Calretinin positive neurons form an excitatory amplifier network in the spinal cord dorsal horn

The Mouse Brain in Stereotaxic Coordinates

Paxinos, G. (2001) · Cited by 12,859 · see citing works

Cellular and Molecular Mechanisms of Pain

Basbaum, A. I., Bautista, D. M., Scherrer, G., & Julius, D. (2009) · Cell · doi:10.1016/j.cell.2009.09.028 · Cited by 4,344 · see citing works

Spared nerve injury: an animal model of persistent peripheral neuropathic pain

Décosterd, I., & Woolf, C. J. (2000) · Pain · doi:10.1016/s0304-3959(00)00276-1 · Cited by 2,317 · see citing works

Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing

Usoskin, D., Furlan, A., Islam, S., Abdo, H., Lönnerberg, P., Lou, D., Hjerling-Leffler, J., Haeggström, J., Kharchenko, O., Kharchenko, P. V., et al. (2015) · Nature Neuroscience · doi:10.1038/nn.3881 · Cited by 2,136 · see citing works

Neuronal circuitry for pain processing in the dorsal horn

Todd, A. J. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2947 · Cited by 1,475 · see citing works

Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain

Coull, J. A. M., Boudreau, D., Bachand, K., Prescott, S. A., Nault, F., Attila Gabor, S. I. K., Koninck, P. D., & Koninck, Y. D. (2003) · Nature · doi:10.1038/nature01868 · Cited by 1,118 · see citing works

Partial Peripheral Nerve Injury Promotes a Selective Loss of GABAergic Inhibition in the Superficial Dorsal Horn of the Spinal Cord

Moore, K. A., Kohno, T., Karchewski, L. A., Scholz, J., Baba, H., & Woolf, C. J. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-15-06724.2002 · Cited by 859 · see citing works

Viral-genetic tracing of the input-output organization of a central noradrenaline circuit

Schwarz, L. A., Miyamichi, K., Gao, X. J., Beier, K. T., Weissbourd, B., DeLoach, K. E., Ren, J., Ibanes, S., Malenka, R. C., Kremer, E. J., et al. (2015) · Nature · doi:10.1038/nature14600 · Cited by 744 · see citing works

Proximally targeted GABAergic synapses and gap junctions synchronize cortical interneurons

Tamás, G., Buhl, E. H., Lörincz, A., & Somogyi, P. (2000) · Nature Neuroscience · doi:10.1038/73936 · Cited by 648 · see citing works

Inhibition of Hyperalgesia by Ablation of Lamina I Spinal Neurons Expressing the Substance P Receptor

Mantyh, P. W., Rogers, S. D., Honoré, P., Allen, B. J., Ghilardi, J. R., Li, J., Daughters, R. S., Lappi, D. A., Wiley, R. G., & Simone, D. A. (1997) · Science · doi:10.1126/science.278.5336.275 · Cited by 634 · see citing works

Identification of Spinal Circuits Transmitting and Gating Mechanical Pain

Duan, B., Cheng, L., Bourane, S., Britz, O., Padilla, C., Garcia-Campmany, L., Krashes, M., Knowlton, W., Velasquez, T., Ren, X., et al. (2014) · Cell · doi:10.1016/j.cell.2014.11.003 · Cited by 582 · see citing works

Neural circuits for pain: Recent advances and current views

Peirs, C., & Seal, R. P. (2016) · Science · doi:10.1126/science.aaf8933 · Cited by 481 · see citing works

A Simplified Up-Down Method (SUDO) for Measuring Mechanical Nociception in Rodents Using von Frey Filaments

Bonin, R. P., Bories, C., & Koninck, Y. D. (2014) · Molecular Pain · doi:10.1186/1744-8069-10-26 · Cited by 468 · see citing works

Loss of Inhibitory Interneurons in the Dorsal Spinal Cord and Elevated Itch in Bhlhb5 Mutant Mice

Ross, S. E., Mardinly, A. R., McCord, A. E., Zurawski, J. D., Cohen, S., Jung, C. C., Hu, L. S., Mok, S. I., Shah, A., Savner, E. M., et al. (2010) · Neuron · doi:10.1016/j.neuron.2010.02.025 · Cited by 445 · see citing works

Disinhibition Opens the Gate to Pathological Pain Signaling in Superficial Neurokinin 1 Receptor-Expressing Neurons in Rat Spinal Cord

Torsney, C., & MacDermott, A. B. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.4584-05.2006 · Cited by 407 · see citing works

Fast Synaptic Inhibition in Spinal Sensory Processing and Pain Control

Zeilhofer, H., Wildner, H., & Yévenes, G. E. (2012) · Physiological Reviews · doi:10.1152/physrev.00043.2010 · Cited by 364 · see citing works

A Brainstem-Spinal Cord Inhibitory Circuit for Mechanical Pain Modulation by GABA and Enkephalins

