Asperger syndrome in adolescent and young adult males. Interview, self - and parent assessment of social, emotional, and cognitive problems
Abstract
Descriptive and comparative follow-up studies of young adult males with Asperger syndrome (AS) diagnosed in childhood, using both interview, self- and parent assessment instruments for the study of aspects of emotional well-being, social functioning, and cognitive-practical skills have not been performed in the past. One-hundred males with AS diagnosed in childhood were approached for the assessment using the Asperger Syndrome Diagnostic Interview (ASDI), (personal and parent interview), the Leiter-R-Questionnaires, the Beck Depression Inventory (BDI), and the Dysexecutive Questionnaire (DEX). About 75% of the targeted group participated. The ASDI results came out significantly different at personal vs parent interviews in several key domains. In contrast, the Leiter-R-Questionnaires, showed no significant differences across the individuals with AS and their parents in the scoring of cognitive/social and emotional/adaptive skills. The BDI proved to be an adequate screening instrument for depression in that it correctly identified the vast majority of cases with clinical depression in the AS group. The DEX results suggested an executive function deficit problem profile in males with AS as severe as that reported in groups of individuals with traumatic brain injury and schizophrenia. Interviews (personal and collateral), and self-rating and parent-rating questionnaires all have a role in the comprehensive diagnostic process in AS and other autism spectrum disorders, and could be used as adjuncts when evaluating whether or not individuals meeting diagnostic symptom criteria for the condition have sufficient problems in daily life to warrant a clinical diagnosis of AS.
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Two studies have reported that the BDI-II presents as an adequate screening tool for depression in autism, with good internal consistency, adequate sensitivity and specificity, and good convergent validity.
“Two studies 23,24 have investigated the usefulness of the Beck Depression Inventory, version 2 (BDI-II), 25 in autism, reporting that it presents as an adequate screening tool for depression, 23 with good internal consistency, adequate sensitivity and specificity, and good convergent validity. 24”
From Guided self-help for depression in autistic adults: The ADEPT feasibility RCT (2019) · cites this paper as [23]
A number of explanations for the high comorbidity rates have been suggested, including shared genetic etiology, self-medication of symptoms, and common socioenvironmental determinants.
“A number of explanations for the high comorbidity rates have been suggested, including shared genetic etiology, self-medication of symptoms, and common socioenvironmental determinants [752,753]”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [752]
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- Authors
- Cederlund, M., Hagberg, B., & Gillberg, C.
- Affiliations
- University of Gothenburg (SE)
- Corresponding author
- Gillberg, Christopher
- Venue
- Research in Developmental Disabilities
- Publisher
- Elsevier BV
- Published
- 2010-03
- Volume
- 31
- Issue
- 2
- Pages
- 287-298
- ISSN
- 0891-4222 (ISSN-L)
- OpenAlex
- W2032715369
- Cited by
- 145
- References
- 40
- Citations by year
- 2026: 4 · 2025: 8 · 2024: 2 · 2022: 6 · 2021: 6 · 2020: 8 · 2019: 8 · 2018: 8 · 2017: 8 · 2016: 6 · 2015: 9 · 2014: 12 · 2013: 18 · 2012: 13
- FWCI
- 6.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Research in Developmental Disabilities (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Social Sciences › Psychology › Clinical Psychology › Family and Disability Support Research
- Keywords
- Asperger syndrome, adolescent and young adult males, social functioning, emotional well-being, executive dysfunction, depression screening, self-report measures, autism spectrum disorder, follow-up study
- MeSH terms
- Adolescent, Cognition Disorders, Emotions, Humans, Interviews as Topic, Male, Parents, Surveys and Questionnaires, Social Adjustment, Asperger Syndrome, Young Adult, Executive Function
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