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Densely Isolated FeN4 Sites for Peroxidase Mimicking
Abstract
Despite the breakthroughs of transition-metal catalysts in enzyme mimicking, fundamental investigation on the design of efficient nanozymes at the atomic scale is still required for boosting their intrinsic activities to fill in gaps from enzymes to nanozymes. Herein, we developed a universal salt-template strategy for the fabrication of atomically dispersed Fe atoms on ultrathin nitrogen-doped carbon nanosheets characterized by a dramatically high concentration of 13.5 wt %. The proposed Fe-N-C nanozymes with densely isolated FeN 4 sites show high peroxidase-like activities and exhibit a specific activity of 25.33 U/mg, superior to Zn(Co)-N-C nanozymes. Both experiments and theoretical analysis revealed that FeN 4 sites not only lead to the strong adsorption of H 2 O 2 molecules but also weaken the bonding interaction between single Fe atom and two absorbed hydroxyl groups, lowering the energy barrier of the formation of hydroxyl radicals and therefore boosting their peroxidase-like activities. As expected, utilizing the peroxidase-like activity of Fe-N-C nanozymes, good sensitivity and selectivity for the intracellular H 2 O 2 monitoring were realized. It offers a versatile approach for the construction of densely isolated M-N-C single-atom catalysts and achieves better understanding of single sites for the peroxidase-like catalytic mechanisms.
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Citations
Cites
Heterogeneous single-atom catalysis
Wang, A., Li, J., & Zhang, T. (2018) · Nature Reviews Chemistry · doi:10.1038/s41570-018-0010-1 · Cited by 4,191
Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes
Wei, H., & Wang, E. (2013) · Chemical Society Reviews · doi:10.1039/c3cs35486e · Cited by 3,779
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
Huang, Y., Ren, J., & Qu, X. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00672 · Cited by 3,523
Single-Atom Catalysts: Synthetic Strategies and Electrochemical Applications
Chen, Y., Ji, S., Chen, C., Peng, Q., Wang, D., & Li, Y. (2018) · Joule · doi:10.1016/j.joule.2018.06.019 · Cited by 2,258
Self-citationNanozyme: new horizons for responsive biomedical applications
Jiang, D., Ni, D., Rosenkrans, Z. T., Huang, P., Yan, X., & Cai, W. (2019) · Chemical Society Reviews · doi:10.1039/c8cs00718g · Cited by 1,793
Nanozymes: From New Concepts, Mechanisms, and Standards to Applications
Liang, M., & Yan, X. (2019) · Accounts of Chemical Research · doi:10.1021/acs.accounts.9b00140 · Cited by 1,691
Kitchin, J. R., Nørskov, J. K., Barteau, M. A., & Chen, J. G. (2004) · The Journal of Chemical Physics · doi:10.1063/1.1737365 · Cited by 1,358
Standardized assays for determining the catalytic activity and kinetics of peroxidase-like nanozymes
Jiang, B., Duan, D., Gao, L., Zhou, M., Fan, K., Tang, Y., Xi, J., Bi, Y., Tong, Z., Gao, G. F., et al. (2018) · Nature Protocols · doi:10.1038/s41596-018-0001-1 · Cited by 1,300
Pharmacological potential of cerium oxide nanoparticles
Celardo, I., Pedersen, J. Z., Traversa, E., & Ghibelli, L. (2011) · Nanoscale · doi:10.1039/c0nr00875c · Cited by 1,151
In vivo guiding nitrogen-doped carbon nanozyme for tumor catalytic therapy
Fan, K., Xi, J., Fan, L., Wang, P., Zhu, C., Tang, Y., Xu, X., Liang, M., Jiang, B., Yan, X., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-03903-8 · Cited by 1,058
Self-citationHuang, L., Chen, J., Gan, L., Wang, J., & Dong, S. (2019) · Science Advances · doi:10.1126/sciadv.aav5490 · Cited by 993
Self-citationDirect transformation of bulk copper into copper single sites via emitting and trapping of atoms
Qu, Y., Li, Z., Chen, W., Lin, Y., Yuan, T., Yang, Z., Zhao, C., Wang, J., Zhao, C., Wang, X., et al. (2018) · Nature Catalysis · doi:10.1038/s41929-018-0146-x · Cited by 988
