Cooper, J. T., Atkin, A. L., Petro, T. M., & Nickerson, K. W. (2009) · Infection and Immunity · doi:10.1128/iai.01452-08 · Cited by 165 · see citing works
Streptococcus mutans Inhibits Candida albicans Hyphal Formation by the Fatty Acid Signaling Molecule trans‐2‐Decenoic Acid (SDSF)
Vilchez‐Vargas, R., Lemme, A., Ballhausen, B., Thiel, V., Schulz, S., Jansen, R., Sztajer, H., & Wagner‐Döbler, I. (2010) · ChemBioChem · doi:10.1002/cbic.201000086 · Cited by 146 · see citing works
Modulation of Morphogenesis in Candida albicans by Various Small Molecules
Shareck, J., & Belhumeur, P. (2011) · Eukaryotic Cell · doi:10.1128/ec.05030-11 · Cited by 142 · see citing works
From Jekyll to Hyde: The Yeast–Hyphal Transition of Candida albicans
Chow, E. W. L., Pang, L. M., & Wang, Y. (2021) · Pathogens · doi:10.3390/pathogens10070859 · Cited by 144 · see citing works
Histone acetyltransferase Rtt109 is required for Candida albicans pathogenesis
Lopes da Rosa, J., Boyartchuk, V. L., Zhu, L. J., & Kaufman, P. D. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0912427107 · Cited by 132 · see citing works
Candida albicans Hyphae: From Growth Initiation to Invasion
Desai, J. (2018) · Journal of Fungi · doi:10.3390/jof4010010 · Cited by 117 · see citing works
Regulation of Candida albicans Hyphal Morphogenesis by Endogenous Signals
Kornitzer, D. (2019) · Journal of Fungi · doi:10.3390/jof5010021 · Cited by 105 · see citing works
UME6 is a crucial downstream target of other transcriptional regulators of true hyphal development in Candida albicans
Zeidler, U., Lettner, T., Lassnig, C., ller, M. M. ⁄., Lajko, R., Hintner, H., Breitenbach, M., & Bito, A. (2008) · FEMS Yeast Research · doi:10.1111/j.1567-1364.2008.00459.x · Cited by 104 · see citing works
Candida albicans Heat Shock Proteins and Hsps-Associated Signaling Pathways as Potential Antifungal Targets
Gong, Y., Li, T., Yu, C., & Sun, S. (2017) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2017.00520 · Cited by 101 · see citing works
Pseudohyphal growth of the emerging pathogen Candida auris is triggered by genotoxic stress through the S phase checkpoint
Bravo Ruiz, G., Ross, Z. K., Gow, N. A. R., & Lorenz, A. (2020) · mSphere · doi:10.1128/msphere.00151-20 · Cited by 101 · see citing works
Paradoxical Growth of Candida albicans in the Presence of Caspofungin Is Associated with Multiple Cell Wall Rearrangements and Decreased Virulence
Rueda, C., Cuenca‐Estrella, M., & Zaragoza, Ó. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00946-13 · Cited by 98 · see citing works
Profiling a killer, the development of Cryptococcus neoformans
Kozubowski, L., & Heitman, J. (2011) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2011.00286.x · Cited by 97 · see citing works
Enhanced germicidal effects of pulsed UV-LED irradiation on biofilms
Li, J., Hirota, K., Yumoto, H., Matsuo, T., Miyake, Y., & Ichikawa, T. (2010) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2010.04850.x · Cited by 92 · see citing works
Mitochondrial proline catabolism activates Ras1/cAMP/PKA-induced filamentation in Candida albicans
Silao, F. G. S., Ward, M., Ryman, K., Wallström, A., Brindefalk, B., Udekwu, K., & Ljungdahl, P. O. (2019) · PLOS Genetics · doi:10.1371/journal.pgen.1007976 · Cited by 93 · see citing works
The Hsp90 Co-Chaperone Sgt1 Governs Candida albicans Morphogenesis and Drug Resistance
Shapiro, R. S., Zaas, A. K., Betancourt-Quiroz, M., Perfect, J. R., & Cowen, L. E. (2012) · PLoS ONE · doi:10.1371/journal.pone.0044734 · Cited by 86 · see citing works
