Aerobic exercise improves self-reported sleep and quality of life in older adults with insomnia
Open accessAbstract
Objective To assess the efficacy of moderate aerobic physical activity with sleep hygiene education to improve sleep, mood and quality of life in older adults with chronic insomnia.Methods Seventeen sedentary adults aged >or=55 years with insomnia (mean age 61.6 [SD±4.3] years; 16 female) participated in a randomized controlled trial comparing 16 weeks of aerobic physical activity plus sleep hygiene to non-physical activity plus sleep hygiene. Eligibility included primary insomnia for at least 3 months, habitual sleep duration <6.5h and a Pittsburgh Sleep Quality Index (PSQI) score >5. Outcomes included sleep quality, mood and quality of life questionnaires (PSQI, Epworth Sleepiness Scale [ESS], Short-form 36 [SF-36], Center for Epidemiological Studies Depression Scale [CES-D]).Results The physical activity group improved in sleep quality on the global PSQI (p<.0001), sleep latency (p=.049), sleep duration (p=.04), daytime dysfunction (p=.027), and sleep efficiency (p=.036) PSQI sub-scores compared to the control group. The physical activity group also had reductions in depressive symptoms (p=.044), daytime sleepiness (p=.02) and improvements in vitality (p=.017) compared to baseline scores.Conclusion Aerobic physical activity with sleep hygiene education is an effective treatment approach to improve sleep quality, mood and quality of life in older adults with chronic insomnia.
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- Findingown data
There was a significant time by condition interaction for the PSQI sleep onset latency sub-score.
“a significant time by condition interaction for sleep onset latency (F(1,15)=5.39, p= .035)”
Quote in the paperSubstantial claim - Findingown data
A reduction in global PSQI scores was associated with a greater reduction in depressive symptoms on the CES-D.
“A reduction in global PSQI scores was also associated with a greater reduction in depressive symptoms on the CES-D (r=0.487, p=0.048).”
Quote in the paperNot a substantial claim - Findingown data
There were trends for time by condition effects in the SF-36 role emotional and mental health domains.
“a trend for time by condition effects in role emotional (F (1,15)= 4.214, p= .058) and mental health (F (1,15) 3.44, p = .08).”
Quote in the paperNot a substantial claim - Findingown data
There were no significant time or time by condition effects for the SF-36 role physical, general health, or social functioning domains.
“There were no significant time or time by condition effects for role physical, general health, or social functioning.”
Quote in the paperNot a substantial claim - Findingown data
Reductions in global PSQI scores were not associated with improvements in maximum heart rate or VO2max.
“Reductions in global PSQI scores were not associated with greater improvements in maximum heart rate or VO2max.”
Quote in the paperNot a substantial claim
- Findingown data
After controlling for depression, there remained a significant relationship between physical activity group and change in PSQI scores.
“After controlling for depression, there continued to be a significant relationship between physical activity group and change in PSQI scores (B= 5.003, p=0.002).”
Quote in the paperSubstantial claim - Findingown data
The change in global PSQI was not related to change in daytime sleepiness measured by the ESS.
“The change in global PSQI was not related to change in daytime sleepiness measured by the ESS.”
Quote in the paperNot a substantial claim - Findingown data
There was a significant effect for time on the PSQI subjective sleep quality sub-score.
“there was a significant effect for time on subjective sleep quality (F(1,15)= 26.09, p< .001)”
Quote in the paperSubstantial claim - Findingown data
There was a significant time by group interaction for global PSQI scores, with the interaction and error accounting for 57.7% of the variance in PSQI change.
“There was a significant effect for time (F (1,15)= 9.96, p=.007), as well as a time by group interaction for global PSQI scores (F (1,15)= 20.49, p<. 001; Figure 1a). The time by condition interaction plus the error for this effect accounted for 57.7% of the variance on change in PSQI scores (partial η2 = .577).”
Quote in the paperSubstantial claim - Findingown data
There was a significant time by condition interaction for the PSQI sleep efficiency sub-score.
“There was also a significant time by condition interaction for sleep latency (F (1,15) = 5.39, p= .04) and sleep efficiency (F (1,15)= p= .036).”
Quote in the paperSubstantial claim - Findingown data
There was a significant time by condition effect for the SF-36 vitality domain.
“There was a significant time by condition effect for vitality (F (1,15)= 7.207, p= .017)”
Quote in the paperSubstantial claim - Findingown data
There was no similar correlation between sleep quality and V02 max.
“However, a similar correlation between sleep quality and V02 max was not seen.”
Quote in the paperSubstantial claim - Findingown data
The exercise group's SF-36 vitality score improved by 25.5 points, compared with a 0.12 point reduction in the non-physical activity group.
“For the exercise group the vitality measure from the SF-36 improved substantially by 25.5 points following intervention compared to a 0.12 reduction for the non-physical activity group.”
Quote in the paperSubstantial claim - Findingown data
In the exercise group, there was a trend for a positive relationship between improvements in sleep quality and improvements in maximum heart rate.
“There was a positive relationship between improvements in sleep quality and improvements in fitness level as determined by maximum heart rate in the exercise group, although this was only a trend (p=0.058).”
Quote in the paperNot a substantial claim - Findingown data
In the whole group, there was a significant association between improvements in depressive symptoms and improvements in subjective sleep quality.
“in our study, there was a significant association between improvements in depressive symptoms and improvements in subjective sleep quality in the whole group.”
Quote in the paperNot a substantial claim - Interpretationreasoning
The large increase in sleep duration may be partly due to the inclusion criterion of habitual sleep duration less than 6.5 hours per night.
“This large increase in sleep duration may be in part due to the inclusion criteria of having a habitual sleep duration of less than 6.5 hours a night, which was verified with wrist actigraphy and sleep log.”
Quote in the paperNot a substantial claim - Study design and conductown data
At baseline, there were no significant differences in any sleep parameters between the two groups.
“There were no significant differences in any of the sleep parameters between the two groups.”
Quote in the paperSubstantial claim - Premisecitation
A study of the hypnotic eszopiclone over 1-6 months reported a 15 point increase in vitality.
“In comparison with pharmacological therapies, in a study of the hypnotic eszopiclone over a 1-6 month period there was a 15 point increase in vitality [45].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [45] source
Not checked in the free run.
- Interpretationcitation
The difference between the PSQI sleep latency sub-score and continuous sleep latency may be because the sub-score reflects both sleep latency and the frequency of being unable to fall asleep within 30 minutes.
“This apparent difference could be because the PSQI sleep latency sub-score reflects both sleep latency and the frequency of being unable to fall asleep within 30 minutes [31].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [31] source
Not checked in the free run.
- Interpretationown data
The effect of exercise on sleep quality, mood, and sleepiness may be mediated by mechanisms other than cardiopulmonary fitness alone.
“These results suggest that the effect of exercise on sleep quality, mood and sleepiness may be mediated via mechanism other than only cardiopulmonary fitness.”
Quote in the paperSubstantial claim - Interpretationcitation
The change in vitality in the current study was greater than the differences reported between people with insomnia and controls (16 points) or patients with depression and controls (13 points).
“Furthermore, the degree of change in vitality in the current study was greater than the differences seen between people with insomnia and controls (16 points) or patients with depression and controls (13 points) [44].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [44]
Not checked in the free run.
- Classified as probably not a substantial claim. 11
- May combine two claims. 25
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingown dataThere was a trend toward an effect for time on maximum heart rate, but no time by condition effect.
“There was a trend toward an effect for time on maximum heart rate (F (1,15)= 3.51, p= .08) but no time by condition effect.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThere was no significant time or time by condition effect for sleep latency measured as a continuous variable.
