The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Noninvasive Imaging of Nanomedicines and Nanotheranostics: Principles, Progress, and Prospects
Open accessAbstract
Noninvasive imaging is used for many different (pre)clinical purposes, ranging from disease diagnosis, disease staging, and treatment monitoring to the visualization and quantification of nanomedicine-mediated drug targeting and (triggered) drug release. Noninvasive imaging can be employed to visualize and quantify how efficient passive or active drug targeting is in individual patients and, on this basis, to preselect patients likely to respond to nanomedicine-based chemotherapeutic interventions. In addition, it can be used to visualize the off-target localization of nanomedicines, e.g., in potentially endangered healthy tissues, which under certain circumstances might lead to exclusion from targeted treatment. Moreover, by systematically integrating imaging also during follow-up and by closely monitoring therapeutic responses upon nanomedicine treatment, clinical decision making can be facilitated and improved, as decisions on whether or not to (dis)continue treatment and on whether or not to adjust drug doses can be made relatively early on. Noninvasive imaging may be particularly useful in the case of metastatic disease. By subsequently performing PET or SPECT scans with radionuclide-labeled nanomedicines, information can be obtained on the accumulation of these formulations in both primary tumors and metastases, and treatment protocols can be adapted accordingly.
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Cites
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Cited by
Ghezzi, M., Pescina, S., Padula, C., Santi, P., Del Favero, E., Cantù, L., & Nicoli, S. (2021) · Journal of Controlled Release · doi:10.1016/j.jconrel.2021.02.031 · Cited by 1,135
Bridging Bio–Nano Science and Cancer Nanomedicine
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Ojha, T., Pathak, V., Shi, Y., Hennink, W. E., Moonen, C. T. W., Storm, G., Kiessling, F., & Lammers, T. (2017) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2017.07.007 · Cited by 260
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Self-citationFluorination Enhances NIR‐II Fluorescence of Polymer Dots for Quantitative Brain Tumor Imaging
Liu, Y., Liu, J., Chen, D., Wang, X., Zhang, Z., Yang, Y., Jiang, L., Qi, W., Ye, Z., He, S., et al. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.202007886 · Cited by 173
Metadata
- Authors
- Kunjachan, S., Ehling, J., Storm, G., Kiessling, F., & Lammers, T.
- Venue
- Chemical Reviews
- Publisher
- American Chemical Society (ACS)
- Published
- 2015-07-13
- Volume
- 115
- Issue
- 19
- Pages
- 10907-10937
- ISSN
- 0009-2665 (ISSN-L)
- 1520-6890
- OpenAlex
- W2302405003
- Cited by
- 480
- References
- 11
- FWCI
- 2.00
- Type
- journal article
- Language
- en
- Open access
- green
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- Kunjachan, S., Ehling, J., Storm, G., Kiessling, F., & Lammers, T. (2015). Noninvasive Imaging of Nanomedicines and Nanotheranostics: Principles, Progress, and Prospects. Chemical Reviews. https://doi.org/10.1021/cr500314d
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