New insights into the role of cortisol and the glucocorticoid receptor in severe depression
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MDD is characterized by visceral, neuroendocrine, and autonomic disturbances that often lead to altered weight, appetite, and sleep.
“Visceral, neuroendocrine, and autonomic disturbances also characterize MDD, and they often lead to altered weight, appetite, and sleep (34).”
From Localization of Dysfunction in Major Depressive Disorder: Prefrontal Cortex and Amygdala (2011) · cites this paper as [34]
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- Authors
- Gold, P. W., Drevets, W. C., Charney, D. S., & Drevets, W. C.
- Affiliations
- National Institutes of Health (US)
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2002-09
- Volume
- 52
- Issue
- 5
- Pages
- 381-385
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W1992668905
- Cited by
- 219
- References
- 44
- Citations by year
- 2026: 2 · 2025: 2 · 2023: 2 · 2022: 2 · 2021: 5 · 2020: 2 · 2019: 3 · 2018: 2 · 2017: 7 · 2016: 3 · 2015: 7 · 2014: 5 · 2013: 12 · 2012: 8
- FWCI
- 7.56
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
- Keywords
- cortisol, glucocorticoid receptor, severe depression, psychotic depression, mifepristone, hypercortisolism, stress response, hypothalamic-pituitary-adrenal axis, mood disorders
- MeSH terms
- Amygdala, Antidepressive Agents, Depressive Disorder, Hippocampus, Humans, Hydrocortisone, Hypothalamus, Receptors, Glucocorticoid, Mifepristone, Prefrontal Cortex
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