Dorsal Horn Parvalbumin Neurons Are Gate-Keepers of Touch-Evoked Pain after Nerve Injury

BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain

Coull, J. A. M., Beggs, S., Boudreau, D., Boivin, D., Tsuda, M., Inoue, K., Gravel, C., Salter, M. W., & De Koninck, Y. (2005) · Nature · doi:10.1038/nature04223 · Cited by 1,965 · see citing works

Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain

Coull, J. A. M., Boudreau, D., Bachand, K., Prescott, S. A., Nault, F., Attila Gabor, S. I. K., Koninck, P. D., & Koninck, Y. D. (2003) · Nature · doi:10.1038/nature01868 · Cited by 1,118 · see citing works

Remote Control of Neuronal Activity in Transgenic Mice Expressing Evolved G Protein-Coupled Receptors

Alexander, G. M., Rogan, S. C., Abbas, A. I., Armbruster, B. N., Pei, Y., Allen, J., Nonneman, R. J., Hartmann, J. F., Moy, S. S., Nicolelis, M. A. L., et al. (2009) · Neuron · doi:10.1016/j.neuron.2009.06.014 · Cited by 996 · see citing works

Partial Peripheral Nerve Injury Promotes a Selective Loss of GABAergic Inhibition in the Superficial Dorsal Horn of the Spinal Cord

Moore, K. A., Kohno, T., Karchewski, L. A., Scholz, J., Baba, H., & Woolf, C. J. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-15-06724.2002 · Cited by 859 · see citing works

Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents

Ernfors, P., Lee, K., Kučera, J., & Jaenisch, R. (1994) · Cell · doi:10.1016/0092-8674(94)90213-5 · Cited by 805 · see citing works

Preserved Acute Pain and Reduced Neuropathic Pain in Mice Lacking PKCγ

Malmberg, A. B., Chen, C., Tonegawa, S., & Basbaum, A. I. (1997) · Science · doi:10.1126/science.278.5336.279 · Cited by 690 · see citing works

Identification of Spinal Circuits Transmitting and Gating Mechanical Pain

Duan, B., Cheng, L., Bourane, S., Britz, O., Padilla, C., Garcia-Campmany, L., Krashes, M., Knowlton, W., Velasquez, T., Ren, X., et al. (2014) · Cell · doi:10.1016/j.cell.2014.11.003 · Cited by 582 · see citing works

The impact of neuropathic pain on health-related quality of life

Jensen, M. P., Chodroff, M. J., & Dworkin, R. H. (2007) · Neurology · doi:10.1212/01.wnl.0000259085.61898.9e · Cited by 575 · see citing works

<i>Trpv1</i> Reporter Mice Reveal Highly Restricted Brain Distribution and Functional Expression in Arteriolar Smooth Muscle Cells

Cavanaugh, D. J., Chesler, A. T., Jackson, A. C., Sigal, Y. M., Yamanaka, H., Grant, R., O'Donnell, D., Nicoll, R. A., Shah, N. M., Julius, D., et al. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.6451-10.2011 · Cited by 542 · see citing works

Calcium-binding protein parvalbumin as a neuronal marker

Celio, M. R., & Heizmann, C. W. (1981) · Nature · doi:10.1038/293300a0 · Cited by 486 · see citing works

Transmitting Pain and Itch Messages: A Contemporary View of the Spinal Cord Circuits that Generate Gate Control

Braz, J. M., Solórzano, C., Wang, X., & Basbaum, A. I. (2014) · Neuron · doi:10.1016/j.neuron.2014.01.018 · Cited by 446 · see citing works

Blocking Caspase Activity Prevents Transsynaptic Neuronal Apoptosis and the Loss of Inhibition in Lamina II of the Dorsal Horn after Peripheral Nerve Injury

Scholz, J., Broom, D. C., Youn, D. H., Mills, C. D., Kohno, T., Suter, M. R., Moore, K. A., Décosterd, I., Coggeshall, R. E., & Woolf, C. J. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.1526-05.2005 · Cited by 437 · see citing works

Protein kinase C modulates NMDA receptor trafficking and gating

Lan, J.-Y., Skeberdis, V. A., Jover, T., Grooms, S. Y., Lin, Y., Araneda, R. C., Zheng, X., Bennett, M. V. L., & Zukin, R. S. (2001) · Nature Neuroscience · doi:10.1038/86028 · Cited by 421 · see citing works

Ribosome–Inactivating Proteins from Plants: Present Status and Future Prospects

Stirpe, F., Barbieri, L. L., Battelli, M. G., Soria, M. R., & Lappi, D. A. (1992) · Nature Biotechnology · doi:10.1038/nbt0492-405 · Cited by 410 · see citing works

Disinhibition Opens the Gate to Pathological Pain Signaling in Superficial Neurokinin 1 Receptor-Expressing Neurons in Rat Spinal Cord

Torsney, C., & MacDermott, A. B. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.4584-05.2006 · Cited by 407 · see citing works

Dynorphin Acts as a Neuromodulator to Inhibit Itch in the Dorsal Horn of the Spinal Cord

Kardon, A. P., Polgár, E., Hachisuka, J., Snyder, L. M., Cameron, D., Savage, S., Cai, X., Karnup, S., Fan, C. R., Hemenway, G. M., et al. (2014) · Neuron · doi:10.1016/j.neuron.2014.02.046 · Cited by 369 · see citing works

Targeted Ablation, Silencing, and Activation Establish Glycinergic Dorsal Horn Neurons as Key Components of a Spinal Gate for Pain and Itch

Foster, E., Wildner, H., Tudeau, L., Haueter, S., Ralvenius, W. T., Jegen, M., Johannssen, H. C., Hösli, L., Haenraets, K., Ghanem, A., et al. (2015) · Neuron · doi:10.1016/j.neuron.2015.02.028 · Cited by 350 · see citing works

Remote Control of Neuronal Signaling

Rogan, S. C., & Roth, B. L. (2011) · Pharmacological Reviews · doi:10.1124/pr.110.003020 · Cited by 339 · see citing works

Dorsal Horn Circuits for Persistent Mechanical Pain

Peirs, C., Williams, S.-P. G., Zhao, X., Walsh, C. E., Gedeon, J. Y., Cagle, N. E., Goldring, A. C., Hioki, H., Liu, Z., Marell, P. S., et al. (2015) · Neuron · doi:10.1016/j.neuron.2015.07.029 · Cited by 327 · see citing works