The Candida albicans-Specific Gene EED1 Encodes a Key Regulator of Hyphal Extension
Martin, R., Moran, G. P., Jacobsen, I. D., Heyken, A., Domey, J., Sullivan, D. J., Kurzai, O., & Hube, B. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018394 · Cited by 85 · see citing works
Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets
Fu, C., Zhang, X., Veri, A. O., Iyer, K. R., Lash, E., Xue, A., Yan, H., Revie, N. M., Wong, C. J., Lin, Z., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-26850-3 · Cited by 82 · see citing works
Candida albicans cell shaving uncovers new proteins involved in cell wall integrity, yeast to hypha transition, stress response and host–pathogen interaction
Gil-Bona, A., Parra‐Giraldo, C. M., Hernáez, M. L., Reales‐Calderón, J. A., Solis, N. V., Filler, S. G., Monteoliva, L., & Gil, C. (2015) · Journal of Proteomics · doi:10.1016/j.jprot.2015.06.006 · Cited by 78 · see citing works
Human Milk Oligosaccharides Inhibit Candida albicans Invasion of Human Premature Intestinal Epithelial Cells ,
Gonia, S., Tuepker, M., Heisel, T. J., Autran, C. A., Bode, L., & Gale, C. A. (2015) · Journal of Nutrition · doi:10.3945/jn.115.214940 · Cited by 78 · see citing works
Ser/Thr protein phosphatases in fungi: structure, regulation and function
Ariño, J., Velázquez, D., & Casamayor, A. (2019) · Microbial Cell · doi:10.15698/mic2019.05.677 · Cited by 76 · see citing works
Highly Potential Antifungal Activity of Quantum-Sized Silver Nanoparticles Against Candida albicans
Selvaraj, M., Pandurangan, P., Ramasami, N., Rajendran, S. B., Sangilimuthu, S. N., & Perumal, P. (2014) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-014-0782-9 · Cited by 75 · see citing works
Dancing genomes: fungal nuclear positioning
Gladfelter, A. S., & Berman, J. G. (2009) · Nature Reviews Microbiology · doi:10.1038/nrmicro2249 · Cited by 74 · see citing works
Self-citation
Transcriptional Analysis of the Candida albicans Cell Cycle
Côte, P., Hogues, H., & Whiteway, M. (2009) · Molecular Biology of the Cell · doi:10.1091/mbc.e09-03-0210 · Cited by 72 · see citing works
Capsule Growth in Cryptococcus neoformans Is Coordinated with Cell Cycle Progression
García‐Rodas, R., Cordero, R. J. B., Trevijano‐Contador, N., Janbon, G., Moyrand, F., Casadevall, A., & Zaragoza, Ó. (2014) · mBio · doi:10.1128/mbio.00945-14 · Cited by 73 · see citing works
The Candida albicans pescadillo homolog is required for normal hypha-to-yeast morphogenesis and yeast proliferation
Shen, J., Cowen, L. E., Griffin, A. M., Chan, L. Y., & Köhler, J. R. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0809147105 · Cited by 70 · see citing works
Effect of Growth Media, pH and Temperature on Yeast to Hyphal Transition in Candida albicans
Nadeem, S. G., Shafiq, A., Hakim, S. T., Anjum, Y., & Kazm, S. U. (2013) · Open Journal of Medical Microbiology · doi:10.4236/ojmm.2013.33028 · Cited by 66 · see citing works
Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression inCandida albicans
Senn, H., Shapiro, R. S., & Cowen, L. E. (2012) · Molecular Biology of the Cell · doi:10.1091/mbc.e11-08-0729 · Cited by 67 · see citing works
Ras Signaling Gets Fine-Tuned: Regulation of Multiple Pathogenic Traits of Candida albicans
Inglis, D. O., & Sherlock, G. (2013) · Eukaryotic Cell · doi:10.1128/ec.00094-13 · Cited by 65 · see citing works
Aspartic protease inhibitors as potential anti-Candida albicans drugs: impacts on fungal biology, virulence and pathogenesis.
