Mechanical Allodynia Circuitry in the Dorsal Horn Is Defined by the Nature of the Injury

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Livak, K. J., & Schmittgen, T. D. (2001) · Methods · doi:10.1006/meth.2001.1262 · Cited by 180,860 · see citing works

Quantitative assessment of tactile allodynia in the rat paw

Chaplan, S. R., Bach, F. W., Pogrel, J. W., Chung, J. M., & Yaksh, T. L. (1994) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(94)90144-9 · Cited by 7,740 · see citing works

Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis

Finnerup, N. B., Attal, N., Haroutounian, S., McNicol, E., Baron, R., Dworkin, R. H., Gilron, I., Haanpää, M., Hansson, P., Jensen, T. S., et al. (2015) · The Lancet Neurology · doi:10.1016/s1474-4422(14)70251-0 · Cited by 3,980 · see citing works

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Kuro-o, M., Matsumura, Y., Aizawa, H., Kawaguchi, H., Suga, T., Utsugi, T., Ohyama, Y., Kurabayashi, M., Kaname, T., Kume, E., et al. (1997) · Nature · doi:10.1038/36285 · Cited by 3,837 · see citing works

Impaired nociception and pain sensation in mice lacking the capsaicin receptor

Caterina, M. J., Leffler, A., Malmberg, A. B., Martin, W. J., Trafton, J., Petersen-Zeitz, K. R., Koltzenburg, M., Basbaum, A. I., & Julius, D. (2000) · Science · doi:10.1126/science.288.5464.306 · Cited by 3,544 · see citing works

Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4)

Bouhassira, D., Attal, N., Alchaar, H., Boureau, F., Brochet, B., Bruxelle, J., Cunin, G., Fermanian, J., Giniès, P., Grun-Overdyking, A., et al. (2005) · Pain · doi:10.1016/j.pain.2004.12.010 · Cited by 2,732 · see citing works

Spared nerve injury: an animal model of persistent peripheral neuropathic pain

Décosterd, I., & Woolf, C. J. (2000) · Pain · doi:10.1016/s0304-3959(00)00276-1 · Cited by 2,317 · see citing works

Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing

Usoskin, D., Furlan, A., Islam, S., Abdo, H., Lönnerberg, P., Lou, D., Hjerling-Leffler, J., Haeggström, J., Kharchenko, O., Kharchenko, P. V., et al. (2015) · Nature Neuroscience · doi:10.1038/nn.3881 · Cited by 2,136 · see citing works

TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents

Bautista, D. M., Jordt, S. E., Nikai, T., Tsuruda, P. R., Read, A. J., Poblete, J., Yamoah, E. N., Basbaum, A. I., & Julius, D. J. (2006) · Cell · doi:10.1016/j.cell.2006.02.023 · Cited by 1,921 · see citing works

Remote Control of Neuronal Activity in Transgenic Mice Expressing Evolved G Protein-Coupled Receptors

Alexander, G. M., Rogan, S. C., Abbas, A. I., Armbruster, B. N., Pei, Y., Allen, J., Nonneman, R. J., Hartmann, J. F., Moy, S. S., Nicolelis, M. A. L., et al. (2009) · Neuron · doi:10.1016/j.neuron.2009.06.014 · Cited by 996 · see citing works

Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli

Cavanaugh, D. J., Lee, H., Lo, L., Shields, S. D., Zylka, M. J., Basbaum, A. I., & Anderson, D. J. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0901507106 · Cited by 706 · see citing works

Preserved Acute Pain and Reduced Neuropathic Pain in Mice Lacking PKCγ

Malmberg, A. B., Chen, C., Tonegawa, S., & Basbaum, A. I. (1997) · Science · doi:10.1126/science.278.5336.279 · Cited by 690 · see citing works

Identification of Spinal Circuits Transmitting and Gating Mechanical Pain

Duan, B., Cheng, L., Bourane, S., Britz, O., Padilla, C., Garcia-Campmany, L., Krashes, M., Knowlton, W., Velasquez, T., Ren, X., et al. (2014) · Cell · doi:10.1016/j.cell.2014.11.003 · Cited by 582 · see citing works

Roles of inflammation, neurogenic inflammation, and neuroinflammation in pain

Matsuda, M., Huh, Y., & Ji, R. (2018) · Journal of Anesthesia · doi:10.1007/s00540-018-2579-4 · Cited by 570 · see citing works

Neural circuits for pain: Recent advances and current views

Peirs, C., & Seal, R. P. (2016) · Science · doi:10.1126/science.aaf8933 · Cited by 481 · see citing works

Neuronal atlas of the dorsal horn defines its architecture and links sensory input to transcriptional cell types

Häring, M., Zeisel, A., Hochgerner, H., Rinwa, P., Jakobsson, J. E. T., Lönnerberg, P., La Manno, G., Sharma, N., Borgius, L., Kiehn, O., et al. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0141-1 · Cited by 470 · see citing works

Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors

Seal, R. P., Wang, X., Guan, Y., Raja, S. N., Woodbury, C. J., Basbaum, A. I., & Edwards, R. H. (2009) · Nature · doi:10.1038/nature08505 · Cited by 465 · see citing works

Differential activity-dependent regulation of the lateral mobilities of AMPA and NMDA receptors

Groc, L., Heine, M., Cognet, L., Brickley, K., Stephenson, F. A., Lounis, B., & Choquet, D. (2004) · Nature Neuroscience · doi:10.1038/nn1270 · Cited by 429 · see citing works

The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn

Abraira, V. E., Kuehn, E. D., Chirila, A. M., Springel, M. W., Toliver, A. A., Zimmerman, A. L., Orefice, L. L., Boyle, K. A., Bai, L., Song, B. J., et al. (2017) · Cell · doi:10.1016/j.cell.2016.12.010 · Cited by 409 · see citing works

Disinhibition Opens the Gate to Pathological Pain Signaling in Superficial Neurokinin 1 Receptor-Expressing Neurons in Rat Spinal Cord

Torsney, C., & MacDermott, A. B. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.4584-05.2006 · Cited by 407 · see citing works

Dorsal Horn Circuits for Persistent Mechanical Pain

Peirs, C., Williams, S.-P. G., Zhao, X., Walsh, C. E., Gedeon, J. Y., Cagle, N. E., Goldring, A. C., Hioki, H., Liu, Z., Marell, P. S., et al. (2015) · Neuron · doi:10.1016/j.neuron.2015.07.029 · Cited by 327 · see citing works

Dorsal Horn Parvalbumin Neurons Are Gate-Keepers of Touch-Evoked Pain after Nerve Injury

Petitjean, H., Pawlowski, S. A., Fraine, S. L., Sharif, B., Hamad, D., Fatima, T., Berg, J., Brown, C. M., Jan, L.-Y., Ribeiro-da-Silva, A., et al. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.09.080 · Cited by 326 · see citing works