Spared nerve injury model of neuropathic pain in the mouse: a behavioral and anatomic analysis

Shields, S. D., Eckert, W. A., & Basbaum, A. I. (2003) · Journal of Pain · doi:10.1067/s1526-5900(03)00781-8 · Cited by 322 · see citing works

A feed-forward spinal cord glycinergic neural circuit gates mechanical allodynia

Lü, Y., Dong, H., Gao, Y., Gong, Y., Ren, Y., Gu, N., Zhou, S., Xia, N., Sun, Y., Ji, R., et al. (2013) · Journal of Clinical Investigation · doi:10.1172/jci70026 · Cited by 287 · see citing works

GABA decreases in the spinal cord dorsal horn after peripheral neurectomy

Castro‐Lopes, J. M., Tavares, I., & Coimbra, A. (1993) · Brain Research · doi:10.1016/0006-8993(93)90167-l · Cited by 266 · see citing works

Restriction of Transient Receptor Potential Vanilloid-1 to the Peptidergic Subset of Primary Afferent Neurons Follows Its Developmental Downregulation in Nonpeptidergic Neurons

Cavanaugh, D. J., Chesler, A. T., Braz, J. M., Shah, N. M., Julius, D. J., & Basbaum, A. I. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.1299-11.2011 · Cited by 263 · see citing works

Normal and abnormal coding of somatosensory stimuli causing pain

Prescott, S. A., Ma, Q., & De Koninck, Y. (2014) · Nature Neuroscience · doi:10.1038/nn.3629 · Cited by 210 · see citing works

Glycine Inhibitory Dysfunction Turns Touch into Pain through PKCgamma Interneurons

Miraucourt, L. S., Dallel, R., & Voisin, D. L. (2007) · PLoS ONE · doi:10.1371/journal.pone.0001116 · Cited by 208 · see citing works

D5 Dopamine Receptors Enhance Zn2+-Sensitive GABAA Currents in Striatal Cholinergic Interneurons through a PKA/PP1 Cascade

Yan, Z., & Surmeier, D. J. (1997) · Neuron · doi:10.1016/s0896-6273(00)80402-x · Cited by 195 · see citing works

Subpopulations of gabaergic neurons in laminae i–iii of rat spinal dorsal horn defined by coexistence with classical transmitters, peptides, nitric oxide synthase or parvalbumin

Laing, I., Todd, A. J., Heizmann, C. W., & Schmidt, H. H. H. W. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90065-5 · Cited by 177 · see citing works

Innocuous, Not Noxious, Input Activates PKCγ Interneurons of the Spinal Dorsal Horn via Myelinated Afferent Fibers

Neumann, S., Braz, J. M., Skinner, K., Llewellyn‐Smith, I. J., & Basbaum, A. I. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1259-08.2008 · Cited by 175 · see citing works

Lack of evidence for significant neuronal loss in laminae I–III of the spinal dorsal horn of the rat in the chronic constriction injury model

Polgár, E., Gray, S., Riddell, J. S., & Todd, A. J. (2004) · Pain · doi:10.1016/j.pain.2004.06.011 · Cited by 159 · see citing works

Calcium‐binding proteins, parvalbumin‐ and calbindin‐D 28k‐immunoreactive neurons in the rat spinal cord and dorsal root ganglia: A light and electron microscopic study

Antal, M., Freund, T. F., & Polgár, E. (1990) · The Journal of Comparative Neurology · doi:10.1002/cne.902950310 · Cited by 156 · see citing works

Morphological, neurochemical and electrophysiological features of parvalbumin‐expressing cells: a likely source of axo‐axonic inputs in the mouse spinal dorsal horn

Hughes, D. I., Sikander, S., Kinnon, C. M., Boyle, K. A., Watanabe, M., Callister, R. J., & Graham, B. A. (2012) · The Journal of Physiology · doi:10.1113/jphysiol.2012.235655 · Cited by 151 · see citing works

Release of BDNF and GABA in the dorsal horn of neuropathic rats

Lever, I. J., Cunningham, J. R., Grist, J., Yip, P. K., & Malcangio, M. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02848.x · Cited by 145 · see citing works

Different populations of parvalbumin‐ and calbindin‐D28k‐immunoreactive neurons contain GABA and accumulate 3 H‐D‐aspartate in the dorsal horn of the rat spinal cord

Antal, M., Polgár, E., Chalmers, J. P., Minson, J. B., Llewellyn‐Smith, I. J., Heizmann, C. W., & Somogyi, P. (1991) · The Journal of Comparative Neurology · doi:10.1002/cne.903140111 · Cited by 143 · see citing works

Directed molecular evolution of DREADDs: a generic approach to creating next-generation RASSLs

Dong, S., Rogan, S. C., & Roth, B. L. (2010) · Nature Protocols · doi:10.1038/nprot.2009.239 · Cited by 140 · see citing works

Glycine Inhibitory Dysfunction Induces a Selectively Dynamic, Morphine-Resistant, and Neurokinin 1 Receptor- Independent Mechanical Allodynia

Miraucourt, L. S., Moisset, X., Dallel, R., & Voisin, D. L. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.3923-08.2009 · Cited by 121 · see citing works

How the 'slow' Ca2+ buffer parvalbumin affects transmitter release in nanodomain-coupling regimes

Eggermann, E., & Jonas, P. (2012) · Nature Neuroscience · doi:10.1038/nn.3002 · Cited by 119 · see citing works

PSD-95 and PKC converge in regulating NMDA receptor trafficking and gating

Lin, Y., Jover‐Mengual, T., Wong, J., Bennett, M. V. L., & Zukin, R. S. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0609924104 · Cited by 118 · see citing works

Differential Maturation of GABA Action and Anion Reversal Potential in Spinal Lamina I Neurons: Impact of Chloride Extrusion Capacity

Cordero‐Erausquin, M., Coull, J. A. M., Boudreau, D., Rolland, M., & Koninck, Y. D. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.1488-05.2005 · Cited by 117 · see citing works

Mapping sensory circuits by anterograde trans-synaptic transfer of recombinant rabies virus

Zampieri, N., Jessell, T., & Murray, A. J. (2014) · Neuron · doi:10.1016/j.neuron.2013.12.033 · Cited by 106 · see citing works

Tactile allodynia can occur in the spared nerve injury model in the rat without selective loss of GABA or GABAA receptors from synapses in laminae I–II of the ipsilateral spinal dorsal horn

