The DOI matches its Crossref record; 329 of the 329 references it cites were found in a registry or an index.
A systematic review of natural products for skin applications: Targeting inflammation, wound healing, and photo-aging
Open accessAbstract
BACKGROUND: Every day the skin is constantly exposed to several harmful factors that induce oxidative stress. When the cells are incapable to maintain the balance between antioxidant defenses and reactive oxygen species, the skin no longer can keep its integrity and homeostasis. Chronic inflammation, premature skin aging, tissue damage, and immunosuppression are possible consequences induced by sustained exposure to environmental and endogenous reactive oxygen species. Skin immune and non-immune cells together with the microbiome are essential to efficiently trigger skin immune responses to stress. For this reason, an ever-increasing demand for novel molecules capable of modulating immune functions in the skin has risen the level of their development, particularly in the field of natural product-derived molecules. PURPOSE: In this review, we explore different classes of molecules that showed evidence in modulate skin immune responses, as well as their target receptors and signaling pathways. Moreover, we describe the role of polyphenols, polysaccharides, fatty acids, peptides, and probiotics as possible treatments for skin conditions, including wound healing, infection, inflammation, allergies, and premature skin aging. METHODS: Literature was searched, analyzed, and collected using databases, including PubMed, Science Direct, and Google Scholar. The search terms used included "Skin", "wound healing", "natural products", "skin microbiome", "immunomodulation", "anti-inflammatory", "antioxidant", "infection", "UV radiation", "polyphenols", "polysaccharides", "fatty acids", "plant oils", "peptides", "antimicrobial peptides", "probiotics", "atopic dermatitis", "psoriasis", "auto-immunity", "dry skin", "aging", etc., and several combinations of these keywords. RESULTS: Natural products offer different solutions as possible treatments for several skin conditions. Significant antioxidant and anti-inflammatory activities were reported, followed by the ability to modulate immune functions in the skin. Several membrane-bound immune receptors in the skin recognize diverse types of natural-derived molecules, promoting different immune responses that can improve skin conditions. CONCLUSION: Despite the increasing progress in drug discovery, several limiting factors need future clarification. Understanding the safety, biological activities, and precise mechanisms of action is a priority as well as the characterization of the active compounds responsible for that. This review provides directions for future studies in the development of new molecules with important pharmaceutical and cosmeceutical value.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“The skin is another major target of stress-induced immune alterations; cytokine imbalance in this context—mostly IL6 and TNFa—can delay wound healing and accelerate cutaneous aging [47].”
From Chronic Stress and Autoimmunity: The Role of HPA Axis and Cortisol Dysregulation (2025) · cites this paper as [47]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“The majority of studies included in the review were preclinical or small‐scale clinical trials, warranting further research to establish the efficacy and safety of these interventions.”
From Cosmeceuticals in photoaging: A review. (2024) · cites this paper as [50]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Additionally, the heterogeneity of the included studies makes it challenging to draw definitive conclusions on the overall effectiveness of natural products for skin health.”
From Cosmeceuticals in photoaging: A review. (2024) · cites this paper as [50]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Based on the evidence presented in the review, it can be concluded that natural products show promise in addressing skin conditions and promoting skin health.”
From Cosmeceuticals in photoaging: A review. (2024) · cites this paper as [50]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
1 retracted
Huang, H.-N., Pan, C., Chan, Y.-L., Chen, J., & Wu, C. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02427-13 · Cited by 35
RetractedJemal, A., Siegel, R., Xu, J., & Ward, E. (2010) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.20073 · Cited by 12,596
Obesity is associated with macrophage accumulation in adipose tissue
Weisberg, S. P., McCann, D., Desai, M., Rosenbaum, M., Leibel, R. L., & Ferrante, A. W. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319246 · Cited by 10,041
Alginate: Properties and biomedical applications
Lee, K. Y., & Mooney, D. J. (2011) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2011.06.003 · Cited by 8,477
Natural products in drug discovery: advances and opportunities
Atanasov, A. G., Zotchev, S. B., Dirsch, V. M., Taskforce, T. I. N. P. S., Orhan, İ. E., Banach, M., Rollinger, J. M., Barreca, D., Weckwerth, W., Bauer, R., et al. (2021) · Nature Reviews Drug Discovery · doi:10.1038/s41573-020-00114-z · Cited by 5,891
Protective and pathogenic functions of macrophage subsets
Murray, P. J., & Wynn, T. A. (2011) · Nature Reviews Immunology · doi:10.1038/nri3073 · Cited by 5,269
