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The Emerging Science of Interoception: Sensing, Integrating, Interpreting, and Regulating Signals within the Self
Open accessAbstract
Interoception refers to the representation of the internal states of an organism, and includes the processes by which it senses, interprets, integrates, and regulates signals from within itself. This review presents a unified research framework and attempts to offer definitions for key terms to describe the processes involved in interoception. We elaborate on these definitions through illustrative research findings, and provide brief overviews of central aspects of interoception, including the anatomy and function of neural and non-neural pathways, diseases and disorders, manipulations and interventions, and predictive modeling. We conclude with discussions about major research gaps and challenges.
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“From a PNE perspective, interoceptive skills-building helps the person notice relationships between inputs (physiology, and BPS factors that influence threat or safety), and the output/experience of pain.58,59”
From Remotely Delivered Psychologically Informed Mindful Movement Physical Therapy for Pain Care: A Framework for Operationalization (2023) · cites this paper as [58]
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“These insights empower the person to recognize their own unique triggers with less judgement, to build trust in themselves, and to find ways to change the relationships and reactions to these bodily activations.”
From Remotely Delivered Psychologically Informed Mindful Movement Physical Therapy for Pain Care: A Framework for Operationalization (2023) · cites this paper as [58]
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“The interoceptive sensation is mediated by two primary ascending neural pathways: the spinal nerve pathway and the vagal nerve pathway [55].”
From The Insular Cortex: An Interface Between Sensation, Emotion and Cognition (2024) · cites this paper as [55]
In the citing paper
“Interoception impairment (i.e., difficulties in the sensing, perceiving, and anticipating of signals arising from within the body) is a core feature that can occur in multiple clinical conditions.1, 2, 3”
From Altered spatiotemporal brain dynamics of interoception in behavioural-variant frontotemporal dementia (2025) · cites this paper as [2]
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Cites
Dissociable intrinsic connectivity networks for salience processing and executive control
Seeley, W. W., Menon, V., Schatzberg, A. F., Keller, J., Glover, G. H., Kenna, H., Reiss, A. L., & Greicius, M. D. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.5587-06.2007 · Cited by 7,426
How do you feel — now? The anterior insula and human awareness
(Bud) Craig, A. D. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2555 · Cited by 6,657
How do you feel? Interoception: The sense of the physiological condition of the body
Craig, A. D. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn894 · Cited by 6,006
Neural systems supporting interoceptive awareness
Critchley, H. D., Wiens, S., Rotshtein, P., Öhman, A., & Dolan, R. J. (2004) · Nature Neuroscience · doi:10.1038/nn1176 · Cited by 3,406
Interoception and Mental Health: A Roadmap.
Khalsa, S. S., Adolphs, R., Cameron, O. G., Critchley, H. D., Davenport, P. W., Feinstein, J. S., Feusner, J. D., Garfinkel, S. N., Lane, R. D., Mehling, W. E., et al. (2018) · Biological psychiatry. Cognitive neuroscience and neuroimaging · doi:10.1016/j.bpsc.2017.12.004 · Cited by 1,453
Swanson, L. W., & Petrovich, G. D. (1998) · Trends in Neurosciences · doi:10.1016/s0166-2236(98)01265-x · Cited by 1,351
Kurth, F., Zilles, K., Fox, P. T., Laird, A. R., & Eickhoff, S. B. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0255-z · Cited by 1,293
Structure and Function of the Human Insula
Uddin, L. Q., Nomi, J. S., Hébert-Seropian, B., Ghaziri, J., & Boucher, O. (2017) · Journal of Clinical Neurophysiology · doi:10.1097/wnp.0000000000000377 · Cited by 1,262
Visceral influences on brain and behavior
Critchley, H. D., & Harrison, N. A. (2013) · Neuron · doi:10.1016/j.neuron.2013.02.008 · Cited by 1,177
Insula of the old world monkey. III: Efferent cortical output and comments on function
Mesulam, M. ‐., & Mufson, E. J. (1982) · Journal of Comparative Neurology · doi:10.1002/cne.902120104 · Cited by 1,013
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Cardiogenic control of affective behavioural state
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Anterior insula as a gatekeeper of executive control
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Interventions and Manipulations of Interoception
Weng, H. Y., Feldman, J. L., Leggio, L., Napadow, V., Park, J., & Price, C. J. (2020) · Trends in Neurosciences · doi:10.1016/j.tins.2020.09.010 · Cited by 250
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Zhao, Q., Yu, C. D., Wang, R., Xu, Q. J., Pra, R. D., Zhang, L., & Chang, R. B. (2022) · Nature · doi:10.1038/s41586-022-04515-5 · Cited by 243
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Engelen, T., Solcà, M., & Tallon-Baudry, C. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01425-1 · Cited by 207
Atypical interoception as a common risk factor for psychopathology: A review
Brewer, R., Murphy, J., & Bird, G. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.07.036 · Cited by 180
Interoception of breathing and its relationship with anxiety
Harrison, O. K., Köchli, L., Marino, S., Luechinger, R., Hennel, F., Brand, K., Hess, A. J., Frässle, S., Iglesias, S., Vinckier, F., et al. (2021) · Neuron · doi:10.1016/j.neuron.2021.09.045 · Cited by 163
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Candia‐Rivera, D., Catrambone, V., Thayer, J. F., Gentili, C., & Valenza, G. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2119599119 · Cited by 176
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Zhang, R., Deng, H., & Xiao, X. (2024) · Neuroscience Bulletin · doi:10.1007/s12264-024-01211-4 · Cited by 158
AgRP neurons: Regulators of feeding, energy expenditure, and behavior
Deem, J. D., Faber, C. L., & Morton, G. J. (2021) · FEBS Journal · doi:10.1111/febs.16176 · Cited by 171
Legrand, N., Nikolova, N. E., Corrêa, C. M. C., Brændholt, M., Stuckert, A., Mathiasen, N. K., Vejlø, M., Fardo, F., & Allen, M. (2021) · Biological Psychology · doi:10.1016/j.biopsycho.2021.108239 · Cited by 162
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Feldman, M. J., Bliss-Moreau, E., & Lindquist, K. A. (2024) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2024.01.009 · Cited by 101
Qiao, W., Pan, D., Zheng, Y., Wu, S., Liu, X., Chen, Z., Wan, M., Feng, S., Cheung, K., Yeung, K., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-28203-0 · Cited by 103
Chen, W., Iversen, J. R., Kao, M. H., Loui, P., Patel, A. D., Zatorre, R. J., & Edwards, E. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.1135-22.2022 · Cited by 106
Self-citationFascia Mobility, Proprioception, and Myofascial Pain.
Langevin, H. M. (2021) · Life · doi:10.3390/life11070668 · Cited by 97
“This definition includes proprioception in its broadest sense, meaning the sensory perception and awareness of the position and movement of the body [12].”
BackgroundSelf-citationThe new measures of interoceptive accuracy: A systematic review and assessment
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Dalghi, M. G., Ruiz, W. G., Clayton, D. R., Montalbetti, N., Daugherty, S. L., Beckel, J. M., Carattino, M. D., & Apodaca, G. L. (2021) · JCI Insight · doi:10.1172/jci.insight.152984 · Cited by 106
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Liu, W., Chen, W., Xie, M., Chen, C., Shao, Z., Zhang, Y., Zhao, H., Song, Q., Hu, H., Xing, X., et al. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01457-w · Cited by 85
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Desmedt, O., Luminet, O., Maurage, P., & Corneille, O. (2025) · Perspectives on Psychological Science · doi:10.1177/17456916231191537 · Cited by 80
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Williams, Z. J., Suzman, E., Bordman, S. L., Markfeld, J. E., Kaiser, S., Dunham, K., Zoltowski, A. R., Failla, M. D., Cascio, C. J., & Woynaroski, T. G. (2022) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-022-05656-2 · Cited by 69
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Metadata
- Authors
- Chen, W. G., Schloesser, D., Arensdorf, A. M., Simmons, J. M., Cui, C., Valentino, R., Gnadt, J. W., Nielsen, L., Hillaire-Clarke, C. S., Spruance, V., Horowitz, T. S., Vallejo, Y. F., & Langevin, H. M.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- Chen, Wen G.
- Venue
- Trends in Neurosciences
- Publisher
- Elsevier BV
- Published
- 2021-01
- Volume
- 44
- Issue
- 1
- Pages
- 3-16
- ISSN
- 0166-2236 (ISSN-L)
- PMC
- PMC7780231
- OpenAlex
- W3115649676
- Cited by
- 707
- References
- 119
- Citations by year
- 2026: 145 · 2025: 155 · 2024: 138 · 2023: 133 · 2022: 85 · 2021: 48
- FWCI
- 11.16
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Trends in Neurosciences (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- NIH Blueprint for Neuroscience Research
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
- Keywords
- interoception, interoceptive signals, signal integration, neural pathways, predictive modeling, research framework
- MeSH terms
- Humans, Interoception
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