Cited by 108Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration MechanismsConnexins and lens biology

The DOI matches its Crossref record; 375 of the 375 references it cites were found in a registry or an index.

Cell adhesion and matricellular support by astrocytes of the tripartite synapse

Open access

Hillen, Anne E.J., Burbach, J. Peter H., Hol, Elly M.·2018·Progress in Neurobiology

DOI 10.1016/j.pneurobio.2018.02.002

Open this paper in CoChat — free account Open PDF

Abstract

Astrocytes contribute to the formation, function, and plasticity of synapses. Their processes enwrap the neuronal components of the tripartite synapse, and due to this close interaction they are perfectly positioned to modulate neuronal communication. The interaction between astrocytes and synapses is facilitated by cell adhesion molecules and matricellular proteins, which have been implicated in the formation and functioning of tripartite synapses. The importance of such neuron-astrocyte integration at the synapse is underscored by the emerging role of astrocyte dysfunction in synaptic pathologies such as autism and schizophrenia. Here we review astrocyte-expressed cell adhesion molecules and matricellular molecules that play a role in integration of neurons and astrocytes within the tripartite synapse.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.pneurobio.2018.02.002

Cites

375 of 375 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Neurotoxic reactive astrocytes are induced by activated microglia
Liddelow, S. A., Guttenplan, K. A., Clarke, L. E., Bennett, F. C., Bohlen, C. J., Schirmer, L., Bennett, M. L., Münch, A. E., Chung, W.-S., Peterson, T. C., et al. (2017) · Nature · doi:10.1038/nature21029 · Cited by 7,971
Astrocytes: Biology and pathology
Sofroniew, M. V., & Vinters, H. V. (2010) · Acta Neuropathologica · doi:10.1007/s00401-009-0619-8 · Cited by 5,196
An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
Zhang, Y., Chen, K., Sloan, S. A., Bennett, M. L., Scholze, A. R., O'Keeffe, S., Phatnani, H. P., Guarnieri, P., Caneda, C., Ruderisch, N., et al. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.1860-14.2014 · Cited by 4,875
The Classical Complement Cascade Mediates CNS Synapse Elimination
Stevens, B., Allen, N. J., Vazquez, L. E., Howell, G. R., Christopherson, K. S., Nouri, N., Micheva, K. D., Mehalow, A. K., Huberman, A. D., Stafford, B., et al. (2007) · Cell · doi:10.1016/j.cell.2007.10.036 · Cited by 3,313
A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function
Cahoy, J. D., Emery, B., Kaushal, A., Foo, L. C., Zamanian, J. L., Christopherson, K. S., Xing, Y., Lubischer, J. L., Krieg, P. A., Krupenko, S. A., et al. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4178-07.2008 · Cited by 3,129
Tripartite synapses: glia, the unacknowledged partner
Araque, A., Parpura, V., Sanzgiri, R. P., & Haydon, P. G. (1999) · Trends in Neurosciences · doi:10.1016/s0166-2236(98)01349-6 · Cited by 2,529
Extracellular Matrix Degradation and Remodeling in Development and Disease
Lu, P., Takai, K., Weaver, V. M., & Werb, Z. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005058 · Cited by 2,265
Fibronectin at a glance
Pankov, R. G., & Yamada, K. M. (2002) · Journal of Cell Science · doi:10.1242/jcs.00059 · Cited by 2,055
Astrocyte scar formation aids central nervous system axon regeneration
Anderson, M. A., Burda, J. E., Ren, Y., Ao, Y., O’Shea, T. M., Kawaguchi, R., Coppola, G., Khakh, B. S., Deming, T. J., & Sofroniew, M. V. (2016) · Nature · doi:10.1038/nature17623 · Cited by 1,851
Synaptic scaling mediated by glial TNF-α
Stellwagen, D., & Malenka, R. C. (2006) · Nature · doi:10.1038/nature04671 · Cited by 1,715
CNS synaptogenesis promoted by glia-derived cholesterol
Mauch, D. H., Nägler, K., Schumacher, S., Göritz, C., Müller, E.-C., Otto, A., & Pfrieger, F. W. (2001) · Science · doi:10.1126/science.294.5545.1354 · Cited by 1,711
Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis
Christopherson, K. S., Ullian, E. M., Stokes, C. C. A., Mullowney, C. E., Hell, J. W., Agah, A., Lawler, J., Mosher, D. F., Bornstein, P., & Barres, B. A. (2005) · Cell · doi:10.1016/j.cell.2004.12.020 · Cited by 1,688
Protoplasmic Astrocytes in CA1 Stratum Radiatum Occupy Separate Anatomical Domains
Bushong, E. A., Martone, M. E., Jones, Y. Z., & Ellisman, M. H. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-01-00183.2002 · Cited by 1,578
Uniquely Hominid Features of Adult Human Astrocytes
Oberheim, N. A., Takano, T., Han, X., He, W., Lin, J. H. C., Wang, F., Xu, Q., Wyatt, J. D., Pilcher, W., Ojemann, J. G., et al. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.4707-08.2009 · Cited by 1,488
Long-term potentiation depends on release of d-serine from astrocytes
Henneberger, C., Papouin, T., Oliet, S. H. R., & Rusakov, D. A. (2010) · Nature · doi:10.1038/nature08673 · Cited by 1,389
Gliotransmitters Travel in Time and Space
Araque, A., Carmignoto, G., Haydon, P. G., Oliet, S. H. R., Robitaille, R., & Volterra, A. (2014) · Neuron · doi:10.1016/j.neuron.2014.02.007 · Cited by 1,308
Diversity of astrocyte functions and phenotypes in neural circuits
Khakh, B. S., & Sofroniew, M. V. (2015) · Nature Neuroscience · doi:10.1038/nn.4043 · Cited by 1,239
Extracellular matrix and cell signalling: the dynamic cooperation of integrin, proteoglycan and growth factor receptor
Kim, S., Turnbull, J. E., & Guimond, S. E. (2011) · Journal of Endocrinology · doi:10.1530/joe-10-0377 · Cited by 1,206
Saturated Reconstruction of a Volume of Neocortex
Kasthuri, N., Hayworth, K. J., Berger, D. R., Schalek, R. L., Conchello, J. A., Knowles-Barley, S., Lee, D., Vázquez-Reina, A., Kaynig, V., Jones, T. R., et al. (2015) · Cell · doi:10.1016/j.cell.2015.06.054 · Cited by 1,044
Neuronal Synchrony Mediated by Astrocytic Glutamate through Activation of Extrasynaptic NMDA Receptors
Fellin, T., Pascual, O., Gobbo, S., Pozzan, T., Haydon, P. G., & Carmignoto, G. (2004) · Neuron · doi:10.1016/j.neuron.2004.08.011 · Cited by 1,005
Three-Dimensional Relationships between Hippocampal Synapses and Astrocytes
Ventura, R. E., & Harris, K. M. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-16-06897.1999 · Cited by 907
Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis
Eroglu, Ç., Allen, N. J., Susman, M. W., O'Rourke, N. A., Park, C. Y., Özkan, E., Chakraborty, C., Mulinyawe, S. B., Annis, D. S., Huberman, A. D., et al. (2009) · Cell · doi:10.1016/j.cell.2009.09.025 · Cited by 893
The tripartite synapse: roles for gliotransmission in health and disease
Halassa, M. M., Fellin, T., & Haydon, P. G. (2007) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2006.12.005 · Cited by 852
Regulation of synaptic connectivity by glia.
Eroglu, C., & Barres, B. A. (2010) · Nature · doi:10.1038/nature09612 · Cited by 813 · cited 18×
“The regulation of the space between the synapse and the perisynaptic astrocyte processes (PAPs) determines the diffusion of signalling molecules, such as glutamate.”
BackgroundInfluential
Astrocytes: a central element in neurological diseases
Pekny, M., Pekna, M., Messing, A., Steinhäuser, C., Lee, J., Parpura, V., Hol, E. M., Sofroniew, M. V., & Verkhratsky, A. (2015) · Acta Neuropathologica · doi:10.1007/s00401-015-1513-1 · Cited by 793
Self-citation
Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors
Allen, N. J., Bennett, M. L., Foo, L. C., Wang, G. X., Chakraborty, C., Smith, S. J., & Barres, B. A. (2012) · Nature · doi:10.1038/nature11059 · Cited by 764
Astrocytes Potentiate Transmitter Release at Single Hippocampal Synapses
Perea, G., & Araque, A. (2007) · Science · doi:10.1126/science.1144640 · Cited by 727
EphB Receptors Interact with NMDA Receptors and Regulate Excitatory Synapse Formation
Dalva, M. B., Takasu, M. A., Lin, M. Z., Shamah, S. M., Hu, L. S., Gale, N. W., & Greenberg, M. E. (2000) · Cell · doi:10.1016/s0092-8674(00)00197-5 · Cited by 727
The Growth Cone Cytoskeleton in Axon Outgrowth and GuidancePreprint
Dent, E. W., Gupton, S. L., & Gertler, F. B. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a001800 · Cited by 692
Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC
Kucukdereli, H., Allen, N. J., Lee, A. T., Feng, A., Ozlu, M. I., Conatser, L. M., Chakraborty, C., Workman, G., Weaver, M., Sage, E. H., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1104977108 · Cited by 642 · cited 23×
“The regulation of the space between the synapse and the perisynaptic astrocyte processes (PAPs) determines the diffusion of signalling molecules, such as glutamate.”
BackgroundInfluential
Fibronectin Polymerization Regulates the Composition and Stability of Extracellular Matrix Fibrils and Cell-Matrix Adhesions
Sottile, J., & Hocking, D. C. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.e02-01-0048 · Cited by 637
Silent synapses and the emergence of a postsynaptic mechanism for LTP
Kerchner, G. A., & Nicoll, R. A. (2008) · Nature reviews. Neuroscience · doi:10.1038/nrn2501 · Cited by 635
Spatial organization of the extracellular matrix regulates cell–cell junction positioning
Tseng, Q., Duchemin-Pelletier, E., Deshière, A., Balland, M., Guillou, H., Filhol, O., & Théry, M. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1106377109 · Cited by 611
Synergistic control of cell adhesion by integrins and syndecans
Morgan, M. R., Humphries, M. J., & Bass, M. D. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2289 · Cited by 608
INTEGRIN STRUCTURE, ALLOSTERY, AND BIDIRECTIONAL SIGNALING
Arnaout, M. A., Mahalingam, B., & Xiong, J.-P. (2005) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.21.090704.151217 · Cited by 574
Activity-dependent structural and functional plasticity of astrocyte-neuron interactions
Theodosis, D. T., Poulain, D. A., & Oliet, S. H. R. (2008) · Physiological Reviews · doi:10.1152/physrev.00036.2007 · Cited by 531
Identification of diverse astrocyte populations and their malignant analogs
John Lin, C.-C., Yu, K., Hatcher, A., Huang, T.-W., Lee, H. K., Carlson, J., Weston, M. C., Chen, F., Zhang, Y., Zhu, W., et al. (2017) · Nature Neuroscience · doi:10.1038/nn.4493 · Cited by 525
Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signaling
Murai, K. K., Nguyen, L. N., Irie, F., Yamaguchi, Y., & Pasquale, E. B. (2003) · Nature Neuroscience · doi:10.1038/nn994 · Cited by 516
The Transcriptome and Metabolic Gene Signature of Protoplasmic Astrocytes in the Adult Murine Cortex
Lovatt, D., Sonnewald, U., Waagepetersen, H. S., Schousboe, A., He, W., Lin, J. H.-C., Han, X., Takano, T., Wang, S., Sim, F. J., et al. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.3404-07.2007 · Cited by 505
Laminins
Durbeej, M. (2009) · Cell and Tissue Research · doi:10.1007/s00441-009-0838-2 · Cited by 500
Specification and Morphogenesis of Astrocytes
Freeman, M. R. (2010) · Science · doi:10.1126/science.1190928 · Cited by 489
Aberrant differentiation of neuromuscular junctions in mice lacking s-laminin/laminin β2
Noakes, P., Gautam, M., Mudd, J., Sanes, J., & Merlie, J. (1995) · Nature · doi:10.1038/374258a0 · Cited by 474
The role of tenascin-C in tissue injury and tumorigenesis
Midwood, K. S., & Orend, G. (2009) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-009-0075-1 · Cited by 453
PSA-NCAM in mammalian structural plasticity and neurogenesis
Bonfanti, L. (2006) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2006.08.003 · Cited by 448
Fibronectins, Their Fibrillogenesis, and In Vivo FunctionsPreprint
Schwarzbauer, J. E., & DeSimone, D. W. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005041 · Cited by 445
Extrasynaptic Glutamate Diffusion in the Hippocampus: Ultrastructural Constraints, Uptake, and Receptor Activation
Rusakov, D. A., & Kullmann, D. M. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-09-03158.1998 · Cited by 438
High-Resolution Proteomics Unravel Architecture and Molecular Diversity of Native AMPA Receptor Complexes
Schwenk, J., Harmel, N., Brechet, A., Zolles, G., Berkefeld, H., Müller, C. S., Bildl, W., Baehrens, D., Hüber, B., Kulik, A., et al. (2012) · Neuron · doi:10.1016/j.neuron.2012.03.034 · Cited by 433
Bidirectional modulation of synaptic functions by Eph/ephrin signaling
Klein, R. (2008) · Nature Neuroscience · doi:10.1038/nn.2231 · Cited by 431
Specification of synaptic connectivity by cell surface interactions
de Wit, J., & Ghosh, A. (2015) · Nature reviews. Neuroscience · doi:10.1038/nrn.2015.3 · Cited by 415
Heterogeneity in astrocyte morphology and physiology
Matyash, V., & Kettenmann, H. (2009) · Brain Research Reviews · doi:10.1016/j.brainresrev.2009.12.001 · Cited by 413
The carbonic anhydrase domain of receptor tyrosine phosphatase β is a functional ligand for the axonal cell recognition molecule contactin
Peles, E., Nativ, M., Campbell, P. L., Sakurai, T., Martinez, R., Lev, S., Clary, D. O., Schilling, J., Barnea, G., Plowman, G. D., et al. (1995) · Cell · doi:10.1016/0092-8674(95)90312-7 · Cited by 397
Do glia drive synaptic and cognitive impairment in disease?
Chung, W.-S., Welsh, C. A., Barres, B. A., & Stevens, B. (2015) · Nature Neuroscience · doi:10.1038/nn.4142 · Cited by 385
Astroglial networks scale synaptic activity and plasticity
Pannasch, U., Vargová, L., Reingruber, J., Ezan, P., Holcman, D., Giaume, C., Syková, E., & Rouach, N. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1016650108 · Cited by 383
Laminin is produced by early rat astrocytes in primary culture.
Liesi, P., Dahl, D. R., & Vaheri, A. I. (1983) · The Journal of Cell Biology · doi:10.1083/jcb.96.3.920 · Cited by 382
Human CASK/LIN-2 Binds Syndecan-2 and Protein 4.1 and Localizes to the Basolateral Membrane of Epithelial Cells
Cohen, A. R., Wood, D. F., Marfatia, S. M., Walther, Z., Chishti, A. H., & Anderson, J. M. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.142.1.129 · Cited by 373
N-cadherin and integrins: Two receptor systems that mediate neuronal process outgrowth on astrocyte surfaces
Tomaselli, K. J., Neugebauer, K. M., Bixby, J. L., Lilien, J. E., & Reichard, L. F. (1988) · Neuron · doi:10.1016/0896-6273(88)90207-3 · Cited by 371
An Unbiased Expression Screen for Synaptogenic Proteins Identifies the LRRTM Protein Family as Synaptic Organizers
Linhoff, M. W., Laurén, J., Cassidy, R. M., Dobie, F. A., Takahashi, H., Nygaard, H. B., Airaksinen, M. S., Strittmatter, S. M., & Craig, A. M. (2009) · Neuron · doi:10.1016/j.neuron.2009.01.017 · Cited by 370
The adhesion molecule on glia (AMOG) is a homologue of the beta subunit of the Na,K-ATPase.
Gloor, S. M., Antonicek, H., Sweadner, K. J., Pagliusi, S. R., Frank, R. W., Moos, M., & Schachner, M. (1990) · The Journal of Cell Biology · doi:10.1083/jcb.110.1.165 · Cited by 363
Biochemical and functional characterization of the interaction between pentraxin 3 and C1q
Nauta, A. J., Bottazzi, B., Mantovani, A., Salvatori, G., Kishore, U., Schwaeble, W., Gingras, A. R., Tzima, S., Vivanco, F., Egido, J., et al. (2003) · European Journal of Immunology · doi:10.1002/immu.200310022 · Cited by 348
Connexin30 in rodent, cat and human brain: selective expression in gray matter astrocytes, co-localization with connexin43 at gap junctions and late developmental appearance
Nagy, J. I., Patel, D., Ochalski, P. A. Y., & Stelmack, G. L. (1999) · Neuroscience · doi:10.1016/s0306-4522(98)00191-2 · Cited by 346
Advances in tenascin-C biology
Midwood, K. S., Hussenet, T., Langlois, B., & Orend, G. (2011) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-011-0783-6 · Cited by 341
Composition of perineuronal nets in the adult rat cerebellum and the cellular origin of their components
Carulli, D., Rhodes, K. E., Brown, D. J., Bonnert, T. P., Pollack, S. J., Oliver, K., Strata, P., & Fawcett, J. W. (2006) · Journal of Comparative Neurology · doi:10.1002/cne.20822 · Cited by 341
Extracellular interactions between GluR2 and N-cadherin in spine regulation
Saglietti, L., Dequidt, C., Kamieniarz, K., Rousset, M.-C., Valnegri, P., Thoumine, O., Beretta, F., Fagni, L., Choquet, D., Sala, C., et al. (2007) · Neuron · doi:10.1016/j.neuron.2007.04.012 · Cited by 341
Axon Growth and Guidance: Receptor Regulation and Signal Transduction
O’Donnell, M. P., Chance, R. K., & Bashaw, G. J. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.051508.135614 · Cited by 340
Neuroligin‐3 is a neuronal adhesion protein at GABAergic and glutamatergic synapses
Budreck, E. C., & Scheiffele, P. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05842.x · Cited by 336
Connexin 30 sets synaptic strength by controlling astroglial synapse invasion
Pannasch, U., Freche, D., Dallérac, G. M., Ghézali, G., Escartin, C., Ezan, P., Cohen‐Salmon, M., Benchenane, K., Abudara, V., Dufour, A., et al. (2014) · Nature Neuroscience · doi:10.1038/nn.3662 · Cited by 329
Astrocytes Assemble Thalamocortical Synapses by Bridging NRX1α and NL1 via Hevin
Singh, S. K., Stogsdill, J. A., Pulimood, N. S., Dingsdale, H., Kim, Y. H., Pilaz, L., Kim, I. H., Manhães, A. C., Rodrigues, W. D. S., Pamukcu, A., et al. (2016) · Cell · doi:10.1016/j.cell.2015.11.034 · Cited by 324
Plasticity of Astrocytic Coverage and Glutamate Transporter Expression in Adult Mouse Cortex
Genoud, C., Quairiaux, C., Steiner, P., Hirling, H., Welker, E., & Knott, G. W. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040343 · Cited by 321
Cadherins in Brain Morphogenesis and Wiring
Hirano, S., & Takeichi, M. (2012) · Physiological Reviews · doi:10.1152/physrev.00014.2011 · Cited by 320
Narp regulates homeostatic scaling of excitatory synapses on parvalbumin-expressing interneurons
Chang, M. C., Park, J. M., Pelkey, K. A., Grabenstatter, H. L., Xu, D., Linden, D. J., Sutula, T. P., McBain, C. J., & Worley, P. F. (2010) · Nature Neuroscience · doi:10.1038/nn.2621 · Cited by 316
The role of integrin binding sites in fibronectin matrix assembly in vivo
Leiß, M., Beckmann, K., Girós, A., Costell, M., & Fässler, R. (2008) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2008.06.001 · Cited by 313
Astrogliosis: An integral player in the pathogenesis of Alzheimer's disease
Osborn, L. M., Kamphuis, W., Wadman, W. J., & Hol, E. M. (2016) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2016.01.001 · Cited by 312
Self-citation
EphB/syndecan-2 signaling in dendritic spine morphogenesis
Ethell, I. M., Irie, F., Kalo, M. S., Couchman, J. R., Pasquale, E. B., & Yamaguchi, Y. (2001) · Neuron · doi:10.1016/s0896-6273(01)00440-8 · Cited by 309
PKC Signaling Mediates Global Enhancement of Excitatory Synaptogenesis in Neurons Triggered by Local Contact with Astrocytes
Hama, H., Hara, C., Yamaguchi, K., & Miyawaki, A. (2004) · Neuron · doi:10.1016/s0896-6273(04)00007-8 · Cited by 300
Structural plasticity of perisynaptic astrocyte processes involves ezrin and metabotropic glutamate receptors
Lavialle, M., Aumann, G., Anlauf, E., Pröls, F., Arpin, M., & Derouiche, A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1100957108 · Cited by 283
Syndecans as receptors and organizers of the extracellular matrix
Xian, X., Gopal, S., & Couchman, J. (2009) · Cell and Tissue Research · doi:10.1007/s00441-009-0829-3 · Cited by 283
Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport
Filosa, A., Paixão, S., Honsek, S. D., Carmona, M. A., Becker, L., Feddersen, B., Gaitanos, L., Rudhard, Y., Schoepfer, R., Klopstock, T., et al. (2009) · Nature Neuroscience · doi:10.1038/nn.2394 · Cited by 283
Neuroligins Mediate Excitatory and Inhibitory Synapse Formation
Levinson, J. N., Chéry, N., Huang, K., Wong, T. P., Gerrow, K., Kang, R., Prange, O., Wang, Y. T., & El-Husseini, A. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m413812200 · Cited by 282
Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice
Orre, M., Kamphuis, W., Osborn, L. M., Melief, J., Kooijman, L., Huitinga, I., Klooster, J., Bossers, K., & Hol, E. M. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.07.008 · Cited by 279
Self-citation
A synaptic laminin–calcium channel interaction organizes active zones in motor nerve terminals
Nishimune, H., Sanes, J. R., & Carlson, S. S. (2004) · Nature · doi:10.1038/nature03112 · Cited by 276
Synaptic organizing complexes
Siddiqui, T. J., & Craig, A. M. (2010) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2010.08.016 · Cited by 276
Three-Dimensional analysis of dendritic spines
Špaček, J., & Hartmann, M. (1983) · Anatomy and Embryology · doi:10.1007/bf00298517 · Cited by 269
Diverse biological functions of the SPARC family of proteins
Bradshaw, A. D. (2012) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2011.12.021 · Cited by 268
Direct Astrocytic Contacts Regulate Local Maturation of Dendritic Spines
西田, 秀., & Okabe, S. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.4466-06.2007 · Cited by 268
Molecular signals of plasticity at the tetrapartite synapse
Dityatev, A., & Rusakov, D. A. (2011) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2010.12.006 · Cited by 267
Morphology and dynamics of perisynaptic glia
Reichenbach, A., Derouiche, A., & Kirchhoff, F. (2010) · Brain Research Reviews · doi:10.1016/j.brainresrev.2010.02.003 · Cited by 265
Narp and NP1 Form Heterocomplexes that Function in Developmental and Activity-Dependent Synaptic Plasticity
Xu, D., Hopf, C., Reddy, R., Cho, R. W., Guo, L., Lanahan, A., Petralia, R. S., Wenthold, R. J., O'Brien, R. J., & Worley, P. (2003) · Neuron · doi:10.1016/s0896-6273(03)00463-x · Cited by 265
Polysialylated Neural Cell Adhesion Molecule Promotes Remodeling and Formation of Hippocampal Synapses
Dityatev, A. E., Dityatev, A. E., Sytnyk, V., Delling, M., Toni, N., Nikonenko, I., Müller, D., & Schachner, M. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.1702-04.2004 · Cited by 265
Brevican-Deficient Mice Display Impaired Hippocampal CA1 Long-Term Potentiation but Show No Obvious Deficits in Learning and Memory
Brakebusch, C., Seidenbecher, C. I., Asztely, F., Rauch, U., Matthies, H., Meyer, H., Krug, M., Böckers, T. M., Zhou, X., Kreutz, M. R., et al. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.21.7417-7427.2002 · Cited by 264
Thrombospondins 1 and 2 are Necessary for Synaptic Plasticity and Functional Recovery after Stroke
Liauw, J. A., Hoang, S., Choi, M. Y., Eroğlu, Ç., Choi, M., Sun, G.-H., Percy, M., Wildman‐Tobriner, B., Bliss, T. M., Guzman, R. G., et al. (2008) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2008.65 · Cited by 263
Non-clustered protocadherin
Kim, S., Yasuda, S., Tanaka, H., Yamagata, K., & Kim, H. (2011) · Cell Adhesion & Migration · doi:10.4161/cam.5.2.14374 · Cited by 263
Astrocytes as a Source for Extracellular Matrix Molecules and Cytokines
Wiese, S., Karus, M., & Faissner, A. (2012) · Frontiers in Pharmacology · doi:10.3389/fphar.2012.00120 · Cited by 262
Interference of tenascin-C with syndecan-4 binding to fibronectin blocks cell adhesion and stimulates tumor cell proliferation.
Huang, W., Chiquet‐Ehrismann, R., Moyano, J. V., Garcı́a-Pardo, A., & Orend, G. (2001) · PubMed · Cited by 260
Signaling from Axon Guidance ReceptorsPreprint
Bashaw, G. J., & Klein, R. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a001941 · Cited by 260
The role of neurexins and neuroligins in the formation, maturation, and function of vertebrate synapses
Krueger‐Burg, D., Tuffy, L. P., Papadopoulos, T. G., & Brose, N. (2012) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2012.02.012 · Cited by 258
Synaptic Cell Adhesion
Missler, M., Sudhof, T. C., & Biederer, T. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005694 · Cited by 255
Emerging role for astroglial networks in information processing: from synapse to behavior
Pannasch, U., & Rouach, N. (2013) · Trends in Neurosciences · doi:10.1016/j.tins.2013.04.004 · Cited by 251
Pentraxins Coordinate Excitatory Synapse Maturation and Circuit Integration of Parvalbumin Interneurons
Pelkey, K. A., Barksdale, E., Craig, M. T., Yuan, X., Sukumaran, M., Vargish, G. A., Mitchell, R. M., Wyeth, M. S., Petralia, R. S., Chittajallu, R., et al. (2015) · Neuron · doi:10.1016/j.neuron.2015.02.020 · Cited by 245
Astrocyte-Synapse Structural Plasticity
Bernardinelli, Y., Müller, D., & Nikonenko, I. (2014) · Neural Plasticity · doi:10.1155/2014/232105 · Cited by 243
Molecular domains of myelinated axons.
Peles, E., & Salzer, J. (2000) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00122-7 · Cited by 242
Protocadherins
Frank, M., & Kemler, R. (2002) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(02)00365-4 · Cited by 242
Neuron-glia networks: integral gear of brain function
Perea, G., Sur, M., & Araque, A. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00378 · Cited by 241
The F3/11 cell adhesion molecule mediates the repulsion of neurons by the extracellular matrix glycoprotein J1-160/180
Pesheva, P., Gennarini, G., Goridis, C., & Schachner, M. (1993) · Neuron · doi:10.1016/0896-6273(93)90243-k · Cited by 241
Release of gliotransmitters through astroglial connexin 43 hemichannels is necessary for fear memory consolidation in the basolateral amygdala
Stehberg, J., Moraga‐Amaro, R., Salazar, C. M., Becerra, Á., Echeverría, C., Orellana, J. A., Bultynck, G., Ponsaerts, R., Leybaert, L., Simón, F., et al. (2012) · The FASEB Journal · doi:10.1096/fj.11-198416 · Cited by 238
Astrocyte-induced Synaptogenesis Is Mediated by Transforming Growth Factor β Signaling through Modulation of d-Serine Levels in Cerebral Cortex Neurons
Diniz, L. P., Almeida, J. C., Tortelli, V., Lopes, C. V., Setti-Perdigão, P., Stipursky, J., Kahn, S. A., Romão, L. F., Miranda, J. D., Alves‐Leon, S. V., et al. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.380824 · Cited by 237
Astrocytes and Therapeutics for Parkinson's Disease
Rappold, P. M., & Tieu, K. (2010) · Neurotherapeutics · doi:10.1016/j.nurt.2010.07.001 · Cited by 234
Role of astrocyte–synapse interactions in CNS disorders
Blanco‐Suárez, E., Caldwell, A. L. M., & Allen, N. J. (2016) · The Journal of Physiology · doi:10.1113/jp270988 · Cited by 234
Biochemical and functional characterization of a novel neuron-glia adhesion molecule that is involved in neuronal migration.
Antonicek, H., Persohn, E., & Schachner, M. (1987) · The Journal of Cell Biology · doi:10.1083/jcb.104.6.1587 · Cited by 233
Regulation of axonal outgrowth and pathfinding by integrin–ecm interactions
Myers, Santiago‐Medina, M., & Gomez, T. M. (2011) · Developmental Neurobiology · doi:10.1002/dneu.20931 · Cited by 229
The Brain Chondroitin Sulfate Proteoglycan Brevican Associates with Astrocytes Ensheathing Cerebellar Glomeruli and Inhibits Neurite Outgrowth from Granule Neurons
Yamada, H., Fredette, B. J., Shitara, K., Hagihara, K., Miura, R., Ranscht, B., Stallcup, W. B., & Yamaguchi, Y. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-20-07784.1997 · Cited by 228
Activity-Dependent Regulation of Synaptic AMPA Receptor Composition and Abundance by β3 Integrins
Cingolani, L. A., Thalhammer, A., Yu, L. M. Y., Catalano, M., Ramos, T., Colicos, M. A., & Goda, Y. (2008) · Neuron · doi:10.1016/j.neuron.2008.04.011 · Cited by 223
Neuronal Pentraxin 2 Supports Clear Cell Renal Cell Carcinoma by Activating the AMPA-Selective Glutamate Receptor-4
Roemeling, C. A. V., Radisky, D. C., Marlow, L. A., Cooper, S. J., Grebe, S. K. G., Anastasiadis, P. Z., Tun, H. W., & Copland, J. A. (2014) · Cancer Research · doi:10.1158/0008-5472.can-14-0210 · Cited by 222
Glial ephrin-A3 regulates hippocampal dendritic spine morphology and glutamate transport
Carmona, M. A., Murai, K. K., Wang, L., Roberts, A. J., & Pasquale, E. B. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0903328106 · Cited by 216
Fibronectin aggregation in multiple sclerosis lesions impairs remyelination
Stoffels, J. M. J., de Jonge, J. C., Stancic, M., Nomden, A., van Strien, M. E., Ma, D., Šišková, Z., Maier, O., ffrench‐Constant, C., Franklin, R. J. M., et al. (2013) · Brain · doi:10.1093/brain/aws313 · Cited by 214
Regulated Expression and Subcellular Localization of Syndecan Heparan Sulfate Proteoglycans and the Syndecan-Binding Protein CASK/LIN-2 during Rat Brain Development
Hsueh, Y., & Sheng, M. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-17-07415.1999 · Cited by 213
Contributions of astrocytes to synapse formation and maturation — Potential functions of the perisynaptic extracellular matrix
Faissner, A., Pyka, M., Geissler, M., Sobik, T., Frischknecht, R., Gundelfinger, E. D., & Seidenbecher, C. (2010) · Brain Research Reviews · doi:10.1016/j.brainresrev.2010.01.001 · Cited by 207
The signaling mechanisms of syndecan heparan sulfate proteoglycans
Lambaerts, K., Wilcox‐Adelman, S. A., & Zimmermann, P. (2009) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2009.05.002 · Cited by 205
Properly formed but improperly localized synaptic specializations in the absence of laminin α4
Patton, B., Cunningham, J. M., Thyboll, J., Kortesmaa, J., Westerblad, H., Edström, L., Tryggvason, K., & Sanes, J. (2001) · Nature Neuroscience · doi:10.1038/88414 · Cited by 203
Thrombospondin 1 accelerates synaptogenesis in hippocampal neurons through neuroligin 1
Xu, J., Xiao, N., & Xia, J. (2009) · Nature Neuroscience · doi:10.1038/nn.2459 · Cited by 203
Interaction of the N-Terminal Domain of the AMPA Receptor GluR4 Subunit with the Neuronal Pentraxin NP1 Mediates GluR4 Synaptic Recruitment
Sia, G.-M., Béïque, J.-C., Rumbaugh, G., Cho, R., Worley, P. F., & Huganir, R. L. (2007) · Neuron · doi:10.1016/j.neuron.2007.06.020 · Cited by 201
Integrins Control Dendritic Spine Plasticity in Hippocampal Neurons through NMDA Receptor and Ca2+/Calmodulin-Dependent Protein Kinase II-Mediated Actin Reorganization
Shi, Y., & Ethell, I. M. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.4091-05.2006 · Cited by 200
Neuromuscular synaptogenesis: coordinating partners with multiple functions
Darabid, H., Pérez-González, A., & Robitaille, R. (2014) · Nature reviews. Neuroscience · doi:10.1038/nrn3821 · Cited by 199
Activity-Induced Protocadherin Arcadlin Regulates Dendritic Spine Number by Triggering N-Cadherin Endocytosis via TAO2β and p38 MAP Kinases
Yasuda, S., Tanaka, H., Sugiura, H., Okamura, K., Sakaguchi, T., Tran, U., Takemiya, T., Mizoguchi, A., Yagita, Y., Sakurai, T., et al. (2007) · Neuron · doi:10.1016/j.neuron.2007.08.020 · Cited by 193
Three-dimensional analysis of dendritic spines
Špaček, J. (1985) · Anatomy and Embryology · doi:10.1007/bf00341419 · Cited by 193
ATP: A ubiquitous gliotransmitter integrating neuron–glial networks
Butt, A. M. (2011) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2011.02.023 · Cited by 191
Control of CNS Synapse Development by γ-Protocadherin-Mediated Astrocyte–Neuron Contact
Garrett, A. M., & Weiner, J. A. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.2818-09.2009 · Cited by 187
An LRRTM4-HSPG Complex Mediates Excitatory Synapse Development on Dentate Gyrus Granule Cells
Siddiqui, T. J., Tari, P. K., Connor, S. A., Zhang, P., Dobie, F. A., She, K., Kawabe, H., Wang, Y. T., Brose, N., & Craig, A. M. (2013) · Neuron · doi:10.1016/j.neuron.2013.06.029 · Cited by 186
Thrombospondins as key regulators of synaptogenesis in the central nervous system
Risher, W. C., & Eroğlu, Ç. (2012) · Matrix Biology · doi:10.1016/j.matbio.2012.01.004 · Cited by 186
Astrocytes refine cortical connectivity at dendritic spines
Risher, W. C., Patel, S. S., Kim, I. H., Uezu, A., Bhagat, S., Wilton, D. K., Pilaz, L., Alvarado, J. S., Calhan, O. Y., Silver, D. L., et al. (2014) · eLife · doi:10.7554/elife.04047 · Cited by 184
Cell Surface Expression of Polysialic Acid on NCAM Is a Prerequisite for Activity-Dependent Morphological Neuronal and Glial Plasticity
Theodosis, D. T., Bonhomme, R., Vitiello, S., Rougon, G. N., & Poulain, D. A. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-23-10228.1999 · Cited by 183
SynCAM 1 Adhesion Dynamically Regulates Synapse Number and Impacts Plasticity and Learning
Robbins, E. M., Krupp, A. J., de Arce, K. P., Ghosh, A. K., Fogel, A. I., Boucard, A. A., Südhof, T. C., Stein, V., & Biederer, T. (2010) · Neuron · doi:10.1016/j.neuron.2010.11.003 · Cited by 183
Astrocytes Regulate Inhibitory Synapse Formation via Trk-Mediated Modulation of Postsynaptic GABAAReceptors
Elmariah, S. B., Oh, E. J., Hughes, E. G., & Balice‐Gordon, R. J. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.3980-04.2005 · Cited by 182
Extracellular matrix abnormalities in schizophrenia
Berretta, S. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.08.010 · Cited by 179
The axonal recognition molecule F11 is a multifunctional protein: Specific domains mediate interactions with Ng-CAM and restrictin
Brm̈mendorf, T., Hubert, M. J., Treubert, U., Leuschner, R., Tárnok, A., & Rathjen, F. G. (1993) · Neuron · doi:10.1016/0896-6273(93)90172-n · Cited by 179
Neuronal Pentraxins Mediate Synaptic Refinement in the Developing Visual System
Bjartmar, L., Huberman, A. D., Ullian, E. M., Renteria, R. C., Liu, X., Xu, W., Prezioso, J., Susman, M. W., Stellwagen, D., Stokes, C. C., et al. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.4212-05.2006 · Cited by 179
Synaptic proteins and receptors defects in autism spectrum disorders
Chen, J., Yu, S., Fu, Y., & Li, X. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00276 · Cited by 178
Syndecans as cell surface receptors: Unique structure equates with functional diversity
Choi, Y., Chung, H., Jung, H., Couchman, J., & Oh, E. (2010) · Matrix Biology · doi:10.1016/j.matbio.2010.10.006 · Cited by 175
Astrocyte-Secreted Matricellular Proteins in CNS Remodelling during Development and Disease
Jones, E. V., & Bouvier, D. S. (2014) · Neural Plasticity · doi:10.1155/2014/321209 · Cited by 173
A Synthetic Neural Cell Adhesion Molecule Mimetic Peptide Promotes Synaptogenesis, Enhances Presynaptic Function, and Facilitates Memory Consolidation
Cambon, K., Hansen, S. M., Venero, C., Herrero, A. I., Skibo, G. G., Berezin, V., Bock, E., & Sandi, C. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.0436-04.2004 · Cited by 172
Impairment of L-type Ca2+Channel-Dependent Forms of Hippocampal Synaptic Plasticity in Mice Deficient in the Extracellular Matrix Glycoprotein Tenascin-C
Evers, M. R., Salmen, B., Bukalo, O., Rollenhagen, A., Bösl, M. R., Morellini, F., Bartsch, U., Dityatev, A., & Schachner, M. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-16-07177.2002 · Cited by 172
EphB Controls NMDA Receptor Function and Synaptic Targeting in a Subunit-Specific Manner
Nolt, M. J., Lin, Y., Hruska, M., Murphy, J. A., Sheffler-Collins, S. I., Kayser, M. S., Passer, J. Z., Bennett, M. V. L., Zukin, R. S., & Dalva, M. B. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.0282-11.2011 · Cited by 169
Identification of integrin α3β1 as a neuronal thrombospondin receptor mediating neurite outgrowth
DeFreitas, M. F., Yoshida, C. K., Frazier, W. A., Mendrick, D. L., Kypta, R. M., & Reichard, L. F. (1995) · Neuron · doi:10.1016/0896-6273(95)90038-1 · Cited by 169
AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats
Kuja‐Panula, J., Kiiltomäki, M., Yamashiro, T., Rouhiainen, A., & Rauvala, H. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200209074 · Cited by 167
Unbiased Discovery of Glypican as a Receptor for LRRTM4 in Regulating Excitatory Synapse Development
de Wit, J., O’Sullivan, M. L., Savas, J. N., Condomitti, G., Caccese, M., Vennekens, K. M., Yates, J. R., & Ghosh, A. (2013) · Neuron · doi:10.1016/j.neuron.2013.06.049 · Cited by 166
Syndecan-3-Deficient Mice Exhibit Enhanced LTP and Impaired Hippocampus-Dependent Memory
Kaksonen, M., Pavlov, I., Võikar, V., Lauri, S. E., Hienola, A., Riekki, R., Lakso, M., Taira, T., & Rauvala, H. (2002) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.2002.1167 · Cited by 162
Integrin-Mediated Transforming Growth Factor-β Activation, a Potential Therapeutic Target in Fibrogenic Disorders
Nishimura, S. L. (2009) · American Journal Of Pathology · doi:10.2353/ajpath.2009.090393 · Cited by 162
Inhibition of cytokine-induced connexin43 hemichannel activity in astrocytes is neuroprotective
Froger, N., Orellana, J. A., Calvo, C., Amigou, E., Kozoriz, M. G., Naus, C. C. G., Sáez, J. C., & Giaume, C. (2010) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2010.05.007 · Cited by 162
α9 Integrin Promotes Neurite Outgrowth on Tenascin-C and Enhances Sensory Axon Regeneration
Andrews, M. R., Czvitkovich, S., Dassie, E., Vogelaar, C. F., Faissner, A., Blits, B., Gage, F. H., ffrench‐Constant, C., & Fawcett, J. W. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.0759-09.2009 · Cited by 161
Morphological plasticity of astroglia: Understanding synaptic microenvironment
Heller, J. P., & Rusakov, D. A. (2015) · Glia · doi:10.1002/glia.22821 · Cited by 160
Characterization of the Promoter for the Human Long Pentraxin PTX3
Basile, A., Sica, A., d’Aniello, E., Breviario, F., Garrido, G., Castellano, M., Mantovani, A., & Introna, M. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.13.8172 · Cited by 159
Expression of astrocytic markers aquaporin 4 and connexin 43 is altered in brains of subjects with autism
Fatemi, S. H., Folsom, T. D., Reutiman, T. J., & Lee, S. S. (2008) · Synapse · doi:10.1002/syn.20519 · Cited by 157
δ-Protocadherins: unique structures and functions
Redies, C., Vanhalst, K., & Roy, F. M. V. (2005) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-005-5320-z · Cited by 157
Coregulation of Fibronectin Signaling and Matrix Contraction by Tenascin-C and Syndecan-4
Midwood, K. S., Valenick, L. V., Hsia, H. C., & Schwarzbauer, J. E. (2004) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-08-0759 · Cited by 157
Arcadlin Is a Neural Activity-regulated Cadherin Involved in Long Term Potentiation
Yamagata, K., Andreasson, K. I., Sugiura, H., Maru, E., Müller, D., Irie, Y., Miki, N., Hayashi, Y., Yoshioka, M., Kaneko, K., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.27.19473 · Cited by 157
γ-Protocadherins Are Targeted to Subsets of Synapses and Intracellular Organelles in Neurons
Phillips, G. R., Tanaka, H., Frank, M., Elste, A. M., Fidler, L., Benson, D. L., & Colman, D. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-12-05096.2003 · Cited by 154
Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis
Stenzel, D., Lundkvist, A., Sauvaget, D., Busse, M., Graupera, M., van der Flier, A., Wijelath, E. S., Murray, J., Sobel, M., Costell, M., et al. (2011) · Development · doi:10.1242/dev.071381 · Cited by 154
A novel gene family encoding leucine-rich repeat transmembrane proteins differentially expressed in the nervous system☆☆Sequence data from this article have been deposited with the DDBJ/EMBL/GenBank Data Libraries under Accession Nos. AY182024 (human LRRTM1), AY182026 (human LRRTM2), AY182028 (human LRRTM3), AY182030 (human LRRTM4), AY182025 (mouse LRRTM1), AY182027 (mouse LRRTM2), AY182029 (mouse LRRTM3), and AY182031 (mouse LRRTM4).
Laurén, J., Airaksinen, M. S., Saarma, M., & Timmusk, T. (2003) · Genomics · doi:10.1016/s0888-7543(03)00030-2 · Cited by 151
Biochemical Interactions of the Neuronal Pentraxins
Kirkpatrick, L., Matzuk, M. M., Dodds, D. C., & Perin, M. S. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m002254200 · Cited by 149
Calcium-dependent N-cadherin up-regulation mediates reactive astrogliosis and neuroprotection after brain injury
Kanemaru, K., Kubota, J., Sekiya, H., Hirose, K., Okubo, Y., & Iino, M. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1300378110 · Cited by 147
Silencing of Neuroligin Function by Postsynaptic Neurexins
Taniguchi, H., Gollan, L., Scholl, F. G., Mahadomrongkul, V., Dobler, E., Limthong, N., Peck, M., Aoki, C. J., & Scheiffele, P. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0032-07.2007 · Cited by 147
Syndecan-2 induces filopodia and dendritic spine formation via the neurofibromin–PKA–Ena/VASP pathway
Lin, Y., Lei, Y.-T., Hong, C., & Hsueh, Y. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200608121 · Cited by 147
Presynaptic neuronal pentraxin receptor organizes excitatory and inhibitory synapses
Lee, S.-J., Wei, M., Zhang, C., Maxeiner, S., Pak, C., Calado Botelho, S., Trotter, J., Sterky, F. H., & Südhof, T. C. (2017) · The Journal of Neuroscience · doi:10.1523/jneurosci.2768-16.2016 · Cited by 146
Astrocytes Control Glutamate Receptor Levels at Developing Synapses through SPARC–β-Integrin Interactions
Jones, E. V., Bernardinelli, Y., Tse, Y. C., Chierzi, S., Wong, T. P., & Murai, K. K. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.4757-10.2011 · Cited by 145
The role of neural cell adhesion molecules in plasticity and repair
Kiss, J. Z., Troncoso, E., Djebbara‐Hannas, Z., Vutskits, L., & Müller, D. (2001) · Brain Research Reviews · doi:10.1016/s0165-0173(01)00093-5 · Cited by 145
Synaptic laminin prevents glial entry into the synaptic cleft
Patton, B. L., Chiu, A. Y., & Sanes, J. R. (1998) · Nature · doi:10.1038/31502 · Cited by 143
Neuronal pentraxin receptor in cerebrospinal fluid as a potential biomarker for neurodegenerative diseases
Yin, G. N., Lee, H. W., Cho, J.-Y., & Suk, K. (2009) · Brain Research · doi:10.1016/j.brainres.2009.01.058 · Cited by 143
Primary Hippocampal Neurons, Which Lack Four Crucial Extracellular Matrix Molecules, Display Abnormalities of Synaptic Structure and Function and Severe Deficits in Perineuronal Net Formation
Geissler, M., Gottschling, C., Aguado, A., Rauch, U., Wetzel, C. H., Hatt, H., & Faissner, A. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.3275-12.2013 · Cited by 140
Expression of the Astrocyte Water Channel Aquaporin-4 in the Mouse Brain
Hubbard, J. A., Hsu, M. S., Seldin, M. M., & Binder, D. K. (2015) · ASN NEURO · doi:10.1177/1759091415605486 · Cited by 140
Glial–Gonadotrophin Hormone (GnRH) Neurone Interactions in the Median Eminence and the Control of GnRH Secretion
Ojeda, S., Lomniczi, A., & Sandau, U. (2008) · Journal of neuroendocrinology · doi:10.1111/j.1365-2826.2008.01712.x · Cited by 139
Deconstructing the perineuronal net: Cellular contributions and molecular composition of the neuronal extracellular matrix
Giamanco, K. A., & Matthews, R. T. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.05.055 · Cited by 138
Control of extracellular matrix assembly by syndecan-2 proteoglycan
Klass, C. M., Couchman, J., & Woods, A. (2000) · Journal of Cell Science · doi:10.1242/jcs.113.3.493 · Cited by 137
Extracellular matrix protein expression is brain region dependent
Dauth, S., Grevesse, T., Pantazopoulos, H., Campbell, P. H., Maoz, B. M., Berretta, S., & Parker, K. K. (2016) · The Journal of Comparative Neurology · doi:10.1002/cne.23965 · Cited by 137
Cadherin-13, a risk gene for ADHD and comorbid disorders, impacts GABAergic function in hippocampus and cognition
Rivero, O., Selten, M. M., Sich, S., Popp, S., Bacmeister, L., Amendola, E., Negwer, M., Schubert, D., Proft, F., Kiser, D. P., et al. (2015) · Translational Psychiatry · doi:10.1038/tp.2015.152 · Cited by 135
Nectin-like molecule-1/TSLL1/SynCAM3: a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule localizing at non-junctional contact sites of presynaptic nerve terminals, axons and glia cell processes
Kakunaga, S., Ikeda, W., Itoh, S., Deguchi‐Tawarada, M., Ohtsuka, T., Mizoguchi, A., & Takai, Y. (2005) · Journal of Cell Science · doi:10.1242/jcs.01656 · Cited by 134
Chondroitin sulfate proteoglycans regulate astrocyte‐dependent synaptogenesis and modulate synaptic activity in primary embryonic hippocampal neurons
Pyka, M., Wetzel, C., Aguado, A., Geissler, M., Hatt, H., & Faissner, A. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07690.x · Cited by 131
Neurons control the expression of connexin 30 and connexin 43 in mouse cortical astrocytes
Koulakoff, A., Ezan, P., & Giaume, C. (2008) · Glia · doi:10.1002/glia.20698 · Cited by 130
Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction
Nishimune, H., Valdez, G., Jarad, G., Moulson, C. L., Müller, U., Miner, J., & Sanes, J. (2008) · Journal of Cell Biology · doi:10.1083/jcb.200805095 · Cited by 125
Cell adhesion molecules in the central nervous system
Togashi, H., Sakisaka, T., & Takai, Y. (2009) · Cell Adhesion & Migration · doi:10.4161/cam.3.1.6773 · Cited by 124
Versican V2 Assembles the Extracellular Matrix Surrounding the Nodes of Ranvier in the CNS
Dours-Zimmermann, M. T., Maurer, K., Rauch, U., Stoffel, W., Fassler, R., & Zimmermann, D. R. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4158-08.2009 · Cited by 123
Transmembrane domains of the syndecan family of growth factor coreceptors display a hierarchy of homotypic and heterotypic interactions
Dews, I. C., & MacKenzie, K. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0708909105 · Cited by 122
Integrin signaling cascades are operational in adult hippocampal synapses and modulate NMDA receptor physiology
Bernard‐Trifilo, J. A., Kramár, E. A., Torp, R., Lin, C., Pineda, E. A., LYNCH, G. S., & Gall, C. M. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03062.x · Cited by 120
Integrins in the development function and dysfunction of the nervous system
Clegg, D. (2003) · Frontiers in bioscience · doi:10.2741/1020 · Cited by 119
31 control of extracellular matrix assembly by syndecan-2 proteoglycan
Couchman, Klass, & Woods, A. (1999) · PubMed · Cited by 119
Tenascin-C Promotes Neurite Outgrowth of Embryonic Hippocampal Neurons through the Alternatively Spliced Fibronectin Type III BD Domains via Activation of the Cell Adhesion Molecule F3/Contactin
Rigato, F., Garwood, J., Calco, V., Heck, N., Faivre‐Sarrailh, C., & Faissner, A. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-15-06596.2002 · Cited by 118
Translational potential of astrocytes in brain disorders
Verkhratsky, A., Steardo, L., Parpura, V., & Montana, V. (2015) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.09.003 · Cited by 115
Astrocytes and Synaptic Plasticity
Barker, A. J., & Ullian, E. M. (2010) · The Neuroscientist · doi:10.1177/1073858409339215 · Cited by 115
Postsynaptic N -methyl- d -aspartate receptor function requires α-neurexins
Kattenstroth, G., Tantalaki, E., Südhof, T. C., Gottmann, K., & Missler, M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308626100 · Cited by 112
PTPσ functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission
Ko, J. S., Pramanik, G., Um, J. W., Shim, J. S., Lee, D., Kim, K. H., Chung, G.-Y., Condomitti, G., Kim, H. M., Kim, H., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1410138112 · Cited by 107
Astroglial networks promote neuronal coordination
Chever, O., Dossi, E., Pannasch, U., Derangeon, M., & Rouach, N. (2016) · Science Signaling · doi:10.1126/scisignal.aad3066 · Cited by 107
Contactins in the neurobiology of autism
Zuko, A., Kleijer, K. T. E., Oguro‐Ando, A., Kas, M. J., van Daalen, E., van der Zwaag, B., & Burbach, J. P. H. (2013) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2013.07.016 · Cited by 107
Self-citation
BDNF regulation under GFAP promoter provides engineered astrocytes as a new approach for long-term protection in Huntington's disease
Giralt, A., Friedman, H. C., Caneda-Ferrón, B., Urbán, N., Moreno, E., Rubio, N., Blanco, J., Peterson, A. C., Canals, J. M., & Alberch, J. (2010) · Gene Therapy · doi:10.1038/gt.2010.71 · Cited by 106
Identification of Astrocyte Secreted Proteins with a Combination of Shotgun Proteomics and Bioinformatics
Dowell, J. A., Johnson, J. A., & Li, L. (2009) · Journal of Proteome Research · doi:10.1021/pr900248y · Cited by 106
Physiological and pathophysiological outcomes of the interactions of HMGB1 with cell surface receptors
Rauvala, H., & Rouhiainen, A. (2009) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2009.11.012 · Cited by 106
Neuronal, glial and synaptic remodeling in the adult hypothalamus: functional consequences and role of cell surface and extracellular matrix adhesion molecules
Theodosis, D. T., Piet, R., Poulain, D. A., & Oliet, S. H. R. (2004) · Neurochemistry International · doi:10.1016/j.neuint.2003.11.003 · Cited by 105
Brevican distinctively assembles extracellular components at the large diameter nodes of Ranvier in the CNS
Bekku, Y., Rauch, U., Ninomiya, Y., & Oohashi, T. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.05873.x · Cited by 104
The chondroitin sulphate proteoglycan brevican is upregulated by astrocytes after entorhinal cortex lesions in adult rats
Thon, N., Haas, C. A., Rauch, U., Merten, T., Fässler, R., Frotscher, M., & Deller, T. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00109.x · Cited by 104
Neuritogenesis Induced by Thyroid Hormone-treated Astrocytes Is Mediated by Epidermal Growth Factor/Mitogen-activated Protein Kinase-Phosphatidylinositol 3-Kinase Pathways and Involves Modulation of Extracellular Matrix Proteins
Martinez, R., & Gomes, F. C. A. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m209284200 · Cited by 103
The Na-K-ATPase α 1 β 1 heterodimer as a cell adhesion molecule in epithelia
Vagin, O., Dada, L. A., Tokhtaeva, E., et al. (2012) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00456.2011 · Cited by 103
Structural Characterization of the EphA4-Ephrin-B2 Complex Reveals New Features Enabling Eph-Ephrin Binding Promiscuity
Qin, H., Noberini, R., Huan, X., Shi, J., Pasquale, E. B., & Song, J. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.064824 · Cited by 101
Defining cell populations with single-cell gene expression profiling: correlations and identification of astrocyte subpopulations
Ståhlberg, A., Andersson, D., Aurelius, J., Faiz, M., Pekna, M., Kubista, M., & Pekny, M. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq1182 · Cited by 101