Self-citationChen, Y., Ji, S., Zhao, S., Chen, W., Dong, J., Cheong, W.-C., Shen, R., Wen, X., Zheng, L., Rykov, A. I., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-07850-2 · Cited by 977
Self-citationLiu, X., Jiao, Y., Zheng, Y., Jaroniec, M., & Qiao, S.-Z. (2019) · Journal of the American Chemical Society · doi:10.1021/jacs.9b03811 · Cited by 902
Zhao, L., Zhang, Y., Huang, L.-B., Liu, X.-Z., Zhang, Q.-H., He, C., Wu, Z.-Y., Zhang, L.-J., Wu, J., Yang, W., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-09290-y · Cited by 865
Self-citationA Single‐Atom Nanozyme for Wound Disinfection Applications
Xu, B., Wang, H., Wang, W., Gao, L., Li, S., Pan, X., Wang, H., Yang, H., Meng, X., Wu, Q., et al. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201813994 · Cited by 860
Reversible and cooperative photoactivation of single-atom Cu/TiO2 photocatalysts
Lee, B.-H., Park, S., Kim, M., Sinha, A. K., Lee, S. C., Jung, E., Chang, W. J., Lee, K.-S., Kim, J. H., Cho, S.-P., et al. (2019) · Nature Materials · doi:10.1038/s41563-019-0344-1 · Cited by 764
When Nanozymes Meet Single‐Atom Catalysis
Jiao, L., Yan, H., Wu, Y., Gu, W., Zhu, C., Du, D., & Lin, Y. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.201905645 · Cited by 700
Self-citationZhu, C., Shi, Q., Xu, B. Z., Fu, S., Wan, G., Yang, C., Yao, S., Song, J., Zhou, H., Du, D., et al. (2018) · Advanced Energy Materials · doi:10.1002/aenm.201801956 · Cited by 658
Self-citationCarbon Nanozymes: Enzymatic Properties, Catalytic Mechanism, and Applications
Sun, H., Zhou, Y., Ren, J., & Qu, X. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201712469 · Cited by 648
Non defect-stabilized thermally stable single-atom catalyst
Lang, R., Xi, W., Liu, J.-C., Cui, Y.-T., Li, T., Lee, A. F., Chen, F., Chen, Y., Li, L., Li, L., et al. (2019) · Nature Communications · doi:10.1038/s41467-018-08136-3 · Cited by 642
Self-citationPt/Cu single-atom alloys as coke-resistant catalysts for efficient C–H activation
Marcinkowski, M. D., Darby, M. T., Liu, J., Wimble, J. M., Lucci, F. R., Lee, S., Michaelides, A., Flytzani-Stephanopoulos, M., Stamatakis, M., & Sykes, E. C. H. (2018) · Nature Chemistry · doi:10.1038/nchem.2915 · Cited by 638
Yang, Q., Yang, C., Lin, C., & Jiang, H. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201813494 · Cited by 624
Cheng, Y., Zhao, S., Johannessen, B., Veder, J., Saunders, M., Rowles, M. R., Cheng, M., Liu, C., Chisholm, M. F., De Marco, R., et al. (2018) · Advanced Materials · doi:10.1002/adma.201706287 · Cited by 614
Highly Active and Stable Single-Atom Cu Catalysts Supported by a Metal–Organic Framework
Abdel-Mageed, A. M., Rungtaweevoranit, B., Parlinska-Wojtan, M., Pei, X., Yaghi, O. M., & Behm, R. J. (2019) · Journal of the American Chemical Society · doi:10.1021/jacs.8b11386 · Cited by 542
Xiao, M., Zhu, J., Ma, L., Jin, Z., Ge, J., Deng, X., Hou, Y., He, Q., Li, J., Jia, Q., et al. (2018) · ACS Catalysis · doi:10.1021/acscatal.8b00138 · Cited by 540
Yang, Z., Zhao, C., Qu, Y., Zhou, H., Zhou, F., Wang, J., Wu, Y., & Li, Y. (2019) · Advanced Materials · doi:10.1002/adma.201808043 · Cited by 429
Self-citationShen, R., Chen, W., Peng, Q., Lu, S., Zheng, L., Cao, X., Wang, Y., Zhu, W., Zhang, J., Zhuang, Z., et al. (2019) · Chem · doi:10.1016/j.chempr.2019.04.024 · Cited by 418
Zhang, Y., Wu, C., Jiang, H., Lin, Y., Liu, H., He, Q., Chen, S., Duan, T., & Song, L. (2018) · Advanced Materials · doi:10.1002/adma.201707522 · Cited by 377
Self-citationNanocatalytic Tumor Therapy by Single-Atom Catalysts
Huo, M., Wang, L., Wang, Y., Chen, Y., & Shi, J. (2019) · ACS Nano · doi:10.1021/acsnano.9b00457 · Cited by 368
Self-citationFe–N–C Single-Atom Nanozymes for the Intracellular Hydrogen Peroxide Detection
Jiao, L., Xu, W., Yan, H., Wu, Y., Liu, C., Du, D., Lin, Y., & Zhu, C. (2019) · Analytical Chemistry · doi:10.1021/acs.analchem.9b02901 · Cited by 364
Self-citationFabrication of Single‐Atom Catalysts with Precise Structure and High Metal Loading
Wang, J., Li, Z., Wu, Y., & Li, Y. (2018) · Advanced Materials · doi:10.1002/adma.201801649 · Cited by 337
Self-citationOxidase‐Like Fe‐N‐C Single‐Atom Nanozymes for the Detection of Acetylcholinesterase Activity
Wu, Y., Jiao, L., Luo, X., Xu, W., Wei, X., Wang, H., Yan, H., Gu, W., Xu, B. Z., Du, D., et al. (2019) · Small · doi:10.1002/smll.201903108 · Cited by 324
Self-citationXia, W., Tang, J., Li, J., Zhang, S., Wu, K. C. ‐., He, J., & Yamauchi, Y. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201906870 · Cited by 322
Yi, J.-D., Xu, R., Wu, Q., Zhang, T., Zang, K.-T., Luo, J., Liang, Y.-L., Huang, Y.-B., & Cao, R. (2018) · ACS Energy Letters · doi:10.1021/acsenergylett.8b00245 · Cited by 308
Tan, H., Tang, J., Henzie, J., Li, Y., Xu, X., Chen, T., Wang, Z., Wang, J., Ide, Y., Bando, Y., et al. (2018) · ACS Nano · doi:10.1021/acsnano.8b01502 · Cited by 301
Kim, M. S., Lee, J., Kim, H. S., Cho, A., Shim, K. H., Le, T. N., An, S. S. A., Han, J. W., Kim, M. I., & Lee, J. (2020) · Advanced Functional Materials · doi:10.1002/adfm.201905410 · Cited by 263
Densely Populated Single Atom Catalysts
Wu, J., Xiong, L., Zhao, B., Liu, M., & Huang, L. (2020) · Small Methods · doi:10.1002/smtd.201900540 · Cited by 250
Self-citationTan, H., Li, Y., Kim, J., Takei, T., Wang, Z., Xu, X., Wang, J., Bando, Y., Kang, Y., Tang, J., et al. (2018) · Advanced Science · doi:10.1002/advs.201800120 · Cited by 220
Cheng, Y., He, S., Lu, S., Veder, J., Johannessen, B., Thomsen, L., Saunders, M., Becker, T., De Marco, R., Li, Q., et al. (2019) · Advanced Science · doi:10.1002/advs.201802066 · Cited by 212
Guo, C. X., Zheng, X. T., Lu, Z. S., Lou, X. W., & Li, C. M. (2010) · Advanced Materials · doi:10.1002/adma.201001699 · Cited by 200
Guo, Y., Tang, J., Henzie, J., Jiang, B., Qian, H., Wang, Z., Tan, H., Bando, Y., & Yamauchi, Y. (2017) · Mater. Horiz. · doi:10.1039/c7mh00586e · Cited by 188
Qu, Y., Wang, L., Li, Z., Li, P., Zhang, Q., Lin, Y., Zhou, F., Wang, H., Yang, Z., Hu, Y., et al. (2019) · Advanced Materials · doi:10.1002/adma.201904496 · Cited by 176
Self-citationA dopamine-induced Au hydrogel nanozyme for enhanced biomimetic catalysis
Jiao, L., Xu, W., Yan, H., Wu, Y., Gu, W., Li, H., Du, D., Lin, Y., & Zhu, C. (2019) · Chemical Communications · doi:10.1039/c9cc04436a · Cited by 116
Self-citationA Doubly-Quenched Fluorescent Probe for Low-Background Detection of Mitochondrial H2O2
Liu, J., Liang, J., Wu, C., & Zhao, Y. (2019) · Analytical Chemistry · doi:10.1021/acs.analchem.9b01294 · Cited by 100
Shi, Q., Song, Y., Zhu, C., Yang, H., Du, D., & Lin, Y. (2015) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5b08146 · Cited by 60
Self-citation
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Zhang, S., Li, Y., Sun, S., Liu, L., Mu, X., Liu, S., Jiao, M., Chen, X., Chen, K., Ma, H., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-32411-z · Cited by 280
Defect engineering in nanozymes
Wu, Y., Xu, W., Jiao, L., Tang, Y., Chen, Y., Gu, W., & Zhu, C. (2022) · Materials Today · doi:10.1016/j.mattod.2021.10.032 · Cited by 269
Self-citationWang, H., Fang, Q., Gu, W., Du, D., Lin, Y., & Zhu, C. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.0c14007 · Cited by 95
Self-citation
Metadata
- Authors
- Jiao, L., Wu, J., Zhong, H., Zhang, Y., Xu, W., Wu, Y., Chen, Y., Yan, H., Zhang, Q., Gu, W., Gu, L., Beckman, S. P., Huang, L., & Zhu, C.
- Venue
- ACS Catalysis
- Publisher
- American Chemical Society (ACS)
- Published
- 2020-05-11
- Volume
- 10
- Issue
- 11
- Pages
- 6422-6429
- ISSN
- 2155-5435 (ISSN-L)
- OpenAlex
- W3025370441
- Cited by
- 312
- References
- 46
- FWCI
- 17.53
- Type
- journal article
- Language
- en
- Open access
- closed
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