Cited by 362Neurotransmitter Receptor Influence on BehaviorNeurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

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New evidence for neurotransmitter influences on brain development

Levitt, Pat, Harvey, John A., Friedman, Eitan, Simansky, Kenny, Murphy, E.Hazel·1997·Trends in Neurosciences

DOI 10.1016/s0166-2236(96)01028-4

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Abstract

The early appearance of monoamine systems in the developing mammalian CNS suggests that they play a role in neural development. We review data from two model systems that provide compelling new evidence of this role. In one model system-in utero exposure to cocaine-specific and robust alterations are seen in dopamine-rich areas of the cerebral cortex, such as the anterior cingulate cortex: D1 receptor-G protein coupling is greatly reduced, the GABAergic system is altered and pyramidal dendrites undergo excessive growth. In a second model system-a transgenic mouse line in which the gene that encodes monoamine oxidase A (MAOA) is disrupted, resulting in excessively high 5-HT levels-barrels fail to form in the developing somatosensory cortex. Both models reveal the effects of very early manipulation of monoamines on forebrain development, and the long-term anomalies that persist into adulthood.

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The Cognitive neurosciences
(2005) · Choice Reviews Online · doi:10.5860/choice.43-0626 · Cited by 4,726
Psychopharmacology: The third generation of progress
O’Connell, R. A. (1988) · Comprehensive Psychiatry · doi:10.1016/0010-440x(88)90057-0 · Cited by 3,020
Drugs of abuse: anatomy, pharmacology and function of reward pathways
Koob, G. F. (1992) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(92)90060-j · Cited by 2,070
Psychopharmacology: The Third Generation of Progress.
(1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-108-3-509_2 · Cited by 2,021
Autoradiographic Study of Cell Migration during Histogenesis of Cerebral Cortex in the Mouse
ANGEVINE, J. B., & SIDMAN, R. L. (1961) · Nature · doi:10.1038/192766b0 · Cited by 1,530
Neuronal migration, with special reference to developing human brain: a review
Sidman, R. L., & RAKIC, P. T. (1973) · Brain Research · doi:10.1016/0006-8993(73)90617-3 · Cited by 1,260
Aggressive Behavior and Altered Amounts of Brain Serotonin and Norepinephrine in Mice Lacking MAOA
Cases, O., Seif, I., Grimsby, J. S., Gaspar, P., Chen, K., Vandormael‐Pournin, S., Müller, U., Aguet, M., Babinet, C., Shih, J. C., et al. (1995) · Science · doi:10.1126/science.7792602 · Cited by 1,225
Neurons in Rhesus Monkey Visual Cortex: Systematic Relation between Time of Origin and Eventual Disposition
Rakic, P. (1974) · Science · doi:10.1126/science.183.4123.425 · Cited by 1,161
Advances in infancy research
Lipsitt, L. P., & Rovee‐Collier, C. (1981) · Ablex Publishing Corp. eBooks · Cited by 1,146
Central Catecholamine Neuron Systems: Anatomy and Physiology of the Norepinephrine and Epinephrine Systems
Moore, R. Y., & Bloom, F. E. (1979) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.02.030179.000553 · Cited by 1,118

Show all 86 references

Research works printed but not linked: 13

Olsen, 1995, Neurotoxicology, 16, 159
Spear, 1995, Vol. 9, 55
Seidler, 1992, J. Pharmacol. Exp. Ther., 263, 413
Battaglia, 1995, NIDA Res. Monogr. Ser., 158, 115
Lidow, 1994, Soc. Neurosci. Abstr., 20, 596
Murphy, 1995, Lab. Anim. Sci., 45, 163
Breslin, N.A. and Weinberger, D.R. (1991) in Fetal Neural Development and Adult Schizophrenia (Mednick, S.A. et al., eds), pp. pp. 199–215, Cambridge University Press
Wang, 1997, Exp. Brain Res., 112, 359
Murphy, E.H. et al. Exp. Brain Res. (in press)
Wang, 1995, J. Pharmacol. Exp. Ther., 273, 492
Grayson, 1941, Soc. Neurosci. Abstr., 22
Wang, 1996, Brain Res., 715, 221, 10.1016/0006-8993(96)00012-1 · DOI
Goldberg, 1989, Dev. Biol., 141, 438

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Authors: Levitt, P., Harvey, J. A., Friedman, E., Simansky, K., & Murphy, E. H.
Affiliations: University of Pittsburgh (US)
ORCID: Levitt, Pat
Friedman, Eitan
Venue: Trends in Neurosciences
Publisher: Elsevier BV
Published: 1997-06
Volume: 20
Issue: 6
Pages: 269-274
ISSN: 0166-2236 (ISSN-L)
DOI: 10.1016/s0166-2236(96)01028-4
OpenAlex: W2167345246
Cited by: 362
References: 86
Citations by year: 2026: 4 · 2025: 3 · 2024: 7 · 2023: 2 · 2022: 9 · 2021: 4 · 2020: 4 · 2019: 6 · 2018: 4 · 2017: 5 · 2016: 7 · 2015: 6 · 2014: 5 · 2013: 11 · 2012: 11
FWCI: 2.58
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Trends in Neurosciences (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5p01da006871-04)
National Institute on Drug Abuse (P01DA06871)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords: monoaminergic systems, brain development, dopamine, dopamine D1 receptor, G protein coupling, GABAergic system, anterior cingulate cortex, monoamine oxidase A, serotonin, somatosensory cortex, transgenic mice, forebrain development, developmental neurotoxicity
MeSH terms: Animals, Brain, Cocaine, Female, Mice, Transgenic, Pregnancy, Prenatal Exposure Delayed Effects, Neurotransmitter Agents, Mice

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New evidence for neurotransmitter influences on brain development

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