Toll-like receptor control of the adaptive immune responses
Iwasaki, A., & Medzhitov, R. M. (2004) · Nature Immunology · doi:10.1038/ni1112 · Cited by 4,166
Grice, E. A., & Segre, J. A. (2011) · Nature Reviews Microbiology · doi:10.1038/nrmicro2537 · Cited by 3,143
Targeting oxidative stress in disease: Promise and limitations of antioxidant therapy
Forman, H. J., & Zhang, H. (2021) · Nature Reviews Drug Discovery · doi:10.1038/s41573-021-00233-1 · Cited by 2,900
Byrd, A. L., Belkaid, Y., & Segre, J. A. (2018) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2017.157 · Cited by 2,806
Chitin and Chitosan Preparation from Marine Sources. Structure, Properties and Applications
Younes, I., & Rinaudo, M. (2015) · Marine Drugs · doi:10.3390/md13031133 · Cited by 2,620
Evolution of the immune system in humans from infancy to old age
Simon, A. K., Hollander, G. A., & McMichael, A. (2015) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2014.3085 · Cited by 1,796
Dysbiosis and the immune system
Levy, M., Kolodziejczyk, A. A., Thaiss, C. A., & Elinav, E. (2017) · Nature Reviews Immunology · doi:10.1038/nri.2017.7 · Cited by 1,769
Okabe, Y., & Medzhitov, R. (2014) · Cell · doi:10.1016/j.cell.2014.04.016 · Cited by 884
Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cells
Merad, M., Ginhoux, F., & Collin, M. (2008) · Nature Reviews Immunology · doi:10.1038/nri2455 · Cited by 850
Hyaluronic acid—Based wound dressings: A review
Graça, M. F. P., Miguel, S. P., Cabral, . S. D., & Correia, I. J. (2020) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2020.116364 · Cited by 843
Development of a chitosan-based wound dressing with improved hemostatic and antimicrobial properties
Ong, S.-Y., Wu, J., Moochhala, S., Tan, M. H., & Jia, L. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.07.034 · Cited by 835
Commensal–dendritic-cell interaction specifies a unique protective skin immune signature
Naik, S., Bouladoux, N., Linehan, J. L., Han, S.-J., Harrison, O. J., Wilhelm, C., Conlan, S., Himmelfarb, S., Byrd, A. L., Deming, C., et al. (2015) · Nature · doi:10.1038/nature14052 · Cited by 820
Tamoutounour, S., Guilliams, M., Montanana Sanchis, F., Liu, H., Terhorst, D., Malosse, C., Pollet, E., Ardouin, L., Luche, H., Sanchez, C., et al. (2013) · Immunity · doi:10.1016/j.immuni.2013.10.004 · Cited by 783
Commensal bacteria regulate Toll-like receptor 3–dependent inflammation after skin injury
Lai, Y., Di Nardo, A., Nakatsuji, T., Leichtle, A., Yang, Y., Cogen, A. L., Wu, Z.-R., Hooper, L. V., Schmidt, R. R., von Aulock, S., et al. (2009) · Nature Medicine · doi:10.1038/nm.2062 · Cited by 781
The Dynamics of the Skin’s Immune System
Nguyen, A. V., & Soulika, A. M. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20081811 · Cited by 759
Pessemier, B. D., Grine, L., Debaere, M., Maes, A., Paetzold, B., & Callewaert, C. (2021) · Microorganisms · doi:10.3390/microorganisms9020353 · Cited by 689
Yousefi, S. R., Alshamsi, H. A., Amiri, O., et al. (2021) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2021.116405 · Cited by 665
Hyaluronic Acid: Molecular Mechanisms and Therapeutic Trajectory
Gupta, R. C., Lall, R., Srivastava, A., & Sinha, A. (2019) · Frontiers in Veterinary Science · doi:10.3389/fvets.2019.00192 · Cited by 662
The immunological anatomy of the skin
Kabashima, K., Honda, T., Ginhoux, F., & Egawa, G. (2019) · Nature Reviews Immunology · doi:10.1038/s41577-018-0084-5 · Cited by 650
Martins, A., Vieira, H., Gaspar, H., & Santos, S. (2014) · Marine Drugs · doi:10.3390/md12021066 · Cited by 600
Emerging interactions between skin stem cells and their niches
Hsu, Y., Li, L., & Fuchs, E. V. (2014) · Nature Medicine · doi:10.1038/nm.3643 · Cited by 590
Hammarström, S., Hámberg, M., Samuelsson, B. O., Duell, E. J., Stawiski, M. A., & Voorhees, J. J. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.12.5130 · Cited by 586
Dysbiosis and Staphylococcus aureus Colonization Drives Inflammation in Atopic Dermatitis
Kobayashi, T., Glatz, M., Horiuchi, K., Kawasaki, H., Akiyama, H., Kaplan, D. H., Kong, H. H., Amagai, M., & Nagao, K. (2015) · Immunity · doi:10.1016/j.immuni.2015.03.014 · Cited by 566
Staphylococcus δ-toxin induces allergic skin disease by activating mast cells
Nakamura, Y., Oscherwitz, J., Cease, K. B., Chan, S. M., Muñoz-Planillo, R., Hasegawa, M., Villaruz, A. E., Cheung, G. Y. C., McGavin, M. J., Travers, J. B., et al. (2013) · Nature · doi:10.1038/nature12655 · Cited by 558
Flavonols, Flavones, Flavanones, and Human Health: Epidemiological Evidence
Graf, B. A., Milbury, P. E., & Blumberg, J. B. (2005) · Journal of Medicinal Food · doi:10.1089/jmf.2005.8.281 · Cited by 556
The Immune Functions of Keratinocytes in Skin Wound Healing
Piipponen, M., Li, D., & Xu, N. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21228790 · Cited by 550
Karami, Z., & Akbari‐adergani, B. (2019) · Journal of Food Science and Technology · doi:10.1007/s13197-018-3549-4 · Cited by 548
Taylor, A. L., Dunstan, J. A., & Prescott, S. L. (2007) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2006.08.036 · Cited by 541
Medicinal importance of fungal β-(1→3), (1→6)-glucans
Chen, J., & Seviour, R. J. (2007) · Mycological Research · doi:10.1016/j.mycres.2007.02.011 · Cited by 539
Hyaluronic Acid in Inflammation and Tissue Regeneration.
Litwiniuk, M., Krejner, A., Speyrer, M. S., Gauto, A. R., & Grzela, T. (2016) · PubMed · Cited by 523
Curcumin-encapsulated nanoparticles as innovative antimicrobial and wound healing agent
Krausz, A. E., Adler, B., Cabral, V., Navati, M. S., Doerner, J., Charafeddine, R. A., Chandra, D., Liang, H., Gunther-Cummins, L., Clendaniel, A., et al. (2014) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2014.09.004 · Cited by 521
Adhesion of epidermal Langerhans cells to keratinocytes mediated by E-cadherin
Tang, A., Amagai, M., Granger, L. G., Stanley, J. R., & Uddy, M. C. (1993) · Nature · doi:10.1038/361082a0 · Cited by 502
Natural products to drugs: natural product derived compounds in clinical trials
Butler, M. S. (2005) · Natural Product Reports · doi:10.1039/b402985m · Cited by 496
Epidemiology of Skin Cancer: Update 2019
Leiter, U., Keim, U., & Garbe, C. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-46227-7_6 · Cited by 494
Mahdi, M. A., Yousefi, S. R., Jasim, L. S., et al. (2022) · International Journal of Hydrogen Energy · doi:10.1016/j.ijhydene.2022.02.175 · Cited by 489
Hyaluronan: molecular size‐dependent signaling and biological functions in inflammation and cancer
Tavianatou, A., Caon, I., Franchi, M., Piperigkou, Z., Galesso, D., & Karamanos, N. K. (2019) · FEBS Journal · doi:10.1111/febs.14777 · Cited by 472
Wolf, K., Müller, R., Borgmann, S., Bröcker, E., & Friedl, P. (2003) · Blood · doi:10.1182/blood-2002-12-3791 · Cited by 442
Halliday, G. M. (2005) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2004.09.013 · Cited by 439
Wickens, K. L., Black, P., Stanley, T., Mitchell, E. A., Fitzharris, P., Tannock, G. W., Purdie, G., & Crane, J. (2008) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2008.07.011 · Cited by 432
The Interplay Between Keratinocytes and Immune Cells in the Pathogenesis of Psoriasis
Albanesi, C., Madonna, S., Gisondi, P., & Girolomoni, G. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01549 · Cited by 432
Antimicrobial peptides and wound healing: biological and therapeutic considerations
Mangoni, M. L., McDermott, A. M., & ZASLOFF, M. A. (2016) · Experimental Dermatology · doi:10.1111/exd.12929 · Cited by 427
Effects of probiotics on atopic dermatitis: a randomised controlled trial
Weston, S. (2005) · Archives of Disease in Childhood · doi:10.1136/adc.2004.060673 · Cited by 408
FISHER, M. S., & Kripke, M. L. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.4.1688 · Cited by 400
Chitosan based biocomposite scaffolds for bone tissue engineering
Sekaran, S., Saleth, L. R., & Selvamurugan, N. (2016) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2016.01.112 · Cited by 384
Role of lipids in the formation and maintenance of the cutaneous permeability barrier
Feingold, K. R., & Elias, P. M. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2013.11.007 · Cited by 383
Kant, V., Gopal, A., Pathak, N. N., Kumar, P., Tandan, S. K., & Kumar, D. (2014) · International Immunopharmacology · doi:10.1016/j.intimp.2014.03.009 · Cited by 366
Kennedy, E. A., Connolly, J., Hourihane, J. O., Fallon, P. G., McLean, W. H. I., Murray, D. M., Jo, J., Segre, J. A., Kong, H. H., & Irvine, A. D. (2016) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2016.07.029 · Cited by 359
Hyaluronan in wound healing: Rediscovering a major player
Aya, K., & Stern, R. (2014) · Wound Repair and Regeneration · doi:10.1111/wrr.12214 · Cited by 339
Skin-Associated Lymphoid Tissues (SALT): Origins and Functions.
Streilein, J. W. (1983) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12536743 · Cited by 339
PhytAMP: a database dedicated to antimicrobial plant peptides
Hammami, R., Hamida, J. B., Vergoten, G., & Fliss, I. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn655 · Cited by 334
Photoimmunology: how ultraviolet radiation affects the immune system
Bernard, J. J., Gallo, R. L., & Krutmann, J. (2019) · Nature Reviews Immunology · doi:10.1038/s41577-019-0185-9 · Cited by 329
Görgüç, A., Gençdağ, E., & Yılmaz, F. M. (2020) · Food Research International · doi:10.1016/j.foodres.2020.109504 · Cited by 326
The Antimicrobial Properties of Melanocytes, Melanosomes and Melanin and the Evolution of Black Skin
Mackintosh, J. A. (2001) · Journal of Theoretical Biology · doi:10.1006/jtbi.2001.2331 · Cited by 313
Alemdaroğlu, C., Değim, Z., Çelebi, N., Zor, F., Öztürk, S., & Erdoğan, D. (2006) · Burns · doi:10.1016/j.burns.2005.10.015 · Cited by 313
Natural and Modified (1→3)-β-D-Glucans in Health Promotion and Disease Alleviation
Zeković, D. B., Kwiatkowski, S., Vrvić, M. M., Jakovljević, D. M., & Moran, C. A. (2005) · Critical Reviews in Biotechnology · doi:10.1080/07388550500376166 · Cited by 310
Effect of Antioxidants Supplementation on Aging and Longevity
Sadowska‐Bartosz, I., & Bartosz, G. (2014) · BioMed Research International · doi:10.1155/2014/404680 · Cited by 307
The Innate Immune System in Acute and Chronic Wounds
MacLeod, A. S., & Mansbridge, J. N. (2016) · Advances in Wound Care · doi:10.1089/wound.2014.0608 · Cited by 289
Regulation of Immune Function by Polyphenols
Ding, S., Jiang, H., & Fang, J. Q. (2018) · Journal of Immunology Research · doi:10.1155/2018/1264074 · Cited by 286
Antioxidants from Plants Protect against Skin Photoaging
Petruk, G., Del Giudice, R., Rigano, M. M., & Monti, D. M. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/1454936 · Cited by 283
Frosali, S., Pagliari, D., Gambassi, G., Landolfi, R., Pandolfi, F., & Cianci, R. (2015) · Journal of Immunology Research · doi:10.1155/2015/489821 · Cited by 281
Alginate based bilayer hydrocolloid films as potential slow-release modern wound dressing
Thu, H. E., Zulfakar, M. H., & Ng, S. (2012) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2012.05.044 · Cited by 271
Resveratrol for breast cancer prevention and therapy: Preclinical evidence and molecular mechanisms
Sinha, D., Sarkar, N., Biswas, J., & Bishayee, A. (2016) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2015.11.001 · Cited by 265
Burkatovskaya, M., Tegos, G. P., Swietlik, E. M., et al. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.03.028 · Cited by 263
Natural Polysaccharide Nanomaterials: An Overview of Their Immunological Properties
Torres, F. G., Troncoso, O. P., Pisani, A., Gatto, F., & Bardi, G. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20205092 · Cited by 263
Hsieh, F.-C., Lee, C.-L., Chai, C., Chen, W., Lu, Y.-C., & Wu, C. (2013) · Nutrition & Metabolism · doi:10.1186/1743-7075-10-35 · Cited by 262
Bioactive peptides derived from marine sources: Biological and functional properties
Cunha, S. A., & Pintado, M. (2021) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2021.08.017 · Cited by 261
Self-citationDysregulation of mucosal immune response in pathogenesis of inflammatory bowel disease
Xu, X. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i12.3255 · Cited by 252
Avenanthramides, polyphenols from oats, exhibit anti-inflammatory and anti-itch activity
Sur, R., Nigam, A., Grote, D., Liebel, F., & Southall, M. D. (2008) · Archives of Dermatological Research · doi:10.1007/s00403-008-0858-x · Cited by 240
The emerging roles of serine protease cascades in the epidermis
Ovaere, P., Lippens, S., Vandenabeele, P., & Declercq, W. (2009) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2009.08.001 · Cited by 238
The Use of Lentinan for Treating Gastric Cancer
Ina, K., Kataoka, T., & Ando, T. (2013) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/1871520611313050002 · Cited by 237
Perdiguero, E., Sousa-Victor, P., Ruiz-Bonilla, V., Jardí, M., Caelles, C., Serrano, A. L., & Muñoz-Cánoves, P. (2011) · Journal of Cell Biology · doi:10.1083/jcb.201104053 · Cited by 236
Natsuaki, Y., Egawa, G., Nakamizo, S., Ono, S., Hanakawa, S., Okada, T., Kusuba, N., Otsuka, A., Kitoh, A., Honda, T., et al. (2014) · Nature Immunology · doi:10.1038/ni.2992 · Cited by 232
LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery
van Smeden, J., Hoppel, L., van der Heijden, R., Hankemeier, T., Vreeken, R. J., & Bouwstra, J. A. (2011) · Journal of Lipid Research · doi:10.1194/jlr.m014456 · Cited by 229
Human immunology and immunotherapy: main achievements and challenges
Varadé, J., Magadán, S., & González‐Fernández, Á. (2020) · Cellular and Molecular Immunology · doi:10.1038/s41423-020-00530-6 · Cited by 228
UV Damage and DNA Repair in Malignant Melanoma and Nonmelanoma Skin Cancer
Rass, K., & Reichrath, J. (2009) · Advances in experimental medicine and biology · doi:10.1007/978-0-387-77574-6_13 · Cited by 220
A systematic review on the Rosa canina effect and efficacy profiles
Chrubasik, C., Roufogalis, B. D., Müller‐Ladner, U., & Chrubasik, S. (2008) · Phytotherapy Research · doi:10.1002/ptr.2400 · Cited by 220
Peptide synthesis: chemical or enzymatic
Guzmán, F., Barberis, S. E., & Illanes, A. (2007) · Electronic Journal of Biotechnology · doi:10.2225/vol10-issue2-fulltext-13 · Cited by 220
Sahle, F. F., Gebre‐Mariam, T., Dobner, B., Wohlrab, J., & Neubert, R. H. H. (2014) · Skin Pharmacology and Physiology · doi:10.1159/000360009 · Cited by 216
Danby, S. G., AlEnezi, T., Sultan, A., Lavender, T., Chittock, J., Brown, K., & Cork, M. J. (2013) · Pediatric Dermatology · doi:10.1111/j.1525-1470.2012.01865.x · Cited by 215
Skin lipids in health and disease: A review
Knox, S. E., & O’Boyle, N. M. (2021) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2021.105055 · Cited by 214
Du, B., Bian, Z., & Xu, B. (2013) · Phytotherapy Research · doi:10.1002/ptr.4963 · Cited by 208
Bacterial Sphingomyelinases and Phospholipases as Virulence Factors
Flores-Dı́az, M., Monturiol‐Gross, L., Naylor, C. E., Alape‐Girón, A., & Flieger, A. (2016) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00082-15 · Cited by 208
Ribeiro Barros Cardoso, C., Aparecida Souza, M., Amália Vieira Ferro, E., Favoreto, S., & Deolina Oliveira Pena, J. (2004) · Wound Repair and Regeneration · doi:10.1111/j.1067-1927.2004.012216.x · Cited by 207
Kodali, V. P., & Sen, R. (2008) · Biotechnology Journal · doi:10.1002/biot.200700208 · Cited by 207
Tian, R., Qiu, X., Yuan, P., Lei, K. C., Wang, L., Bai, Y., Liu, S., & Chen, X. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b01740 · Cited by 202
Huang, X., Sun, J. M., Chen, G., Niu, C., Wang, Y., Congcong, Z., Sun, J., Huang, H., Huang, S., Liang, Y., et al. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00421 · Cited by 202
A Comprehensive Review of Natural Compounds for Wound Healing: Targeting Bioactivity Perspective
Trinh, T. X., Long, N. V., Anh, L. T. V., Nga, P. T., Giang, N. N., Chien, P. N., Nam, S., & Heo, C. Y. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23179573 · Cited by 202
Probiotic Bacteria Induce a ‘Glow of Health’
Levkovich, T., Poutahidis, T., Smillie, C. S., Varian, B. J., Ibrahim, Y. M., Lakritz, J. R., Alm, E. J., & Erdman, S. E. (2013) · PLoS ONE · doi:10.1371/journal.pone.0053867 · Cited by 201
Commensal microbiota modulate gene expression in the skin
Meisel, J. S., Sfyroera, G., Bartow-McKenney, C., Gimblet, C., Bugayev, J., Horwinski, J., Kim, B., Brestoff, J. R., Tyldsley, A. S., Zheng, Q., et al. (2018) · Microbiome · doi:10.1186/s40168-018-0404-9 · Cited by 201
Li, S., Zhu, G., Yang, Y., Jian, Z., Guo, S., Dai, W., Shi, Q., Ge, R., Ma, J., Liu, L., et al. (2016) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2016.10.013 · Cited by 200
An insight into anti-inflammatory effects of fungal beta-glucans
Du, B., Lin, C., Bian, Z., & Xu, B. (2015) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2014.09.002 · Cited by 193
Fruit Oils: Chemistry and Functionality
Ramadan, M. F. (2019) · Springer eBooks · doi:10.1007/978-3-030-12473-1 · Cited by 192
The effect of probiotics on immune regulation, acne, and photoaging
Kober, M.-M., & Bowe, W. P. (2015) · International Journal of Women’s Dermatology · doi:10.1016/j.ijwd.2015.02.001 · Cited by 190
Targeting the gut‐skin axis—Probiotics as new tools for skin disorder management?
Szántó, M., Dózsa, A., Antal, D., Szabó, K., Kemény, L., & Bai, P. (2019) · Experimental Dermatology · doi:10.1111/exd.14016 · Cited by 189
Karim, A. A., Azlan, A., Ismail, A., Hashim, P., Gani, S. S. A., Zainudin, B. H., & Abdullah, N. A. (2014) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-14-381 · Cited by 184
Preparation, characterization, and biological properties of β-glucans
Rahar, S., Swami, G., Nagpal, N., Nagpal, M., & Singh, G. (2011) · Journal of Advanced Pharmaceutical Technology amp Research · doi:10.4103/2231-4040.82953 · Cited by 184
Piovesana, S., Capriotti, A. L., Cavaliere, C., Barbera, G. L., Montone, C. M., Chiozzi, R. Z., & Laganà, A. (2018) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-018-0852-x · Cited by 183
The role of sphingolipid metabolism in cutaneous permeabilitybarrier formation
Breiden, B., & Sandhoff, K. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2013.08.010 · Cited by 181
Evangelista, M. T. P., Abad-Casintahan, F., & Lopez-Villafuerte, L. (2014) · International Journal of Dermatology · doi:10.1111/ijd.12339 · Cited by 180
In vitro sun protection factor determination of herbal oils used in cosmetics
Saraf, S., & Kaur, C. D. (2010) · Pharmacognosy Research · doi:10.4103/0974-8490.60586 · Cited by 179
Vitamin C promotes wound healing through novel pleiotropic mechanisms
Mohammed, B. M., Fisher, B. J., Kraskauskas, D., Ward, S. I., Wayne, J. S., Brophy, D. F., Fowler, A. A., Yager, D. R., & Natarajan, R. (2015) · International Wound Journal · doi:10.1111/iwj.12484 · Cited by 177
Sikareepaisan, P., Ruktanonchai, U., & Supaphol, P. (2010) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2010.09.048 · Cited by 176
Effect of oleic and linoleic acids on the inflammatory phase of wound healing in rats
Pereira, L. M., Hatanaka, E., Martins, E. F., de Oliveira, F., Liberti, É. A., Farsky, S. H. P., Curi, R., & Pithon‐Curi, T. C. (2007) · Cell Biochemistry and Function · doi:10.1002/cbf.1432 · Cited by 175
Organ-specific immune responses associated with infectious disease
Engwerda, C. R., & Kaye, P. M. (2000) · Immunology Today · doi:10.1016/s0167-5699(99)01549-2 · Cited by 175
Aging-associated alterations in epidermal function and their clinical significance
Wang, Z., Man, M.-Q., Li, T., Elias, P. M., & Mauro, T. M. (2020) · Aging · doi:10.18632/aging.102946 · Cited by 175
Oleic acid modulation of the immune response in wound healing: A new approach for skin repair
Cardoso, C. R. D. B., Favoreto, S., de Oliveira, L. L., Vancim, J. O., Barban, G. B., Ferraz, D. B., & Silva, J. S. (2010) · Immunobiology · doi:10.1016/j.imbio.2010.06.007 · Cited by 174
Ellis, L. Z., Liu, W., Luo, Y., Okamoto, M., Qu, D., Dunn, J. H., & Fujita, M. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.09.115 · Cited by 173
Novel chitosan wound dressing loaded with minocycline for the treatment of severe burn wounds
Aoyagi, S., Onishi, H., & Machida, Y. (2006) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2006.09.016 · Cited by 173
Current Trends in Advanced Alginate-Based Wound Dressings for Chronic Wounds
Barbu, A., Neamtu, B. M., Zăhan, M., Iancu, G. M., Bacila, C. I., & Mireşan, V. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11090890 · Cited by 166
Wölfle, U., Esser, P. R., Simon-Haarhaus, B., Martin, S. F., Lademann, J. M., & Schempp, C. M. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.01.027 · Cited by 165
Byrne, S. N., Limón-Flores, A. Y., & Ullrich, S. E. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.7.4648 · Cited by 162
The Complexity of Fungal β-Glucan in Health and Disease: Effects on the Mononuclear Phagocyte System
Camilli, G., Tabouret, G., & Quintin, J. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00673 · Cited by 162
The use of hyaluronic acid based dressings to treat burns: A review
Longinotti, C. (2014) · Burns & Trauma · doi:10.4103/2321-3868.142398 · Cited by 157
Marine Polysaccharides for Wound Dressings Application: An Overview
Shen, S., Chen, X., Shen, Z., & Chen, H. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13101666 · Cited by 157
Weiss, G., Rasmussen, S., Zeuthen, L., Nielsen, B. N., Jarmer, H. Ø., Jespersen, L., & Frøkiær, H. (2010) · Immunology · doi:10.1111/j.1365-2567.2010.03301.x · Cited by 156
Lipid Disturbances in Psoriasis: An Update
Pietrzak, A., Michalak-Stoma, A., Chodorowska, G., & Szepietowski, J. C. (2010) · Mediators of Inflammation · doi:10.1155/2010/535612 · Cited by 156
Cheng, N., Lin, W.-J., Ling, T., et al. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2017.01.060 · Cited by 156
Knackstedt, R. W., Knackstedt, T., & Gatherwright, J. R. (2019) · Experimental Dermatology · doi:10.1111/exd.14032 · Cited by 156
Mayser, P. A., Mrowietz, U., Arenberger, P., et al. (1998) · Journal of the American Academy of Dermatology · doi:10.1016/s0190-9622(98)70114-8 · Cited by 149
Organization of the skin immune system and compartmentalized immune responses in infectious diseases
Quaresma, J. A. S. (2019) · Clinical Microbiology Reviews · doi:10.1128/cmr.00034-18 · Cited by 149
Meaume, S., Vallet, D., Morere, M. N., & Téot, L. (2005) · Journal of Wound Care · doi:10.12968/jowc.2005.14.9.26835 · Cited by 148
Skin lipids and epidermal differentiation in atopic dermatitis
Proksch, E., Jensen, J., & Elias, P. M. (2003) · Clinics in Dermatology · doi:10.1016/s0738-081x(02)00370-x · Cited by 146
Evaluation of wound healing activity of ferulic acid in diabetic rats
Ghaisas, M. M., Kshirsagar, S. B., & Sahane, R. (2012) · International Wound Journal · doi:10.1111/j.1742-481x.2012.01119.x · Cited by 143
β-Glucans: Multi-Functional Modulator of Wound Healing
Majtán, J., & Jeseňák, M. (2018) · Molecules · doi:10.3390/molecules23040806 · Cited by 142
Ní Raghallaigh, S., Bender, K., Lacey, N., Brennan, L., & Powell, F. C. (2012) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2011.10662.x · Cited by 138
Natural Polysaccharides with Immunomodulatory Activities
Zhao, Y., Yan, B., Wang, Z., Li, M., & Zhao, W. G. (2019) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/1389557519666190913151632 · Cited by 138
Bourguignon, L. (2014) · American Journal Of Pathology · doi:10.1016/j.ajpath.2014.03.010 · Cited by 137
Xu, M., Li, J., Lee, Y., Wu, Y., Liu, K., Shi, Y., An, H., Zhang, J.-R., Wang, X., Lai, Y., et al. (2018) · Immunity · doi:10.1016/j.immuni.2018.03.019 · Cited by 136
Oral Probiotic Control Skin Inflammation by Acting on Both Effector and Regulatory T Cells
Hacini‐Rachinel, F., Gheit, H., Luduec, J.-B. L., Dif, F., Nancey, S., & Kaiserlian, D. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004903 · Cited by 131
Wang, Z., Mascarenhas, N., Eckmann, L., Miyamoto, Y., Sun, X., Kawakami, T., & Nardo, A. D. (2016) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2016.09.019 · Cited by 130
Potapovich, A. I., Lulli, D., Fidanza, P., Kostyuk, V. A., Luca, C. D., Pastore, S., & Korkina, L. G. (2011) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2011.06.007 · Cited by 129
Lipid-based formulations in cosmeceuticals and biopharmaceuticals
Ahmad, A., & Ahsan, H. (2020) · Biomedical Dermatology · doi:10.1186/s41702-020-00062-9 · Cited by 129
Immunomodulatory Effects of Green Tea Polyphenols
Wang, S., Li, Z., Ma, Y., Liu, Y., Lin, C., Li, S., Zhan, J., & Ho, C. (2021) · Molecules · doi:10.3390/molecules26123755 · Cited by 128
Modulation of TGFβ1-Dependent Myofibroblast Differentiation by Hyaluronan
Webber, J. P., Jenkins, R. L., Meran, S., Phillips, A. O., & Steadman, R. (2009) · American Journal Of Pathology · doi:10.2353/ajpath.2009.080837 · Cited by 127
A randomized trial of Lactobacillus plantarum CJLP 133 for the treatment of atopic dermatitis
Han, Y., Kim, B., Ban, J., Lee, J., Kim, B. J., Choi, B. S., Hwang, S., Ahn, K., & Kim, J. (2012) · Pediatric Allergy and Immunology · doi:10.1111/pai.12010 · Cited by 127
Quercetin promotes cutaneous wound healing in mice through Wnt/β-catenin signaling pathway
Mi, Y., Zhong, L., Lu, S., Hu, P., Pan, Y., Ma, X., Yan, B., Wei, Z., & Yang, G. (2022) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2022.115066 · Cited by 127
The role of topical probiotics on wound healing: A review of animal and human studies
Knackstedt, R. W., Knackstedt, T., & Gatherwright, J. R. (2020) · International Wound Journal · doi:10.1111/iwj.13451 · Cited by 125
Hong, S. W., Choi, E. B., Min, T.-K., Kim, J.-H., Kim, M.-H., Jeon, S. G., Lee, B., Gho, Y. S., Jee, Y., Pyun, B.-Y., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0100499 · Cited by 124
Effect of Probiotics on the Treatment of Children with Atopic Dermatitis
Yeşilova, Y., Çalka, Ö., Akdeniz, N., & Berktaş, M. (2012) · Annals of Dermatology · doi:10.5021/ad.2012.24.2.189 · Cited by 118
Gut microbiota and immunity relevance in eubiosis and dysbiosis
Al-Rashidi, H. E. (2021) · Saudi Journal of Biological Sciences · doi:10.1016/j.sjbs.2021.10.068 · Cited by 116
Association of Alzheimer disease pathology with abnormal lipid metabolism
Matsuzaki, T., Sasaki, K., Hata, J., Hirakawa, Y., Fujimi, K., Ninomiya, T., Suzuki, S. O., Kanba, S., Kiyohara, Y., & Iwaki, T. (2011) · Neurology · doi:10.1212/wnl.0b013e31822e145d · Cited by 114
Sjövall, P., Skedung, L., Grégoire, S., Biganska, O., Clément, F., & Luengo, G. S. (2018) · Scientific Reports · doi:10.1038/s41598-018-34286-x · Cited by 113
Donato-Trancoso, A., Monte-Alto-Costa, A., & Romana-Souza, B. (2016) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2016.03.012 · Cited by 112
Buranasudja, V., Rani, D., Malla, A., Kobtrakul, K., & Vimolmangkang, S. (2021) · Scientific Reports · doi:10.1038/s41598-021-92958-7 · Cited by 112
Byrne, S. N., & Halliday, G. M. (2005) · Journal of Investigative Dermatology · doi:10.1111/j.0022-202x.2005.23615.x · Cited by 111
Characterization of Rosehip (Rosa canina L.) Seed and Seed Oil
Ilyasoğlu, H. (2014) · International Journal of Food Properties · doi:10.1080/10942912.2013.777075 · Cited by 111
Williams, A. R., Krych, Ł., Ahmad, H. F., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0186546 · Cited by 111
Three-Dimensional Printing of Soy Protein Scaffolds for Tissue Regeneration
Chien, K. B., Makridakis, E., & Shah, R. N. (2012) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2012.0383 · Cited by 110
Chabala, L. F. G., Echeverri-Cuartas, C. E., & López, M. E. L. (2017) · Marine Drugs · doi:10.3390/md15100328 · Cited by 110
Marzio, L. D., Cinque, B., Simone, C. D., & Cifone, M. G. (1999) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.1999.00633.x · Cited by 108
Liu, Y., Zongyuan, Y., Cheng, G., Lingyun, Z., Yu, G., & Wei, G. (2014) · Cancer Science · doi:10.1111/cas.12395 · Cited by 108
Tang, S., Liao, P.-Y., Hung, S., Ge, J., Chen, S.-M., Lai, J.-C., Hsiao, Y., & Yang, J. (2017) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2017.03.004 · Cited by 107
Chen, C.-L., Liou, S., Chen, S.-J., & Shih, M. (2011) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2011.03.001 · Cited by 106
Pastore, S., Lulli, D., Fidanza, P., Potapovich, A. I., Kostyuk, V. A., Luca, C. D., Mikhalchik, E. V., & Korkina, L. G. (2011) · Antioxidants and Redox Signaling · doi:10.1089/ars.2011.4053 · Cited by 106
Zhou, X., Dong, Q., Kan, X., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0204152 · Cited by 105
Drago, L., Iemoli, E., Rodighiero, V., Nicola, L., Vecchi, E. D., & Piconi, S. (2011) · International Journal of Immunopathology and Pharmacology · doi:10.1177/039463201102400421 · Cited by 104
Huang, Y., Zhu, Q., Yang, X., Xu, H., Sun, B., Wang, X., & Sheng, J. (2018) · The FASEB Journal · doi:10.1096/fj.201800337r · Cited by 103
Lehtoranta, L., Latvala, S., & Lehtinen, M. J. (2020) · Nutrients · doi:10.3390/nu12103163 · Cited by 103
Ribeiro, D., Carvalho, A. R., de Macedo, G. H. R. V., Chagas, V. L., da Silva, L. F. M., Cutrim, B. D. S., Santos, D. M., Soares, B. L. L., Zagmignan, A., de Miranda, R. D. C. M., et al. (2019) · Biomolecules · doi:10.3390/biom10010063 · Cited by 100
Vitamin C–squalene bioconjugate promotes epidermal thickening and collagen production in human skin
Gref, R., Deloménie, C., Maksimenko, A., Gouadon, E., Percoco, G., Lati, E., Desmaële, D., Zouhiri, F., & Couvreur, P. (2020) · Scientific Reports · doi:10.1038/s41598-020-72704-1 · Cited by 97
Kim, M., Oh, G., Kim, M., & Hwang, J. (2013) · Photochemistry and Photobiology · doi:10.1111/php.12061 · Cited by 96
Matsumoto, Y., & Kuroyanagi, Y. (2010) · Journal of Biomaterials Science Polymer Edition · doi:10.1163/156856209x435844 · Cited by 95
Wu, K.-G., Li, T.-H., & Peng, H. (2011) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2011.10596.x · Cited by 94
Lebre, M. C., Antons, J. C., Kaliński, P., Schuitemaker, J. H. N., van Capel, T. M. M., Kapsenberg, M. L., & de Jong, E. C. (2003) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2003.12245.x · Cited by 93
Phagocytosis by Normal Human Melanocytes in Vitro
Poole, I. C. L., van den Wijngaard, R. M., Westerhof, W., VERKRUISEN, R. P., Dutrieux, R. P., Dingemans, K. P., & Das, P. K. (1993) · Experimental Cell Research · doi:10.1006/excr.1993.1102 · Cited by 93
Isolation and characterization of diverse microbial representatives from the human skin microbiome
Timm, C. M., Loomis, K. H., Stone, W., Mehoke, T. S., Brensinger, B. R., Pellicore, M. J., Staniczenko, P. P. A., Charles, C., Nayak, S., & Karig, D. (2020) · Microbiome · doi:10.1186/s40168-020-00831-y · Cited by 93
Green Tea Polyphenol EGCG Sensing Motif on the 67-kDa Laminin Receptor
Fujimura, Y., Sumida, M., Sugihara, K., Tsukamoto, S., Yamada, K., & Tachibana, H. (2012) · PLoS ONE · doi:10.1371/journal.pone.0037942 · Cited by 90
Protective Mechanisms of Green Tea Polyphenols in Skin
Oyetakin‐White, P., Tribout, H., & Baron, E. D. (2012) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2012/560682 · Cited by 90
Apone, F., Barbulova, A., & Colucci, M. G. (2019) · Frontiers in Plant Science · doi:10.3389/fpls.2019.00756 · Cited by 90
Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy
Errante, F., Ledwoń, P., Latajka, R., Rovero, P., & Papini, A. M. (2020) · Frontiers in Chemistry · doi:10.3389/fchem.2020.572923 · Cited by 90
Novel jojoba oil-based emulsion gel formulations for clotrimazole delivery
Shahin, M., Abdel Hady, S., Hammad, M., & Mortada, N. (2011) · AAPS PharmSciTech · doi:10.1208/s12249-011-9583-4 · Cited by 88
Mack Correa, M. C., Mao, G., Saad, P., Flach, C. R., Mendelsohn, R., & Walters, R. M. (2014) · Experimental Dermatology · doi:10.1111/exd.12296 · Cited by 87
The chemistry, function and (patho)physiology of stratum corneum barrier ceramides
Moore, D. J., & Rawlings, A. V. (2017) · International Journal of Cosmetic Science · doi:10.1111/ics.12399 · Cited by 87
Sun, L. N., Jiang, W., Zhang, H., Guo, Y., Chen, W., Jin, Y., Chen, H., Du, K., Dai, H., Ji, J., et al. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b19522 · Cited by 87
Dainichi, T., Matsumoto, R., Mostafa, A., & Kabashima, K. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01107 · Cited by 87
Polyphenols as Immunomodulatory Compounds in the Tumor Microenvironment: Friends or Foes?
Focaccetti, C., Izzi, V., Benvenuto, M., Fazi, S., Ciuffa, S., Giganti, M. G., Potenza, V., Manzari, V., Modesti, A., & Bei, R. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20071714 · Cited by 86
Bioactive Lipids and Their Derivatives in Biomedical Applications
Park, J.-W., Choi, J., Kim, D., Lee, S., Lee, B., Lee, Y., Kim, S., Kwon, S., Noh, M., Lee, M., et al. (2021) · Biomolecules & Therapeutics · doi:10.4062/biomolther.2021.107 · Cited by 86
Lactobacilli and bifidobacteria induce differential interferon-β profiles in dendritic cells
Weiss, G., Christensen, H. R., Zeuthen, L., Vogensen, F. K., Jakobsen, M., & Frøkiær, H. (2011) · Cytokine · doi:10.1016/j.cyto.2011.07.024 · Cited by 84
The impact of quercetin on wound healing relates to changes in αV and β1 integrin expression
Doersch, K., & Newell‐Rogers, M. K. (2017) · Experimental Biology and Medicine · doi:10.1177/1535370217712961 · Cited by 84
Notarte, K. I., Quimque, M. T. J., Macaranas, I., Khan, A., Pastrana, A. M., Villaflores, O. B., Arturo, H. C. P., Pilapil, D. Y. H., Tan, S. M., Wei, D., et al. (2023) · ACS Omega · doi:10.1021/acsomega.2c06451 · Cited by 84
Significance of Alterations in Plasma Lipid Profile Levels in Breast Cancer
Shah, F. D., Shukla, S. N., Shah, P. M., et al. (2008) · Integrative Cancer Therapies · doi:10.1177/1534735407313883 · Cited by 83
Effect of Semisolid Formulation of Persea Americana Mill (Avocado) Oil on Wound Healing in Rats
de Oliveira, A. P., Franco, E. D. S., Barreto, R. R., Cordeiro, D. P., de Melo, R. G., de Aquino, C. M. F., Silva, A. A. R. E., de Medeiros, P. L., da Silva, T. G., Góes, A. J. D. S., et al. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/472382 · Cited by 83
Drug evaluation: the C5a receptor antagonist PMX-53.
Köhl, J. (2006) · PubMed · Cited by 80
Lăcătuşu, I., Arsenie, L. V., Badea, G., Popa, O., Oprea, O., & Badea, N. M. (2018) · Industrial Crops and Products · doi:10.1016/j.indcrop.2018.06.083 · Cited by 80
Use of lipidomics to investigate sebum dysfunction in juvenile acne
Camera, E., Ludovici, M., Tortorella, S., Sinagra, J. L., Capitanio, B., Goracci, L., & Picardo, M. (2016) · Journal of Lipid Research · doi:10.1194/jlr.m067942 · Cited by 79
Noh, E., Kim, J.-M., Lee, H.-Y., Song, H.-K., Joung, S., Yang, H.-J., Kim, M. J., Kim, K.-S., & Lee, Y.-R. (2019) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-019-2724-0 · Cited by 79
The Protective Effects of Fucosterol Against Skin Damage in UVB-Irradiated Human Dermal Fibroblasts
Hwang, E., Park, S., Sun, Z., Shin, H., Lee, D., & Yi, T. (2013) · Marine Biotechnology · doi:10.1007/s10126-013-9554-8 · Cited by 77
Missala, I., Kassner, U., & Steinhagen‐Thiessen, E. (2012) · International Journal of Rheumatology · doi:10.1155/2012/480784 · Cited by 76
Shen, T., Wang, G., You, L., Zhang, L., Ren, H., Hu, W., Qiang, Q., Wang, X., Ji, L., Gu, Z., et al. (2017) · Food & Nutrition Research · doi:10.1080/16546628.2017.1344523 · Cited by 76
Chitosan and Hydroxyapatite Based Biomaterials to Circumvent Periprosthetic Joint Infections
Costa-Pinto, A. R., Lemos, A. L., Tavaria, F. K., et al. (2021) · Materials · doi:10.3390/ma14040804 · Cited by 76
Self-citationAccelerated wound healing mediated by activation of Toll-like receptor 9
Sato, T., Yamamoto, M., Shimosato, T., & Klinman, D. M. (2010) · Wound Repair and Regeneration · doi:10.1111/j.1524-475x.2010.00632.x · Cited by 75
Lipiński, T., Fitieh, A. M., St‐Pierre, J., Ostergaard, H. L., Bundle, D. R., & Touret, N. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1202937 · Cited by 75
Wound Repair and Regeneration: Mechanisms, Signaling
Akita, S. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20246328 · Cited by 75
Wound healing activity of Persea americana(avocado) fruit: a preclinical study on rats
Nayak, B. S., Raju, S. S., & Chalapathi Rao, A. V. (2008) · Journal of Wound Care · doi:10.12968/jowc.2008.17.3.28670 · Cited by 74
Flagged first, then by citations
Research works printed but not linked: 5
- Boucetta, 2015, The effect of dietary and/or cosmetic argan oil on postmenopausal skin elasticity, Clin. Interv. Aging, 10, 339
- Kofuji, 2012, Antioxidant activity of beta-Glucan, ISRN Pharm., 2012
- Negi, 2020, Int. J. Res. Ppharmaceutic. Sci.
- Prasedya, 2020, Macroalgae sargassum cristaefolium extract inhibits proinflammatory cytokine expression in BALB/C Mice, Scientifica (Cairo), 2020
- Tavianatou, 2019, Hyaluronan: molecular size-dependent signaling and biological functions in inflammation and cancer, FEBS J., 286, 2883, 10.1111/febs.14777 · DOI
Cited by
Sorted by citations
Chronic Stress and Autoimmunity: The Role of HPA Axis and Cortisol Dysregulation
Nunez, S. G., Rabelo, S. P., Subotic, N., Caruso, J. W., & Knezevic, N. N. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26209994 · Cited by 138
“The skin is another major target of stress-induced immune alterations; cytokine imbalance in this context—mostly IL6 and TNFa—can delay wound healing and accelerate cutaneous aging [47].”
Cosmeceuticals in photoaging: A review.
Chan, L. K. W., Lee, K. W. A., Lee, C. H., Lam, K. W. P., Lee, K. F. V., Wu, R., Wan, J., Shivananjappa, S., Sky, W. T. H., Choi, H., et al. (2024) · Skin Research and Technology · doi:10.1111/srt.13730 · Cited by 23
“Overall, Fernandes et al.’s 50 systematic review offers a comprehensive overview of the current evidence on natural products for skin applications.”
BackgroundInfluential
Metadata
- Authors
- Fernandes, A., Rodrigues, P. M., Pintado, M., & Tavaria, F. K.
- Affiliations
- Universidade Católica Portuguesa (PT)
- Corresponding author
- Fernandes, A.
- Venue
- Phytomedicine
- Publisher
- Elsevier BV
- Published
- 2023-07
- Volume
- 115
- Pages
- 154824
- ISSN
- 0944-7113 (ISSN-L)
- OpenAlex
- W4366245600
- Cited by
- 264
- References
- 329
- Citations by year
- 2026: 91 · 2025: 95 · 2024: 60 · 2023: 18
- FWCI
- 12.15
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Phytomedicine (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, cc-by)
- Funders
- FCT (UIDB/50016/2020, UI/BD/151390/2021)
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Health Sciences › Medicine › Surgery › Wound Healing and Treatments
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Keywords
- natural products, skin care, skin inflammation, wound healing, photoaging, oxidative stress, skin microbiome, immunomodulation, polyphenols, polysaccharides, fatty acids, antimicrobial peptides, probiotics, atopic dermatitis, psoriasis, autoimmunity, dry skin, ultraviolet radiation, cosmeceuticals
- MeSH terms
- Anti-Inflammatory Agents, Antioxidants, Biological Products, Humans, Inflammation, Peptides, Polysaccharides, Skin Aging, Reactive Oxygen Species, Polyphenols
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