Spared nerve injury model of neuropathic pain in the mouse: a behavioral and anatomic analysis

Shields, S. D., Eckert, W. A., & Basbaum, A. I. (2003) · Journal of Pain · doi:10.1067/s1526-5900(03)00781-8 · Cited by 322 · see citing works

Dissecting Local Circuits: Parvalbumin Interneurons Underlie Broad Feedback Control of Olfactory Bulb Output

Miyamichi, K., Shlomai, Y., Shu, M., Weissbourd, B., Luo, L., & Mizrahi, A. (2013) · Neuron · doi:10.1016/j.neuron.2013.08.027 · Cited by 309 · see citing works

Chemical and Genetic Engineering of Selective Ion Channel–Ligand Interactions

Magnus, C. J., Lee, P. H., Atasoy, D., Su, H. H., Looger, L. L., & Sternson, S. M. (2011) · Science · doi:10.1126/science.1206606 · Cited by 296 · see citing works

A feed-forward spinal cord glycinergic neural circuit gates mechanical allodynia

Lü, Y., Dong, H., Gao, Y., Gong, Y., Ren, Y., Gu, N., Zhou, S., Xia, N., Sun, Y., Ji, R., et al. (2013) · Journal of Clinical Investigation · doi:10.1172/jci70026 · Cited by 287 · see citing works

Touch and tactile neuropathic pain sensitivity are set by corticospinal projections

Liu, Y., Latremoliere, A., Li, X., Zhang, Z., Chen, M., Wang, X., Fang, C., Zhu, J., Alexandre, C., Gao, Z., et al. (2018) · Nature · doi:10.1038/s41586-018-0515-2 · Cited by 276 · see citing works

Identifying the pathways required for coping behaviours associated with sustained pain

Huang, T., Lin, S.-H., Malewicz, N. M., Zhang, Y., Zhang, Y., Goulding, M., LaMotte, R. H., & Ma, Q. (2019) · Nature · doi:10.1038/s41586-018-0793-8 · Cited by 264 · see citing works

Identification of spinal circuits involved in touch-evoked dynamic mechanical pain

Cheng, L., Duan, B., Huang, T., Zhang, Y., Chen, Y., Britz, O., Garcia-Campmany, L., Ren, X., Vong, L., Lowell, B. B., et al. (2017) · Nature Neuroscience · doi:10.1038/nn.4549 · Cited by 240 · see citing works

Glycine Inhibitory Dysfunction Turns Touch into Pain through PKCgamma Interneurons

Miraucourt, L. S., Dallel, R., & Voisin, D. L. (2007) · PLoS ONE · doi:10.1371/journal.pone.0001116 · Cited by 208 · see citing works

Identifying functional populations among the interneurons in laminae I-III of the spinal dorsal horn

Todd, A. J. (2017) · Molecular Pain · doi:10.1177/1744806917693003 · Cited by 204 · see citing works

Mechanisms of Incisional Pain

Brennan, T. J., Zahn, P. K., & Pogatzki-Zahn, E. M. (2005) · Anesthesiology Clinics of North America · doi:10.1016/j.atc.2004.11.009 · Cited by 188 · see citing works

Uncovering the Cells and Circuits of Touch in Normal and Pathological Settings

Moehring, F., Halder, P., Seal, R. P., & Stucky, C. L. (2018) · Neuron · doi:10.1016/j.neuron.2018.10.019 · Cited by 155 · see citing works

Leaky Gate Model: Intensity-Dependent Coding of Pain and Itch in the Spinal Cord

Sun, S., Xu, Q., Guo, C., Guan, Y., Liu, Q., & Dong, X. (2017) · Neuron · doi:10.1016/j.neuron.2017.01.012 · Cited by 154 · see citing works

TRPA1 Mediates Mechanical Sensitization in Nociceptors during Inflammation

Lennertz, R. C., Kossyreva, E. A., Smith, A. K., & Stucky, C. L. (2012) · PLoS ONE · doi:10.1371/journal.pone.0043597 · Cited by 152 · see citing works

Recent advances in our understanding of the organization of dorsal horn neuron populations and their contribution to cutaneous mechanical allodynia

Peirs, C., Dallel, R., & Todd, A. J. (2020) · Journal of Neural Transmission · doi:10.1007/s00702-020-02159-1 · Cited by 131 · see citing works

Critical role for Epac1 in inflammatory pain controlled by GRK2-mediated phosphorylation of Epac1

Singhmar, P., Huo, X., Eijkelkamp, N., Berciano, S. R., Baameur, F., Mei, F. C., Zhu, Y., Cheng, X., Hawke, D. H., Mayor, F., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1516036113 · Cited by 129 · see citing works

Stimulation of Deep Somatic Tissue with Capsaicin Produces Long-Lasting Mechanical Allodynia and Heat Hypoalgesia that Depends on Early Activation of the cAMP Pathway

Sluka, K. A. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-13-05687.2002 · Cited by 115 · see citing works

How Gastrin-Releasing Peptide Opens the Spinal Gate for Itch

Pagani, M., Albisetti, G. W., Sivakumar, N., Wildner, H., Santello, M., Johannssen, H. C., & Zeilhofer, H. U. (2019) · Neuron · doi:10.1016/j.neuron.2019.04.022 · Cited by 114 · see citing works

Genetic targeting and physiological features of VGLUT3+ amacrine cells

Grimes, W. N., Seal, R. P., Oesch, N. W., Edwards, R. H., & Diamond, J. S. (2011) · Visual Neuroscience · doi:10.1017/s0952523811000290 · Cited by 110 · see citing works

Identification of Early RET+ Deep Dorsal Spinal Cord Interneurons in Gating Pain

Cui, L., Miao, X., Liang, L., Abdus-Saboor, I., Olson, W., Fleming, M. S., Ma, M., Tao, Y.-X., & Luo, W. (2016) · Neuron · doi:10.1016/j.neuron.2016.07.038 · Cited by 100 · see citing works

A Functional Topographic Map for Spinal Sensorimotor Reflexes

Gatto, G., Bourane, S., Ren, X., Di Costanzo, S., Fenton, P. K., Halder, P., Seal, R. P., & Goulding, M. D. (2021) · Neuron · doi:10.1016/j.neuron.2020.10.003 · Cited by 92 · see citing works

Functional heterogeneity of calretinin‐expressing neurons in the mouse superficial dorsal horn: implications for spinal pain processing

Smith, K. M., Boyle, K. A., Madden, J. F., Dickinson, S. A., Jobling, P., Callister, R. J., Hughes, D. I., & Graham, B. A. (2015) · The Journal of Physiology · doi:10.1113/jp270855 · Cited by 88 · see citing works

Central Nervous System Targets: Inhibitory Interneurons in the Spinal Cord

Hughes, D. I., & Todd, A. J. (2020) · Neurotherapeutics · doi:10.1007/s13311-020-00936-0 · Cited by 88 · see citing works

The Role of Spinal Cholecystokinin in Chronic Pain States

Wiesenfeld‐Hallin, Z., Xu, X., & Hökfelt, T. G. M. (2002) · Pharmacology & Toxicology · doi:10.1034/j.1600-0773.2002.910619.x · Cited by 82 · see citing works

Optogenetic Inhibition of CGRPα Sensory Neurons Reveals Their Distinct Roles in Neuropathic and Incisional Pain

Cowie, A. M., Moehring, F., O’Hara, C. L., & Stucky, C. L. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.3565-17.2018 · Cited by 77 · see citing works

Tlx1 and Tlx3 Coordinate Specification of Dorsal Horn Pain-Modulatory Peptidergic Neurons

Xu, Y., Lopes, C., Qian, Y., Liu, Y., Cheng, L., Goulding, M., Turner, E. E., Lima, D., & Ma, Q. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4126-07.2008 · Cited by 76 · see citing works

Protein Kinase C ϵ and γ: Involvement in Formalin-Induced Nociception in Neonatal Rats

Sweitzer, S. M., Wong, S. M. E., Peters, M. C., Mochly‐Rosen, D., Yeomans, D. C., & Kendig, J. J. (2004) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.103.060350 · Cited by 75 · see citing works

Neuronal diversity in the somatosensory system: bridging the gap between cell type and function

Gatto, G., Smith, K. M., Ross, S. E., & Goulding, M. (2019) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2019.03.002 · Cited by 74 · see citing works

Light touch induces ERK activation in superficial dorsal horn neurons after inflammation: involvement of spinal astrocytes and JNK signaling in touch‐evoked central sensitization and mechanical allodynia

Gao, Y., & Ji, R. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.06946.x · Cited by 64 · see citing works

5-HT2AReceptor-Induced Morphological Reorganization of PKCγ-Expressing Interneurons Gates Inflammatory Mechanical Allodynia in Rat

Alba‐Delgado, C., Mountadem, S., Mermet-Joret, N., Monconduit, L., Dallel, R., Artola, A., & Antri, M. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.1294-18.2018 · Cited by 60 · see citing works

A Putative Relay Circuit Providing Low-Threshold Mechanoreceptive Input to Lamina I Projection Neurons via Vertical Cells in Lamina II of the Rat Dorsal Horn

Yasaka, T., Tiong, S. Y., Polgár, E., Watanabe, M., Kumamoto, E., Riddell, J. S., & Todd, A. J. (2014) · Molecular Pain · doi:10.1186/1744-8069-10-3 · Cited by 59 · see citing works

Calretinin positive neurons form an excitatory amplifier network in the spinal cord dorsal horn

Smith, K. M., Browne, T. J., Davis, O. C., Coyle, A., Boyle, K. A., Watanabe, M., Dickinson, S. A., Iredale, J. A., Gradwell, M. A., Jobling, P., et al. (2019) · eLife · doi:10.7554/elife.49190 · Cited by 57 · see citing works

Neuronal networks and nociceptive processing in the dorsal horn of the spinal cord

Cordero‐Erausquin, M., Inquimbert, P., Schlichter, R., & Hugel, S. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.08.048 · Cited by 54 · see citing works

Transcriptional Profiling of Somatostatin Interneurons in the Spinal Dorsal Horn

Chamessian, A. G., Young, M. N., Qadri, Y. J., Berta, T., Ji, R., & de Ven, T. V. (2018) · Scientific Reports · doi:10.1038/s41598-018-25110-7 · Cited by 54 · see citing works

Recruitment of Spinoparabrachial Neurons by Dorsal Horn Calretinin Neurons

Petitjean, H., Bourojeni, F. B., Tsao, D., Davidova, A., Sotocinal, S. G., Mogil, J. S., Kania, A., & Sharif-Naeini, R. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.07.048 · Cited by 47 · see citing works

Identification of Early RET+ Deep Dorsal Spinal Cord Interneurons in Gating Pain

Cui, L., Miao, X., Liang, L., Abdus-Saboor, I., Olson, W. P., Fleming, M. S., Ma, M., Tao, Y., & Luo, W. (2016) · Neuron · doi:10.1016/j.neuron.2016.09.010 · Cited by 41 · see citing works

Expression of cholecystokinin by neurons in mouse spinal dorsal horn

Gutièrrez‐Mecinas, M., Bell, A. M., Shepherd, F., Polgár, E., Watanabe, M., Furuta, T., & Todd, A. J. (2019) · The Journal of Comparative Neurology · doi:10.1002/cne.24657 · Cited by 41 · see citing works

Expression of Calretinin Among Different Neurochemical Classes of Interneuron in the Superficial Dorsal Horn of the Mouse Spinal Cord

Gutièrrez‐Mecinas, M., Davis, O., Polgár, E., Shahzad, M., Navarro-Batista, K., Furuta, T., Watanabe, M., Hughes, D. I., & Todd, A. J. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.12.009 · Cited by 35 · see citing works

Protein kinase C gamma interneurons in the rat medullary dorsal horn: Distribution and synaptic inputs to these neurons, and subcellular localization of the enzyme

Peirs, C., Patil, S. S., Bouali‐Benazzouz, R., Artola, A., Landry, M., & Dallel, R. (2013) · The Journal of Comparative Neurology · doi:10.1002/cne.23407 · Cited by 33 · see citing works

Subpopulations of PKCγ interneurons within the medullary dorsal horn revealed by electrophysiologic and morphologic approach

Alba‐Delgado, C., Khoueiry, C. E., Peirs, C., Dallel, R., Artola, A., & Antri, M. (2015) · Pain · doi:10.1097/j.pain.0000000000000221 · Cited by 31 · see citing works

Is Optogenetic Activation of Vglut1-Positive Aβ Low-Threshold Mechanoreceptors Sufficient to Induce Tactile Allodynia in Mice after Nerve Injury?