François, A., Low, S. A., Sypek, E. I., Christensen, A. J., Sotoudeh, C., Beier, K. T., Ramakrishnan, C., Ritola, K., Sharif‐Naeini, R., Deisseroth, K. A., et al. (2017) · Neuron · doi:10.1016/j.neuron.2017.01.008 · Cited by 354 · see citing works

Targeted Ablation, Silencing, and Activation Establish Glycinergic Dorsal Horn Neurons as Key Components of a Spinal Gate for Pain and Itch

Foster, E., Wildner, H., Tudeau, L., Haueter, S., Ralvenius, W. T., Jegen, M., Johannssen, H. C., Hösli, L., Haenraets, K., Ghanem, A., et al. (2015) · Neuron · doi:10.1016/j.neuron.2015.02.028 · Cited by 350 · see citing works

Dorsal Horn Circuits for Persistent Mechanical Pain

Peirs, C., Williams, S.-P. G., Zhao, X., Walsh, C. E., Gedeon, J. Y., Cagle, N. E., Goldring, A. C., Hioki, H., Liu, Z., Marell, P. S., et al. (2015) · Neuron · doi:10.1016/j.neuron.2015.07.029 · Cited by 327 · see citing works

Dorsal Horn Parvalbumin Neurons Are Gate-Keepers of Touch-Evoked Pain after Nerve Injury

Petitjean, H., Pawlowski, S. A., Fraine, S. L., Sharif, B., Hamad, D., Fatima, T., Berg, J., Brown, C. M., Jan, L.-Y., Ribeiro-da-Silva, A., et al. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.09.080 · Cited by 326 · see citing works

A feed-forward spinal cord glycinergic neural circuit gates mechanical allodynia

Lü, Y., Dong, H., Gao, Y., Gong, Y., Ren, Y., Gu, N., Zhou, S., Xia, N., Sun, Y., Ji, R., et al. (2013) · Journal of Clinical Investigation · doi:10.1172/jci70026 · Cited by 287 · see citing works

In VivoLabeling of Parvalbumin-Positive Interneurons and Analysis of Electrical Coupling in Identified Neurons

Meyer, A. H., Katona, I., Blatow, M., Rozov, A. V., & Monyer, H. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-16-07055.2002 · Cited by 286 · see citing works

A Specific Inhibitory Pathway between Substantia Gelatinosa Neurons Receiving Direct C-Fiber Input

Lü, Y., & Perl, E. R. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-25-08752.2003 · Cited by 286 · see citing works

Modular Organization of Excitatory Circuits between Neurons of the Spinal Superficial Dorsal Horn (Laminae I and II)

Lü, Y., & Perl, E. R. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.0102-05.2005 · Cited by 255 · see citing works

Synaptic plasticity in pathological pain

Luo, C., Kuner, T., & Kuner, R. (2014) · Trends in Neurosciences · doi:10.1016/j.tins.2014.04.002 · Cited by 253 · see citing works

Direct Activation of Rat Spinal Dorsal Horn Neurons by Prostaglandin E2

Baba, H., Kohno, T., Moore, K. A., & Woolf, C. J. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-05-01750.2001 · Cited by 228 · see citing works

Glycine Inhibitory Dysfunction Turns Touch into Pain through PKCgamma Interneurons

Miraucourt, L. S., Dallel, R., & Voisin, D. L. (2007) · PLoS ONE · doi:10.1371/journal.pone.0001116 · Cited by 208 · see citing works

The properties of neurones recorded in the superficial dorsal horn of the rat spinal cord

Woolf, C. J., & Fitzgerald, M. (1983) · The Journal of Comparative Neurology · doi:10.1002/cne.902210307 · Cited by 207 · see citing works

The glycinergic control of spinal pain processing

Zeilhofer, H. U. (2005) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-005-5107-2 · Cited by 206 · see citing works

Impaired motor coordination and Purkinje cell excitability in mice lacking calretinin

Schiffmann, S. N., Cheron, G. A., Lohof, A. M., d’Alcantara, P., Meyer, M., Parmentier, M., & Schurmans, S. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.9.5257 · Cited by 199 · see citing works

Innocuous, Not Noxious, Input Activates PKCγ Interneurons of the Spinal Dorsal Horn via Myelinated Afferent Fibers

Neumann, S., Braz, J. M., Skinner, K., Llewellyn‐Smith, I. J., & Basbaum, A. I. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1259-08.2008 · Cited by 175 · see citing works

Signaling complex formation of phospholipase Cβ4 with metabotropic glutamate receptor type 1α and 1,4,5‐trisphosphate receptor at the perisynapse and endoplasmic reticulum in the mouse brain

Nakamura, M., Sato, K., Fukaya, M., Araishi, K., Aiba, A., Kano, M., & Watanabe, M. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03768.x · Cited by 168 · see citing works

Two calretinin-positive GABAergic cell types in layer 2/3 of the mouse neocortex provide different forms of inhibition

Caputi, A., Rozov, A., Blatow, M., & Monyer, H. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhn175 · Cited by 154 · see citing works

Excitatory interneurons dominate sensory processing in the spinal substantia gelatinosa of rat

Santos, S. F. A., Rebelo, S., Derkach, V. A., & Safronov, B. V. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2006.126912 · Cited by 148 · see citing works

Sexual dimorphism in the organization of the rat hypothalamic infundibular area

Ciofi, P., Leroy, D., & Tramu, G. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.05.041 · Cited by 140 · see citing works

Morphological, biophysical and synaptic properties of glutamatergic neurons of the mouse spinal dorsal horn

Punnakkal, P., von Schoultz, C., Haenraets, K., Wildner, H., & Zeilhofer, H. U. (2013) · The Journal of Physiology · doi:10.1113/jphysiol.2013.264937 · Cited by 131 · see citing works

Defining a Spinal Microcircuit that Gates Myelinated Afferent Input: Implications for Tactile Allodynia

Boyle, K. A., Gradwell, M. A., Yasaka, T., Dickie, A. C., Polgár, E., Ganley, R. P., Orr, D. P. H., Watanabe, M., Abraira, V. E., Kuehn, E. D., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.06.040 · Cited by 131 · see citing works

A Quantitative Study of Inhibitory Interneurons in Laminae I-III of the Mouse Spinal Dorsal Horn

Polgár, E., Durrieux, C., Hughes, D. I., & Todd, A. J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0078309 · Cited by 123 · see citing works

Inhibition and Synchronization of Basal Amygdala Principal Neuron Spiking by Parvalbumin-Positive Interneurons

Woodruff, A. R., & Sah, P. (2007) · Journal of Neurophysiology · doi:10.1152/jn.00739.2007 · Cited by 111 · see citing works

Identification of Early RET+ Deep Dorsal Spinal Cord Interneurons in Gating Pain

Cui, L., Miao, X., Liang, L., Abdus-Saboor, I., Olson, W., Fleming, M. S., Ma, M., Tao, Y.-X., & Luo, W. (2016) · Neuron · doi:10.1016/j.neuron.2016.07.038 · Cited by 100 · see citing works

Immunocytochemical study of somatostatin, neurotensin, GABA, and glycine in rat spinal dorsal horn

Proudlock, F. A., SPIKE, R. C., & Todd, A. J. (1993) · The Journal of Comparative Neurology · doi:10.1002/cne.903270210 · Cited by 92 · see citing works

Functional heterogeneity of calretinin‐expressing neurons in the mouse superficial dorsal horn: implications for spinal pain processing

Smith, K. M., Boyle, K. A., Madden, J. F., Dickinson, S. A., Jobling, P., Callister, R. J., Hughes, D. I., & Graham, B. A. (2015) · The Journal of Physiology · doi:10.1113/jp270855 · Cited by 88 · see citing works

In vivo responses of mouse superficial dorsal horn neurones to both current injection and peripheral cutaneous stimulation

Graham, B. A., Brichta, A. M., & Callister, R. J. (2004) · The Journal of Physiology · doi:10.1113/jphysiol.2004.072645 · Cited by 82 · see citing works

Synaptic pathways and inhibitory gates in the spinal cord dorsal horn

Takazawa, T., & MacDermott, A. B. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05501.x · Cited by 82 · see citing works

A quantitative study of neurochemically defined excitatory interneuron populations in laminae I–III of the mouse spinal cord

Gutierrez-Mecinas, M., Furuta, T., Watanabe, M., & Todd, A. J. (2016) · Molecular Pain · doi:10.1177/1744806916629065 · Cited by 81 · see citing works

In Vivo Interrogation of Spinal Mechanosensory Circuits

Christensen, A. J., Iyer, S. M., François, A., Vyas, S., Ramakrishnan, C., Vesuna, S., Deisseroth, K., Scherrer, G., & Delp, S. L. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.10.010 · Cited by 75 · see citing works

Preprotachykinin A is expressed by a distinct population of excitatory neurons in the mouse superficial spinal dorsal horn including cells that respond to noxious and pruritic stimuli

Gutièrrez‐Mecinas, M., Bell, A. M., Marin, A., Taylor, R., Boyle, K. A., Furuta, T., Watanabe, M., Polgár, E., & Todd, A. J. (2016) · Pain · doi:10.1097/j.pain.0000000000000778 · Cited by 72 · see citing works

Immunohistochemical localization of calretinin in the dorsal root ganglion and spinal cord of the rat

Ren, K., Ruda, M. A., & Jacobowitz, D. M. (1993) · Brain Research Bulletin · doi:10.1016/0361-9230(93)90004-u · Cited by 68 · see citing works

Neuronal calcium-binding proteins 1/2 localize to dorsal root ganglia and excitatory spinal neurons and are regulated by nerve injury

Zhang, M.-D., Tortoriello, G., Hsueh, B., Tomer, R., Li, Y., Mitsios, N., Borgius, L., Grant, G., Kiehn, O., Watanabe, M., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1402318111 · Cited by 58 · see citing works

The murine neurokinin NK1 receptor gene contributes to the adult hypoxic facilitation of ventilation

Ptak, K., Burnet, H., Blanchi, B., Sieweke, M. H., Felipe, C. D., Hunt, S. P., Monteau, R., & Hilaire, G. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.02305.x · Cited by 56 · see citing works

HCN4 subunit expression in fast-spiking interneurons of the rat spinal cord and hippocampus

Hughes, D. I., Boyle, K. A., Kinnon, C. M., Bilsland, C., Quayle, J. A., Callister, R. J., & Graham, B. A. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.01.028 · Cited by 55 · see citing works

Altered inhibitory synaptic transmission in superficial dorsal horn neurones in spastic and oscillator mice

Graham, B. A., Schofield, P. R., Sah, P., & Callister, R. J. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2003.049064 · Cited by 54 · see citing works

Epidural optogenetics for controlled analgesia

Bonin, R. P., Wang, F., Desrochers-Couture, M., Gąsecka, A., Boulanger, M.-E., Côté, D. C., & Koninck, Y. D. (2016) · Molecular Pain · doi:10.1177/1744806916629051 · Cited by 53 · see citing works

Transplant restoration of spinal cord inhibitory controls ameliorates neuropathic itch

Bráz, J. M., Juarez-Salinas, D. L., Ross, S. E., & Basbaum, A. I. (2014) · Journal of Clinical Investigation · doi:10.1172/jci75214 · Cited by 47 · see citing works

Wind-up in lamina I spinoparabrachial neurons: a role for reverberatory circuits

Hachisuka, J., Omori, Y., Chiang, M. C., Gold, M. S., Koerber, H. R., & Ross, S. E. (2018) · Pain · doi:10.1097/j.pain.0000000000001229 · Cited by 43 · see citing works

Altered potassium channel function in the superficial dorsal horn of the spastic mouse

Graham, B. A., Brichta, A. M., Schofield, P. R., & Callister, R. J. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2007.138198 · Cited by 41 · see citing works

Adjuvant analgesics in acute pain

Lui, F., & Ng, K. (2011) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2011.521743 · Cited by 40 · see citing works

Localization and osmotic regulation of vesicular glutamate transporter-2 in magnocellular neurons of the rat hypothalamus

Hrabovszky, E., Csapó, Á. K., Kalló, I., Wilheim, T., Turi, G. F., & Liposits, Z. (2006) · Neurochemistry International · doi:10.1016/j.neuint.2005.12.013 · Cited by 38 · see citing works

Inhibitory Interneurons That Express GFP in thePrP-GFPMouse Spinal Cord Are Morphologically Heterogeneous, Innervated by Several Classes of Primary Afferent and Include Lamina I Projection Neurons among Their Postsynaptic Targets

Ganley, R. P., Iwagaki, N., del Río, P., Baseer, N., Dickie, A. C., Boyle, K. A., Polgár, E., Watanabe, M., Abraira, V. E., Zimmerman, A., et al. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.0406-15.2015 · Cited by 38 · see citing works

Inhibitory regulation of the pain gate and how its failure causes pathological pain

Price, T. J., & Prescott, S. A. (2015) · Pain · doi:10.1097/j.pain.0000000000000139 · Cited by 37 · see citing works

Probing glycine receptor stoichiometry in superficial dorsal horn neurones using the spasmodic mouse

Graham, B. A., Tadros, M. A., Schofield, P. R., & Callister, R. J. (2011) · The Journal of Physiology · doi:10.1113/jphysiol.2011.206326 · Cited by 34 · see citing works

Distinct forms of synaptic inhibition and neuromodulation regulate calretinin-positive neuron excitability in the spinal cord dorsal horn

Smith, K. M., Boyle, K. A., Mustapa, M., Jobling, P., Callister, R. J., Hughes, D. I., & Graham, B. A. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.03.058 · Cited by 30 · see citing works

Separate Inhibitory and Excitatory Components Underlying Receptive Field Organization in Superficial Medullary Dorsal Horn Neurons

Kato, G., Kosugi, M., Mizuno, M., & Strassman, A. M. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.4474-11.2011 · Cited by 19 · see citing works

Temporal and spatial dynamics of peripheral afferent-evoked activity in the dorsal horn recorded in rat spinal cord slices

Yu, F., Zhao, Z., He, T., Yu, Y., Li, Z., & Chen, J. (2017) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2017.04.012 · Cited by 5 · see citing works

A harmonized atlas of mouse spinal cord cell types and their spatial organization

Russ, D. E., Cross, R. B. P., Li, L., Koch, S. C., Matson, K. J. E., Yadav, A., Alkaslasi, M. R., Lee, D. I., Le Pichon, C. E., Menon, V., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-25125-1 · Cited by 255 · see citing works