“There was not a significant time or time by condition effect for sleep latency measured as a continuous variable.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThe current study achieved an average 4.8 point reduction in PSQI score, compared with a 1.8 point decrease reported in a 25-week Tai Chi study.
“Compared to a 25 week Tai Chi study that reported a significant decrease in PSQI score of 1.8 points [39], the current study achieved an average 4.8 point reduction in PSQI score.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [39]
Not checked in the free run.
May combine two claims.
Findingown dataThere was an effect for time on SF-36 vitality and a trend toward improvement over time in physical function.
“There was an effect for time on vitality (F(1,15), 7.207, p= .02) and a trend toward improvement over time in physical function (F (1,15)= 4.309, p=.056).”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingown dataThe exercise group showed a trend toward improvement in V02max, while the non-physical activity group did not.
“Pre-post comparisons for each group demonstrated a trend toward improvements in V02max for the exercise group (t(9) -1.93, p= .08) but not for the non-physical activity group.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataIn older adults with chronic insomnia, the exercise group showed a significant improvement in global PSQI scores from baseline to post-treatment, while the non-physical activity group did not.
“participants in the exercise group demonstrated significant improvement in global PSQI scores (t(15)= -5.62, p< 0.0001) while participants in the non-physical activity group did not demonstrate improvement.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataThe exercise group showed significant pre-post improvements in CES-D scores, while the non-physical activity group did not.
“pre-post comparisons for each group demonstrated significant improvements in CES-D scores for the exercise group (t (9)= 2.34, p=.04) but not for the non-physical activity group.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThere were no effects of time or time by condition on V02max or maximum heart rate.
“There were no effects of time or time by condition on V02max or maximum heart rate.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThere was a significant time effect and a significant time by condition interaction for the PSQI daytime dysfunction sub-score.
“for daytime dysfunction (time F (1,15)= 12.32, p= .003, time × condition F(1,15)= 5.98, p= .03)”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataIn the exercise group alone, there was a trend for a correlation between change in maximum heart rate and PSQI scores.
“when the physical activity group was analyzed alone, there was a trend for a correlation between change in maximum HR and PSQI scores (r=0.671, p=0.058).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThere was a significant time effect and a significant time by condition interaction for the PSQI sleep duration sub-score.
“a significant time and time by condition interaction for sleep duration (time F(1,15)=4.59 p=.049, time × condition F(1,15)=4.59, p= .049)”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataWhen sleep duration was analyzed as a continuous variable, there was a significant time effect and a trend toward a time by condition interaction.
“there was a significant time effect for sleep duration and a trend toward a time by condition interaction for sleep duration (time F(1,15) = 6.44, p=.02, time by condition F(1,15) = 3.22, p=.09).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataFor the CES-D, there was no significant time or time by condition effect.
“For the CES-D, there was not a significant time or time by condition effect (Figure 1b).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThe exercise group had a significant reduction in ESS scores from baseline to post-treatment, while the non-physical activity group did not.
“there was a significant reduction in the ESS score for the exercise group (t(9)= -2.75, p=0.02) but not in the non-physical activity group”
Quote in the paperSubstantial claimMay combine two claims.
FindingcitationThe exercise plus sleep hygiene group increased self-reported sleep duration by 1.25 hours, which is higher than reported for other non-pharmacological interventions for insomnia.
“The increase in self reported sleep duration by 1.25 hours in the exercise plus sleep hygiene education group is higher than what has been reported for other non-pharmacological interventions for insomnia [30, 40]”
Quote in the paperNot a substantial claim0 of 2 sources checkedMay combine two claims.
Findingown dataFor the ESS, there was a trend for a time effect but no time by condition interaction.
“For ESS there was a trend of an effect for time (F (1, 15)= 3.18, p= .09), but there was not a time by condition interaction (F (1, 15)= 2.8, p= .12).”
Quote in the paperNot a substantial claimMay combine two claims.
FindingreasoningThere was a significant reduction in the PSQI sleep latency sub-score but not in sleep latency measured as a continuous variable.
“There was also a significant reduction in the sleep latency sub-score of the PSQI but not in sleep latency measured as a continuous variable.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
FindingcitationAt baseline, SF-36 scores in this study were similar to those previously reported for people with mild-to-severe insomnia.
“At baseline, SF-36 scores in this study were similar to those previously reported for people with mild-severe insomnia [42-44].”
Quote in the paperNot a substantial claim0 of 3 sources checked- cites [42]
Not checked in the free run.
- cites [43] source
Not checked in the free run.
- cites [44]
Not checked in the free run.
May combine two claims.
InterpretationcitationThe effect sizes for improvements in sleep duration and subjective sleep quality in this study were similar to or greater than those reported for cognitive behavioral intervention and other physical activity studies.
“The effect size for the improvements in sleep duration and subjective sleep quality in this study were similar or even greater than that reported for cognitive behavioral intervention and other physical activity studies [18, 30, 36-38].”
Quote in the paperSubstantial claim0 of 5 sources checkedProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataFive participants withdrew or were excluded after randomization; four from the non-physical activity group withdrew because they wanted the exercise condition, and one from the exercise group was withdrawn for non-compliance.
“Five participants withdrew or were excluded following randomization. The reason given for withdrawal by the four in the non-physical activity group was that they wanted to be in the exercise condition and the one participant from the activity group was withdrawn due to non-compliance.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
Study design and conductown dataParticipants were randomly assigned to either the aerobic physical activity or non-physical activity group.
“Participants were randomly assigned to either an aerobic physical activity or non-physical activity intervention group and measurements were collected at baseline and post treatment (16 weeks).”
Quote in the paperSubstantial claimMay combine two claims.
Interpretationown dataA 16-week program of moderate-intensity aerobic physical activity plus sleep hygiene education is effective in improving self-reported sleep quality, mood, and quality of life in older adults with chronic insomnia.
“Results from this study indicate that a sixteen week program of moderate intensity aerobic physical activity plus sleep hygiene education is effective in improving self reported sleep quality, mood and quality of life in older adults with chronic insomnia.”
Quote in the paperSubstantial claim- Rests on an assumption: The non-physical activity condition (recreational or educational activities) adequately controls for non-specific effects of attention, social contact, and sleep hygiene education, so that differences in outcomes can be attributed to aerobic exercise.
May combine two claims.
Interpretationown dataThe elevated baseline WASO indicates sleep maintenance insomnia, so improved sleep continuity may have contributed to the self-reported increase in sleep duration.
“In addition, the elevated baseline WASO as measured by actigraphy and PSG indicate that this group of patients had sleep maintenance insomnia type. Thus, improved sleep continuity may also have contributed to the self reported increase in sleep duration.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataThe non-physical activity group averaged 4.2 sessions per week for 139 minutes per session.
“On average participants completed 4.2 (±0.73) sessions a week for an average of 139 (±64.4) minutes each session.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataThe exercise group averaged 3.27 sessions per week for 32.3 minutes per session.
“On average participants exercised 3.27 (±0.52) times a week for an average of 32.3(±12.5) minutes each session.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataData were analyzed for 17 of the 18 participants who completed the study; one participant's data were removed because of an acute stressful event at the end of the study.
“Data were analyzed for 17 of 18 participants that completed the study. Data from one participant was removed due to an acute stressful event (de ath in the family) at the end of the study.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
Study design and conductown dataThe study was a randomized parallel pre-post trial comparing 16 weeks of aerobic physical activity plus sleep hygiene education with non-physical activity plus sleep hygiene education in sedentary adults aged 55 and older with insomnia.
“This study used a randomized parallel pre-post design. Participants were randomly assigned to either an aerobic physical activity or non-physical activity intervention group and measurements were collected at baseline and post treatment (16 weeks).”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductown dataThe study had limitations including reliance on self-reported sleep quality measures, a relatively small sample, and a female preponderance.
“There are several potential limitations in this study, including the reliance on self- reported sleep quality measures, the relatively small number of participants and the female preponderance of the sample.”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationown dataThe improvements in subjective sleep quality associated with exercise remained after adjusting for depressive symptoms, indicating that the effect of exercise on sleep quality is independent of depressive symptoms.
“However, the improvements in subjective sleep quality (PSQI score) associated with exercise remained after adjusting for depressive symptoms (CES-D score), indicating that the positive effect of exercise on sleep quality is also independent of depressive symptoms.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductreasoningThe higher dropout rate in the non-physical activity group may have affected internal validity if participants with low expectations for that intervention selectively dropped out after randomization.
“Another limitation was the higher dropout rate in the non-physical activity group. This may have been due in part to the desire of some participants to be randomized to the exercise condition. The internal validity of the study may be affected if those with low expectations for the non-physical activity intervention selectively dropped out after randomization.”
Quote in the paperNot a substantial claim
The paper relies on this without support.
Self-reported measures of overall sleep quality, sleep latency, sleep duration, alertness, and quality of life are the most widely used measures of insomnia treatment effectiveness in clinical practice.
“self-reported measures of overall sleep quality, sleep latency, sleep duration, alertness and quality of life are the most widely used measure of insomnia treatment effectiveness in clinical practice.”
The paper relies on this without support.
The non-physical activity condition (recreational or educational activities) adequately controls for non-specific effects of attention, social contact, and sleep hygiene education, so that differences in outcomes can be attributed to aerobic exercise.
“Participants in this condition selected recreational or education activities (e.g., parks and recreation, YMCA, museum lectures, church activities) which met for approximately 45 minutes, 3 to 5 times per week, for 16 weeks.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Several mechanisms provide a rationale for the improvement in insomnia symptoms from exercise, including reducing core body temperature for sleep onset, increasing melatonin and serotonin secretion, reducing depression and anxiety, and improving autonomic regulation which may reduce hyperarousal associated with insomnia.
“Several mechanisms that provide a rationale for the improvement in insomnia symptoms from exercise have been suggested [133,136,137,138,139]; these include but are not limited to reducing core body temperature for sleep onset [140,141,142,143], increasing melatonin and serotonin secretion [131,144], reducing depression and anxiety, and improving autonomic regulation which may reduce hyperarousal”
From The Cyclical Battle of Insomnia and Mental Health Impairment in Firefighters: A Narrative Review (2024) · cites this paper as [137]
The Discussion suggests that exercise’s effects on sleep may involve mechanisms beyond cardiopulmonary fitness, and the Results link improved sleep quality with reduced depressive symptoms. The paper does not identify reduced core body temperature, increased melatonin or serotonin secretion, or improved autonomic regulation as mechanisms; it also does not establish that reduced depression mediates the sleep improvement. (LLM, conf=0.84)
Experimental — accuracy not yet measuredIn a review of the literature, Kline concluded that the three studies exclusively including patients diagnosed with chronic insomnia had the most robust results regarding insomnia.
“Kline [7], in a review of the literature, concluded that the three studies that exclusively included patients diagnosed with chronic insomnia had the most robust results regarding insomnia [8–10].”
From Is sleep disturbance in patients with chronic pain affected by physical exercise or ACT-based stress management? - A randomized controlled study (2018) · cites this paper as [10]
Three of the four trials measuring adverse events found no adverse events in any participants.
“Three trials found no adverse events in any of the participants (Reid et al., 2010; Afonso et al., 2012; Chan et al., 2016).”
From Exercise can improve sleep quality: A systematic review and meta-analysis (2018) · cites this paper as Reid et al., 2010
Recent randomized controlled trials have confirmed that exercise has positive effects on sleep quality, sleep onset latency, total sleep time, sleep efficiency, and insomnia severity.
“Recent randomized controlled trials (RCTs) have confirmed that exercise has positive effects on sleep quality, sleep onset latency, total sleep time, sleep efficiency, and insomnia severity (Passos et al., 2010; Reid et al., 2010; Hartescu, Morgan & Stevinson, 2015).”
From Exercise can improve sleep quality: A systematic review and meta-analysis (2018) · cites this paper as Reid et al., 2010
Only four of the nine included trials examined adverse effects.
“First, only four of the nine included trials examined adverse effects (Reid et al., 2010; Afonso et al., 2012; Hartescu, Morgan & Stevinson, 2015).”
From Exercise can improve sleep quality: A systematic review and meta-analysis (2018) · cites this paper as Reid et al., 2010
In middle-aged adults with chronic insomnia, subjective sleep data after long-term exercise (4 weeks to 6 months) show no significant reduction in sleep onset latency or increase in total sleep time.
“No significant reduction in SOL (mean [SD], from 48.59 [21.3] min to 32.92 [14.0] min, p = 0.18) or significant increases in TST (mean [SD], from 5.33 [0.32] h to 6.0 [0.72] h, p = 0.12) was found according to subjective sleep data after long-term exercise (4 weeks – 6 months) (27,35,38).”
From Is exercise an alternative treatment for chronic insomnia? (2012) · cites this paper as [35]
Statistics recomputed
Every reported test result, recomputed from its test statistic and degrees of freedom. A result shows as not adding up only once an independent check has confirmed it.
- Not confirmedF(1, 15) = 5.39reported p = .04 · recomputed p = .035
“F (1,15) = 5.39, p = .04”
- ConsistentF(1, 15) = 9.96reported p = .007 · recomputed p = .007
“F (1,15)= 9.96, p = .007”
- Consistentt(15) = -5.62reported p < .0001 · recomputed p < .001
“t(15)= -5.62, p < .0001”
- ConsistentF(1, 15) = 26.09reported p < .001 · recomputed p < .001
“F(1,15)= 26.09, p < .001”
- ConsistentF(1, 15) = 5.39reported p = .035 · recomputed p = .035
“F(1,15)=5.39, p = .035”
- ConsistentF(1, 15) = 4.59reported p = .049 · recomputed p = .049
“F(1,15)=4.59, p = .049”
- ConsistentF(1, 15) = 12.32reported p = .003 · recomputed p = .003
“F (1,15)= 12.32, p = .003”
- ConsistentF(1, 15) = 5.98reported p = .03 · recomputed p = .027
“F(1,15)= 5.98, p = .03”
- ConsistentF(1, 15) = 6.44reported p = .02 · recomputed p = .023
“F(1,15) = 6.44, p = .02”
- ConsistentF(1, 15) = 3.22reported p = .09 · recomputed p = .093
“F(1,15) = 3.22, p = .09”
- Consistentt(9) = 2.34reported p = .04 · recomputed p = .044
“t (9)= 2.34, p = .04”
- ConsistentF(1, 15) = 4.309reported p = .056 · recomputed p = .056
“F (1,15)= 4.309, p = .056”
- ConsistentF(1, 15) = 7.207reported p = .017 · recomputed p = .017
“F (1,15)= 7.207, p = .017”
- ConsistentF(1, 15) = 4.214reported p = .058 · recomputed p = .058
“F (1,15)= 4.214, p = .058”
- ConsistentF(1, 15) = 3.18reported p = .09 · recomputed p = .095
“F (1, 15)= 3.18, p = .09”
- ConsistentF(1, 15) = 2.8reported p = .12 · recomputed p = .115
“F (1, 15)= 2.8, p = .12”
- Consistentt(9) = -2.75reported p = .02 · recomputed p = .022
“t(9)= -2.75, p = .02”
- ConsistentF(1, 15) = 3.51reported p = .08 · recomputed p = .081
“F (1,15)= 3.51, p = .08”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Exercise-group t test degrees of freedom imply 16 subjects, not 10
MinorThe Results section reports an exercise-group paired t test as t(15)= -5.62, which implies 16 paired observations. But the same paper elsewhere reports the exercise-group pre-post comparison as t(9)= 2.34 / t(9)= -2.75 / t(9) -1.93, implying only 10 subjects in that group.
“In follow-up pre-post comparisons for each group, participants in the exercise group demonstrated significant improvement in global PSQI scores (t(15)= -5.62, p< 0.0001) while participants in the non-physical activity group did not demonstrate improvement.”
“However, pre-post comparisons for each group demonstrated significant improvements in CES-D scores for the exercise group (t (9)= 2.34, p=.04) but not for the non-physical activity group.”
Sleep-latency p-value differs between the abstract and results
MinorThe abstract gives p=0.049 for the sleep-latency comparison, while the results give p=.035 for the sleep-onset-latency time-by-condition interaction. These are different values for the reported between-group effect.
“sleep latency (p=0.049)”
“a significant time by condition interaction for sleep onset latency (F(1,15)=5.39, p= .035)”
Sleep-duration p-value differs between the abstract and results
MinorThe abstract reports p=0.04 for the sleep-duration comparison, but the results report p=.049 for its time-by-condition interaction. The difference is not explained by rounding to the precision shown.
“sleep duration (p=0.04)”
“time × condition F(1,15)=4.59, p= .049”
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“Although the gender imbalance may affect the generalizability of the study, our findings remain relevant to patients with insomnia because insomnia is more prevalent among women than men [48].”
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ResultAwakenings and the Return to Sleep in an Older Population
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Flagged first, then by citations
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The effects of physical activity on sleep: A meta-analytic review
Kredlow, M. A., Capozzoli, M. C., Hearon, B. A., Calkins, A. W., & Otto, M. W. (2015) · Journal of Behavioral Medicine · doi:10.1007/s10865-015-9617-6 · Cited by 1,333 · see citing works
“This may explain why our results for rapid eye movement sleep latency vary from previous metaanalyses (Youngstedt et al., 1997), which did not include more recently published RCTs.”
InfluentialExercise as a treatment for depression: A meta-analysis
Kvam, S., Kleppe, C. L., Nordhus, I. H., & Hovland, A. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.03.063 · Cited by 837 · see citing works
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Connections between sleep and cognition in older adults
Yaffe, K., Falvey, C. M., & Hoang, T. (2014) · The Lancet Neurology · doi:10.1016/s1474-4422(14)70172-3 · Cited by 796 · see citing works
Sleep and exercise: A reciprocal issue?
Chennaoui, M., Arnal, P. J., Sauvet, F., & Léger, D. (2014) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2014.06.008 · Cited by 724 · see citing works
Yang, P., Ho, K.-H., Chen, H., & Chien, M. (2012) · Journal of physiotherapy · doi:10.1016/s1836-9553(12)70106-6 · Cited by 671 · see citing works
“The data from one study (Reid et al 2010) could not be incorporated into the meta-analysis.”
BackgroundTranah, G. J., Blackwell, T., Stone, K. L., Ancoli‐Israel, S., Paudel, M. L., Ensrud, K. E., Cauley, J. A., Redline, S., Hillier, T. A., Cummings, S. R., et al. (2011) · Annals of Neurology · doi:10.1002/ana.22468 · Cited by 525 · see citing works
“Other studies have shown that physical activity also has a positive effect on circadian activity rhythms.(30,31) In addition, exposure to ambient light is known to influence cognition and affective state and bright light has phase-shifting properties that have been shown to improve cognitive performance.”
BackgroundSleep, Cognition, and Normal Aging
Scullin, M. K., & Bliwise, D. L. (2015) · Perspectives on Psychological Science · doi:10.1177/1745691614556680 · Cited by 504 · see citing works
“Importantly, even if sleep interventions ultimately have no impact on memory in older adults, improving sleep may still have several noncognitive benefits, including improved quality of life (Arakawa, Tanaka, Toguchi, Shirakawa, & Taira, 2002; Faubel et al., 2009; Reid et al., 2010), better mental health (Driscoll et…”
BackgroundCircadian rhythm as a therapeutic target
Ruan, W., Yuan, X., & Eltzschig, H. K. (2021) · Nature Reviews Drug Discovery · doi:10.1038/s41573-020-00109-w · Cited by 501 · see citing works
Sejbuk, M., Mirończuk-Chodakowska, I., & Witkowska, A. M. (2022) · Nutrients · doi:10.3390/nu14091912 · Cited by 388 · see citing works
Human needs in COVID-19 isolation
Matias, T. S., Dominski, F. H., & Marks, D. F. (2020) · Journal of Health Psychology · doi:10.1177/1359105320925149 · Cited by 367 · see citing works
“(Altena et al., 2020: 1) It has been established that physical exercise improves sleep for people of all ages (Flausino et al., 2012; Reid et al., 2010; Yang et al., 2012).”
BackgroundKline, C. E. (2014) · American Journal of Lifestyle Medicine · doi:10.1177/1559827614544437 · Cited by 364 · see citing works
The effect of the work environment on future sleep disturbances: A systematic review
Linton, S. J., Kecklund, G., Franklin, K. A., Leissner, L. C., Sivertsen, B., Lindberg, E., Svensson, A. C., Hansson, S. O., Sundin, Ö., Hetta, J., et al. (2015) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2014.10.010 · Cited by 302 · see citing works
Grandner, M. A., Chakravorty, S., Perlis, M. L., Oliver, L., & Gurubhagavatula, I. (2014) · Sleep Medicine · doi:10.1016/j.sleep.2013.09.012 · Cited by 300 · see citing works
“For example, sleep duration may be related to unhealthy dietary patterns [47,120], decreased physical activity [121–123], and other health risk factors.”
Hartescu, I., Morgan, K., & Stevinson, C. D. (2015) · Journal of Sleep Research · doi:10.1111/jsr.12297 · Cited by 273 · see citing works
“A recent sleep trial (Reid et al., 2010) showed significant reductions in depressive symptoms among sedentary adults with chronic insomnia following a 16- week program of aerobic activity.”
BackgroundMethodInfluentialThe effects of physical activity on cortisol and sleep: A systematic review and meta-analysis.
De Nys, L., Anderson, K., Ofosu, E. F., Ryde, G. C., Connelly, J., & Whittaker, A. C. (2022) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2022.105843 · Cited by 279 · see citing works
“A table with characteristics of studies that were excluded after full-text screening (de Bruin, Formsma, Frijstein, & Bögels, 2017; Fouladbakhsh, Davis, & Yarandi, 2014; Garrido et al., 2017; Grahn Kronhed, Enthoven, Spångeus, & Willerton, 2020; Leone, Lalande, Thériault, Kalinova, & Fortin, 2018; Passos et al., 2014;…”
BackgroundEffects of exercise on mobility in people with Parkinson's disease
van der Kolk, N. M., & King, L. A. (2013) · Movement Disorders · doi:10.1002/mds.25658 · Cited by 235 · see citing works
Exercise can improve sleep quality: A systematic review and meta-analysis
Banno, M., Harada, Y., Taniguchi, M., Tobita, R., Tsujimoto, H., Tsujimoto, Y., Kataoka, Y., & Noda, A. (2018) · PeerJ · doi:10.7717/peerj.5172 · Cited by 246 · see citing works
“First, only four of the nine included trials examined adverse effects (Reid et al., 2010; Afonso et al., 2012; Hartescu, Morgan & Stevinson, 2015).”
BackgroundMethodInfluentialEffect of insomnia treatments on depression: A systematic review and meta-analysis
Gebara, M. A., Siripong, N., DiNapoli, E. A., Maree, R. D., Germain, A., Reynolds, C. F., Kasckow, J. W., Weiss, P. M., & Karp, J. F. (2018) · Depression and Anxiety · doi:10.1002/da.22776 · Cited by 247 · see citing works
“…reviewed (Buysse et al., 2011; Chen, Huang, Cheng, Li, & Chang, 2015; Germain et al., 2006; Germain et al., 2014; Hamoen, Redlich, & de Weerd, 2014; Manber et al., 2011; Reid et al., 2010; Taylor, Lichstein, Weinstock, Sanford, & Temple, 2007; Trockel, Manber, Chang, Thurston, & Taylor, 2011).”
The effect of resistance exercise on sleep: A systematic review of randomized controlled trials
Kovacevic, A., Mavros, Y., Heisz, J. J., & Fiatarone Singh, M. A. (2018) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2017.07.002 · Cited by 242 · see citing works
Goh, S. L., Persson, M. S. M., Stocks, J., Hou, Y., Welton, N. J., Lin, J., Hall, M. C., Doherty, M., & Zhang, W. (2019) · Sports Medicine · doi:10.1007/s40279-019-01082-0 · Cited by 246 · see citing works
Association between sleep disorders, obesity, and exercise: a review
Hargens, T. A., Kaleth, Edwards, E. S., & Butner (2013) · Nature and Science of Sleep · doi:10.2147/nss.s34838 · Cited by 242 · see citing works
“hygiene education, was shown to improve self-reported sleep quality, mood, and quality of life versus sleep hygiene education alone.(34) The effects in this study were reported to be comparable to other reported cognitive behavioral interventions.”
The impact of sleep on age-related sarcopenia: Possible connections and clinical implications
Piovezan, R. D., Abucham, J., dos Santos, R. V. T., de Mello, M. T., Tufik, S., & Poyares, D. R. (2015) · Ageing Research Reviews · doi:10.1016/j.arr.2015.07.003 · Cited by 215 · see citing works
“Aerobic exercise improves sleep efficiency and reduces depressive symptoms in older adults with insomnia (Reid et al., 2010).”
BackgroundXie, Y., Liu, S., Chen, X., Yu, H., Yang, Y., & Wang, W. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.664499 · Cited by 224 · see citing works
“Similarly, a 16-week program of moderate-intensity aerobic physical activity plus sleep hygiene education was effective in improving self-reported sleep quality, mood, and quality of life in older adults with chronic insomnia (21).”
BackgroundMora, J. C., & Valencia, W. M. (2018) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2017.08.007 · Cited by 196 · see citing works
Schroeder, A., & Colwell, C. S. (2013) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2013.09.002 · Cited by 190 · see citing works
Exercise to Improve Sleep in Insomnia: Exploration of the Bidirectional Effects
Baron, K., Reid, K., & Zee, P. (2013) · Journal of Clinical Sleep Medicine (JCSM) · doi:10.5664/jcsm.2930 · Cited by 175 · see citing works
“20 This analysis extends these findings by evaluating the day-to-day relationships between exercise and sleep.”
Self-citationSalerno, E. A., Ehlers, D. K., Aguiñaga, S., Daugherty, A. M., Kramer, A. F., & McAuley, E. (2017) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2017.06.005 · Cited by 190 · see citing works
Effects of moderate aerobic exercise training on chronic primary insomnia
Passos, G. S., Poyares, D., Santana, M. G., D’Aurea, C. V. R., Youngstedt, S. D., Tufik, S., & de Mello, M. T. (2011) · Sleep Medicine · doi:10.1016/j.sleep.2011.02.007 · Cited by 182 · see citing works
“However, there has been very limited experimental investigation of the effects of aerobic exercise training on sleep in individuals with insomnia [18,19].”
BackgroundResultInfluentialAdvances in the management of chronic insomnia
Kay-Stacey, M., & Attarian, H. P. (2016) · BMJ · doi:10.1136/bmj.i2123 · Cited by 163 · see citing works
Rubio-Arias, J. Á., Marín-Cascales, E., Ramos-Campo, D. J., Hernandez, A. V., & Pérez-López, F. R. (2017) · Maturitas · doi:10.1016/j.maturitas.2017.04.003 · Cited by 159 · see citing works
Association between objectively-measured physical activity and sleep, NHANES 2005–2006
Loprinzi, P. D., & Cardinal, B. J. (2011) · Mental Health and Physical Activity · doi:10.1016/j.mhpa.2011.08.001 · Cited by 154 · see citing works
Ethnomedicinal plant diversity in Thailand
Phumthum, M., Srithi, K., Inta, A., Junsongduang, A., Tangjitman, K., Pongamornkul, W., Trisonthi, C., & Balslev, H. (2017) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2017.12.003 · Cited by 146 · see citing works
Effects of Physical Exercise on Depressive Symptoms and Biomarkers in Depression
Archer, T., Josefsson, T., & Lindwall, M. (2015) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527313666141130203245 · Cited by 147 · see citing works
“Pittsburgh Sleep Quality Index, sleep latency, sleep duration, sleep efficiency and daytime dysfunction compared to controls (121).”
Nuutinen, T., Ray, C., & Roos, E. (2013) · BMC Public Health · doi:10.1186/1471-2458-13-684 · Cited by 145 · see citing works
“An indirect pathway may also explain the association between computer use, TV viewing and sleep; for example, computer use or TV viewing may displace physical activity [5], which is known to promote good quality sleep [6].”
BackgroundChan, J. S. M., Ho, R. T. H., Chung, K.-F., Wang, C.-W., Yao, T.-J., Ng, S.-M., & Chan, C. L. W. (2014) · Evidence-Based Complementary and Alternative Medicine · doi:10.1155/2014/106048 · Cited by 138 · see citing works
“A number of studies have reported that aerobic exercise has positive effect on sleep quality in patients with chronic insomnia [23, 24] and obstructive sleep apnea [25]; and several studies have shown that Qigong exercise improves sleep quality in patients with fibromyalgia [26, 27], perimenopausal women [28], and com…”
BackgroundSleep quality in cigarette smokers: Associations with smoking-related outcomes and exercise
Purani, H., Friedrichsen, S. C., & Allen, A. M. (2018) · Addictive Behaviors · doi:10.1016/j.addbeh.2018.10.023 · Cited by 127 · see citing works
A Longitudinal Examination of Sleep Quality and Physical Activity in Older Adults
Holfeld, B., & Ruthig, J. (2014) · Journal of Applied Gerontology · doi:10.1177/0733464812455097 · Cited by 119 · see citing works
“Past studies have examined only one causal direction in this association, primarily focusing on examining whether physical activity predicts sleep quality (Benloucif et al., 2004; King et al., 2008; Reid et al., 2010).”
BackgroundResultInfluentialIs exercise an alternative treatment for chronic insomnia?
Passos, G. S., Poyares, D. L. R., Santana, M. G., Tufik, S., & de Mello, M. T. (2012) · Clinics · doi:10.6061/clinics/2012(06)17 · Cited by 131 · see citing works
“Some studies have investigated the effects of exercise on middle-aged adults with chronic insomnia using PSG, actigraphy or subjective sleep measures (PSQI or sleep diary) (27,35,38).”
BackgroundInfluentialOmachi, T. A. (2011) · Arthritis Care & Research · doi:10.1002/acr.20544 · Cited by 129 · see citing works
Does exercise improve sleep for adults with insomnia? A systematic review with quality appraisal
Lowe, H., Haddock, G., Mulligan, L. D., Gregg, L., Fuzellier-Hart, A., Carter, L.-A., & Kyle, S. D. (2019) · Clinical Psychology Review · doi:10.1016/j.cpr.2018.11.002 · Cited by 121 · see citing works
“Whilst the latter study (Reid et al., 2010) scored above the cut-off on the CTAM, the overall sampling characteristics did not achieve a quality score (>0).”
BackgroundMethodInfluentialTanaka, E., Yatsuya, H., Uemura, M. Y., Murata, C., Otsuka, R., Toyoshima, H., Tamakoshi, K., Sasaki, S., Kawaguchi, L., & Aoyama, A. (2013) · Journal of Epidemiology · doi:10.2188/jea.je20120101 · Cited by 116 · see citing works
Sheng, P., Hou, L., Wang, X., Wang, X., Huang, C.-G., Yu, M., Han, X., & Dong, Y. (2013) · PLoS ONE · doi:10.1371/journal.pone.0081802 · Cited by 113 · see citing works
“Hence, both pharmacological and non-pharmacological therapies have been applied in the management of fatigue and EDS [21-24].”
BackgroundTemporal Relationships between Physical Activity and Sleep in Older Women
Lambiase, M. J., Gabriel, K. P., Kuller, L. H., & Matthews, K. A. (2013) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31829e4cea · Cited by 110 · see citing works
“For example, acute bouts of exercise and exercise interventions have produced positive effects on sleep in some (9,13,24,28) but not all studies (7,21,35).”
BackgroundHarding, A., Gonder, U., Robinson, S. J., Crean, S., & Singhrao, S. K. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00398 · Cited by 106 · see citing works
“Finally, exercise taken during the day can have a positive impact on sleep, especially when undertaken outside in natural daylight (Reid et al., 2010).”
Insufficient Sleep Syndrome: Is it time to classify it as a major noncommunicable disease?
Chattu, V. K., Sakhamuri, S. M., Kumar, R., Spence, D. W., BaHammam, A. S., & Pandi-Perumal, S. R. (2018) · Sleep Science · doi:10.5935/1984-0063.20180013 · Cited by 104 · see citing works
“Additionally, it should be recommended that exercise be included as a daily habit, inasmuch as exercise is known to be associated with improved sleep outcomes 103,104 .”
BackgroundPhysical Activity and Cognition: A Mediating Role of Efficient Sleep
Wilckens, K. A., Erickson, K. I., & Wheeler, M. E. (2016) · Behavioral Sleep Medicine · doi:10.1080/15402002.2016.1253013 · Cited by 105 · see citing works
“The moral rights of the named author(s) have been asserted. sleep latency, and sleep depth (Kline et al., 2013; Montgomery & Dennis, 2002; Reid et al., 2010; Tworoger et al., 2003; Youngstedt, 2005).”
BackgroundResultPassos, G. S., Poyares, D., Santana, M. G., Teixeira, A. A. D. S., Lira, F. S., Youngstedt, S. D., Santos, R. V. T. D., Tufik, S., & de Mello, M. T. (2014) · BioMed Research International · doi:10.1155/2014/498961 · Cited by 99 · see citing works
Tseng, T.-H., Chen, H., Wang, L., & Chien, M. (2020) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.8560 · Cited by 112 · see citing works
“25 hours.(38) In our study, the self-reported sleep duration showed a mean increase of 1.”
Bademli̇, K., Lök, N., Canbaz, M., & Lök, S. (2018) · Perspectives In Psychiatric Care · doi:10.1111/ppc.12324 · Cited by 102 · see citing works
Knowles, A., Herbert, P., Easton, C., Sculthorpe, N. F., & Grace, F. (2015) · AGE · doi:10.1007/s11357-015-9763-3 · Cited by 103 · see citing works
“Previous research has shown that various types of exercise training (e.g. aerobic , strength, functional strength and flexibility) increase perceptions of HRQL in older adults (Reid et al. 2010; Rejeski and Mihalko 2001).”
BackgroundInfluentialKadariya, S., Gautam, R. K., & Aro, A. R. (2019) · BioMed Research International · doi:10.1155/2019/6752182 · Cited by 99 · see citing works
An, J., Sun, Y., Wan, Y., Chen, J., Wang, X., & Tao, F. (2014) · Journal of Addiction Medicine · doi:10.1097/adm.0000000000000026 · Cited by 90 · see citing works
“, 2004), which was known to promote good quality of sleep (Block, 2008; Reid et al., 2010).”
BackgroundAmspoker, A. B., Armento, M. E. A., Weiss, B. J., Rhoades, H. M., Novy, D. M., WILSON, N. L., Kunik, M. E., & Stanley, M. A. (2012) · Psychiatry Research · doi:10.1016/j.psychres.2012.03.045 · Cited by 86 · see citing works
“…dimensions of perceived sleep quality and impairment, outcome studies assessing treatment response for insomnia in older adults (Lai and Good, 2004; Reid et al., 2010) and the utility of CBT for insomnia and pain management (Morgan et al., 2004; Cunningham et al., 2011) have exclusively examined…”
Araghi, M., Jagielski, A. C., Neira, I., Brown, A. C., Higgs, S., Thomas, G. N., & Taheri, S. (2013) · SLEEP · doi:10.5665/sleep.3216 · Cited by 90 · see citing works
Schega, L., Peter, B., Törpel, A., Mutschler, H., Isermann, B., & Hamacher, D. (2013) · Gerontology · doi:10.1159/000350927 · Cited by 85 · see citing works
Kline, C. E., Irish, L. A., Krafty, R. T., Sternfeld, B., Kravitz, H. M., Buysse, D. J., Bromberger, J. T., Dugan, S. A., & Hall, M. H. (2013) · SLEEP · doi:10.5665/sleep.2946 · Cited by 85 · see citing works
Voluntary exercise can strengthen the circadian system in aged mice
Leise, T., Harrington, M. E., Molyneux, P. C., Song, I., Queenan, H., Zimmerman, E., Lall, G. S., & Biello, S. M. (2013) · AGE · doi:10.1007/s11357-012-9502-y · Cited by 84 · see citing works
“…wheels can alter key properties of rodent circadian rhythms such as period and rate of resynchronization (Castillo et al. 2011; Harrington et al. 2007) and exercise can also benefit consolidation of sleep and activity rhythms in people (King et al. 1997; Passos et al. 2011; Reid et al. 2010).”
BackgroundThe impact of exercise on sleep and sleep disorders
Korkutata, A., Korkutata, M., & Lazarus, M. (2025) · npj Biological Timing and Sleep · doi:10.1038/s44323-024-00018-w · Cited by 101 · see citing works
“In a study involving 17 sedentary adultsover55 with insomnia, combining aerobic exercise with sleep hygiene improved various aspects of sleep quality compared with a control group 141 .”
Physical Activity and Sleep Quality Association in Different Populations: A Meta-Analysis
Zhao, H., Lu, C., & Yi, C. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20031864 · Cited by 79 · see citing works
Aerobic exercise modulates cytokine profile and sleep quality in elderly
El-Kader, S. M. A., & Al-Jiffri, O. H. (2019) · African Health Sciences · doi:10.4314/ahs.v19i2.45 · Cited by 78 · see citing works
Prospective Study of Physical Activity and Sleep in Middle-Aged and Older Adults
Tsunoda, K., Kitano, N., Kai, Y., Uchida, K., Kuchiki, T., Okura, T., & Nagamatsu, T. (2015) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2014.12.006 · Cited by 80 · see citing works
Effects of resistance exercise training and stretching on chronic insomnia
D’Aurea, C. V. R., Poyares, D. R., Passos, G. S., Santana, M. G., Youngstedt, S. D., de Souza, A. A. L., Bicudo, J., Tufik, S., & de Mello, M. T. (2018) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2018-0030 · Cited by 81 · see citing works
Koolhaas, C. M., Dhana, K., van Rooij, F. J. A., Schoufour, J. D., Albert Hofman, D., & Franco, O. H. (2017) · The journal of nutrition health & aging · doi:10.1007/s12603-017-0902-7 · Cited by 72 · see citing works
“Data from randomized controlled trials indicate that exercise has a positive effect on quality of life in older adults with insomnia (24) and minor depression (25) and can reduce pain among individuals with osteoarthritis (26, 27).”
Kline, C. E., Ewing, G. B., Burch, J. B., Blair, S. N., Durstine, J. L., Davis, J. M., & Youngstedt, S. D. (2012) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.2022 · Cited by 81 · see citing works
A community-based cross-sectional study of sleep quality in middle-aged and older adults
Zhang, H., Li, Y., Mo, H., Qiu, D.-X., Zhao, J., Luo, J., Lin, W., Wang, J., & Wang, P.-X. (2016) · Quality of Life Research · doi:10.1007/s11136-016-1408-1 · Cited by 73 · see citing works
“Similar results were found in Gerber and Reid’s studies [32, 42].”
ResultHealthy cognitive ageing in the Lothian Birth Cohort studies: marginal gains not magic bullet
Corley, J., Cox, S. R., & Deary, I. J. (2017) · Psychological Medicine · doi:10.1017/s0033291717001489 · Cited by 68 · see citing works
“2012a, b), improving sleep quality and minimising pain (Reid et al. 2010), all of which may secondarily impact neurocognitive functioning (Reppermund et al.”
BackgroundEvidence of association between sleep quality and APOE ε4 in healthy older adults
Drogos, L. L., Gill, S. J., Tyndall, A. V., Raneri, J. K., Parboosingh, J. S., Naef, A. C., Guild, K. D., Eskes, G. A., Hanly, P. J., & Poulin, M. J. (2016) · Neurology · doi:10.1212/wnl.0000000000003255 · Cited by 78 · see citing works
“In addition, improving sleep in the older adult population has been linked with improved quality of life, regardless of health status.(34,35) One of the most effective interventions to improving sleep within the older adult population is aerobic exercise.”
BackgroundBrand, S., Kalak, N., Gerber, M., Kirov, R., Pühse, U., & Holsboer‐Trachsler, E. (2014) · Sleep Medicine · doi:10.1016/j.sleep.2014.05.016 · Cited by 77 · see citing works
“[8] assessed 17 subjects aged 61 years suffering from insomnia, and after a 16-week exercise intervention an increase in subjective sleep, mood and vitality was reported.”
BackgroundLifestyle Choices and Brain Health
Mintzer, J. E., Donovan, K. A., Kindy, A. Z., Lock, S. L., Chura, L. R., & Barracca, N. (2019) · Frontiers in Medicine · doi:10.3389/fmed.2019.00204 · Cited by 72 · see citing works
The Role of the Work Context in Multiple Wellness Outcomes for Hospital Patient Care Workers
Sorensen, G., Stoddard, A. M., Stoffel, S. D., Buxton, O. M., Sembajwe, G. N., Hashimoto, D. M., Dennerlein, J. T., & Hopcia, K. L. (2011) · Journal of Occupational and Environmental Medicine · doi:10.1097/jom.0b013e318226a74a · Cited by 74 · see citing works
“68 The lack of association of either sleep or physical activity to LBP is contrary to our hypothesis and is in contrast to prior research which has shown a relationship between sedentary behavior and increased risk for MSDs of both the low back and neck.”
Aging, circadian rhythms and depressive disorders: a review.
Costa, I. C., Carvalho, H. N., & Fernandes, L. P. N. S. (2013) · Europe PMC (PubMed Central) · Cited by 90 · see citing works
Magzal, F., Shochat, T., Haimov, I., Tamir, S., Asraf, K., Arieli, M., Even, C., & Agmon, M. (2022) · Scientific Reports · doi:10.1038/s41598-022-05099-w · Cited by 70 · see citing works
Baglioni, C., Bostanova, Z., Bacaro, V., Benz, F., Hertenstein, E., Spiegelhalder, K., Rücker, G., Frase, L., Riemann, D. W., & Feige, B. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9061949 · Cited by 71 · see citing works
“Of the remaining studies, seven used criteria consistent with DSM-5 categorization [60,62,64,67,85,89,94].”
BackgroundMethodInfluentialDavidson, C. L., Babson, K. A., Bonn‐Miller, M. O., Souter, T., & Vannoy, S. (2013) · Suicide and Life-Threatening Behavior · doi:10.1111/sltb.12014 · Cited by 71 · see citing works
Zhai, X., Wu, N., Koriyama, S., Wang, C., Shi, M., Huang, T., Wang, K., Sawada, S. S., & Xiang, F. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18010289 · Cited by 69 · see citing works
“, aerobic and endurance exercise) PA [19,20] have positive effects on SQ, some cross-sectional research has indicated that no correlation between PA and SQ has been observed [21–23].”
BackgroundPrevalence and Predictors of Poor Sleep Quality in Mild Cognitive Impairment
McKinnon, A. C., Terpening, Z., Hickie, I. B., Batchelor, J., Grunstein, R. R., Lewis, S. J. G., & Naismith, S. L. (2014) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988714527516 · Cited by 70 · see citing works
“Additionally, it is likely that key components of exercise such as aerobic exercise and muscle strengthening exercises are more crucial to sleep quality than simple time measures.(57,58) Thus, our assessment of exercise may have been insufficient for these purposes.”
BackgroundFactors Associated with Psychological Distress and Physical Activity During the COVID-19 Pandemic
Sfendla, A., & Hadrya, F. (2020) · Health Security · doi:10.1089/hs.2020.0062 · Cited by 71 · see citing works
Guallar‐Castillón, P., Bayán-Bravo, A., León-Muñoz, L. M., Balboa‐Castillo, T., López‐García, E., Gutiérrez-Fisac, J. L., & Rodríguez‐Artalejo, F. (2014) · Preventive Medicine · doi:10.1016/j.ypmed.2014.08.015 · Cited by 67 · see citing works
Al-Sharman, A., Khalil, H., El-Salem, K., Aldughmi, M., & Aburub, A. (2019) · NeuroRehabilitation · doi:10.3233/nre-192748 · Cited by 71 · see citing works
“A recent study showed that aerobic exercise is an effective treatment approach to improve sleep quality, mood and quality of life in older adults with chronic insomnia (Reid et al., 2010).”
Oudegeest‐Sander, M. H., Eijsvogels, T. M. H., Verheggen, R. J. H. M., Poelkens, F., Hopman, M. T. E., Jones, H., & Thijssen, D. H. J. (2012) · Gerontology · doi:10.1159/000342213 · Cited by 63 · see citing works
Amiri, S., Hasani, J., & Satkin, M. (2021) · Sleep Medicine · doi:10.1016/j.sleep.2021.05.013 · Cited by 69 · see citing works
Automatic Sleep Staging Employing Convolutional Neural Networks and Cortical Connectivity Images
Chriskos, P., Frantzidιs, C. A., Gkivogkli, P. T., Bamidis, P. D., & Kourtidou‐Papadeli, C. (2019) · IEEE Transactions on Neural Networks and Learning Systems · doi:10.1109/tnnls.2019.2899781 · Cited by 65 · see citing works
“diseases, diabetes, cognitive decline, and loss of everyday life quality [2].”
BackgroundMein, G., & Grant, R. (2018) · BMC Geriatrics · doi:10.1186/s12877-018-0867-3 · Cited by 66 · see citing works
“[19] reported increased activity levels in older adults improved sleep quality.”
BackgroundRimmer, J. H., & Lai, B. W. (2015) · Disability and Rehabilitation · doi:10.3109/09638288.2015.1047967 · Cited by 60 · see citing works
“[62], hyperlipidemia, type 2 diabetes [63,64], falls [65], poor sleep quality [66], depression [67] and many others.”
BackgroundSleep quality and the menstrual cycle
Romans, S. E., Kreindler, D., Einstein, G., Laredo, S., Petrovic, M. J., & Stanley, J. (2015) · Sleep Medicine · doi:10.1016/j.sleep.2014.12.001 · Cited by 63 · see citing works
“The current evidence on associations between sleep quality and exercise/physical activity is contradictory, with some studies reporting a positive link [31,50,51] and others not [48].”
MethodResultPhysical activity, sedentary behaviour and sleep in COPD guidelines: A systematic review
Lewthwaite, H., Effing, T., Olds, T., & Williams, M. (2017) · Chronic Respiratory Disease · doi:10.1177/1479972316687224 · Cited by 62 · see citing works
“Spending more time in active pursuits may also help to improve sleep quality.(13) Sleep quality has shown to be a predictor of mortality, COPD-hospitalization, health-related quality of life and severity of day time symptoms.”
BackgroundEffect of different types of exercise on sleep quality of elderly subjects
Bonardi, J. M. T., Lima, L. G., Campos, G. O., Bertani, R. F., Moriguti, J. C., Ferriolli, E., & Lima, N. K. C. (2016) · Sleep Medicine · doi:10.1016/j.sleep.2016.06.025 · Cited by 66 · see citing works
Abid, R., Ammar, A., Maaloul, R., Souissi, N., & Hammouda, O. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18063065 · Cited by 62 · see citing works
“In this way, exercise has long been considered as a non-pharmacological treatment option for sleep disturbances [27].”
BackgroundÎnoue, S., Yorifuji, T., Sugiyama, M., Ohta, T., Ishikawa-Takata, K., & Doi, H. (2013) · Journal of Aging and Physical Activity · doi:10.1123/japa.21.2.119 · Cited by 64 · see citing works
“Among these approaches, physical activity is considered an effective and relatively easy intervention to prevent insomnia (Driver & Taylor, 2000; Paparrigopoulos, Tzavara, Theleritis, Soldatos, & Tountas, 2010; Reid et al., 2010; Sherrill, Kotchou, & Quan, 1998; Singh, Clements, & Fiatarone, 1997).”
BackgroundAutonomic dysregulation and sleep homeostasis in insomnia
Grimaldi, D., Reid, K. J., Papalambros, N. A., Braun, R., Malkani, R. G., Abbott, S. M., Ong, J. C., & Zee, P. C. (2020) · SLEEP · doi:10.1093/sleep/zsaa274 · Cited by 60 · see citing works
“The following procedures were conducted: (1) nightly PSG; (2) three daytime blood pressure (BP) and heart rate (HR) measurements; (3) oral glucose tolerance test on the morning of day 2 of admission; and (4) on the last day (day 4), a 24-h period of serial blood draws [42].”
BackgroundMethodSelf-citationNo Evidence of Reciprocal Associations between Daily Sleep and Physical Activity
Mitchell, J. A., Godbole, S. V., Moran, K., Murray, K. E., James, P., Laden, F., Hipp, J. A., Kerr, J., & Glanz, K. (2016) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000001000 · Cited by 54 · see citing works
“In addition, the women enrolled in these studies were all overweight/obese, physically inactive, and postmenopausal at enrollment (20,22, 23,30,34), and in one study, the women were diagnosed with insomnia (30).”
BackgroundInfluentialExercise improves learning and memory impairments in sleep deprived female rats
Saadati, H., Esmaeili‐Mahani, S., Esmaeilpour, K., Nazeri, M., Mazhari, S., & Sheibani, V. (2014) · Physiology & Behavior · doi:10.1016/j.physbeh.2014.10.006 · Cited by 57 · see citing works
Does Dog Ownership Affect Physical Activity, Sleep, and Self-Reported Health in Older Adults?
Mičková, E., Machová, K., Daďová, K., & Svobodová, I. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16183355 · Cited by 55 · see citing works
“Specifically, older adults with high PA experience an increase in overall sleep time, sleep efficiency, improved sleep quality, and a lower incidence of sleep disorders [17].”
BackgroundLøppenthin, K. B., Esbensen, B. A., Østergaard, M., Jennum, P., Tolver, A., Aadahl, M., Thomsen, T., & Midtgaard, J. (2015) · Rheumatology International · doi:10.1007/s00296-015-3274-5 · Cited by 56 · see citing works
Lifestyle Factors and Sleep Health across the Lifespan
Dzierzewski, J. M., Sabet, S. M., Ghose, S. M., Perez, E., Soto, P. F., Ravyts, S. G., & Dautovich, N. D. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18126626 · Cited by 58 · see citing works
“Lastly, health providers should assess physical activity and levels of sedentary behavior in older adults when evaluating sleep health [36,41,42].”
BackgroundAge-Related Decline in Controlled Retrieval: The Role of the PFC and Sleep
Wilckens, K., Erickson, K., & Wheeler, M. E. (2012) · Journal of Neural Transplantation and Plasticity · doi:10.1155/2012/624795 · Cited by 55 · see citing works
“Subjective sleep quality has also been shown to improve with chronic exercise [157, 158].”
BackgroundChronotherapies for Parkinson’s disease
Fifel, K., & Videnović, A. (2019) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2019.01.002 · Cited by 58 · see citing works
“Similarly, in older adults with insomnia, sleep quality also improved when exercise was performed during the afternoon or early evening (Reid et al., 2010).”
BackgroundMorita, Y., Sasai-Sakuma, T., & Inoue, Y. (2017) · Sleep Medicine · doi:10.1016/j.sleep.2017.03.014 · Cited by 55 · see citing works
McGowan, L. J., Devereux‐Fitzgerald, A., Powell, R., & French, D. (2017) · International Review of Sport and Exercise Psychology · doi:10.1080/1750984x.2016.1272705 · Cited by 53 · see citing works
“Physical activity additionally helps to prevent frailty, loss of independence (Paterson & Warburton, 2010; Peterson et al., 2009), and cognitive decline (e.g., Guiney & Machado, 2013), and improves mood, sleep, and quality of life (Reid et al., 2010) in older adults.”
BackgroundExercise and Sleep in Community-Dwelling Older Adults
Varrasse, M., Li, J., & Gooneratne, N. S. (2015) · Current Sleep Medicine Reports · doi:10.1007/s40675-015-0028-6 · Cited by 53 · see citing works
- Authors
- Reid, K. J., Baron, K. G., Lu, B., Naylor, E., Wolfe, L., & Zee, P. C.
- Affiliations
- Northwestern University (US)
- Corresponding author
- Zee, Phyllis C.
- Venue
- Sleep Medicine
- Publisher
- Elsevier BV
- Published
- 2010-10
- Volume
- 11
- Issue
- 9
- Pages
- 934-940
- ISSN
- 1389-9457 (ISSN-L)
- PMC
- PMC2992829
- OpenAlex
- W2061105741
- Cited by
- 665
- References
- 57
- Citations by year
- 2026: 39 · 2025: 40 · 2024: 57 · 2023: 36 · 2022: 71 · 2021: 45 · 2020: 39 · 2019: 43 · 2018: 54 · 2017: 43 · 2016: 38 · 2015: 43 · 2014: 44 · 2013: 31 · 2012: 26
- FWCI
- 30.56
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- Locations
- Sleep Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Aging (K23 HL091508, M01 RR00048, P01 AG11412, T32AG020506)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Keywords
- aerobic exercise, chronic insomnia, older adults, sleep hygiene education, sleep quality, mood, quality of life, depressive symptoms, daytime sleepiness, sleep latency, physical activity interventions
- MeSH terms
- Affect, Depression, Exercise Therapy, Female, Humans, Sleep Initiation and Maintenance Disorders, Male, Middle Aged, Patient Compliance, Psychiatric Status Rating Scales, Quality of Life, Sleep, Exercise, Polysomnography, Sedentary Behavior
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