Chamessian, A. G., Matsuda, M., Young, M. N., Wang, M. Y., Zhang, Z., Liu, D., Tobin, B., Xu, Z., de Ven, T. V., & Ji, R. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.2064-18.2019 · Cited by 30 · see citing works

Expression of green fluorescent protein defines a specific population of lamina II excitatory interneurons in the GRP::eGFP mouse

Bell, A. M., Gutierrez-Mecinas, M., Stevenson, A., Casas-Benito, A., Wildner, H., West, S. J., Watanabe, M., & Todd, A. J. (2020) · Scientific Reports · doi:10.1038/s41598-020-69711-7 · Cited by 25 · see citing works

PKCγ interneurons, a gateway to pathological pain in the dorsal horn

Artola, A., Voisin, D. L., & Dallel, R. (2020) · Journal of Neural Transmission · doi:10.1007/s00702-020-02162-6 · Cited by 23 · see citing works

A harmonized atlas of mouse spinal cord cell types and their spatial organization

Russ, D. E., Cross, R. B. P., Li, L., Koch, S. C., Matson, K. J. E., Yadav, A., Alkaslasi, M. R., Lee, D. I., Le Pichon, C. E., Menon, V., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-25125-1 · Cited by 255 · see citing works

Brain circuits for pain and its treatment

Lindsay, N. M., Chen, C., Gilam, G., Mackey, S., & Scherrer, G. (2021) · Science Translational Medicine · doi:10.1126/scitranslmed.abj7360 · Cited by 234 · see citing works

A functional subdivision within the somatosensory system and its implications for pain research

Ma, Q. (2022) · Neuron · doi:10.1016/j.neuron.2021.12.015 · Cited by 109 · see citing works

Mediators of Neuropathic Pain; Focus on Spinal Microglia, CSF-1, BDNF, CCL21, TNF-α, Wnt Ligands, and Interleukin 1β

Boakye, P. A., Tang, S.-J., & Smith, P. A. (2021) · Frontiers in Pain Research · doi:10.3389/fpain.2021.698157 · Cited by 102 · see citing works

Neuroplasticity related to chronic pain and its modulation by microglia

Hiraga, S.-I., Itokazu, T., Nishibe, M., & Yamashita, T. (2022) · Inflammation and Regeneration · doi:10.1186/s41232-022-00199-6 · Cited by 98 · see citing works

A Functional Topographic Map for Spinal Sensorimotor Reflexes

Gatto, G., Bourane, S., Ren, X., Di Costanzo, S., Fenton, P. K., Halder, P., Seal, R. P., & Goulding, M. D. (2021) · Neuron · doi:10.1016/j.neuron.2020.10.003 · Cited by 92 · see citing works

Peripheral Voltage-Gated Cation Channels in Neuropathic Pain and Their Potential as Therapeutic Targets

Alles, S. R. A., & Smith, P. A. (2021) · Frontiers in Pain Research · doi:10.3389/fpain.2021.750583 · Cited by 89 · see citing works

scRNA-sequencing reveals subtype-specific transcriptomic perturbations in DRG neurons of PirtEGFPf mice in neuropathic pain condition

Zhang, C., Hu, M., Wang, X., Cui, X., Liu, J., Huang, Q., Cao, X., Zhou, F., Qian, J. X., He, S.-Q., et al. (2022) · eLife · doi:10.7554/elife.76063 · Cited by 64 · see citing works

Presynaptic Inhibition of Pain and Touch in the Spinal Cord: From Receptors to Circuits

Comitato, A., & Bardoni, R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22010414 · Cited by 57 · see citing works

Spinal cord retinoic acid receptor signaling gates mechanical hypersensitivity in neuropathic pain

Cao, B., Scherrer, G., & Chen, L. (2022) · Neuron · doi:10.1016/j.neuron.2022.09.027 · Cited by 51 · see citing works

Cell type-specific calcium imaging of central sensitization in mouse dorsal horn

Warwick, C. A., Salsovic, J., Hachisuka, J., Smith, K. M., Sheahan, T. D., Chen, H., Ibinson, J. W., Koerber, H. R., & Ross, S. E. (2022) · Nature Communications · doi:10.1038/s41467-022-32608-2 · Cited by 50 · see citing works

Neuropathic pain; what we know and what we should do about it

Smith, P. A. (2023) · Frontiers in Pain Research · doi:10.3389/fpain.2023.1220034 · Cited by 49 · see citing works

Electroacupuncture alleviates mechanical allodynia and anxiety‐like behaviors induced by chronic neuropathic pain via regulating rostral anterior cingulate cortex‐dorsal raphe nucleus neural circuit

Xu, Y., Zhu, X., Chen, Y., Chen, Y., Zhu, Y., Xiao, S., Wu, M., Wang, Y., Zhang, C., Wu, Z., et al. (2023) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14328 · Cited by 47 · see citing works

Spinal neuropeptide Y Y1 receptor-expressing neurons are a pharmacotherapeutic target for the alleviation of neuropathic pain

Nelson, T. S., Sinha, G. P., dos Santos, D. F. D. S., Jukkola, P. I., Prasoon, P., Winter, M. K., McCarson, K. E., Smith, B. N., & Taylor, B. K. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2204515119 · Cited by 48 · see citing works

Multiscale Computer Model of the Spinal Dorsal Horn Reveals Changes in Network Processing Associated with Chronic Pain

Medlock, L., Sekiguchi, K., Hong, S., Durá-Bernal, S., Lytton, W. W., & Prescott, S. A. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.1199-21.2022 · Cited by 41 · see citing works

Glycine Receptors in Spinal Nociceptive Control—An Update

Zeilhofer, H. U., Werynska, K., Gingras, J., & Yévenes, G. E. (2021) · Biomolecules · doi:10.3390/biom11060846 · Cited by 40 · see citing works

Diversity of inhibitory and excitatory parvalbumin interneuron circuits in the dorsal horn

Gradwell, M. A., Boyle, K. A., Browne, T. J., Bell, A. M., Leonardo, J., Reyes, F. S. P., Dickie, A. C., Smith, K. M., Callister, R. J., Dayas, C. V., et al. (2021) · Pain · doi:10.1097/j.pain.0000000000002422 · Cited by 37 · see citing works

Parabrachial Calca neurons drive nociplasticity

Condon, L. F., Yu, Y., Park, S., Cao, F., Pauli, J. L., Nelson, T. S., & Palmiter, R. D. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114057 · Cited by 38 · see citing works

Targeted anatomical and functional identification of antinociceptive and pronociceptive serotonergic neurons that project to the spinal dorsal horn

Ganley, R. P., de Sousa, M. M., Werder, K., Öztürk, T., Mendes, R., Ranucci, M., Wildner, H., & Zeilhofer, H. U. (2023) · eLife · doi:10.7554/elife.78689 · Cited by 31 · see citing works

Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition

Arokiaraj, C. M., Leone, M. J., Kleyman, M., Chamessian, A. G., Noh, M., Phan, B. N., Lopes, B. C., Corrigan, K. A., Cherupally, V. K., Yeramosu, D., et al. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114876 · Cited by 32 · see citing works

Electroacupuncture ameliorates pain in cervical spondylotic radiculopathy rat by inhibiting the CaMKII/CREB/BDNF signaling pathway and regulating spinal synaptic plasticity

Su, H., Chen, H., Zhang, X., Su, S.-Y., Li, J., Guo, Y., Wang, Q., Xie, C., & Yang, P. (2023) · Brain and Behavior · doi:10.1002/brb3.3177 · Cited by 29 · see citing works

A parabrachial hub for need-state control of enduring pain

Goldstein, N., Maes, A., Allen, H. N., Nelson, T. S., Kruger, K. A., Kindel, M., Yeung, A. T. M., Smith, N. K., Carty, J. R. E., Boccia, L., et al. (2025) · Nature · doi:10.1038/s41586-025-09602-x · Cited by 35 · see citing works

