Cited by 1,033Sex and Gender in HealthcarePain Mechanisms and TreatmentsPain Management and Opioid Use

The DOI matches its Crossref record; 224 of the 224 references it cites were found in a registry or an index.

Studying sex and gender differences in pain and analgesia: A consensus report

Open access

Greenspan, Joel D., Craft, Rebecca M., LeResche, Linda, Arendt-Nielsen, Lars, Berkley, Karen J., Fillingim, Roger B., Gold, Michael S., Holdcroft, Anita, Lautenbacher, Stefan, Mayer, Emeran A., Mogil, Jeffrey S., Murphy, Anne Z., Traub, Richard J.·2007·Pain

DOI 10.1016/j.pain.2007.10.014PMC PMC2823483

Open this paper in CoChat — free account

Abstract

In September 2006, members of the Sex, Gender and Pain Special Interest Group of the International Association for the Study of Pain met to discuss the following: (1) what is known about sex and gender differences in pain and analgesia; (2) what are the "best practice" guidelines for pain research with respect to sex and gender; and (3) what are the crucial questions to address in the near future? The resulting consensus presented herein includes input from basic science, clinical and psychosocial pain researchers, as well as from recognized experts in sexual differentiation and reproductive endocrinology. We intend this document to serve as a utilitarian and thought-provoking guide for future research on sex and gender differences in pain and analgesia, both for those currently working in this field as well as those still wondering, "Do I really need to study females?"

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.pain.2007.10.014

Cites

224 of 224 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The Physiology of Reproduction
Legendre, M., & Jalabert, B. (1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-109-2-176_1 · Cited by 7,876
Grading the severity of chronic pain
Von Korff, M., Ormel, J., Keefe, F. J., & Dworkin, S. F. (1992) · Pain · doi:10.1016/0304-3959(92)90154-4 · Cited by 3,022
Sex differences in HPA axis responses to stress: a review
Kudielka, B. M., & Kirschbaum, C. (2005) · Biological Psychology · doi:10.1016/j.biopsycho.2004.11.009 · Cited by 1,624
Gender variations in clinical pain experience
Unruh, A. M. (1996) · Pain · doi:10.1016/0304-3959(95)00214-6 · Cited by 1,550
Sex differences in pain
Berkley, K. J. (1997) · Behavioral and Brain Sciences · doi:10.1017/s0140525x97221485 · Cited by 1,125
Self-citation
Sex differences in the perception of noxious experimental stimuli: a meta-analysis
Riley, J. L., Robinson, M. E., Wise, E. A., Myers, C. D., & Fillingim, R. B. (1998) · Pain · doi:10.1016/s0304-3959(97)00199-1 · Cited by 1,085
VARIATION OF THE HUMAN MENSTRUAL CYCLE THROUGH REPRODUCTIVE LIFE
TRELOAR, A. E., BOYNTON, R. E., BEHN, B. G., & BROWN, B. W. (1968) · Obstetrical & Gynecological Survey · doi:10.1097/00006254-196801000-00019 · Cited by 1,018
An epidemiologic comparison of pain complaints
Korff, M. V., Dworkin, S. F., LeResche, L., & Kruger, A. (1988) · Pain · doi:10.1016/0304-3959(88)90066-8 · Cited by 966
Self-citation
Pharmacologic Analysis of Drug Receptor Interaction
Kenakin, K. T. (1988) · Therapeutic Drug Monitoring · doi:10.1097/00007691-198803000-00029 · Cited by 932
Social Modulation of Pain as Evidence for Empathy in Mice
Langford, D. J., Crager, S. E., Shehzad, Z., Smith, S. B., Sotocinal, S. G., Levenstadt, J. S., Chanda, M. L., Levitin, D. J., & Mogil, J. S. (2006) · Science · doi:10.1126/science.1128322 · Cited by 865
Self-citation
Physiological properties of unmyelinated fiber projection to the spinal cord
Mendell, L. M. (1966) · Experimental Neurology · doi:10.1016/0014-4886(66)90068-9 · Cited by 844
Strategies and Methods for Research on Sex Differences in Brain and Behavior
Becker, J. B., Arnold, A. P., Berkley, K. J., Blaustein, J. D., Eckel, L. A., Hampson, E., Herman, J. P., Marts, S. A., Sadée, W., Steiner, M. S., et al. (2004) · Endocrinology · doi:10.1210/en.2004-1142 · Cited by 833
Self-citation
Abnormal sensitization and temporal summation of second pain (wind-up) in patients with fibromyalgia syndrome
Staud, R., Vierck, C. J., Cannon, R. L., Mauderli, A. P., & Price, D. D. (2001) · Pain · doi:10.1016/s0304-3959(00)00432-2 · Cited by 774
The relationship of gender to pain, pain behavior, and disability in osteoarthritis patients: the role of catastrophizing
Keefe, F. J., Lefebvre, J. C., Egert, J. R., Affleck, G., Sullivan, M. J., & Caldwell, D. S. (2000) · Pain · doi:10.1016/s0304-3959(00)00296-7 · Cited by 735
Gender Differences in Treatment Response to Sertraline Versus Imipramine in Chronic Depression
Kornstein, S. G., Schatzberg, A. F., Thase, M. E., Yonkers, K. A., McCullough, J. P., Keitner, G. I., Gelenberg, A. J., Thomas, S., Harrison, W. M., & Keller, M. B. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.9.1445 · Cited by 712
Exploring the Biological Contributions to Human Health
Institute of Medicine (2001) · National Academies Press eBooks · doi:10.17226/10028 · Cited by 658
Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017α and P450 aromatase localized in neurons
Hojo, Y., Hattori, T.-A., Enami, T., Furukawa, A., Suzuki, K., Ishii, H.-T., Mukai, H., Morrison, J. H., Janssen, W. G. M., Kominami, S., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2630225100 · Cited by 644
Sex differences in pain perception
Wiesenfeld‐Hallin, Z. (2005) · Gender Medicine · doi:10.1016/s1550-8579(05)80042-7 · Cited by 606
Prevalence of Frequent Headache in a Population Sample
Scher, I., Stewart, W. F., Liberman, J. N., & Lipton, R. B. (1998) · Headache The Journal of Head and Face Pain · doi:10.1046/j.1526-4610.1998.3807497.x · Cited by 604
Hypothalamic integration of central and peripheral clocks
Buijs, R. M., & Kalsbeek, A. (2001) · Nature reviews. Neuroscience · doi:10.1038/35081582 · Cited by 601
Factors predisposing women to chronic pelvic pain: systematic review
Latthe, P. M., Mignini, L. E., Gray, R. G., Hills, R. K., & Khan, K. S. (2006) · BMJ · doi:10.1136/bmj.38748.697465.55 · Cited by 591
A meta-analytic review of pain perception across the menstrual cycle
Riley, J. L., Robinson, M. E., Wise, E. A., & Price, D. D. (1999) · Pain · doi:10.1016/s0304-3959(98)00258-9 · Cited by 591
Prevalence of gastrointestinal symptoms six months after bacterial gastroenteritis and risk factors for development of the irritable bowel syndrome: postal survey of patients
Neal, K. R., Hebden, J., & Spiller, R. (1997) · BMJ · doi:10.1136/bmj.314.7083.779 · Cited by 586
Sex differences in pain and analgesia: the role of gonadal hormones
Craft, R. M., Mogil, J. S., & Aloisi, A. M. (2004) · European Journal of Pain · doi:10.1016/j.ejpain.2004.01.003 · Cited by 570
Self-citation
Sex Differences in Pharmacokinetics and Pharmacodynamics
Gandhi, M., Aweeka, F. T., Greenblatt, R. M., & Blaschke, T. F. (2004) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.44.101802.121453 · Cited by 546
Possible Deficiencies of Pain Modulation in Fibromyalgia
Lautenbacher, S., & Rollman, G. B. (1997) · Clinical Journal of Pain · doi:10.1097/00002508-199709000-00003 · Cited by 546
Self-citation
Modulatory influence on somatosensory perception from vibration and heterotopic noxious conditioning stimulation (HNCS) in fibromyalgia patients and healthy subjects
Kosek, E., & Hansson, P. T. (1997) · Pain · doi:10.1016/s0304-3959(96)03295-2 · Cited by 539
The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans
Mogil, J. S., Wilson, S. G., Chesler, E. J., Rankin, A. L., Nemmani, K. V. S., Lariviere, W. R., Groce, M. K., Wallace, M. R., Kaplan, L., Staud, R. M., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0730053100 · Cited by 528
Self-citation
Validity of self-report measures of girls' pubertal status
Brooks-Gunn, J., Warren, M. P., Rosso, J., & Gargiulo, J. (1987) · Child Development · doi:10.2307/1130220 · Cited by 513
A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits
De Vries, G. J., Rissman, E. F., Simerly, R. B., Yang, L.-Y., Scordalakes, E. M., Auger, C. J., Swain, A., Lovell-Badge, R., Burgoyne, P. S., & Arnold, A. P. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-20-09005.2002 · Cited by 509
Diverse Actions of Ovarian Steroids in the Serotonin Neural System
Bethea, C. L., Lu, N. Z., Gundlah, C., & Streicher, J. M. (2002) · Frontiers in Neuroendocrinology · doi:10.1006/frne.2001.0225 · Cited by 497
Minireview: sex differences in adult and developing brains: compensation, compensation, compensation
De Vries, G. J. (2004) · Endocrinology · doi:10.1210/en.2003-1504 · Cited by 486
Tegaserod, a 5‐HT4 receptor partial agonist, relieves symptoms in irritable bowel syndrome patients with abdominal pain, bloating and constipation
Müller-Lissner, S. A., Fumagalli, I. A. L., Bardhan, K. D., Pace, F., Pecher, E., Nault, B., & Rüegg, P. C. (2001) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2001.01094.x · Cited by 462
Gender role expectations of pain: relationship to sex differences in pain
Robinson, M. E., Riley, J. L., Myers, C. D., Papas, R. K., Wise, E. A., Waxenberg, L. B., & Fillingim, R. B. (2001) · The Journal of Pain · doi:10.1054/jpai.2001.24551 · Cited by 423