Braga-Silva, L. A., & Santos, A. L. S. (2011) · Current Medicinal Chemistry · doi:10.2174/092986711795843182 · Cited by 64 · see citing works
Response and regulatory mechanisms of heat resistance in pathogenic fungi
Xiao, W., Zhang, J., Huang, J., Xin, C., Li, M. J., & Song, Z. (2022) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-022-12119-2 · Cited by 61 · see citing works
Vacuole dynamics in fungi
Richards, A., Veses, V., & Gow, N. A. R. (2010) · Fungal Biology Reviews · doi:10.1016/j.fbr.2010.04.002 · Cited by 61 · see citing works
Parylene coating hinders Candida albicans adhesion to silicone elastomers and denture bases resin
Zhou, L., Tong, Z., Wu, G., Feng, Z., Bai, S., Dong, Y., Ni, L., & Zhao, Y. (2010) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2010.03.013 · Cited by 59 · see citing works
A Comprehensive Functional Portrait of Two Heat Shock Factor-Type Transcriptional Regulators Involved in Candida albicans Morphogenesis and Virulence
Znaidi, S., Nesseir, A., Chauvel, M., Rossignol, T., & d’Enfert, C. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003519 · Cited by 58 · see citing works
The Yak1 Kinase Is Involved in the Initiation and Maintenance of Hyphal Growth inCandida albicans
Goyard, S., Knechtle, P., Chauvel, M., Mallet, A., Prévost, M., Proux, C., Coppée, J., Schwarz, P., Dromer, F., Park, H., et al. (2008) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-09-0960 · Cited by 59 · see citing works
Cinnamomum zeylanicum bark essential oil induces cell wall remodelling and spindle defects in Candida albicans
Shahina, Z., El-Ganiny, A. M., Minion, J., Whiteway, M. S., Sultana, T., & Dahms, T. E. S. (2018) · Fungal Biology and Biotechnology · doi:10.1186/s40694-018-0046-5 · Cited by 57 · see citing works
“Repair Me if You Can”: Membrane Damage, Response, and Control from the Viral Perspective
Daussy, C. F., & Wodrich, H. (2020) · Cells · doi:10.3390/cells9092042 · Cited by 52 · see citing works
Antifungal properties of Canavalia ensiformis urease and derived peptides
Postal, M., Martinelli, A. H. S., Becker‐Ritt, A. B., Ligabue‐Braun, R., Demartini, D. R., Ribeiro, S. F. F., Pasquali, G., Gomes, V. M., & Carlini, C. R. (2012) · Peptides · doi:10.1016/j.peptides.2012.08.010 · Cited by 55 · see citing works
Forward genetics in Candida albicans that reveals the Arp2/3 complex is required for hyphal formation, but not endocytosis
Epp, E., Walther, A., Lépine, G., Leon, Z., Mullick, A., Raymond, M., Wendland, J., & Whiteway, M. S. (2010) · Molecular Microbiology · doi:10.1111/j.1365-2958.2009.07038.x · Cited by 53 · see citing works
Urban legends series: oral candidosis.