Polgár, E., & Todd, A. J. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.07.009 · Cited by 95 · see citing works

Functional differences between neurochemically defined populations of inhibitory interneurons in the rat spinal dorsal horn

Polgár, E., Sardella, T. C. P., Tiong, S. Y. X., Locke, S., Watanabe, M., & Todd, A. J. (2013) · Pain · doi:10.1016/j.pain.2013.05.001 · Cited by 93 · see citing works

Glycinergic and GABAergic tonic inhibition fine tune inhibitory control in regionally distinct subpopulations of dorsal horn neurons

Takazawa, T., & MacDermott, A. B. (2010) · The Journal of Physiology · doi:10.1113/jphysiol.2010.188292 · Cited by 87 · see citing works

Developing analgesics by enhancing spinal inhibition after injury: GABAA receptor subtypes as novel targets

Munro, G., Ahring, P. K., & Mirza, N. R. (2009) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2009.06.004 · Cited by 77 · see citing works

Recent Progress in Research on Ribosome Inactivating Proteins

Ng, T., Wong, J. H., & Wang, H. (2010) · Current Protein and Peptide Science · doi:10.2174/138920310790274662 · Cited by 76 · see citing works

A spinal analog of memory reconsolidation enables reversal of hyperalgesia

Bonin, R. P., & Koninck, Y. D. (2014) · Nature Neuroscience · doi:10.1038/nn.3758 · Cited by 72 · see citing works

Impaired Excitatory Drive to Spinal Gabaergic Neurons of Neuropathic Mice

Leitner, J., Westerholz, S., Heinke, B., Forsthuber, L., Wunderbaldinger, G., Jäger, T., Gruber-Schoffnegger, D., Braun, K., & Sandkühler, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0073370 · Cited by 68 · see citing works

Parvalbumin- and calbindin D28k-immunoreactive neurons in the superficial layers of the spinal cord dorsal horn of rat

Yamamoto, T., Carr, P. A., Baimbridge, K. G., & Nagy, J. I. (1989) · Brain Research Bulletin · doi:10.1016/0361-9230(89)90195-0 · Cited by 63 · see citing works

Galanin-Immunoreactivity Identifies a Distinct Population of Inhibitory Interneurons in Laminae I-III of the Rat Spinal Cord

Tiong, S. Y., Polgár, E., van Kralingen, J. C., Watanabe, M., & Todd, A. J. (2011) · Molecular Pain · doi:10.1186/1744-8069-7-36 · Cited by 62 · see citing works

HCN4 subunit expression in fast-spiking interneurons of the rat spinal cord and hippocampus

Hughes, D. I., Boyle, K. A., Kinnon, C. M., Bilsland, C., Quayle, J. A., Callister, R. J., & Graham, B. A. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.01.028 · Cited by 55 · see citing works

Cognitive impairment and transmitter‐specific pre‐ and postsynaptic changes in the rat cerebral cortex during ageing

Majdi, M., Ribeiro‐da‐Silva, A., & Cuello, A. C. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05966.x · Cited by 42 · see citing works

Hoxb8 Intersection Defines a Role forLmx1bin Excitatory Dorsal Horn Neuron Development, Spinofugal Connectivity, and Nociception

Szabo, N. E., da Silva, R. V., Sotocinal, S. G., Zeilhofer, H. U., Mogil, J. S., & Kania, A. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.4690-14.2015 · Cited by 39 · see citing works

Ethanol Withdrawal–Associated Allodynia and Hyperalgesia: Age-Dependent Regulation by Protein Kinase Cϵ and γ Ιsozymes

Shumilla, J. A., Liron, T., Mochly-Rosen, D., Kendig, J. J., & Sweitzer, S. M. (2005) · The Journal of Pain · doi:10.1016/j.jpain.2005.03.005 · Cited by 38 · see citing works

Somatic calcium level reports integrated spiking activity of cerebellar interneurons in vitro and in vivo

Franconville, R., Revet, G., Astorga, G., Schwaller, B., & Llano, I. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00133.2011 · Cited by 35 · see citing works

Protein kinase C gamma interneurons in the rat medullary dorsal horn: Distribution and synaptic inputs to these neurons, and subcellular localization of the enzyme

Peirs, C., Patil, S. S., Bouali‐Benazzouz, R., Artola, A., Landry, M., & Dallel, R. (2013) · The Journal of Comparative Neurology · doi:10.1002/cne.23407 · Cited by 33 · see citing works

Control of Neuronal Excitability by Calcium Binding Proteins: A New Mathematical Model for Striatal Fast-Spiking Interneurons

Bischop, D. P., Orduz, D., Lambot, L., Schiffmann, S. N., & Gall, D. (2012) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2012.00078 · Cited by 31 · see citing works

Protein kinase Cγ mediates ethanol withdrawal hyper‐responsiveness of NMDA receptor currents in spinal cord motor neurons

Li, H., Mochly‐Rosen, D., & Kendig, J. J. (2005) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0706033 · Cited by 29 · see citing works

Neurochemical properties of enkephalinergic neurons in lumbar spinal dorsal horn revealed by preproenkephalin–green fluorescent protein transgenic mice

Huang, J. H., Chen, J., Wang, W., Wang, W., Koshimizu, Y., Wei, Y., Kaneko, T., Li, Y., & Wu, S. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.06715.x · Cited by 27 · see citing works

Excitatory Roles of Protein Kinase C in Striatal Cholinergic Interneurons

Deng, P., Pang, Z. P., Lei, Z., & Xu, Z. C. (2009) · Journal of Neurophysiology · doi:10.1152/jn.00325.2009 · Cited by 18 · see citing works

Neuropathic Pain: From Mechanisms to Treatment

Finnerup, N. B., Kuner, R., & Jensen, T. S. (2020) · Physiological Reviews · doi:10.1152/physrev.00045.2019 · Cited by 1,628 · see citing works

Microglia in neuropathic pain: cellular and molecular mechanisms and therapeutic potential

Inoue, K., & Tsuda, M. (2018) · Nature Reviews Neuroscience · doi:10.1038/nrn.2018.2 · Cited by 908 · see citing works

Neural circuits for pain: Recent advances and current views

Peirs, C., & Seal, R. P. (2016) · Science · doi:10.1126/science.aaf8933 · Cited by 481 · see citing works

Neuronal atlas of the dorsal horn defines its architecture and links sensory input to transcriptional cell types