A cellular taxonomy of the adult human spinal cord

Yadav, A., Matson, K. J. E., Li, L., Hua, I., Petrescu, J., Kang, K., Alkaslasi, M. R., Lee, D. I., Hasan, S., Galuta, A., et al. (2023) · Neuron · doi:10.1016/j.neuron.2023.01.007 · Cited by 212 · see citing works

Mechanical Allodynia Circuitry in the Dorsal Horn Is Defined by the Nature of the Injury

Peirs, C., Williams, S.-P. G., Zhao, X., Arokiaraj, C. M., Ferreira, D. W., Noh, M.-C., Smith, K. M., Halder, P., Corrigan, K. A., Gedeon, J. Y., et al. (2021) · Neuron · doi:10.1016/j.neuron.2020.10.027 · Cited by 190 · see citing works

A Functional Topographic Map for Spinal Sensorimotor Reflexes

Gatto, G., Bourane, S., Ren, X., Di Costanzo, S., Fenton, P. K., Halder, P., Seal, R. P., & Goulding, M. D. (2021) · Neuron · doi:10.1016/j.neuron.2020.10.003 · Cited by 92 · see citing works

Mediators of Neuropathic Pain; Focus on Spinal Microglia, CSF-1, BDNF, CCL21, TNF-α, Wnt Ligands, and Interleukin 1β

Boakye, P. A., Tang, S.-J., & Smith, P. A. (2021) · Frontiers in Pain Research · doi:10.3389/fpain.2021.698157 · Cited by 102 · see citing works

Targeting spinal neuropeptide Y1 receptor-expressing interneurons to alleviate chronic pain and itch

Nelson, T. S., & Taylor, B. K. (2020) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2020.101894 · Cited by 50 · see citing works

Cell type-specific calcium imaging of central sensitization in mouse dorsal horn

Warwick, C. A., Salsovic, J., Hachisuka, J., Smith, K. M., Sheahan, T. D., Chen, H., Ibinson, J. W., Koerber, H. R., & Ross, S. E. (2022) · Nature Communications · doi:10.1038/s41467-022-32608-2 · Cited by 50 · see citing works

Neuropathic pain; what we know and what we should do about it

Smith, P. A. (2023) · Frontiers in Pain Research · doi:10.3389/fpain.2023.1220034 · Cited by 49 · see citing works

Multiscale Computer Model of the Spinal Dorsal Horn Reveals Changes in Network Processing Associated with Chronic Pain

Medlock, L., Sekiguchi, K., Hong, S., Durá-Bernal, S., Lytton, W. W., & Prescott, S. A. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.1199-21.2022 · Cited by 41 · see citing works

Contribution of dorsal horn CGRP-expressing interneurons to mechanical sensitivity

Löken, L. S., Braz, J. M., Etlin, A., Sadeghi, M., Bernstein, M. X., Jewell, M. E., Steyert, M. R., Kuhn, J., Hamel, K. A., Llewellyn‐Smith, I. J., et al. (2021) · eLife · doi:10.7554/elife.59751 · Cited by 44 · see citing works

Dissecting the Neural Circuitry for Pain Modulation and Chronic Pain: Insights from Optogenetics

Guo, F., Du, Y., Qu, F.-H., Lin, S.-D., Chen, Z., & Zhang, S. (2022) · Neuroscience Bulletin · doi:10.1007/s12264-022-00835-8 · Cited by 40 · see citing works

Diversity of inhibitory and excitatory parvalbumin interneuron circuits in the dorsal horn

Gradwell, M. A., Boyle, K. A., Browne, T. J., Bell, A. M., Leonardo, J., Reyes, F. S. P., Dickie, A. C., Smith, K. M., Callister, R. J., Dayas, C. V., et al. (2021) · Pain · doi:10.1097/j.pain.0000000000002422 · Cited by 39 · see citing works

Differential Activation of Pain Circuitry Neuron Populations in a Mouse Model of Spinal Cord Injury-Induced Neuropathic Pain

Brown, E. V., Malik, A. F., Moese, E. R., McElroy, A. F., & Lepore, A. C. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.1596-21.2022 · Cited by 30 · see citing works

Spinoparabrachial projection neurons form distinct classes in the mouse dorsal horn

Browne, T. J., Smith, K. M., Gradwell, M. A., Iredale, J. A., Dayas, C. V., Callister, R. J., Hughes, D. I., & Graham, B. A. (2021) · Pain · doi:10.1097/j.pain.0000000000002194 · Cited by 29 · see citing works

Projection Neuron Axon Collaterals in the Dorsal Horn: Placing a New Player in Spinal Cord Pain Processing

Browne, T. J., Hughes, D. I., Dayas, C. V., Callister, R. J., & Graham, B. A. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.560802 · Cited by 26 · see citing works

Neurochemical atlas of the cat spinal cord

Veshchitskii, A. A., Shkorbatova, P. Y., & Merkulyeva, N. S. (2022) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2022.1034395 · Cited by 22 · see citing works

Role of C-tactile fibers in pain modulation: animal and human perspectives

Larsson, M., & Nagi, S. S. (2021) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2021.09.005 · Cited by 20 · see citing works

Chronic Orchialgia Stemming From Lumbar Disc Herniation: A Case Report and Brief Review

Chu, E. C., & Wong, A. Y. L. (2021) · American Journal of Men s Health · doi:10.1177/15579883211018431 · Cited by 19 · see citing works

Calretinin-expressing islet cells are a source of pre- and post-synaptic inhibition of non-peptidergic nociceptor input to the mouse spinal cord

Davis, O., Dickie, A. C., Mustapa, M., Boyle, K. A., Browne, T. J., Gradwell, M. A., Smith, K. M., Polgár, E., Bell, A. M., Kókai, É., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-38605-9 · Cited by 19 · see citing works

An electrophysiologist’s guide to dorsal horn excitability and pain

Rivera‐Arconada, I., Baccei, M. L., Lopez-Garcia, J. A., & Bardoni, R. (2025) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2025.1548252 · Cited by 18 · see citing works

Slick Potassium Channels Control Pain and Itch in Distinct Populations of Sensory and Spinal Neurons in Mice

Flauaus, C., Engel, P., Zhou, F., Petersen, J., Ruth, P., Lukowski, R., Schmidtko, A., & Lu, R. (2022) · Anesthesiology · doi:10.1097/aln.0000000000004163 · Cited by 17 · see citing works

Local production of corticotropin-releasing hormone in prefrontal cortex modulates male-specific novelty exploration

Riad, M. H., Park, K., Ibáñez-Tallon, I., & Heintz, N. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2211454119 · Cited by 18 · see citing works

Chronic MPTP in Mice Damage-specific Neuronal Phenotypes within Dorsal Laminae of the Spinal Cord

Biagioni, F., Vivacqua, G., Lazzeri, G., Ferese, R., Iannacone, S., Onori, P., Morini, S., D’Este, L., & Fornai, F. (2020) · Neurotoxicity Research · doi:10.1007/s12640-020-00313-x · Cited by 14 · see citing works

c-Maf-positive spinal cord neurons are critical elements of a dorsal horn circuit for mechanical hypersensitivity in neuropathy

Frezel, N., Ranucci, M., Foster, E., Wende, H., Pelczar, P., Mendes, R., Ganley, R. P., Werynska, K., d‘Aquin, S., Beccarini, C., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112295 · Cited by 13 · see citing works

Differential Neuronal Activation of Nociceptive Pathways in Neuropathic Pain After Spinal Cord Injury

He, Z., Zhang, J., Xu, J. L., Wang, Y., Zheng, X., & Wang, W. (2025) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-025-01532-6 · Cited by 11 · see citing works

Making connections: recent advances in spinal cord dorsal horn circuitry

Smith, K. M., & Ross, S. E. (2020) · Pain · doi:10.1097/j.pain.0000000000001980 · Cited by 10 · see citing works

Synaptic Targets of Glycinergic Neurons in Laminae I–III of the Spinal Dorsal Horn

Miranda, C. O., Hegedűs, K., Kis, G. N., & Antal, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24086943 · Cited by 8 · see citing works

Using DeepLabCut-Live to probe state dependent neural circuits of behavior with closed-loop optogenetic stimulation

Gonzalez, M., Gradwell, M. A., Thackray, J. K., Temkar, K. K., Patel, K., & Abraira, V. E. (2025) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2025.110495 · Cited by 7 · see citing works

Spinal glycinergic currents are reduced in a rat model of neuropathic pain following partial nerve ligation but not chronic constriction injury

Natale, C. A., Christie, M. J., & Aubrey, K. R. (2022) · Journal of Neurophysiology · doi:10.1152/jn.00451.2022 · Cited by 7 · see citing works

Neuronal density and expression of calcium‐binding proteins across the layers of the superior colliculus in the common marmoset (Callithrix jacchus)

Chong, M. H. Y., Worthy, K. H., Rosa, M. G. P., & Atapour, N. (2022) · The Journal of Comparative Neurology · doi:10.1002/cne.25388 · Cited by 6 · see citing works

Pre-Synaptic GABAA in NaV1.8+ Primary Afferents Is Required for the Development of Punctate but Not Dynamic Mechanical Allodynia following CFA Inflammation

Liu, S., Bonalume, V., Gao, Q., Chen, J. T.-C., Rohr, K., Hu, J., & Carr, R. W. (2022) · Cells · doi:10.3390/cells11152390 · Cited by 6 · see citing works

Functional and anatomical analyses of active spinal circuits in a mouse model of chronic pain

Targowska‐Duda, K. M., Peters, D., Marcus, J. S., Zribi, G., Toll, L., & Ozawa, A. (2023) · Pain · doi:10.1097/j.pain.0000000000003068 · Cited by 6 · see citing works

Distinct expression profile reveals glia involvement in the trigeminal system attributing to post-traumatic headache

Nagarajan, G., & Zhang, Y. (2024) · The Journal of Headache and Pain · doi:10.1186/s10194-024-01897-x · Cited by 5 · see citing works

Distribution of Calretinin-Immunopositive Neurons in the Cat Lumbar Spinal Cord

Veshchitskii, A. A., Евгеньевич, М. П., & Merkulyeva, N. S. (2021) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s0022093021040074 · Cited by 4 · see citing works

Quantitative spatial analysis reveals that the local axons of lamina I projection neurons and interneurons exhibit distributions that predict distinct roles in spinal sensory processing

Kókai, É., Luz, L. L., Fernandes, E. C., Safronov, B. V., Poisbeau, P., & Szűcs, P. (2022) · The Journal of Comparative Neurology · doi:10.1002/cne.25413 · Cited by 3 · see citing works

Preclinical long-term safety of intraspinal transplantation of human dorsal spinal GABA neural progenitor cells

Zheng, X., Liu, Z., He, Z., Xu, J., Wang, Y., Gong, C.-Z., Zhang, R., Zhang, S., Chen, H., & Wang, W. (2023) · iScience · doi:10.1016/j.isci.2023.108306 · Cited by 3 · see citing works

Influence of Early-Life Stress on the Excitability of Dynorphin Neurons in the Adult Mouse Dorsal Horn

Harbour, K., & Baccei, M. L. (2024) · Journal of Pain · doi:10.1016/j.jpain.2024.104609 · Cited by 3 · see citing works

Lateral lamina V projection neuron axon collaterals connect sensory processing across the dorsal horn of the mouse spinal cord

Browne, T. J., Smith, K. M., Gradwell, M. A., Dayas, C. V., Callister, R. J., Hughes, D. I., & Graham, B. A. (2024) · Scientific Reports · doi:10.1038/s41598-024-73620-4 · Cited by 3 · see citing works

Neuroanatomical and neurochemical atlas of the spiny mouse (Acomys cahirinus) spinal cord

Veshchitskii, A. A., Shkorbatova, P. Y., & Merkulyeva, N. S. (2025) · Brain Structure and Function · doi:10.1007/s00429-025-02982-w · Cited by 3 · see citing works

‘Optical Von-Frey’ method to determine nociceptive thresholds: a novel paradigm for preclinical pain assessment and analgesic screeningPreprint

Iredale, J. A., Pearl, A. J., Callister, R. J., Dayas, C. V., Manning, E. E., & Graham, B. A. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.11.02.565390 · Cited by 3 · see citing works

Targeting Spinal Dorsal Horn Sensitisation in Chronic Pain: Mechanisms and Translational Strategies

Krotov, V., & Kopach, O. (2026) · Neuroscience Bulletin · doi:10.1007/s12264-026-01642-1 · Cited by 2 · see citing works

Deficiency of calretinin in prefrontal cortex causes behavioral deficits relevant to autism spectrum disorder in mice

Zhang, Y., Zhao, X., Gao, C., Shi, S., Chen, M., Guo, B., Hu, S., Mei, D., Duan, X., & Wang, X. (2025) · Molecular Brain · doi:10.1186/s13041-025-01233-7 · Cited by 2 · see citing works

A neural tract tracing study on synaptic connections for cortical glutamatergic terminals and cervical spinal calretinin neurons in rats

Huang, Z., Sun, L., Zheng, X., Zhang, Y., Zhu, Y., Chen, T., Chen, Z., Ja, L., OuYang, L., Zhu, Y., et al. (2023) · Frontiers in Neural Circuits · doi:10.3389/fncir.2023.1086873 · Cited by 2 · see citing works

The neuronal cell types of the spinal cord

Koch, S. C., & Levine, A. J. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-819260-3.00005-6 · Cited by 2 · see citing works

Comparative brain proteome analysis of an Indole Alkaloid of Kratom, Mitragynine and Kratom juice in rats

Owaid, S. J., Yunusa, S., Gam, L., & Hassan, Z. (2025) · Behavioural Brain Research · doi:10.1016/j.bbr.2025.115709 · Cited by 1 · see citing works

A mathematical model of dorsal horn circuits’ contribution to neuropathic pain

Ramne, M. (2025) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc58623.2025.11253737 · Cited by 1 · see citing works

Channelrhodopsin-2 Assisted Circuit Mapping in the Spinal Cord Dorsal Horn

Smith, K. M., & Graham, B. A. (2022) · Neuromethods · doi:10.1007/978-1-0716-2039-7_18 · Cited by 1 · see citing works

Dorsal horn CGRP-expressing interneurons contribute to nerve injury-induced mechanical hypersensitivityPreprint

Löken, L. S., Etlin, A., Bernstein, M., Steyert, M. R., Kuhn, J., Hamel, K., Llewellyn‐Smith, I. J., BRAZ, J. P. G., & Basbaum, A. I. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.06.08.131839 · Cited by 1 · see citing works

Three neurotransmitters regulate diverse inhibitory and excitatory Parvalbumin interneuron circuits in the dorsal hornPreprint

Gradwell, M. A., Boyle, K., Browne, T. J., Dickie, A. C., Bell, A., Leonardo, J., Reyes, F. S. P., Smith, K., Callister, R., Dayas, C. V., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.12.23.424233

A computational model of the integration of noxious and innocuous input in the dorsal hornPreprint

Ramne, M., & Ortiz-Catalan, M. (2022) · Research Square · doi:10.21203/rs.3.rs-2197547/v1

Spinal interneurons and pain

Noh, M., Lee, S., Arokiaraj, C. M., & Seal, R. P. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-819260-3.00006-8

Comparison of NMDA Receptor Subunit RNA Expression in the Spinal Dorsal Horn Across Species (Mice, Rats, Humans), Sex, Laminar Location and Neuronal Subtypes using Single Cell RNA Sequencing Data and qRT-PCR

Martin, N. (2023) · doi:10.22215/etd/2023-15695

Organ-Specific Small Protein Networks in 100 kDa Ultrafiltrates: Functional Analysis and Implications for Neuroregenerative Medicine

Slivka, J. P., Bauer, C., Halhouli, T., Younsi, A., Wong, M. B., Chan, M. K. S., & Skutella, T. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26146659

Selective Optogenetic Inhibition of Slow Conducting Fibers at the Level of the Sciatic Nerve Trunk in the Mouse

Ardren, M. G., Matarazzo, J. V., Ajay, E. A., Thompson, A. C., Payne, S. C., Fallon, J. B., & Richardson, R. T. (2025) · Neuromodulation Technology at the Neural Interface · doi:10.1016/j.neurom.2025.09.304

Calretinin Contributes to Trigeminal Neuropathic Pain Downstream of Cavα2δ1

Wang, Y.-Q., Liu, W.-B., Cui, W.-Q., Guo, T.-T., Chen, T., Sun, W.-S., & Chu, Y.-X. (2026) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.5c00689

Hypoactivity, abnormal development of dendrites relevant to impaired synaptic transmission of calretinin-expressing interneurons in the medial prefrontal cortex underlies social deficits of mouse model in autism

Chen, M., Zhao, K., Gao, C., Mei, D., Shi, S., wang, L., Sun, L., Guo, J., Guo, B., Zhao, S., et al. (2026) · Translational Psychiatry · doi:10.1038/s41398-026-04123-1

Whole-Body Vibration After Compressive Spinal Cord-Injury in Rats Restores Dorsal Horn Synaptic Relations and Alleviates Pain-Associated Behavior

Rink, S., Krueger, M., Zamfirov, M., Muthuraman, M., Schaufler, D., Sarıkçıoğlu, L., Bilmen, S., Vogt, J., Endle, H., Belenska-Todorova, L. F., et al. (2026) · Restorative Neurology and Neuroscience · doi:10.1177/09226028261464314

Recruitment of Spinoparabrachial Neurons by Dorsal Horn Calretinin Neurons

Petitjean, H., Bourojeni, F. B., Tsao, D., Davidova, A., Sotocinal, S. G., Mogil, J. S., Kania, A., & Sharif-Naeini, R. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.07.048 · Cited by 47 · see citing works

Functional heterogeneity of calretinin‐expressing neurons in the mouse superficial dorsal horn: implications for spinal pain processing

Smith, K. M., Boyle, K. A., Madden, J. F., Dickinson, S. A., Jobling, P., Callister, R. J., Hughes, D. I., & Graham, B. A. (2015) · The Journal of Physiology · doi:10.1113/jp270855 · Cited by 88 · see citing works

Dorsal horn calretinin neurons mediate pain through a parabrachial ascending pathway

Petitjean, H., Bourojeni, F. B., Tsao, D., Sotocinal, S. G., Mogil, J. S., Kania, A., & Sharif‐Naeini, R. (2018) · Journal of Pain · doi:10.1016/j.jpain.2017.12.057

Expression of Calretinin Among Different Neurochemical Classes of Interneuron in the Superficial Dorsal Horn of the Mouse Spinal Cord

Gutièrrez‐Mecinas, M., Davis, O., Polgár, E., Shahzad, M., Navarro-Batista, K., Furuta, T., Watanabe, M., Hughes, D. I., & Todd, A. J. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.12.009 · Cited by 35 · see citing works

Calretinin-expressing interneurons in the mouse spinal cord

Mustapa, M. (2018) · Enlighten: Theses (The University of Glasgow)