Manfredi, M., Polonelli, L., Aguirre-Urizar, J., Carrozzo, M., & McCullough, M. (2013) · Oral Diseases · doi:10.1111/odi.12013 · Cited by 48 · see citing works
Phenotypic Profiling Reveals that Candida albicans Opaque Cells Represent a Metabolically Specialized Cell State Compared to Default White Cells
Ene, I. V., Lohse, M. B., Vladu, A., Morschhäuser, J., Johnson, A. D., & Bennett, R. J. (2016) · mBio · doi:10.1128/mbio.01269-16 · Cited by 50 · see citing works
Vacuole inheritance regulates cell size and branching frequency of Candida albicans hyphae
Veses, V., Richards, A., & Gow, N. A. R. (2008) · Molecular Microbiology · doi:10.1111/j.1365-2958.2008.06545.x · Cited by 50 · see citing works
Hsp90-dependent regulatory circuitry controlling temperature-dependent fungal development and virulence: Hsp90 and fungal development
O'Meara, T. R., & Cowen, L. E. (2014) · Cellular Microbiology · doi:10.1111/cmi.12266 · Cited by 48 · see citing works
Dynein-dependent nuclear dynamics affect morphogenesis inCandida albicansby means of the Bub2p spindle checkpoint
Finley, K. R., Bouchonville, K. J., Quick, A., & Berman, J. G. (2008) · Journal of Cell Science · doi:10.1242/jcs.015172 · Cited by 48 · see citing works
Self-citation
CDKs and the yeast-hyphal decision
Wang, Y. (2009) · Current Opinion in Microbiology · doi:10.1016/j.mib.2009.09.002 · Cited by 47 · see citing works
Bypass of Candida albicans Filamentation/Biofilm Regulators through Diminished Expression of Protein Kinase Cak1
Woolford, C. A., Lagree, K., Xu, W., Aleynikov, T., Adhikari, H., Sánchez, H., Cullen, P. J., Lanni, F., Andes, D. R., & Mitchell, A. P. (2016) · PLoS Genetics · doi:10.1371/journal.pgen.1006487 · Cited by 46 · see citing works
Candida albicans cell wall components and farnesol stimulate the expression of both inflammatory and regulatory cytokines in the murine RAW264.7 macrophage cell line
Ghosh, S., Howe, N., Volk, K., Tati, S., Nickerson, K. W., & Petro, T. M. (2010) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2010.00717.x · Cited by 47 · see citing works
Changes in glutathione-dependent redox status and mitochondrial energetic strategies are part of the adaptive response during the filamentation process in Candida albicans
Guedouari, H., Gergondey, R., Bourdais, A., Vanparis, O., Bulteau, A. L., Camadro, J. M., & Auchère, F. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2014.07.006 · Cited by 45 · see citing works
Asp1, a Conserved 1/3 Inositol Polyphosphate Kinase, Regulates the Dimorphic Switch in Schizosaccharomyces pombe
Pöhlmann, J., & Fleig, U. N. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.00472-10 · Cited by 45 · see citing works
Quantitative Proteome and Acidic Subproteome Profiling of Candida albicans Yeast-to-Hypha Transition
Monteoliva, L., Martínez‐López, R., Pitarch, A., Hernáez, M. L., Serna, A., Nombela, C., Albar, J. P., & Gil, C. (2010) · Journal of Proteome Research · doi:10.1021/pr100710g · Cited by 44 · see citing works
Honey Flavonoids Inhibit Candida albicans Morphogenesis by Affecting DNA Behavior and Mitochondrial Function
Canonico, B., Candiracci, M., Citterio, B., Curci, R., Squarzoni, S., Mazzoni, A., Papa, S., & Piatti, E. (2014) · Future Microbiology · doi:10.2217/fmb.14.17 · Cited by 42 · see citing works
Paracoccidioides brasiliensis: chemical and molecular tools for research on cell walls, antifungals, diagnosis, taxonomy
