Damage to white matter bottlenecks contributes to language impairments after left hemispheric stroke
Open accessAbstract
Damage to the white matter underlying the left posterior temporal lobe leads to deficits in multiple language functions. The posterior temporal white matter may correspond to a bottleneck where both dorsal and ventral language pathways are vulnerable to simultaneous damage. Damage to a second putative white matter bottleneck in the left deep prefrontal white matter involving projections associated with ventral language pathways and thalamo-cortical projections has recently been proposed as a source of semantic deficits after stroke. Here, we first used white matter atlases to identify the previously described white matter bottlenecks in the posterior temporal and deep prefrontal white matter. We then assessed the effects of damage to each region on measures of verbal fluency, picture naming, and auditory semantic decision-making in 43 chronic left hemispheric stroke patients. Damage to the posterior temporal bottleneck predicted deficits on all tasks, while damage to the anterior bottleneck only significantly predicted deficits in verbal fluency. Importantly, the effects of damage to the bottleneck regions were not attributable to lesion volume, lesion loads on the tracts traversing the bottlenecks, or damage to nearby cortical language areas. Multivariate lesion-symptom mapping revealed additional lesion predictors of deficits. Post-hoc fiber tracking of the peak white matter lesion predictors using a publicly available tractography atlas revealed evidence consistent with the results of the bottleneck analyses. Together, our results provide support for the proposal that spatially specific white matter damage affecting bottleneck regions, particularly in the posterior temporal lobe, contributes to chronic language deficits after left hemispheric stroke. This may reflect the simultaneous disruption of signaling in dorsal and ventral language processing streams.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
One explanation for the constraint is that white matter can act as a bottleneck for multiple processing tracts from multiple neural networks, all of which are affected when the bottleneck is damaged, thereby limiting resources for recovery.
“One explanation for this is that white matter can act as a bottle neck for multiple processing tracts from multiple neural networks, all of which are affected when the bottle neck is damaged, thereby limiting resources for recovery (Griffis et al., 2017).”
From Damage to Broca’s area does not contribute to long-term speech production outcome after stroke (2021) · cites this paper as Griffis et al., 2017
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
Benjamini, Y., & Hochberg, Y. (1995) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1995.tb02031.x · Cited by 109,482 · see citing works
The assessment and analysis of handedness: The Edinburgh inventory
Oldfield, R. C. (1971) · Neuropsychologia · doi:10.1016/0028-3932(71)90067-4 · Cited by 35,900 · see citing works
Statistical parametric maps in functional imaging: A general linear approach
Friston, K. J., Holmes, A. P., Worsley, K. J., Poline, J. ‐., Frith, C. D., & Frackowiak, R. S. J. (1994) · Human Brain Mapping · doi:10.1002/hbm.460020402 · Cited by 9,688 · see citing works
Thresholding of statistical maps in functional neuroimaging using the false discovery rate
Genovese, C. R., Lazar, N. A., & Nichols, T. (2002) · NeuroImage · doi:10.1006/nimg.2001.1037 · Cited by 4,923 · see citing works
Kaplan, E., Goodglass, H., Weıntraub, S., & Segal, O. (2001) · Medical Entomology and Zoology · Cited by 4,378 · see citing works
Automatically Parcellating the Human Cerebral Cortex
Fischl, B. R. (2003) · Cerebral Cortex · doi:10.1093/cercor/bhg087 · Cited by 4,208 · see citing works
Binder, J. R., Desai, R. H., Graves, W. W., & Conant, L. L. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhp055 · Cited by 4,060 · see citing works
Distinct brain networks for adaptive and stable task control in humans
Dosenbach, N. U. F., Fair, D. A., Miezin, F. M., Cohen, A. L., Wenger, K. K., Dosenbach, R. A. T., Fox, M. D., Snyder, A. Z., Vincent, J. L., Raichle, M. E., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0704320104 · Cited by 2,632 · see citing works
Benton, A. (1994) · Annual Review of Psychology · doi:10.1146/annurev.psych.45.1.1 · Cited by 2,298 · see citing works
Price, C. J. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.04.062 · Cited by 2,159 · see citing works
Role of left inferior prefrontal cortex in retrieval of semantic knowledge: A reevaluation
Thompson‐Schill, S. L., D’Esposito, M., Aguirre, G. K., & Farah, M. J. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.26.14792 · Cited by 2,122 · see citing works
The neurobiology of semantic memory
Binder, J. R., & Desai, R. H. (2011) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2011.10.001 · Cited by 2,114 · see citing works
Executive Function and the Frontal Lobes: A Meta-Analytic Review
Alvarez, J. A., & Emory, E. (2006) · Neuropsychology Review · doi:10.1007/s11065-006-9002-x · Cited by 1,981 · see citing works
Meta-analyzing left hemisphere language areas: phonology, semantics, and sentence processing.
Vigneau, M., Beaucousin, V., Hervé, P. Y., Duffau, H., Crivello, F., Houdé, O., Mazoyer, B., & Tzourio-Mazoyer, N. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2005.11.002 · Cited by 1,851 · see citing works
The elusive nature of executive functions: a review of our current understanding.
Jurado, M. B., & Rosselli, M. (2007) · Neuropsychology Review · doi:10.1007/s11065-007-9040-z · Cited by 1,684 · see citing works
A diffusion tensor imaging tractography atlas for virtual in vivo dissections.
CATANI, M., & THIEBAUTDESCHOTTEN, M. (2008) · Cortex · doi:10.1016/j.cortex.2008.05.004 · Cited by 1,642 · see citing works
Virtual in vivo interactive dissection of white matter fasciculi in the human brain
Catani, M., Howard, R. J., Pajevic, S., & Jones, D. K. (2002) · NeuroImage · doi:10.1006/nimg.2002.1136 · Cited by 1,637 · see citing works
Ventral and dorsal pathways for language
Saur, D., Kreher, B. W., Schnell, S., Kümmerer, D., Kellmeyer, P., Vry, M., Umarova, R. M., Musso, M., Glauche, V., Abel, S., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0805234105 · Cited by 1,555 · see citing works
Hua, K., Zhang, J., Wakana, S., Jiang, H., Li, X., Reich, D. S., Calabresi, P. A., Pekar, J. J., van Zijl, P. C. M., & Mori, S. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.07.053 · Cited by 1,507 · see citing works
Voxel-based lesion-symptom mapping
Bates, E., Wilson, S. M., Saygin, A. P., Dick, F., Sereno, M. I., Knight, R. T., & Dronkers, N. F. (2003) · Nature Neuroscience · doi:10.1038/nn1050 · Cited by 1,457 · see citing works
Human Brain Language Areas Identified by Functional Magnetic Resonance Imaging
Binder, J. R., Frost, J. A., Hammeke, T. A., Cox, R. W., Rao, S. M., & Prieto, T. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-01-00353.1997 · Cited by 1,424 · see citing works
The anatomy of language: a review of 100 fMRI studies published in 2009
Price, C. J. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05444.x · Cited by 1,387 · see citing works
Adjusting for multiple testing when reporting research results: the Bonferroni vs Holm methods.
Aickin, M., & Gensler, H. (1996) · American Journal of Public Health · doi:10.2105/ajph.86.5.726 · Cited by 1,346 · see citing works
A new brain region for coordinating speech articulation
Dronkers, N. F. (1996) · Nature · doi:10.1038/384159a0 · Cited by 1,192 · see citing works
Deterministic diffusion fiber tracking improved by quantitative anisotropy
Yeh, F.-C., Verstynen, T. D., Wang, Y., Fernández-Miranda, J. C., & Tseng, W.-Y. I. (2013) · PLoS ONE · doi:10.1371/journal.pone.0080713 · Cited by 1,121 · see citing works
Lesion analysis of the brain areas involved in language comprehension
Dronkers, N. F., Wilkins, D. P., Van Valin, R. D., Redfern, B. B., & Jaeger, J. J. (2004) · Cognition · doi:10.1016/j.cognition.2003.11.002 · Cited by 1,035 · see citing works
Generalized ${ q}$-Sampling Imaging
Yeh, F.-C. F., Wedeen, V. J., & Tseng, W. I. (2010) · IEEE Transactions on Medical Imaging · doi:10.1109/tmi.2010.2045126 · Cited by 1,030 · see citing works
Turken, A. U., & Dronkers, N. F. (2011) · Frontiers in System Neuroscience · doi:10.3389/fnsys.2011.00001 · Cited by 1,012 · see citing works
Catani, M., & Mesulam, M. M. (2008) · Cortex · doi:10.1016/j.cortex.2008.04.002 · Cited by 759 · see citing works
Left inferior frontal gyrus is critical for response inhibition
Swick, D., Ashley, V., & Turken, A. U. (2008) · BMC Neuroscience · doi:10.1186/1471-2202-9-102 · Cited by 745 · see citing works
Friederici, A. D., & Gierhan, S. M. E. (2012) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2012.10.002 · Cited by 673 · see citing works
Baldo, J., Schwartz, S., Wilkins, D., & Dronkers, N. (2006) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617706061078 · Cited by 570 · see citing works
Oishi, K., Zilles, K., Amunts, K., Faria, A. V., Jiang, H., Li, X., Akhter, K., Hua, K., Woods, R. P., Toga, A. W., et al. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.07.009 · Cited by 560 · see citing works
Language lateralization in left-handed and ambidextrous people
Szaflarski, J. P., Binder, J. R., Possing, E. T., McKiernan, K. A., Ward, B. D., & Hammeke, T. A. (2002) · Neurology · doi:10.1212/wnl.59.2.238 · Cited by 538 · see citing works
Language processing is strongly left lateralized in both sexes: Evidence from functional MRI
Frost, J. A. (1999) · Brain · doi:10.1093/brain/122.2.199 · Cited by 537 · see citing works
NTU-90: A high angular resolution brain atlas constructed by q-space diffeomorphic reconstruction
Yeh, F.-C. F., & Tseng, W. I. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.06.021 · Cited by 509 · see citing works
Costafreda, S. G., Fu, C. H. Y., Lee, L., Everitt, B., Brammer, M. J., & David, A. S. (2006) · Human Brain Mapping · doi:10.1002/hbm.20221 · Cited by 496 · see citing works
A novel frontal pathway underlies verbal fluency in primary progressive aphasia
Catani, M., Mesulam, M. M., Jakobsen, E., Malik, F., Martersteck, A., Wieneke, C. A., Thompson, C. K., de Schotten, M. T., Dell’Acqua, F., Weıntraub, S., et al. (2013) · Brain · doi:10.1093/brain/awt163 · Cited by 480 · see citing works
Common Behavioral Clusters and Subcortical Anatomy in Stroke
Corbetta, M., Ramsey, L., Callejas, A., Baldassarre, A., Hacker, C. D., Siegel, J. S., Astafiev, S. V., Rengachary, J., Zinn, K., Lang, C. E., et al. (2015) · Neuron · doi:10.1016/j.neuron.2015.02.027 · Cited by 442 · see citing works
Verbal Fluency: Language or Executive Function Measure?