Self-citation
Hippocampal Synapses Depend on Hippocampal Estrogen Synthesis
Kretz, O., Fester, L., Wehrenberg, U., Zhou, L., Brauckmann, S., Zhao, S., Prange‐Kiel, J., Naumann, T., Jarry, H., Frotscher, M., et al. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.5186-03.2004 · Cited by 417
Changes in temporomandibular pain and other symptoms across the menstrual cycle
LeResche, L., Mancl, L., Sherman, J. J., Gandara, B., & Dworkin, S. F. (2003) · Pain · doi:10.1016/j.pain.2003.06.001 · Cited by 415
Self-citation
Hypogonadism in men consuming sustained-action oral opioids
Daniell, H. W. (2002) · The Journal of Pain · doi:10.1054/jpai.2002.126790 · Cited by 401
Pronociceptive and Antinociceptive Effects of Estradiol through Endogenous Opioid Neurotransmission in Women
Smith, Y. R., Stohler, C. S., Nichols, T. E., Bueller, J. A., Koeppe, R. A., & Zubieta, J. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.5223-05.2006 · Cited by 386
Diffuse noxious inhibitory controls (DNIC) attenuate temporal summation of second pain in normal males but not in normal females or fibromyalgia patients
Staud, R. M., Robinson, M. E., Vierck, C. J., & Price, D. D. (2002) · Pain · doi:10.1016/s0304-3959(02)00325-1 · Cited by 383
Temporal summation of pain from mechanical stimulation of muscle tissue in normal controls and subjects with fibromyalgia syndrome
Staud, R. M., Cannon, R. L., Mauderli, A. P., Robinson, M. E., Price, D. D., & Vierck, C. J. (2003) · Pain · doi:10.1016/s0304-3959(02)00344-5 · Cited by 379
The case for the inclusion of female subjects in basic science studies of pain
Mogil, J. S., & Chanda, M. L. (2005) · Pain · doi:10.1016/j.pain.2005.06.020 · Cited by 376
Self-citation
The effects of experimenter gender on pain report in male and female subjects
Levine, F. M., & Simone, L. L. D. (1991) · Pain · doi:10.1016/0304-3959(91)90149-r · Cited by 369
Sensitivity of patients with painful temporomandibular disorders to experimentally evoked pain: evidence for altered temporal summation of pain
Maixner, W. D., Fillingim, R. B., Sigurðsson, Á., Kincaid, S., & Silva, S. (1998) · Pain · doi:10.1016/s0304-3959(98)00028-1 · Cited by 367
Self-citation
Improvement in pain and bowel function in female irritable bowel patients with alosetron, a 5‐HT3 receptor antagonist
Camilleri, Mayer, Drossman, Heath, Dukes, McSorley, D., Kong, Mangel, A. W., & Northcutt (1999) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.1999.00610.x · Cited by 365
μ-Opioid Receptor-Mediated Antinociceptive Responses Differ in Men and Women
Zubieta, J.-K., Smith, Y. R., Bueller, J. A., Xu, Y., Kilbourn, M. R., Jewett, D. M., Meyer, C. R., Koeppe, R. A., & Stohler, C. S. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-12-05100.2002 · Cited by 363
Sex Differences in Morphine Analgesia
Sarton, E. Y., Olofsen, E., Romberg, R. R., den Hartigh, J., Kest, B., Nieuwenhuijs, D. J. F., Burm, A. G. L., Teppema, L. J., & Dahan, A. (2000) · Anesthesiology · doi:10.1097/00000542-200011000-00018 · Cited by 360
Gender role expectations of pain: relationship to experimental pain perception
Wise, E. A., Price, D. D., Myers, C. D., Heft, M. W., & Robinson, M. E. (2002) · Pain · doi:10.1016/s0304-3959(01)00473-0 · Cited by 359
Side effects of opioids during short-term administration: effect of age, gender, and race
Cepeda, M. (2003) · Clinical Pharmacology & Therapeutics · doi:10.1016/s0009-9236(03)00152-8 · Cited by 352
Sex differences in thermal nociception and morphine antinociception in rodents depend on genotype
Mogil, J. S., Chesler, E. J., Wilson, S. G., Juraska, J. M., & Sternberg, W. F. (2000) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(00)00015-4 · Cited by 346
Self-citation
Circhoral Oscillations of Plasma LH Levels in the Ovariectomized Rhesus Monkey 1 , 2
Dierschke, D. J., Bhattacharya, A. N., Atkinson, L. E., & Knobil, E. (1970) · Endocrinology · doi:10.1210/endo-87-5-850 · Cited by 343
Direct Regulation of Adult Brain Function by the Male-Specific Factor SRY
Dewing, P., Chiang, C. W. K., Sinchak, K., Sim, H., Fernagut, P., Kelly, S., Chesselet, M.-F., Micevych, P. E., Albrecht, K. H., Harley, V. R., et al. (2006) · Current Biology · doi:10.1016/j.cub.2006.01.017 · Cited by 340
Cyclic estradiol treatment normalizes body weight and restores physiological patterns of spontaneous feeding and sexual receptivity in ovariectomized rats.
Asarian, L., & Geary, N. (2002) · Hormones and Behavior · doi:10.1006/hbeh.2002.1835 · Cited by 336
Epidemiology of pain
Macfarlane, G. J., Jones, G. T., & McBeth, J. (2006) · Elsevier eBooks · doi:10.1016/b0-443-07287-6/50081-3 · Cited by 335
First onset of common pain symptoms: a prospective study of depression as a risk factor
Von Korff, M., Resche, L. L., & Dworkin, S. F. (1993) · Pain · doi:10.1016/0304-3959(93)90154-h · Cited by 334
Sex Differences in Opioid Analgesia: “From Mouse to Man”
Craft, R. M. (2003) · Clinical Journal of Pain · doi:10.1097/00002508-200305000-00005 · Cited by 319
Self-citation
Characteristics of second pain and flexion reflexes indicative of prolonged central summation
Price, D. D. (1972) · Experimental Neurology · doi:10.1016/0014-4886(72)90081-7 · Cited by 298
EPIDEMIOLOGY OF INTERSTITIAL CYSTITIS: A POPULATION BASED STUDY
Curhan, G. C., Speizer, F. E., Hunter, D. J., et al. (1999) · The Journal of Urology · doi:10.1016/s0022-5347(01)61947-5 · Cited by 290
Sex differences in temporal summation but not sensory-discriminative processing of thermal pain
Fillingim, R. B., Maixner, W., Kincaid, S., & Silva, S. (1998) · Pain · doi:10.1016/s0304-3959(97)00214-5 · Cited by 289
Self-citation
Relationship of pain and symptoms to pubertal development in adolescents
LeResche, L., Mancl, L., Drangsholt, M. T., Saunders, K. W., & Korff, M. V. (2005) · Pain · doi:10.1016/j.pain.2005.08.011 · Cited by 287
Self-citation
The kappa opioid nalbuphine produces gender- and dose-dependent analgesia and antianalgesia in patients with postoperative pain
Gear, R. W., Miaskowski, C. A., Gordon, N. C., Paul, S. M., Heller, P. H., & Levine, J. D. (1999) · Pain · doi:10.1016/s0304-3959(99)00119-0 · Cited by 272
Size and burden of depressive disorders in Europe
Paykel, E. S., Brugha, T. S., & Fryers, T. (2005) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2005.04.008 · Cited by 272
Multi-method assessment of experimental and clinical pain in patients with fibromyalgia
Lautenbacher, S., Rollman, G. B., & McCain, G. A. (1994) · Pain · doi:10.1016/0304-3959(94)90046-9 · Cited by 270
Self-citation
Sex differences in the antagonism of swim stress-induced analgesia: effects of gonadectomy and estrogen replacement
Mogil, J. S., Sternberg, W. F., Kest, B., Marek, P., & Liebeskind, J. C. (1993) · Pain · doi:10.1016/0304-3959(93)90050-y · Cited by 260
Self-citation
The effects of experimenter characteristics on pain reports in women and men
Kállai, I., Barke, A., & Voss, U. (2004) · Pain · doi:10.1016/j.pain.2004.08.008 · Cited by 259
Characteristics of Temporal Summation of Second Pain Sensations Elicited by Brief Contact of Glabrous Skin by a Preheated Thermode
Vierck, C. J., Cannon, R. L., Fry, G., Maixner, W. D., & Whitsel, B. L. (1997) · Journal of Neurophysiology · doi:10.1152/jn.1997.78.2.992 · Cited by 257
Untitled work
(1967) · PubMed · Cited by 257
Pain threshold variations in somatic wall tissues as a function of menstrual cycle, segmental site and tissue depth in non-dysmenorrheic women, dysmenorrheic women and men