San-Blas, G., & Niño‐Vega, G. A. (2008) · Mycopathologia · doi:10.1007/s11046-007-9040-9 · Cited by 41 · see citing works
Pseudohypha budding patterns of Candida albicans
Veses, V., & Gow, N. A. R. (2009) · Medical Mycology · doi:10.1080/13693780802245474 · Cited by 41 · see citing works
Appressorium morphogenesis and cell cycle progression are linked in the grass powdery mildew fungus Blumeria graminis
Hansjakob, A., Riederer, M., & Hildebrandt, U. (2012) · Fungal Biology · doi:10.1016/j.funbio.2012.05.006 · Cited by 40 · see citing works
Mechanistic insights into Candida biofilm eradication potential of eucalyptol
Gupta, P., Pruthi, V., & Poluri, K. M. (2020) · Journal of Applied Microbiology · doi:10.1111/jam.14940 · Cited by 40 · see citing works
The Cyclin Cln1 Controls Polyploid Titan Cell Formation following a Stress-Induced G2 Arrest in Cryptococcus
Altamirano, S., Li, Z.-M., Fu, M., Ding, M., Fulton, S. R., Yoder, J., Tran, V., & Nielsen, K. (2021) · bioRxiv · doi:10.1128/mbio.02509-21 · Cited by 35 · see citing works
G 1 /S Transcription Factor Orthologues Swi4p and Swi6p Are Important but Not Essential for Cell Proliferation and Influence Hyphal Development in the Fungal Pathogen Candida albicans
Hussein, B., Huang, H., Glory, A., Osmani, A., Kaminskyj, S. G. W., Nantel, A., & Bachewich, C. (2011) · Eukaryotic Cell · doi:10.1128/ec.00278-10 · Cited by 39 · see citing works
Distinct roles of two ceramide synthases, CaLag1p and CaLac1p, in the morphogenesis of Candida albicans
Cheon, S. A., Bal, J., Song, Y., Hwang, H., Kim, A. R., Kang, W. K., Kang, H. A., Hannibal‐Bach, H. K., Knudsen, J., Ejsing, C. S., et al. (2011) · Molecular Microbiology · doi:10.1111/j.1365-2958.2011.07961.x · Cited by 39 · see citing works
Suppression of hyphal formation and virulence of Candida albicans by natural and synthetic compounds
Khan, F., Bamunuarachchi, N. I., Tabassum, N., Jo, D., Khan, P. D. M. M., & Kim, Y. (2021) · Biofouling · doi:10.1080/08927014.2021.1948538 · Cited by 37 · see citing works
Morphogenic plasticity: the pathogenic attribute of Candida albicans
Prasad, P., & Tippana, M. (2023) · Current Genetics · doi:10.1007/s00294-023-01263-5 · Cited by 40 · see citing works
A Candida albicans cell wall-linked protein promotes invasive filamentation into semi-solid medium
Zucchi, P., Davis, T. R., & Kumamoto, C. A. (2010) · Molecular Microbiology · doi:10.1111/j.1365-2958.2010.07137.x · Cited by 36 · see citing works
Galectins in Host Defense Against Microbial Infections
Li, F.-Y., Wang, S., Bernardes, E. S., & Liu, F. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-981-15-1580-4_6 · Cited by 35 · see citing works
The Candida albicans ELMO homologue functions together with Rac1 and Dck1, upstream of the MAP Kinase Cek1, in invasive filamentous growth
Hope, H., Schmauch, C., Arkowitz, R. A., & Bassilana, M. (2010) · Molecular Microbiology · doi:10.1111/j.1365-2958.2010.07186.x · Cited by 34 · see citing works
An Overview of Autophagy and Yeast Pseudohyphal Growth: Integration of Signaling Pathways during Nitrogen Stress
Song, Q., & Kumar, A. (2012) · Cells · doi:10.3390/cells1030263 · Cited by 35 · see citing works
Regulatory network controls microbial biofilm development, with Candida albicans as a representative: from adhesion to dispersal
Xu, Z., Huang, T., Du, ‬., Soteyome, T., Lan, H., Hong, W., Peng, F., Fu, X., Peng, G., Liu, J., et al. (2021) · Bioengineered · doi:10.1080/21655979.2021.1996747 · Cited by 34 · see citing works
Retracted
CaMtw1, a member of the evolutionarily conserved Mis12 kinetochore protein family, is required for efficient inner kinetochore assembly in the pathogenic yeast Candida albicans
Roy, B., Burrack, L. S., Lone, M. A., Berman, J. G., & Sanyal, K. (2011) · Molecular Microbiology · doi:10.1111/j.1365-2958.2011.07558.x · Cited by 33 · see citing works
Self-citation
MAPK Cell-Cycle Regulation in Saccharomyces Cerevisiae and Candida Albicans
Correia, I., Alonso‐Monge, R., & Plá, J. (2010) · Future Microbiology · doi:10.2217/fmb.10.72 · Cited by 33 · see citing works
Glutamate dehydrogenase (Gdh2)-dependent alkalization is dispensable for escape from macrophages and virulence of Candida albicans
Silao, F. G. S., Ryman, K., Jiang, T., Ward, M., Hansmann, N., Molenaar, C., Liu, N.-N., Chen, C., & Ljungdahl, P. O. (2020) · PLOS Pathogens · doi:10.1371/journal.ppat.1008328 · Cited by 32 · see citing works
Functional connections between cell cycle and proteostasis in the regulation of Candida albicans morphogenesis
Hossain, S., Lash, E., Veri, A. O., & Cowen, L. E. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.108781 · Cited by 31 · see citing works
The two‐component response regulator Skn7 belongs to a network of transcription factors regulating morphogenesis in Candida albicans and independently limits morphogenesis‐induced ROS accumulation
Basso, V., Znaidi, S., Lagage, V., Cabral, V., Schönherr, F. A., LeibundGut‐Landmann, S., d’Enfert, C., & Bachellier‐Bassi, S. (2017) · Molecular Microbiology · doi:10.1111/mmi.13758 · Cited by 33 · see citing works
Phr1p, a glycosylphosphatidylinsitol-anchored β(1,3)-glucanosyltransferase critical for hyphal wall formation, localizes to the apical growth sites and septa in Candida albicans
Ragni, E., Calderon, J., Fascio, U., Sipiczki, M., Fonzi, W. A., & Popolo, L. (2011) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2011.05.003 · Cited by 30 · see citing works
HIV aspartyl protease inhibitors as promising compounds againstCandida albicansAndré Luis Souza dos Santos
dos Santos, A. L. S. (2010) · World Journal of Biological Chemistry · doi:10.4331/wjbc.v1.i2.21 · Cited by 35 · see citing works
Microtubule Motor Protein Kar3 Is Required for Normal Mitotic Division and Morphogenesis in Candida albicans
Sherwood, R. K., & Bennett, R. J. (2008) · Eukaryotic Cell · doi:10.1128/ec.00138-08 · Cited by 30 · see citing works
Farnesol inhibits translation to limit growth and filamentation in C. albicans and S. cerevisiae
Egbe, N. E., Dornelles, T., Paget, C. M., Castelli, L. M., & Ashe, M. (2017) · Microbial Cell · doi:10.15698/mic2017.09.589 · Cited by 30 · see citing works
The RIM101 Signal Transduction Pathway Regulates Candida albicans Virulence during Experimental Keratomycosis
Yuan, X., Mitchell, B. M., Hua, X., Davis, D. A., & Wilhelmus, K. R. (2010) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.09-4726 · Cited by 30 · see citing works
Anti-Candida activity of 1–18 fragment of the frog skin peptide esculentin-1b: in vitro and in vivo studies in a Caenorhabditis elegans infection model
Luca, V., Olivi, M., Grazia, A. D., Palleschi, C., Uccelletti, D., & Mangoni, M. L. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1500-4 · Cited by 29 · see citing works
Monitoring Phenotypic Switching in Candida albicans and the Use of Next‐Gen Fluorescence Reporters
Frazer, C., Hernday, A. D., & Bennett, R. J. (2019) · Current Protocols in Microbiology · doi:10.1002/cpmc.76 · Cited by 29 · see citing works
Growth phase-dependent variations in transcript profiles for thioredoxin- and glutathione-dependent redox systems followed by budding and hyphalCandida albicans cultures
Michán, C., & Pueyo, C. (2009) · FEMS Yeast Research · doi:10.1111/j.1567-1364.2009.00558.x · Cited by 29 · see citing works
Identification of salivary components that induce transition of hyphae to yeast inCandida albicans
Leito, J. T. D., Ligtenberg, A. J. M., Nazmi, K., & Veerman, E. C. I. (2009) · FEMS Yeast Research · doi:10.1111/j.1567-1364.2009.00575.x · Cited by 29 · see citing works
Differential Involvement of Histidine Kinase Receptors in Pseudohyphal Development, Stress Adaptation, and Drug Sensitivity of the Opportunistic Yeast Candida lusitaniae
Chapeland‐Leclerc, F., Paccallet, P., Ruprich‐Robert, G., Reboutier, D., Chastin, C., & Papon, N. (2007) · Eukaryotic Cell · doi:10.1128/ec.00155-07 · Cited by 28 · see citing works
A MAP Kinase Pathway Is Implicated in the Pseudohyphal Induction by Hydrogen Peroxide in Candica albicans
Srinivasa, K., Kim, J., Yee, S.-B., Kim, W., & Choi, W. (2012) · Molecules and Cells · doi:10.1007/s10059-012-2244-y · Cited by 28 · see citing works
The Hog1 MAP Kinase Promotes the Recovery from Cell Cycle Arrest Induced by Hydrogen Peroxide in Candida albicans
Correia, I., Alonso‐Monge, R., & Plá, J. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.02133 · Cited by 28 · see citing works
Polarized growth in fungi: Symmetry breaking and hyphal formation
Arkowitz, R. A., & Bassilana, M. (2011) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2011.08.010 · Cited by 27 · see citing works
Orchestrated actin nucleation by the Candida albicans polarisome complex enables filamentous growth
Xie, Y., Loh, Z. Y., Xue, J., Zhou, F., Sun, J., Qiao, Z., Jin, S., Deng, Y., Li, H., Wang, Y., et al. (2020) · Journal of Biological Chemistry · doi:10.1074/jbc.ra120.013890 · Cited by 26 · see citing works
Physiological adventures in Candida albicans : farnesol and ubiquinones
Nickerson, K. W., Gutzmann, D. J., Boone, C. H. T., Pathirana, R. U., & Atkin, A. L. (2024) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00081-22 · Cited by 26 · see citing works
Candida albicans AGE3, the Ortholog of the S. cerevisiae ARF-GAP-Encoding Gene GCS1, Is Required for Hyphal Growth and Drug Resistance
Lettner, T., Zeidler, U., Gimona, M., Hauser, M., Breitenbach, M., & Bito, A. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011993 · Cited by 26 · see citing works
The adaptive response to iron involves changes in energetic strategies in the pathogen Candida albicans
Duval, C., Macabiou, C., Garcia, C., Lesuisse, E., Camadro, J., & Auchère, F. (2019) · MicrobiologyOpen · doi:10.1002/mbo3.970 · Cited by 24 · see citing works
Candida albicans exhibits heterogeneous and adaptive cytoprotective responses to antifungal compounds
Dumeaux, V., Massahi, S., Bettauer, V., Mottola, A., Dukovny, A., Khurdia, S. S., Costa, A. C. B. P., Omran, R. P., Simpson, S., Xie, J. L., et al. (2023) · eLife · doi:10.7554/elife.81406 · Cited by 25 · see citing works
Self-citation
A Comparative Review of Eugenol and Citral Anticandidal Mechanisms: Partners in Crimes Against Fungi
Shahina, Z., & Dahms, T. E. S. (2024) · Molecules · doi:10.3390/molecules29235536 · Cited by 29 · see citing works
Role of Cln1 during melanization of Cryptococcus neoformans
