The DOI matches its Crossref record; 314 of the 314 references it cites were found in a registry or an index.
Oxidative stress in Alzheimer's disease
Open accessAbstract
Oxidative damage is a major feature in the pathophysiology of Alzheimer's disease (AD). In this review, we discuss free radical-mediated damage to the biochemical components involved in the pathology and clinical symptoms of AD. We explain how amyloid beta-protein (Abeta), microtubule-associated protein tau, presenilins, apolipoprotein E, mitochondria and proteases play a role in increasing oxidative stress in AD. Abeta not only can induce oxidative stress, but its generation is also increased as a result of oxidative stress. Finally, a hypothetical model linking oxidative stress with beta-amyloid and neurofibrillary tangle pathology in AD is proposed.
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Cites
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Neuroprotective Strategies for Neurological Disorders by Natural Products: An update
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In silico repurposing of antipsychotic drugs for Alzheimer’s disease
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“…tau is triggered by different signals, wherein the recent studies have indicated several overlapping manifestations between these two (Chauhan and Chauhan, 2006; Long and Holtzman, 2019), which also includes endoplasmic reticulum stress (ER stress) (Salminen et al., 2009; Guix et al., 2019).”
BackgroundKoh, S.-H., Kwon, H. S., Choi, S. H., Jeong, J. H., Na, H. R., Lee, C. N., Yang, Y., Lee, A. Y., Lee, J.-H., Park, K. W., et al. (2021) · Alzheimer's Research & Therapy · doi:10.1186/s13195-021-00803-w · Cited by 39
Ding, H., Reiss, A. B., Pinkhasov, A., & Kasselman, L. J. (2022) · Medicina · doi:10.3390/medicina58081025 · Cited by 32
Rao, K., Ramesh, B., Girish, T., Raghavendra, R., Naidu, K., & Prasada Rao, U. J. S. (2014) · Journal of Pharmacy And Bioallied Sciences · doi:10.4103/0975-7406.129172 · Cited by 26
Cholinesterase inhibitors and add-on nutritional supplements in Alzheimer's disease
Rijpma, A., Meulenbroek, O., & Olde Rikkert, M. G. M. (2014) · Ageing Research Reviews · doi:10.1016/j.arr.2014.06.002 · Cited by 26
Potential Role for Herpesviruses in Alzheimer’s Disease
Duggan, M. R., Torkzaban, B., Ahooyi, T. M., & Khalili, K. (2020) · Journal of Alzheimer's Disease · doi:10.3233/jad-200814 · Cited by 13
Metadata
- Authors
- Chauhan, V., & Chauhan, A.
- Venue
- Pathophysiology
- Publisher
- Elsevier BV
- Published
- 2006-08
- Volume
- 13
- Issue
- 3
- Pages
- 195-208
- ISSN
- 0928-4680 (ISSN-L)
- OpenAlex
- W2091711919
- Cited by
- 342
- References
- 314
- FWCI
- 8.04
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
