Cited by 4,384COVID-19 and healthcare impactsCOVID-19 Clinical Research StudiesCOVID-19 Impact on Reproduction

Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China

Open access
Liang, Wenhua, Guan, Weijie, Chen, Ruchong, Wang, Wei, Li, Jianfu, Xu, Ke, Li, Caichen, Ai, Qing +4 more·2020·The Lancet Oncology

Integrity signals

Registry

Crossref · 10.1016/s1470-2045(20)30096-6

Cites

15 of 15 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Claims the paper makes

0 of 5 cited sources checked · 0 supported · 0 flagged

  • Findingown data
    § Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China

    Among the risk factors examined, a cancer history carried the strongest association with severe events.

    “Cancer history represented the highest risk for severe events (appendix p 3).”
    Quote in the paperSubstantial claim
  • Findingown data
    § Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China

    Cancer patients showed a greater risk of severe events-defined as ICU admission with invasive ventilation or death-than non-cancer patients (7/18 [39%] vs 124/1572 [8%]; Fisher's exact p=0.0003).

    “patients with cancer were observed to have a higher risk of severe events (a composite endpoint defined as the percentage of patients being admitted to the intensive care unit requiring invasive ventilation, or death) compared with patients without cancer (seven [39%] of 18 patients vs 124 [8%] of 1572 patients; Fisher's exact p=0·0003).”
    Quote in the paperSubstantial claim
  • Findingown data
    § Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China

    Lung cancer was not associated with a greater probability of severe events than other cancer types (1/5 [20%] vs 8/13 [62%]; p=0.294).

    “Patients with lung cancer did not have a higher probability of severe events compared with patients with other cancer types (one [20%] of five patients with lung cancer vs eight [62%] of 13 patients with other types of cancer; p=0·294).”
    Quote in the paperNot a substantial claim
  • Findingown data
    § Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China

    A smoking history was more common among cancer patients (4/18 [22%] vs 107/1572 [7%]).

    “more likely to have a history of smoking (four [22%] of 18 patients vs 107 [7%] of 1572 patients)”
    Quote in the paperNot a substantial claim
  • Findingown data
    § Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China

    Cancer patients had more polypnea (8/17 [47%] vs 323/1377 [23%]).

    “had more polypnea (eight [47%] of 17 patients vs 323 [23%] of 1377 patients; some data were missing on polypnea)”
    Quote in the paperNot a substantial claim
  • May combine two claims. 3
  • Classified as probably not a substantial claim. 1
  • May combine two claims.

    Findingown data
    § Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China

    Sex, other baseline symptoms, other comorbidities, and baseline x-ray severity did not differ significantly between the two groups.

    “but had no significant differences in sex, other baseline symptoms, other comorbidities, or baseline severity of x-ray (appendix p 2).”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data
    § Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China

    Of 16 cancer patients whose treatment status was known, four (25%) had undergone chemotherapy or surgery in the previous month, while the other 12 were survivors in routine follow-up after primary resection.

    “Four (25%) of 16 patients (two of the 18 patients had unknown treatment status) with cancer with COVID-19 had received chemotherapy or surgery within the past month, and the other 12 (25%) patients were cancer survivors in routine follow-up after primary resection.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductown data
    § Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China

    The analysis excluded 417 cases owing to incomplete records of prior disease history.

    “We excluded 417 cases because of insufficient records of previous disease history.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Study design and conductown data
    § Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China

    Every case had laboratory-confirmed COVID-19 acute respiratory disease and had been admitted to hospital.

    “All cases were diagnosed with laboratory-confirmed COVID-19 acute respiratory disease and were admitted to hospital.”
    Quote in the paperSubstantial claim
4 of 4
  • The paper relies on this without support.

    The 2015 cancer incidence in the overall Chinese population is a valid comparator for the proportion of cancer history among COVID-19 cases in the 2020 cohort.

    “which seems to be higher than the incidence of cancer in the overall Chinese population (285·83 [0·29%] per 100 000 people, according to 2015 cancer epidemiology statistics9)”
1 of 1

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Cancer survivors with COVID-19 face higher risk of ICU admission, ventilator use, or death compared to noncancer patients with COVID-19.

    “Survivors presenting with COVID-19 face a higher risk of being admitted to an ICU, being placed on a ventilator, or dying compared to noncancer patients with COVID-19.6”

    From Cancer during a pandemic: A psychosocial telehealth intervention for young adults (2022) · cites this paper as [6]

    The main text reports more severe events—a composite of ICU admission requiring invasive ventilation or death—among patients with cancer than among patients without cancer (39% versus 8%). It identifies 12 participants as cancer survivors, and the figure caption includes survivors, but the reported risk comparison is for the cancer group as a whole, not survivors specifically. No page number is provided in our copy. (LLM, conf=0.82)

    Experimental — accuracy not yet measured
  • Cancer patients are at higher risk of death or complications due to their systemic immunosuppressive state caused by the disease and its drug treatment.

    “Self-isolation was extremely important, especially for cancer patients, as they are a group at higher risk of death or complications due to their systemic immunosuppressive state caused by the disease and its drug treatment [27].”

    From The Effect of Vinyasa Yoga Practice on the Well-Being of Breast-Cancer Patients during COVID-19 Pandemic (2023) · cites this paper as [27]

    The opening paragraph attributes cancer patients’ immunosuppression to malignancy and anticancer treatment, then suggests they might have a poorer COVID-19 prognosis. The results report more severe events, including intensive-care admission, invasive ventilation, or death, among patients with cancer. The paper does not establish that immunosuppression caused those worse outcomes, as the citing sentence states. (LLM, conf=0.84)

    Experimental — accuracy not yet measured
  • Older adults diagnosed with both cancer and COVID-19 face increased mortality, hospitalization, and ICU admission.

    “Older adults diagnosed with both cancer and COVID-19 face increased mortality, hospitalization, and ICU admission [3,4,5].”

    From The Psychosocial Impact of COVID-19 on Older Adults with Cancer: A Rapid Review (2022) · cites this paper as [3]

    The results report more severe events—a composite of ICU admission requiring invasive ventilation or death—among patients with cancer than those without cancer. They also identify older age as a possible risk factor within the cancer group, but the estimate was not statistically significant (p=0.072). The methods state that all analyzed patients were admitted to hospital, so this study does not establish an increased risk of hospitalization. (LLM, conf=0.88)

    Experimental — accuracy not yet measured
  • Older adults with cancer may be among the most vulnerable to the effects of COVID-19 due to their immunocompromised status and increased presence of comorbidities.

    “This is particularly true of older adults with cancer, who may be among the most vulnerable to the effects of COVID-19 due to their immunocompromised status and increased presence of comorbidities [1,2,3,4,5].”

    From The Psychosocial Impact of COVID-19 on Older Adults with Cancer: A Rapid Review (2022) · cites this paper as [3]

    The introduction says cancer and its treatments can cause systemic immunosuppression, and the results report more severe COVID-19 outcomes in patients with cancer. The discussion calls for particular attention to older patients and those with other comorbidities. But the results say patients with cancer did not differ significantly from those without cancer in other comorbidities, so this paper does not support the claim that they had an increased presence of comorbidities. (LLM, conf=0.88)

    Experimental — accuracy not yet measured
  • Oncology patients are at high risk of contracting COVID-19 and suffering its complications, making prevention of acute healthcare utilization increasingly important during the pandemic.

    “Due to the high risk for contracting and suffering complications of COVID-19 among oncology patients, prevention of acute healthcare utilization, such as emergency room (ER) visits and hospitalizations, is increasingly important during the COVID-19 pandemic [1, 2].”

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

Each contradiction between two passages listed here was confirmed by an independent check.

  • Cancer-survivor percentage is incorrect

    Minor

    The 12 cancer survivors are described as part of the 16 patients with known treatment status. Twelve of 16 is 75%, not 25%.

    Reported 25 · recomputed 75

  • Unknown treatment status is counted as no recent treatment

    Minor

    The paper says treatment status was unknown for two patients, leaving 12 of the 18 outside the recently treated group with known status. It later describes 14 patients as not having received treatment, apparently placing the two with unknown status in that comparison group.

2 of 2

Cites

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1 of the 16 references couldn’t be matched to a known paper.

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Authors
Liang, W., Guan, W., Chen, R., Wang, W., Li, J., Xu, K., Li, C., Ai, Q., Lu, W., Liang, H., Li, S., & He, J.
Affiliations
First Affiliated Hospital of Guangzhou Medical University (CN)
Corresponding author
He, Jianxing
Venue
The Lancet Oncology
Publisher
Elsevier BV
Published
2020-03
Volume
21
Issue
3
Pages
335-337
ISSN
1470-2045 (ISSN-L)
OpenAlex
W3006355661
Cited by
4,384
References
16
Citations by year
2026: 33 · 2025: 77 · 2024: 204 · 2023: 392 · 2022: 647 · 2021: 1106 · 2020: 1908 · 2019: 8 · 2017: 1
FWCI
358.12
Type
journal article
Language
en
Open access
Locations
  • The Lancet Oncology (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • China National Science Foundation (81871893)
  • Key Project of Guangzhou Scientific Research (201804020030)
Topics
  • Health Sciences › Medicine › Oncology › COVID-19 and healthcare impacts
  • Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
  • Health Sciences › Medicine › Obstetrics and Gynecology › COVID-19 Impact on Reproduction
Keywords
COVID-19 pandemic, SARS-CoV-2, cancer patients, cancer survivors, COVID-19 mortality, multiple organ failure, angiotensin-converting enzyme 2, cancer care during pandemic
MeSH terms
Betacoronavirus, COVID-19, SARS-CoV-2, Age Factors, Aged, Aged, 80 and over, China, Humans, Medical History Taking, Middle Aged, Neoplasms, Pneumonia, Viral, Prognosis, Prospective Studies, Respiration, Artificial, Risk Factors, Severity of Illness Index, Coronavirus Infections

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Claims read by deepseek-v4.1-flash under definition version 3 (extract-v3) on 2026-09-30.

Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-09-30.

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