A systematic review of the rates of depression in children and adults with high functioning autism spectrum disorder
Open accessAbstract
Accurate population rates of depression can inform allocation of health resources and service planning, to counter the impact of depression on quality of life and morbidity. A systematic review of the rates of depression in children and adults with autism spectrum disorders (ASD) and without intellectual disability (high-functioning [HF] ASD) was conducted. Nineteen studies met inclusion criteria. Reported rates of depression varied; the reasons for this are discussed including availability of psychometrically valid and reliable measures of depression for people with HF ASD, and heterogeneity of study design. Further examination of the phenomenology of depression in HF ASD linked to the development of psychometrically valid assessment measures would facilitate epidemiological studies, improve clinical case recognition, and inform treatments and interventions.
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Rates of depression in autism range from 4% to 35% across the lifespan.
“rates of depression ranging from 4% to 35% across the lifespan. 9”
From Guided self-help for depression in autistic adults: The ADEPT feasibility RCT (2019) · cites this paper as [9]
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- Authors
- Wigham, S., Barton, S., Parr, J. R., & Rodgers, J.
- Affiliations
- Newcastle University (GB)
- Cumbria Northumberland Tyne and Wear NHS Foundation Trust (GB)
- Corresponding author
- Wigham, Sarah
- Venue
- Journal of Mental Health Research in Intellectual Disabilities
- Publisher
- Informa UK Limited
- Published
- 2017-03-22
- Volume
- 10
- Issue
- 4
- Pages
- 267-287
- ISSN
- 1931-5864 (ISSN-L)
- 1931-5872
- OpenAlex
- W2600105590
- Cited by
- 107
- References
- 68
- Citations by year
- 2026: 5 · 2025: 4 · 2024: 12 · 2023: 13 · 2022: 13 · 2021: 15 · 2020: 15 · 2019: 13 · 2018: 12 · 2017: 5
- FWCI
- 1.38
- Type
- journal article
- Language
- en
- Open access
- green
- doi.org
- Licence
- cc-by-nc-nd
- Locations
- Journal of Mental Health Research in Intellectual Disabilities (publishedVersion)
- Newcastle University ePrints (Newcastle Univesity) (cc-by-nc-nd)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Keywords
- depression, high-functioning autism, prevalence rates, children, adults, psychometric validity, epidemiology of depression, quality of life
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