Whiteside, D. M., Kealey, T., Semla, M., Luu, H., Rice, L., Basso, M. R., & Roper, B. (2016) · Applied Neuropsychology: Adult · doi:10.1080/23279095.2015.1004574 · Cited by 430 · see citing works
Schwartz, M. F., Kimberg, D. Y., Walker, G. M., Faseyitan, O. K., Brecher, A. R., Dell, G. S., & Coslett, H. B. (2009) · Brain · doi:10.1093/brain/awp284 · Cited by 379 · see citing works
Rojkova, K., Volle, E., Urbanski, M., Humbert, F., Dell’Acqua, F., & Thiebaut de Schotten, M. (2016) · Brain Structure and Function · doi:10.1007/s00429-015-1001-3 · Cited by 361 · see citing works
fMRI reveals two distinct cerebral networks subserving speech motor control
Riecker, A., Mathiak, K., Wildgruber, D., Erb, M., Hertrich, I., Grodd, W., & Ackermann, H. (2005) · Neurology · doi:10.1212/01.wnl.0000152156.90779.89 · Cited by 327 · see citing works
Speech Facilitation by Left Inferior Frontal Cortex Stimulation
Holland, R., Leff, A. P., Josephs, O., Galea, J. M., Desikan, M., Price, C. J., Rothwell, J. C., & Crinion, J. (2011) · Current Biology · doi:10.1016/j.cub.2011.07.021 · Cited by 312 · see citing works
Forkel, S. J., de Schotten, M. T., Dell’Acqua, F., Kalra, L., Murphy, D., Williams, S., & Catani, M. (2014) · Brain · doi:10.1093/brain/awu113 · Cited by 305 · see citing works
Multivariate lesion-symptom mapping using support vector regression
Zhang, Y.-S., Kimberg, D. Y., Coslett, H. B., Schwartz, M. F., & Wang, Z. (2014) · Human Brain Mapping · doi:10.1002/hbm.22590 · Cited by 298 · see citing works
Neural organization of spoken language revealed by lesion–symptom mapping
Mirman, D., Chen, Q., Zhang, Y.-S., Wang, Z., Faseyitan, O. K., Coslett, H. B., & Schwartz, M. F. (2015) · Nature Communications · doi:10.1038/ncomms7762 · Cited by 290 · see citing works
Baldo, J. V., Arévalo, A. L., Patterson, J. P., & Dronkers, N. F. (2012) · Cortex · doi:10.1016/j.cortex.2012.03.001 · Cited by 255 · see citing works
Damage to ventral and dorsal language pathways in acute aphasia
Kümmerer, D., Hartwigsen, G., Kellmeyer, P., Glauche, V., Mader, I., Klöppel, S., Suchan, J., Karnath, H., Weiller, C., & Saur, D. (2013) · Brain · doi:10.1093/brain/aws354 · Cited by 255 · see citing works
Almairac, F., Herbet, G., Moritz‐Gasser, S., de Champfleur, N. M., & Duffau, H. (2014) · Brain Structure and Function · doi:10.1007/s00429-014-0773-1 · Cited by 251 · see citing works
Impairment of speech production predicted by lesion load of the left arcuate fasciculus
Marchina, S., Zhu, L. L., Norton, A., Zipse, L., Wan, C. Y., & Schlaug, G. (2011) · Stroke · doi:10.1161/strokeaha.110.606103 · Cited by 230 · see citing works
Ivanova, M. V., Isaev, D. Y., Dragoy, O. V., Akinina, Y. S., Petrushevskiy, A. G., Fedina, O. N., Shklovsky, V. M., & Dronkers, N. F. (2016) · Cortex · doi:10.1016/j.cortex.2016.04.019 · Cited by 221 · see citing works
Butler, R. A., Ralph, M. A. L., & Woollams, A. M. (2014) · Brain · doi:10.1093/brain/awu286 · Cited by 198 · see citing works
A comparison of five fMRI protocols for mapping speech comprehension systems
Binder, J. R., Swanson, S. J., Hammeke, T. A., & Sabsevitz, D. S. (2008) · Epilepsia · doi:10.1111/j.1528-1167.2008.01683.x · Cited by 198 · see citing works
Translation of Broca's 1865 Report
Berker, E. (1986) · Archives of Neurology · doi:10.1001/archneur.1986.00520100069017 · Cited by 192 · see citing works
Fridriksson, J. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.2227-10.2010 · Cited by 174 · see citing works
Damage to the anterior arcuate fasciculus predicts non-fluent speech production in aphasia
Fridriksson, J., Guo, D., Fillmore, P., Holland, A., & Rorden, C. (2013) · Brain · doi:10.1093/brain/awt267 · Cited by 172 · see citing works
Yourganov, G., Fridriksson, J., Rorden, C., Gleichgerrcht, E. L., & Bonilha, L. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.4396-15.2016 · Cited by 170 · see citing works
Harvey, D. Y., & Schnur, T. T. (2015) · Cortex · doi:10.1016/j.cortex.2015.03.004 · Cited by 168 · see citing works
Lu, C., Peng, D., Chen, C., Ning, N., Ding, G., Li, K., Yang, Y., & Lin, C. (2009) · Cortex · doi:10.1016/j.cortex.2009.02.017 · Cited by 167 · see citing works
Word Retrieval Learning Modulates Right Frontal Cortex in Patients with Left Frontal Damage
Blasi, V., Young, A. C., Tansy, A. P., Petersen, S. E., Snyder, A. Z., & Corbetta, M. (2002) · Neuron · doi:10.1016/s0896-6273(02)00936-4 · Cited by 166 · see citing works
A fMRI study of word retrieval in aphasia
Perani, D., Cappa, S. F., Tettamanti, M., Rosa, M. M., Scifo, P., Miozzo, A., Basso, A., & Fazio, F. (2003) · Brain and Language · doi:10.1016/s0093-934x(02)00561-8 · Cited by 166 · see citing works
Walker, G. M., Schwartz, M. F., Kimberg, D. Y., Faseyitan, O. K., Brecher, A. R., Dell, G. S., & Coslett, H. B. (2010) · Brain and Language · doi:10.1016/j.bandl.2010.09.008 · Cited by 157 · see citing works
Griffis, J. C., Allendorfer, J. B., & Szaflarski, J. P. (2016) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2015.09.019 · Cited by 154 · see citing works
Biesbroek, J. M., van Zandvoort, M. J. E., Kappelle, L. J., Velthuis, B. K., Biessels, G. J., & Postma, A. (2015) · Brain Structure and Function · doi:10.1007/s00429-015-1033-8 · Cited by 150 · see citing works
Overlapping Networks Engaged during Spoken Language Production and Its Cognitive Control
Geranmayeh, F., Wise, R. J. S., Mehta, A., & Leech, R. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.0428-14.2014 · Cited by 143 · see citing works
Szaflarski, J. P., Vannest, J. J., Wu, S. W., DiFrancesco, M. W., Banks, C., & Gilbert, D. L. (2011) · Medical Science Monitor · doi:10.12659/msm.881446 · Cited by 143 · see citing works
Henseler, I., Regenbrecht, F., & Obrig, H. (2014) · Brain · doi:10.1093/brain/awt374 · Cited by 143 · see citing works
Kozora, E., & Cullum, C. M. (1995) · The Clinical Neuropsychologist · doi:10.1080/13854049508400495 · Cited by 137 · see citing works