Research works printed but not linked: 1

Lauren, 2003, A novel gene family encoding leucine-rich repeat transmembrane proteins differentially expressed in the nervous system, Genomics, 81, 411

Sorted by citations

Single-nucleus transcriptome analysis reveals dysregulation of angiogenic endothelial cells and neuroprotective glia in Alzheimer’s disease
Lau, S.-F., Cao, H., Fu, A. K. Y., & Ip, N. Y. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2008762117 · Cited by 476
Linking inflammation, aberrant glutamate-dopamine interaction, and post-synaptic changes: translational relevance for schizophrenia and antipsychotic treatment: a systematic review
de Bartolomeis, A., Barone, A., Vellucci, L., Mazza, B., Austin, M. C., Iasevoli, F., & Ciccarelli, M. (2022) · Molecular Neurobiology · doi:10.1007/s12035-022-02976-3 · Cited by 113

See all 108

Authors: Hillen, A. E. J., Burbach, J. P. H., & Hol, E. M.
Affiliations: University Medical Center Utrecht (NL)
Netherlands Institute for Neuroscience (NL)
Corresponding author: Hol, Elly M.
ORCID: Hillen, Anne E.J.
Burbach, J. Peter H.
Hol, Elly M.
Venue: Progress in Neurobiology
Publisher: Elsevier BV
Published: 2018-06
Volume: 165-167
Pages: 66-86
ISSN: 0301-0082 (ISSN-L)
DOI: 10.1016/j.pneurobio.2018.02.002
OpenAlex: W2790000715
Cited by: 108
References: 375
Citations by year: 2026: 7 · 2025: 16 · 2024: 11 · 2023: 17 · 2022: 14 · 2021: 13 · 2020: 19 · 2019: 6 · 2018: 5
FWCI: 1.39
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-nd
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
creativecommons.org/licenses/by-nc-nd/4.0/ (vor, 36 d)
Locations: Progress in Neurobiology (publishedVersion, cc-by-nc-nd)
PubMed (publishedVersion)
Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion, other-oa)
KNAW research portal (Royal Academy of Art and Sciences (KNAW)) (publishedVersion, other-oa)
Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
Utrecht University Repository (Utrecht University) (submittedVersion, other-oa)
Pure Amsterdam UMC (submittedVersion, other-oa)
KNAW Research Portal (The Royal Netherlands Academy of Arts and Sciences) (submittedVersion, other-oa)
Funders: Autism Speaks (115300)
European Federation of Pharmaceutical Industries and Associations
European Commission (2007–2013, 115300)
Hersenstichting
Internationale Stichting Alzheimer Onderzoek (08504, 12509)
Innovative Medicines Initiative (115300)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Connexins and lens biology
Keywords: astrocytes, tripartite synapse, adhesion molecules, matricellular proteins, astrocyte-neuron interaction, synaptogenesis, synaptic plasticity, astrocyte dysfunction, autism spectrum disorder, schizophrenia
MeSH terms: Animals, Astrocytes, Extracellular Matrix, Humans, Membrane Proteins, Synaptic Transmission, Neurons, Synapses, Cell Adhesion Molecules

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Cell adhesion and matricellular support by astrocytes of the tripartite synapse

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks