Cited by 486Pharmaceutical and Antibiotic Environmental ImpactsWastewater Treatment and ReuseEffects and risks of endocrine disrupting chemicals

Wastewater-based epidemiology biomarkers: Past, present and future

Choi, Phil M., Tscharke, Ben J., Donner, Erica, O'Brien, Jake W., Grant, Sharon C., Kaserzon, Sarit L., Mackie, Rachel, O'Malley, Elissa +3 more·2018·TrAC Trends in Analytical Chemistry

Abstract

Wastewater is a complex matrix containing a wide range of chemical and biological markers of human activity. Relating concentrations of these "waste" materials in wastewater influent streams to population-scale use, consumption, or rates of exposure, can provide important qualitative or quantitative information on the activity of inhabitants within a given wastewater catchment. Many publications in this field of study have focussed on the usage of pharmaceuticals, illicit drugs, tobacco and alcohol. However, many other potential applications are emerging which can contribute useful knowledge on human health, exposure to industrial chemicals, infectious diseases or pathogens and antibiotic resistance. This review summarises the established wastewater based epidemiology (WBE) biomarkers, and presents a critical review of the current capabilities of WBE. We further discuss possible future strategies and challenges anticipated in analysing wastewater to measure chemical markers of population health as well as biological markers of microbial exposure and disease. (c) 2018 Elsevier B.V. All rights reserved.

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Crossref · 10.1016/j.trac.2018.06.004

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Authors
Choi, P. M., Tscharke, B. J., Donner, E., O'Brien, J. W., Grant, S. C., Kaserzon, S. L., Mackie, R., O'Malley, E., Crosbie, N. D., Thomas, K. V., & Mueller, J. F.
Affiliations
  • The University of Queensland (AU)
  • University of South Australia (AU)
  • Melbourne Water (AU)
Corresponding author
Thomas, Kevin V.
Venue
TrAC Trends in Analytical Chemistry
Publisher
Elsevier BV
Published
2018-08
Volume
105
Pages
453-469
ISSN
0165-9936 (ISSN-L)
OpenAlex
W2810965083
Cited by
486
References
277
Citations by year
2026: 40 · 2025: 59 · 2024: 67 · 2023: 65 · 2022: 71 · 2021: 90 · 2020: 58 · 2019: 31 · 2018: 3 · 2016: 1
FWCI
17.08
Type
journal article
Language
en
Open access
closed
Locations
  • TrAC Trends in Analytical Chemistry (publishedVersion)
  • Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
Funders
Melbourne Water
Topics
  • Physical Sciences › Environmental Science › Pollution › Pharmaceutical and Antibiotic Environmental Impacts
  • Physical Sciences › Environmental Science › Waste Management and Disposal › Wastewater Treatment and Reuse
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
Keywords
wastewater-based epidemiology, biomarkers, pharmaceuticals in wastewater, illicit drugs, tobacco, alcohol, industrial chemical exposure, infectious disease surveillance, pathogen detection, antibiotic resistance, microbial exposure, population health

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