Comprehensive presurgical functional MRI language evaluation in adult patients with epilepsy
Szaflarski, J. P., Holland, S. K., Jacola, L. M., Lindsell, C. J., Privitera, M., & Szaflarski, M. (2007) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2007.07.015 · Cited by 135 · see citing works
Pustina, D., Coslett, H. B., Turkeltaub, P. E., Tustison, N. J., Schwartz, M. F., & Avants, B. (2016) · Human Brain Mapping · doi:10.1002/hbm.23110 · Cited by 135 · see citing works
Intrinsic functional network architecture of human semantic processing: Modules and hubs
Xu, Y., Lin, Q., Han, Z., Yong He, A., & Bi, Y. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2016.03.004 · Cited by 132 · see citing works
Heim, S., Eickhoff, S. B., & Amunts, K. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.06.044 · Cited by 123 · see citing works
Szaflarski, J. P., Allendorfer, J. B., Banks, C., Vannest, J. J., & Holland, S. K. (2013) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-120267 · Cited by 119 · see citing works
Bonilha, L., Gleichgerrcht, E. L., Nesland, T., Rorden, C., & Fridriksson, J. (2015) · Neurorehabilitation and neural repair · doi:10.1177/1545968315593808 · Cited by 113 · see citing works
Functional Magnetic Resonance Imaging Before and After Aphasia Therapy
Peck, K. K., MOORE, A. B., Crosson, B., Gaiefsky, M., Gopinath, K., White, K. D., & Briggs, R. W. (2004) · Stroke · doi:10.1161/01.str.0000110983.50753.9d · Cited by 105 · see citing works
Bizzi, A., Nava, S., Ferrè, F., Castelli, G., Aquino, D., Ciaraffa, F., Broggi, G., DiMeco, F., & Piacentini, S. H. M. J. (2011) · Cortex · doi:10.1016/j.cortex.2011.11.015 · Cited by 99 · see citing works
Mirman, D., Zhang, Y., Wang, Z., Coslett, H. B., & Schwartz, M. F. (2015) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2015.02.014 · Cited by 87 · see citing works
Generating animal and tool names: An fMRI study of effective connectivity
Vitali, P., Abutalebi, J., Tettamanti, M., Rowe, J. B., Scifo, P., Fazio, F., Cappa, S. F., & Perani, D. (2004) · Brain and Language · doi:10.1016/j.bandl.2004.08.005 · Cited by 86 · see citing works
Reading Aloud Boosts Connectivity through the Putamen
Seghier, M. L., & Price, C. J. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhp123 · Cited by 83 · see citing works
Semantic association investigated with functional MRI and independent component analysis
Kim, K. K., Karunanayaka, P., Privitera, M., Holland, S. K., & Szaflarski, J. P. (2011) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2010.11.010 · Cited by 77 · see citing works
Reliability of fMRI for studies of language in post-stroke aphasia subjects
Eaton, K. P., Szaflarski, J. P., Altaye, M., Ball, A. L., D, B. M. K. M., Banks, C., & Holland, S. K. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.02.033 · Cited by 75 · see citing works
Hope, T. M. H., Seghier, M. L., Prejawa, S., Leff, A. P., & Price, C. J. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2015.09.025 · Cited by 64 · see citing works
Chouiter, L., Holmberg, J., Manuel, A. L., Colombo, F., Clarke, S., Annoni, J., & Spierer, L. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.05.029 · Cited by 61 · see citing works
Wang, Y., Yeh, Y.-H., Tsang, S.-M., Liu, W., Shi, H., Li, Z., Shi, Y., Wang, Y., Wang, Y.-N., Lui, S. S. Y., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0061115 · Cited by 60 · see citing works
A comparison of VLSM and VBM in a cohort of patients with post-stroke aphasia
Geva, S., Baron, J., Jones, P. S., Price, C. J., & Warburton, E. A. (2012) · NeuroImage Clinical · doi:10.1016/j.nicl.2012.08.003 · Cited by 58 · see citing works
The canonical semantic network supports residual language function in chronic post‐stroke aphasia
Griffis, J. C., Nenert, R. E., Allendorfer, J. B., Vannest, J. J., Holland, S. K., Dietz, A. R., & Szaflarski, J. P. (2016) · Human Brain Mapping · doi:10.1002/hbm.23476 · Cited by 57 · see citing works
Fama, M. E., Hayward, W., Snider, S. F., Friedman, R. B., & Turkeltaub, P. E. (2016) · Brain and Language · doi:10.1016/j.bandl.2016.09.009 · Cited by 55 · see citing works
Semantic fluency in aphasia: clustering and switching in the course of 1 minute
Bose, A., Wood, R., & Kiran, S. (2016) · International Journal of Language & Communication Disorders · doi:10.1111/1460-6984.12276 · Cited by 50 · see citing works
Thames, A. D., Foley, J. M., Wright, M. J., Panos, S. E., Ettenhofer, M. L., Ramezani, A., Streiff, V., El-Saden, S. M., Goodwin, S., Bookheimer, S. Y., et al. (2011) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2011.12.010 · Cited by 46 · see citing works
Geva, S., Correia, M., & Warburton, E. A. (2015) · Brain and Language · doi:10.1016/j.bandl.2015.09.001 · Cited by 38 · see citing works
Right hemispheric participation in semantic decision improves performance
Donnelly, K. M., Allendorfer, J. B., & Szaflarski, J. P. (2011) · Brain Research · doi:10.1016/j.brainres.2011.08.065 · Cited by 37 · see citing works
Seghier, M. L., Bagdasaryan, J., Jung, D. E., & Price, C. J. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.1954-14.2014 · Cited by 30 · see citing works
Skipper‐Kallal, L. M., Mirman, D., & Olson, I. R. (2015) · Cortex · doi:10.1016/j.cortex.2015.04.021 · Cited by 28 · see citing works
Lau, J. K. L., Humphreys, G. W., Douis, H., Balani, A. B., Bickerton, W., & Rotshtein, P. (2015) · NeuroImage Clinical · doi:10.1016/j.nicl.2015.01.015 · Cited by 22 · see citing works
Correction: Deterministic Diffusion Fiber Tracking Improved by Quantitative Anisotropy
Yeh, F.-C. F., Verstynen, T., Wang, Y., Fernandez-Miranda, J. C., & Tseng, W. I. (2014) · PLoS ONE · doi:10.1371/annotation/0f3b12de-8b8b-4dda-9ff4-835b8631e1dc · Cited by 13 · see citing works
Flagged first, then by citations
1 of the 97 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Advanced lesion symptom mapping analyses and implementation as BCBtoolkit
Foulon, C., Cerliani, L., Kinkingnéhun, S., Lévy, R., Rosso, C., Urbanski, M., Emmanuelle Volle, C., & de Schotten, M. T. (2018) · GigaScience · doi:10.1093/gigascience/giy004 · Cited by 359 · see citing works
Structural disconnections explain brain network dysfunction after stroke
Griffis, J. C., Metcalf, N. V., Corbetta, M., & Shulman, G. L. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.07.100 · Cited by 213 · see citing works
Self-citationZhao, L., Biesbroek, J. M., Shi, L., Liu, W., Kuijf, H. J., Chu, C. W., Abrigo, J., Lee, R. K. L., Leung, T. W. H., Lau, A. Y. L., et al. (2017) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x17728162 · Cited by 208 · see citing works
Improved accuracy of lesion to symptom mapping with multivariate sparse canonical correlations
Pustina, D., Avants, B., Faseyitan, O. K., Medaglia, J. D., & Coslett, H. B. (2017) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2017.08.027 · Cited by 183 · see citing works
Damage to Broca’s area does not contribute to long-term speech production outcome after stroke
Gajardo-Vidal, A., Lorca-Puls, D. L., team, P., Warner, H., Pshdary, B., Crinion, J. T., Leff, A. P., Hope, T. M. H., Geva, S., Seghier, M. L., et al. (2021) · Brain · doi:10.1093/brain/awaa460 · Cited by 150 · see citing works
Griffis, J. C., Metcalf, N. V., Corbetta, M., & Shulman, G. L. (2021) · NeuroImage Clinical · doi:10.1016/j.nicl.2021.102639 · Cited by 140 · see citing works
Functional Contributions of the Arcuate Fasciculus to Language Processing
Ivanova, M. V., Zhong, A. J., Turken, A. U., Baldo, J. V., & Dronkers, N. F. (2021) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2021.672665 · Cited by 108 · see citing works
Post-stroke outcomes predicted from multivariate lesion-behaviour and lesion network mapping
Bowren, M. D., Bruss, J., Manzel, K. W., Edwards, D. J., Liu, C. Y., Corbetta, M., Tranel, D., & Boes, A. D. (2022) · Brain · doi:10.1093/brain/awac010 · Cited by 110 · see citing works
Ivanova, M. V., Herron, T. J., Dronkers, N. F., & Baldo, J. V. (2020) · Human Brain Mapping · doi:10.1002/hbm.25278 · Cited by 79 · see citing works
An empirical evaluation of multivariate lesion behaviour mapping using support vector regression
Sperber, C., Wiesen, D., & Karnath, H. (2018) · Human Brain Mapping · doi:10.1002/hbm.24476 · Cited by 74 · see citing works
Griffis, J. C., Metcalf, N. V., Corbetta, M., & Shulman, G. L. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2020.116589 · Cited by 72 · see citing works
Reber, J., Hwang, K., Bowren, M. D., Bruss, J., Mukherjee, P., Tranel, D., & Boes, A. D. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2018784118 · Cited by 73 · see citing works
Uncovering the Neuroanatomy of Core Language Systems Using Lesion-Symptom Mapping
Mirman, D., & Thye, M. D. (2018) · Current Directions in Psychological Science · doi:10.1177/0963721418787486 · Cited by 61 · see citing works
Shekari, E., & Nozari, N. (2023) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2023.1139292 · Cited by 67 · see citing works
Meier, E. L., Johnson, J. P., Pan, Y., & Kiran, S. (2019) · Brain Imaging and Behavior · doi:10.1007/s11682-019-00118-3 · Cited by 53 · see citing works
Zekelman, L., Zhang, F., Makris, N., He, J., Chen, Y., Xue, T., Liera, D., Drane, D. L., Yogesh Rathi, A., Golby, A. J., et al. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.118739 · Cited by 50 · see citing works
Roles of ventral versus dorsal pathways in language production: An awake language mapping study
Riès, S., Piai, V., Perry, D. W., Griffin, S., Jordan, K., Henry, R. G., Knight, R. T., & Berger, M. S. (2019) · Brain and Language · doi:10.1016/j.bandl.2019.01.001 · Cited by 49 · see citing works
Fluency and rule breaking behaviour in the frontal cortex
Lisa Cipolotti, A., Molenberghs, P., Domínguez, J. F., Smith, N., Smirni, D., Xu, T., Shallice, T., & Chan, E. (2019) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2019.107308 · Cited by 48 · see citing works
Network-behavior mapping of lasting executive impairments after low-grade glioma surgery
Cochereau, J., Lemaitre, A., Wager, M., Moritz‐Gasser, S., Duffau, H., & Herbet, G. (2020) · Brain Structure and Function · doi:10.1007/s00429-020-02131-5 · Cited by 47 · see citing works
Wiesen, D., Sperber, C., Yourganov, G., Rorden, C., & Karnath, H. (2019) · NeuroImage · doi:10.1016/j.neuroimage.2019.07.013 · Cited by 45 · see citing works
Szaflarski, J. P., Griffis, J. C., Vannest, J. J., Allendorfer, J. B., Nenert, R. E., Amara, A. W., Sung, V., Walker, H. C., Martin, A. N., Mark, V. W., et al. (2018) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-180812 · Cited by 42 · see citing works
Bice, A. R., Xiao, Q., Kong, J., Yan, P., Rosenthal, Z. P., Kraft, A. W., Smith, K. P., Wieloch, T. W., Lee, J., Culver, J. P., et al. (2022) · eLife · doi:10.7554/elife.68852 · Cited by 36 · see citing works
Multivariate Lesion-Behavior Mapping of General Cognitive Ability and Its Psychometric Constituents
Bowren, M. D., Adolphs, R., Bruss, J., Manzel, K. W., Corbetta, M., Tranel, D., & Boes, A. D. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.1415-20.2020 · Cited by 37 · see citing works
Longitudinal fMRI study of language recovery after a left hemispheric ischemic stroke
Nenert, R. E., Allendorfer, J. B., Martin, A. M., Banks, C., Vannest, J. J., Holland, S. K., Hart, K. W., Lindsell, C. J., & Szaflarski, J. P. (2018) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-170767 · Cited by 39 · see citing works
Mapping articulatory and grammatical subcomponents of fluency deficits in post-stroke aphasia
Mirman, D., Kraft, A. E., Harvey, D. Y., Brecher, A. R., & Schwartz, M. F. (2019) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-019-00729-9 · Cited by 37 · see citing works
Lesion network mapping: where do we go from here?
Boes, A. D. (2020) · Brain · doi:10.1093/brain/awaa350 · Cited by 36 · see citing works
Billot, A., de Schotten, M. T., Parrish, T. B., Thompson, C. K., Rapp, B. C., Caplan, D. N., & Kiran, S. (2022) · Cortex · doi:10.1016/j.cortex.2022.06.016 · Cited by 33 · see citing works
Szaflarski, J. P., Nenert, R. E., Allendorfer, J. B., Martin, A. N., Amara, A. W., Griffis, J. C., Dietz, A. R., Mark, V. W., Sung, V., Walker, H. C., et al. (2021) · Medical Science Monitor · doi:10.12659/msm.931468 · Cited by 34 · see citing works
The unique role of the frontal aslant tract in speech and language processing
Zhong, A. J., Baldo, J. V., Dronkers, N. F., & Ivanova, M. V. (2022) · NeuroImage Clinical · doi:10.1016/j.nicl.2022.103020 · Cited by 32 · see citing works
Griffis, J. C., Nenert, R. E., Allendorfer, J. B., & Szaflarski, J. P. (2017) · Cortex · doi:10.1016/j.cortex.2017.08.031 · Cited by 33 · see citing works
Meier, E. L., Johnson, J. P., & Kiran, S. (2018) · Cortex · doi:10.1016/j.cortex.2018.08.006 · Cited by 32 · see citing works
A Review on Treatment-Related Brain Changes in Aphasia
Schevenels, K., Price, C. J., Zink, I., Smedt, B. D., & Vandermosten, M. (2020) · Neurobiology of Language · doi:10.1162/nol_a_00019 · Cited by 32 · see citing works
Camerino, I., Sierpowska, J., Reid, A., Meyer, N. H., Tuladhar, A. M., Kessels, R. P. C., de Leeuw, F., & Piai, V. (2020) · Human Brain Mapping · doi:10.1002/hbm.25273 · Cited by 32 · see citing works
Piai, V., & Eikelboom, D. (2023) · Neurobiology of Language · doi:10.1162/nol_a_00097 · Cited by 31 · see citing works
Sperber, C., Wiesen, D., Goldenberg, G., & Karnath, H. (2019) · Cortex · doi:10.1016/j.cortex.2019.08.023 · Cited by 31 · see citing works
The emergence of multiscale connectomics-based approaches in stroke recovery
Latifi, S., & Carmichael, S. T. (2024) · Trends in Neurosciences · doi:10.1016/j.tins.2024.01.003 · Cited by 28 · see citing works
Wiesen, D., Karnath, H., & Sperber, C. (2020) · Cortex · doi:10.1016/j.cortex.2020.09.012 · Cited by 28 · see citing works
Prediction of Aphasia Severity in Patients with Stroke Using Diffusion Tensor Imaging
Lee, J.-K., Ko, M.-H., Park, S.-H., & Kim, G.-W. (2021) · Brain Sciences · doi:10.3390/brainsci11030304 · Cited by 26 · see citing works
The entire brain, more or less, is at work : 'Language regions' are artefacts of averagingPreprint
Aliko, S., Franch, M., Kewenig, V. N., Wang, B., Cooper, G. J., Glotfelty, A., Hayden, B. Y., Small, S. L., & Skipper, J. I. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.09.01.555886 · Cited by 29 · see citing works
Halai, A. D., Woollams, A. M., & Ralph, M. A. L. (2018) · NeuroImage Clinical · doi:10.1016/j.nicl.2018.03.011 · Cited by 24 · see citing works
Geller, J., Thye, M. D., & Mirman, D. (2019) · NeuroImage · doi:10.1016/j.neuroimage.2019.01.020 · Cited by 25 · see citing works
The white matter architecture underlying semantic processing: A systematic review
Cocquyt, E., Lanckmans, E., van Mierlo, P., Duyck, W., Szmalec, A., Santens, P., & Letter, M. D. (2019) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2019.107182 · Cited by 23 · see citing works
Dissociable contributions of frontal and temporal brain regions to basic semantic composition
Graessner, A., Zaccarella, E., Friederici, A. D., Obrig, H., & Hartwigsen, G. (2021) · Brain Communications · doi:10.1093/braincomms/fcab090 · Cited by 21 · see citing works
Joint impact on attention, alertness and inhibition of lesions at a frontal white matter crossroad
Kaufmann, B. C., Cazzoli, D., Pastore‐Wapp, M., Vanbellingen, T., Pflugshaupt, T., Bauer, D., Müri, R. M., Nef, T., Bartolomeo, P., & Nyffeler, T. (2022) · Brain · doi:10.1093/brain/awac359 · Cited by 19 · see citing works
A general role for ventral white matter pathways in morphological processing: Going beyond reading
Yablonski, M., Menashe, B. A., & Ben‐Shachar, M. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2020.117577 · Cited by 16 · see citing works
Röhrig, L., Sperber, C., Bonilha, L., Rorden, C., & Karnath, H. (2022) · NeuroImage Clinical · doi:10.1016/j.nicl.2022.103265 · Cited by 16 · see citing works
Language Neuroplasticity in Brain Tumor Patients Revealed by Magnetoencephalography
Piai, V., Witte, E. D., Sierpowska, J., Zheng, X., Hinkley, L. B. N., Mizuiri, D., Knight, R. T., Berger, M. S., & Nagarajan, S. S. (2020) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_01561 · Cited by 16 · see citing works
Meier, E. L., Sheppard, S. M., Goldberg, E. B., Head, C. R., Ubellacker, D. M., Walker, A., & Hillis, A. E. (2020) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2020.107651 · Cited by 17 · see citing works
Independent contributions of structural and functional connectivity: Evidence from a stroke model
Keator, L. M., Yourganov, G., Basilakos, A., Hillis, A. E., Hickok, G. S., Bonilha, L., Rorden, C., & Fridriksson, J. (2021) · Network Neuroscience · doi:10.1162/netn_a_00207 · Cited by 13 · see citing works
Four dimensions of naturalistic language production in aphasia after stroke
Casilio, M., Kasdan, A. V., Bryan, K. M., Shibata, K., Schneck, S. M., Levy, D. F., Entrup, J. L., Onuscheck, C. F., de Riesthal, M. R., & Wilson, S. M. (2024) · Brain · doi:10.1093/brain/awae195 · Cited by 12 · see citing works
Multivariate machine learning‐based language mapping in glioma patients based on lesion topography
Zhang, N., Yuan, B., Yan, J., Cheng, J., Lu, J., & Wu, J. (2021) · Brain Imaging and Behavior · doi:10.1007/s11682-021-00457-0 · Cited by 12 · see citing works
Suárez-Meade, P., Marenco-Hillembrand, L., Sabsevitz, D. S., Okromelidze, L., Perdikis, B., Sherman, W. J., Quiñones‐Hinojosa, A., Middlebrooks, E. H., & Chaichana, K. L. (2022) · Clinical Neurology and Neurosurgery · doi:10.1016/j.clineuro.2022.107512 · Cited by 12 · see citing works
Garcea, F. E., & Buxbaum, L. J. (2022) · Cortex · doi:10.1016/j.cortex.2023.06.012 · Cited by 11 · see citing works
Multivariate lesion symptom mapping for predicting trajectories of recovery from aphasia
Levy, D. F., Entrup, J. L., Schneck, S. M., Onuscheck, C. F., Rahman, M., Kasdan, A. V., Casilio, M., Willey, E., Davis, L. T., de Riesthal, M. R., et al. (2023) · Brain Communications · doi:10.1093/braincomms/fcae024 · Cited by 13 · see citing works
Griffis, J. C., Bruss, J., Acker, S. F., Shea, C., Tranel, D., & Boes, A. D. (2024) · Human Brain Mapping · doi:10.1002/hbm.70115 · Cited by 11 · see citing works
Perioperative Neurocognitive Function in Glioma Surgery
Noll, K. R., Bradshaw, M. E., Sheppard, D. P., & Wefel, J. S. (2024) · Current Oncology Reports · doi:10.1007/s11912-024-01522-9 · Cited by 10 · see citing works
Lewis, L., Corcoran, M., Cho, K. I. K., Kwak, Y., Hayes, R. A., Larsen, B., & Jalbrzikowski, M. (2023) · Schizophrenia · doi:10.1038/s41537-023-00411-7 · Cited by 9 · see citing works
León-Cabrera, P., Pagonabarraga, J., Morís, J., Martínez‐Horta, S., Marín‐Lahoz, J., Horta‐Barba, A., Bejr‐Kasem, H., Kulisevsky, J., & Rodríguez‐Fornells, A. (2021) · Cortex · doi:10.1016/j.cortex.2021.03.032 · Cited by 9 · see citing works
Chupina, I., Sierpowska, J., Zheng, X., Dewenter, A., Piastra, M. C., & Piai, V. (2022) · European Journal of Neuroscience · doi:10.1111/ejn.15813 · Cited by 8 · see citing works
Selecting and Analyzing Speech Features for the Screening of Mild Cognitive Impairment
Yang, Q., Xu, F., Ling, Z.-H., Li, X., Li, Y., & Fang, D. (2021) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc46164.2021.9630752 · Cited by 8 · see citing works
Coran, M., Rodríguez‐Fornells, A., Ramos‐Escobar, N., Laine, M., & Martin, N. (2020) · Topics in Language Disorders · doi:10.1097/tld.0000000000000204 · Cited by 8 · see citing works
Vadinova, V., Sihvonen, A. J., Wee, F., Garden, K. L., Ziraldo, L., Roxbury, T., O’Brien, K. M., Copland, D. A., McMahon, K. L., & Brownsett, S. L. E. (2024) · Human Brain Mapping · doi:10.1002/hbm.26568 · Cited by 6 · see citing works
Low, T. A., Chilvers, M. J., Zhu, H., Carlson, H. L., Harris, A. D., Goodyear, B. G., & Dukelow, S. P. (2024) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2024.123065 · Cited by 5 · see citing works
The effect of venlafaxine on language function in patients with subcortical aphasia
Wang, L., Li, C., Liu, L., Zhang, W., & Liu, Y. (2025) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2025.04.015 · Cited by 4 · see citing works
Fujioka, T., Freigang, C., Honjo, K., Chen, J., Chen, J. L., Black, S., Stuss, D. T., Dawson, D., & Ross, B. (2020) · Clinical Neurophysiology · doi:10.1016/j.clinph.2020.01.014 · Cited by 4 · see citing works
Brzus, M., Griffis, J. C., Riley, C. J., Bruss, J., Shea, C., Johnson, H. J., & Boes, A. D. (2026) · npj Digital Medicine · doi:10.1038/s41746-026-02803-2 · Cited by 4 · see citing works
Preoperative Brain Mapping Predicts Language Outcomes After Eloquent Tumor Resection
Muir, M. T., Noll, K. R., Prinsloo, S., Michener, H., Traylor, J. I., Kumar, V. A., Ene, C., Ferguson, S. D., Liu, H., Weinberg, J. S., et al. (2025) · Human Brain Mapping · doi:10.1002/hbm.70340 · Cited by 3 · see citing works
Preserved anatomical bypasses predict variance in language functions after stroke
Erickson, B. A., Kim, B., Deck, B. L., Pustina, D., DeMarco, A. T., Dickens, J. V., Kelkar, A. S., Turkeltaub, P. E., & Medaglia, J. D. (2022) · Cortex · doi:10.1016/j.cortex.2022.05.023 · Cited by 3 · see citing works
Tilwani, D., O’Reilly, C., Riccardi, N., Shalin, V. L., den Ouden, D., Shinkareva, S. V., Fridriksson, J., Sheth, A., & Desai, R. H. (2025) · Frontiers in Neuroimaging · doi:10.3389/fnimg.2025.1573816 · Cited by 3 · see citing works
Language neuroplasticity in brain tumour patients revealed by magnetoencephalographyPreprint
Piai, V. (2019) · doi:10.31234/osf.io/uqxkg · Cited by 2 · see citing works
Yu, Q., & Qian, W. (2022) · Brain Sciences · doi:10.3390/brainsci12091253 · Cited by 1 · see citing works
Shekari, E., & Nozari, N. (2022) · doi:10.31234/osf.io/kwf4r · Cited by 1 · see citing works
Teghipco, A., Kim, H., Rorden, C., Newman‐Norlund, R., Sharif, M. S., Sikorski, D., & Hillis, A. E. (2023) · medRxiv · doi:10.1101/2023.09.13.23295370 · Cited by 1 · see citing works
Riès, S., Riès, S., Piai, V., Perry, D. W., Griffin, S., Jordan, K., Knight, R. T., & Berger, M. S. (2017) · Frontiers in Human Neuroscience · doi:10.3389/conf.fnhum.2017.223.00076
Puls, L., & Diego, L. (2019) · UCL Discovery (University College London)
León-Cabrera, P., Pagonabarraga, J., Morís, J., Martínez‐Horta, S., Marín‐Lahoz, J., Horta‐Barba, A., Bejr‐Kasem, H., Kulisevsky, J., & Rodríguez‐Fornells, A. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.11.23.392647
Suárez-Meade, P., Marenco-Hillembrand, L., Sabsevitz, D. S., Okromelidze, L., Perkidis, B., Sherman, W. J., Quiñones‐Hinojosa, A., Middlebrooks, E. H., & Chaichana, K. L. (2021) · Research Square · doi:10.21203/rs.3.rs-788969/v1
Glass Half Full: Preserved Anatomical Bypasses Predict Variance in Language Functions After StrokePreprint
Erickson, B. A., Kim, B., Deck, B. L., Pustina, D., DeMarco, A. G., Dickens, J. V., Kelkar, A. S., Turkeltaub, P. E., & Medaglia, J. D. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.08.31.458462
Higashiyama, Y., Kuroki, M., Kudo, Y., Hamada, T., Morihara, K., Saito, A., Miyaji, Y., Kimura, K., Joki, H., Kishida, H., et al. (2023) · Brain Communications · doi:10.1093/braincomms/fcad053
Age-associated alterations in thalamocortical structural connectivity in psychosis-spectrum youthsPreprint
Lewis, L., Corcoran, M., Cho, K. I. K., Kwak, Y., Hayes, R. A., & Jalbrzikowski, M. (2023) · medRxiv · doi:10.1101/2023.07.10.23292446
Moulton, E. J. (2019) · theses.fr (ABES) · doi:10.70675/18d80f29zd496z442dz89c6z78820fe340bf
Causal dependencies between frontal and temporal lobe regions underlying word search and retrievalPreprint
Winzer, B. M., Burns, W., Chikoti, R., Strawderman, E., Meyers, S. P., Walter, K. A., Pilcher, W. H., Tivarus, M. E., Mahon, B. Z., & Garcea, F. E. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.05.20.726706
A case report of crossed aphasia, grasping, and intermanual conflict with the left hand
Sakamoto, F., Kodani, Y., Nakamura, K., & Fukunaga, S. (2026) · Neurocase · doi:10.1080/13554794.2026.2676581
The interacting language network: A framework for neuromodulation and clinical translation
Preisig, B. C., Proix, T., Borghesani, V., Brem, S., Marchesotti, S., & Guggisberg, A. G. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2026.106972
Li, C., Liu, L., Wang, L., Zhang, W., Liu, L., Xie, Q., & Liu, Y. (2026) · Brain Injury · doi:10.1080/02699052.2026.2748375
- Authors
- Griffis, J. C., Nenert, R., Allendorfer, J. B., & Szaflarski, J. P.
- Affiliations
- University of Alabama at Birmingham (US)
- Corresponding author
- Griffis, Joseph C.
- Venue
- NeuroImage Clinical
- Publisher
- Elsevier BV
- Published
- 2017
- Volume
- 14
- Pages
- 552-565
- ISSN
- 2213-1582 (ISSN-L)
- PMC
- PMC5350568
- OpenAlex
- W2519305849
- Cited by
- 87
- References
- 97
- Citations by year
- 2026: 6 · 2025: 3 · 2024: 6 · 2023: 8 · 2022: 12 · 2021: 13 · 2020: 15 · 2019: 12 · 2018: 8 · 2017: 4
- FWCI
- 6.12
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- NeuroImage Clinical (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- arXiv (Cornell University) (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- arXiv (Cornell University)
- Funders
- National Institutes of Health (NIH R01 HD068488, NIH R01 NS048281)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hemispheric Asymmetry in Neuroscience
- Keywords
- left hemispheric stroke, language deficits, posterior temporal lobe, semantic deficits, verbal fluency, picture naming, thalamocortical connections, lesion-symptom mapping, tractography, chronic stroke
- MeSH terms
- Adult, Aged, Brain Mapping, Decision Making, Female, Humans, Image Processing, Computer-Assisted, Language Disorders, Language Tests, Functional Laterality, Magnetic Resonance Imaging, Male, Middle Aged, Regression Analysis, Semantics, Verbal Behavior, Stroke, White Matter
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
