Puberty and the emergence of gender differences in psychopathology
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Post-pubertal, pre-menopausal women are at much higher risk for PTSD and depression, and intact female rats are more sensitive to stress-induced PFC dysfunction than male rats or ovariectomized females.
“Interestingly, post-pubertal, pre-menopausal women are at much higher risk for PTSD and depression148, and intact female rats (that is, rats with normal oestrogen levels) are more sensitive to stress-induced PFC dysfunction than are male rats or ovariectomized females34,149.”
From Stress signalling pathways that impair prefrontal cortex structure and function (2009) · cites this paper as [148]
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- Authors
- Hayward, C., & Sanborn, K.
- Affiliations
- Stanford University (US)
- Stanford Medicine (US)
- Corresponding author
- Hayward, Chris
- Venue
- Journal of Adolescent Health
- Publisher
- Elsevier BV
- Published
- 2002-04
- Volume
- 30
- Issue
- 4
- Pages
- 49-58
- ISSN
- 1054-139X (ISSN-L)
- OpenAlex
- W2000219660
- Cited by
- 270
- References
- 99
- Citations by year
- 2026: 8 · 2025: 11 · 2024: 9 · 2023: 11 · 2022: 10 · 2021: 11 · 2020: 12 · 2019: 19 · 2018: 6 · 2017: 9 · 2016: 11 · 2015: 15 · 2014: 16 · 2013: 25 · 2012: 14
- FWCI
- 0.86
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Adolescent Health (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01mh045431-05, 5r01hd024779-06)
- National Institute of Mental Health (5 R01 MH45431-04)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (5 R01 HD24779-05)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Social Sciences › Psychology › Clinical Psychology › Psychology and Mental Health
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Keywords
- puberty, gender differences, internalizing disorders, depression, anxiety, eating disorders, adolescent girls, pubertal timing, sex hormones, victimization, peer relationships, developmental psychopathology
- MeSH terms
- Adolescent, Adolescent Behavior, Anxiety, Feeding and Eating Disorders, Depression, Female, Humans, Male, Puberty, Risk Factors, Sex Factors
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