Giamberardino, M. A., Berkley, K. J., Iezzi, S., de Bigontina, P., & Vecchiet, L. (1997) · Pain · doi:10.1016/s0304-3959(97)03362-9 · Cited by 255
Self-citation
Sex Chromosome Complement and Gonadal Sex Influence Aggressive and Parental Behaviors in Mice
Gatewood, J. D., Wills, A., Shetty, S. R. J., Xu, J., Arnold, A. P., Burgoyne, P. S., & Rissman, E. F. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3743-05.2006 · Cited by 253
Pain in infancy: Neonatal reaction to a heel lance
Owens, M. E., & Todt, E. H. (1984) · Pain · doi:10.1016/0304-3959(84)90813-3 · Cited by 251
Brain Estradiol Content in Newborn Rats: Sex Differences, Regional Heterogeneity, and Possible de Novo Synthesis by the Female Telencephalon
Amateau, S. K., Alt, J., Stamps, C. L., & McCarthy, M. M. (2004) · Endocrinology · doi:10.1210/en.2003-1363 · Cited by 246
Sex-Related Differences in Human Pain and Rat Afferent Discharge Evoked by Injection of Glutamate Into the Masseter Muscle
Cairns, B. E., Hu, J. W., Arendt‐Nielsen, L., Sessle, B. J., & Svensson, P. J. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.86.2.782 · Cited by 244
Self-citation
Does Gender Affect Appraisal of Pain and Pain Coping Strategies?
Unruh, A. M., Ritchie, J., & Merskey, H. (1999) · Clinical Journal of Pain · doi:10.1097/00002508-199903000-00006 · Cited by 240
Sex hormones, central nervous system and pain.
Aloisi, A., & Bonifazi, M. (2006) · Hormones and Behavior · doi:10.1016/j.yhbeh.2005.12.002 · Cited by 239
Validity of self-report measures of girls' pubertal status.
Jeanne Brooks-gunn, B., Warren, M. P., Rosso, J., & Gargiulo, J. (1987) · PubMed · Cited by 238
Gender difference in analgesic response to the kappa-opioid pentazocine
Gear, R. W., Gordon, N. C., Heller, P. H., Paul, S. M., Miaskowski, C. A., & Levine, J. D. (1996) · Neuroscience Letters · doi:10.1016/0304-3940(96)12402-2 · Cited by 232
Individual differences in pain responses
Fillingim, R. B. (2005) · Current Rheumatology Reports · doi:10.1007/s11926-005-0018-7 · Cited by 231
Self-citation
An Asia-Pacific, double blind, placebo controlled, randomised study to evaluate the efficacy, safety, and tolerability of tegaserod in patients with irritable bowel syndrome
Kellow, J. E., Lee, O. Y., Chang, F. Y., Thongsawat, S., Mazlam, M. Z., Yuen, H., Gwee, K., Bak, Y., Jones, J., & Wagner, A. (2003) · Gut · doi:10.1136/gut.52.5.671 · Cited by 230
Estrogen-Induced Alteration of μ-Opioid Receptor Immunoreactivity in the Medial Preoptic Nucleus and Medial Amygdala
Eckersell, C. B., Popper, P., & Micevych, P. E. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-10-03967.1998 · Cited by 221
Psychosocial contributions to sex-correlated differences in pain
Myers, C. D., Riley, J. L., & Robinson, M. E. (2003) · The Clinical Journal of Pain · doi:10.1097/00002508-200307000-00005 · Cited by 211
Does experimental pain response vary across the menstrual cycle? A methodological review
Sherman, J. J., & LeResche, L. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00920.2005 · Cited by 206
Self-citation
Gonadal steroid hormone modulation of nociception, morphine antinociception and reproductive indices in male and female rats
Stoffel, E. C., Ulibarri, C., & Craft, R. M. (2003) · Pain · doi:10.1016/s0304-3959(02)00457-8 · Cited by 201
Self-citation
Relative antidepressant efficacy of venlafaxine and SSRIs: sex-age interactions
Thase, M. E., Entsuah, R., Cantillon, M., & Kornstein, S. G. (2005) · Journal of Women s Health · doi:10.1089/jwh.2005.14.609 · Cited by 201
The effect of experimenter gender on autonomic and subjective responses to pain stimuli
Aslaksen, P. M., Myrbakk, I. N., Høifødt, R. S., & Flaten, M. A. (2006) · Pain · doi:10.1016/j.pain.2006.10.011 · Cited by 194
Influences of gender role and anxiety on sex differences in temporal summation of pain
Robinson, M. E., Wise, E. A., Gagnon, C., Fillingim, R. B., & Price, D. D. (2004) · The Journal of Pain · doi:10.1016/j.jpain.2003.11.004 · Cited by 193
Self-citation
Organization of circadian functions: interaction with the body
Buijs, R. M., Scheer, F. A. J. L., Kreier, F., Yi, C., Bos, N. P. A., Goncharuk, V. D., & Kalsbeek, A. (2006) · Progress in brain research · doi:10.1016/s0079-6123(06)53020-1 · Cited by 189
Gonadal Hormones and Sex Differences in Pain Reactivity
Aloisi, A. M. (2003) · Clinical Journal of Pain · doi:10.1097/00002508-200305000-00004 · Cited by 189
Pain rating by patients and physicians: evidence of systematic pain miscalibration
Marquié, L., Raufaste, É., Lauque, D., Mariné, C., Ecoiffier, M., & Sorum, P. C. (2003) · Pain · doi:10.1016/s0304-3959(02)00402-5 · Cited by 188
Analysis of gender effects on pain perception and symptom presentation in temporomandibular pain
Bush, F. M., Harkins, S. W., Harrington, W. G., & Price, D. D. (1993) · Pain · doi:10.1016/0304-3959(93)90058-w · Cited by 188
Momentary relationship between cortisol secretion and symptoms in patients with fibromyalgia
McLean, S. A., Williams, D. A., Harris, R. E., Kop, W. J., Groner, K. H., Ambrose, K., Lyden, A. K., Gracely, R. H., Crofford, L. J., Geisser, M. E., et al. (2005) · Arthritis & Rheumatism · doi:10.1002/art.21372 · Cited by 187
Sex-related Differences in the Influence of Morphine on Ventilatory Control in Humans
Dahan, A., Sarton, E. Y., Teppema, L. J., & Olievier, C. N. (1998) · Anesthesiology · doi:10.1097/00000542-199804000-00009 · Cited by 181
Sex differences in adolescent chronic pain and pain‐related coping
Keogh, E., & Eccleston, C. (2006) · Pain · doi:10.1016/j.pain.2006.03.004 · Cited by 180
The Influence of Resting Blood Pressure and Gender on Pain Responses
Fillingim, R. B., & Maixner, W. D. (1996) · Psychosomatic Medicine · doi:10.1097/00006842-199607000-00005 · Cited by 180
Self-citation
The Analgesic Effects of Supraspinal μ and δ Opioid Receptor Agonists Are Potentiated during Persistent Inflammation
Hurley, R. W., & Hammond, D. L. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-03-01249.2000 · Cited by 175
Sex differences in pain perception and anxiety. A psychophysical study with topical capsaicin
Frot, M., Feine, J. S., & Bushnell, C. M. (2004) · Pain · doi:10.1016/j.pain.2003.11.017 · Cited by 171
Gender differences in temporal summation of mechanically evoked pain
Sarlani, E., & Greenspan, J. D. (2002) · Pain · doi:10.1016/s0304-3959(02)00015-5 · Cited by 171
Self-citation
Altering gender role expectations: effects on pain tolerance, pain threshold, and pain ratings
Robinson, M. E., Gagnon, C. M., Riley, J. L., & Price, D. D. (2003) · Journal of Pain · doi:10.1016/s1526-5900(03)00559-5 · Cited by 169
Aging-Related Changes in Ovarian Hormones, Their Receptors, and Neuroendocrine Function
Chakraborty, T. R., & Gore, A. C. (2004) · Experimental Biology and Medicine · doi:10.1177/153537020422901001 · Cited by 168
Are XX and XY brain cells intrinsically different?
Arnold, A. P., & Burgoyne, P. S. (2003) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2003.11.001 · Cited by 166
Do men and women differ in their response to interdisciplinary chronic pain management?
Keogh, E., McCracken, L. M., & Eccleston, C. (2005) · Pain · doi:10.1016/j.pain.2004.12.009 · Cited by 164
Chronic pain and use of ambulatory health care.
Korff, M. V., Wagner, E. H., Dworkin, S. F., & Saunders, K. W. (1991) · Psychosomatic Medicine · doi:10.1097/00006842-199101000-00006 · Cited by 164
A Yin-Yang Effect between Sex Chromosome Complement and Sex Hormones on the Immune Response
Palaszynski, K. M., Smith, D. L., Kamrava, S., Burgoyne, P. S., Arnold, A. P., & Voskuhl, R. R. (2005) · Endocrinology · doi:10.1210/en.2005-0284 · Cited by 163