Advances and Barriers in Understanding Presynaptic N-Methyl-D-Aspartate Receptors in Spinal Pain Processing

Dedek, A., & Hildebrand, M. E. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.864502 · Cited by 28 · see citing works

Parabrachial neurons promote nociplastic pain

Palmiter, R. D. (2024) · Trends in Neurosciences · doi:10.1016/j.tins.2024.07.002 · Cited by 29 · see citing works

Neuron-specific spinal cord translatomes reveal a neuropeptide code for mouse dorsal horn excitatory neurons

Gupta, R. R. D., Scheurer, L., Pelczar, P., Wildner, H., & Zeilhofer, H. U. (2021) · Scientific Reports · doi:10.1038/s41598-021-84667-y · Cited by 27 · see citing works

Nerve injury disrupts temporal processing in the spinal cord dorsal horn through alterations in PV+ interneurons

Rankin, G., Chirila, A. M., Emanuel, A. J., Zhang, Z., Woolf, C. J., Drugowitsch, J., & Ginty, D. D. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.113718 · Cited by 24 · see citing works

Differential modification of ascending spinal outputs in acute and chronic pain states

Yarmolinsky, D. A., Zeng, X., MacKinnon-Booth, N., Greene, C. A., Kim, C., Cheng, Y., Turnes, B. L., & Woolf, C. J. (2025) · Neuron · doi:10.1016/j.neuron.2025.01.031 · Cited by 24 · see citing works

Ontogeny of the spinal cord dorsal horn

Roome, R. B., Yadav, A., Flores, L., Puarr, A. K., Nardini, D., Richardson, A. J. W., Waclaw, R. R., Arkell, R. M., Menon, V., Johnson, J. E. B., et al. (2026) · Science · doi:10.1126/science.adx5781 · Cited by 22 · see citing works

Morphological and neurochemical characterization of glycinergic neurons in laminae I–IV of the mouse spinal dorsal horn

Miranda, C. O., Hegedűs, K., Wildner, H., Zeilhofer, H. U., & Antal, M. (2021) · The Journal of Comparative Neurology · doi:10.1002/cne.25232 · Cited by 23 · see citing works

Dexmedetomidine alleviates pain in MPTP-treated mice by activating the AMPK/mTOR/NF-κB pathways in astrocytes

Chen, Y. S., Li, Y., Li, C., Zhu, D., Cheng, O., & Cui, J. G. (2022) · Neuroscience Letters · doi:10.1016/j.neulet.2022.136933 · Cited by 23 · see citing works

Targeting the somatosensory system with AAV9 and AAV2retro viral vectors

Skorput, A. G. J., Gore, R., Schorn, R. E., Riedl, M. S., de Velasco, E. M. F., Hadlich, B., Kitto, K. F., Fairbanks, C. A., & Vulchanova, L. (2022) · PLoS ONE · doi:10.1371/journal.pone.0264938 · Cited by 22 · see citing works

Neurochemical atlas of the cat spinal cord

Veshchitskii, A. A., Shkorbatova, P. Y., & Merkulyeva, N. S. (2022) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2022.1034395 · Cited by 22 · see citing works

Interactions Among Non-Coding RNAs and mRNAs in the Trigeminal Ganglion Associated with Neuropathic Pain

Fang, Z., Liao, H.-L., Tang, Q.-F., Liu, Y.-J., Zhang, Y., Lin, J., Yu, H., Zhou, C., Li, C., Liu, F., et al. (2022) · Journal of Pain Research · doi:10.2147/jpr.s382692 · Cited by 21 · see citing works

Spinal VGLUT3 lineage neurons drive visceral mechanical allodynia but not sensitized visceromotor reflexes

Qi, L., Lin, S.-H., & Ma, Q. (2022) · Neuron · doi:10.1016/j.neuron.2022.12.003 · Cited by 21 · see citing works

Alleviation of neuropathic pain with neuropeptide Y requires spinal Npy1r interneurons that coexpress Grp

Nelson, T. S., Allen, H. N., Basu, P., Prasoon, P., Nguyen, E. K., Arokiaraj, C. M., dos Santos, D. F. D. S., Seal, R. P., Ross, S. E., Todd, A. J., et al. (2023) · JCI Insight · doi:10.1172/jci.insight.169554 · Cited by 21 · see citing works

Central control of opioid-induced mechanical hypersensitivity and tolerance in mice

Yin, G., Duan, K., Dong, D., Du, F., Guo, C., Zhang, C., Liu, X., Sun, Y., Huang, T., Cui, G.-F., et al. (2024) · Neuron · doi:10.1016/j.neuron.2024.09.014 · Cited by 20 · see citing works

The structure of sensory afferent compartments in health and disease

Middleton, S. J., Pérez-Sánchez, J., & Dawes, J. M. (2021) · Journal of Anatomy · doi:10.1111/joa.13544 · Cited by 19 · see citing works

Role of C-tactile fibers in pain modulation: animal and human perspectives

Larsson, M., & Nagi, S. S. (2021) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2021.09.005 · Cited by 20 · see citing works

The Known Biology of Neuropathic Pain and Its Relevance to Pain Management

Smith, P. A. (2023) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/cjn.2023.10 · Cited by 20 · see citing works

Ventral Hippocampal CA1 Pyramidal Neurons Encode Nociceptive Information

Wang, Y., Liu, N., Ma, L., Yue, L., Cui, S., Liu, F., Yi, M., & Wan, Y. (2023) · Neuroscience Bulletin · doi:10.1007/s12264-023-01086-x · Cited by 20 · see citing works

Spatial transcriptomics and single-nucleus RNA sequencing reveal a transcriptomic atlas of adult human spinal cord

Zhang, D., Chen, Y., Wei, Y., Chen, H., Wu, Y., Wu, L., Li, J., Ren, Q., Miao, C., Zhu, T., et al. (2024) · eLife · doi:10.7554/elife.92046.2 · Cited by 19 · see citing works

Organic anion transporter 1 is an HDAC4-regulated mediator of nociceptive hypersensitivity in mice

Litke, C., Hagenston, A. M., Kenkel, A.-K., Páldy, E., Lu, J., Kuner, R., & Mauceri, D. (2022) · Nature Communications · doi:10.1038/s41467-022-28357-x · Cited by 18 · see citing works

Endophilin A2 controls touch and mechanical allodynia via kinesin-mediated Piezo2 trafficking

Xie, M.-X., Lai, R.-C., Xiao, Y.-B., Zhang, X., Cao, X.-Y., Tian, X.-Y., Chen, Z., Chen, Z.-Y., Cao, Y., Li, X., et al. (2024) · Military Medical Research · doi:10.1186/s40779-024-00520-z · Cited by 17 · see citing works

Infralimbic-basolateral amygdala circuit associated with depression-like not anxiety-like behaviors induced by chronic neuropathic pain and the antidepressant effects of electroacupuncture

Xie, Y., Shen, Z., Zhu, X., Pan, Y., Sun, H., Xie, M., Gong, Q., Hu, Q., Chen, J., Wu, Z., et al. (2024) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2024.111092 · Cited by 18 · see citing works

Identification of brain-to-spinal circuits controlling the laterality and duration of mechanical allodynia in mice

Huo, J., Du, F., Duan, K., Yin, G., Liu, X., Ma, Q., Dong, D., Sun, M., Hao, M., Su, D., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112300 · Cited by 16 · see citing works

Network model of nociceptive processing in the superficial spinal dorsal horn reveals mechanisms of hyperalgesia, allodynia, and spinal cord stimulation

Gilbert, J. E., Zhang, T. C., Esteller, R., & Grill, W. M. (2023) · Journal of Neurophysiology · doi:10.1152/jn.00186.2023 · Cited by 16 · see citing works

Modulation of Comorbid Chronic Neuropathic Pain and Anxiety-Like Behaviors by Glutamatergic Neurons in the Ventrolateral Periaqueductal Gray and the Analgesic and Anxiolytic Effects of Electroacupuncture

Zhu, X., Zhang, C., Hu, Y., Wang, Y., Xiao, S., Zhu, Y., Sun, H., Sun, J., Xu, C., Xu, Y., et al. (2024) · eNeuro · doi:10.1523/eneuro.0454-23.2024 · Cited by 17 · see citing works

Involvement of basolateral amygdala‐rostral anterior cingulate cortex in mechanical allodynia and anxiety‐like behaviors and potential mechanisms of electroacupuncture

Chen, Y., Tong, S., Xu, Y., Xu, Y., Wu, Z., Zhu, X., Wang, X., Li, C., Lin, C., Li, X., et al. (2024) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.70035 · Cited by 16 · see citing works

The dorsal column nuclei scale mechanical sensitivity in naive and neuropathic pain states

Upadhyay, A., Gradwell, M. A., Vajtay, T. J., Conner, J., Sanyal, A. A., Azadegan, C., Patel, K., Thackray, J. K., Bohic, M., Imai, F., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.115556 · Cited by 15 · see citing works

Transcriptome-wide analysis of trigeminal ganglion and subnucleus caudalis in a mouse model of chronic constriction injury-induced trigeminal neuralgia

Cui, X., Qin, B., Xia, C., Hong Li, A., Li, Z., Li, Z., Nasır, A., & Bai, Q. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1230633 · Cited by 15 · see citing works

Spatial transcriptomics and single-nucleus RNA sequencing reveal a transcriptomic atlas of adult human spinal cord

Zhang, D., Chen, Y., Wei, Y., Chen, H., Wu, Y., Wu, L., Li, J., Ren, Q., Miao, C., Zhu, T., et al. (2023) · eLife · doi:10.7554/elife.92046 · Cited by 14 · see citing works

CCK2 receptors in chronic pain

LaVigne, J. E., & Alles, S. R. A. (2022) · Neurobiology of Pain · doi:10.1016/j.ynpai.2022.100092 · Cited by 15 · see citing works

Spinal CCK1 Receptors Contribute to Somatic Pain Hypersensitivity Induced by Malocclusion via a Reciprocal Neuron-Glial Signaling Cascade

Xiang, T., Li, J., Su, H.-Y., Bai, K.-H., Wang, S., Traub, R. J., & Cao, D. (2022) · Journal of Pain · doi:10.1016/j.jpain.2022.05.009 · Cited by 15 · see citing works

c-Maf-positive spinal cord neurons are critical elements of a dorsal horn circuit for mechanical hypersensitivity in neuropathy

Frezel, N., Ranucci, M., Foster, E., Wende, H., Pelczar, P., Mendes, R., Ganley, R. P., Werynska, K., d‘Aquin, S., Beccarini, C., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112295 · Cited by 13 · see citing works

Contribution of µ Opioid Receptor–expressing Dorsal Horn Interneurons to Neuropathic Pain–like Behavior in Mice

Qi, Y., Nelson, T. S., Prasoon, P., Norris, C., & Taylor, B. K. (2023) · Anesthesiology · doi:10.1097/aln.0000000000004735 · Cited by 12 · see citing works

Differential Neuronal Activation of Nociceptive Pathways in Neuropathic Pain After Spinal Cord Injury

He, Z., Zhang, J., Xu, J. L., Wang, Y., Zheng, X., & Wang, W. (2025) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-025-01532-6 · Cited by 11 · see citing works

A Deep-Learning Driven Investigation of the Circuit Basis for Reflexive Hypersensitivity to Thermal Pain

Reddy, P., Vasudeva, J. S., Shah, D. P., Prajapati, J. N., Harikumar, N., & Barik, A. (2023) · Neuroscience · doi:10.1016/j.neuroscience.2023.08.023 · Cited by 11 · see citing works

Thymus persicus (Ronniger ex Rech. f.) Jalas alleviates nociceptive and neuropathic pain behavior in mice: Multiple mechanisms of action

Abed, D. Z., Sadeghian, R., Mohammadi, S., & Akram, M. (2021) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.114695 · Cited by 11 · see citing works

The T-Type Calcium Channel Cav3.2 in Somatostatin Interneurons in Spinal Dorsal Horn Participates in Mechanosensation and Mechanical Allodynia in Mice

Zhi, Y., Cao, F., Su, X.-J., Shu-wen, G., Zheng, H.-N., Jiang, J., Su, L., Liu, J., Wang, Y., Zhang, Y., et al. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.875726 · Cited by 10 · see citing works

Chronic Pain–Related Jaw Muscle Motor Load and Sensory Processing

Nickel, J. C., Gonzalez, Y. M., Wu, Y. X., Liu, Y., Liu, H., & Iwasaki, L. R. (2022) · Journal of Dental Research · doi:10.1177/00220345221099885 · Cited by 10 · see citing works

Ca2+-Permeable AMPA Receptors Contribute to Changed Dorsal Horn Neuronal Firing and Inflammatory Pain

Kopach, O., Dobropolska, Y., Belan, P. V., & Voitenko, N. V. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032341 · Cited by 10 · see citing works

Intersectional genetic tools to study skilled reaching in mice

Nicola, F., Hua, I., & Levine, A. J. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113879 · Cited by 9 · see citing works

Modality-Specific Modulation of Temperature Representations in the Spinal Cord after Injury

Chen, R., Kamalani, G. N. A., & Chen, X. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.1104-21.2021 · Cited by 9 · see citing works

Long-Term Two-Photon Imaging of Spinal Cord in Freely Behaving MicePreprint

Ju, F., Jian, W., Han, Y., Huang, T., Jin, K., Liu, Z., Cai, S., Liu, N., Wang, L., & Wei, P. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.01.09.475306 · Cited by 9 · see citing works

Enkephalin-mediated modulation of basal somatic sensitivity by regulatory T cells in mice

Aubert, N., Purcarea, M., Novarino, J., Schopp, J., Audibert, A., Li, W., Fornier, M., Cagnet, L., Naturel, M., Casrouge, A., et al. (2024) · eLife · doi:10.7554/elife.91359 · Cited by 8 · see citing works

Z-Guggulsterone Relieves Neuropathic Pain by Inhibiting the Expression of Astrocytes and Proinflammatory Cytokines in the Spinal Dorsal Horn

Dang, S.-J., Wei, W., Li, R.-L., Song, C.-X., & Xu, J. (2022) · Journal of Pain Research · doi:10.2147/jpr.s360126 · Cited by 8 · see citing works

What Is the Role of Dorsal Horn Astrocytes in Chronic Pain and Itch?