García‐Rodas, R., Trevijano‐Contador, N., Román, E., Janbon, G., Moyrand, F., Plá, J., Casadevall, A., & Zaragoza, Ó. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00798 · Cited by 24 · see citing works
The Candida albicans Rgd1 is a RhoGAP protein involved in the control of filamentous growth
Ness, F., Prouzet‐Mauleon, V., Vieillemard, A., Lefebvre, F., Noël, T., Crouzet, M., Doignon, F., & Thoraval, D. H. (2010) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2010.07.007 · Cited by 24 · see citing works
Candidacidal mechanism of the arenicin-3-derived peptide NZ17074 from Arenicola marina
Wang, X., Wang, X., Teng, D., Zhang, Y., Mao, R., Xi, D., & Wang, J. (2014) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-014-5784-6 · Cited by 24 · see citing works

Hyphal Elongation Is Regulated Independently of Cell Cycle inCandida albicans
Hazan, I., Sepulveda-Becerra, M., & Liu, H. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.01-03-0116 · Cited by 111 · see citing works
Morphogenesis in Candida albicans: How to Stay Focused
Bassilana, M., & Follette, P. J. (2011) · Topics in current genetics · doi:10.1007/978-3-642-22916-9_8 · Cited by 1 · see citing works
Candida albicans hyphae have a Spitzenkorper that is distinct from the polarisome found in yeast and pseudohyphae
Crampin, H., Finley, K. R., Gerami‐Nejad, M., Court, H., Gale, C. A., Berman, J. G., & Sudbery, P. E. (2005) · Journal of Cell Science · doi:10.1242/jcs.02414 · Cited by 187 · see citing works
Self-citation
Cell Cycle and Growth Control inCandidaSpecies
Gale, C. A., & Berman, J. G. (2014) · ASM Press eBooks · doi:10.1128/9781555817176.ch8 · Cited by 1 · see citing works
Self-citation
Depletion of a Polo-like Kinase inCandida albicansActivates Cyclase-dependent Hyphal-like Growth
Bachewich, C., Thomas, D. Y., & Whiteway, M. S. (2003) · Molecular Biology of the Cell · doi:10.1091/mbc.02-05-0076 · Cited by 83 · see citing works

Authors: Berman, J.
Affiliations: University of Minnesota (US)
Corresponding author: Berman, Judith
ORCID: Berman, Judith
Venue: Current Opinion in Microbiology
Publisher: Elsevier BV
Published: 2006-12
Volume: 9
Issue: 6
Pages: 595-601
ISSN: 1369-5274 (ISSN-L)
DOI: 10.1016/j.mib.2006.10.007
PMC: PMC3552184
OpenAlex: W2135741099
Cited by: 237
References: 47
Citations by year: 2026: 5 · 2025: 10 · 2024: 9 · 2023: 9 · 2022: 11 · 2021: 16 · 2020: 13 · 2019: 10 · 2018: 11 · 2017: 11 · 2016: 11 · 2015: 10 · 2014: 17 · 2013: 13 · 2012: 12
FWCI: 0.72
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Current Opinion in Microbiology (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health
National Institute of Allergy and Infectious Diseases (R01 AI/DE 14666)
National Institute of Dental and Craniofacial Research (R01DE014666)
National Center for Research Resources (P41RR011823)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
Health Sciences › Medicine › Epidemiology › Fungal Infections and Studies
Keywords: Candida albicans, morphogenesis, cell cycle progression, polarized growth, hyphal growth, pseudohyphae, yeast cells, Spitzenkörper, polarisome, cyclins, cell cycle checkpoints, fungal pathogens
MeSH terms: Candida albicans, Cell Cycle, Morphogenesis, Protein Kinases, Gene Expression Regulation, Fungal, Cell Polarity, Cell Cycle Proteins, Hyphae

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Morphogenesis and cell cycle progression in Candida albicans

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks