Prevalence and triggers of syncope in medical students

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SYNCOPE IN A POPULATION OF HEALTHY YOUNG ADULTS

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Clinical characteristics of patients with vasovagal reactions presenting as unexplained syncope

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Guidelines for the diagnosis and management of syncope (version 2009): The Task Force for the Diagnosis and Management of Syncope of the European Society of Cardiology (ESC)

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2018 ESC Guidelines for the diagnosis and management of syncope

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Guidelines on Management (diagnosis and treatment) of syncope ? update 2004

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2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope

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2018 ESC Guidelines for the diagnosis and management of syncope

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2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society

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2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society

Shen, W.-K., Sheldon, R. S., Benditt, D. G., Cohen, M. I., Forman, D. E., Goldberger, Z. D., Grubb, B. P., Hamdan, M. H., Krahn, A. D., Link, M. S., et al. (2017) · Circulation · doi:10.1161/cir.0000000000000498 · Cited by 411

Lifetime cumulative incidence of syncope in the general population: a study of 549 Dutch subjects aged 35–60 years

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Initial orthostatic hypotension: review of a forgotten condition

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2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope

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Effectiveness of Physical Counterpressure Maneuvers in Preventing Vasovagal Syncope

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Epidemiology of reflex syncope

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Guía de práctica clínica para el diagnóstico y manejo del síncope (versión 2009)

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Sex differences and blood pressure regulation in humans

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Practical Instructions for the 2018 ESC Guidelines for the diagnosis and management of syncope

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Vasovagal syncope in medical students and their first-degree relatives

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Sex, ageing and resting blood pressure: gaining insights from the integrated balance of neural and haemodynamic factors

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Medical Student Experience in Surgery Influences Their Career Choices: A Systematic Review of the Literature

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South American Guidelines for Cardiovascular Disease Prevention and Rehabilitation

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Common Syndromes of Orthostatic Intolerance

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Syncope prevalence in the ED compared to general practice and population: a strong selection process

Olde Nordkamp, L. R. A., van Dijk, N., Ganzeboom, K. S., Reitsma, J. B., Luitse, J. S. K., Dekker, L. R. C., Shen, W.-K., & Wieling, W. (2009) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2008.02.022 · Cited by 158

Reflex syncope in children and adolescents

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A guide to disorders causing transient loss of consciousness: focus on syncope

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Age of First Faint in Patients with Vasovagal Syncope

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Epidemiology of Syncope/Collapse in Younger and Older Western Patient Populations

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Linking the hemodynamic consequences of adverse childhood experiences to an altered HPA axis and acute stress response

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Syncope in migraine: The population-based CAMERA study

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Clinical Factors Associated with Quality of Life in Patients with Transient Loss of Consciousness

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Neural Control of the Circulation: How Sex and Age Differences Interact in Humans

Joyner, M. J., Barnes, J. N., Hart, E. C., Wallin, B. G., & Charkoudian, N. (2014) · Comprehensive physiology · doi:10.1002/cphy.c140005 · Cited by 143

Autonomic uprising: the tilt table test in autonomic medicine

Cheshire, W. P., & Goldstein, D. S. (2019) · Clinical Autonomic Research · doi:10.1007/s10286-019-00598-9 · Cited by 130

Mechanisms of sympathetic regulation in orthostatic intolerance

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Influence of age and gender on the occurrence and presentation of reflex syncope

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Prevalence of Syncope in a Population Aged More Than 45 Years

Chen, L. Y., Shen, W.-K., Mahoney, D. W., Jacobsen, S. J., & Rodeheffer, R. J. (2006) · The American Journal of Medicine · doi:10.1016/j.amjmed.2006.01.029 · Cited by 111

Neurovascular control of blood pressure is influenced by aging, sex, and sex hormones

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The origin of vasovagal syncope: to protect the heart or to escape predation?

Alboni, P., Alboni, M., & Bertorelle, G. (2008) · Clinical Autonomic Research · doi:10.1007/s10286-008-0479-7 · Cited by 93

Syncope While Driving

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Is vasovagal syncope a disease?

Alboni, P., Brignole, M., & Uberti, E. C. D. (2007) · EP Europace · doi:10.1093/europace/eul179 · Cited by 81

Syncope in Brugada syndrome: prevalence, clinical significance, and clues from history taking to distinguish arrhythmic from nonarrhythmic causes

Olde Nordkamp, L. R. A., Vink, A. S., Wilde, A. A. M., de Lange, F. J., de Jong, J. S. S. G., Wieling, W., van Dijk, N., & Tan, H. L. (2015) · Heart Rhythm · doi:10.1016/j.hrthm.2014.10.014 · Cited by 80

The Second Prevention of Syncope Trial (POST II)—a randomized clinical trial of fludrocortisone for the prevention of neurally mediated syncope: Rationale and study design

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The consensus statement on the definition of orthostatic hypotension: a revisit after 13 years

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Value of history-taking in syncope patients: in whom to suspect long QT syndrome?

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The diagnostic protocol in children and adolescents with syncope: a multi‐centre prospective study

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Drugs and pacemakers for vasovagal, carotid sinus and situational syncope

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Diagnostic value of history taking in reflex syncope

Colman, N., Nahm, K., van Dijk, J. G., Reitsma, J. B., Wieling, W., & Kaufmann, H. (2004) · Clinical Autonomic Research · doi:10.1007/s10286-004-1006-0 · Cited by 65

Sex Differences in Cardiovascular Aging and Heart Failure

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Management and therapy of vasovagal syncope: A review

Aydin, M. A. (2010) · World Journal of Cardiology · doi:10.4330/wjc.v2.i10.308 · Cited by 63

Implantable loop recorder versus conventional diagnostic workup for unexplained recurrent syncope

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Exercise related syncope, when it?s not the heart

Krediet, C. T. P., Wilde, A. A. M., Wieling, W., & Halliwill, J. R. (2004) · Clinical Autonomic Research · doi:10.1007/s10286-004-1005-1 · Cited by 51

How to Differentiate Syncope from Seizure

Sheldon, R. S. (2015) · Cardiology Clinics · doi:10.1016/j.ccl.2015.04.006 · Cited by 49

The Prevalence and Cost of the Faint and Fall Problem in the State of Utah

Malasana, G., Brignole, M., Daccarett, M., Sherwood, R. P., & Hamdan, M. H. (2010) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2010.02930.x · Cited by 51

Postural syncope: mechanisms and management

Vaddadi, G., Lambert, É., Corcoran, S. J., & Esler, M. (2007) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.2007.tb01248.x · Cited by 49

Evidence-based treatment for vasovagal syncope

Kuriachan, V., Sheldon, R. S., & Platonov, M. (2008) · Heart Rhythm · doi:10.1016/j.hrthm.2008.08.023 · Cited by 47

Orthostatic intolerance and the headache patient

Mack, K. J., Johnson, J. N., & Rowe, P. C. (2010) · Seminars in Pediatric Neurology · doi:10.1016/j.spen.2010.04.006 · Cited by 47

The different clinical presentations of vasovagal syncope

Alboni, P. (2015) · Heart · doi:10.1136/heartjnl-2014-307096 · Cited by 46

Early and late-onset syncope: insight into mechanisms

Torabi, P., Rivasi, G., Hamrefors, V., Ungar, A., Sutton, R., Brignole, M., & Fedorowski, A. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehac017 · Cited by 46

Guanfacine Extended Release: A Novel Treatment for Attention-Deficit/Hyperactivity Disorder in Children and Adolescents

Faraone, S. V., McBurnett, K., Sallee, F. R., Steeber, J., & López, F. A. (2013) · Clinical Therapeutics · doi:10.1016/j.clinthera.2013.09.005 · Cited by 44

Identifying Cardiac Syncope Based on Clinical History: A Literature-Based Model Tested in Four Independent Datasets

Berecki-Gisolf, J., SHELDON, A. G., Wieling, W., van Dijk, N., Costantino, G., Furlan, R., Shen, W.-K., & Sheldon, R. S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0075255 · Cited by 44

Operating theatre related syncope in medical students: a cross sectional study

Jamjoom, A., Nikkar‐Esfahani, A., & Fitzgerald, J. (2009) · BMC Medical Education · doi:10.1186/1472-6920-9-14 · Cited by 43

Initial orthostatic hypotension in teenagers and young adults

van Wijnen, V. K., Harms, M. P. M., Go-Schön, I. K., Westerhof, B. E., Krediet, C. T. P., Stewart, J. M., & Wieling, W. (2016) · Clinical Autonomic Research · doi:10.1007/s10286-016-0382-6 · Cited by 41

Typical vasovagal syncope as a “defense mechanism” for the heart by contrasting sympathetic overactivity

Alboni, P., & Alboni, M. (2017) · Clinical Autonomic Research · doi:10.1007/s10286-017-0446-2 · Cited by 42

Orthostatic heart rate does not predict symptomatic burden in pediatric patients with chronic orthostatic intolerance

Boris, J. R., Huang, J. Y., & Bernadzikowski, T. (2019) · Clinical Autonomic Research · doi:10.1007/s10286-019-00622-y · Cited by 41

Symptoms Before Sudden Arrhythmic Death Syndrome: A Nationwide Study Among the Young in Denmark

Glinge, C., Jabbari, R., Risgaard, B., Lynge, T. H., Engstrøm, T., Albert, C. M., Haunsø, S., Winkel, B. G., & Tfelt‐Hansen, J. (2015) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.12674 · Cited by 41

Clinical history in management of suspected syncope: A powerful diagnostic tool

Sutton, R., van Dijk, N., & Wieling, W. (2014) · Cardiology Journal · doi:10.5603/cj.2014.0097 · Cited by 39

Regional Implementation of a Pediatric Cardiology Syncope Algorithm Using Standardized Clinical Assessment and Management Plans (SCAMPS) Methodology

Paris, Y. M., Toro-Salazar, O. H., Gauthier, N. S., Rotondo, K. M., Arnold, L., Hamershock, R. A., Saudek, D. E., Fulton, D. R., Renaud, A. M., & Alexander, M. E. (2016) · Journal of the American Heart Association · doi:10.1161/jaha.115.002931 · Cited by 39

Clinical Characteristics of Defecation and Micturition Syncope Compared with Common Vasovagal Syncope

Bae, M. H., Kang, J. K., Kim, N. Y., Choi, W. S., KIM, K. H., Park, S. H., Lee, J. H., Yang, D. H., Park, H. S., Cho, Y., et al. (2011) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2011.03290.x · Cited by 39

Update on the theory and management of orthostatic intolerance and related syndromes in adolescents and children

Stewart, J. M. (2012) · Expert Review of Cardiovascular Therapy · doi:10.1586/erc.12.139 · Cited by 38

Fear-related predictors of vasovagal symptoms during blood donation: it’s in the blood

Ditto, B., Gilchrist, P. T., & Holly, C. D. (2011) · Journal of Behavioral Medicine · doi:10.1007/s10865-011-9366-0 · Cited by 37

Symptoms and Signs Associated with Syncope in Young People with Primary Cardiac Arrhythmias

MacCormick, J. M., Crawford, J., Chung, S., Shelling, A. N., Evans, C.-A., Rees, M. I., Smith, W., Crozier, I., MCALISTER, H. F., & Skinner, J. R. (2011) · Heart Lung and Circulation · doi:10.1016/j.hlc.2011.04.036 · Cited by 36

Salt supplementation in the management of orthostatic intolerance: Vasovagal syncope and postural orthostatic tachycardia syndrome

Williams, E. L., Raj, S. R., Schondorf, R., Shen, W.-K., Wieling, W., & Claydon, V. E. (2021) · Autonomic Neuroscience · doi:10.1016/j.autneu.2021.102906 · Cited by 36

Comparison of the active standing test and head-up tilt test for diagnosis of syncope in childhood and adolescence

Matsushima, R., Tanaka, H., & Tamai, H. (2004) · Clinical Autonomic Research · doi:10.1007/s10286-004-0182-2 · Cited by 36

Inhibition of lung carcinoma cell growth by high density lipoprotein-associated ?-tocopheryl-succinate

Hrzenjak, A., Reicher, H., Wintersperger, A., Steinecker-Frohnwieser, B., Sedlmayr, P., Schmidt, H., Nakamura, T., Malle, E., & Sattler, W. (2004) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-004-4101-4 · Cited by 36

NT-pro-BNP for diagnostic and prognostic evaluation in patients hospitalized for syncope

Pfister, R., Hagemeister, J., Esser, S., Hellmich, M., Erdmann, E., & Schneider, C. A. (2012) · International Journal of Cardiology · doi:10.1016/j.ijcard.2010.10.013 · Cited by 35

Daily, weekly, monthly, and seasonal patterns in the occurrence of vasovagal syncope in an older population

van Dijk, N., Boer, M. C., Santo, T. D., Grovale, N., AERTS, A. J. J., Boersma, L. V. A., & Wieling, W. (2007) · EP Europace · doi:10.1093/europace/eum104 · Cited by 34

Tilt Training: Does It Have a Role in Preventing Vasovagal Syncope?

Gurevitz, O. T., Barsheshet, A., Bar-Lev, D. S., Zimlichman, E., Rosenfeld, G., Benderly, M., Luria, D. M., Amital, H., Kreiss, Y., Eldar, M., et al. (2007) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2007.00898.x · Cited by 33

Physical counter-pressure manoeuvres in preventing syncopal recurrence in patients older than 40 years with recurrent neurally mediated syncope: a controlled study from the Third International Study on Syncope of Uncertain Etiology (ISSUE-3)†

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Neural Control of the Circulation: How Sex and Age Differences Interact in Humans

Joyner, M. J., Barnes, J. N., Hart, E. C., Wallin, B. G., & Charkoudian, N. (2015) · Comprehensive physiology · doi:10.1002/j.2040-4603.2015.tb00598.x · Cited by 32

Gender Difference in Patients with Recurrent Neurally Mediated Syncope

Park, J., Jang, S. Y., Yim, H. R., On, Y. K., Huh, J., Shin, D., Kim, J. H., & Kim, J. S. (2010) · Yonsei Medical Journal · doi:10.3349/ymj.2010.51.4.499 · Cited by 34

Vasovagal Syncope As A Manifestation Of An Evolutionary Selected Trait.

Alboni, P., & Alboni, M. (2014) · PubMed Central · doi:10.4022/jafib.1035 · Cited by 31

Management of Syncope in Adults: An Update

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Head‐up tilt test provokes dynamic alterations in total peripheral resistance and cardiac output in children with vasovagal syncope

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Genetic aspects of vasovagal syncope: a systematic review of current evidence

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Investigation on the Incidence of Syncope in Children and Adolescents Aged 2–18 Years in Changsha

Hu, E., Liu, X., Chen, Q., & Wang, C. (2021) · Frontiers in Pediatrics · doi:10.3389/fped.2021.638394 · Cited by 28

Initial orthostatic hypotension and cerebral blood flow regulation: effect of α1-adrenoreceptor activity

Lewis, N. C. S., Ainslie, P. N., Atkinson, G., Jones, H., Grant, E. J. M., & Lucas, S. J. E. (2012) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00427.2012 · Cited by 28

Syncope in paced patients with sick sinus syndrome from the DANPACE trial: incidence, predictors and prognostic implication

Ng Kam Chuen, M. J., Kirkfeldt, R. E., Andersen, H. R., & Nielsen, J. C. (2014) · Heart · doi:10.1136/heartjnl-2013-304976 · Cited by 27

Postural Heart Rate Changes in Young Patients With Vasovagal Syncope

Medow, M. S., Merchant, S., Suggs, M., Terilli, C., O’Donnell-Smith, B., & Stewart, J. M. (2017) · Pediatrics · doi:10.1542/peds.2016-3189 · Cited by 27

ED management of pediatric syncope: searching for a rationale

Goble, M. M., Benitez, C., Baumgardner, M., & Fenske, K. (2008) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2007.06.012 · Cited by 26

Sex differences in the ventilatory and cardiovascular response to supine and tilted metaboreflex activation

Joshi, H., & Edgell, H. (2019) · Physiological Reports · doi:10.14814/phy2.14041 · Cited by 26

Predicting Recurrence of Vasovagal Syncope: A Simple Risk Score for the Clinical Routine

Aydin, M. A., Maas, R., Mortensen, K., Steinig, T., Klemm, H. U., Risius, T., Meinertz, T., Willems, S., Morillo, C. A., & Ventura, R. (2008) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2008.01352.x · Cited by 26

Cardiac Events During Competitive, Recreational, and Daily Activities in Children and Adolescents With Long QT Syndrome

Chambers, K. D., Ladouceur, V. B., Alexander, M. E., Hylind, R. J., Bevilacqua, L. M., Mah, D. Y., Bezzerides, V. J., Triedman, J. K., Walsh, E. P., & Abrams, D. J. (2017) · Journal of the American Heart Association · doi:10.1161/jaha.116.005445 · Cited by 25

The Role of Race, Sex, and Age in Circadian Disruption and Metabolic Disorders

Zhang, C., Tait, C., Minacapelli, C. D., Bhurwal, A., Gupta, K., Amin, R. N., & Rustgi, V. K. (2022) · Gastro Hep Advances · doi:10.1016/j.gastha.2022.02.015 · Cited by 27

Stress and the baroreflex

Norcliffe‐Kaufmann, L. (2022) · Autonomic Neuroscience · doi:10.1016/j.autneu.2022.102946 · Cited by 27

Autonomic Function in Children and Adolescents with Neurocardiogenic Syncope

Longin, E., Reinhard, J., von Buch, C., Gerstner, T., Lenz, T., & König, S. (2008) · Pediatric Cardiology · doi:10.1007/s00246-008-9198-z · Cited by 24

Vasovagal syncope in humans and protective reactions in animals

Blanc, J. J., Alboni, P., & Benditt, D. G. (2015) · EP Europace · doi:10.1093/europace/euu367 · Cited by 24

Syncope

Cheshire, W. P. (2017) · CONTINUUM Lifelong Learning in Neurology · doi:10.1212/con.0000000000000444 · Cited by 25

Norepinephrine transport inhibition for treatment of vasovagal syncope

SHELDON, R. S., RITCHIE, D., MCRAE, M., & RAJ, S. (2013) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.12111 · Cited by 22

Lower limb-localized vascular phenomena explain initial orthostatic hypotension upon standing from squat

Tschakovsky, M. E., Matusiak, K., Vipond, C., & McVicar, L. (2011) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00571.2011 · Cited by 22

Practice Variation and Resource Use in the Evaluation of Pediatric Vasovagal Syncope: Are Pediatric Cardiologists Over-Testing?

Johnson, E. R., Etheridge, S. P., Minich, L. L., Bardsley, T. R., Heywood, M. C., & Menon, S. C. (2013) · Pediatric Cardiology · doi:10.1007/s00246-013-0848-4 · Cited by 22

Role of yoga as an adjunctive therapy in patients with neurocardiogenic syncope: a pilot study

Gunda, S., Kanmanthareddy, A., Atkins, D., Bommana, S., Pimentel, R., Drisko, J., Biase, L. D., Beheiry, S., Hao, S. C., Natale, A., et al. (2015) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-015-9996-1 · Cited by 22

Are women really more affected by vasovagal syncope than men?

Alboni, P., Messop, A. C., Lauri, A., & Furlan, R. (2020) · Journal of Cardiovascular Medicine · doi:10.2459/jcm.0000000000001009 · Cited by 22

Pediatric Syncope: Cases from the Emergency Department

Fischer, J. W. J., & Cho, C. S. (2010) · Emergency Medicine Clinics of North America · doi:10.1016/j.emc.2010.03.009 · Cited by 22

Prevalence rate and triggering factors of syncope in medical students

Chang, B.-J., Ryu, H. M., Lee, J. H., Shin, J.-K., Kwon, Y., Lee, H.-S., Shin, S.-C., Kim, H., Heo, J.-H., Yang, D., et al. (2004) · The Korean Journal of Internal Medicine

Syncope and presyncope in adolescents: A single-center experience

Leep, P. W. (2018) · Journal of Clinical & Experimental Cardiology

Prevalence of self-reported syncope: an epidemiologic study from Olmsted County, MN

Chen, L. Y., Shen, W. K., Mahoney, D. W., Jacobsen, S. J., & Rodeheffer, R. J. (2002) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)80500-9 · Cited by 9

Syncope in medical practice.

ROUYER, J. (1957) · PubMed

Studies on syncope

van Dijk, N. (2006)