Benarroch, E. E. (2022) · Neurology · doi:10.1212/wnl.0000000000201505 · Cited by 8 · see citing works

Targeting Peripheral μ-opioid Receptors or μ-opioid Receptor-Expressing Neurons Does not Prevent Morphine-induced Mechanical Allodynia and Anti-allodynic Tolerance

Du, F., Yin, G., Han, L., Liu, X., Dong, D., Duan, K., Huo, J., Sun, Y., & Cheng, L. (2023) · Neuroscience Bulletin · doi:10.1007/s12264-022-01009-2 · Cited by 8 · see citing works

Suppression of neuropathic pain in the circadian clock–deficient Per2m/m mice involves up-regulation of endocannabinoid system

Yamakawa, W., Yasukochi, S., Tsurudome, Y., Kusunose, N., Yamaguchi, Y., Tsuruta, A., Matsunaga, N., Ushijima, K., Koyanagi, S., & Ohdo, S. (2023) · PNAS Nexus · doi:10.1093/pnasnexus/pgad482 · Cited by 8 · see citing works

Sensory root demyelination: Transforming touch into pain

Ding, Y., & Qi, J. (2021) · Glia · doi:10.1002/glia.24097 · Cited by 8 · see citing works

Selective Involvement of a Subset of Spinal Dorsal Horn Neurons Operated by a Prodynorphin Promoter in Aβ Fiber-Mediated Neuropathic Allodynia-Like Behavioral Responses in Rats

Ishibashi, T., Yoshikawa, Y., Sueto, D., Tashima, R., Tozaki‐Saitoh, H., Koga, K., Yamaura, K., & Tsuda, M. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.911122 · Cited by 7 · see citing works

Synaptic Targets of Glycinergic Neurons in Laminae I–III of the Spinal Dorsal Horn

Miranda, C. O., Hegedűs, K., Kis, G. N., & Antal, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24086943 · Cited by 8 · see citing works

Fast-conducting mechanonociceptors uniquely engage reflexive and affective pain circuitry to drive protective responses

Lezgiyeva, K., Liu, J., Nguyen, K., DeLisle, M. M., Ko, F. C., Fullam, S., Obeidat, A. M., Turecek, J., Alkislar, I., Lehnert, B. P., et al. (2026) · Neuron · doi:10.1016/j.neuron.2026.06.014 · Cited by 7 · see citing works

Hypothalamic A11 Nuclei Regulate the Circadian Rhythm of Spinal Mechanonociception through Dopamine Receptors and Clock Gene Expression

Piña-Leyva, C., Lara-Lozano, M., Rodríguez-Sánchez, M., Vidal‐Cantú, G. C., Zavalza, E. B., Jiménez‐Estrada, I., Delgado‐Lezama, R., Rodríguez‐Sosa, L., Granados‐Soto, V., González-Barrios, J. A., et al. (2022) · Life · doi:10.3390/life12091411 · Cited by 8 · see citing works

lncRNA IL-17RA-1 Attenuates LPS-Induced Sepsis via miR-7847-3p/PRKCG-Mediated MAPK Signaling Pathway

Gan, Y., Long, J., Zeng, Y., Zhang, Y., & Tao, Y. (2022) · Mediators of Inflammation · doi:10.1155/2022/9923204 · Cited by 7 · see citing works

Spinal glycinergic currents are reduced in a rat model of neuropathic pain following partial nerve ligation but not chronic constriction injury

Natale, C. A., Christie, M. J., & Aubrey, K. R. (2022) · Journal of Neurophysiology · doi:10.1152/jn.00451.2022 · Cited by 7 · see citing works

Mechanisms for dysregulation of excitatory-inhibitory balance underlying allodynia in dorsal horn neural subcircuits

Ginsberg, A. G., Lempka, S. F., Duan, B., Booth, V., & Crodelle, J. A. (2025) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1012234 · Cited by 6 · see citing works

The Circadian Clock Component REV-ERB Is an Analgesic Target for Cancer-Induced Tactile Pain Hypersensitivity

Yasukochi, S., Yamakawa, W., Taniguchi, M., Itoyama, S., Tsuruta, A., Kusunose, N., Yamauchi, T., Nakamura, R., Matsunaga, N., Ohdo, S., et al. (2025) · Journal of Neuroscience · doi:10.1523/jneurosci.1969-24.2025 · Cited by 6 · see citing works

The Kv4.3 channel on c-low threshold mechanoreceptors in DRG is a key mediator transforming tactile stimuli into nociceptive signals in chemotherapy-induced neuropathy

Zhang, J., Wang, X., Liu, X., Li, J., Qiao, K., Sun, J., Zuo, J., Zhao, W., He, T., Li, X., et al. (2025) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2025.12.005 · Cited by 6 · see citing works

Pre-Synaptic GABAA in NaV1.8+ Primary Afferents Is Required for the Development of Punctate but Not Dynamic Mechanical Allodynia following CFA Inflammation

Liu, S., Bonalume, V., Gao, Q., Chen, J. T.-C., Rohr, K., Hu, J., & Carr, R. W. (2022) · Cells · doi:10.3390/cells11152390 · Cited by 6 · see citing works

Frequency-Dependent Neural Modulation of Dorsal Horn Neurons by Kilohertz Spinal Cord Stimulation in Rats

Wang, D., Lee, K. Y., KAGAN, Z. B., Bradley, K., & Lee, D. (2024) · Biomedicines · doi:10.3390/biomedicines12061346 · Cited by 6 · see citing works

Translational control in the spinal cord regulates gene expression and pain hypersensitivity in the chronic phase of neuropathic pain

Lister, K. C., Wong, C., Uttam, S., Parisien, M., Stecum, P., Brown, N., Cai, W., Ho-Tieng, D., Hooshmandi, M., Gu, N., et al. (2026) · eLife · doi:10.7554/elife.100451.3 · Cited by 6 · see citing works

Targeting spinal mechanistic target of rapamycin complex 2 alleviates inflammatory and neuropathic pain

Wong, C., Rodriguez-Hernandez, L. D., Lister, K. C., Gu, N., Cai, W., Hooshmandi, M., Fan, J., Brown, N., Nguyen, V., Ribeiro‐da‐Silva, A., et al. (2024) · Brain · doi:10.1093/brain/awae275 · Cited by 6 · see citing works

Protein phosphatase 2Cm-regulated branched-chain amino acid catabolic defect in dorsal root ganglion neurons drives pain sensitization

Lian, N., Li, F., Zhou, C., Yin, Y., Kang, Y., Luo, K., Lui, S., Li, T., & Lu, P. (2024) · Acta Neuropathologica Communications · doi:10.1186/s40478-024-01856-2 · Cited by 6 · see citing works

Persistent, neuropathic-like trigeminal pain after dental implant loading

Ndiaw, A., Braud, A., & Boucher, Y. (2022) · Journal of Clinical and Experimental Dentistry · doi:10.4317/jced.59248 · Cited by 6 · see citing works

Spinal cord microglia drive sex differences in ethanol-mediated PGE2-induced allodynia

Alexander, S. N., Reed, O. A., & Burton, M. D. (2024) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2024.08.026 · Cited by 6 · see citing works

Microglial Depletion does not Affect the Laterality of Mechanical Allodynia in Mice

Ma, Q., Su, D., Huo, J., Yin, G., Dong, D., Duan, K., Hong, C., Xu, H., Ma, J., Liu, D., et al. (2023) · Neuroscience Bulletin · doi:10.1007/s12264-022-01017-2 · Cited by 5 · see citing works

Distinct expression profile reveals glia involvement in the trigeminal system attributing to post-traumatic headache

Nagarajan, G., & Zhang, Y. (2024) · The Journal of Headache and Pain · doi:10.1186/s10194-024-01897-x · Cited by 5 · see citing works

From nociception in aneural animals to human suffering: toward a comparative biology of pain

Walters, E. T. (2025) · Journal of Experimental Biology · doi:10.1242/jeb.251210 · Cited by 7 · see citing works

ACVR1 drives neuropathic pain by regulating NLRP3-Induced neuronal pyroptosis through the p38 and Smad1/5/8 pathways

Zhang, X., Miao, Y., Li, Z., Xu, H., & Niu, Z. (2025) · Neuropharmacology · doi:10.1016/j.neuropharm.2025.110469 · Cited by 5 · see citing works

Neurobiological mechanisms of central sensitisation underlying chronic pain states

Poisbeau, P., & Salvat, É. (2025) · BJA Education · doi:10.1016/j.bjae.2025.06.005 · Cited by 4 · see citing works

Astrocytic Kir4.1 ion channel deficit drives persistent inflammatory facial pain in males

Mountadem, S., Hérault, K., Peirs, C., Borges, G. D. S., Voisin, D. L., Antri, M., & Dallel, R. (2025) · Brain · doi:10.1093/brain/awaf122 · Cited by 4 · see citing works

High frequency alternating current neurostimulation decreases nocifensive behavior in a disc herniation model of lumbar radiculopathy

Dewberry, L. S., Porche, K. M., Koenig, T., Allen, K. D., & Otto, K. J. (2023) · Bioelectronic Medicine · doi:10.1186/s42234-023-00119-0 · Cited by 4 · see citing works

An improved conflict avoidance assay reveals modality-specific differences in pain hypersensitivity across sexes

Ferland, S., Wang, F., Koninck, Y. D., & Ferrini, F. (2024) · Pain · doi:10.1097/j.pain.0000000000003132 · Cited by 4 · see citing works

A novel Nav1.8-FLPo driver mouse for intersectional genetics to uncover the functional significance of primary sensory neuron diversity

Malapert, P., Robert, G., Brunet, E., Chemin, J., Bourinet, E., & Moqrich, A. (2024) · iScience · doi:10.1016/j.isci.2024.109396 · Cited by 4 · see citing works

Sensory Symphonies: How Excitatory Spinal Cord Modules Orchestrate Behavior

Gradwell, M. A., & Abraira, V. E. (2021) · Neuron · doi:10.1016/j.neuron.2020.12.012 · Cited by 4 · see citing works

Distribution of Calretinin-Immunopositive Neurons in the Cat Lumbar Spinal Cord

Veshchitskii, A. A., Евгеньевич, М. П., & Merkulyeva, N. S. (2021) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s0022093021040074 · Cited by 4 · see citing works

Effects of Corticosterone on the Excitability of Glutamatergic and GABAergic Neurons of the Adolescent Mouse Superficial Dorsal Horn

Harbour, K., Cappel, Z., & Baccei, M. L. (2023) · Neuroscience · doi:10.1016/j.neuroscience.2023.07.009 · Cited by 5 · see citing works

Combining Machine Learning and Multiplexed, In Situ Profiling to Engineer Cell Type and Behavioral SpecificityPreprint

Leone, M. J., van de Weerd, R., Brown, A. R., Noh, M., Phan, B. N., Wang, A. Z., Corrigan, K. A., Yeramosu, D., Sestili, H. H., Arokiaraj, C. M., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.06.20.660790 · Cited by 4 · see citing works

Neuropathic Pain-Like Responses in a Chronic CNS Injury Model Are Mediated by Corticospinal-Targeted Spinal Interneurons

Guan, X., Zhu, Y., Zhong, J., & Hollis, E. R., II (2025) · Journal of Neuroscience · doi:10.1523/jneurosci.1264-24.2025 · Cited by 3 · see citing works

Dorsal Horn Circuits for Persistent Mechanical Pain

Peirs, C., Williams, S.-P. G., Zhao, X., Walsh, C. E., Gedeon, J. Y., Cagle, N. E., Goldring, A. C., Hioki, H., Liu, Z., Marell, P. S., et al. (2015) · Neuron · doi:10.1016/j.neuron.2015.07.029 · Cited by 327 · see citing works

Unravelling Spinal Circuits of Pain and Mechanical Allodynia

Gangadharan, V., & Kuner, R. (2015) · Neuron · doi:10.1016/j.neuron.2015.08.013 · Cited by 14 · see citing works

Unmyelinated Low Threshold Mechanoreceptors are Required for Injury-induced Mechanical Hypersensitivity

Seal, R. P., Wang, X., Guan, Y., Raja, S. N., Woodbury, C. J., Basbaum, A. I., & Edwards, R. H. (2016)

Understanding dorsal horn circuits mediating mechanical allodynia

Peirs, C. (2022) · HAL

Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors

Seal, R. P., Wang, X., Guan, Y., Raja, S. N., Woodbury, C. J., Basbaum, A. I., & Edwards, R. H. (2009) · Nature · doi:10.1038/nature08505 · Cited by 465 · see citing works