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G M Shearer

doi:10.1016/s0047-6374(96)01849-0

Cited by 174Cerebrospinal fluid and hydrocephalusBarrier Structure and Function StudiesAdvanced MRI Techniques and Applications

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G M Shearer·1997·Mechanisms of Ageing and Development

DOI 10.1016/s0047-6374(96)01849-0

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Studies examining CD4+ T-helper cells in the context of ageing have traditionally shown that cells exhibiting a Th2 profile dominate over cells with a Th1 profile in the elderly.
“Studies examining CD4+ T-helper (Th) cells in the context of ageing, have traditionally shown, based on their signature cytokine profiles, that cells exhibiting a Th2 profile (i.e., IL-4 producing cells) dominate over cells with a Th1 profile (i.e., IFN-γ producing cells) in the elderly (Deng et al. 2004; Shearer 1997).”
From Is immunosenescence influenced by our lifetime “dose” of exercise? (2016) · cites this paper as Shearer 1997

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Authors: Shearer, G. M.
Affiliations: National Institutes of Health (US)
Corresponding author: G M Shearer
Venue: Mechanisms of Ageing and Development
Publisher: Elsevier BV
Published: 1997-03
Volume: 94
Issue: 1-3
Pages: 1-5
ISSN: 0047-6374 (ISSN-L)
DOI: 10.1016/s0047-6374(96)01849-0
OpenAlex: W143197739
Cited by: 174
References: 0
Citations by year: 2026: 3 · 2024: 1 · 2023: 1 · 2021: 6 · 2020: 4 · 2019: 5 · 2018: 3 · 2017: 10 · 2016: 7 · 2015: 2 · 2014: 7 · 2013: 10 · 2012: 5
FWCI: 2.60
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Mechanisms of Ageing and Development (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Cerebrospinal fluid and hydrocephalus
Life Sciences › Neuroscience › Neurology › Barrier Structure and Function Studies
Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
Keywords: blood-CSF barrier, choroid plexus epithelium, contrast-enhanced MRI, gadolinium enhancement, blood-CSF barrier permeability, age-related neurodegeneration, manganese contrast agent, cerebrospinal fluid homeostasis
MeSH terms: Aging, Animals, Humans, Cytokines, Th1 Cells, Th2 Cells

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