Central nervous system plasticity and persistent pain.
Ren, K., & Dubner, R. A. (1999) · PubMed · Cited by 163
A randomized controlled component analysis of a behavioral medicine rehabilitation program for chronic spinal pain: are the effects dependent on gender?
Jensen, I. B., Bergström, G., Ljungquist, T., Bodin, L., & Nygren, Å. (2001) · Pain · doi:10.1016/s0304-3959(00)00420-6 · Cited by 162
Dose-response and time-response relationships between progesterone and the display of patterns of receptive and proceptive behavior in the female rat
Fadem, B. H., Barfield, R. J., & Whalen, R. E. (1979) · Hormones and Behavior · doi:10.1016/0018-506x(79)90033-3 · Cited by 160
Differences in pain expression between male and female newborn infants
Guinsburg, R., Peres, C. D. A., de Almeida, M. F. B., Balda, R. D. C. X., Berenguel, R. C., Tonelotto, J., & Kopelman, B. I. (2000) · Pain · doi:10.1016/s0304-3959(99)00258-4 · Cited by 156
VARIATIONS IN REGULATION OF ENERGY EXCHANGE ASSOCIATED WITH ESTRUS, DIESTRUS AND PSEUDOPREGNANCY IN RATS1
Brobeck, J. R., Wheatland, M., & Strominger, J. L. (1947) · Endocrinology · doi:10.1210/endo-40-2-65 · Cited by 156
Spinal and Supraspinal Contributions to Central Sensitization in Peripheral Neuropathy
Suzuki, R., & Dickenson, A. H. (2005) · Neurosignals · doi:10.1159/000087656 · Cited by 153
Immune-to-brain communication dynamically modulates pain: physiological and pathological consequences
Wieseler-Frank, J., Maier, S. F., & Watkins, L. R. (2005) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2004.08.004 · Cited by 151
Gender differences in depression and response to antidepressant treatment
Sloan, D. M. E., & Kornstein, S. G. (2003) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(03)00044-3 · Cited by 150
Role of Steroids in Sex Differences in Morphine-Induced Analgesia: Activational and Organizational Effects
Cicero, T. J., Nock, B., O’Connor, L., & Meyer, E. R. (2002) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.300.2.695 · Cited by 150
The EflFects of Gonadal Steroids on Plasma Gonadotropins and Prolactin in the Rat1
Kalra, P. S., Fawcett, C. P., Krulich, L., et al. (1973) · Endocrinology · doi:10.1210/endo-92-4-1256 · Cited by 148
Why Look in the Brain for Answers to Temporomandibular Disorder Pain?
Sarlani, E., & Greenspan, J. D. (2005) · Cells Tissues Organs · doi:10.1159/000086200 · Cited by 145
Self-citation
The Usefulness of a Urinary LH Kit for Ovulation Prediction During Menstrual Cycles of Normal Women
Miller, P. D., & Soules, M. R. (1996) · Obstetrics and Gynecology · doi:10.1016/0029-7844(95)00352-5 · Cited by 143
The Luteinizing Hormone Surge Is Preceded by an Estrogen-Induced Increase of Hypothalamic Progesterone in Ovariectomized and Adrenalectomized Rats
Micevych, P. E., Sinchak, K., Mills, R. H., Tao, L., LaPolt, P. S., & Lu, J. K. H. (2003) · Neuroendocrinology · doi:10.1159/000071703 · Cited by 141
Maintenance of windup of second pain requires less frequent stimulation in fibromyalgia patients compared to normal controls
Staud, R. M., Price, D. D., Robinson, M. E., Mauderli, A. P., & Vierck, C. J. (2004) · Pain · doi:10.1016/j.pain.2004.05.009 · Cited by 139
17-β-Estradiol and progesterone modulate an intrinsic opioid analgesic system
Dawson-Basoa, M., & Gintzler, A. R. (1993) · Brain Research · doi:10.1016/0006-8993(93)91716-6 · Cited by 138
Evidence for up-regulated central nociceptive processing in patients with masticatory myofascial pain.
Sarlani, E., Grace, E. G., Reynolds, M. A., & Greenspan, J. D. (2004) · PubMed · Cited by 136
Self-citation
Estrogen Modulation of G‐Protein‐Coupled Receptor Activation of Potassium Channels in the Central Nervous System
Kelly, M. J., Qiu, J., & Rønnekleiv, O. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1286.001 · Cited by 135
Distribution of gonadal steroid receptor–containing neurons in the preoptic–periaqueductal gray–brainstem pathway: A potential circuit for the initiation of male sexual behavior
Murphy, A. Z., & Hoffman, G. E. (2001) · The Journal of Comparative Neurology · doi:10.1002/cne.1309 · Cited by 135
Self-citation
Is self-reported childhood abuse history associated with pain perception among healthy young women and men?
Fillingim, R. B., & Edwards, R. R. (2005) · The Clinical Journal of Pain · doi:10.1097/01.ajp.0000149801.46864.39 · Cited by 133
Self-citation
Pain Perception and Expression: The Influence of Gender, Personal Self-Efficacy, and Lifespan Socialization
Miller, C., & Newton, S. E. (2006) · Pain Management Nursing · doi:10.1016/j.pmn.2006.09.004 · Cited by 133
Sex differences in temporal summation of pain and aftersensations following repetitive noxious mechanical stimulation
Sarlani, E., Grace, E. G., Reynolds, M. A., & Greenspan, J. D. (2004) · Pain · doi:10.1016/j.pain.2004.01.019 · Cited by 132
Self-citation
Gender Differences in the Membrane Transport of Endogenous and Exogenous Compounds
Morris, M. E., Lee, H., & Predko, L. M. (2003) · Pharmacological Reviews · doi:10.1124/pr.55.2.1 · Cited by 130
Prolonged ovarian sex steroid treatment of male rats produces antinociception: identification of sex-based divergent analgesic mechanisms
Liu, N., & Gintzler, A. R. (2000) · Pain · doi:10.1016/s0304-3959(99)00278-x · Cited by 127
A human experimental capsaicin model for trigeminal sensitization. Gender-specific differences
Gazerani, P., Andersen, O. K., & Arendt‐Nielsen, L. (2005) · Pain · doi:10.1016/j.pain.2005.08.009 · Cited by 124
Self-citation
The estrous cycle and estrogen modulate stress-induced analgesia.
Ryan, S. M., & Maier, S. F. (1988) · Behavioral Neuroscience · doi:10.1037//0735-7044.102.3.371 · Cited by 124
A Comparison of Modality-Specific Somatosensory Changes During Menstruation in Dysmenorrheic and Nondysmenorrheic Women
Bajaj, P., Bajaj, P., Madsen, H., & Arendt‐Nielsen, L. (2002) · Clinical Journal of Pain · doi:10.1097/00002508-200205000-00007 · Cited by 123
Self-citation
Gender moderates the association between depression and disability in chronic pain patients
Keogh, E., McCracken, L. M., & Eccleston, C. (2005) · European Journal of Pain · doi:10.1016/j.ejpain.2005.05.007 · Cited by 123
Sex differences in the anatomical and functional organization of the periaqueductal gray‐rostral ventromedial medullary pathway in the rat: A potential circuit mediating the sexually dimorphic actions of morphine
Averitt, D. L., & Murphy, A. Z. (2006) · The Journal of Comparative Neurology · doi:10.1002/cne.20962 · Cited by 123
Self-citation
Families at high and low risk for depression: A three-generation startle study
Grillon, C., Warner, V., Hille, J., Merikangas, K. R., Bruder, G. E., Tenke, C. E., Nomura, Y., Leite, P., & Weissman, M. M. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.01.045 · Cited by 121
Circadian Rhythms of Women with Fibromyalgia
Klerman, E. B., Goldenberg, D. L., Brown, E. N., Maliszewski, A. M., & Adler, G. K. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.3.7293 · Cited by 120
Recommendations from a multi-study evaluation of proposed criteria for Staging Reproductive Aging
Harlow, S. D., Crawford, S. L., Dennerstein, L., Burger, H., Mitchell, E. S., Sowers, M., & for the ReSTAGE Collaboration (2007) · Climacteric · doi:10.1080/13697130701258838 · Cited by 118
Effect of sex on perception of rectosigmoid stimuli in irritable bowel syndrome
Chang, L., Mayer, E. A., Labus, J. S., Schmulson, M. J., Lee, O. Y., Olivas, T. I., Stains, J., & Naliboff, B. D. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00729.2005 · Cited by 116
Self-citation
Rapid Regulation of Pain by Estrogens Synthesized in Spinal Dorsal Horn Neurons
Evrard, H., & Balthazart, J. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.1638-04.2004 · Cited by 115
Patterns of Salivary Estradiol and Progesterone across the Menstrual Cycle
Gandara, B., LeResche, L., & Mancl, L. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1384.022 · Cited by 114
Self-citation
Female rats are more vulnerable to the long-term consequences of neonatal inflammatory injury
LaPrairie, J. L., & Murphy, A. Z. (2007) · Pain · doi:10.1016/j.pain.2007.08.010 · Cited by 114
Self-citation
The estrous cycle and estrogen modulate stress-induced analgesia.
Ryan, S. M., & Maier, S. F. (1988) · Behavioral Neuroscience · doi:10.1037/0735-7044.102.3.371 · Cited by 109
Nociceptive Sensitivity and Opioid Antinociception and Antihyperalgesia in Freund’s Adjuvant-Induced Arthritic Male and Female Rats
Cook, C. D., & Nickerson, M. D. (2005) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.104.077792 · Cited by 107
A double‐blind, placebo‐controlled, randomized study to evaluate the efficacy, safety and tolerability of tegaserod in patients with irritable bowel syndrome
Nyhlin, H., Bang, C. J., Elsborg, L., Silvennoinen, J. I. K., Holme, I., Rüegg, P. C., Jones, J. J., & Wagner, A. (2004) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520310006748 · Cited by 106
Inflammatory Pain Upregulates Spinal Inhibition via Endogenous Neurosteroid Production
Poisbeau, P., Patte‐Mensah, C., Keller, A. F., Barrot, M., Breton, J., Luis‐Delgado, O. E., Freund‐Mercier, M. J., Mensah‐Nyagan, A. G., & Schlichter, R. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.3841-05.2005 · Cited by 105
Persistent pain model reveals sex difference in morphine potency
Wang, X., Traub, R. J., & Murphy, A. Z. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00022.2006 · Cited by 105
Self-citation
ICI 182,780: a pure antiestrogen that affects behaviors and energy balance in rats without acting in the brain
Wade, G. N., Blaustein, J. D., Gray, J., & Meredith, J. M. (1993) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1993.265.6.r1392 · Cited by 105
Sexual and Physical Abuse in Women With Fibromyalgia Syndrome
Ciccone, D. S., Elliott, D. K., Chandler, H. K., Nayak, S., & Raphael, K. G. (2005) · Clinical Journal of Pain · doi:10.1097/01.ajp.0000149796.08746.ea · Cited by 104
Vaginal lavage attenuates cocaine-stimulated activity and establishes place preference in rats
Walker, Q. D., Nelson, C. J., Smith, D., & Kuhn, C. M. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(02)00883-3 · Cited by 104
Sex and the Liver – A Journey Through Five Decades
Mode, A., & Gustafsson, J.-Α. (2006) · Drug Metabolism Reviews · doi:10.1080/03602530600570057 · Cited by 101
EXPERIMENTAL PAIN THRESHOLDS INFLUENCED BY SEX OF EXPERIMENTER
Gijsbers, K., & Nicholson, F. (2005) · Perceptual and Motor Skills · doi:10.2466/pms.101.3.803-807 · Cited by 99
Does past pain influence current pain: biological and psychosocial models of sex differences
Rollman, G. B., Abdel‐Shaheed, J., Gillespie, J. M., & Jones, K. S. (2004) · European Journal of Pain · doi:10.1016/j.ejpain.2004.03.002 · Cited by 99
Drugs and sex differences: a review of drugs relating to anaesthesia
Ciccone, G. K., & Holdcroft, A. (1999) · British Journal of Anaesthesia · doi:10.1093/bja/82.2.255 · Cited by 98
Self-citation
Sex differences in endogenous pain modulation by distracting and painful conditioning stimulation
Quiton, R. L., & Greenspan, J. D. (2007) · Pain · doi:10.1016/j.pain.2007.09.001 · Cited by 98
Self-citation
Estrogen Induces de novo Progesterone Synthesis in Astrocytes
Sinchak, K., Mills, R. H., Tao, L., LaPolt, P. S., Lu, J. K. H., & Micevych, P. E. (2003) · Developmental Neuroscience · doi:10.1159/000073511 · Cited by 97
Estrogen-dependent abdominal hyperalgesia induced by ovariectomy in adult mice: A model of functional abdominal pain
Sanoja, R., & Cerveró, F. (2005) · Pain · doi:10.1016/j.pain.2005.08.021 · Cited by 95
Social isolation and the inflammatory response: sex differences in the enduring effects of a prior stressor
Hermes, G. L., Rosenthal, L., Montag, A., & McClintock, M. K. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00368.2005 · Cited by 94
Female rats are more susceptible to the development of neuropathic pain using the partial sciatic nerve ligation (PSNL) model
Coyle, D. E., Sehlhorst, C. S., & Mascari, C. (1995) · Neuroscience Letters · doi:10.1016/0304-3940(95)11304-f · Cited by 92
Dispositional anxiety and the experience of pain: gender‐specific effects
Jones, A., Zachariae, R. H., & Arendt‐Nielsen, L. (2003) · European Journal of Pain · doi:10.1016/s1090-3801(02)00139-8 · Cited by 91
Self-citation
Sex differences in GABA/benzodiazepine receptor changes and corticosterone release after acute stress in rats
Wilson, M. A., & Biscardi, R. (1994) · Experimental Brain Research · doi:10.1007/bf00228750 · Cited by 90
The effects of gonadectomy on the sex differences in dietary self-selection patterns and carcass compositions of rats.
Leshner, A. I., & Collier, G. H. (1973) · Physiology and Behavior · doi:10.1016/0031-9384(73)90253-9 · Cited by 89
Evidence of gender differences in esophageal pain threshold.
Nguyen, P. T., Lee, S. D., & Do, C. (1995) · PubMed · Cited by 89
Effects of Dehydroepiandrosterone and Flutamide on Hippocampal CA1 Spine Synapse Density in Male and Female Rats: Implications for the Role of Androgens in Maintenance of Hippocampal Structure
MacLusky, N. J., Hajszán, T., & Léránth, C. (2004) · Endocrinology · doi:10.1210/en.2004-0477 · Cited by 89
Reversal of sex differences in morphine analgesia elicited from the ventrolateral periaqueductal gray in rats by neonatal hormone manipulations
Krzanowska, E. K., Ogawa, S., Pfaff, D. W., & Bodnar, R. J. (2002) · Brain Research · doi:10.1016/s0006-8993(01)03350-9 · Cited by 88
The role of female gonadal hormones in behavioral sex differences in persistent and chronic pain: Clinical versus preclinical studies
Kuba, T., & Quiñones-Jenab, V. (2005) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2005.05.009 · Cited by 88
Musculoskeletal orofacial pain and other signs and symptoms of temporomandibular disorders during pregnancy: a prospective study.
LeResche, L., Sherman, J. J., Huggins, K. H., Saunders, K. W., Mancl, L. A., Lentz, G. M., & Dworkin, S. F. (2005) · PubMed · Cited by 87
Self-citation
Sex and gender differences in pain and inflammation: a rapidly maturing field
Berkley, K. J., Zalcman, S. S., & Simon, V. R. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00287.2006 · Cited by 86
Self-citation
Morphine preferentially activates the periaqueductal gray–rostral ventromedial medullary pathway in the male rat: A potential mechanism for sex differences in antinociception
Averitt, D. L., Morgan, M. M., & Murphy, A. Z. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.03.053 · Cited by 86
Self-citation
The probability of recovery and return to work from work disability as a function of time
Crook, J., & Moldofsky, H. (1994) · Quality of Life Research · doi:10.1007/bf00433383 · Cited by 83
Visceral pain: gender differences in response to experimental and clinical pain
Arendt‐Nielsen, L., Bajaj, P., & Drewes, A. M. (2004) · European Journal of Pain · doi:10.1016/j.ejpain.2004.03.001 · Cited by 83
Self-citation
Increased muscle pain sensitivity in patients with tension-type headache
Schmidt-Hansen, P. T., Svensson, P. J., Bendtsen, L., Graven‐Nielsen, T., & Bach, F. W. (2006) · Pain · doi:10.1016/j.pain.2006.09.037 · Cited by 82
