The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Innate immunity: impact on the adaptive immune response
Open accessAbstract
For many years, innate immunity has been considered as a separate entity from the adaptive immune response and has been regarded to be of secondary importance in the hierarchy of immune functions. For the past few years, however, interest in innate immunity has grown enormously, so that now it is studied intensively in many laboratories that seek to integrate these two distinct types of immune function. Our intent in this review is to point out the similarities and differences in these two types of host response to infection, and to indicate our present level of understanding of how these can be integrated into a more complete description of the immune response.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
CpG motifs in bacterial DNA trigger direct B-cell activation
Krieg, A. M., Yi, A.-K., Matson, S., Waldschmidt, T. J., Bishop, G. A., Teasdale, R., Koretzky, G. A., & Klinman, D. M. (1995) · Nature · doi:10.1038/374546a0 · Cited by 3,508
Receptor-Dependent Mechanisms of Cell Stimulation by Bacterial Endotoxin
Ulevitch, R. J., & Tobias, P. S. (1995) · Annual Review of Immunology · doi:10.1146/annurev.iy.13.040195.002253 · Cited by 1,442
Cited by
Janeway, C. A., & Medzhitov, R. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.083001.084359 · Cited by 8,394
Self-citationC-Reactive Protein, Interleukin 6, and Risk of Developing Type 2 Diabetes Mellitus
Pradhan, A. D. (2001) · JAMA · doi:10.1001/jama.286.3.327 · Cited by 4,433
Toll-like receptors and innate immunity
Medzhitov, R. (2001) · Nature Reviews Immunology · doi:10.1038/35100529 · Cited by 4,308
Self-citationInnate Immunity: The Virtues of a Nonclonal System of Recognition
Medzhitov, R., & Janeway, C. A. (1997) · Cell · doi:10.1016/s0092-8674(00)80412-2 · Cited by 2,434
“None of these compounds are produced review, see Janeway, 1989; Fearon and Locksley, 1996; by the host organism, and all of them are essential for Medzhitov and Janeway, 1997).”
BackgroundSelf-citationThe Inflammasomes: Guardians of the Body
Martinon, F., Mayor, A., & Tschopp, J. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132715 · Cited by 2,436
Delves, P. J., & Roitt, I. M. (2000) · New England Journal of Medicine · doi:10.1056/nejm200007063430107 · Cited by 1,666
Novel Signal Transduction Pathway Utilized by Extracellular HSP70
Asea, A., Rehli, M., Kabingu, E., Boch, J. A., Baré, O., Auron, P. E., Stevenson, M. A., & Calderwood, S. K. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m200497200 · Cited by 1,510
Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs
Olson, J. K., & Miller, S. D. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.6.3916 · Cited by 1,215
Lehnardt, S., Massillon, L., Follett, P., Jensen, F. E., Ratan, R., Rosenberg, P. A., Volpe, J. J., & Vartanian, T. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1432609100 · Cited by 1,052
Insulin Resistance and Chronic Cardiovascular Inflammatory Syndrome
Fernández-Real, J. M., & Ricart, W. (2003) · Endocrine Reviews · doi:10.1210/er.2002-0010 · Cited by 886
Alternative macrophage activation and metabolism
Odegaard, J. I., & Chawla, A. (2011) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathol-011110-130138 · Cited by 640
Yang, D., Biragyn, A., Hoover, D. M., Lubkowski, J., & Oppenheim, J. J. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.22.012703.104603 · Cited by 572
Vagal immune-to-brain communication: a visceral chemosensory pathway
Goehler, L. E., Gaykema, R. P. A., Hansen, M. K., Anderson, K., Maier, S. F., & Watkins, L. R. (2000) · Autonomic Neuroscience · doi:10.1016/s1566-0702(00)00219-8 · Cited by 525
Black, P. H. (2003) · Brain Behavior and Immunity · doi:10.1016/s0889-1591(03)00048-5 · Cited by 502
A Recent Perspective on Alcohol, Immunity, and Host Defense
Szabo, G., & Mandrekar, P. (2009) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00842.x · Cited by 387
An ancient system of host defense
Medzhitov, R., & Janeway, C. A. (1998) · Current Opinion in Immunology · doi:10.1016/s0952-7915(98)80024-1 · Cited by 327
Self-citationA trio of microRNAs that control Toll-like receptor signalling
Quinn, S. R., & O'Neill, L. A. (2011) · International Immunology · doi:10.1093/intimm/dxr034 · Cited by 314
Barrila, J., Radtke, A. L., Crabbé, A., Sarker, S. F., Herbst-Kralovetz, M. M., Ott, C. M., & Nickerson, C. A. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2423 · Cited by 302
Iron-withholding strategy in innate immunity
Ong, S. T., Shan Ho, J. Z., Ho, B., & Ding, J. L. (2006) · Immunobiology · doi:10.1016/j.imbio.2006.02.004 · Cited by 269
Macrophage and dendritic cell phenotypic diversity in the context of biomaterials
Kou, P. M., & Babensee, J. E. (2011) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32971 · Cited by 190
Olson, J. K., Girvin, A. M., & Miller, S. D. (2001) · Journal of Virology · doi:10.1128/jvi.75.20.9780-9789.2001 · Cited by 178
Glucocorticoid sensitivity in humans-interindividual differences and acute stress effects
Rohleder, N., Wolf, J. M., & Kirschbaum, C. (2003) · Stress · doi:10.1080/1025389031000153658 · Cited by 118
Miyake, T., Kumagai, Y., Kato, H., Guo, Z., Matsushita, K., Satoh, T., Kawagoe, T., Kumar, H., Jang, M. H., Kawai, T., et al. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0901500 · Cited by 115
TCRdb: a comprehensive database for T-cell receptor sequences with powerful search function
Chen, S.-Y., Yue, T., Lei, Q., & Guo, A.-Y. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkaa796 · Cited by 106
CCL1 released from M2b macrophages is essentially required for the maintenance of their properties
Asai, A., Nakamura, K., Kobayashi, M., Herndon, D. N., & Suzuki, F. (2012) · Journal of Leukocyte Biology · doi:10.1189/jlb.0212107 · Cited by 54
Neuroimmunoregulation and natural immunity
Berczi, I., Chow, D. A., & Sabbadini, E. R. (1998) · Domestic Animal Endocrinology · doi:10.1016/s0739-7240(98)00015-0 · Cited by 43
Kook, S.-Y., Chung, E.-C., Lee, Y., Lee, D. W., & Kim, S. (2019) · PLOS ONE · doi:10.1371/journal.pone.0223913 · Cited by 41
Li, Y., Heuser, J. S., Kosanke, S. D., Hemric, M., & Cunningham, M. W. (2005) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)62948-3 · Cited by 39
Dangerous Allergens: Why Some Allergens are Bad Actors
Georas, S. N., Rezaee, F., Lerner, L., & Beck, L. (2010) · Current Allergy and Asthma Reports · doi:10.1007/s11882-010-0090-6 · Cited by 16
Metadata
- Authors
- Medzhitov, R., & Janeway, C. A.
- Venue
- Current Opinion in Immunology
- Publisher
- Elsevier BV
- Published
- 1997-02
- Volume
- 9
- Issue
- 1
- Pages
- 4-9
- ISSN
- 0952-7915 (ISSN-L)
- OpenAlex
- W2057618822
- Cited by
- 1,558
- References
- 2
- FWCI
- 3.66
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