Häring, M., Zeisel, A., Hochgerner, H., Rinwa, P., Jakobsson, J. E. T., Lönnerberg, P., La Manno, G., Sharma, N., Borgius, L., Kiehn, O., et al. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0141-1 · Cited by 470 · see citing works

The connectome of an insect brain

Winding, M., Pedigo, B. D., Barnes, C. L., Patsolic, H. G., Park, Y., Kazimiers, T., Fushiki, A., Andrade, I. V., Khandelwal, A., Valdes-Aleman, J., et al. (2023) · Science · doi:10.1126/science.add9330 · Cited by 435 · see citing works

A Brainstem-Spinal Cord Inhibitory Circuit for Mechanical Pain Modulation by GABA and Enkephalins

François, A., Low, S. A., Sypek, E. I., Christensen, A. J., Sotoudeh, C., Beier, K. T., Ramakrishnan, C., Ritola, K., Sharif‐Naeini, R., Deisseroth, K. A., et al. (2017) · Neuron · doi:10.1016/j.neuron.2017.01.008 · Cited by 354 · see citing works

Circuit dissection of the role of somatostatin in itch and pain

Huang, J., Polgár, E., Solinski, H. J., Mishra, S. K., Tseng, P.-Y., Iwagaki, N., Boyle, K. A., Dickie, A. C., Kriegbaum, M. C., Wildner, H., et al. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0119-z · Cited by 257 · see citing works

A harmonized atlas of mouse spinal cord cell types and their spatial organization

Russ, D. E., Cross, R. B. P., Li, L., Koch, S. C., Matson, K. J. E., Yadav, A., Alkaslasi, M. R., Lee, D. I., Le Pichon, C. E., Menon, V., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-25125-1 · Cited by 255 · see citing works

Spinal Circuits for Touch, Pain, and Itch

Koch, S. C., Acton, D. G., & Goulding, M. (2017) · Annual Review of Physiology · doi:10.1146/annurev-physiol-022516-034303 · Cited by 248 · see citing works

Identification of spinal circuits involved in touch-evoked dynamic mechanical pain

Cheng, L., Duan, B., Huang, T., Zhang, Y., Chen, Y., Britz, O., Garcia-Campmany, L., Ren, X., Vong, L., Lowell, B. B., et al. (2017) · Nature Neuroscience · doi:10.1038/nn.4549 · Cited by 240 · see citing works

A cellular taxonomy of the adult human spinal cord

Yadav, A., Matson, K. J. E., Li, L., Hua, I., Petrescu, J., Kang, K., Alkaslasi, M. R., Lee, D. I., Hasan, S., Galuta, A., et al. (2023) · Neuron · doi:10.1016/j.neuron.2023.01.007 · Cited by 212 · see citing works

Identifying functional populations among the interneurons in laminae I-III of the spinal dorsal horn

Todd, A. J. (2017) · Molecular Pain · doi:10.1177/1744806917693003 · Cited by 204 · see citing works

Mechanical Allodynia Circuitry in the Dorsal Horn Is Defined by the Nature of the Injury

Peirs, C., Williams, S.-P. G., Zhao, X., Arokiaraj, C. M., Ferreira, D. W., Noh, M.-C., Smith, K. M., Halder, P., Corrigan, K. A., Gedeon, J. Y., et al. (2021) · Neuron · doi:10.1016/j.neuron.2020.10.027 · Cited by 190 · see citing works

Making sense out of spinal cord somatosensory development

Lai, H. C., Seal, R. P., & Johnson, J. E. (2016) · Development · doi:10.1242/dev.139592 · Cited by 188 · see citing works

Neuronal and microglial mechanisms for neuropathic pain in the spinal dorsal horn and anterior cingulate cortex

Tsuda, M., Koga, K., Chen, T., & Zhuo, M. (2017) · Journal of Neurochemistry · doi:10.1111/jnc.14001 · Cited by 167 · see citing works

Functional Divergence of Delta and Mu Opioid Receptor Organization in CNS Pain Circuits

Wang, D., Tawfik, V. L., Corder, G. F., Low, S. A., François, A., Basbaum, A. I., & Scherrer, G. (2018) · Neuron · doi:10.1016/j.neuron.2018.03.002 · Cited by 158 · see citing works

Uncovering the Cells and Circuits of Touch in Normal and Pathological Settings

Moehring, F., Halder, P., Seal, R. P., & Stucky, C. L. (2018) · Neuron · doi:10.1016/j.neuron.2018.10.019 · Cited by 155 · see citing works

NMDA Receptor Activation Underlies the Loss of Spinal Dorsal Horn Neurons and the Transition to Persistent Pain after Peripheral Nerve Injury

Inquimbert, P., Moll, M., Latrémolière, A., Tong, C., Whang, J., Sheehan, G. F., Smith, B., Korb, E., Athié, M. C. P., Babaniyi, O., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.04.107 · Cited by 138 · see citing works

Spinal Circuits Transmitting Mechanical Pain and Itch

Duan, B., Cheng, L., & Ma, Q. (2017) · Neuroscience Bulletin · doi:10.1007/s12264-017-0136-z · Cited by 132 · see citing works

Defining a Spinal Microcircuit that Gates Myelinated Afferent Input: Implications for Tactile Allodynia

Boyle, K. A., Gradwell, M. A., Yasaka, T., Dickie, A. C., Polgár, E., Ganley, R. P., Orr, D. P. H., Watanabe, M., Abraira, V. E., Kuehn, E. D., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.06.040 · Cited by 131 · see citing works

Neuronal interleukin-1 receptors mediate pain in chronic inflammatory diseases

Mailhot, B., Christin, M., Tessandier, N., Sotoudeh, C., Bretheau, F., Turmel, R., Pellerin, È., Wang, F., Bories, C., Joly-Beauparlant, C., et al. (2020) · The Journal of Experimental Medicine · doi:10.1084/jem.20191430 · Cited by 130 · see citing works

Recent advances in our understanding of the organization of dorsal horn neuron populations and their contribution to cutaneous mechanical allodynia

Peirs, C., Dallel, R., & Todd, A. J. (2020) · Journal of Neural Transmission · doi:10.1007/s00702-020-02159-1 · Cited by 131 · see citing works

A functional subdivision within the somatosensory system and its implications for pain research

Ma, Q. (2022) · Neuron · doi:10.1016/j.neuron.2021.12.015 · Cited by 108 · see citing works

RORβ Spinal Interneurons Gate Sensory Transmission during Locomotion to Secure a Fluid Walking Gait

Koch, S. C., Del Barrio, M. G., Dalet, A., Gatto, G., Günther, T., Zhang, J., Seidler, B., Saur, D., Schüle, R., & Goulding, M. (2017) · Neuron · doi:10.1016/j.neuron.2017.11.011 · Cited by 102 · see citing works

Identification of Early RET+ Deep Dorsal Spinal Cord Interneurons in Gating Pain

Cui, L., Miao, X., Liang, L., Abdus-Saboor, I., Olson, W., Fleming, M. S., Ma, M., Tao, Y.-X., & Luo, W. (2016) · Neuron · doi:10.1016/j.neuron.2016.07.038 · Cited by 100 · see citing works

Spinal ascending pathways for somatosensory information processing

Wang, L.-H., Ding, W.-Q., & Sun, Y.-G. (2022) · Trends in Neurosciences · doi:10.1016/j.tins.2022.05.005 · Cited by 100 · see citing works

A neuropeptide code for itch

Chen, Z. (2021) · Nature reviews. Neuroscience · doi:10.1038/s41583-021-00526-9 · Cited by 97 · see citing works

Neuroplasticity related to chronic pain and its modulation by microglia

Hiraga, S.-I., Itokazu, T., Nishibe, M., & Yamashita, T. (2022) · Inflammation and Regeneration · doi:10.1186/s41232-022-00199-6 · Cited by 98 · see citing works

A quantitative study of neurochemically defined populations of inhibitory interneurons in the superficial dorsal horn of the mouse spinal cord

Boyle, K. A., Gutierrez-Mecinas, M., Polgár, E., Mooney, N., O'Connor, E., Furuta, T., Watanabe, M., & Todd, A. J. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2017.08.044 · Cited by 92 · see citing works

Genetic pathway analysis reveals a major role for extracellular matrix organization in inflammatory and neuropathic pain

Parisien, M., Samoshkin, A., Tansley, S. N., Piltonen, M. H., Martin, L. J., El-Hachem, N., Dagostino, C., Allegri, M., Mogil, J. S., Khoutorsky, A., et al. (2019) · Pain · doi:10.1097/j.pain.0000000000001471 · Cited by 85 · see citing works

Central Nervous System Targets: Inhibitory Interneurons in the Spinal Cord

Hughes, D. I., & Todd, A. J. (2020) · Neurotherapeutics · doi:10.1007/s13311-020-00936-0 · Cited by 88 · see citing works

The dual role of TRPV1 in peripheral neuropathic pain: pain switches caused by its sensitization or desensitization

Gao, N., Li, M., Wang, W., Liu, Z., & Guo, Y. (2024) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2024.1400118 · Cited by 91 · see citing works

Astrocytes contribute to pain gating in the spinal cord

Xu, Q., Ford, N. C., He, S., Huang, Q., Anderson, M., Chen, Z., Yang, F., Crawford, L. K., Caterina, M. J., Guan, Y., et al. (2021) · Science Advances · doi:10.1126/sciadv.abi6287 · Cited by 84 · see citing works

The neurobiology of acute pain

Bell, A. M. (2018) · The Veterinary Journal · doi:10.1016/j.tvjl.2018.05.004 · Cited by 80 · see citing works

A machine-vision approach for automated pain measurement at millisecond timescales

Jones, J. M., Foster, W., Twomey, C. R., Burdge, J., Ahmed, O. M., Pereira, T., Wojick, J. A., Corder, G. F., Plotkin, J. B., & Abdus-Saboor, I. (2020) · eLife · doi:10.7554/elife.57258 · Cited by 77 · see citing works

Optogenetic Activation of Non-Nociceptive Aβ Fibers Induces Neuropathic Pain-Like Sensory and Emotional Behaviors after Nerve Injury in Rats

Tashima, R., Koga, K., Sekine, M., Kanehisa, K., Kohro, Y., Tominaga, K., Matsushita, K., Tozaki‐Saitoh, H., Fukazawa, Y., Inoue, K., et al. (2018) · eNeuro · doi:10.1523/eneuro.0450-17.2018 · Cited by 79 · see citing works

Neuropathic Pain Creates an Enduring Prefrontal Cortex Dysfunction Corrected by the Type II Diabetic Drug Metformin But Not by Gabapentin

Shiers, S. I., Pradhan, G., Mwirigi, J. M., Mejia, G., Ahmad, A., Kroener, S., & Price, T. J. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.0713-18.2018 · Cited by 79 · see citing works

In Vivo Interrogation of Spinal Mechanosensory Circuits

Christensen, A. J., Iyer, S. M., François, A., Vyas, S., Ramakrishnan, C., Vesuna, S., Deisseroth, K., Scherrer, G., & Delp, S. L. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.10.010 · Cited by 75 · see citing works

Neuronal diversity in the somatosensory system: bridging the gap between cell type and function

Gatto, G., Smith, K. M., Ross, S. E., & Goulding, M. (2019) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2019.03.002 · Cited by 74 · see citing works

P2 receptors, microglial cytokines and chemokines, and neuropathic pain

Tsuda, M. (2016) · Journal of Neuroscience Research · doi:10.1002/jnr.23816 · Cited by 71 · see citing works

Central and peripheral contributions of T-type calcium channels in pain

Harding, E. K., & Zamponi, G. W. (2022) · Molecular Brain · doi:10.1186/s13041-022-00923-w · Cited by 73 · see citing works

Preprotachykinin A is expressed by a distinct population of excitatory neurons in the mouse superficial spinal dorsal horn including cells that respond to noxious and pruritic stimuli

Gutièrrez‐Mecinas, M., Bell, A. M., Marin, A., Taylor, R., Boyle, K. A., Furuta, T., Watanabe, M., Polgár, E., & Todd, A. J. (2016) · Pain · doi:10.1097/j.pain.0000000000000778 · Cited by 72 · see citing works

Semi-intact ex vivo approach to investigate spinal somatosensory circuits

Hachisuka, J., Baumbauer, K. M., Omori, Y., Snyder, L. M., Koerber, H. R., & Ross, S. E. (2016) · eLife · doi:10.7554/elife.22866 · Cited by 70 · see citing works

Role of microglia and P2X4 receptors in chronic pain

Kohno, K., & Tsuda, M. (2021) · PAIN Reports · doi:10.1097/pr9.0000000000000864 · Cited by 64 · see citing works

TMEM16F Regulates Spinal Microglial Function in Neuropathic Pain States

Batti, L., Sundukova, M., Murana, E., Pimpinella, S., Reis, F. D. C., Pagani, F., Wang, H., Pellegrino, E., Perlas, E., Angelantonio, S. D., et al. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.05.039 · Cited by 64 · see citing works

Mechanisms of Tactile Sensory Phenotypes in Autism: Current Understanding and Future Directions for Research

Schaffler, M. D., Middleton, L. J., & Abdus-Saboor, I. (2019) · Current Psychiatry Reports · doi:10.1007/s11920-019-1122-0 · Cited by 65 · see citing works

Timing Mechanisms Underlying Gate Control by Feedforward Inhibition

Zhang, Y., Liu, S., Zhang, Y., Goulding, M., Wang, Y.-Q., & Ma, Q. (2018) · Neuron · doi:10.1016/j.neuron.2018.07.026 · Cited by 63 · see citing works

Human Spinal Organoid-on-a-Chip to Model Nociceptive Circuitry for Pain Therapeutics Discovery

Ao, Z., Cai, H., Wu, Z., Krzesniak, J., Tian, C., Lai, Y. Y., Mackie, K., & Guo, F. (2021) · Analytical Chemistry · doi:10.1021/acs.analchem.1c04641 · Cited by 62 · see citing works

From Mechanism to Cure: Renewing the Goal to Eliminate the Disease of Pain

Price, T. J., & Gold, M. S. (2017) · Pain Medicine · doi:10.1093/pm/pnx108 · Cited by 60 · see citing works

5-HT2AReceptor-Induced Morphological Reorganization of PKCγ-Expressing Interneurons Gates Inflammatory Mechanical Allodynia in Rat

Alba‐Delgado, C., Mountadem, S., Mermet-Joret, N., Monconduit, L., Dallel, R., Artola, A., & Antri, M. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.1294-18.2018 · Cited by 60 · see citing works

Time-dependent and selective microglia-mediated removal of spinal synapses in neuropathic pain

Yousefpour, N., Locke, S., Deamond, H., Wang, C., Marques, L., Louis, M. S., Ouellette, J., Khoutorsky, A., Koninck, Y. D., & Ribeiro‐da‐Silva, A. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112010 · Cited by 66 · see citing works

Synaptic control of spinal GRPR + neurons by local and long-range inhibitory inputs

Liu, M., Chen, X., Liang, T.-Y., Li, Q., Wang, M., Zhang, X., Li, Y.-Z., Sun, Q., & Sun, Y.-G. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1905658116 · Cited by 59 · see citing works

Facilitation of neuropathic pain by the NPY Y1 receptor-expressing subpopulation of excitatory interneurons in the dorsal horn

Nelson, T. S., Fu, W., Donahue, R. R., Corder, G. F., Hökfelt, T. G. M., Wiley, R. G., & Taylor, B. K. (2019) · Scientific Reports · doi:10.1038/s41598-019-43493-z · Cited by 58 · see citing works

Calretinin positive neurons form an excitatory amplifier network in the spinal cord dorsal horn

Smith, K. M., Browne, T. J., Davis, O. C., Coyle, A., Boyle, K. A., Watanabe, M., Dickinson, S. A., Iredale, J. A., Gradwell, M. A., Jobling, P., et al. (2019) · eLife · doi:10.7554/elife.49190 · Cited by 57 · see citing works

Cav3.2 T-type calcium channels shape electrical firing in mouse Lamina II neurons

Candelas, M., Reynders, A., Arango-Lievano, M., Neumayer, C., Fruquière, A., Demes, E., Hamid, J., Lemmers, C., Bernat, C., Monteil, A., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-39703-3 · Cited by 57 · see citing works

Presynaptic Inhibition of Pain and Touch in the Spinal Cord: From Receptors to Circuits

Comitato, A., & Bardoni, R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22010414 · Cited by 57 · see citing works

The development of pain circuits and unique effects of neonatal injury

Brewer, C. L., & Baccei, M. L. (2019) · Journal of Neural Transmission · doi:10.1007/s00702-019-02059-z · Cited by 57 · see citing works

Neuronal networks and nociceptive processing in the dorsal horn of the spinal cord

Cordero‐Erausquin, M., Inquimbert, P., Schlichter, R., & Hugel, S. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.08.048 · Cited by 54 · see citing works

Recent advances in understanding neuropathic pain: glia, sex differences, and epigenetics

Machelska, H., & Celik, M. Ö. (2016) · F1000Research · doi:10.12688/f1000research.9621.1 · Cited by 54 · see citing works

A subset of spinal dorsal horn interneurons crucial for gating touch-evoked pain-like behavior

Tashima, R., Koga, K., Yoshikawa, Y., Sekine, M., Watanabe, M., Tozaki-Saitoh, H., Furue, H., Yasaka, T., & Tsuda, M. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2021220118 · Cited by 54 · see citing works

Epidural optogenetics for controlled analgesia

Bonin, R. P., Wang, F., Desrochers-Couture, M., Gąsecka, A., Boulanger, M.-E., Côté, D. C., & Koninck, Y. D. (2016) · Molecular Pain · doi:10.1177/1744806916629051 · Cited by 53 · see citing works

A brain-to-spinal sensorimotor loop for repetitive self-grooming

Xie, Z., Li, D., Cheng, X., Pei, Q., Gu, H., Tao, T., Huang, M., Shang, C., Geng, D., Zhao, M., et al. (2021) · Neuron · doi:10.1016/j.neuron.2021.11.028 · Cited by 52 · see citing works

Spinal cord retinoic acid receptor signaling gates mechanical hypersensitivity in neuropathic pain

Cao, B., Scherrer, G., & Chen, L. (2022) · Neuron · doi:10.1016/j.neuron.2022.09.027 · Cited by 51 · see citing works

Modulation of Glycine-Mediated Spinal Neurotransmission for the Treatment of Chronic Pain

Cioffi, C. L. (2017) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.7b00956 · Cited by 48 · see citing works

Spinal Inhibitory Interneurons: Gatekeepers of Sensorimotor Pathways

Stachowski, N. J., & Dougherty, K. J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22052667 · Cited by 51 · see citing works

Insights Into Spinal Dorsal Horn Circuit Function and Dysfunction Using Optical Approaches

Harding, E. K., Fung, S. W., & Bonin, R. P. (2020) · Frontiers in Neural Circuits · doi:10.3389/fncir.2020.00031 · Cited by 51 · see citing works

Targeting spinal neuropeptide Y1 receptor-expressing interneurons to alleviate chronic pain and itch

Nelson, T. S., & Taylor, B. K. (2020) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2020.101894 · Cited by 50 · see citing works

Cell type-specific calcium imaging of central sensitization in mouse dorsal horn

Warwick, C. A., Salsovic, J., Hachisuka, J., Smith, K. M., Sheahan, T. D., Chen, H., Ibinson, J. W., Koerber, H. R., & Ross, S. E. (2022) · Nature Communications · doi:10.1038/s41467-022-32608-2 · Cited by 50 · see citing works

The histology, physiology, neurochemistry and circuitry of the substantia gelatinosa Rolandi (lamina II) in mammalian spinal cord

Merighi, A. (2018) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2018.06.012 · Cited by 50 · see citing works

Identification of Spinal Neurons Contributing to the Dorsal Column Projection Mediating Fine Touch and Corrective Motor Movements

Paixão, S., Loschek, L. F., Gaitanos, L., Morales, P. L. A., Goulding, M., & Klein, R. (2019) · Neuron · doi:10.1016/j.neuron.2019.08.029 · Cited by 46 · see citing works

Spinal neuropeptide Y Y1 receptor-expressing neurons are a pharmacotherapeutic target for the alleviation of neuropathic pain

Nelson, T. S., Sinha, G. P., dos Santos, D. F. D. S., Jukkola, P. I., Prasoon, P., Winter, M. K., McCarson, K. E., Smith, B. N., & Taylor, B. K. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2204515119 · Cited by 48 · see citing works

Recruitment of Spinoparabrachial Neurons by Dorsal Horn Calretinin Neurons

Petitjean, H., Bourojeni, F. B., Tsao, D., Davidova, A., Sotocinal, S. G., Mogil, J. S., Kania, A., & Sharif-Naeini, R. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.07.048 · Cited by 47 · see citing works

Multiscale Computer Model of the Spinal Dorsal Horn Reveals Changes in Network Processing Associated with Chronic Pain

Medlock, L., Sekiguchi, K., Hong, S., Durá-Bernal, S., Lytton, W. W., & Prescott, S. A. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.1199-21.2022 · Cited by 41 · see citing works

Spinal nociceptive circuit analysis with recombinant adeno‐associated viruses: the impact of serotypes and promoters

Haenraets, K., Foster, E., Johannssen, H. C., Kandra, V., Frezel, N., Steffen, T., Jaramillo, V., Paterna, J., Zeilhofer, H. U., & Wildner, H. (2017) · Journal of Neurochemistry · doi:10.1111/jnc.14124 · Cited by 42 · see citing works

Axo‐axonic synapses: Diversity in neural circuit function

Cover, K. K., & Mathur, B. N. (2020) · The Journal of Comparative Neurology · doi:10.1002/cne.25087 · Cited by 44 · see citing works

Contribution of dorsal horn CGRP-expressing interneurons to mechanical sensitivity

Löken, L. S., Braz, J. M., Etlin, A., Sadeghi, M., Bernstein, M. X., Jewell, M. E., Steyert, M. R., Kuhn, J., Hamel, K. A., Llewellyn‐Smith, I. J., et al. (2021) · eLife · doi:10.7554/elife.59751 · Cited by 44 · see citing works

Glycine transporter inhibitors: a new avenue for managing neuropathic pain.

Al-Khrasani, M., Mohammadzadeh, A., Balogh, M., Király, K., Barsi, S., Hajnal, B., Köles, L., Zádori, Z., & Hársing, L. (2019) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2019.07.008 · Cited by 39 · see citing works

The impact of silencing feed-forward parvalbumin-expressing inhibitory interneurons in the cortico-thalamocortical network on seizure generation and behaviour

Panthi, S., & Leitch, B. (2019) · Neurobiology of Disease · doi:10.1016/j.nbd.2019.104610 · Cited by 41 · see citing works

CD4+ αβ T cell infiltration into the leptomeninges of lumbar dorsal roots contributes to the transition from acute to chronic mechanical allodynia after adult rat tibial nerve injuries

Du, B., Ding, Y., Xiao, X., Ren, H.-Y., Su, B., & Qi, J. (2018) · Journal of Neuroinflammation · doi:10.1186/s12974-018-1115-7 · Cited by 41 · see citing works

Synergistic antipruritic effects of gamma aminobutyric acid A and B agonists in a mouse model of atopic dermatitis

Cevikbas, F., Bráz, J. M., Wang, X., Solórzano, C., Sulk, M., Buhl, T., Steinhoff, M. S., & Basbaum, A. I. (2017) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2017.02.001 · Cited by 39 · see citing works

Glycine Receptors in Spinal Nociceptive Control—An Update

Zeilhofer, H. U., Werynska, K., Gingras, J., & Yévenes, G. E. (2021) · Biomolecules · doi:10.3390/biom11060846 · Cited by 40 · see citing works

Diversity of inhibitory and excitatory parvalbumin interneuron circuits in the dorsal horn

Gradwell, M. A., Boyle, K. A., Browne, T. J., Bell, A. M., Leonardo, J., Reyes, F. S. P., Dickie, A. C., Smith, K. M., Callister, R. J., Dayas, C. V., et al. (2021) · Pain · doi:10.1097/j.pain.0000000000002422 · Cited by 39 · see citing works

Postnatal maturation of spinal dynorphin circuits and their role in somatosensation

Brewer, C. L., Styczynski, L. M., Serafin, E. K., & Baccei, M. L. (2020) · Pain · doi:10.1097/j.pain.0000000000001884 · Cited by 38 · see citing works

Neuropeptide Y-expressing dorsal horn inhibitory interneurons gate spinal pain and itch signalling

Boyle, K. A., Polgár, E., Gutièrrez‐Mecinas, M., Dickie, A. C., Cooper, A. H., Bell, A. M., Jumolea, E., Casas-Benito, A., Watanabe, M., Hughes, D. I., et al. (2023) · eLife · doi:10.7554/elife.86633 · Cited by 43 · see citing works

Excitatory and Inhibitory Neurons of the Spinal Cord Superficial Dorsal Horn Diverge in Their Somatosensory Responses and Plasticity in Vivo

Sullivan, S. J., & Sdrulla, A. D. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.1860-21.2021 · Cited by 37 · see citing works

Parabrachial Calca neurons drive nociplasticity

Condon, L. F., Yu, Y., Park, S., Cao, F., Pauli, J. L., Nelson, T. S., & Palmiter, R. D. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114057 · Cited by 38 · see citing works

Gabapentin Modulates HCN4 Channel Voltage-Dependence

Tae, H., Smith, K. M., Phillips, A. M., Boyle, K. A., Li, M., Forster, I. C., Hatch, R. J., Richardson, R., Hughes, D. I., Graham, B. A., et al. (2017) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00554 · Cited by 36 · see citing works

Spinal cords: Symphonies of interneurons across species

Wilson, A. C., & Sweeney, L. B. (2023) · Frontiers in Neural Circuits · doi:10.3389/fncir.2023.1146449 · Cited by 36 · see citing works

BDNF-TrkB signaling pathway-mediated microglial activation induces neuronal KCC2 downregulation contributing to dynamic allodynia following spared nerve injury

Hu, Z., Yu, X., Chen, P., Jin, K., Zhou, J., Wang, G., Yu, J., Wu, T., Wang, Y., Lin, F., et al. (2023) · Molecular Pain · doi:10.1177/17448069231185439 · Cited by 34 · see citing works

Developing Modern Pain Therapies

Manion, J., Waller, M. A., Clark, T., Massingham, J. N., & Neely, G. G. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.01370 · Cited by 32 · see citing works

TAFA4 relieves injury-induced mechanical hypersensitivity through LDL receptors and modulation of spinal A-type K+ current

Yoo, S., Santos, C., Reynders, A., Marics, I., Malapert, P., Gaillard, S., Charron, A., Ugolini, S., Rossignol, R., Khallouqi, A. E., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109884 · Cited by 32 · see citing works

Microglial P2X4 receptors are essential for spinal neurons hyperexcitability and tactile allodynia in male and female neuropathic mice

Gilabert, D., Duveau, A., Carracedo, S., Linck, N., Langla, A., Muramatsu, R., Koch‐Nolte, F., Rassendren, F., Grütter, T., Fossat, P., et al. (2023) · iScience · doi:10.1016/j.isci.2023.108110 · Cited by 31 · see citing works

Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition

Arokiaraj, C. M., Leone, M. J., Kleyman, M., Chamessian, A. G., Noh, M., Phan, B. N., Lopes, B. C., Corrigan, K. A., Cherupally, V. K., Yeramosu, D., et al. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114876 · Cited by 31 · see citing works

Peripheral afferents and spinal inhibitory system in dynamic and static mechanical allodynia

La, J., & Chung, J. M. (2017) · Pain · doi:10.1097/j.pain.0000000000001055 · Cited by 31 · see citing works

Human induced pluripotent stem cell-derived GABAergic interneuron transplants attenuate neuropathic pain

Manion, J., Khuong, T. M., Harney, D., Littleboy, J. B., Ruan, T., Loo, L., Costigan, M., Larance, M., Caron, L., & Neely, G. G. (2020) · Pain · doi:10.1097/j.pain.0000000000001733 · Cited by 31 · see citing works

Glycine Receptor Subtypes and Their Roles in Nociception and Chronic Pain

Martín, V. P. S., Sazo, A., Utreras, E., Moraga‐Cid, G., & Yévenes, G. E. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.848642 · Cited by 31 · see citing works

Differential Activation of Pain Circuitry Neuron Populations in a Mouse Model of Spinal Cord Injury-Induced Neuropathic Pain

Brown, E. V., Malik, A. F., Moese, E. R., McElroy, A. F., & Lepore, A. C. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.1596-21.2022 · Cited by 30 · see citing works

Distinct forms of synaptic inhibition and neuromodulation regulate calretinin-positive neuron excitability in the spinal cord dorsal horn

Smith, K. M., Boyle, K. A., Mustapa, M., Jobling, P., Callister, R. J., Hughes, D. I., & Graham, B. A. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.03.058 · Cited by 30 · see citing works

The Role Of Glial–Neuronal Metabolic Cooperation in Modulating Progression of Multiple Sclerosis and Neuropathic Pain

Robinson, R. R., Dietz, A. K., Maroof, A. M., Asmis, R., & Forsthuber, T. G. (2019) · Immunotherapy · doi:10.2217/imt-2018-0153 · Cited by 31 · see citing works

Transgenic Cross-Referencing of Inhibitory and Excitatory Interneuron Populations to Dissect Neuronal Heterogeneity in the Dorsal Horn

Browne, T. J., Gradwell, M. A., Iredale, J. A., Madden, J. F., Callister, R. J., Hughes, D. I., Dayas, C. V., & Graham, B. A. (2020) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2020.00032 · Cited by 30 · see citing works

Nerve injury disrupts temporal processing in the spinal cord dorsal horn through alterations in PV+ interneurons

Rankin, G., Chirila, A. M., Emanuel, A. J., Zhang, Z., Woolf, C. J., Drugowitsch, J., & Ginty, D. D. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.113718 · Cited by 24 · see citing works

A subset of spinal dorsal horn interneurons crucial for gating touch-evoked pain-like behavior

Tashima, R., Koga, K., Yoshikawa, Y., Sekine, M., Watanabe, M., Tozaki-Saitoh, H., Furue, H., Yasaka, T., & Tsuda, M. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2021220118 · Cited by 54 · see citing works

Diversity of inhibitory and excitatory parvalbumin interneuron circuits in the dorsal horn

Gradwell, M. A., Boyle, K. A., Browne, T. J., Bell, A. M., Leonardo, J., Reyes, F. S. P., Dickie, A. C., Smith, K. M., Callister, R. J., Dayas, C. V., et al. (2021) · Pain · doi:10.1097/j.pain.0000000000002422 · Cited by 39 · see citing works

Modulation of SK Channels via Calcium Buffering Tunes Intrinsic Excitability of Parvalbumin Interneurons in Neuropathic Pain: A Computational and Experimental Investigation

Ma, X., Miraucourt, L. S., Qiu, H., Sharif‐Naeini, R., & Khadra, A. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.0426-23.2023 · Cited by 23 · see citing works

Loss of inhibitory tone on spinal cord dorsal horn spontaneously and nonspontaneously active neurons in a mouse model of neuropathic pain

Medrano, M., Dhanasobhon, D., Yalçın, İ., Schlichter, R., & Cordero‐Erausquin, M. (2016) · Pain · doi:10.1097/j.pain.0000000000000538 · Cited by 26 · see citing works