Daily and hourly estrous running in intact, spayed, and estrone implanted rats
Gerall, A. A., Napoli, A. M., & Cooper, U. C. (1973) · Physiology & Behavior · doi:10.1016/0031-9384(73)90302-8 · Cited by 82
Rectal visceral sensitivity in healthy volunteers: influences of gender, age and methods
Sloots, Felt-Bersma, R. J. F., Cuesta, & Meuwissen, S. G. M. (2000) · Neurogastroenterology & Motility · doi:10.1046/j.1365-2982.2000.00210.x · Cited by 80
Steroid Hormone Analysis in Human Saliva
Quissell, D. O. (1993) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1993.tb18348.x · Cited by 79
Estrogen receptor expression in lumbosacral dorsal root ganglion cells innervating the female rat urinary bladder
Bennett, H. L., Gustafsson, J., & Keast, J. R. (2003) · Autonomic Neuroscience · doi:10.1016/s1566-0702(03)00044-4 · Cited by 78
Antiestrogenic Action of Raloxifene and Tamoxifen: Today and Tomorrow
Jordan, V. C. (1998) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/90.13.967 · Cited by 78
Pain and uterine contractions during breast feeding in the immediate post-partum period increase with parity
Holdcroft, A., Snidvongs, S., Cason, A. M., et al. (2003) · Pain · doi:10.1016/s0304-3959(03)00116-7 · Cited by 75
Self-citation
Effects of subcutaneous administration of glutamate on pain, sensitization and vasomotor responses in healthy men and women
Gazerani, P., Wang, K., Cairns, B. E., Svensson, P. J., & Arendt‐Nielsen, L. (2006) · Pain · doi:10.1016/j.pain.2006.06.015 · Cited by 74
Self-citation
Androgens influence sexual differentiation of embryonic mouse hypothalamic aromatase neurons in vitro
Beyer, C., Green, S. J., & Hutchison, J. B. (1994) · Endocrinology · doi:10.1210/endo.135.3.8070366 · Cited by 74
Gender-related effects of chronic non-malignant pain and opioid therapy on plasma levels of macrophage migration inhibitory factor (MIF)
Aloisi, A. M., Pari, G., Ceccarelli, I., Vecchi, I., Ietta, F., Lodi, L., & Paulesu, L. R. (2005) · Pain · doi:10.1016/j.pain.2005.02.019 · Cited by 73
Psychosocial mediators of sex differences in pain responsivity
Sanford, S. D., Kersh, B. C., Thorn, B. E., Rich, M. A., & Ward, L. C. (2002) · Journal of Pain · doi:10.1054/jpai.2002.xb30066 · Cited by 72
Gender and the behavioral manifestations of neuropathic pain
Tall, J. M., Stuesse, S. L., Cruce, W. L. R., & Crisp, T. (2001) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(00)00461-5 · Cited by 72
Sex hormonal effects on the severity of streptococcal cell wall‐induced polyarthritis in the rat
Allen, J. B., Blatter, D. D., Calandra, G., & Wilder, R. L. (1983) · Arthritis & Rheumatism · doi:10.1002/art.1780260418 · Cited by 68
Gonadectomy Affects Hormonal and Behavioral Responses to Repetitive Nociceptive Stimulation in Male Rats
ALOISI, A. M., CECCARELLI, I., & FIORENZANI, P. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1286.022 · Cited by 66
Sex Differences in Clinical Pain: A Multisample Study
Robinson, M. E., Wise, E. A., Riley, J. L., & Atchison, J. W. (1998) · Journal of Clinical Psychology in Medical Settings · doi:10.1023/a:1026282210848 · Cited by 65
Estrogen synthesis in the spinal dorsal horn: a new central mechanism for the hormonal regulation of pain
Evrard, H. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00930.2005 · Cited by 64
Evidence for Sex Differences in the Relationships of Pain, Mood, and Disability
Hirsh, A. T., Waxenberg, L. B., Atchison, J. W., Gremillion, H. A., & Robinson, M. E. (2006) · Journal of Pain · doi:10.1016/j.jpain.2006.02.006 · Cited by 63
Alterations in Brain Opiate Receptor Mechanisms on Proestrous Afternoon
Berglund, A., & Simpkins, J. W. (2008) · Neuroendocrinology · doi:10.1159/000125040 · Cited by 61
Effects of estrogen on plasma and pituitary gonadotropins and prolactin, and on hypothalamic releasing and inhibiting factors
Ajika, K., Krulich, L., Fawcett, C. P., & McCann, S. M. (2008) · Neuroendocrinology · doi:10.1159/000122062 · Cited by 61
Temporal summation of pain characterizes women but not men with temporomandibular disorders.
Sarlani, E., Garrett, P. H., Grace, E. G., & Greenspan, J. D. (2007) · PubMed · Cited by 60
Self-citation
Observations on the presentation, diagnosis, and treatment of interstitial cystitis in men
Forrest, J. B., & Vo, Q. (2001) · Urology · doi:10.1016/s0090-4295(01)01121-9 · Cited by 60
Number of social roles, health, and well-being in three generations of australian women
Lee, C., & Powers, J. R. (2002) · International Journal of Behavioral Medicine · doi:10.1207/s15327558ijbm0903_03 · Cited by 58
Sex differences in pain perception and cardiovascular responses in persons with parental history for hypertension
Al’Absi, M., Buchanan, T. W., Marrero, A., & Lovallo, W. R. (1999) · Pain · doi:10.1016/s0304-3959(99)00122-0 · Cited by 57
Responsiveness to laboratory pain in women as a function of age and childbirth pain experience
Hapidou, E. G., & deCatanzaro, D. (1992) · Pain · doi:10.1016/0304-3959(92)90056-h · Cited by 53
Dose‐ and time‐dependent estradiol modulation of morphine antinociception in adult female rats
Craft, R. M., Ulibarri, C., Leitl, M. D., & Sumner, J. E. (2007) · European Journal of Pain · doi:10.1016/j.ejpain.2007.07.014 · Cited by 52
Self-citation
The reporting of pain, somatic complaints, and anxiety in a group of patients with TMD before and 2 years after treatment: sex differences.
Krogstad, B. S., Jokstad, A., DAHL, B. L., & Vassend, O. M. (1996) · PubMed · Cited by 51
Sexually Dimorphic Recruitment of Spinal Opioid Analgesic Pathways by the Spinal Application of Morphine
Liu, N., von Gizycki, H., & Gintzler, A. R. (2007) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.107.123620 · Cited by 49
Effects of estrogen deprivation on brain estrogen and progestin receptor levels and the activation of female sexual behavior
Clark, C. R., MacLusky, N. J., Parsons, B., et al. (1981) · Hormones and Behavior · doi:10.1016/0018-506x(81)90018-0 · Cited by 49
Are Gender, Marital Status or Parenthood Risk Factors for Outcome of Treatment for Chronic Disabling Spinal Disorders?
Gatchel, R. J., Mayer, T. G., Kidner, C. L., & McGeary, D. D. (2005) · Journal of Occupational Rehabilitation · doi:10.1007/s10926-005-1218-8 · Cited by 47
Reliability and validity of retrospective self-reports of the age of pubertal onset using twin, sibling, and college student data.
Gilger, J. W., Geary, D., & Eisele, L. M. (1991) · PubMed · Cited by 46
Differential Sensitivity of Estrogen Target Tissues: The Role of the Receptor*
Kelner, K. L., KIRCHICK, H. J., & Peck, E. J. (1982) · Endocrinology · doi:10.1210/endo-111-6-1986 · Cited by 41
Infant Gender Differences Regarding Acute Established Pain
Fuller, B. F. (2002) · Clinical Nursing Research · doi:10.1177/105477380201100207 · Cited by 38
A Modulatory Role for Luteinizing Hormone-Releasing Hormone in Nociceptive Responses of Female Rats
Ratka, A., & Simpkins, J. W. (1990) · Endocrinology · doi:10.1210/endo-127-2-667 · Cited by 36
Effects of Physical and Sexual Abuse in Facial Pain: Direct or Mediated?
Riley, J. L., Robinson, M. E., Kvaal, S. A., & Gremillion, H. A. (1998) · CRANIO® · doi:10.1080/08869634.1998.11746066 · Cited by 36
Activation of gonadotropin-releasing hormone receptors induces a long-term enhancement of excitatory postsynaptic currents mediated by ionotropic glutamate receptors in the rat hippocampus.
Yang, S.-N., Lu, F., Wu, J.-N., Liu, D. D., & Hsieh, W.-Y. (1999) · Neuroscience Letters · doi:10.1016/s0304-3940(98)00939-2 · Cited by 36

Research works printed but not linked: 2

Gilger, 1991, Reliability and validity of retrospective self-reports of the age of pubertal onset using twin., Adolescence, 26, 41
Yezierski, 2007, The next generation of pain scientists: the need for integrative and translational training in pain research., APS Bull, 17, 3

Sorted by citations

Sex, gender, and pain: a review of recent clinical and experimental findings
Fillingim, R. B., King, C. D., Ribeiro-Dasilva, M. C., Rahim-Williams, B., & Riley, J. L. (2009) · The Journal of Pain · doi:10.1016/j.jpain.2008.12.001 · Cited by 2,766
Self-citation
Sex and Gender Equity in Research: rationale for the SAGER guidelines and recommended use
Heidari, S., Babor, T. F., De Castro, P., Tort, S., & Curno, M. (2016) · Research Integrity and Peer Review · doi:10.1186/s41073-016-0007-6 · Cited by 2,184
Sex differences in pain: a brief review of clinical and experimental findings
Bartley, E. J., & Fillingim, R. B. (2013) · British Journal of Anaesthesia · doi:10.1093/bja/aet127 · Cited by 2,168
Self-citation
Sex bias in neuroscience and biomedical research
Beery, A. K., & Zucker, I. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.07.002 · Cited by 1,763
Chronic pain: a review of its epidemiology and associated factors in population-based studies
Mills, S. E. E., Nicolson, K. P., & Smith, B. H. (2019) · British Journal of Anaesthesia · doi:10.1016/j.bja.2019.03.023 · Cited by 1,728

See all 1,033

Authors: Greenspan, J. D., Craft, R. M., LeResche, L., Arendt-Nielsen, L., Berkley, K. J., Fillingim, R. B., Gold, M. S., Holdcroft, A., Lautenbacher, S., Mayer, E. A., Mogil, J. S., Murphy, A. Z., & Traub, R. J.
Affiliations: Florida State University (US)
Corresponding author: Greenspan, Joel D.
ORCID: Greenspan, Joel D.
Craft, Rebecca M.
Fillingim, Roger B.
Gold, Michael S.
Lautenbacher, Stefan
Mayer, Emeran A.
Mogil, Jeffrey S.
Murphy, Anne Z.
Traub, Richard J.
Venue: Pain
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2007-11
Volume: 132
Issue: Supplement 1
Pages: S26-S45
ISSN: 0304-3959 (ISSN-L)
DOI: 10.1016/j.pain.2007.10.014
PMC: PMC2823483
OpenAlex: W2085502426
Cited by: 1,033
References: 224
Citations by year: 2026: 22 · 2025: 46 · 2024: 44 · 2023: 53 · 2022: 59 · 2021: 56 · 2020: 64 · 2019: 54 · 2018: 62 · 2017: 58 · 2016: 66 · 2015: 53 · 2014: 59 · 2013: 72 · 2012: 57
FWCI: 48.05
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Pain (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
VBN Forskningsportal (Aalborg Universitet) (submittedVersion)
Funders: National Institute on Drug Abuse (R01DA016272)
National Institute of Diabetes and Digestive and Kidney Diseases (R01DK066641)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD039699)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Sex and Gender in Healthcare
Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
Keywords: sex differences, gender differences, analgesia, sexual differentiation, reproductive endocrinology, psychosocial pain
MeSH terms: Analgesics, Animals, Culture, Female, Gender Identity, Humans, Male, Menstrual Cycle, Pain, Psychology, Sex Characteristics, Gonadal Steroid Hormones, Models, Animal, Pain Management

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Studying sex and gender differences in pain and analgesia: A consensus report

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks