Cited by 103Sesquiterpenes and Asteraceae StudiesOrganic Chemistry Synthesis MethodsBiological Activity of Diterpenoids and Biflavonoids

Stereoselective synthesis of artemisinin

Ravindranathan, T., Anil Kumar, M., Menon, Rani B., Hiremath, S.V.·1990·Tetrahedron Letters

Integrity signals

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Crossref · 10.1016/s0040-4039(00)94621-5

Cites

9 of 9 references verified0 citation errors · 0 not checkable

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  • Chemical synthesis of artemisinin is far too expensive for many in the Third World because of the structural complexity of the target and the large number of steps in published synthetic routes.

    “Although artemisinin can be produced by chemical synthesis [171,228,229,230,231,232,233,234,235,236,237,238,239], the structural complexity of this target and the large number of steps involved in all published synthetic routes render this approach far too expensive for many in the Third World who are most affected by malaria.”

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Authors
Ravindranathan, T., Anil Kumar, M., Menon, R. B., & Hiremath, S. V.
Affiliations
National Chemical Laboratory (IN)
Venue
Tetrahedron Letters
Publisher
Elsevier BV
Published
1990-01
Volume
31
Issue
5
Pages
755-758
ISSN
0040-4039 (ISSN-L)
OpenAlex
W1984047589
Cited by
103
References
9
Citations by year
2026: 1 · 2024: 2 · 2023: 2 · 2022: 1 · 2021: 3 · 2020: 3 · 2019: 3 · 2018: 3 · 2017: 3 · 2016: 2 · 2015: 1 · 2014: 4 · 2013: 4 · 2012: 5
FWCI
2.36
Type
journal article
Language
en
Open access
closed
Locations
Tetrahedron Letters (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Sesquiterpenes and Asteraceae Studies
  • Physical Sciences › Chemistry › Organic Chemistry › Organic Chemistry Synthesis Methods
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Biological Activity of Diterpenoids and Biflavonoids
Keywords
artemisinin, stereoselective synthesis, intramolecular Diels-Alder reaction, trienes, sesquiterpenes, total synthesis

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